Isabelle Baconguis

Assistant Professor

  • 644 Citations
  • 8 h-Index
20072018
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2007 2018

  • 644 Citations
  • 8 h-Index
  • 9 Article
2007
61 Citations (Scopus)

Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems

Wu, H. Y., Hsu, F. C., Gleichman, A. J., Baconguis, I., Coulter, D. A. & Lynch, D. R., Jul 13 2007, In : Journal of Biological Chemistry. 282, 28, p. 20075-20087 13 p.

Research output: Contribution to journalArticle

Phosphorylation
Calpain
Neurons
N-Methyl-D-Aspartate Receptors
Neuronal Plasticity
24 Citations (Scopus)

N-methyl-D-aspartate receptor-dependent regulation of the glutamate transporter excitatory amino acid carrier 1

Waxman, E. A., Baconguis, I., Lynch, D. R. & Robinson, M. B., Jun 15 2007, In : Journal of Biological Chemistry. 282, 24, p. 17594-17607 14 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
Excitatory Amino Acids
N-Methyl-D-Aspartate Receptors
Isoxazoles
N-Methylaspartate
2010
60 Citations (Scopus)

Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model

Larsson, H. P., Wang, X., Lev, B., Baconguis, I., Caplan, D. A., Vyleta, N. P., Koch, H. P., Diez-Sampedro, A. & Noskov, S. Y., Aug 3 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 31, p. 13912-13917 6 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
Sodium
Binding Sites
Glutamic Acid
Ions
2012
158 Citations (Scopus)

Structural plasticity and dynamic selectivity of acid-sensing ion channelspider toxin complexes

Baconguis, I. & Gouaux, E., Sep 20 2012, In : Nature. 489, 7416, p. 400-405 6 p.

Research output: Contribution to journalArticle

Acid Sensing Ion Channels
Ions
Acids
Physiological Phenomena
Nociception
2013
27 Citations (Scopus)
Acid Sensing Ion Channels
Ligand-Gated Ion Channels
Adenosine Triphosphate
Purinergic P2X4 Receptors
Ion Channels
2014
126 Citations (Scopus)

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

Goehring, A., Lee, C. H., Wang, K. H., Michel, J. C., Claxton, D. P., Baconguis, I., Althoff, T., Fischer, S., Garcia, K. C. & Gouaux, E., Nov 27 2014, In : Nature Protocols. 9, 11, p. 2574-2585 12 p.

Research output: Contribution to journalArticle

Baculoviridae
Screening
Membrane Proteins
Cells
Acid Sensing Ion Channels
135 Citations (Scopus)

X-ray structure of acid-sensing ion channel 1-snake toxin complex reveals open state of a Na+-selective channel

Baconguis, I., Bohlen, C. J., Goehring, A., Julius, D. & Gouaux, E., Feb 13 2014, In : Cell. 156, 4, p. 717-729 13 p.

Research output: Contribution to journalArticle

Acid Sensing Ion Channels
Snakes
Degenerin Sodium Channels
X-Rays
Epithelial Sodium Channels
2016
46 Citations (Scopus)

Architecture of fully occupied GluA2 AMPA receptor-TARP complex elucidated by cryo-EM

Zhao, Y., Chen, S., Yoshioka, C., Baconguis, I. & Gouaux, E., Jul 1 2016, In : Nature. 536, 7614, p. 108-111 4 p.

Research output: Contribution to journalArticle

Cryoelectron Microscopy
AMPA Receptors
Proteins
Ligands
Ion Channels
2018
7 Citations (Scopus)

Structure of the human epithelial sodium channel by cryo-electron microscopy

Noreng, S., Bharadwaj, A., Posert, R., Yoshioka, C. & Baconguis, I., Sep 25 2018, In : eLife. 7

Research output: Contribution to journalArticle

Epithelial Sodium Channels
Cryoelectron Microscopy
Thumb
Electron microscopy
Fingers