Isabelle Baconguis

Assistant Professor

Assistant Professor, Vollum Institute

Emailbacongui@ohsu.edu

581 Citations
8 h-Index

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3 Similar Profiles

Acid Sensing Ion Channels Medicine & Life Sciences

Cryoelectron Microscopy Medicine & Life Sciences

Amino Acid Transport System X-AG Medicine & Life Sciences

Epithelial Sodium Channels Medicine & Life Sciences

Ions Medicine & Life Sciences

N-Methyl-D-Aspartate Receptors Medicine & Life Sciences

Excitatory Amino Acids Medicine & Life Sciences

Phosphorylation Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2011 2018

2 Finished

Structure and Function of Epithelial Sodium Channels

Baconguis, I.

National Institutes of Health

9/19/13 → 8/31/18

Project: Research project

Epithelial Sodium Channels

X-Rays

Ion Channels

Proteolysis

Hypertension

3D Structure of Acid-sensing Ion Channel in the Open State

Baconguis, I.

National Institutes of Health

4/1/11 → 3/31/13

Project: Research project

Acid Sensing Ion Channels

Stroke

X ray crystallography

Chickens

X Ray Crystallography

Research Output 2007 2018

581 Citations
8 h-Index
9 Article

1 Citation (Scopus)

Structure of the human epithelial sodium channel by cryo-electron microscopy

Noreng, S., Bharadwaj, A., Posert, R., Yoshioka, C. & Baconguis, I., Sep 25 2018, In : eLife. 7

Research output: Contribution to journal › Article

Epithelial Sodium Channels

Cryoelectron Microscopy

Thumb

Electron microscopy

Fingers

38 Citations (Scopus)

Architecture of fully occupied GluA2 AMPA receptor-TARP complex elucidated by cryo-EM

Zhao, Y., Chen, S., Yoshioka, C., Baconguis, I. & Gouaux, E., Jul 1 2016, In : Nature. 536, 7614, p. 108-111 4 p.

Research output: Contribution to journal › Article

Cryoelectron Microscopy

AMPA Receptors

Proteins

Ligands

Ion Channels

106 Citations (Scopus)

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

Goehring, A., Lee, C. H., Wang, K. H., Michel, J. C., Claxton, D. P., Baconguis, I., Althoff, T., Fischer, S., Garcia, K. C. & Gouaux, E., Nov 27 2014, In : Nature Protocols. 9, 11, p. 2574-2585 12 p.

Research output: Contribution to journal › Article

Baculoviridae

Screening

Membrane Proteins

Cells

Acid Sensing Ion Channels

120 Citations (Scopus)

X-ray structure of acid-sensing ion channel 1-snake toxin complex reveals open state of a Na+-selective channel

Baconguis, I., Bohlen, C. J., Goehring, A., Julius, D. & Gouaux, E., Feb 13 2014, In : Cell. 156, 4, p. 717-729 13 p.

Research output: Contribution to journal › Article

Acid Sensing Ion Channels

Snakes

Degenerin Sodium Channels

X-Rays

Epithelial Sodium Channels

26 Citations (Scopus)

Unanticipated parallels in architecture and mechanism between ATP-gated P2X receptors and acid sensing ion channels

Baconguis, I., Hattori, M. & Gouaux, E., Apr 2013, In : Current Opinion in Structural Biology. 23, 2, p. 277-284 8 p.

Research output: Contribution to journal › Article

Acid Sensing Ion Channels

Ligand-Gated Ion Channels

Adenosine Triphosphate

Purinergic P2X4 Receptors

Ion Channels