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Isabelle Baconguis

Assistant Professor

  • 544 Citations
  • 8 h-Index
20072018
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  • 3 Similar Profiles
Acid Sensing Ion Channels Medicine & Life Sciences
Cryoelectron Microscopy Medicine & Life Sciences
Amino Acid Transport System X-AG Medicine & Life Sciences
Epithelial Sodium Channels Medicine & Life Sciences
Ions Medicine & Life Sciences
N-Methyl-D-Aspartate Receptors Medicine & Life Sciences
Excitatory Amino Acids Medicine & Life Sciences
Phosphorylation Chemical Compounds

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Projects 2011 2018

Structure and Function of Epithelial Sodium Channels

Baconguis, I.

National Institutes of Health

9/19/13 → 8/31/18

Project: Research project › Early Independence Award

Epithelial Sodium Channels
X-Rays
Ion Channels
Proteolysis
Hypertension

3D Structure of Acid-sensing Ion Channel in the Open State

Baconguis, I.

National Institutes of Health

4/1/11 → 3/31/13

Project: Research project › Predoctoral Individual National Research Service Award

Acid Sensing Ion Channels
Stroke
X ray crystallography
Chickens
X Ray Crystallography

Research Output 2007 2018

  • 544 Citations
  • 8 h-Index
  • 9 Article

Structure of the human epithelial sodium channel by cryo-electron microscopy

Noreng, S., Bharadwaj, A., Posert, R., Yoshioka, C. & Baconguis, I., Sep 25 2018, In : eLife. 7

Research output: Contribution to journal › Article

Epithelial Sodium Channels
Cryoelectron Microscopy
Thumb
Electron microscopy
Fingers
34 Citations

Architecture of fully occupied GluA2 AMPA receptor-TARP complex elucidated by cryo-EM

Zhao, Y., Chen, S., Yoshioka, C., Baconguis, I. & Gouaux, E., Jul 1 2016, In : Nature. 536, 7614, p. 108-111 4 p.

Research output: Contribution to journal › Article

Cryoelectron Microscopy
AMPA Receptors
Proteins
Ligands
Ion Channels
93 Citations

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

Goehring, A., Lee, C. H., Wang, K. H., Michel, J. C., Claxton, D. P., Baconguis, I., Althoff, T., Fischer, S., Garcia, K. C. & Gouaux, E., Nov 27 2014, In : Nature Protocols. 9, 11, p. 2574-2585 12 p.

Research output: Contribution to journal › Article

Baculoviridae
Screening
Membrane Proteins
Cells
Acid Sensing Ion Channels
110 Citations

X-ray structure of acid-sensing ion channel 1-snake toxin complex reveals open state of a Na+-selective channel

Baconguis, I., Bohlen, C. J., Goehring, A., Julius, D. & Gouaux, E., Feb 13 2014, In : Cell. 156, 4, p. 717-729 13 p.

Research output: Contribution to journal › Article

Acid Sensing Ion Channels
Snakes
Degenerin Sodium Channels
X-Rays
Epithelial Sodium Channels
26 Citations

Unanticipated parallels in architecture and mechanism between ATP-gated P2X receptors and acid sensing ion channels

Baconguis, I., Hattori, M. & Gouaux, E., Apr 2013, In : Current Opinion in Structural Biology. 23, 2, p. 277-284 8 p.

Research output: Contribution to journal › Article

Acid Sensing Ion Channels
Ligand-Gated Ion Channels
Adenosine Triphosphate
Purinergic P2X4 Receptors
Ion Channels