Holly Rosenzweig

Associate Professor

  • 1328 Citations
  • 18 h-Index
20032019

Research output per year

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Research Output

  • 1328 Citations
  • 18 h-Index
  • 30 Article
  • 3 Review article
  • 1 Chapter
  • 1 Short survey
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Article
2018

Nod2 deficiency augments Th17 responses and exacerbates autoimmune arthritis

Napier, R. J., Lee, E., Vance, E. E., Snow, P. E., Samson, K. A., Dawson, C. E., Moran, A., Stenzel, P., Davey, M., Sakaguchi, S. & Rosenzweig, H., Oct 1 2018, In : Journal of Immunology. 201, 7, p. 1889-1898 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Fungal-derived cues promote ocular autoimmunity through a Dectin-2/Card9-mediated mechanism

Brown, B. R., Lee, E. J., Snow, P. E., Vance, E. E., Iwakura, Y., Ohno, N., Miura, N., Lin, X., Brown, G. D., Wells, C. A., Smith, J. R., Caspi, R. R. & Rosenzweig, H. L., Dec 2017, In : Clinical and Experimental Immunology. 190, 3, p. 293-303 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2016

Mincle activation and the Syk/Card9 signaling axis are central to the development of autoimmune disease of the eye

Lee, E., Brown, B. R., Vance, E. E., Snow, P. E., Silver, P. B., Heinrichs, D., Lin, X., Iwakura, Y., Wells, C. A., Caspi, R. R. & Rosenzweig, H., Apr 1 2016, In : Journal of Immunology. 196, 7, p. 3148-3158 11 p.

Research output: Contribution to journalArticle

29 Scopus citations
2015

Aberrant interleukin-1 signalling does not increase susceptibility of mice to NOD2-dependent uveitis

Lee, E. J., Allensworth, J. J., Clowers, J. S. & Rosenzweig, H. L., May 1 2015, In : Clinical and Experimental Ophthalmology. 43, 4, p. 349-357 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Blau syndrome-associated Nod2 mutation alters expression of full-length NOD2 and limits responses to muramyl dipeptide in knock-in mice

Dugan, J., Griffiths, E., Snow, P., Rosenzweig, H., Lee, E., Brown, B., Carr, D. W., Rose, C., Rosenbaum, J. & Davey, M. P., Jan 1 2015, In : Journal of Immunology. 194, 1, p. 349-357 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Investigation of the relationship between the onset of arthritis and uveitis in genetically predisposed SKG mice

Lee, E. J., Vance, E. E., Brown, B. R., Snow, P. S., Clowers, J. S., Sakaguchi, S. & Rosenzweig, H. L., Aug 19 2015, In : Arthritis Research and Therapy. 17, 1, 218.

Research output: Contribution to journalArticle

3 Scopus citations
2013

Investigation of the peptidoglycan sensing molecule, PGLYRP-2, in murine inflammatory uveitis

Clowers, J. S., Allensworth, J. J., Lee, E. J. & Rosenzweig, H. L., Apr 1 2013, In : British Journal of Ophthalmology. 97, 4, p. 504-510 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2012

Impact of IL-1 signalling on experimental uveitis and arthritis

Planck, S. R., Woods, A., Clowers, J. S., Nicklin, M. J., Rosenbaum, J. T. & Rosenzweig, H. L., May 1 2012, In : Annals of the rheumatic diseases. 71, 5, p. 753-760 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
18 Scopus citations
23 Scopus citations

The NLRP3 inflammasome is active but not essential in endotoxin-induced uveitis

Rosenzweig, H. L., Woods, A., Clowers, J. S., Planck, S. R. & Rosenbaum, J. T., Mar 1 2012, In : Inflammation Research. 61, 3, p. 225-231 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2011

Contrasting Ocular Effects of Local versus Systemic Endotoxin

Rosenbaum, J. T., Woods, A., Kezic, J., Planck, S. R. & Rosenzweig, H. L., Aug 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 9, p. 6472-6477 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Dectin-1 and NOD2 mediate cathepsin activation in zymosan-induced arthritis in mice

Rosenzweig, H. L., Clowers, J. S., Nunez, G., Rosenbaum, J. T. & Davey, M. P., Jul 1 2011, In : Inflammation Research. 60, 7, p. 705-714 10 p.

Research output: Contribution to journalArticle

15 Scopus citations
18 Scopus citations

Investigation of the differential potentials of TLR agonists to elicit uveitis in mice

Allensworth, J. J., Planck, S. R., Rosenbaum, J. T. & Rosenzweig, H. L., Dec 1 2011, In : Journal of Leukocyte Biology. 90, 6, p. 1159-1166 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

NOD2 deficiency results in increased susceptibility to peptidoglycan-induced uveitis in mice

Rosenzweig, H. L., Galster, K., Vance, E. E., Ensign-Lewis, J., Nunez, G., Davey, M. P. & Rosenbaum, J. T., Jun 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 7, p. 4106-4112 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
2010
27 Scopus citations
2009

Activation of nucleotide oligomerization domain 2 exacerbates a murine model of proteoglycan-induced arthritis

Rosenzweig, H. L., Jann, M. M., Glant, T. T., Martin, T. M., Planck, S. R., Van Eden, W., Van Kooten, P. J. S., Flavell, R. A., Kobayashi, K. S., Rosenbaum, J. T. & Davey, M. P., Apr 1 2009, In : Journal of Leukocyte Biology. 85, 4, p. 711-718 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance

Farkas, B., Boldizsar, F., Tarjanyi, O., Laszlo, A., Lin, S. M., Hutas, G., Tryniszewska, B., Mangold, A., Nagyeri, G., Rosenzweig, H. L., Finnegan, A., Mikecz, K. & Glant, T. T., Feb 16 2009, In : Arthritis Research and Therapy. 11, 1, R21.

Research output: Contribution to journalArticle

12 Scopus citations
27 Scopus citations
33 Scopus citations

Nucleotide oligomerization domain-2 interacts with 2′-5′-oligoadenylate synthetase type 2 and enhances RNase-L function in THP-1 cells

Dugan, J. W., Albor, A., David, L., Fowlkes, J., Blackledge, M. T., Martin, T. M., Planck, S. R., Rosenzweig, H. L., Rosenbaum, J. T. & Davey, M. P., Dec 1 2009, In : Molecular Immunology. 47, 2-3, p. 560-566 7 p.

Research output: Contribution to journalArticle

35 Scopus citations
2008
29 Scopus citations

Anterior uveitis accompanies joint disease in a murine model resembling ankylosing spondylitis

Rosenzweig, H. L., Martin, T. M., Planck, S. R., Jann, M. M., Smith, J. R., Glant, T. T., Van Eden, W., Davey, M. P. & Rosenbaum, J. T., Apr 1 2008, In : Ophthalmic Research. 40, 3-4, p. 189-192 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

NOD2, the gene responsible for familial granulomatous uveitis, in a mouse model of uveitis

Rosenzweig, H. L., Martin, T. M., Jann, M. M., Planck, S. R., Davey, M. P., Kobayashi, K., Flavell, R. A. & Rosenbaum, J. T., Apr 1 2008, In : Investigative Ophthalmology and Visual Science. 49, 4, p. 1518-1524 7 p.

Research output: Contribution to journalArticle

34 Scopus citations
2007

Endotoxin preconditioning protects against the cytotoxic effects of TNFα after stroke: A novel role for TNFα in LPS-ischemic tolerance

Rosenzweig, H. L., Minami, M., Lessov, N. S., Coste, S. C., Stevens, S. L., Henshall, D. C., Meller, R., Simon, R. P. & Stenzel-Poore, M. P., Oct 1 2007, In : Journal of Cerebral Blood Flow and Metabolism. 27, 10, p. 1663-1674 12 p.

Research output: Contribution to journalArticle

119 Scopus citations
2005

Neuroprotection by osteopontin in stroke

Meller, R., Stevens, S. L., Minami, M., Cameron, J. A., King, S., Rosenzweig, H., Doyle, K., Lessov, N. S., Simon, R. P. & Stenzel-Poore, M. P., Feb 1 2005, In : Journal of Cerebral Blood Flow and Metabolism. 25, 2, p. 217-225 9 p.

Research output: Contribution to journalArticle

140 Scopus citations
2004

Endotoxin preconditioning prevents cellular inflammatory response during ischemic neuroprotection in mice

Rosenzweig, H. L., Lessov, N. S., Henshall, D. C., Minami, M., Simon, R. P. & Stenzel-Poore, M. P., Nov 1 2004, In : Stroke. 35, 11, p. 2576-2581 6 p.

Research output: Contribution to journalArticle

178 Scopus citations

Overproduction of corticotropin-releasing hormone blocks germinal center formation: Role of corticosterone and impaired follicular dendritic cell networks

Murray, S. E., Rosenzweig, H. L., Johnson, M., Huising, M. O., Sawicki, K. & Stenzel-Poore, M. P., Nov 2004, In : Journal of Neuroimmunology. 156, 1-2, p. 31-41 11 p.

Research output: Contribution to journalArticle

16 Scopus citations
2003

Effect of ischaemic preconditioning on genomic response to cerebral ischaemia: Similarity to neuroprotective strategies in hibernation and hypoxia-tolerant states

Stenzel-Poore, M. P., Stevens, S. L., Xiong, Z., Lessov, N. S., Harrington, C. A., Mori, M., Meller, R., Rosenzweig, H. L., Tobar, E., Shaw, T. E., Chu, X. & Simon, R. P., Sep 27 2003, In : Lancet. 362, 9389, p. 1028-1037 10 p.

Research output: Contribution to journalArticle

341 Scopus citations