Haining Zhong

Associate Professor

  • 1680 Citations
  • 16 h-Index
19962019
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Research Output 1996 2019

  • 1680 Citations
  • 16 h-Index
  • 27 Article
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Article
2019

Dynamic assembly of ribbon synapses and circuit maintenance in a vertebrate sensory system

Okawa, H., Yu, W. Q., Matti, U., Schwarz, K., Odermatt, B., Zhong, H., Tsukamoto, Y., Lagnado, L., Rieke, F., Schmitz, F. & Wong, R. O. L., Dec 1 2019, In : Nature communications. 10, 1, 2167.

Research output: Contribution to journalArticle

Open Access
synapses
vertebrates
Synapses
ribbons
maintenance
Optical Imaging
Cyclic AMP-Dependent Protein Kinases
Photons
Microscopy
Microscopic examination
2018
6 Citations (Scopus)

A Highly Sensitive A-Kinase Activity Reporter for Imaging Neuromodulatory Events in Awake Mice

Ma, L., Jongbloets, B. C., Xiong, W-H., Melander, J. B., Qin, M., Lameyer, T. J., Harrison, M. F., Zemelman, B. V., Mao, T. & Zhong, H., Aug 22 2018, In : Neuron. 99, 4, p. 665-679.e5

Research output: Contribution to journalArticle

Protein Kinases
Phosphotransferases
Optical Imaging
Photons
Neurotransmitter Agents
64 Citations (Scopus)

Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors

Patriarchi, T., Cho, J. R., Merten, K., Howe, M. W., Marley, A., Xiong, W-H., Folk, R. W., Broussard, G. J., Liang, R., Jang, M. J., Zhong, H., Dombeck, D., von Zastrow, M., Nimmerjahn, A., Gradinaru, V., Williams, J. & Tian, L., May 31 2018, (Accepted/In press) In : Science. p. 1-14 14 p.

Research output: Contribution to journalArticle

Dopamine
Optogenetics
Learning
Melatonin
Neuropeptides
2017
11 Citations (Scopus)

Liberated PKA Catalytic Subunits Associate with the Membrane via Myristoylation to Preferentially Phosphorylate Membrane Substrates

Tillo, S. E., Xiong, W-H., Takahashi, M., Miao, S., Andrade, A. L., Fortin, D. A., Yang, G., Qin, M., Smoody, B. F., Stork, P. & Zhong, H., Apr 18 2017, In : Cell Reports. 19, 3, p. 617-629 13 p.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinases
Catalytic Domain
Membranes
Substrates
Protein Kinase C
9 Citations (Scopus)

Ontogenetic establishment of order-specific nuclear organization in the mammalian thalamus

Shi, W., Xianyu, A., Han, Z., Tang, X., Li, Z., Zhong, H., Mao, T., Huang, K. & Shi, S. H., Mar 29 2017, In : Nature Neuroscience. 20, 4, p. 516-528 13 p.

Research output: Contribution to journalArticle

Thalamus
Organizations
Cognition
Thalamic Nuclei
Hedgehogs
2016
76 Citations (Scopus)

A comprehensive excitatory input map of the striatum reveals novel functional organization

Hunnicutt, B. J., Jongbloets, B. C., Birdsong, W. T., Gertz, K. J., Zhong, H. & Mao, T., Nov 28 2016, In : eLife. 5, November2016, e19103.

Research output: Contribution to journalArticle

Corpus Striatum
Thalamus
Optogenetics
Basal Ganglia
Experiments
2015
9 Citations (Scopus)

Applying superresolution localization-based microscopy to neurons

Zhong, H., May 1 2015, In : Synapse. 69, 5, p. 283-294 12 p.

Research output: Contribution to journalArticle

Microscopy
Neurons
Neurosciences
Brain
Light
2014
43 Citations (Scopus)

A comprehensive thalamocortical projection map at the mesoscopic level

Hunnicutt, B. J., Long, B. R., Kusefoglu, D., Gertz, K. J., Zhong, H. & Mao, T., Sep 1 2014, In : Nature Neuroscience. 17, 9, p. 1276-1285 10 p.

Research output: Contribution to journalArticle

Thalamus
Optogenetics
Injections
Executive Function
Synapses
20 Citations (Scopus)

Live imaging of endogenous PSD-95 using ENABLED: A conditional strategy to fluorescently label endogenous proteins

Fortin, D. A., Tillo, S. E., Yang, G., Rah, J. C., Melander, J. B., Bai, S., Soler-Cedeño, O., Qin, M., Zemelman, B. V., Guo, C., Mao, T. & Zhong, H., Dec 10 2014, In : Journal of Neuroscience. 34, 50, p. 16698-16712 15 p.

Research output: Contribution to journalArticle

Exons
Neurons
Proteins
Parvalbumins
Dendritic Spines
7 Citations (Scopus)

Subdiffractive microscopy: Techniques, applications, and challenges

Long, B. R., Robinson, D. C. & Zhong, H., Mar 2014, In : Wiley Interdisciplinary Reviews: Systems Biology and Medicine. 6, 2, p. 151-168 18 p.

Research output: Contribution to journalArticle

Microscopy
Microscopic examination
Macromolecular Substances
Molecular Dynamics Simulation
Fluorescence
2010
8 Citations (Scopus)
Optical microscopy
Microscopy
2009
169 Citations (Scopus)

Photon capture and signalling by melanopsin retinal ganglion cells

Do, M. T. H., Kang, S. H., Xue, T., Zhong, H., Liao, H. W., Bergles, D. E. & Yau, K. W., Jan 15 2009, In : Nature. 457, 7227, p. 281-287 7 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Photons
Pupillary Reflex
Light
Vertebrate Photoreceptor Cells
72 Citations (Scopus)

Subcellular Dynamics of Type II PKA in Neurons

Zhong, H., Sia, G. M., Sato, T. R., Gray, N. W., Mao, T., Khuchua, Z., Huganir, R. L. & Svoboda, K., May 14 2009, In : Neuron. 62, 3, p. 363-374 12 p.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinase Type II
Cyclic AMP-Dependent Protein Kinases
Neurons
Protein Kinases
Dendritic Spines
2008
89 Citations (Scopus)

Advances in the speed and resolution of light microscopy

Ji, N., Shroff, H., Zhong, H. & Betzig, E., Dec 2008, In : Current Opinion in Neurobiology. 18, 6, p. 605-616 12 p.

Research output: Contribution to journalArticle

Microscopy
Light
Fluorescence Microscopy
Electrons
Technology
183 Citations (Scopus)

A genetically encoded fluorescent sensor of ERK activity

Harvey, C. D., Ehrhardt, A. G., Cellurale, C., Zhong, H., Yasuda, R., Davis, R. J. & Svoboda, K., Dec 9 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 49, p. 19264-19269 6 p.

Research output: Contribution to journalArticle

Extracellular Signal-Regulated MAP Kinases
Pyramidal Cells
HEK293 Cells
Optical Imaging
Signal-To-Noise Ratio
260 Citations (Scopus)

The spread of Ras activity triggered by activation of a single dendritic spine

Harvey, C. D., Yasuda, R., Zhong, H. & Svoboda, K., Jul 4 2008, In : Science. 321, 5885, p. 136-140 5 p.

Research output: Contribution to journalArticle

Dendritic Spines
Spine
Dendrites
Long-Term Potentiation
N-Methyl-D-Aspartate Receptors
2006

Erratum: Supersensitive Ras activation in dendrites and spines revealed by two-photon fluorescence lifetime imaging (Nature Neuroscience (2006) 9 (283-291))

Yasuda, R., Harvey, C. D., Zhong, H., Sobczyk, A., Van Aelst, L. & Svoboda, K., Mar 2006, In : Nature Neuroscience. 9, 3, p. 453 1 p.

Research output: Contribution to journalArticle

Optical Imaging
Neurosciences
Dendrites
Photons
Spine
175 Citations (Scopus)

Supersensitive Ras activation in dendrites and spines revealed by two-photon fluorescence lifetime imaging

Yasuda, R., Harvey, C. D., Zhong, H., Sobczyk, A., Van Aelst, L. & Svoboda, K., Feb 2006, In : Nature Neuroscience. 9, 2, p. 283-291 9 p.

Research output: Contribution to journalArticle

Optical Imaging
Dendrites
Photons
Spine
ras Proteins
2005
98 Citations (Scopus)

Intrinsically photosensitive retinal ganglion cells detect light with a vitamin A-based photopigment, melanopsin

Fu, Y., Zhong, H., Wang, M. H. H., Luo, D. G., Liao, H. W., Maeda, H., Hattar, S., Frishman, L. J. & Yau, K. W., Jul 19 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 29, p. 10339-10344 6 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Vitamin A
Light
Vertebrate Photoreceptor Cells
Pupillary Reflex
2003
39 Citations (Scopus)

Selective heteromeric assembly of cyclic nucleotide-gated channels

Zhong, H., Lai, J. & Yau, K. W., Apr 29 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 9, p. 5509-5513 5 p.

Research output: Contribution to journalArticle

Cyclic Nucleotide-Gated Cation Channels
Leucine Zippers
Ion Channels
2002
164 Citations (Scopus)

The heteromeric cyclic nucleotide-gated channel adopts a 3A: 1B stoichlometry

Zhong, H., Molday, L. L., Molday, R. S. & Yau, K. W., Nov 14 2002, In : Nature. 420, 6912, p. 193-198 6 p.

Research output: Contribution to journalArticle

Cyclic Nucleotide-Gated Cation Channels
Leucine Zippers
Centrifugation
Leucine
Electrophoresis
2001
99 Citations (Scopus)

Central role of the CNGA4 channel subunit in Ca2+-calmodulin-dependent odor adaptation

Munger, S. D., Lane, A. P., Zhong, H., Leinders-Zufall, T., Yau, K. W., Zufall, F. & Reed, R. R., Dec 7 2001, In : Science. 294, 5549, p. 2172-2175 4 p.

Research output: Contribution to journalArticle

Calmodulin
Cyclic Nucleotide-Gated Cation Channels
Olfactory Receptor Neurons
Cyclic Nucleotides
Signal Transduction
1999
32 Citations (Scopus)

Molecular determinants of the modulation of cyclic nucleotide-activated channels by calmodulin

Grunwald, M. E., Zhong, H., Lai, J. & Yau, K. W., Nov 9 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 23, p. 13444-13449 6 p.

Research output: Contribution to journalArticle

Cyclic Nucleotides
Calmodulin
Binding Sites
Proteins
Cyclic Nucleotide-Gated Cation Channels
1997
25 Citations (Scopus)

Catalysis of the refolding of urea denatured creatine kinase by peptidyl-prolyl cis-trans isomerase

Yang, H. P., Zhong, H. & Zhou, H. M., Apr 4 1997, In : Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology. 1338, 2, p. 147-150 4 p.

Research output: Contribution to journalArticle

Peptidylprolyl Isomerase
Creatine Kinase
Catalysis
Urea
Isomerization
8 Citations (Scopus)

Salt-induced folding of alkaline denatured creatine kinase under high pH conditions

Yang, H. P., Zhong, H., Li, S. & Zhou, H. M., Feb 1997, In : Biochemistry and Molecular Biology International. 41, 2, p. 257-267 11 p.

Research output: Contribution to journalArticle

Creatine Kinase
Salts
Fluorescence
Protein folding
Enzymes
1996
14 Citations (Scopus)

Alkaline unfolding and salt-induced folding of yeast alcohol dehydrogenase under high pH conditions

Wei-Ping, L. E., Yan, S. X., Sen, L. I., Zhong, H. & Zhou, H. M., 1996, In : International Journal of Peptide and Protein Research. 47, 6, p. 484-490 7 p.

Research output: Contribution to journalArticle

Alcohol Dehydrogenase
Salts
Enzymes
Molecules
Aptitude