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20032021

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  • 2021

    CIDO ontology updates and secondary analysis of host responses to COVID-19 infection based on ImmPort reports and literature

    Huffman, A., Masci, A. M., Zheng, J., Sanati, N., Brunson, T., Wu, G. & He, Y., Dec 2021, In: Journal of Biomedical Semantics. 12, 1, 18.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms

    the COVID-19 Disease Map Community, Oct 2021, In: Molecular Systems Biology. 17, 10, e10387.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    14 Scopus citations
  • Using Reactome to build an autophagy mechanism knowledgebase

    Varusai, T. M., Jupe, S., Sevilla, C., Matthews, L., Gillespie, M., Stein, L., Wu, G., D’Eustachio, P., Metzakopian, E. & Hermjakob, H., 2021, In: Autophagy. 17, 6, p. 1543-1554 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • VaximmutorDB: A Web-Based Vaccine Immune Factor Database and Its Application for Understanding Vaccine-Induced Immune Mechanisms

    Berke, K., Sun, P., Ong, E., Sanati, N., Huffman, A., Brunson, T., Loney, F., Ostrow, J., Racz, R., Zhao, B., Xiang, Z., Masci, A. M., Zheng, J., Wu, G. & He, Y., Mar 12 2021, In: Frontiers in immunology. 12, 639491.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • 2020

    Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

    PCAWG Drivers and Functional Interpretation Working Group, PCAWG Structural Variation Working Group & PCAWG Consortium, Feb 6 2020, In: Nature. 578, 7793, p. 102-111 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    206 Scopus citations
  • Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

    PCAWG Drivers and Functional Interpretation Group & PCAWG Consortium, Dec 1 2020, In: Communications Biology. 3, 1, 56.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    84 Scopus citations
  • Combined burden and functional impact tests for cancer driver discovery using DriverPower

    PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 734.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    14 Scopus citations
  • Integrative pathway enrichment analysis of multivariate omics data

    PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 735.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    48 Scopus citations
  • Pan-cancer analysis of whole genomes

    The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Feb 6 2020, In: Nature. 578, 7793, p. 82-93 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    896 Scopus citations
  • Pathway and network analysis of more than 2500 whole cancer genomes

    PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 729.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    37 Scopus citations
  • Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

    MC3 Working Group, PCAWG novel somatic mutation calling methods working group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 4748.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • Sex differences in oncogenic mutational processes

    PCAWG Tumour Subtypes and Clinical Translation & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 4330.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    28 Scopus citations
  • The reactome pathway knowledgebase

    Jassal, B., Matthews, L., Viteri, G., Gong, C., Lorente, P., Fabregat, A., Sidiropoulos, K., Cook, J., Gillespie, M., Haw, R., Loney, F., May, B., Milacic, M., Rothfels, K., Sevilla, C., Shamovsky, V., Shorser, S., Varusai, T., Weiser, J., Wu, G., & 3 othersStein, L., Hermjakob, H. & D'Eustachio, P., Jan 1 2020, In: Nucleic acids research. 48, D1, p. D498-D503

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1046 Scopus citations
  • 2019

    Acute myeloid leukemia–induced T-cell suppression can be reversed by inhibition of the MAPK pathway

    Moshofsky, K. B., Cho, H. J., Wu, G., Romine, K. A., Newman, M. T., Kosaka, Y., McWeeney, S. K. & Lind, E. F., Oct 22 2019, In: Blood Advances. 3, 20, p. 3038-3051 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • Natural product target network reveals potential for cancer combination therapies

    Chamberlin, S. R., Blucher, A., Wu, G., Shinto, L., Choonoo, G., Kulesz-Martin, M. & McWeeney, S., 2019, In: Frontiers in Pharmacology. 10, MAY, 557.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    27 Scopus citations
  • Reactome and ORCID-fine-grained credit attribution for community curation

    Viteri, G., Matthews, L., Varusai, T., Gillespie, M., Milacic, M., Cook, J., Weiser, J., Shorser, S., Sidiropoulos, K., Fabregat, A., Haw, R., Wu, G., Stein, L., D'Eustachio, P. & Hermjakob, H., Jan 1 2019, In: Database : the journal of biological databases and curation. 2019

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • VIO: Ontology classification and study of vaccine responses given various experimental and analytical conditions

    Ong, E., Sun, P., Berke, K., Zheng, J., Wu, G. & He, Y., Dec 23 2019, In: BMC bioinformatics. 20, 704.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • 2018

    Automation of ReactomeFIViz via CyREST API

    Wu, G. & Loney, F., 2018, In: F1000Research. 7, 531.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Network-based predictors of progression in head and neck squamous cell carcinoma

    Sanati, N., Iancu, O., Wu, G., Jacobs, J. E. & McWeeney, S. K., May 29 2018, In: Frontiers in Genetics. 9, MAY, 183.

    Research output: Contribution to journalArticlepeer-review

    14 Scopus citations
  • Reactome graph database: Efficient access to complex pathway data

    Fabregat, A., Korninger, F., Viteri, G., Sidiropoulos, K., Marin-Garcia, P., Ping, P., Wu, G., Stein, L., D’Eustachio, P. & Hermjakob, H., Jan 2018, In: PLoS computational biology. 14, 1, e1005968.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    100 Scopus citations
  • The Reactome Pathway Knowledgebase

    Fabregat, A., Jupe, S., Matthews, L., Sidiropoulos, K., Gillespie, M., Garapati, P., Haw, R., Jassal, B., Korninger, F., May, B., Milacic, M., Roca, C. D., Rothfels, K., Sevilla, C., Shamovsky, V., Shorser, S., Varusai, T., Viteri, G., Weiser, J., Wu, G., & 3 othersStein, L., Hermjakob, H. & D'Eustachio, P., Jan 1 2018, In: Nucleic acids research. 46, D1, p. D649-D655

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1387 Scopus citations
  • 2017

    Comprehensive definition of human immunodominant CD8 antigens in tuberculosis

    Lewinsohn, D. A., Swarbrick, G. M., Park, B., Cansler, M. E., Null, M. D., Toren, K. G., Baseke, J., Zalwango, S., Mayanja-Kizza, H., Malone, L. L., Nyendak, M., Wu, G., Guinn, K., McWeeney, S., Mori, M., Chervenak, K. A., Sherman, D. R., Boom, W. H. & Lewinsohn, D. M., Dec 1 2017, In: npj Vaccines. 2, 1, 8.

    Research output: Contribution to journalArticlepeer-review

    24 Scopus citations
  • Plant Reactome: A resource for plant pathways and comparative analysis

    Naithani, S., Preece, J., D'Eustachio, P., Gupta, P., Amarasinghe, V., Dharmawardhana, P. D., Wu, G., Fabregat, A., Elser, J. L., Weiser, J., Keays, M., Fuentes, A. M. P., Petryszak, R., Stein, L. D., Ware, D. & Jaiswal, P., Jan 1 2017, In: Nucleic acids research. 45, D1, p. D1029-D1039

    Research output: Contribution to journalArticlepeer-review

    Open Access
    39 Scopus citations
  • 2016

    Reactome from a WikiPathways Perspective

    Bohler, A., Wu, G., Kutmon, M., Pradhana, L. A., Coort, S. L., Hanspers, K., Haw, R., Pico, A. R. & Evelo, C. T., May 2016, In: PLoS computational biology. 12, 5, e1004941.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    23 Scopus citations
  • The reactome pathway knowledgebase

    Fabregat, A., Sidiropoulos, K., Garapati, P., Gillespie, M., Hausmann, K., Haw, R., Jassal, B., Jupe, S., Korninger, F., McKay, S., Matthews, L., May, B., Milacic, M., Rothfels, K., Shamovsky, V., Webber, M., Weiser, J., Williams, M., Wu, G., Stein, L., & 2 othersHermjakob, H. & D'Eustachio, P., 2016, In: Nucleic acids research. 44, D1, p. D481-D487

    Research output: Contribution to journalArticlepeer-review

    Open Access
    874 Scopus citations
  • 2015

    Between pathways and networks lies context: Implications for precision medicine

    Laderas, T., Wu, G. & McWeeney, S., Sep 1 2015, In: Science Progress. 98, 3, p. 253-263 11 p.

    Research output: Contribution to journalArticlepeer-review

  • Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction

    Zhang, S., Chung, W. C., Wu, G., Egan, S. E., Miele, L. & Xu, K., May 15 2015, In: Cancer Research. 75, 10, p. 1936-1943 8 p.

    Research output: Contribution to journalArticlepeer-review

    39 Scopus citations
  • 2014

    A controlled vocabulary for pathway entities and events

    Jupe, S., Jassal, B., Williams, M. & Wu, G., 2014, In: Database. 2014

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Gramene 2013: Comparative plant genomics resources

    Monaco, M. K., Stein, J., Naithani, S., Wei, S., Dharmawardhana, P., Kumari, S., Amarasinghe, V., Youens-Clark, K., Thomason, J., Preece, J., Pasternak, S., Olson, A., Jiao, Y., Lu, Z., Bolser, D., Kerhornou, A., Staines, D., Walts, B., Wu, G., D'Eustachio, P., & 6 othersHaw, R., Croft, D., Kersey, P. J., Stein, L., Jaiswal, P. & Ware, D., Jan 1 2014, In: Nucleic acids research. 42, D1, p. D1193-D1199

    Research output: Contribution to journalArticlepeer-review

    Open Access
    138 Scopus citations
  • Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

    The MAGIC investigators & The GIANT consortium, Aug 7 2014, In: PLoS genetics. 10, 8, e1004517.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    145 Scopus citations
  • ReactomeFIViz: A cytoscape app for pathway and network-based data analysis

    Wu, G., Dawson, E., Duong, A., Haw, R. & Stein, L., Sep 12 2014, In: F1000Research. 3, 4431.2.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    147 Scopus citations
  • The Reactome pathway knowledgebase

    Croft, D., Mundo, A. F., Haw, R., Milacic, M., Weiser, J., Wu, G., Caudy, M., Garapati, P., Gillespie, M., Kamdar, M. R., Jassal, B., Jupe, S., Matthews, L., May, B., Palatnik, S., Rothfels, K., Shamovsky, V., Song, H., Williams, M., Birney, E., & 3 othersHermjakob, H., Stein, L. & D'Eustachio, P., Jan 1 2014, In: Nucleic acids research. 42, D1, p. D472-D477

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1155 Scopus citations
  • Tumor-suppressive activity of lunatic fringe in prostate through differential modulation of notch receptor activation

    Zhang, S., Chung, W. C., Wu, G., Egan, S. E. & Xu, K., Feb 2014, In: Neoplasia (United States). 16, 2, p. 158-167 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    29 Scopus citations
  • 2013

    Systematic MicroRNA Analysis Identifies ATP6V0C as an Essential Host Factor for Human Cytomegalovirus Replication

    Pavelin, J., Reynolds, N., Chiweshe, S., Wu, G., Tiribassi, R. & Grey, F., 2013, In: PLoS pathogens. 9, 12, p. 1-13 13 p., e1003820.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    34 Scopus citations
  • 2012

    A genome-wide association search for type 2 diabetes genes in african americans

    DIAGRAM Consortium, MAGIC Investigators, Anders Hamsten on behalf of Procardis Consortium, DIAGRAM Consortium, GIANT Consortium, Global BPgen Consortium & for the MAGIC investigators, Jan 4 2012, In: PloS one. 7, 1, e29202.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    136 Scopus citations
  • A network module-based method for identifying cancer prognostic signatures

    Wu, G. & Stein, L., 2012, In: Genome biology. 13, 12, p. R112

    Research output: Contribution to journalArticlepeer-review

    Open Access
    116 Scopus citations
  • Annotating cancer variants and anti-cancer therapeutics in Reactome

    Milacic, M., Haw, R., Rothfels, K., Wu, G., Croft, D., Hermjakob, H., D'Eustachio, P. & Stein, L., Dec 2012, In: Cancers. 4, 4, p. 1180-1211 32 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    224 Scopus citations
  • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals

    Dastani, Z., Hivert, M. F., Timpson, N. J., Perry, J. R. B., Yuan, X., Scott, R. A., Henneman, P., Heid, I. M., Kizer, J. R., Lyytikäinen, L. P., Fuchsberger, C., Tanaka, T., Morris, A. P., Small, K., Isaacs, A., Beekman, M., Coassin, S., Lohman, K., Qi, L., Kanoni, S., & 525 othersPankow, J. S., Uh, H. W., Wu, Y., Bidulescu, A., Rasmussen-Torvik, L. J., Greenwood, C. M. T., Ladouceur, M., Grimsby, J., Manning, A. K., Liu, C. T., Kooner, J., Mooser, V. E., Vollenweider, P., Kapur, K. A., Chambers, J., Wareham, N. J., Langenberg, C., Frants, R., Willems-VanDijk, K., Oostra, B. A., Willems, S. M., Lamina, C., Winkler, T. W., Psaty, B. M., Tracy, R. P., Brody, J., Chen, I., Viikari, J., Kähönen, M., Pramstaller, P. P., Evans, D. M., St. Pourcain, B., Sattar, N., Wood, A. R., Bandinelli, S., Carlson, O. D., Egan, J. M., Böhringer, S., van Heemst, D., Kedenko, L., Kristiansson, K., Nuotio, M. L., Loo, B. M., Harris, T., Garcia, M., Kanaya, A., Haun, M., Klopp, N., Wichmann, H. E., Deloukas, P., Katsareli, E., Couper, D. J., Duncan, B. B., Kloppenburg, M., Adair, L. S., Borja, J. B., Florez, J. C., MAGIC Consortium, C., GLGC Investigators, I., MuTHER Consortium, C., Wilson, J. G., Musani, S., Guo, X., Johnson, T., Semple, R., Teslovich, T. M., Redline, S., Buxbaum, S. G., Mohlke, K. L., Meulenbelt, I., Ballantyne, C. M., Dedoussis, G. V., Hu, F. B., Liu, Y., Paulweber, B., Spector, T. D., Slagboom, P. E., Ferrucci, L., Jula, A., Perola, M., Raitakari, O., Salomaa, V., Eriksson, J. G., Frayling, T. M., Hicks, A. A., Lehtimäki, T., Smith, G. D., Siscovick, D. S., Kronenberg, F., van Duijn, C., Loos, R. J. F., Waterworth, D. M., Meigs, J. B., Meigs, J. B., Richards, J. B., Voight, B. F., Scott, L. J., Steinthorsdottir, V., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Hofmann, O. M., Segrè, A. V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Boström, K. B., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Fox, C. S., Franklin, C. S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C. J., Guiducci, C., Hadjadj, S., Hassanali, N., Herder, C., Isomaa, B., Jackson, A. U., Johnson, P. R. V., Jørgensen, T., Kao, W. H. L., Kong, A., Kraft, P., Kuusisto, J., Lauritzen, T., Li, M., Lieverse, A., Lindgren, C. M., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M. A., Narisu, N., Nilsson, P., Owen, K. R., Payne, F., Petersen, A. K., Platou, C., Proenca, C., Prokopenko, I., Rathmann, W., Rayner, N. W., Robertson, N. R., Rocheleau, G., Roden, M., Sampson, M. J., Saxena, R., Shields, B. M., Shrader, P., Sigurdsson, G., Sparsø, T., Strassburger, K., Stringham, H. M., Sun, Q., Swift, A. J., Thorand, B., Tichet, J., Tuomi, T., van Dam, R. M., van Haeften, T. W., van Herpt, T., van Vliet-Ostaptchouk, J. V., Walters, G. B., Weedon, M. N., Wijmenga, C., Witteman, J., Bergman, R. N., Cauchi, S., Gloyn, A. L., Gyllensten, U., Hansen, T., Hide, W. A., Hitman, G. A., Hofman, A., Hunter, D. J., Hveem, K., Laakso, M., Morris, A. D., Palmer, C. N. A., Rudan, I., Sijbrands, E., Stein, L. D., Tuomilehto, J., Uitterlinden, A., Walker, M., Watanabe, R. M., Abecasis, G. R., Boehm, B. O., Campbell, H., Daly, M. J., Hattersley, A. T., Pedersen, O., Barroso, I., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J. F., Illig, T., Froguel, P., van Duijn, C. M., Stefansson, K., Altshuler, D., Boehnke, M., McCarthy, M. I., David, T., Soranzo, N., Wheeler, E., Glazer, N. L., Bouatia-Naji, N., Mägi, R., Randall, J., Elliott, P., Rybin, D., Dehghan, A., Hottenga, J. J., Goel, A., Lajunen, T., Doney, A., Cavalcanti-Proença, C., Kumari, M., Zabena, C., Ingelsson, E., An, P., O'Connell, J., Luan, J., Elliott, A., Roccasecca, R. M., Pattou, F., Sethupathy, P., Ariyurek, Y., Barter, P., Beilby, J. P., Ben-Shlomo, Y., Bergmann, S., Bochud, M., Bonnefond, A., Borch-Johnsen, K., Böttcher, Y., Brunner, E., Bumpstead, S. J., Chen, Y. D. I., Chines, P., Clarke, R., Coin, L. J. M., Cooper, M. N., Song, K., Day, I. N. M., de Geus, E. J. C., Delplanque, J., Fedson, A. C., Fischer-Rosinsky, A., Forouhi, N. G., Franzosi, M. G., Galan, P., Goodarzi, M. O., Graessler, J., Grundy, S., Gwilliam, R., Hallmans, G., Hammond, N., Han, X., Hartikainen, A. L., Hayward, C., Heath, S. C., Hercberg, S., Hillman, D. R., Hingorani, A. D., Hui, J., Hung, J., Kaakinen, M., Kaprio, J., Kesaniemi, Y. A., Kivimaki, M., Knight, B., Koskinen, S., Kovacs, P., Kyvik, K. O., Lathrop, GM., Lawlor, D. A., Bacquer, O. L., Lecoeur, C., Li, Y., Mahley, R., Mangino, M., Martínez-Larrad, M. T., McAteer, J. B., McPherson, R., Meisinger, C., Melzer, D., Meyre, D., Mitchell, B. D., Mukherjee, S., Naitza, S., Neville, M. J., Orrù, M., Pakyz, R., Paolisso, G., Pattaro, C., Pearson, D., Peden, J. F., Pedersen, N. L., Pfeiffer, A. F. H., Pichler, I., Polasek, O., Posthuma, D., Potter, S. C., Pouta, A., Province, M. A., Rice, K., Ripatti, S., Rivadeneira, F., Rolandsson, O., Sandbaek, A., Sandhu, M., Sanna, S., Sayer, A. A., Scheet, P., Seedorf, U., Sharp, S. J., Shields, B., Sigurðsson, G., Sijbrands, E. J. G., Silveira, A., Simpson, L., Singleton, A., Smith, N. L., Sovio, U., Swift, A., Syddall, H., Syvänen, A. C., Tönjes, A., Uitterlinden, A. G., van Dijk, K. W., Varma, D., Visvikis-Siest, S., Vitart, V., Vogelzangs, N., Waeber, G., Wagner, P. J., Walley, A., Walters, GB., Ward, K. L., Watkins, H., Wild, S. H., Willemsen, G., Yarnell, J. W. G., Zelenika, D., Zethelius, B., Zhai, G., Zhao, J. H., Zillikens, M. C., Borecki, I. B., Meneton, P., Magnusson, P. K. E., Nathan, D. M., Williams, G. H., Silander, K., Bornstein, S. R., Schwarz, P., Spranger, J., Karpe, F., Shuldiner, A. R., Cooper, C., Serrano-Ríos, M., Lind, L., Palmer, L. J., Franks, P. W., Marmot, M., Wright, A. F., Stumvoll, M., Hamsten, A., Buchanan, T. A., Valle, T. T., Rotter, J. I., Penninx, B. W. J. H., Boomsma, D. I., Cao, A., Scuteri, A., Schlessinger, D., Uda, M., Ruokonen, A., Jarvelin, M. R., Peltonen, L., Musunuru, K., Pirruccello, J. P., Chasman, D. I., Zee, R. Y. L., O’Donnell, C. J., Ridker, P. M., Koseki, M., Pirruccello, J. P., Johansen, C. T., Fouchier, S. W., Chasman, D. I., Barbalic, M., Ricketts, S. L., Bis, J. C., Feitosa, M. F., Orho-Melander, M., Melander, O., Li, X., Cho, Y. S., Go, M. J., Kim, Y. J., Lee, J. Y., Park, T., Kim, K., Sim, X., Ong, R. T. H., Croteau-Chonka, D. C., Lange, L. A., Smith, J. D., Ziegler, A., Zhang, W., Zee, R. Y. L., Witteman, J. C. M., Whitfield, J. B., Thompson, J. R., Surakka, I., Smit, J. H., Sinisalo, J., Scott, J., Saharinen, J., Sabatti, C., Rose, L. M., Roberts, R., Rieder, M., Parker, A. N., Pare, G., O’Donnell, C. J., Nieminen, M. S., Nickerson, D. A., Montgomery, G. W., McArdle, W., Masson, D., Martin, N. G., Marroni, F., Lucas, G., Luben, R., Lokki, M. L., Lettre, G., Launer, L. J., Lakatta, E. G., Laaksonen, R., König, I. R., Khaw, K. T., Kaplan, L. M., Johansson, Å., Janssens, A. C. W., Igl, W., Hovingh, G. K., Hengstenberg, C., Havulinna, A. S., Hastie, N. D., Harris, T. B., Haritunians, T., Hall, A. S., Groop, L. C., Gonzalez, E., Freimer, N. B., Erdmann, J., Ejebe, K. G., Döring, A., Dominiczak, A. F., Demissie, S., de Faire, U., Caulfield, M. J., Boekholdt, S. M., Assimes, T. L., Quertermous, T., Seielstad, M., Wong, T. Y., Tai, E. S., Feranil, A. B., Kuzawa, C. W., Gabriel, S. B., Holm, H., Gudnason, V., Taylor, H. A., Krauss, R. M., Ordovas, J. M., Kooner, J. S., Tall, A. R., Hegele, R. A., Kastelein, J. J. P., Schadt, E. E., Strachan, D. P., Reilly, M. P., Samani, N. J., Schunkert, H., Cupples, L. A., Sandhu, M. S. & Munroe, P. B., Mar 29 2012, In: PLoS genetics. 8, 3, e1002607.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    326 Scopus citations
  • 2011

    Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1

    Bown, M. J., Jones, G. T., Harrison, S. C., Wright, B. J., Bumpstead, S., Baas, A. F., Gretarsdottir, S., Badger, S. A., Bradley, D. T., Burnand, K., Child, A. H., Clough, R. E., Cockerill, G., Hafez, H., Scott, D. J. A., Futers, S., Johnson, A., Sohrabi, S., Smith, A., Thompson, M. M., & 462 othersvan Bockxmeer, F. M., Waltham, M., Matthiasson, S. E., Thorleifsson, G., Thorsteinsdottir, U., Blankensteijn, J. D., Teijink, J. A. W., Wijmenga, C., de Graaf, J., Kiemeney, L. A., Assimes, T. L., McPherson, R., Folkersen, L., Franco-Cereceda, A., Palmen, J., Smith, A. J., Sylvius, N., Wild, J. B., Refstrup, M., Edkins, S., Gwilliam, R., Hunt, S. E., Potter, S., Lindholt, J. S., Frikke-Schmidt, R., Tybjærg-Hansen, A., Hughes, A. E., Golledge, J., Norman, P. E., van Rij, A., Powell, J. T., Eriksson, P., Stefansson, K., Thompson, J. R., Humphries, S. E., Sayers, R. D., Deloukas, P., Samani, N. J., Schunkert, H., König, I. R., Kathiresan, S., Reilly, M. P., Holm, H., Preuss, M., Stewart, A. F. R., Barbalic, M., Gieger, C., Absher, D., Aherrahrou, Z., Allayee, H., Altshuler, D., Anand, S. S., Andersen, K., Anderson, J. L., Ardissino, D., Ball, S. G., Balmforth, A. J., Barnes, T. A., Becker, D. M., Becker, L. C., Berger, K., Bis, J. C., Matthijs Boekholdt, S., Boerwinkle, E., Braund, P. S., Susan Burnett, M., Buysschaert, I., Carlquist, J. F., Chen, L., Cichon, S., Codd, V., Davies, R. W., Dedoussis, G., Dehghan, A., Demissie, S., Devaney, J. M., Diemert, P., Do, R., Doering, A., Eifert, S., El Mokhtari, N. E., Ellis, S. G., Elosua, R., Engert, J. C., Epstein, S. E., de Faire, U., Fischer, M., Folsom, A. R., Freyer, J., Gigante, B., Girelli, D., Gudnason, V., Gulcher, J. R., Halperin, E., Hammond, N., Hazen, S. L., Hofman, A., Horne, B. D., Illig, T., Iribarren, C., Wouter Jukema, J., Kaiser, M. A., Kaplan, L. M., Kastelein, J. J. P., Khaw, K. T., Knowles, J. W., Kolovou, G., Kong, A., Laaksonen, R., Lambrechts, D., Leander, K., Lettre, G., Li, M., Lieb, W., Loley, C., Lotery, A. J., Mannucci, P. M., Maouche, S., Martinelli, N., McKeown, P. P., Meisinger, C., Meitinger, T., Melander, O., Angelica Merlini, P., Mooser, V., Morgan, T., Mühleisen, T. W., Muhlestein, J. B., Münzel, T., Musunuru, K., Nahrstaedt, J., Nelson, C. P., Nöthen, M. M., Olivieri, O., Patel, R. S., Patterson, C. C., Peters, A., Peyvandi, F., Qu, L., Quyyumi, A. A., Rader, D. J., Rallidis, L. S., Rice, C., Rosendaal, F. R., Rubin, D., Salomaa, V., Lourdes Sampietro, M., Sandhu, M. S., Schadt, E., Schäfer, A., Schillert, A., Schreiber, S., Schrezenmeir, J., Schwartz, S. M., Siscovick, D. S., Sivananthan, M., Sivapalaratnam, S., Smith, T. B., Snoep, J. D., Soranzo, N., Spertus, J. A., Stark, K., Stirrups, K., Stoll, M., Wilson Tang, W. H., Tennstedt, S., Thorgeirsson, G., Tomaszewski, M., Uitterlinden, A. G., van Rij, A. M., Voight, B. F., Wareham, N. J., Wells, G. A., Wichmann, H. E., Wild, P. S., Willenborg, C., Witteman, J. C. M., Ye, S., Zeller, T., Ziegler, A., Cambien, F., Goodall, A. H., Adrienne Cupples, L., Quertermous, T., März, W., Hengstenberg, C., Blankenberg, S., Ouwehand, W. H., Hall, A. S., Roberts, R., O'Donnell, C. J., Erdmann, J., Newton-Cheh, C., Johnson, T., Gateva, V., Tobin, M. D., Bochud, M., Coin, L., Najjar, S. S., Hua Zhao, J., Heath, S. C., Eyheramendy, S., Papadakis, K., Scott, L. J., Zhang, F., Farrall, M., Tanaka, T., Wallace, C., Chambers, J. C., Nilsson, P., van der Harst, P., Polidoro, S., Grobbee, D. E., Onland-Moret, N. C., Bots, M. L., Wain, L. V., Elliott, K. S., Teumer, A., Luan, J., Lucas, G., Kuusisto, J., Burton, P. R., Hadley, D., McArdle, W. L., Brown, M., Dominiczak, A., Newhouse, S. J., Webster, J., Zeggini, E., Beckmann, J. S., Lim, N., Song, K., Vollenweider, P., Waeber, G., Waterworth, D. M., Yuan, X., Groop, L., Orho-Melander, M., Allione, A., Di Gregorio, A., Guarrera, S., Panico, S., Ricceri, F., Romanazzi, V., Sacerdote, C., Vineis, P., Barroso, I., Luben, R. N., Crawford, G. J., Jousilahti, P., Perola, M., Boehnke, M., Bonnycastle, L. L., Jackson, A. U., Mohlke, K. L., Stringham, H. M., Valle, T. T., Willer, C. J., Bergman, R. N., Morken, M. A., Döring, A., Org, E., Pfeufer, A., Marrugat, J., Subirana, I., Freimer, N. B., Hartikainen, A. L., McCarthy, M. I., O'Reilly, P. F., Peltonen, L., Pouta, A., de Jong, P. E., Snieder, H., van Gilst, W. H., Clarke, R., Goel, A., Hamsten, A., Peden, J. F., Seedorf, U., Syvänen, A. C., Tognoni, G., Lakatta, E. G., Sanna, S., Scheet, P., Schlessinger, D., Scuteri, A., Dörr, M., Ernst, F., Felix, S. B., Homuth, G., Lorbeer, R., Reffelmann, T., Rettig, R., Völker, U., Galan, P., Gut, I. G., Hercberg, S., Mark Lathrop, G., Zelenika, D., Williams, F. M., Zhai, G., Laakso, M., Forouhi, N. G., Völzke, H., Uiterwaal, C. S., van der Schouw, Y. T., Numans, M. E., Matullo, G., Navis, G., Berglund, G., Bingham, S. A., Kooner, J. S., Connell, J. M., Bandinelli, S., Ferrucci, L., Watkins, H., Spector, T. D., Tuomilehto, J., Strachan, D. P., Laan, M., Meneton, P., Uda, M., Jarvelin, M. R., Loos, R. J. F., Elliott, P., Abecasis, G. R., Caulfield, M., Munroe, P. B., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Huth, C., Aulchenko, Y. S., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., Hofmann, O. M., Dupuis, J., Qi, L., Segrè, A. V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Bengtsson Boström, K., Bravenboer, B., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, A. L., Elliott, A. L., Erdos, M. R., Fox, C. S., Franklin, C. S., Ganser, M., Grarup, N., Green, T., Griffin, S., Groves, C. J., Guiducci, C., Hadjadj, S., Hassanali, N., Herder, C., Isomaa, B., Johnson, P. R. V., Jørgensen, T., Kao, W. H. L., Klopp, N., Kraft, P., Lauritzen, T., Lieverse, A., Lindgren, C. M., Lyssenko, V., Marre, M., Midthjell, K., Narisu, N., Owen, K. R., Payne, F., Perry, J. R. B., Petersen, A. K., Platou, C., Proença, C., Prokopenko, I., Rathmann, W., William Rayner, N., Robertson, N. R., Rocheleau, G., Roden, M., Sampson, M. J., Saxena, R., Shields, B. M., Shrader, P., Sigurdsson, G., Sparsø, T., Strassburger, K., Sun, Q., Swift, A. J., Thorand, B., Tichet, J., Tuomi, T., van Dam, R. M., van Haeften, T. W., van Herpt, T., van Vliet-Ostaptchouk, J. V., Bragi Walters, G., Weedon, M. N., Cauchi, S., Gloyn, A. L., Gyllensten, U., Hansen, T., Hide, W. A., Hitman, G. A., Hunter, D. J., Hveem, K., Morris, A. D., Palmer, C. N. A., Pramstaller, P. P., Rudan, I., Sijbrands, E., Stein, L. D., Uitterlinden, A., Walker, M., Watanabe, R. M., Boehm, B. O., Campbell, H., Daly, M. J., Hattersley, A. T., Hu, F. B., Meigs, J. B., Pankow, J. S., Pedersen, O., Florez, J. C., Frayling, T. M., Sladek, R., Wilson, J. F., Froguel, P., van Duijn, C. M., Blair, R. D., Hill, A. A., Gerry Hill, B., Lewis, D. R., McNoe, L. A., Merriman, T. R., Naik, D. K., Vicky Phillips, L., Thomson, I. A., Topless, R., Vasudevan, T. M. & Yu, G., Nov 11 2011, In: American Journal of Human Genetics. 89, 5, p. 619-627 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    138 Scopus citations
  • Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

    Strawbridge, R. J., Dupuis, J., Prokopenko, I., Barker, A., Ahlqvist, E., Rybin, D., Petrie, J. R., Travers, M. E., Bouatia-Naji, N., Dimas, A. S., Nica, A. C., Wheeler, E., Chen, H., Voight, B. F., Taneera, J., Kanoni, S., Peden, J. F., Turrini, F., Gustafsson, S., Zabena, C., & 671 othersAlmgren, P., Barker, D. J. P., Barnes, D., Dennison, E. M., Eriksson, J. G., Eriksson, P., Eury, E., Folkersen, L., Fox, C. S., Frayling, T. M., Goel, A., Gu, H. F., Horikoshi, M., Isomaa, B., Jackson, A. U., Jameson, K. A., Kajantie, E., Kerr-Conte, J., Kuulasmaa, T., Kuusisto, J., Loos, R. J. F., Luan, J., Makrilakis, K., Manning, A. K., Martínez-Larrad, M. T., Narisu, N., Mannila, M. N., Öhrvik, J., Osmond, C., Pascoe, L., Payne, F., Sayer, A. A., Sennblad, B., Silveira, A., Stančcáková, A., Stirrups, K., Swift, A. J., Syvänen, A. C., Tuomi, T., Van't Hooft, F. M., Walker, M., Weedon, M. N., Xie, W., Zethelius, B., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., Mcculloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Hofmann, O. M., Qi, L., Segre, A. V., Van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Bostrom, K. B., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Franklin, C. S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C. J., Guiducci, C., Hadjadj, S., Hassanali, N., Herder, C., Johnson, P. R. V., Jorgensen, T., Kao, W. H. L., Klopp, N., Kong, A., Kraft, P., Lauritzen, T., Li, M., Lieverse, A., Lindgren, C. M., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M. A., Nilsson, P., Owen, K. R., Perry, J. R. B., Petersen, A. K., Platou, C., Proenca, C., Rathmann, W., Rayner, N. W., Robertson, N. R., Rocheleau, G., Roden, M., Sampson, M. J., Saxena, R., Shields, B. M., Shrader, P., Sigurdsson, G., Sparso, T., Strassburger, K., Stringham, H. M., Sun, Q., Thorand, B., Tichet, J., Van Dam, R. M., Van Haeften, T. W., Van Herpt, T., Van Vliet-Ostaptchouk, J. V., Walters, G. B., Wijmenga, C., Witteman, J. C. M., Bergman, R. N., Cauchi, S., Collins, F. S., Gloyn, A. L., Gyllensten, U., Hansen, T., Hide, W. A., Hitman, G. A., Hofman, A., Hunter, D. J., Hveem, K., Laakso, M., Mohlke, K. L., Morris, A. D., Palmer, C. N. A., Pramstaller, P. P., Rudan, I., Sijbrands, E., Stein, L. D., Tuomilehto, J., Uitterlinden, A. G., Wareham, N. J., Watanabe, R. M., Abecasis, G. R., Boehm, B. O., Campbell, H., Daly, M. J., Hattersley, A. T., Hu, F. B., Meigs, J. B., Pankow, J. S., Pedersen, O., Wichmann, H. E., Barroso, I., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J. F., Illig, T., Froguel, P., Van Duijn, C. M., Stefansson, K., Altshuler, D., Boehnke, M., McCarthy, M. I., Speliotes, E. K., Berndt, S. I., Monda, K. L., Allen, H. L., Magi, R., Randall, J. C., Vedantam, S., Winkler, T. W., Workalemahu, T., Heid, I. M., Wood, A. R., Weyant, R. J., Estrada, K., Liang, L., Nemesh, J., Park, J. H., Kilpelainen, T. O., Yang, J., Esko, T., Feitosa, M. F., Kutalik, Z., Mangino, M., Scherag, A., Smith, A. V., Zhao, J. H., Aben, K. K., Absher, D. M., Dixon, A. L., Fisher, E., Glazer, N. L., Goddard, M. E., Heard-Costa, N. L., Hoesel, V., Hottenga, J. J., Johansson, A., Johnson, T., Ketkar, S., Lamina, C., Li, S., Moffatt, M. F., Myers, R. H., Peters, M. J., Preuss, M., Ripatti, S., Rivadeneira, F., Sandholt, C., Timpson, N. J., Tyrer, J. P., Van Wingerden, S., White, C. C., Wiklund, F., Barlassina, C., Chasman, D. I., Cooper, M. N., Jansson, J. O., Lawrence, R. W., Pellikka, N., Shi, J., Thiering, E., Alavere, H., Alibrandi, M. T. S., Arnold, A. M., Aspelund, T., Atwood, L. D., Balmforth, A. J., Ben-Shlomo, Y., Bergmann, S., Biebermann, H., Blakemore, A. I. F., Boes, T., Bornstein, S. R., Brown, M. J., Buchanan, T. A., Busonero, F., Cappuccio, F. P., Cavalcanti-Proenca, C., Chen, Y. D. I., Chen, C. M., Clarke, R., Coin, L., Connell, J., Day, I. N. M., Den Heijer, M., Duan, J., Ebrahim, S., Elliott, P., Elosua, R., Eiriksdottir, G., Facheris, M. F., Felix, S. B., Fischer-Posovszky, P., Folsom, A. R., Friedrich, N., Freimer, N. B., Fu, M., Gaget, S., Gejman, P. V., Geus, E. J. C., Gjesing, A. P., Goyette, P., Grasler, J., Greenawalt, D. M., Gudnason, V., Hartikainen, A. L., Hall, A. S., Havulinna, A. S., Hayward, C., Heath, A. C., Hengstenberg, C., Hicks, A. A., Hinney, A., Homuth, G., Hui, J., Igl, W., Iribarren, C., Jacobs, K. B., Jarick, I., Jewell, E., John, U., Jousilahti, P., Jula, A., Kaakinen, M., Kaplan, L. M., Kathiresan, S., Kettunen, J., Kinnunen, L., Knowles, J. W., Kolcic, I., König, I. R., Koskinen, S., Kovacs, P., Kvaloy, K., Laitinen, J., Lantieri, O., Lanzani, C., Launer, L. J., Lecoeur, C., Lehtimaki, T., Lettre, G., Liu, J., Lokki, M. L., Lorentzon, M., Luben, R. N., Ludwig, B., Manunta, P., Marek, D., Martin, N. G., McArdle, W. L., McCarthy, A., McKnight, B., Melander, O., Meyre, D., Montgomery, G. W., Mulic, R., Ngwa, J. S., Nelis, M., Neville, M. J., Nyholt, D. R., O'Donnell, C. J., O'Rahilly, S., Ong, K. K., Oostra, B., Pare, G., Parker, A. N., Perola, M., Pichler, I., Pietilainen, K. H., Platou, C. G. P., Polasek, O., Pouta, A., Rafelt, S., Raitakari, O., Rayner, N. W., Ridderstrale, M., Rief, W., Ruokonen, A., Rzehak, P., Salomaa, V., Sanders, A. R., Sandhu, M. S., Sanna, S., Saramies, J., Savolainen, M. J., Scherag, S., Schipf, S., Schreiber, S., Schunkert, H., Silander, K., Sinisalo, J., Siscovick, D. S., Smit, J. H., Soranzo, N., Sovio, U., Stephens, J., Surakka, I., Tammesoo, M. L., Tardif, J. C., Teder-Laving, M., Teslovich, T. M., Thompson, J. R., Thomson, B., Tonjes, A., Van Meurs, J. B. J., Van Ommen, G. J., Vatin, V., Viikari, J., Visvikis-Siest, S., Vitart, V., Vogel, C. I. G., Waite, L. L., Wallaschofski, H., Widen, E., Wiegand, S., Wild, S. H., Willemsen, G., Witte, D. R., Xu, J., Zhang, Q., Zgaga, L., Ziegler, A., Zitting, P., Beilby, J. P., Farooqi, I. S., Hebebrand, J., Huikuri, H. V., James, A. L., Kahonen, M., Levinson, D. F., Macciardi, F., Nieminen, M. S., Ohlsson, C., Palmer, L. J., Ridker, P. M., Stumvoll, M., Beckmann, J. S., Boeing, H., Boomsma, D. I., Caulfield, M. J., Chanock, S. J., Cupples, L. A., Smith, G. D., Erdmann, J., Gronberg, H., Hall, P., Harris, T. B., Hayes, R. B., Heinrich, J., Jarvelin, M. R., Kaprio, J., Karpe, F., Khaw, K. T., Kiemeney, L. A., Krude, H., Lawlor, D. A., Metspalu, A., Munroe, P. B., Ouwehand, W. H., Penninx, B. W., Peters, A., Quertermous, T., Reinehr, T., Rissanen, A., Samani, N. J., Schwarz, P. E. H., Shuldiner, A. R., Spector, T. D., Uda, M., Valle, T. T., Wabitsch, M., Waeber, G., Watkins, H., Wright, A. F., Zillikens, M. C., Chatterjee, N., Purcell, S., Schadt, E. E., Visscher, P. M., Assimes, T. L., Borecki, I. B., Deloukas, P., Haritunians, T., Kaplan, R. C., O'Connell, J. R., Peltonen, L., Schlessinger, D., Strachan, D. P., North, K. E., Hirschhorn, J. N., Ingelsson, E., Parts, L., Glass, D., Nisbet, J., Barrett, A., Sekowska, M., Potter, S., Grundberg, E., Small, K., Hedman, A. K., Bataille, V., Bell, J. T., Surdulescu, G., Ingle, C., Nestle, F. O., Di Meglio, P., Min, J. L., Wilk, A., Hammond, C. J., Yang, T. P., Montgomery, S. B., Zondervan, K. T., Durbin, R., Ahmadi, K., Dermitzakis, E. T., Reilly, M. P., Holm, H., Stewart, A. F. R., Barbalic, M., Aherrahrou, Z., Allayee, H., Anand, S. S., Andersen, K., Anderson, J. L., Ardissino, D., Ball, S. G., Barnes, T. A., Becker, D. M., Becker, L. C., Berger, K., Bis, J. C., Boekholdt, S. M., Braund, P. S., Burnett, M. S., Buysschaert, I., Carlquist, J. F., Chen, L., Codd, V., Davies, R. W., Cichon, S., Dedoussis, G. V., Demissie, S., Dehghan, A., Devaney, J. M., Diemert, P., Do, R., Doering, A., Eifert, S., El Mokhtari, N. E., Ellis, S. G., Engert, J. C., Epstein, S. E., De Faire, U., Fischer, M., Freyer, J., Gigante, B., Girelli, D., Gretarsdottir, S., Gulcher, J. R., Halperin, E., Hammond, N., Hazen, S. L., Horne, B. D., Jones, G. T., Jukema, J. W., Kaiser, M. A., Kastelein, J. J. P., Kolovou, G., Laaksonen, R., Lambrechts, D., Leander, K., Li, M., Lieb, W., Loley, C., Lotery, A. J., Mannucci, P. M., Maouche, S., Martinelli, N., McKeown, P. P., Meisinger, C., Merlini, P. A., Mooser, V., Morgan, T., Mühleisen, T. W., Muhlestein, J. B., Münzel, T., Musunuru, K., Nahrstaedt, J., Nelson, C. P., Nöthen, M. M., Olivieri, O., Patel, R. S., Patterson, C. C., Peyvandi, F., Qu, L., Quyyumi, A. A., Rader, D. J., Rallidis, L. S., Rice, C., Rosendaal, F. R., Rubin, D., Sampietro, M. L., Sandhu, M. S., Schadt, E., Schäfer, A., Schillert, A., Schrezenmeir, J., Schwartz, S. M., Sivananthan, M., Sivapalaratnam, S., Smith, T. B., Snoep, J. D., Spertus, J. A., Stark, K., Stoll, M., Wilson Tang, W. H., Tennstedt, S., Thorgeirsson, G., Tomaszewski, M., Van Rij, A. M., Wells, G. A., Wild, P. S., Willenborg, C., Wright, B. J., Ye, S., Zeller, T., Cambien, F., Goodall, A. H., Marz, W., Blankenberg, S., Roberts, R., McPherson, R., Hopewell, J. C., Parish, S., Offer, A., Bowman, L., Sleight, P., Armitage, J., Peto, R., Collins, R., Chambers, J. C., Ahmed, N., Donnelly, P., Kooner, A. S., Scott, J., Sehmi, J., Zhang, W., Kooner, J., Sabater-Lleal, M., Mälarstig, A., Hellénius, M. L., Olsson, G., Rust, S., Assmann, G., Seedorf, U., Barlera, S., Tognoni, G., Franzosi, M. G., Linksted, P., Ongen, H., Kyriakou, T., Green, F., Farrall, M., Saleheen, D., Rasheed, A., Zaidi, M., Shah, N., Samuel, M., Mallick, N., Azhar, M., Zaman, K., Samad, A., Ishaq, M., Gardezi, A., Memon, F. U. R., Frossard, P., Danesh, J., Östenson, C. G., Lind, L., Cooper, C. C., Serrano-Ríos, M., Ferrannini, E., Forsen, T. J., Pattou, F., Langenberg, C., Hamsten, A. & Florez, J. C., Oct 1 2011, In: Diabetes. 60, 10, p. 2624-2634 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    268 Scopus citations
  • Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening

    Sawey, E. T., Chanrion, M., Cai, C., Wu, G., Zhang, J., Zender, L., Zhao, A., Busuttil, R. W., Yee, H., Stein, L., French, D. M., Finn, R. S., Lowe, S. W. & Powers, S., Mar 8 2011, In: Cancer Cell. 19, 3, p. 347-358 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    313 Scopus citations
  • Reactome: A database of reactions, pathways and biological processes

    Croft, D., O'Kelly, G., Wu, G., Haw, R., Gillespie, M., Matthews, L., Caudy, M., Garapati, P., Gopinath, G., Jassal, B., Jupe, S., Kalatskaya, I., MayMahajan, S., May, B., Ndegwa, N., Schmidt, E., Shamovsky, V., Yung, C., Birney, E., Hermjakob, H., & 2 othersD'Eustachio, P. & Stein, L., Jan 2011, In: Nucleic acids research. 39, SUPPL. 1, p. D691-D697

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1106 Scopus citations
  • 2010

    A human functional protein interaction network and its application to cancer data analysis

    Wu, G., Feng, X. & Stein, L., May 19 2010, In: Genome biology. 11, 5, R53.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    458 Scopus citations
  • A viral microRNA down-regulates multiple cell cycle genes through mRNA 59′UTRs

    Grey, F., Tirabassi, R., Meyers, H., Wu, G., McWeeney, S., Hook, L. & Nelson, J. A., Jun 2010, In: PLoS pathogens. 6, 6

    Research output: Contribution to journalArticlepeer-review

    Open Access
    169 Scopus citations
  • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., Hofmann, O. M., & 138 othersDupuis, J., Qi, L., Segrè, A. V., Van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Boström, K. B., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Fox, C. S., Franklin, C. S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C. J., Guiducci, C., Hadjadj, S., Hassanali, N., Herder, C., Isomaa, B., Jackson, A. U., Johnson, P. R. V., Jørgensen, T., Kao, W. H. L., Klopp, N., Kong, A., Kraft, P., Kuusisto, J., Lauritzen, T., Li, M., Lieverse, A., Lindgren, C. M., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M. A., Narisu, N., Nilsson, P., Owen, K. R., Payne, F., Perry, J. R. B., Petersen, A. K., Platou, C., Proença, C., Prokopenko, I., Rathmann, W., Rayner, N. W., Robertson, N. R., Rocheleau, G., Roden, M., Sampson, M. J., Saxena, R., Shields, B. M., Shrader, P., Sigurdsson, G., Sparsø, T., Strassburger, K., Stringham, H. M., Sun, Q., Swift, A. J., Thorand, B., Tichet, J., Tuomi, T., Van Dam, R. M., Van Haeften, T. W., Van Herpt, T., Van Vliet-Ostaptchouk, J. V., Walters, G. B., Weedon, M. N., Wijmenga, C., Witteman, J., Bergman, R. N., Cauchi, S., Collins, F. S., Gloyn, A. L., Gyllensten, U., Hansen, T., Hide, W. A., Hitman, G. A., Hofman, A., Hunter, D. J., Hveem, K., Laakso, M., Mohlke, K. L., Morris, A. D., Palmer, C. N. A., Pramstaller, P. P., Rudan, I., Sijbrands, E., Stein, L. D., Tuomilehto, J., Uitterlinden, A., Walker, M., Wareham, N. J., Watanabe, R. M., Abecasis, G. R., Boehm, B. O., Campbell, H., Daly, M. J., Hattersley, A. T., Hu, F. B., Meigs, J. B., Pankow, J. S., Pedersen, O., Wichmann, H. E., Barroso, I., Florez, J. C., Frayling, T. M., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J. F., Illig, T., Froguel, P., Van Duijn, C. M., Stefansson, K., Altshuler, D., Boehnke, M. & McCarthy, M. I., Jul 2010, In: Nature genetics. 42, 7, p. 579-589 11 p.

    Research output: Contribution to journalArticlepeer-review

    1412 Scopus citations
  • 2009

    Reactome knowledgebase of human biological pathways and processes

    Matthews, L., Gopinath, G., Gillespie, M., Caudy, M., Croft, D., de Bono, B., Garapati, P., Hemish, J., Hermjakob, H., Jassal, B., Kanapin, A., Lewis, S., Mahajan, S., May, B., Schmidt, E., Vastrik, I., Wu, G., Birney, E., Stein, L. & D'eustachio, P., 2009, In: Nucleic acids research. 37, SUPPL. 1, p. D619-D622

    Research output: Contribution to journalArticlepeer-review

    Open Access
    661 Scopus citations
  • 2007

    Reactome: A knowledge base of biologic pathways and processes

    Vastrik, I., D'Eustachio, P., Schmidt, E., Joshi-Tope, G., Gopinath, G., Croft, D., de Bono, B., Gillespie, M., Jassal, B., Lewis, S., Matthews, L., Wu, G., Birney, E. & Stein, L., Mar 16 2007, In: Genome biology. 8, 3, R39.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    475 Scopus citations
  • 2005

    Reactome: A knowledgebase of biological pathways

    Joshi-Tope, G., Gillespie, M., Vastrik, I., D'Eustachio, P., Schmidt, E., de Bono, B., Jassal, B., Gopinath, G. R., Wu, G. R., Matthews, L., Lewis, S., Birney, E. & Stein, L., Jan 1 2005, In: Nucleic acids research. 33, DATABASE ISS., p. D428-D432

    Research output: Contribution to journalArticlepeer-review

    Open Access
    977 Scopus citations
  • 2003

    The genome knowledgebase: A resource for biologists and bioinformaticists

    Joshi-Tope, G., Vastrik, I., Gopinath, G. R., Matthews, L., Schmidt, E., Gillespie, M., D'Eustachio, P., Jassal, B., Lewis, S., Wu, G., Birney, E. & Stein, L., 2003, In: Cold Spring Harbor symposia on quantitative biology. 68, p. 237-243 7 p.

    Research output: Contribution to journalArticlepeer-review

    43 Scopus citations