Grover Bagby

Professor Emeritus

  • 5106 Citations
  • 42 h-Index
1966 …2015

Research output per year

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Research Output

2015

Oxymetholone therapy of fanconi anemia suppresses osteopontin transcription and induces hematopoietic stem cell cycling

Zhang, Q. S., Benedetti, E., Deater, M., Schubert, K., Major, A., Pelz, C., Impey, S., Marquez-Loza, L., Rathbun, R. K., Kato, S., Bagby, G. C. & Grompe, M., Jan 13 2015, In : Stem Cell Reports. 4, 1, p. 90-102 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

P38 mitogen-activated protein kinase inhibition enhances invitro erythropoiesis of Fanconi anemia, complementation group A-deficient bonemarrow cells

Svahn, J., Lanza, T., Rathbun, K., Bagby, G., Ravera, S., Corsolini, F., Pistorio, A., Longoni, D., Farruggia, P., Dufour, C. & Cappelli, E., Apr 1 2015, In : Experimental hematology. 43, 4, p. 295-299 5 p.

Research output: Contribution to journalArticle

7 Scopus citations
2013

FANCA and FANCC modulate TLR and p38 MAPK-dependent expression of IL-1β in macrophages

Garbati, M. R., Hays, L. E., Keeble, W., Yates, J. E., Rathbun, R. K. & Bagby, G. C., Jan 1 2013, In : Blood. 122, 18, p. 3197-3205 9 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

The PI3K/Akt1 pathway enhances steady-state levels of FANCL

Dao, K. H. T., Rotelli, M. D., Brown, B. R., Yates, J. E., Rantala, J., Tognon, C., Tyner, J. W., Druker, B. J. & Bagby, G. C., Aug 15 2013, In : Molecular biology of the cell. 24, 16, p. 2582-2592 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2012

FANCL ubiquitinates β-catenin and enhances its nuclear function

Dao, K. H. T., Rotelli, M. D., Petersen, C. L., Kaech, S., Nelson, W. D., Yates, J. E., Hanlon Newell, A. E., Olson, S. B., Druker, B. J. & Bagby, G. C., Jul 12 2012, In : Blood. 120, 2, p. 323-334 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

Immune response gene profiles in the term placenta depend upon maternal muscle mass

O'Tierney, P. F., Lewis, R. M., McWeeney, S. K., Hanson, M. A., Inskip, H. M., Morgan, T. K., Barker, D. J., Bagby, G., Cooper, C., Godfrey, K. M. & Thornburg, K. L., Oct 1 2012, In : Reproductive Sciences. 19, 10, p. 1041-1056 16 p.

Research output: Contribution to journalArticle

13 Scopus citations

p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC and FANCA-deficient mononuclear phagocytes

Anur, P., Yates, J., Garbati, M. R., Vanderwerf, S., Keeble, W., Rathbun, K., Hays, L. E., Tyner, J. W., Svahn, J., Cappelli, E., Dufour, C. & Bagby, G. C., Mar 1 2012, In : Blood. 119, 9, p. 1992-2002 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

The fate of granulosa cells following premature oocyte loss and the development of ovarian cancers

Pitman, J. L., McNeilly, A. S., McNeilly, J. R., Hays, L. E., Bagby, G. C., Sawyer, H. R. & McNatty, K. P., Dec 1 2012, In : International Journal of Developmental Biology. 56, 10-12, p. 949-958 10 p.

Research output: Contribution to journalArticle

8 Scopus citations
2011

Aplastic Anemia and Related Bone Marrow Failure States

Bagby, G. C., Jul 1 2011, Goldman's Cecil Medicine: Twenty Fourth Edition. Elsevier Inc., Vol. 1. p. 1083-1090 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

The stem cell fitness landscape and pathways of molecular leukemogenesis

Bagby, G. C. & Fleischman, A. G., Jan 1 2011, In : Frontiers in Bioscience - Scholar. 3 S, 2, p. 487-500 14 p.

Research output: Contribution to journalReview article

14 Scopus citations

TNFα facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms

Fleischman, A. G., Aichberger, K. J., Luty, S. B., Bumm, T. G., Petersen, C. L., Doratotaj, S., Vasudevan, K. B., LaTocha, D. H., Yang, F., Press, R. D., Loriaux, M. M., Pahl, H. L., Silver, R. T., Agarwal, A., O'Hare, T., Druker, B. J., Bagby, G. C. & Deininger, M. W., Dec 8 2011, In : Blood. 118, 24, p. 6392-6398 7 p.

Research output: Contribution to journalArticle

124 Scopus citations
2010

Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol

Zhang, Q. S., Marquez-Loza, L., Eaton, L., Duncan, A. W., Goldman, D. C., Anur, P., Watanabe-Smith, K., Rathbun, R. K., Fleming, W. H., Bagby, G. C. & Grompe, M., Dec 9 2010, In : Blood. 116, 24, p. 5140-5148 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia

Pulliam-Leath, A. C., Ciccone, S. L., Nalepa, G., Li, X., Si, Y., Miravalle, L., Smith, D., Yuan, J., Li, J., Anur, P., Orazi, A., Vance, G. H., Yang, F. C., Hanenberg, H., Bagby, G. C. & Clapp, D. W., Oct 21 2010, In : Blood. 116, 16, p. 2915-2920 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

Human FANCC is hypomorphic in murine Fancc-deficient cells

Hays, L. E., Keeble, W. W., Yates, J. E., Rathbun, R. K., Koretsky, T., Olson, S. B., Sun, Z., Clapp, D. W. & Bagby, G. C., Sep 23 2010, In : Blood. 116, 12, p. 2057-2060 4 p.

Research output: Contribution to journalArticle

7 Scopus citations
2009

Expression profiling of the ovarian surface kinome reveals candidate genes for early neoplastic changes

Pejovic, T., Pande, N. T., Mori, M., Mhawech-Fauceglia, P., Harrington, C., Mongoue-Tchokote, S., Dim, D., Andrews, C., Beck, A., Tarumi, Y., Djilas, J., Cappuccini, F., Caballero, O., Huang, J., Levy, S., Tsiamouri, A., Cain, J., Bagby, G. C., Strausberg, R. L., Simpson, A. J. & 1 others, Odunsi, K. O., Jan 1 2009, In : Translational Oncology. 2, 4, p. 341-349 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Introducing "e-Blood"

Bagby, G. C. & Dunbar, C. E., Nov 17 2009, In : Blood. 113, 19, 1 p.

Research output: Contribution to journalEditorial

14 Scopus citations

Preface

Bagby, G. C. & Meyers, G., Apr 1 2009, In : Hematology/Oncology Clinics of North America. 23, 2, p. xiii-xiv

Research output: Contribution to journalEditorial

2 Scopus citations

TLR8-dependent TNF-α overexpression in Fanconi anemia group C cells

Vanderwerf, S. M., Svahn, J., Olson, S., Rathbun, R. K., Harrington, C., Yates, J., Keeble, W., Anderson, D. C., Anur, P., Pereira, N. F., Pilonetto, D. V., Pasquini, R. & Bagby, G. C., Dec 17 2009, In : Blood. 114, 26, p. 5290-5298 9 p.

Research output: Contribution to journalArticle

51 Scopus citations
2008

Cigarette smoke induces genetic instability in airway epithelial cells by suppressing FANCD2 expression

Hays, L. E., Zodrow, D. M., Yates, J. E., Deffebach, M. E., Jacoby, D. B., Olson, S. B., Pankow, J. F. & Bagby, G. C., May 20 2008, In : British Journal of Cancer. 98, 10, p. 1653-1661 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Discovering early molecular determinants of leukemogenesis

Bagby, G. C., Mar 1 2008, In : Journal of Clinical Investigation. 118, 3, p. 847-850 4 p.

Research output: Contribution to journalComment/debate

10 Scopus citations
38 Scopus citations

TAT-mediated intracellular delivery of NPM-derived peptide induces apoptosis in leukemic cells and suppresses leukemogenesis in mice

Zhou, Y., Du, W., Koretsky, T., Bagby, G. C. & Pang, Q., Sep 15 2008, In : Blood. 112, 6, p. 2474-2483 10 p.

Research output: Contribution to journalArticle

25 Scopus citations
2007
Open Access
24 Scopus citations

In response [6]

Bagby, G. C. & Pejovic, T., Mar 15 2007, In : Cancer Research. 67, 6, p. 2902-2903 2 p.

Research output: Contribution to journalLetter

TNF-α induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells

Li, J., Sejas, D. P., Zhang, X., Qiu, Y., Nattamai, K. J., Rani, R., Rathbun, K. R., Geiger, H., Williams, D. A., Bagby, G. C. & Pang, Q., Nov 1 2007, In : Journal of Clinical Investigation. 117, 11, p. 3283-3295 13 p.

Research output: Contribution to journalArticle

96 Scopus citations
2006

Constitutional Marrow Failure: Introduction

Bagby, G. C., Jul 2006, In : Seminars in Hematology. 43, 3, p. 145-146 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Cytogenetic instability in ovarian epithelial cells from women at risk of ovarian cancer

Pejovic, T., Yates, J. E., Liu, H. Y., Hays, L. E., Akkari, Y., Torimaru, Y., Keeble, W., Rathbun, R. K., Rodgers, W. H., Bale, A. E., Ameziane, N., Zwaan, C. M., Errami, A., Thuillier, P., Cappuccini, F., Olson, S. B., Cain, J. M. & Bagby, G. C., Sep 15 2006, In : Cancer Research. 66, 18, p. 9017-9025 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Evaluation and lead optimization of anti-malarial acridones

Winter, R. W., Kelly, J. X., Smilkstein, M. J., Dodean, R., Bagby, G. C., Rathbun, R. K., Levin, J. I., Hinrichs, D. & Riscoe, M. K., Sep 1 2006, In : Experimental Parasitology. 114, 1, p. 47-56 10 p.

Research output: Contribution to journalArticle

70 Scopus citations

Fanconi Anemia

Bagby, G. C. & Alter, B. P., Jul 1 2006, In : Seminars in hematology. 43, 3, p. 147-156 10 p.

Research output: Contribution to journalArticle

119 Scopus citations

Immune defects in Fanconi anemia

Fagerlie, S. R. & Bagby, G. C., Jun 26 2006, In : Critical Reviews in Immunology. 26, 1, p. 81-96 16 p.

Research output: Contribution to journalReview article

26 Scopus citations

Novel inactivating mutations of FANCC in Brazilian patients with Fanconi anemia.

Yates, J., Keeble, W., Pals, G., Ameziane, N., van Spaendonk, R., Olson, S., Akkari, Y., Pasquini, R. & Bagby, G., Feb 2006, In : Human mutation. 27, 2, 1 p.

Research output: Contribution to journalArticle

2 Scopus citations

Nucleophosmin regulates cell cycle progression and stress response in hematopoietic stem/progenitor cells

Li, J., Sejas, D. P., Rani, R., Koretsky, T., Bagby, G. C. & Pang, Q., Jun 16 2006, In : Journal of Biological Chemistry. 281, 24, p. 16536-16545 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

The less-traveled Fanconi road

Bagby, G. C., Jun 1 2006, In : Blood. 107, 11, p. 4196-4197 2 p.

Research output: Contribution to journalReview article

1 Scopus citations
2005

Generation and molecular characterization of head and neck squamous cell lines of Fanconi anemia patients

Van Zeeburg, H. J. T., Snijders, P. J. F., Pals, G., Hermsen, M. A. J. A., Rooimans, M. A., Bagby, G., Soulier, J., Gluckman, E., Wennerberg, J., Leemans, C. R., Joenje, H. & Brakenhoff, R. H., Feb 15 2005, In : Cancer Research. 65, 4, p. 1271-1276 6 p.

Research output: Contribution to journalArticle

58 Scopus citations
2004

Hypoxia-induced nucleophosmin protects cell death through inhibition of p53

Li, J., Zhang, X., Sejas, D. P., Bagby, G. C. & Pang, Q., Oct 1 2004, In : Journal of Biological Chemistry. 279, 40, p. 41275-41279 5 p.

Research output: Contribution to journalArticle

116 Scopus citations

Impaired type I IFN-induced Jak/STAT signaling in FA-C cells and abnormal CD4+ Th cell subsets in Fancc-/- mice

Fagerlie, S. R., Koretsky, T., Torok-Storb, B. & Bagby, G. C., Sep 15 2004, In : Journal of Immunology. 173, 6, p. 3863-3870 8 p.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations

Marrow failure.

Bagby, G. C., Lipton, J. M., Sloand, E. M. & Schiffer, C. A., 2004, In : Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. p. 318-336 19 p.

Research output: Contribution to journalReview article

Open Access
41 Scopus citations

The Fanconi anemia proteins functionally interact with the protein kinase regulated by RNA (PKR)

Zhang, X., Li, J., Sejas, D. P., Rathbun, K. R., Bagby, G. C. & Pang, Q., Oct 15 2004, In : Journal of Biological Chemistry. 279, 42, p. 43910-43919 10 p.

Research output: Contribution to journalArticle

39 Scopus citations
2003

Acquired FANCA dysfunction and cytogenetic instability in adult acute myelogenous leukemia

Lensch, M. W., Tischkowitz, M., Christianson, T. A., Reifsteck, C. A., Speckhart, S. A., Jakobs, P. M., O'Dwyer, M. E., Olson, S. B., Le Beau, M. M., Hodgson, S. V., Mathew, C. G., Larson, R. A. & Bagby, G. C., Jul 1 2003, In : Blood. 102, 1, p. 7-16 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Cisplatin and the sensitive cell

Bagby, G. C. & Olson, S. B., May 1 2003, In : Nature medicine. 9, 5, p. 513-514 2 p.

Research output: Contribution to journalShort survey

8 Scopus citations

Genetic basis of Fanconi anemia

Bagby, G. C., Jan 1 2003, In : Current opinion in hematology. 10, 1, p. 68-76 9 p.

Research output: Contribution to journalReview article

129 Scopus citations

Nucleophosmin Interacts with and Inhibits the Catalytic Function of Eukaryotic Initiation Factor 2 Kinase PKR

Pang, Q., Christianson, T. A., Koretsky, T., Carlson, H., David, L., Keeble, W., Faulkner, G. R., Speckhart, A. & Bagby, G. C., Oct 24 2003, In : Journal of Biological Chemistry. 278, 43, p. 41709-41717 9 p.

Research output: Contribution to journalArticle

41 Scopus citations
2002

Expression of apoptosis-related genes in chronic cyclosporine nephrotoxicity in mice

Yang, C. W., Faulkner, G. R., Wahba, I. M., Christianson, T. A., Bagby, G. C., Jin, D. C., Abboud, H. E., Andoh, T. F. & Bennett, W. M., May 1 2002, In : American Journal of Transplantation. 2, 5, p. 391-399 9 p.

Research output: Contribution to journalArticle

75 Scopus citations

Fanconi anemia group A and C double-mutant mice: Functional evidence for a multi-protein Fanconi anemia complex

Noll, M., Battaile, K. P., Bateman, R., Lax, T. P., Rathbun, K., Reifsteck, C., Bagby, G., Finegold, M., Olson, S. & Grompe, M., Aug 12 2002, In : Experimental hematology. 30, 7, p. 679-688 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

The anti-apoptotic function of Hsp70 in the interferon-inducible double-stranded RNA-dependent protein kinase-mediated death signaling pathway requires the Fanconi anemia protein, FANCC

Pang, Q., Christianson, T. A., Keeble, W., Koretsky, T. & Bagby, G. C., Dec 20 2002, In : Journal of Biological Chemistry. 277, 51, p. 49638-49643 6 p.

Research output: Contribution to journalArticle

78 Scopus citations

The Fanconi anemia cell line HSC536N is not sensitive to interferon-γ and does not cleave PARP in response to Fas-mediated cell killing [5] (multiple letters)

Rutherford, T. R., Myatt, N. E., Gibson, F. M., Clarke, A. A. & Bagby, G. C., Apr 1 2002, In : Blood. 99, 7, p. 2627-2630 4 p.

Research output: Contribution to journalLetter

2001

FANCC interacts with Hsp70 to protect hematopoietic cells from IFN-γ/TNF-α-mediated cytotoxicity

Pang, Q., Keeble, W., Christianson, T. A., Faulkner, G. R. & Bagby, G. C., Aug 15 2001, In : EMBO Journal. 20, 16, p. 4478-4489 12 p.

Research output: Contribution to journalArticle

109 Scopus citations

Functional correction of FA-C cells with FANCC suppresses the expression of interferon γ-inducible genes

Fagerlie, S. R., Diaz, J., Christianson, T. A., McCartan, K., Keeble, W., Faulkner, G. R. & Bagby, G. C., May 15 2001, In : Blood. 97, 10, p. 3017-3024 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Hidradenitis suppurativa and Crohn's disease: Response to treatment with infliximab

Kempton, C. L., Bagby, G. & Collins, J. F., Nov 26 2001, In : Inflammatory Bowel Diseases. 7, 4, p. 323-326 4 p.

Research output: Contribution to journalArticle

141 Scopus citations