Gordon Mills

Professor

  • Source: Scopus
  • Calculated based on no. of publications stored in Pure and citations from Scopus
1976 …2021

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  • 2016

    Loss of ARID1A activates ANXA1, which serves as a predictive biomarker for trastuzumab resistance

    Berns, K., Sonnenblick, A., Gennissen, A., Brohée, S., Hijmans, E. M., Evers, B., Fumagalli, D., Desmedt, C., Loibl, S., Denkert, C., Neven, P., Guo, W., Zhang, F., Knijnenburg, T. A., Bosse, T., Van Der Heijden, M. S., Hindriksen, S., Nijkamp, W., Wessels, L. F. A., Joensuu, H. & 4 others, Mills, G. B., Beijersbergen, R. L., Sotiriou, C. & Bernards, R., Nov 1 2016, In: Clinical Cancer Research. 22, 21, p. 5238-5248 11 p.

    Research output: Contribution to journalArticlepeer-review

    23 Scopus citations
  • MAPK activation predicts poor outcome and the MEK inhibitor, selumetinib, reverses antiestrogen resistance in ER-positive high-grade serous ovarian cancer

    Hew, K. E., Miller, P. C., El-Ashry, D., Sun, J., Besser, A. H., Ince, T. A., Gu, M., Wei, Z., Zhang, G., Brafford, P., Gao, W., Lu, Y., Mills, G. B., Slingerland, J. M. & Simpkins, F., Feb 15 2016, In: Clinical Cancer Research. 22, 4, p. 935-947 13 p.

    Research output: Contribution to journalArticlepeer-review

    26 Scopus citations
  • Metabolic clusters of breast cancer in relation to gene- and protein expression subtypes

    Haukaas, T. H., Euceda, L. R., Giske�deg�rd, G. F., Lamichhane, S., Krohn, M., Jernstr�m, S., Aure, M. R., Lingj�rde, O. C., Schlichting, E., Garred, Ï., Due, E. U., Mills, G., Sahlberg, K. K., B�rresen-Dale, A. L. & Bathen, T. F., Jan 1 2016, In: Cancer and Metabolism. 4, 1, 12.

    Research output: Contribution to journalArticlepeer-review

  • Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

    Ceccarelli, M., Barthel, F. P., Malta, T. M., Sabedot, T. S., Salama, S. R., Murray, B. A., Morozova, O., Newton, Y., Radenbaugh, A., Pagnotta, S. M., Anjum, S., Wang, J., Manyam, G., Zoppoli, P., Ling, S., Rao, A. A., Grifford, M., Cherniack, A. D., Zhang, H., Poisson, L. & 188 others, Carlotti, C. G., Tirapelli, D. P. D. C., Rao, A., Mikkelsen, T., Lau, C. C., Yung, W. K. A., Rabadan, R., Huse, J., Brat, D. J., Lehman, N. L., Barnholtz-Sloan, J. S., Zheng, S., Hess, K., Rao, G., Meyerson, M., Beroukhim, R., Cooper, L., Akbani, R., Wrensch, M., Haussler, D., Aldape, K. D., Laird, P. W., Gutmann, D. H., Noushmehr, H., Arachchi, H., Auman, J. T., Balasundaram, M., Balu, S., Barnett, G., Baylin, S., Bell, S., Benz, C., Bir, N., Black, K. L., Bodenheimer, T., Boice, L., Bootwalla, M. S., Bowen, J., Bristow, C. A., Butterfield, Y. S. N., Chen, Q. R., Chin, L., Cho, J., Chuah, E., Chudamani, S., Coetzee, S. G., Cohen, M. L., Colman, H., Couce, M., D'Angelo, F., Davidsen, T., Davis, A., Demchok, J. A., Devine, K., Ding, L., Duell, R., Elder, J. B., Eschbacher, J. M., Fehrenbach, A., Ferguson, M., Frazer, S., Fuller, G., Fulop, J., Gabriel, S. B., Garofano, L., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Giannini, C., Gibson, W. J., Hadjipanayis, A., Hayes, D. N., Heiman, D. I., Hermes, B., Hilty, J., Hoadley, K. A., Hoyle, A. P., Huang, M., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Ju, Z., Kastl, A., Kendler, A., Kim, J., Kucherlapati, R., Lai, P. H., Lawrence, M. S., Lee, S., Leraas, K. M., Lichtenberg, T. M., Lin, P., Liu, Y., Liu, J., Ljubimova, J. Y., Lu, Y., Ma, Y., Maglinte, D. T., Mahadeshwar, H. S., Marra, M. A., McGraw, M., McPherson, C., Meng, S., Mieczkowski, P. A., Miller, C. R., Mills, G. B., Moore, R. A., Mose, L. E., Mungall, A. J., Naresh, R., Naska, T., Neder, L., Noble, M. S., Noss, A., O'Neill, B. P., Ostrom, Q. T., Palmer, C., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Pierson, C. R., Pihl, T., Protopopov, A., Radenbaugh, A., Ramirez, N. C., Rathmell, W. K., Ren, X., Roach, J., Robertson, A. G., Saksena, G., Schein, J. E., Schumacher, S. E., Seidman, J., Senecal, K., Seth, S., Shen, H., Shi, Y., Shih, J., Shimmel, K., Sicotte, H., Sifri, S., Silva, T., Simons, J. V., Singh, R., Skelly, T., Sloan, A. E., Sofia, H. J., Soloway, M. G., Song, X., Sougnez, C., Souza, C., Staugaitis, S. M., Sun, H., Sun, C., Tan, D., Tang, J., Tang, Y., Thorne, L., Trevisan, F. A., Triche, T., Van Den Berg, D. J., Veluvolu, U., Voet, D., Wan, Y., Wang, Z., Warnick, R., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Williams, F., Wise, L., Wolinsky, Y., Wu, J., Xu, A. W., Yang, L., Yang, L., Zack, T. I., Zenklusen, J. C., Zhang, J., Zhang, W., Zhang, J., Zmuda, E., Noushmehr, H., Iavarone, A. & Verhaak, R. G. W., Jan 28 2016, In: Cell. 164, 3, p. 550-563 14 p.

    Research output: Contribution to journalArticlepeer-review

    849 Scopus citations
  • mTOR inhibitors suppress homologous recombination repair and synergize with PARP inhibitors via regulating SUV39H1 in BRCA-proficient triple-negative breast cancer

    Mo, W., Liu, Q., Lin, C. C. J., Dai, H., Peng, Y., Liang, Y., Peng, G., Meric-Bernstam, F., Mills, G. B., Li, K. & Lin, S. Y., Apr 1 2016, In: Clinical Cancer Research. 22, 7, p. 1699-1712 14 p.

    Research output: Contribution to journalArticlepeer-review

    52 Scopus citations
  • Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma

    Chen, F., Zhang, Y., Şenbabaoğlu, Y., Ciriello, G., Yang, L., Reznik, E., Shuch, B., Micevic, G., De Velasco, G., Shinbrot, E., Noble, M. S., Lu, Y., Covington, K. R., Xi, L., Drummond, J. A., Muzny, D., Kang, H., Lee, J., Tamboli, P., Reuter, V. & 20 others, Shelley, C. S., Kaipparettu, B. A., Bottaro, D. P., Godwin, A. K., Gibbs, R. A., Getz, G., Kucherlapati, R., Park, P. J., Sander, C., Henske, E. P., Zhou, J. H., Kwiatkowski, D. J., Ho, T. H., Choueiri, T. K., Hsieh, J. J., Akbani, R., Mills, G. B., Hakimi, A. A., Wheeler, D. A. & Creighton, C. J., Mar 15 2016, In: Cell Reports. 14, 10, p. 2476-2489 14 p.

    Research output: Contribution to journalArticlepeer-review

    184 Scopus citations
  • Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set

    Roszik, J., Haydu, L. E., Hess, K. R., Oba, J., Joon, A. Y., Siroy, A. E., Karpinets, T. V., Stingo, F. C., Baladandayuthapani, V., Tetzlaff, M. T., Wargo, J. A., Chen, K., Forget, M. A., Haymaker, C. L., Chen, J. Q., Meric-Bernstam, F., Eterovic, A. K., Shaw, K. R., Mills, G. B., Gershenwald, J. E. & 8 others, Radvanyi, L. G., Hwu, P., Futreal, P. A., Gibbons, D. L., Lazar, A. J., Bernatchez, C., Davies, M. A. & Woodman, S. E., Oct 25 2016, In: BMC Medicine. 14, 1, 168.

    Research output: Contribution to journalArticlepeer-review

    71 Scopus citations
  • Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer

    Bissig-Choisat, B., Kettlun-Leyton, C., Legras, X. D., Zorman, B., Barzi, M., Chen, L. L., Amin, M. D., Huang, Y. H., Pautler, R. G., Hampton, O. A., Prakash, M. M., Yang, D., Borowiak, M., Muzny, D., Doddapaneni, H. V., Hu, J., Shi, Y., Gaber, M. W., Hicks, M. J., Thompson, P. A. & 9 others, Lu, Y., Mills, G. B., Finegold, M., Goss, J. A., Parsons, D. W., Vasudevan, S. A., Sumazin, P., López-Terrada, D. & Bissig, K. D., Aug 1 2016, In: Journal of Hepatology. 65, 2, p. 325-333 9 p.

    Research output: Contribution to journalArticlepeer-review

    25 Scopus citations
  • Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway

    Jeong, A. L., Han, S., Lee, S., Su Park, J., Lu, Y., Yu, S., Li, J., Chun, K. H., Mills, G. B. & Yang, Y., Jun 7 2016, In: Scientific Reports. 6, 27391.

    Research output: Contribution to journalArticlepeer-review

    14 Scopus citations
  • Personalized preclinical trials in BRAF Inhibitor-resistant patient-derived xenograft models identify second-line combination therapies

    Krepler, C., Xiao, M., Sproesser, K., Brafford, P. A., Shannan, B., Beqiri, M., Liu, Q., Xu, W., Garman, B., Nathanson, K. L., Xu, X., Karakousis, G. C., Mills, G. B., Lu, Y., Ahmed, T. A., Poulikakos, P. I., Caponigro, G., Boehm, M., Peters, M., Schuchter, L. M. & 2 others, Tweeraratna, A. & Herlyn, M., Apr 1 2016, In: Clinical Cancer Research. 22, 7, p. 1592-1602 11 p.

    Research output: Contribution to journalArticlepeer-review

    77 Scopus citations
  • Phosphatase PTP4A3 promotes triple-negative breast cancer growth and predicts poor patient survival

    Hollander, P. D., Rawls, K., Tsimelzon, A., Shepherd, J., Mazumdar, A., Hill, J., Fuqua, S. A. W., Chang, J. C., Osborne, C. K., Hilsenbeck, S. G., Mills, G. B. & Brown, P. H., Apr 1 2016, In: Cancer Research. 76, 7, p. 1942-1953 12 p.

    Research output: Contribution to journalArticlepeer-review

    42 Scopus citations
  • Phosphorylation-dependent cleavage regulates von Hippel Lindau proteostasis and function

    German, P., Bai, S., Liu, X. D., Sun, M., Zhou, L., Kalra, S., Zhang, X., Minelli, R., Scott, K. L., Mills, G. B., Jonasch, E. & Ding, Z., Sep 22 2016, In: Oncogene. 35, 38, p. 4973-4980 8 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • PKCiota promotes ovarian tumor progression through deregulation of cyclin e

    Nanos-Webb, A., Bui, T., Karakas, C., Zhang, D., Carey, J. P. W., Mills, G. B., Hunt, K. K. & Keyomarsi, K., May 12 2016, In: Oncogene. 35, 19, p. 2428-2440 13 p.

    Research output: Contribution to journalArticlepeer-review

    14 Scopus citations
  • Proteomic characterization of head and neck cancer patient-derived xenografts

    Li, H., Wheeler, S., Park, Y., Ju, Z., Thomas, S. M., Fichera, M., Egloff, A. M., Lui, V. W., Duvvuri, U., Bauman, J. E., Mills, G. B. & Grandis, J. R., Mar 2016, In: Molecular Cancer Research. 14, 3, p. 278-286 9 p.

    Research output: Contribution to journalArticlepeer-review

    31 Scopus citations
  • Rab11-FIP1C is a critical negative regulator in ErbB2-mediated mammary tumor progression

    Boulay, P. L., Mitchell, L., Turpin, J., Huot-Marchand, J. É., Lavoie, C., Sanguin-Gendreau, V., Jones, L., Mitra, S., Livingstone, J. M., Campbell, S., Hallett, M., Mills, G. B., Park, M., Chodosh, L., Strathdee, D., Norman, J. C. & Muller, W. J., May 1 2016, In: Cancer Research. 76, 9, p. 2662-2674 13 p.

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations
  • Rab25 acts as an oncogene in luminal B breast cancer and is causally associated with Snail driven EMT

    Mitra, S., Federico, L., Zhao, W., Dennison, J., Sarkar, T. R., Zhang, F., Takiar, V., Cheng, K. W., Mani, S., Lee, J. S. & Mills, G. B., 2016, In: Oncotarget. 7, 26, p. 40252-40265 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    22 Scopus citations
  • Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors

    Zhang, G., Frederick, D. T., Wu, L., Wei, Z., Krepler, C., Srinivasan, S., Chae, Y. C., Xu, X., Choi, H., Dimwamwa, E., Ope, O., Shannan, B., Basu, D., Zhang, D., Guha, M., Xiao, M., Randell, S., Sproesser, K., Xu, W., Liu, J. & 22 others, Karakousis, G. C., Schuchter, L. M., Gangadhar, T. C., Amaravadi, R. K., Gu, M., Xu, C., Ghosh, A., Xu, W., Tian, T., Zhang, J., Zha, S., Liu, Q., Brafford, P., Weeraratna, A., Davies, M. A., Wargo, J. A., Avadhani, N. G., Lu, Y., Mills, G. B., Altieri, D. C., Flaherty, K. T. & Herlyn, M., May 2 2016, In: Journal of Clinical Investigation. 126, 5, p. 1834-1856 23 p.

    Research output: Contribution to journalArticlepeer-review

    124 Scopus citations
  • The degree of intratumor mutational heterogeneity varies by primary tumor sub-site

    Ledgerwood, L. G., Kumar, D., Eterovic, A. K., Wick, J., Chen, K., Zhao, H., Tazi, L., Manna, P., Kerley, S., Joshi, R., Wang, L., Chiosea, S. I., Garnett, J. D., Tsue, T. T., Chien, J., Mills, G. B., Grandis, J. R. & Thomas, S. M., May 10 2016, In: Oncotarget. 7, 19, p. 27185-27198 14 p.

    Research output: Contribution to journalArticlepeer-review

    27 Scopus citations
  • The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment

    Turpin, J., Ling, C., Crosby, E. J., Hartman, Z. C., Simond, A. M., Chodosh, L. A., Rennhack, J. P., Andrechek, E. R., Ozcelik, J., Hallett, M., Mills, G. B., Cardiff, R. D., Gray, J. W., Griffith, O. L. & Muller, W. J., Nov 24 2016, In: Oncogene. 35, 47, p. 6053-6064 12 p.

    Research output: Contribution to journalArticlepeer-review

    31 Scopus citations
  • Transgenic expression of the mitochondrial chaperone TNFR-associated protein 1 (TRAP1) accelerates prostate cancer development

    Lisanti, S., Garlick, D. S., Bryant, K. G., Tavecchio, M., Mills, G. B., Lu, Y., Kossenkov, A. V., Showe, L. C., Languino, L. R. & Altieri, D. C., Nov 25 2016, In: Journal of Biological Chemistry. 291, 48, p. 25247-25254 8 p.

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations
  • Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials

    Overman, M. J., Morris, V., Kee, B., Fogelman, D., Xiao, L., Eng, C., Dasari, A., Shroff, R., Mazard, T., Shaw, K., Vilar, E., Raghav, K., Shureiqi, I., Liang, L., Mills, G. B., Wolff, R. A., Hamilton, S., Meric-Bernstam, F., Abbruzzese, J., Morris, J. & 2 others, Maru, D. & Kopetz, S., Jun 18 2016, In: Annals of Oncology. 27, 6, p. 1068-1074 7 p.

    Research output: Contribution to journalArticlepeer-review

    22 Scopus citations
  • Verteporfin inhibits YAP function through up-regulating 14-3-3σ sequestering YAP in the cytoplasm

    Wang, C., Zhu, X., Feng, W., Yu, Y., Jeong, K., Guo, W., Lu, Y. & Mills, G. B., 2016, In: American Journal of Cancer Research. 6, 1, p. 27-37 11 p.

    Research output: Contribution to journalArticlepeer-review

    94 Scopus citations
  • Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma

    Park, Y. Y., Sohn, B. H., Johnson, R. L., Kang, M. H., Kim, S. B., Shim, J. J., Mangala, L. S., Kim, J. H., Yoo, J. E., Rodriguez-Aguayo, C., Pradeep, S., Hwang, J. E., Jang, H. J., Lee, H. S., Rupaimoole, R., Lopez-Berestein, G., Jeong, W., Park, I. S., Park, Y. N., Sood, A. K. & 2 others, Mills, G. B. & Lee, J. S., Jan 1 2016, In: Hepatology. 63, 1, p. 159-172 14 p.

    Research output: Contribution to journalArticlepeer-review

    56 Scopus citations
  • 2015

    Ability to generate patient-derived Breast cancer xenografts is enhanced in chemoresistant disease and predicts poor patient outcomes

    McAuliffe, P. F., Evans, K. W., Akcakanat, A., Chen, K., Zheng, X., Zhao, H., Eterovic, A. K., Sangai, T., Holder, A. M., Sharma, C., Chen, H., Do, K. A., Tarco, E., Gagea, M., Naff, K. A., Sahin, A., Multani, A. S., Black, D. M., Mittendorf, E. A., Bedrosian, I. & 3 others, Mills, G. B., Gonzalez-Angulo, A. M. & Meric-Bernstam, F., Sep 1 2015, In: PloS one. 10, 9, e0136851.

    Research output: Contribution to journalArticlepeer-review

    28 Scopus citations
  • An integrated molecular analysis of lung adenocarcinomas identifies potential therapeutic targets among TTF1-negative tumors, including DNA Repair Proteins and Nrf2

    Cardnell, R. J. G., Behrens, C., Diao, L., Fan, Y. H., Tang, X., Tong, P., Minna, J. D., Mills, G. B., Heymach, J. V., Wistuba, I. I., Wang, J. & Byers, L. A., Aug 1 2015, In: Clinical Cancer Research. 21, 15, p. 3480-3491 12 p.

    Research output: Contribution to journalArticlepeer-review

    30 Scopus citations
  • A putative biomarker signature for clinically effective AKT inhibition: Correlation of in vitro, in vivo and clinical data identifies the importance of modulation of the mTORC1 pathway

    Cheraghchi-Bashi, A., Parker, C. A., Curry, E., Salazar, J. F., Gungor, H., Saleem, A., Cunnea, P., Rama, N., Salinas, C., Mills, G. B., Morris, S. R., Kumar, R., Gabra, H. & Stronach, E. A., 2015, In: Oncotarget. 6, 39, p. 41736-41749 14 p.

    Research output: Contribution to journalArticlepeer-review

    16 Scopus citations
  • ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP Inhibitors

    Shen, J., Peng, Y., Wei, L., Zhang, W., Yang, L., Lan, L., Kapoor, P., Ju, Z., Mo, Q., Shih, I. M., Uray, I. P., Wu, X., Brown, P. H., Shen, X., Mills, G. B. & Peng, G., Jul 1 2015, In: Cancer discovery. 5, 7, p. 752-767 16 p.

    Research output: Contribution to journalArticlepeer-review

    197 Scopus citations
  • Association of somatic mutations of ADAMTS genes with chemotherapy sensitivity and survival in high-grade serous ovarian carcinoma

    Liu, Y., Yasukawa, M., Chen, K., Hu, L., Broaddus, R. R., Ding, L., Mardis, E. R., Spellman, P., Levine, D. A., Mills, G. B., Shmulevich, I., Sood, A. K. & Zhang, W., Jul 1 2015, In: JAMA Oncology. 1, 4, p. 486-494 9 p.

    Research output: Contribution to journalArticlepeer-review

    24 Scopus citations
  • Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis

    Liu, X. D., Yao, J., Tripathi, D. N., Ding, Z., Xu, Y., Sun, M., Zhang, J., Bai, S., German, P., Hoang, A., Zhou, L., Jonasch, D., Zhang, X., Conti, C. J., Efstathiou, E., Tannir, N. M., Eissa, N. T., Mills, G. B., Walker, C. L. & Jonasch, E., May 7 2015, In: Oncogene. 34, 19, p. 2450-2460 11 p.

    Research output: Contribution to journalArticlepeer-review

    49 Scopus citations
  • Beyond BRAFV600: Clinical mutation panel testing by next-generation sequencing in advanced melanoma

    Siroy, A. E., Boland, G. M., Milton, D. R., Roszik, J., Frankian, S., Malke, J., Haydu, L., Prieto, V. G., Tetzlaff, M., Ivan, D., Wang, W. L., Torres-Cabala, C., Curry, J., Roy-Chowdhuri, S., Broaddus, R., Rashid, A., Stewart, J., Gershenwald, J. E., Amaria, R. N., Patel, S. P. & 17 others, Papadopoulos, N. E., Bedikian, A., Hwu, W. J., Hwu, P., Diab, A., Woodman, S. E., Aldape, K. D., Luthra, R., Patel, K. P., Shaw, K. R., Mills, G. B., Mendelsohn, J., Meric-Bernstam, F., Kim, K. B., Routbort, M. J., Lazar, A. J. & Davies, M. A., Feb 13 2015, In: Journal of Investigative Dermatology. 135, 2, p. 508-515 8 p.

    Research output: Contribution to journalArticlepeer-review

    90 Scopus citations
  • Characterization of the role rab25 in energy metabolism and cancer using extracellular flux analysis and material balance

    Mitra, S., Molina, J., Mills, G. B. & Ennison, J. B. D., 2015, In: Methods in Molecular Biology. 1298, p. 195-205 11 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours

    Ince, T. A., Sousa, A. D., Jones, M. A., Harrell, J. C., Agoston, E. S., Krohn, M., Selfors, L. M., Liu, W., Chen, K., Yong, M., Buchwald, P., Wang, B., Hale, K. S., Cohick, E., Sergent, P., Witt, A., Kozhekbaeva, Z., Gao, S., Agoston, A. T., Merritt, M. A. & 5 others, Foster, R., Rueda, B. R., Crum, C. P., Brugge, J. S. & Mills, G. B., Jun 17 2015, In: Nature communications. 6, 7419.

    Research output: Contribution to journalArticlepeer-review

    100 Scopus citations
  • Clinical actionability enhanced through deep targeted sequencing of solid tumors

    Chen, K., Meric-Bernstam, F., Zhao, H., Zhang, Q., Ezzeddine, N., Tang, L. Y., Qi, Y., Mao, Y., Chen, T., Chong, Z., Zhou, W., Zheng, X., Johnson, A., Aldape, K. D., Routbort, M. J., Luthra, R., Kopetz, S., Davies, M. A., De Groot, J., Moulder, S. & 6 others, Vinod, R., Farhangfar, C. J., Shaw, K. M., Mendelsohn, J., Mills, G. B. & Eterovic, A. K., Mar 1 2015, In: Clinical chemistry. 61, 3, p. 544-553 10 p.

    Research output: Contribution to journalArticlepeer-review

    71 Scopus citations
  • Clinical next generation sequencing to identify actionable aberrations in a phase I program

    Boland, G. M., Piha-Paul, S. A., Subbiah, V., Routbort, M., Herbrich, S. M., Baggerly, K., Patel, K. P., Brusco, L., Horombe, C., Naing, A., Fu, S., Hong, D. S., Janku, F., Johnson, A., Broaddus, R., Luthra, R., Shaw, K., Mendelsohn, J., Mills, G. B. & Meric-Bernstam, F., 2015, In: Oncotarget. 6, 24, p. 20099-20110 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    33 Scopus citations
  • Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma

    Kwong, L. N., Boland, G. M., Frederick, D. T., Helms, T. L., Akid, A. T., Miller, J. P., Jiang, S., Cooper, Z. A., Song, X., Seth, S., Kamara, J., Protopopov, A., Mills, G. B., Flaherty, K. T., Wargo, J. A. & Chin, L., Apr 1 2015, In: Journal of Clinical Investigation. 125, 4, p. 1459-1470 12 p.

    Research output: Contribution to journalArticlepeer-review

    69 Scopus citations
  • Comparison of gene expression patterns across 12 tumor types identifies a cancer supercluster characterized by TP53 mutations and cell cycle defects

    Martínez, E., Yoshihara, K., Kim, H., Mills, G. M., Treviño, V. & Verhaak, R. G. W., May 21 2015, In: Oncogene. 34, 21, p. 2732-2740 9 p.

    Research output: Contribution to journalArticlepeer-review

    32 Scopus citations
  • Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas

    Brat, D. J., Verhaak, R. G. W., Aldape, K. D., Yung, W. K. A., Salama, S. R., Cooper, L. A. D., Rheinbay, E., Miller, C. R., Vitucci, M., Morozova, O., Robertson, A. G., Noushmehr, H., Laird, P. W., Cherniack, A. D., Akbani, R., Huse, J. T., Ciriello, G., Poisson, L. M., Barnholtz-Sloan, J. S., Berger, M. S. & 287 others, Brennan, C., Colen, R. R., Colman, H., Flanders, A. E., Giannini, C., Grifford, M., Iavarone, A., Jain, R., Joseph, I., Kim, J., Kasaian, K., Mikkelsen, T., Murray, B. A., O'Neill, B. P., Pachter, L., Parsons, D. W., Sougnez, C., Sulman, E. P., Vandenberg, S. R., Van Meir, E. G., Von Deimling, A., Zhang, H., Crain, D., Lau, K., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, T., Sherman, M., Yena, P., Black, A., Bowen, J., Dicostanzo, K., Gastier-Foster, J., Leraas, K. M., Lichtenberg, T. M., Pierson, C. R., Ramirez, N. C., Taylor, C., Weaver, S., Wise, L., Zmuda, E., Davidsen, T., Demchok, J. A., Eley, G., Ferguson, M. L., Hutter, C. M., Shaw, K. R. M., Ozenberger, B. A., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zenklusen, J. C., Ayala, B., Baboud, J., Chudamani, S., Jensen, M. A., Liu, J., Pihl, T., Raman, R., Wan, Y., Wu, Y., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., Baylin, S. B., Beroukhim, R., Bootwalla, M. S., Bowlby, R., Bristow, C. A., Brooks, D., Butterfield, Y., Carlsen, R., Carter, S., Chin, L., Chu, A., Chuah, E., Cibulskis, K., Clarke, A., Coetzee, S. G., Dhalla, N., Fennell, T., Fisher, S., Gabriel, S., Getz, G., Gibbs, R., Guin, R., Hadjipanayis, A., Hayes, D. N., Hinoue, T., Hoadley, K., Holt, R. A., Hoyle, A. P., Jefferys, S. R., Jones, S., Jones, C. D., Kucherlapati, R., Lai, P. H., Lander, E., Lee, S., Lichtenstein, L., Ma, Y., Maglinte, D. T., Mahadeshwar, H. S., Marra, M. A., Mayo, M., Meng, S., Meyerson, M. L., Mieczkowski, P. A., Moore, R. A., Mose, L. E., Mungall, A. J., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Protopopov, A., Ren, X., Roach, J., Sabedot, T. S., Schein, J., Schumacher, S. E., Seidman, J. G., Seth, S., Shen, H., Simons, J. V., Sipahimalani, P., Soloway, M. G., Song, X., Sun, H., Tabak, B., Tam, A., Tan, D., Tang, J., Thiessen, N., Triche, T., Van Den Berg, D. J., Veluvolu, U., Waring, S., Weisenberger, D. J., Wilkerson, M. D., Wong, T., Wu, J., Xi, L., Xu, A. W., Yang, L., Zack, T. I., Zhang, J., Aksoy, B. A., Arachchi, H., Benz, C., Bernard, B., Carlin, D., Cho, J., DiCara, D., Frazer, S., Fuller, G. N., Gao, J. J., Gehlenborg, N., Haussler, D., Heiman, D. I., Iype, L., Jacobsen, A., Ju, Z., Katzman, S., Kim, H., Knijnenburg, T., Kreisberg, R. B., Lawrence, M. S., Lee, W., Leinonen, K., Lin, P., Ling, S., Liu, W., Liu, Y., Liu, Y., Lu, Y., Mills, G., Ng, S., Noble, M. S., Paull, E., Rao, A., Reynolds, S., Saksena, G., Sanborn, Z., Sander, C., Schultz, N., Senbabaoglu, Y., Shen, R., Shmulevich, I., Sinha, R., Stuart, J., Sumer, S. O., Sun, Y., Tasman, N., Taylor, B. S., Voet, D., Weinhold, N., Weinstein, J. N., Yang, D., Yoshihara, K., Zheng, S., Zhang, W., Zou, L., Abel, T., Sadeghi, S., Cohen, M. L., Eschbacher, J., Hattab, E. M., Raghunathan, A., Schniederjan, M. J., Aziz, D., Barnett, G., Barrett, W., Bigner, D. D., Boice, L., Brewer, C., Calatozzolo, C., Campos, B., Carlotti, C. G., Chan, T. A., Cuppini, L., Curley, E., Cuzzubbo, S., Devine, K., DiMeco, F., Duell, R., Elder, J. B., Fehrenbach, A., Finocchiaro, G., Friedman, W., Fulop, J., Gardner, J., Hermes, B., Herold-Mende, C., Jungk, C., Kendler, A., Lehman, N. L., Lipp, E., Liu, O., Mandt, R., McGraw, M., Mclendon, R., McPherson, C., Neder, L., Nguyen, P., Noss, A., Nunziata, R., Ostrom, Q. T., Palmer, C., Perin, A., Pollo, B., Potapov, A., Potapova, O., Rathmell, W. K., Rotin, D., Scarpace, L., Schilero, C., Senecal, K., Shimmel, K., Shurkhay, V., Sifri, S., Singh, R., Sloan, A. E., Smolenski, K., Staugaitis, S. M., Steele, R., Thorne, L., Tirapelli, D. P. C., Unterberg, A., Vallurupalli, M., Wang, Y., Warnick, R., Williams, F., Wolinsky, Y., Bell, S., Rosenberg, M., Stewart, C., Huang, F., Grimsby, J. L., Radenbaugh, A. J. & Zhang, J., Jun 25 2015, In: New England Journal of Medicine. 372, 26, p. 2481-2498 18 p.

    Research output: Contribution to journalArticlepeer-review

    1404 Scopus citations
  • Comprehensive genomic analysis identifies novel subtypes and targets of triple-negative breast cancer

    Burstein, M. D., Tsimelzon, A., Poage, G. M., Covington, K. R., Contreras, A., Fuqua, S. A. W., Savage, M. I., Osborne, C. K., Hilsenbeck, S. G., Chang, J. C., Mills, G. B., Lau, C. C. & Brown, P. H., Apr 1 2015, In: Clinical Cancer Research. 21, 7, p. 1688-1698 11 p.

    Research output: Contribution to journalArticlepeer-review

    487 Scopus citations
  • Comprehensive genomic characterization of head and neck squamous cell carcinomas

    The Cancer Genome Atlas Network, Jan 29 2015, In: Nature. 517, 7536, p. 576-582 7 p.

    Research output: Contribution to journalArticlepeer-review

    1792 Scopus citations
  • Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers

    Yan, X., Hu, Z., Feng, Y., Hu, X., Yuan, J., Zhao, S. D., Zhang, Y., Yang, L., Shan, W., He, Q., Fan, L., Kandalaft, L. E., Tanyi, J. L., Li, C., Yuan, C. X., Zhang, D., Yuan, H., Hua, K., Lu, Y., Katsaros, D. & 10 others, Huang, Q., Montone, K., Fan, Y., Coukos, G., Boyd, J., Sood, A. K., Rebbeck, T., Mills, G. B., Dang, C. V. & Zhang, L., Oct 12 2015, In: Cancer Cell. 28, 4, p. 529-540 12 p., 2143.

    Research output: Contribution to journalArticlepeer-review

    379 Scopus citations
  • Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

    Ciriello, G., Gatza, M. L., Beck, A. H., Wilkerson, M. D., Rhie, S. K., Pastore, A., Zhang, H., McLellan, M., Yau, C., Kandoth, C., Bowlby, R., Shen, H., Hayat, S., Fieldhouse, R., Lester, S. C., Tse, G. M. K., Factor, R. E., Collins, L. C., Allison, K. H., Chen, Y. Y. & 119 others, Jensen, K., Johnson, N. B., Oesterreich, S., Mills, G. B., Cherniack, A. D., Robertson, G., Benz, C., Sander, C., Laird, P. W., Hoadley, K. A., King, T. A., Akbani, R., Auman, J. T., Balasundaram, M., Balu, S., Barr, T., Benz, S., Berrios, M., Beroukhim, R., Bodenheimer, T., Boice, L., Bootwalla, M. S., Bowen, J., Brooks, D., Chin, L., Cho, J., Chudamani, S., Davidsen, T., Demchok, J. A., Dennison, J. B., Ding, L., Felau, I., Ferguson, M. L., Frazer, S., Gabriel, S. B., Gao, J. J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Gibson, W. J., Hayes, D. N., Heiman, D. I., Holbrook, A., Holt, R. A., Hoyle, A. P., Hu, H., Huang, M., Hutter, C. M., Hwang, E. S., Jefferys, S. R., Jones, S. J. M., Ju, Z., Kim, J., Lai, P. H., Lawrence, M. S., Leraas, K. M., Lichtenberg, T. M., Lin, P., Ling, S., Liu, J., Liu, W., Lolla, L., Lu, Y., Ma, Y., Maglinte, D. T., Mardis, E., Marks, J., Marra, M. A., McAllister, C., Meng, S., Meyerson, M., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Naresh, R., Noble, M. S., Olopade, O., Parker, J. S., Pihl, T., Saksena, G., Schumacher, S. E., Shaw, K. R. M., Ramirez, N. C., Rathmell, W. K., Roach, J., Robertson, A. G., Schein, J. E., Schultz, N., Sheth, M., Shi, Y., Shih, J., Shelley, C. S., Shriver, C., Simons, J. V., Sofia, H. J., Soloway, M. G., Sougnez, C., Sun, C., Tarnuzzer, R., Tiezzi, D. G., Van Den Berg, D. J., Voet, D., Wan, Y., Wang, Z., Weinstein, J. N., Weisenberger, D. J., Wilson, R., Wise, L., Wiznerowicz, M., Wu, J., Wu, Y., Yang, L., Zack, T. I., Zenklusen, J. C., Zhang, J., Zmuda, E. & Perou, C. M., Oct 8 2015, In: Cell. 163, 2, p. 506-519 14 p.

    Research output: Contribution to journalArticlepeer-review

    850 Scopus citations
  • Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities

    Skoulidis, F., Byers, L. A., Diao, L., Papadimitrakopoulou, V. A., Tong, P., Izzo, J., Behrens, C., Kadara, H., Parra, E. R., Canales, J. R., Zhang, J., Giri, U., Gudikote, J., Cortez, M. A., Yang, C., Fan, Y., Peyton, M., Girard, L., Coombes, K. R., Toniatti, C. & 17 others, Heffernan, T. P., Choi, M., Frampton, G. M., Miller, V., Weinstein, J. N., Herbst, R. S., Wong, K. K., Zhang, J., Sharma, P., Mills, G. B., Hong, W. K., Minna, J. D., Allison, J. P., Futrea, A., Wang, J., Wistuba, I. I. & Heymach, J. V., Aug 1 2015, In: Cancer discovery. 5, 8, p. 861-878 18 p.

    Research output: Contribution to journalArticlepeer-review

    361 Scopus citations
  • Cupid: Simultaneous reconstruction of micrornatarget and cerna networks

    Chiu, H. S., Llobet-Navas, D., Yang, X., Chung, W. J., Ambesi-Impiombato, A., Iyer, A., Kim, H. R., Seviour, E. G., Luo, Z., Sehgal, V., Moss, T., Lu, Y., Ram, P., Silva, J., Mills, G. B., Califano, A. & Sumazin, P., Feb 1 2015, In: Genome Research. 25, 2, p. 257-267 11 p.

    Research output: Contribution to journalArticlepeer-review

    52 Scopus citations
  • Cytoplasmic p27 promotes epithelial-mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation

    Zhao, D., Besser, A. H., Wander, S. A., Sun, J., Zhou, W., Wang, B., Ince, T., Durante, M. A., Guo, W., Mills, G., Theodorescu, D. & Slingerland, J., Oct 1 2015, In: Oncogene. 34, 43, p. 5447-5459 13 p.

    Research output: Contribution to journalArticlepeer-review

    76 Scopus citations
  • Death-associated protein kinase 1 promotes growth of p53-mutant cancers

    Zhao, J., Zhao, D., Poage, G. M., Mazumdar, A., Zhang, Y., Hill, J. L., Hartman, Z. C., Savage, M. I., Mills, G. B. & Brown, P. H., Jul 1 2015, In: Journal of Clinical Investigation. 125, 7, p. 2707-2720 14 p.

    Research output: Contribution to journalArticlepeer-review

    36 Scopus citations
  • Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer

    Korkola, J. E., Collisson, E. A., Heiser, L., Oates, C., Bayani, N., Itani, S., Esch, A., Thompson, W., Griffith, O. L., Wang, N. J., Kuo, W. L., Cooper, B., Billig, J., Ziyad, S., Hung, J. L., Feiler, H., Lu, Y., Mills, G. B., Spellman, P. T., Tomlin, C. & 3 others, Mukherjee, S., Gray, J. W. & Jakkula, L., Jul 16 2015, In: PloS one. 10, 7, e0133219.

    Research output: Contribution to journalArticlepeer-review

    13 Scopus citations
  • Development of a robust classifier for quality control of reverse-phase protein arrays

    Ju, Z., Liu, W., Roebuck, P. L., Siwak, D. R., Zhang, N., Lu, Y., Davies, M. A., Akbani, R., Weinstein, J. N., Mills, G. B. & Coombes, K. R., Mar 15 2015, In: Bioinformatics. 31, 6, p. 912-918 7 p.

    Research output: Contribution to journalArticlepeer-review

    23 Scopus citations
  • Elafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors

    Labidi-Galy, S. I., Clauss, A., Ng, V., Duraisamy, S., Elias, K. M., Piao, H. Y., Bilal, E., Davidowitz, R. A., Lu, Y., Badalian-Very, G., Györffy, B., Kang, U. B., Ficarro, S., Ganesan, S., Mills, G. B., Marto, J. A. & Drapkin, R., Jan 15 2015, In: Oncogene. 34, 3, p. 299-309 11 p.

    Research output: Contribution to journalArticlepeer-review

    22 Scopus citations
  • Feasibility of large-scale genomic testing to facilitate enrollment onto genomically matched clinical trials

    Meric-Bernstam, F., Brusco, L., Shaw, K., Horombe, C., Kopetz, S., Davies, M. A., Routbort, M., Piha-Paul, S. A., Janku, F., Ueno, N., Hong, D., De Groot, J., Ravi, V., Li, Y., Luthra, R., Patel, K., Broaddus, R., Mendelsohn, J. & Mills, G. B., Sep 1 2015, In: Journal of Clinical Oncology. 33, 25, p. 2753-2762 10 p.

    Research output: Contribution to journalArticlepeer-review

    252 Scopus citations
  • Functional consequence of the MET-T1010I polymorphism in breast cancer

    Liu, S., Meric-Bernstam, F., Parinyanitikul, N., Wang, B., Eterovic, A. K., Zheng, X., Gagea, M., Chavez-MacGregor, M., Ueno, N. T., Lei, X., Zhou, W., Nair, L., Tripathy, D., Brown, P. H., Hortobagyi, G. N., Chen, K., Mendelsohn, J., Mills, G. B. & Gonzalez-Angulo, A. M., 2015, In: Oncotarget. 6, 5, p. 2604-2614 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations