• Source: Scopus
  • Calculated based on no. of publications stored in Pure and citations from Scopus
1976 …2022

Research activity per year

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Search results

  • 2017

    Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas

    Huo, D., Hu, H., Rhie, S. K., Gamazon, E. R., Cherniack, A. D., Liu, J., Yoshimatsu, T. F., Pitt, J. J., Hoadley, K. A., Troester, M., Ru, Y., Lichtenberg, T., Sturtz, L. A., Shelley, C. S., Benz, C. C., Mills, G. B., Laird, P. W., Shriver, C. D., Perou, C. M. & Olopade, O. I., Dec 1 2017, In: JAMA Oncology. 3, 12, p. 1654-1662 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    129 Scopus citations
  • Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

    The Cancer Genome Atlas Research Network, Nov 2 2017, In: Cell. 171, 4, p. 950-965.e28

    Research output: Contribution to journalArticlepeer-review

    Open Access
    415 Scopus citations
  • Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

    The Cancer Genome Atlas Research Network, Jun 15 2017, In: Cell. 169, 7, p. 1327-1341.e23

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1005 Scopus citations
  • Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

    Robertson, A. G., Kim, J., Al-Ahmadie, H., Bellmunt, J., Guo, G., Cherniack, A. D., Hinoue, T., Laird, P. W., Hoadley, K. A., Akbani, R., Castro, M. A. A., Gibb, E. A., Kanchi, R. S., Gordenin, D. A., Shukla, S. A., Sanchez-Vega, F., Hansel, D. E., Czerniak, B. A., Reuter, V. E., Su, X. & 153 others, de Sa Carvalho, B., Chagas, V. S., Mungall, K. L., Sadeghi, S., Pedamallu, C. S., Lu, Y., Klimczak, L. J., Zhang, J., Choo, C., Ojesina, A. I., Bullman, S., Leraas, K. M., Lichtenberg, T. M., Wu, C. J., Schultz, N., Getz, G., Meyerson, M., Mills, G. B., McConkey, D. J., Albert, M., Alexopoulou, I., Ally, A., Antic, T., Aron, M., Balasundaram, M., Bartlett, J., Baylin, S. B., Beaver, A., Birol, I., Boice, L., Bootwalla, M. S., Bowen, J., Bowlby, R., Brooks, D., Broom, B. M., Bshara, W., Burks, E., Cárcano, F. M., Carlsen, R., Carvalho, A. L., Castle, E. P., Castro, P., Catto, J. W., Chesla, D. W., Chuah, E., Chudamani, S., Cortessis, V. K., Cottingham, S. L., Crain, D., Curley, E., Daneshmand, S., Demchok, J. A., Dhalla, N., Djaladat, H., Eckman, J., Egea, S. C., Engel, J., Felau, I., Ferguson, M. L., Gardner, J., Gastier-Foster, J. M., Gerken, M., Gomez-Fernandez, C. R., Harr, J., Hartmann, A., Herbert, L. M., Ho, T. H., Holt, R. A., Hutter, C. M., Jones, S. J. M., Jorda, M., Kahnoski, R. J., Kasaian, K., Kwiatkowski, D. J., Lai, P. H., Lane, B. R., Lerner, S. P., Liu, J., Lolla, L., Lotan, Y., Lucchesi, F. R., Ma, Y., Machado, R. D., Maglinte, D. T., Mallery, D., Marra, M. A., Martin, S. E., Mayo, M., Meraney, A., Moinzadeh, A., Moore, R. A., Mora Pinero, E. M., Morris, S., Morrison, C., Mungall, A. J., Myers, J. B., Naresh, R., O'Donnell, P. H., Parekh, D. J., Parfitt, J., Paulauskis, J. D., Sekhar Pedamallu, C., Penny, R. J., Pihl, T., Porten, S., Quintero-Aguilo, M. E., Ramirez, N. C., Rathmell, W. K., Rieger-Christ, K., Saller, C., Salner, A., Sandusky, G., Scapulatempo-Neto, C., Schein, J. E., Schuckman, A. K., Shelton, C., Shelton, T., Simko, J., Singh, P., Sipahimalani, P., Smith, N. D., Sofia, H. J., Sorcini, A., Stanton, M. L., Steinberg, G. D., Stoehr, R., Su, X., Sullivan, T., Sun, Q., Tam, A., Tarnuzzer, R., Tarvin, K., Taubert, H., Thiessen, N., Thorne, L., Tse, K., Tucker, K., Van Den Berg, D. J., van Kessel, K. E., Wach, S., Wan, Y., Wang, Z., Weinstein, J. N., Weisenberger, D. J., Wise, L., Wong, T., Wu, Y., Yang, L., Zach, L. A., Zenklusen, J. C., Zhang, J., Zmuda, E. & Zwarthoff, E. C., Oct 19 2017, In: Cell. 171, 3, p. 540-556.e25

    Research output: Contribution to journalArticlepeer-review

    Open Access
    954 Scopus citations
  • Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma

    Fishbein, L., Leshchiner, I., Walter, V., Danilova, L., Robertson, A. G., Johnson, A. R., Lichtenberg, T. M., Murray, B. A., Ghayee, H. K., Else, T., Ling, S., Jefferys, S. R., de Cubas, A. A., Wenz, B., Korpershoek, E., Amelio, A. L., Makowski, L., Rathmell, W. K., Gimenez-Roqueplo, A. P., Giordano, T. J. & 187 others, Asa, S. L., Tischler, A. S., Akbani, R., Ally, A., Amar, L., Arachchi, H., Auchus, R. J., Auman, J. T., Baertsch, R., Balasundaram, M., Balu, S., Bartsch, D. K., Baudin, E., Bauer, T., Beaver, A., Benz, C., Beroukhim, R., Beuschlein, F., Bodenheimer, T., Boice, L., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Carter, S., Cassol, C. A., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cope, L., Crain, D., Curley, E., de Krijger, R. R., Demchok, J. A., Deutschbein, T., Dhalla, N., Dimmock, D., Dinjens, W. N. M., Eng, C., Eschbacher, J., Fassnacht, M., Felau, I., Feldman, M., Ferguson, M. L., Fiddes, I., Frazer, S., Gabriel, S. B., Gardner, J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Geurts, J., Goldman, M., Graim, K., Gupta, M., Haan, D., Hahner, S., Hantel, C., Haussler, D., Hayes, D. N., Heiman, D. I., Hoadley, K. A., Holt, R. A., Hoyle, A. P., Huang, M., Hunt, B., Hutter, C. M., Jones, S. J. M., Jones, C. D., Kasaian, K., Kebebew, E., Kim, J., Kimes, P., Knijnenburg, T., Lander, E., Lawrence, M. S., Lechan, R., Lee, D., Leraas, K. M., Lerario, A., Lin, P., Liu, J., LiVolsi, V. A., Lolla, L., Lotan, Y., Lu, Y., Ma, Y., Maison, N., Mallery, D., Mannelli, M., Marquard, J., Marra, M. A., Matthew, T., Mayo, M., Méatchi, T., Meng, S., Merino, M. J., Mete, O., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Morozova, O., Morris, S., Mose, L. E., Mungall, A. J., Naresh, R., Nathanson, K. L., Newton, Y., Ng, S., Ni, Y., Noble, M. S., Nwariaku, F., Pacak, K., Parker, J. S., Paul, E., Penny, R., Perou, C. M., Perou, A. H., Pihl, T., Powers, J., Rabaglia, J., Radenbaugh, A., Ramirez, N. C., Rao, A., Riester, A., Roach, J., Sadeghi, S., Saksena, G., Salama, S., Saller, C., Sandusky, G., Sbiera, S., Schein, J. E., Schumacher, S. E., Shelton, C., Shelton, T., Sheth, M., Shi, Y., Shih, J., Shmulevich, I., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Sokolov, A., Soloway, M. G., Sougnez, C., Stuart, J., Sun, C., Swatloski, T., Tam, A., Tan, D., Tarnuzzer, R., Tarvin, K., Thiessen, N., Thorne, L. B., Timmers, H. J., Tse, K., Uzunangelov, V., van Berkel, A., Veluvolu, U., Vicha, A., Voet, D., Waldmann, J., Wan, Y., Wang, Z., Wang, T. S., Weaver, J., Weinstein, J. N., Weismann, D., Wilkerson, M. D., Wise, L., Wong, T., Wong, C., Wu, Y., Yang, L., Zelinka, T., Zenklusen, J. C., Zhang, J., Zhang, W., Zhu, J., Zinzindohoué, F. & Zmuda, E., Feb 13 2017, In: Cancer Cell. 31, 2, p. 181-193 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    352 Scopus citations
  • Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

    Hill, S. M., Nesser, N. K., Johnson-Camacho, K., Jeffress, M., Johnson, A., Boniface, C., Spencer, S. E. F., Lu, Y., Heiser, L. M., Lawrence, Y., Pande, N. T., Korkola, J. E., Gray, J. W., Mills, G. B., Mukherjee, S. & Spellman, P. T., Jan 25 2017, In: Cell Systems. 4, 1, p. 73-83.e10

    Research output: Contribution to journalArticlepeer-review

    Open Access
    20 Scopus citations
  • Correction: Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer (PLoS ONE (2015) 10:7 (e0133219) DOI: 10.1371/journal.pone.0133219)

    Korkola, J. E., Collisson, E. A., Heiser, L. M., Oates, C., Bayani, N., Itani, S., Esch, A., Thompson, W., Griffith, O. L., Wang, N., Kuo, W. L., Cooper, B., Billig, J., Ziyad, S., Hung, J. L., Jakkula, L., Feiler, H., Lu, Y., Mills, G. B., Spellman, P. T. & 3 others, Tomlin, C., Mukherjee, S. & Gray, J. W., Oct 2017, In: PloS one. 12, 10, e0186551.

    Research output: Contribution to journalComment/debatepeer-review

    Open Access
  • CTNNB1 (beta-catenin) mutation identifies low grade, early stage endometrial cancer patients at increased risk of recurrence

    Kurnit, K. C., Kim, G. N., Fellman, B. M., Urbauer, D. L., Mills, G. B., Zhang, W. & Broaddus, R. R., Jul 1 2017, In: Modern Pathology. 30, 7, p. 1032-1041 10 p.

    Research output: Contribution to journalArticlepeer-review

    130 Scopus citations
  • Development and validation of an ultradeep next-generation sequencing assay for testing of plasma cell-free DNA from patients with advanced cancer

    Janku, F., Zhang, S., Waters, J., Liu, L., Huang, H. J., Subbiah, V., Hong, D. S., Karp, D. D., Fu, S., Cai, X., Ramzanali, N. M., Madwani, K., Cabrilo, G., Andrews, D. L., Zhao, Y., Javle, M., Kopetz, E. S., Luthra, R., Kim, H. J., Gnerre, S. & 11 others, Satya, R. V., Chuang, H. Y., Kruglyak, K. M., Toung, J., Zhao, C., Shen, R., Heymach, J. V., Meric-Bernstam, F., Mills, G. B., Fan, J. B. & Salathia, N. S., Sep 15 2017, In: Clinical Cancer Research. 23, 18, p. 5648-5656 9 p.

    Research output: Contribution to journalArticlepeer-review

    38 Scopus citations
  • Engineering and functional characterization of fusion genes identifies novel oncogenic drivers of cancer

    Lu, H., Villafane, N., Dogruluk, T., Grzeskowiak, C. L., Kong, K., Tsang, Y. H., Zagorodna, O., Pantazi, A., Yang, L., Neill, N. J., Kim, Y. W., Creighton, C. J., Verhaak, R. G., Mills, G. B., Park, P. J., Kucherlapati, R. & Scott, K. L., Jul 1 2017, In: Cancer Research. 77, 13, p. 3502-3512 11 p.

    Research output: Contribution to journalArticlepeer-review

    26 Scopus citations
  • Epigenetic regulation of KPC1 ubiquitin ligase affects the NF-κB pathway in melanoma

    Iida, Y., Ciechanover, A., Marzese, D. M., Hata, K., Bustos, M., Ono, S., Wang, J., Salomon, M. P., Tran, K., Lam, S., Hsu, S., Nelson, N., Kravtsova-Ivantsiv, Y., Mills, G. B., Davies, M. A. & Hoon, D. S. B., Aug 15 2017, In: Clinical Cancer Research. 23, 16, p. 4831-4842 12 p.

    Research output: Contribution to journalArticlepeer-review

    20 Scopus citations
  • Erratum: Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles (Cell Reports (2017) 18(11) (2780–2794) (S2211124717302140) (10.1016/j.celrep.2017.02.033))

    The Cancer Genome Atlas Network, Jun 27 2017, In: Cell Reports. 19, 13, p. 2878-2880 3 p.

    Research output: Contribution to journalComment/debatepeer-review

    Open Access
    90 Scopus citations
  • Establishment of patient-derived tumor xenograft models of epithelial ovarian cancer for preclinical evaluation of novel therapeutics

    Liu, J. F., Palakurthi, S., Zeng, Q., Zhou, S., Ivanova, E., Huang, W., Zervantonakis, I. K., Selfors, L. M., Shen, Y., Pritchard, C. C., Zheng, M., Adleff, V., Papp, E., Piao, H., Novak, M., Fotheringham, S., Wulf, G. M., English, J., Kirschmeier, P. T., Velculescu, V. E. & 6 others, Paweletz, C., Mills, G. B., Livingston, D. M., Brugge, J. S., Matulonis, U. A. & Drapkin, R., Mar 1 2017, In: Clinical Cancer Research. 23, 5, p. 1263-1273 11 p.

    Research output: Contribution to journalArticlepeer-review

    65 Scopus citations
  • Explore, visualize, and analyze functional cancer proteomic data using the cancer proteome atlas

    Li, J., Akbani, R., Zhao, W., Lu, Y., Weinstein, J. N., Mills, G. B. & Liang, H., Nov 1 2017, In: Cancer Research. 77, 21, p. e51-e54

    Research output: Contribution to journalArticlepeer-review

    46 Scopus citations
  • Functional proteomic characterization of cancer cell lines

    Zhao, W., Li, J. & Mills, G., Jan 1 2017, In: Oncoscience. 4, 5-6, p. 41-42 2 p.

    Research output: Contribution to journalEditorialpeer-review

    1 Scopus citations
  • Functional variomics and network perturbation: Connecting genotype to phenotype in cancer

    Yi, S., Lin, S., Li, Y., Zhao, W., Mills, G. B. & Sahni, N., Jul 1 2017, In: Nature Reviews Genetics. 18, 7, p. 395-410 16 p.

    Research output: Contribution to journalReview articlepeer-review

    55 Scopus citations
  • Genomic analysis of exceptional responder to regorafenib in treatment-refractory metastatic rectal cancer: A case report and review of the literature

    Korphaisarn, K., Loree, J. M., Nguyen, V., Coulson, R., Holla, V., Litzenburger, B. C., Chen, K., Mills, G. B., Maru, D. M., Meric-Bernstan, F., Shaw, K. R. M. & Kopetz, S., 2017, In: Oncotarget. 8, 34, p. 57882-57888 7 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • Identifying abundant immunotherapy and other targets in solid tumors integrating RNA-seq and mass spectrometry proteomics data sets

    Zhao, W., Fitzgibbon, M., Bergan, L., Clegg, N., Crispin, D., Mills, G. B. & Mcintosh, M., 2017, In: Cancer Journal (United States). 23, 2, p. 108-114 7 p.

    Research output: Contribution to journalReview articlepeer-review

    1 Scopus citations
  • Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm

    McGrail, D. J., Lin, C. C. J., Garnett, J., Liu, Q., Mo, W., Dai, H., Lu, Y., Yu, Q., Ju, Z., Yin, J., Vellano, C. P., Hennessy, B., Mills, G. B. & Lin, S. Y., Dec 1 2017, In: npj Systems Biology and Applications. 3, 1, 8.

    Research output: Contribution to journalArticlepeer-review

    35 Scopus citations
  • Integrated genomic and molecular characterization of cervical cancer

    The Cancer Genome Atlas Research Network, Mar 16 2017, In: Nature. 543, 7645, p. 378-384 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    720 Scopus citations
  • Integrated genomic characterization of oesophageal carcinoma

    The Cancer Genome Atlas Research Network, Jan 12 2017, In: Nature. 541, 7636, p. 169-174 6 p.

    Research output: Contribution to journalArticlepeer-review

    896 Scopus citations
  • Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

    Raphael, B. J., Hruban, R. H., Aguirre, A. J., Moffitt, R. A., Yeh, J. J., Stewart, C., Robertson, A. G., Cherniack, A. D., Gupta, M., Getz, G., Gabriel, S. B., Meyerson, M., Cibulskis, C., Fei, S. S., Hinoue, T., Shen, H., Laird, P. W., Ling, S., Lu, Y., Mills, G. B. & 251 others, Akbani, R., Loher, P., Londin, E. R., Rigoutsos, I., Telonis, A. G., Gibb, E. A., Goldenberg, A., Mezlini, A. M., Hoadley, K. A., Collisson, E., Lander, E., Murray, B. A., Hess, J., Rosenberg, M., Bergelson, L., Zhang, H., Cho, J., Tiao, G., Kim, J., Livitz, D., Leshchiner, I., Reardon, B., Van Allen, E., Kamburov, A., Beroukhim, R., Saksena, G., Schumacher, S. E., Noble, M. S., Heiman, D. I., Gehlenborg, N., Kim, J., Lawrence, M. S., Adsay, V., Petersen, G., Klimstra, D., Bardeesy, N., Leiserson, M. D. M., Bowlby, R., Kasaian, K., Birol, I., Mungall, K. L., Sadeghi, S., Weinstein, J. N., Spellman, P. T., Liu, Y., Amundadottir, L. T., Tepper, J., Singhi, A. D., Dhir, R., Paul, D., Smyrk, T., Zhang, L., Kim, P., Bowen, J., Frick, J., Gastier-Foster, J. M., Gerken, M., Lau, K., Leraas, K. M., Lichtenberg, T. M., Ramirez, N. C., Renkel, J., Sherman, M., Wise, L., Yena, P., Zmuda, E., Shih, J., Ally, A., Balasundaram, M., Carlsen, R., Chu, A., Chuah, E., Clarke, A., Dhalla, N., Holt, R. A., Jones, S. J. M., Lee, D., Ma, Y., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Tse, K., Wong, T., Brooks, D., Auman, J. T., Balu, S., Bodenheimer, T., Hayes, D. N., Hoyle, A. P., Jefferys, S. R., Jones, C. D., Meng, S., Mieczkowski, P. A., Mose, L. E., Perou, C. M., Perou, A. H., Roach, J., Shi, Y., Simons, J. V., Skelly, T., Soloway, M. G., Tan, D., Veluvolu, U., Parker, J. S., Wilkerson, M. D., Korkut, A., Senbabaoglu, Y., Burch, P., McWilliams, R., Chaffee, K., Oberg, A., Zhang, W., Gingras, M. C., Wheeler, D. A., Xi, L., Albert, M., Bartlett, J., Sekhon, H., Stephen, Y., Howard, Z., Judy, M., Breggia, A., Shroff, R. T., Chudamani, S., Liu, J., Lolla, L., Naresh, R., Pihl, T., Sun, Q., Wan, Y., Wu, Y., Jennifer, S., Roggin, K., Becker, K. F., Behera, M., Bennett, J., Boice, L., Burks, E., Carlotti Junior, C. G., Chabot, J., Pretti da Cunha Tirapelli, D., Sebastião dos Santos, J., Dubina, M., Eschbacher, J., Huang, M., Huelsenbeck-Dill, L., Jenkins, R., Karpov, A., Kemp, R., Lyadov, V., Maithel, S., Manikhas, G., Montgomery, E., Noushmehr, H., Osunkoya, A., Owonikoko, T., Paklina, O., Potapova, O., Ramalingam, S., Rathmell, W. K., Rieger-Christ, K., Saller, C., Setdikova, G., Shabunin, A., Sica, G., Su, T., Sullivan, T., Swanson, P., Tarvin, K., Tavobilov, M., Thorne, L. B., Urbanski, S., Voronina, O., Wang, T., Crain, D., Curley, E., Gardner, J., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, C., Shelton, T., Janssen, K. P., Bathe, O., Bahary, N., Slotta-Huspenina, J., Johns, A., Hibshoosh, H., Hwang, R. F., Sepulveda, A., Radenbaugh, A., Baylin, S. B., Berrios, M., Bootwalla, M. S., Holbrook, A., Lai, P. H., Maglinte, D. T., Mahurkar, S., Triche, T. J., Van Den Berg, D. J., Weisenberger, D. J., Chin, L., Kucherlapati, R., Kucherlapati, M., Pantazi, A., Park, P., Saksena, G., Voet, D., Lin, P., Frazer, S., Defreitas, T., Meier, S., Chin, L., Kwon, S. Y., Kim, Y. H., Park, S. J., Han, S. S., Kim, S. H., Kim, H., Furth, E., Tempero, M., Sander, C., Biankin, A., Chang, D., Bailey, P., Gill, A., Kench, J., Grimmond, S., Johns, A., Cancer Genome Initiative (APGI, A. P., Postier, R., Zuna, R., Sicotte, H., Demchok, J. A., Ferguson, M. L., Hutter, C. M., Mills Shaw, K. R., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zhang, J., Felau, I. & Zenklusen, J. C., Aug 14 2017, In: Cancer Cell. 32, 2, p. 185-203.e13

    Research output: Contribution to journalArticlepeer-review

    Open Access
    842 Scopus citations
  • Integrated Molecular Characterization of Uterine Carcinosarcoma

    Cherniack, A. D., Shen, H., Walter, V., Stewart, C., Murray, B. A., Bowlby, R., Hu, X., Ling, S., Soslow, R. A., Broaddus, R. R., Zuna, R. E., Robertson, G., Laird, P. W., Kucherlapati, R., Mills, G. B., Akbani, R., Ally, A., Auman, J. T., Balasundaram, M., Balu, S. & 130 others, Baylin, S. B., Beroukhim, R., Bodenheimer, T., Bogomolniy, F., Boice, L., Bootwalla, M. S., Bowen, J., Broaddus, R., Brooks, D., Carlsen, R., Cho, J., Chuah, E., Chudamani, S., Cibulskis, K., Cline, M., Dao, F., David, M., Demchok, J. A., Dhalla, N., Dowdy, S., Felau, I., Ferguson, M. L., Frazer, S., Frick, J., Gabriel, S., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Gupta, M., Haussler, D., Hayes, D. N., Heiman, D. I., Hess, J., Hoadley, K. A., Hoffmann, R., Holt, R. A., Hoyle, A. P., Huang, M., Hutter, C. M., Jefferys, S. R., Jones, S. J. M., Jones, C. D., Kanchi, R. S., Kandoth, C., Kasaian, K., Kerr, S., Kim, J., Lai, P. H., Lander, E., Lawrence, M. S., Lee, D., Leraas, K. M., Leshchiner, I., Levine, D. A., Lichtenberg, T. M., Lin, P., Liu, J., Liu, W., Liu, Y., Lolla, L., Lu, Y., Ma, Y., Maglinte, D. T., Marra, M. A., Mayo, M., Meng, S., Meyerson, M., Mieczkowski, P. A., Moore, R. A., Mose, L. E., Mungall, A. J., Mungall, K., Naresh, R., Noble, M. S., Olvera, N., Parker, J. S., Perou, C. M., Perou, A. H., Pihl, T., Radenbaugh, A. J., Ramirez, N. C., Rathmell, W. K., Roach, J., Robertson, A. G., Sadeghi, S., Saksena, G., Salvesen, H. B., Schein, J. E., Schumacher, S. E., Sheth, M., Shi, Y., Shih, J., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Soloway, M. G., Sougnez, C., Sun, C., Tam, A., Tan, D., Tarnuzzer, R., Thiessen, N., Thorne, L. B., Tse, K., Tseng, J., Van Den Berg, D. J., Veluvolu, U., Verhaak, R. G. W., Voet, D., von Bismarck, A., Wan, Y., Wang, Z., Wang, C., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Winterhoff, B., Wise, L., Wong, T., Wu, Y., Yang, L., Zenklusen, J. C., Zhang, J., Zhang, H., Zhang, W., Zhu, J. C., Zmuda, E. & Zhang, J., Mar 13 2017, In: Cancer Cell. 31, 3, p. 411-423 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    202 Scopus citations
  • Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

    Robertson, A. G., Shih, J., Yau, C., Gibb, E. A., Oba, J., Mungall, K. L., Hess, J. M., Uzunangelov, V., Walter, V., Danilova, L., Lichtenberg, T. M., Kucherlapati, M., Kimes, P. K., Tang, M., Penson, A., Babur, O., Akbani, R., Bristow, C. A., Hoadley, K. A., Iype, L. & 150 others, Chang, M. T., Abdel-Rahman, M. H., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., Benz, C., Beroukhim, R., Birol, I., Bodenheimer, T., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Cebulla, C. M., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cibulskis, C., Cibulskis, K., Cope, L., Coupland, S. E., Defreitas, T., Demchok, J. A., Desjardins, L., Dhalla, N., Esmaeli, B., Felau, I., Ferguson, M. L., Frazer, S., Gabriel, S. B., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Gershenwald, J. E., Getz, G., Griewank, K. G., Grimm, E. A., Hayes, D. N., Hegde, A. M., Heiman, D. I., Helsel, C., Hobensack, S., Holt, R. A., Hoyle, A. P., Hu, X., Hutter, C. M., Jager, M. J., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Kandoth, C., Kasaian, K., Kim, J., Kucherlapati, R., Lander, E., Lawrence, M. S., Lazar, A. J., Lee, S., Leraas, K. M., Lin, P., Liu, J., Liu, W., Lolla, L., Lu, Y., Ma, Y., Mahadeshwar, H. S., Mariani, O., Marra, M. A., Mayo, M., Meier, S., Meng, S., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Naresh, R., Noble, M. S., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Pihl, T., Pilarski, R., Protopopov, A., Radenbaugh, A., Rai, K., Ramirez, N. C., Ren, X., Reynolds, S. M., Roach, J., Roman-Roman, S., Roszik, J., Sadeghi, S., Saksena, G., Sastre, X., Schadendorf, D., Schein, J. E., Schoenfield, L., Schumacher, S. E., Seidman, J., Seth, S., Sethi, G., Sheth, M., Shi, Y., Shields, C., Shmulevich, I., Simons, J. V., Singh, A. D., Sipahimalani, P., Skelly, T., Sofia, H., Soloway, M. G., Song, X., Stern, M. H., Stuart, J., Sun, Q., Sun, H., Tam, A., Tan, D., Tang, J., Tarnuzzer, R., Taylor, B. S., Thiessen, N., Thorsson, V., Tse, K., Veluvolu, U., Verhaak, R. G. W., Voet, D., Wan, Y., Wang, Z., Weinstein, J. N., Wilkerson, M. D., Williams, M. D., Wise, L., Woodman, S. E., Wong, T., Wu, Y., Yang, L., Yang, L., Zenklusen, J. C., Zhang, J., Zhang, H. & Zmuda, E., Aug 14 2017, In: Cancer Cell. 32, 2, p. 204-220.e15

    Research output: Contribution to journalArticlepeer-review

    Open Access
    383 Scopus citations
  • Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome

    Aure, M. R., Vitelli, V., Jernström, S., Kumar, S., Krohn, M., Due, E. U., Haukaas, T. H., Leivonen, S. K., Vollan, H. K. M., Lüders, T., Rødland, E., Vaske, C. J., Zhao, W., Møller, E. K., Nord, S., Giskeødegård, G. F., Bathen, T. F., Caldas, C., Tramm, T., Alsner, J. & 26 others, Overgaard, J., Geisler, J., Bukholm, I. R. K., Naume, B., Schlichting, E., Sauer, T., Mills, G. B., Kåresen, R., Mælandsmo, G. M., Lingjærde, O. C., Frigessi, A., Kristensen, V. N., Børresen-Dale, A. L., Sahlberg, K. K., Borgen, E., Engebråten, O., Fodstad, Ø., Fritzman, B., Garred, Ø., Geitvik, G. A., Langerød, A., Hofvind, S., Russnes, H. G., Skjerven, H. K., Sørlie, T. & OSBREAC, Mar 29 2017, In: Breast Cancer Research. 19, 1, 44.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    50 Scopus citations
  • Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles

    CONSORTIA, Mar 14 2017, In: Cell Reports. 18, 11, p. 2780-2794 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    239 Scopus citations
  • Loss-of-function screens of druggable targetome against cancer stem-like cells

    Song, M., Lee, H., Nam, M. H., Jeong, E., Kim, S., Hong, Y., Kim, N., Yim, H. Y., Yoo, Y. J., Kim, J. S., Kim, J. S., Cho, Y. Y., Mills, G. B., Kim, W. Y. & Yoon, S., Feb 2017, In: FASEB Journal. 31, 2, p. 625-935 311 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    20 Scopus citations
  • Molecular heterogeneity at the network level: High-dimensional testing, clustering and a TCGA case study

    Städler, N., Dondelinger, F., Hill, S. M., Akbani, R., Lu, Y., Mills, G. B. & Mukherjee, S., Sep 15 2017, In: Bioinformatics. 33, 18, p. 2890-2896 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    11 Scopus citations
  • Multiplatform-based molecular subtypes of non-small-cell lung cancer

    Chen, F., Zhang, Y., Parra, E., Rodriguez, J., Behrens, C., Akbani, R., Lu, Y., Kurie, J. M., Gibbons, D. L., Mills, G. B., Wistuba, I. I. & Creighton, C. J., Mar 1 2017, In: Oncogene. 36, 10, p. 1384-1393 10 p.

    Research output: Contribution to journalArticlepeer-review

    72 Scopus citations
  • Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer

    Kang, M. H., Jeong, K. J., Kim, W. Y., Lee, H. J., Gong, G., Suh, N., Gyrffy, B., Kim, S., Jeong, S. Y., Mills, G. B. & Park, Y. Y., Mar 23 2017, In: Oncogene. 36, 12, p. 1745-1752 8 p.

    Research output: Contribution to journalArticlepeer-review

    41 Scopus citations
  • Neomorphic mutations create therapeutic challenges in cancer

    Takiar, V., Ip, C. K. M., Gao, M., Mills, G. B. & Cheung, L. W. T., Mar 23 2017, In: Oncogene. 36, 12, p. 1607-1618 12 p.

    Research output: Contribution to journalReview articlepeer-review

    16 Scopus citations
  • Next-Generation Sequencing and Result Interpretation in Clinical Oncology: Challenges of Personalized Cancer Therapy

    Khotskaya, Y. B., Mills, G. B. & Mills Shaw, K. R., Jan 14 2017, In: Annual review of medicine. 68, p. 113-125 13 p.

    Research output: Contribution to journalArticlepeer-review

    24 Scopus citations
  • Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo

    Zoeller, J. J., Bronson, R. T., Selfors, L. M., Mills, G. B. & Brugge, J. S., Dec 1 2017, In: npj Breast Cancer. 3, 1, 18.

    Research output: Contribution to journalArticlepeer-review

    14 Scopus citations
  • Oncogenic RAS Regulates Long Noncoding RNA Orilnc1 in Human Cancer

    Zhang, D., Zhang, G., Hu, X., Wu, L., Feng, Y., He, S., Zhang, Y., Hu, Z., Yang, L., Tian, T., Xu, W., Wei, Z., Lu, Y., Flaherty, K. T., Zhong, X., Mills, G. B., Gimotty, P. A., Xu, X., Herlyn, M. & Zhang, L., Jul 15 2017, In: Cancer Research. 77, 14, p. 3745-3757 13 p.

    Research output: Contribution to journalArticlepeer-review

    21 Scopus citations
  • PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas

    Lu, H., Liu, S., Zhang, G., Wu, B., Zhu, Y., Frederick, D. T., Hu, Y., Zhong, W., Randell, S., Sadek, N., Zhang, W., Chen, G., Cheng, C., Zeng, J., Wu, L. W., Zhang, J., Liu, X., Xu, W., Krepler, C., Sproesser, K. & 21 others, Xiao, M., Miao, B., Liu, J., Song, C. D., Liu, J. Y., Karakousis, G. C., Schuchter, L. M., Lu, Y., Mills, G., Cong, Y., Chernoff, J., Guo, J., Boland, G. M., Sullivan, R. J., Wei, Z., Field, J., Amaravadi, R. K., Flaherty, K. T., Herlyn, M., Xu, X. & Guo, W., Oct 5 2017, In: Nature. 550, 7674, p. 133-136 4 p.

    Research output: Contribution to journalArticlepeer-review

    96 Scopus citations
  • Patient-derived xenograft models of ovarian/gynecologic tumors

    Liang, L., Mercado-Uribe, I., Niu, N., Jiang, Y., Cheng, W., Zhang, J., Mills, G. B., Scott, C., Sood, A. K. & Liu, J., 2017, Patient Derived Tumor Xenograft Models: Promise, Potential and Practice. Elsevier Inc., p. 257-271 15 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • Personalized cancer therapy: A publicly available precision oncology resource

    Kurnit, K. C., Bailey, A. M., Zeng, J., Johnson, A. M., Shufean, M. A., Brusco, L., Litzenburger, B. C., Sanchez, N. S., Khotskaya, Y. B., Holla, V., Simpson, A., Mills, G. B., Mendelsohn, J., Bernstam, E., Shaw, K. & Meric-Bernstam, F., Nov 1 2017, In: Cancer Research. 77, 21, p. e123-e126

    Research output: Contribution to journalArticlepeer-review

    26 Scopus citations
  • Phase I dose escalation study of the PI3kinase pathway inhibitor BKM120 and the oral poly (ADP ribose) polymerase (PARP) inhibitor olaparib for the treatment of high-grade serous ovarian and breast cancer

    Matulonis, U. A., Wulf, G. M., Barry, W. T., Birrer, M., Westin, S. N., Farooq, S., Bell-McGuinn, K. M., Obermayer, E., Whalen, C., Spagnoletti, T., Luo, W., Liu, H., Hok, R. C., Aghajanian, C., Solit, D. B., Mills, G. B., Taylor, B. S., Won, H., Berger, M. F., Palakurthi, S. & 3 others, Liu, J., Cantley, L. C. & Winer, E., Mar 2017, In: Annals of Oncology. 28, 3, p. 512-518 7 p.

    Research output: Contribution to journalArticlepeer-review

    123 Scopus citations
  • PIK3CA exon9 mutations associate with reduced survival, and are highly concordant between matching primary tumors and metastases in endometrial cancer

    Mjos, S., Werner, H. M. J., Birkeland, E., Holst, F., Berg, A., Halle, M. K., Tangen, I. L., Kusonmano, K., Mauland, K. K., Oyan, A. M., Kalland, K. H., Lewis, A. E., Mills, G. B., Krakstad, C., Trovik, J., Salvesen, H. B. & Hoivik, E. A., Dec 1 2017, In: Scientific Reports. 7, 1, 10240.

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations
  • Precision oncology: Neither a silver bullet nor a dream

    Sánchez, N. S., Mills, G. B. & Shaw, K. R. M., Nov 2017, In: Pharmacogenomics. 18, 16, p. 1525-1539 15 p.

    Research output: Contribution to journalReview articlepeer-review

    17 Scopus citations
  • Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival

    Clarke, C. N., Lee, M. S., Wei, W., Manyam, G., Jiang, Z. Q., Lu, Y., Morris, J., Broom, B., Menter, D., Vilar-Sanchez, E., Raghav, K., Eng, C., Chang, G. J., Simon, I., Bernards, R., Overman, M., Mills, G. B., Maru, D. & Kopetz, S., Dec 1 2017, In: Annals of surgical oncology. 24, 13, p. 4051-4058 8 p.

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations
  • Proteomic profiling of endometrioid endometrial cancer reveals differential expression of hormone receptors and MAPK signaling proteins in obese versus non-obese patients

    Mauland, K. K., Ju, Z., Tangen, I. L., Berg, A., Kalland, K. H., Øyan, A. M., Bjørge, L., Westin, S. N., Krakstad, C., Trovik, J., Mills, G. B., Hoivik, E. A. & Werner, H. M. J., 2017, In: Oncotarget. 8, 63, p. 106989-107001 13 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • Randomized, placebo-controlled window trial of EGFR, Src, or combined blockade in head and neck cancer

    Bauman, J. E., Duvvuri, U., Gooding, W. E., Rath, T. J., Gross, N. D., Song, J., Jimeno, A., Yarbrough, W. G., Johnson, F. M., Wang, L., Chiosea, S., Sen, M., Kass, J., Johnson, J. T., Ferris, R. L., Kim, S., Hirsch, F. R., Ellison, K., Flaherty, J. T., Mills, G. B. & 1 others, Grandis, J. R., Mar 23 2017, In: JCI Insight. 2, 6, p. e90449

    Research output: Contribution to journalArticlepeer-review

    Open Access
    26 Scopus citations
  • Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers

    Sun, C., Fang, Y., Yin, J., Chen, J., Ju, Z., Zhang, D., Chen, X., Vellano, C. P., Jeong, K. J., Ng, P. K. S., Eterovic, A. K. B., Bhola, N. H., Lu, Y., Westin, S. N., Grandis, J. R., Lin, S. Y., Scott, K. L., Peng, G., Brugge, J. & Mills, G. B., May 31 2017, In: Science translational medicine. 9, 392, aal5148.

    Research output: Contribution to journalArticlepeer-review

    110 Scopus citations
  • RCP induces Slug expression and cancer cell invasion by stabilizing β1 integrin

    Hwang, M. H., Cho, K. H., Jeong, K. J., Park, Y. Y., Kim, J. M., Yu, S. L., Park, C. G., Mills, G. B. & Lee, H. Y., Feb 23 2017, In: Oncogene. 36, 8, p. 1102-1111 10 p.

    Research output: Contribution to journalArticlepeer-review

    26 Scopus citations
  • Role of RPL39 in Metaplastic Breast Cancer

    Dave, B., Gonzalez, D. D., Liu, Z. B., Li, X., Wong, H., Granados, S., Ezzedine, N. E., Sieglaff, D. H., Ensor, J. E., Miller, K. D., Radovich, M., KarinaEtrovic, A., Gross, S. S., Elemento, O., Mills, G. B., Gilcrease, M. Z. & Chang, J. C., Jun 1 2017, In: Journal of the National Cancer Institute. 109, 6, djw292.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    42 Scopus citations
  • Sarcomatoid renal cell carcinoma has a distinct molecular pathogenesis, driver mutation profile, and transcriptional landscape

    Wang, Z., Kim, T. B., Peng, B., Karam, J., Creighton, C., Joon, A., Kawakami, F., Trevisan, P., Jonasch, E., Chow, C. W., Canales, J. R., Tamboli, P., Tannir, N., Wood, C., Monzon, F., Baggerly, K., Varella-Garcia, M., Czerniak, B., Wistuba, I., Mills, G. & 3 others, Shaw, K., Chen, K. & Sircar, K., Nov 1 2017, In: Clinical Cancer Research. 23, 21, p. 6686-6696 11 p.

    Research output: Contribution to journalArticlepeer-review

    48 Scopus citations
  • Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer

    Mitra, S., Montgomery, J. E., Kolar, M. J., Li, G., Jeong, K. J., Peng, B., Verdine, G. L., Mills, G. B. & Moellering, R. E., Dec 1 2017, In: Nature communications. 8, 1, 660.

    Research output: Contribution to journalArticlepeer-review

    33 Scopus citations
  • Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers

    Wang, Y., Xu, X., Yu, S., Jeong, K. J., Zhou, Z., Han, L., Tsang, Y. H., Li, J., Chen, H., Mangala, L. S., Yuan, Y., Eterovic, A. K., Lu, Y., Sood, A. K., Scott, K. L., Mills, G. B. & Liang, H., Jul 2017, In: Genome Research. 27, 7, p. 1112-1125 14 p.

    Research output: Contribution to journalArticlepeer-review

    94 Scopus citations
  • Systems analysis of apoptotic priming in ovarian cancer identifies vulnerabilities and predictors of drug response

    Zervantonakis, I. K., Iavarone, C., Chen, H. Y., Selfors, L. M., Palakurthi, S., Liu, J. F., Drapkin, R., Matulonis, U., Leverson, J. D., Sampath, D., Mills, G. B. & Brugge, J. S., Dec 1 2017, In: Nature communications. 8, 1, 365.

    Research output: Contribution to journalArticlepeer-review

    34 Scopus citations