Gordon Mills

Professor

  • Source: Scopus
  • Calculated based on no. of publications stored in Pure and citations from Scopus
1976 …2021

Research activity per year

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Search results

  • 2018

    β-catenin/TCF activity regulates IGF-1R tyrosine kinase inhibitor sensitivity in colon cancer

    Lee, H., Kim, N., Yoo, Y. J., Kim, H., Jeong, E., Choi, S. G., Moon, S. U., Oh, S. H., Mills, G. B., Yoon, S. & Kim, W. Y., Oct 4 2018, In: Oncogene. 37, 40, p. 5466-5475 10 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • 2017

    A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma

    Krepler, C., Sproesser, K., Brafford, P., Beqiri, M., Garman, B., Xiao, M., Shannan, B., Watters, A., Perego, M., Zhang, G., Vultur, A., Yin, X., Liu, Q., Anastopoulos, I. N., Wubbenhorst, B., Wilson, M. A., Xu, W., Karakousis, G., Feldman, M., Xu, X. & 34 others, Amaravadi, R., Gangadhar, T. C., Elder, D. E., Haydu, L. E., Wargo, J. A., Davies, M. A., Lu, Y., Mills, G. B., Frederick, D. T., Barzily-Rokni, M., Flaherty, K. T., Hoon, D. S., Guarino, M., Bennett, J. J., Ryan, R. W., Petrelli, N. J., Shields, C. L., Terai, M., Sato, T., Aplin, A. E., Roesch, A., Darr, D., Angus, S., Kumar, R., Halilovic, E., Caponigro, G., Jeay, S., Wuerthner, J., Walter, A., Ocker, M., Boxer, M. B., Schuchter, L., Nathanson, K. L. & Herlyn, M., Nov 14 2017, In: Cell Reports. 21, 7, p. 1953-1967 15 p.

    Research output: Contribution to journalArticlepeer-review

    58 Scopus citations
  • Active disclosure of secondary germline findings to deceased research participants' personal representatives: Process and outcomes

    Daniels, M., Wathoo, C., Brusco, L., Lu, K. H., Shaw, K., Dumbrava, E. E. I., Arun, B., Strong, L., Litton, J. K., Eterovic, K., Aytac, U., Mendelsohn, J., Mills, G. B., Chen, K. & Meric-Bernstam, F., 2017, In: JCO Precision Oncology. 2017, 1, p. 1-5 5 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory

    Arango, N. P., Brusco, L., Shaw, K. R. M., Chen, K., Eterovic, A. K., Holla, V., Johnson, A., Litzenburger, B., Khotskaya, Y. B., Sanchez, N., Bailey, A., Zheng, X., Horombe, C., Kopetz, S., Farhangfar, C. J., Routbort, M., Broaddus, R., Bernstam, E. V., Mendelsohn, J., Mills, G. B. & 1 others, Meric-Bernstam, F., 2017, In: Oncotarget. 8, 26, p. 41806-41814 9 p.

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations
  • A murine preclinical syngeneic transplantation model for breast cancer precision medicine

    Federico, L., Chong, Z., Zhang, D., McGrail, D. J., Zhao, W., Jeong, K. J., Vellano, C. P., Ju, Z., Gagea, M., Liu, S., Mitra, S., Dennison, J. B., Lorenzi, P. L., Cardnell, R., Diao, L., Wang, J., Lu, Y., Byers, L. A., Perou, C. M., Lin, S. Y. & 1 others, Mills, G. B., Apr 2017, In: Science Advances. 3, 4, e1600957.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations

    Zhang, Y., Kwok-Shing Ng, P., Kucherlapati, M., Chen, F., Liu, Y., Tsang, Y. H., de Velasco, G., Jeong, K. J., Akbani, R., Hadjipanayis, A., Pantazi, A., Bristow, C. A., Lee, E., Mahadeshwar, H. S., Tang, J., Zhang, J., Yang, L., Seth, S., Lee, S., Ren, X. & 22 others, Song, X., Sun, H., Seidman, J., Luquette, L. J., Xi, R., Chin, L., Protopopov, A., Westbrook, T. F., Shelley, C. S., Choueiri, T. K., Ittmann, M., Van Waes, C., Weinstein, J. N., Liang, H., Henske, E. P., Godwin, A. K., Park, P. J., Kucherlapati, R., Scott, K. L., Mills, G. B., Kwiatkowski, D. J. & Creighton, C. J., Jun 12 2017, In: Cancer Cell. 31, 6, p. 820-832.e3

    Research output: Contribution to journalArticlepeer-review

    178 Scopus citations
  • A population of heterogeneous breast cancer patient-derived xenografts demonstrate broad activity of PARP inhibitor in BRCA1/2 wild-type tumors

    Evans, K. W., Yuca, E., Akcakanat, A., Scott, S. M., Arango, N. P., Zheng, X., Chen, K., Tapia, C., Tarco, E., Eterovic, A. K., Black, D. M., Litton, J. K., Yap, T. A., Tripathy, D., Mills, G. B. & Meric-Bernstam, F., Nov 1 2017, In: Clinical Cancer Research. 23, 21, p. 6468-6477 10 p.

    Research output: Contribution to journalArticlepeer-review

    24 Scopus citations
  • ATG5 mediates a positive feedback loop between wnt signaling and autophagy in melanoma

    Ndoye, A., Budina-Kolomets, A., Kugel, C. H., Webster, M. R., Kaur, A., Behera, R., Rebecca, V. W., Li, L., Brafford, P. A., Liu, Q., Gopal, Y. N. V., Davies, M. A., Mills, G. B., Xu, X., Wu, H., Herlyn, M., Nicastri, M. C., Winkle, J. D., Soengas, M. S., Amaravadi, R. K. & 2 others, Murphy, M. E. & Weeraratna, A. T., Nov 1 2017, In: Cancer Research. 77, 21, p. 5873-5885 13 p.

    Research output: Contribution to journalArticlepeer-review

    16 Scopus citations
  • A unified approach to targeting the lysosome’s degradative and growth signaling roles

    Rebecca, V. W., Nicastri, M. C., McLaughlin, N., Fennelly, C., McAfee, Q., Ronghe, A., Nofal, M., Lim, C. Y., Witze, E., Chude, C. I., Zhang, G., Alicea, G. M., Piao, S., Murugan, S., Ojha, R., Levi, S. M., Wei, Z., Barber-Rotenberg, J. S., Murphy, M. E., Mills, G. B. & 12 others, Lu, Y., Rabinowitz, J., Marmorstein, R., Liu, Q., Liu, S., Xu, X., Herlyn, M., Zoncu, R., Brady, D. C., Speicher, D. W., Winkler, J. D. & Amaravadi, R. K., Nov 2017, In: Cancer discovery. 7, 11, p. 1266-1283 18 p.

    Research output: Contribution to journalArticlepeer-review

    77 Scopus citations
  • Characteristics of percutaneous core biopsies adequate for next generation genomic sequencing

    Sabir, S. H., Krishnamurthy, S., Gupta, S., Mills, G. B., Wei, W., Cortes, A. C., Mills Shaw, K. R., Luthra, R. & Wallace, M. J., Dec 2017, In: PloS one. 12, 12, e0189651.

    Research output: Contribution to journalArticlepeer-review

    10 Scopus citations
  • Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

    Li, J., Zhao, W., Akbani, R., Liu, W., Ju, Z., Ling, S., Vellano, C. P., Roebuck, P., Yu, Q., Eterovic, A. K., Byers, L. A., Davies, M. A., Deng, W., Gopal, Y. N. V., Chen, G., von Euw, E. M., Slamon, D., Conklin, D., Heymach, J. V., Gazdar, A. F. & 5 others, Minna, J. D., Myers, J. N., Lu, Y., Mills, G. B. & Liang, H., Feb 13 2017, In: Cancer Cell. 31, 2, p. 225-239 15 p.

    Research output: Contribution to journalArticlepeer-review

    103 Scopus citations
  • Chk1 inhibition potentiates the therapeutic efficacy of PARP inhibitor BMN673 in gastric cancer

    Yin, Y., Shen, Q., Zhang, P., Tao, R., Chang, W., Li, R., Xie, G., Liu, W., Zhang, L., Kapoor, P., Song, S., Ajani, J., Mills, G. B., Chen, J., Tao, K. & Peng, G., 2017, In: American Journal of Cancer Research. 7, 3, p. 473-483 11 p.

    Research output: Contribution to journalArticlepeer-review

    25 Scopus citations
  • Clinical use of precision oncology decision support

    Johnson, A., Khotskaya, Y. B., Brusco, L., Zeng, J., Holla, V., Bailey, A. M., Litzenburger, B. C., S.Sánchez, N., Shufean, M. A., Piha-Paul, S., Subbiah, V., Hong, D., Routbort, M., Broaddus, R., Mills Shaw, K. R., Mills, G. B., Mendelsohn, J. & Meric-Bernstam, F., 2017, In: JCO Precision Oncology. 2017, 1, p. 1-12 12 p.

    Research output: Contribution to journalArticlepeer-review

    15 Scopus citations
  • Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas

    Huo, D., Hu, H., Rhie, S. K., Gamazon, E. R., Cherniack, A. D., Liu, J., Yoshimatsu, T. F., Pitt, J. J., Hoadley, K. A., Troester, M., Ru, Y., Lichtenberg, T., Sturtz, L. A., Shelley, C. S., Benz, C. C., Mills, G. B., Laird, P. W., Shriver, C. D., Perou, C. M. & Olopade, O. I., Dec 1 2017, In: JAMA Oncology. 3, 12, p. 1654-1662 9 p.

    Research output: Contribution to journalArticlepeer-review

    101 Scopus citations
  • Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

    The Cancer Genome Atlas Research Network, Nov 2 2017, In: Cell. 171, 4, p. 950-965.e28

    Research output: Contribution to journalArticlepeer-review

    265 Scopus citations
  • Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

    The Cancer Genome Atlas Research Network, Jun 15 2017, In: Cell. 169, 7, p. 1327-1341.e23

    Research output: Contribution to journalArticlepeer-review

    652 Scopus citations
  • Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

    Robertson, A. G., Kim, J., Al-Ahmadie, H., Bellmunt, J., Guo, G., Cherniack, A. D., Hinoue, T., Laird, P. W., Hoadley, K. A., Akbani, R., Castro, M. A. A., Gibb, E. A., Kanchi, R. S., Gordenin, D. A., Shukla, S. A., Sanchez-Vega, F., Hansel, D. E., Czerniak, B. A., Reuter, V. E., Su, X. & 153 others, de Sa Carvalho, B., Chagas, V. S., Mungall, K. L., Sadeghi, S., Pedamallu, C. S., Lu, Y., Klimczak, L. J., Zhang, J., Choo, C., Ojesina, A. I., Bullman, S., Leraas, K. M., Lichtenberg, T. M., Wu, C. J., Schultz, N., Getz, G., Meyerson, M., Mills, G. B., McConkey, D. J., Albert, M., Alexopoulou, I., Ally, A., Antic, T., Aron, M., Balasundaram, M., Bartlett, J., Baylin, S. B., Beaver, A., Birol, I., Boice, L., Bootwalla, M. S., Bowen, J., Bowlby, R., Brooks, D., Broom, B. M., Bshara, W., Burks, E., Cárcano, F. M., Carlsen, R., Carvalho, A. L., Castle, E. P., Castro, P., Catto, J. W., Chesla, D. W., Chuah, E., Chudamani, S., Cortessis, V. K., Cottingham, S. L., Crain, D., Curley, E., Daneshmand, S., Demchok, J. A., Dhalla, N., Djaladat, H., Eckman, J., Egea, S. C., Engel, J., Felau, I., Ferguson, M. L., Gardner, J., Gastier-Foster, J. M., Gerken, M., Gomez-Fernandez, C. R., Harr, J., Hartmann, A., Herbert, L. M., Ho, T. H., Holt, R. A., Hutter, C. M., Jones, S. J. M., Jorda, M., Kahnoski, R. J., Kasaian, K., Kwiatkowski, D. J., Lai, P. H., Lane, B. R., Lerner, S. P., Liu, J., Lolla, L., Lotan, Y., Lucchesi, F. R., Ma, Y., Machado, R. D., Maglinte, D. T., Mallery, D., Marra, M. A., Martin, S. E., Mayo, M., Meraney, A., Moinzadeh, A., Moore, R. A., Mora Pinero, E. M., Morris, S., Morrison, C., Mungall, A. J., Myers, J. B., Naresh, R., O'Donnell, P. H., Parekh, D. J., Parfitt, J., Paulauskis, J. D., Sekhar Pedamallu, C., Penny, R. J., Pihl, T., Porten, S., Quintero-Aguilo, M. E., Ramirez, N. C., Rathmell, W. K., Rieger-Christ, K., Saller, C., Salner, A., Sandusky, G., Scapulatempo-Neto, C., Schein, J. E., Schuckman, A. K., Shelton, C., Shelton, T., Simko, J., Singh, P., Sipahimalani, P., Smith, N. D., Sofia, H. J., Sorcini, A., Stanton, M. L., Steinberg, G. D., Stoehr, R., Su, X., Sullivan, T., Sun, Q., Tam, A., Tarnuzzer, R., Tarvin, K., Taubert, H., Thiessen, N., Thorne, L., Tse, K., Tucker, K., Van Den Berg, D. J., van Kessel, K. E., Wach, S., Wan, Y., Wang, Z., Weinstein, J. N., Weisenberger, D. J., Wise, L., Wong, T., Wu, Y., Yang, L., Zach, L. A., Zenklusen, J. C., Zhang, J. J., Zmuda, E. & Zwarthoff, E. C., Oct 19 2017, In: Cell. 171, 3, p. 540-556.e25

    Research output: Contribution to journalArticlepeer-review

    716 Scopus citations
  • Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma

    Fishbein, L., Leshchiner, I., Walter, V., Danilova, L., Robertson, A. G., Johnson, A. R., Lichtenberg, T. M., Murray, B. A., Ghayee, H. K., Else, T., Ling, S., Jefferys, S. R., de Cubas, A. A., Wenz, B., Korpershoek, E., Amelio, A. L., Makowski, L., Rathmell, W. K., Gimenez-Roqueplo, A. P., Giordano, T. J. & 187 others, Asa, S. L., Tischler, A. S., Akbani, R., Ally, A., Amar, L., Arachchi, H., Auchus, R. J., Auman, J. T., Baertsch, R., Balasundaram, M., Balu, S., Bartsch, D. K., Baudin, E., Bauer, T., Beaver, A., Benz, C., Beroukhim, R., Beuschlein, F., Bodenheimer, T., Boice, L., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Carter, S., Cassol, C. A., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cope, L., Crain, D., Curley, E., de Krijger, R. R., Demchok, J. A., Deutschbein, T., Dhalla, N., Dimmock, D., Dinjens, W. N. M., Eng, C., Eschbacher, J., Fassnacht, M., Felau, I., Feldman, M., Ferguson, M. L., Fiddes, I., Frazer, S., Gabriel, S. B., Gardner, J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Geurts, J., Goldman, M., Graim, K., Gupta, M., Haan, D., Hahner, S., Hantel, C., Haussler, D., Hayes, D. N., Heiman, D. I., Hoadley, K. A., Holt, R. A., Hoyle, A. P., Huang, M., Hunt, B., Hutter, C. M., Jones, S. J. M., Jones, C. D., Kasaian, K., Kebebew, E., Kim, J., Kimes, P., Knijnenburg, T., Lander, E., Lawrence, M. S., Lechan, R., Lee, D., Leraas, K. M., Lerario, A., Lin, P., Liu, J., LiVolsi, V. A., Lolla, L., Lotan, Y., Lu, Y., Ma, Y., Maison, N., Mallery, D., Mannelli, M., Marquard, J., Marra, M. A., Matthew, T., Mayo, M., Méatchi, T., Meng, S., Merino, M. J., Mete, O., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Morozova, O., Morris, S., Mose, L. E., Mungall, A. J., Naresh, R., Nathanson, K. L., Newton, Y., Ng, S., Ni, Y., Noble, M. S., Nwariaku, F., Pacak, K., Parker, J. S., Paul, E., Penny, R., Perou, C. M., Perou, A. H., Pihl, T., Powers, J., Rabaglia, J., Radenbaugh, A., Ramirez, N. C., Rao, A., Riester, A., Roach, J., Sadeghi, S., Saksena, G., Salama, S., Saller, C., Sandusky, G., Sbiera, S., Schein, J. E., Schumacher, S. E., Shelton, C., Shelton, T., Sheth, M., Shi, Y., Shih, J., Shmulevich, I., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Sokolov, A., Soloway, M. G., Sougnez, C., Stuart, J., Sun, C., Swatloski, T., Tam, A., Tan, D., Tarnuzzer, R., Tarvin, K., Thiessen, N., Thorne, L. B., Timmers, H. J., Tse, K., Uzunangelov, V., van Berkel, A., Veluvolu, U., Vicha, A., Voet, D., Waldmann, J., Wan, Y., Wang, Z., Wang, T. S., Weaver, J., Weinstein, J. N., Weismann, D., Wilkerson, M. D., Wise, L., Wong, T., Wong, C., Wu, Y., Yang, L., Zelinka, T., Zenklusen, J. C., Zhang, J. J., Zhang, W., Zhu, J., Zinzindohoué, F. & Zmuda, E., Feb 13 2017, In: Cancer Cell. 31, 2, p. 181-193 13 p.

    Research output: Contribution to journalArticlepeer-review

    245 Scopus citations
  • Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

    Hill, S. M., Nesser, N. K., Johnson-Camacho, K., Jeffress, M., Johnson, A., Boniface, C., Spencer, S. E. F., Lu, Y., Heiser, L. M., Lawrence, Y., Pande, N. T., Korkola, J. E., Gray, J. W., Mills, G. B., Mukherjee, S. & Spellman, P. T., Jan 25 2017, In: Cell Systems. 4, 1, p. 73-83.e10

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations
  • Correction: Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer (PLoS ONE (2015) 10:7 (e0133219) DOI: 10.1371/journal.pone.0133219)

    Korkola, J. E., Collisson, E. A., Heiser, L. M., Oates, C., Bayani, N., Itani, S., Esch, A., Thompson, W., Griffith, O. L., Wang, N. J., Kuo, W. L., Cooper, B., Billig, J., Ziyad, S., Hung, J. L., Jakkula, L., Feiler, H., Lu, Y., Mills, G. B., Spellman, P. T. & 3 others, Tomlin, C., Mukherjee, S. & Gray, J. W., Oct 2017, In: PloS one. 12, 10, e0186551.

    Research output: Contribution to journalComment/debatepeer-review

  • CTNNB1 (beta-catenin) mutation identifies low grade, early stage endometrial cancer patients at increased risk of recurrence

    Kurnit, K. C., Kim, G. N., Fellman, B. M., Urbauer, D. L., Mills, G. B., Zhang, W. & Broaddus, R. R., Jul 1 2017, In: Modern Pathology. 30, 7, p. 1032-1041 10 p.

    Research output: Contribution to journalArticlepeer-review

    76 Scopus citations
  • Development and validation of an ultradeep next-generation sequencing assay for testing of plasma cell-free DNA from patients with advanced cancer

    Janku, F., Zhang, S., Waters, J., Liu, L., Huang, H. J., Subbiah, V., Hong, D. S., Karp, D. D., Fu, S., Cai, X., Ramzanali, N. M., Madwani, K., Cabrilo, G., Andrews, D. L., Zhao, Y., Javle, M., Kopetz, E. S., Luthra, R., Kim, H. J., Gnerre, S. & 11 others, Satya, R. V., Chuang, H. Y., Kruglyak, K. M., Toung, J., Zhao, C., Shen, R., Heymach, J. V., Meric-Bernstam, F., Mills, G. B., Fan, J. B. & Salathia, N. S., Sep 15 2017, In: Clinical Cancer Research. 23, 18, p. 5648-5656 9 p.

    Research output: Contribution to journalArticlepeer-review

    28 Scopus citations
  • Engineering and functional characterization of fusion genes identifies novel oncogenic drivers of cancer

    Lu, H., Villafane, N., Dogruluk, T., Grzeskowiak, C. L., Kong, K., Tsang, Y. H., Zagorodna, O., Pantazi, A., Yang, L., Neill, N. J., Kim, Y. W., Creighton, C. J., Verhaak, R. G., Mills, G. B., Park, P. J., Kucherlapati, R. & Scott, K. L., Jul 1 2017, In: Cancer Research. 77, 13, p. 3502-3512 11 p.

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations
  • Epigenetic regulation of KPC1 ubiquitin ligase affects the NF-κB pathway in melanoma

    Iida, Y., Ciechanover, A., Marzese, D. M., Hata, K., Bustos, M., Ono, S., Wang, J., Salomon, M. P., Tran, K., Lam, S., Hsu, S., Nelson, N., Kravtsova-Ivantsiv, Y., Mills, G. B., Davies, M. A. & Hoon, D. S. B., Aug 15 2017, In: Clinical Cancer Research. 23, 16, p. 4831-4842 12 p.

    Research output: Contribution to journalArticlepeer-review

    17 Scopus citations
  • Erratum: Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles (Cell Reports (2017) 18(11) (2780–2794) (S2211124717302140) (10.1016/j.celrep.2017.02.033))

    The Cancer Genome Atlas Network, Jun 27 2017, In: Cell Reports. 19, 13, p. 2878-2880 3 p.

    Research output: Contribution to journalComment/debatepeer-review

    61 Scopus citations
  • Establishment of patient-derived tumor xenograft models of epithelial ovarian cancer for preclinical evaluation of novel therapeutics

    Liu, J. F., Palakurthi, S., Zeng, Q., Zhou, S., Ivanova, E., Huang, W., Zervantonakis, I. K., Selfors, L. M., Shen, Y., Pritchard, C. C., Zheng, M., Adleff, V., Papp, E., Piao, H., Novak, M., Fotheringham, S., Wulf, G. M., English, J., Kirschmeier, P. T., Velculescu, V. E. & 6 others, Paweletz, C., Mills, G. B., Livingston, D. M., Brugge, J. S., Matulonis, U. A. & Drapkin, R., Mar 1 2017, In: Clinical Cancer Research. 23, 5, p. 1263-1273 11 p.

    Research output: Contribution to journalArticlepeer-review

    46 Scopus citations
  • Explore, visualize, and analyze functional cancer proteomic data using the cancer proteome atlas

    Li, J., Akbani, R., Zhao, W., Lu, Y., Weinstein, J. N., Mills, G. B. & Liang, H., Nov 1 2017, In: Cancer Research. 77, 21, p. e51-e54

    Research output: Contribution to journalArticlepeer-review

    35 Scopus citations
  • Functional proteomic characterization of cancer cell lines

    Zhao, W., Li, J. & Mills, G., Jan 1 2017, In: Oncoscience. 4, 5-6, p. 41-42 2 p.

    Research output: Contribution to journalEditorialpeer-review

    1 Scopus citations
  • Functional variomics and network perturbation: Connecting genotype to phenotype in cancer

    Yi, S., Lin, S., Li, Y., Zhao, W., Mills, G. B. & Sahni, N., Jul 1 2017, In: Nature Reviews Genetics. 18, 7, p. 395-410 16 p.

    Research output: Contribution to journalReview articlepeer-review

    45 Scopus citations
  • Genomic analysis of exceptional responder to regorafenib in treatment-refractory metastatic rectal cancer: A case report and review of the literature

    Korphaisarn, K., Loree, J. M., Nguyen, V., Coulson, R., Holla, V., Litzenburger, B. C., Chen, K., Mills, G. B., Maru, D. M., Meric-Bernstan, F., Shaw, K. R. M. & Kopetz, S., 2017, In: Oncotarget. 8, 34, p. 57882-57888 7 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • Identifying abundant immunotherapy and other targets in solid tumors integrating RNA-seq and mass spectrometry proteomics data sets

    Zhao, W., Fitzgibbon, M., Bergan, L., Clegg, N., Crispin, D., Mills, G. B. & Mcintosh, M., 2017, In: Cancer Journal (United States). 23, 2, p. 108-114 7 p.

    Research output: Contribution to journalReview articlepeer-review

  • Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm

    McGrail, D. J., Lin, C. C. J., Garnett, J., Liu, Q., Mo, W., Dai, H., Lu, Y., Yu, Q., Ju, Z., Yin, J., Vellano, C. P., Hennessy, B., Mills, G. B. & Lin, S. Y., Dec 1 2017, In: npj Systems Biology and Applications. 3, 1, 8.

    Research output: Contribution to journalArticlepeer-review

    25 Scopus citations
  • Integrated genomic and molecular characterization of cervical cancer

    The Cancer Genome Atlas Research Network, Mar 16 2017, In: Nature. 543, 7645, p. 378-384 7 p.

    Research output: Contribution to journalArticlepeer-review

    531 Scopus citations
  • Integrated genomic characterization of oesophageal carcinoma

    The Cancer Genome Atlas Research Network, Jan 12 2017, In: Nature. 541, 7636, p. 169-174 6 p.

    Research output: Contribution to journalArticlepeer-review

    656 Scopus citations
  • Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

    Raphael, B. J., Hruban, R. H., Aguirre, A. J., Moffitt, R. A., Yeh, J. J., Stewart, C., Robertson, A. G., Cherniack, A. D., Gupta, M., Getz, G., Gabriel, S. B., Meyerson, M., Cibulskis, C., Fei, S. S., Hinoue, T., Shen, H., Laird, P. W., Ling, S., Lu, Y., Mills, G. B. & 251 others, Akbani, R., Loher, P., Londin, E. R., Rigoutsos, I., Telonis, A. G., Gibb, E. A., Goldenberg, A., Mezlini, A. M., Hoadley, K. A., Collisson, E., Lander, E., Murray, B. A., Hess, J., Rosenberg, M., Bergelson, L., Zhang, H., Cho, J., Tiao, G., Kim, J., Livitz, D., Leshchiner, I., Reardon, B., Van Allen, E., Kamburov, A., Beroukhim, R., Saksena, G., Schumacher, S. E., Noble, M. S., Heiman, D. I., Gehlenborg, N., Kim, J., Lawrence, M. S., Adsay, V., Petersen, G., Klimstra, D., Bardeesy, N., Leiserson, M. D. M., Bowlby, R., Kasaian, K., Birol, I., Mungall, K. L., Sadeghi, S., Weinstein, J. N., Spellman, P. T., Liu, Y., Amundadottir, L. T., Tepper, J., Singhi, A. D., Dhir, R., Paul, D., Smyrk, T., Zhang, L., Kim, P., Bowen, J., Frick, J., Gastier-Foster, J. M., Gerken, M., Lau, K., Leraas, K. M., Lichtenberg, T. M., Ramirez, N. C., Renkel, J., Sherman, M., Wise, L., Yena, P., Zmuda, E., Shih, J., Ally, A., Balasundaram, M., Carlsen, R., Chu, A., Chuah, E., Clarke, A., Dhalla, N., Holt, R. A., Jones, S. J. M., Lee, D., Ma, Y., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Tse, K., Wong, T., Brooks, D., Auman, J. T., Balu, S., Bodenheimer, T., Hayes, D. N., Hoyle, A. P., Jefferys, S. R., Jones, C. D., Meng, S., Mieczkowski, P. A., Mose, L. E., Perou, C. M., Perou, A. H., Roach, J., Shi, Y., Simons, J. V., Skelly, T., Soloway, M. G., Tan, D., Veluvolu, U., Parker, J. S., Wilkerson, M. D., Korkut, A., Senbabaoglu, Y., Burch, P., McWilliams, R., Chaffee, K., Oberg, A., Zhang, W., Gingras, M. C., Wheeler, D. A., Xi, L., Albert, M., Bartlett, J., Sekhon, H., Stephen, Y., Howard, Z., Judy, M., Breggia, A., Shroff, R. T., Chudamani, S., Liu, J., Lolla, L., Naresh, R., Pihl, T., Sun, Q., Wan, Y., Wu, Y., Jennifer, S., Roggin, K., Becker, K. F., Behera, M., Bennett, J., Boice, L., Burks, E., Carlotti Junior, C. G., Chabot, J., Pretti da Cunha Tirapelli, D., Sebastião dos Santos, J., Dubina, M., Eschbacher, J., Huang, M., Huelsenbeck-Dill, L., Jenkins, R., Karpov, A., Kemp, R., Lyadov, V., Maithel, S., Manikhas, G., Montgomery, E., Noushmehr, H., Osunkoya, A., Owonikoko, T., Paklina, O., Potapova, O., Ramalingam, S., Rathmell, W. K., Rieger-Christ, K., Saller, C., Setdikova, G., Shabunin, A., Sica, G., Su, T., Sullivan, T., Swanson, P., Tarvin, K., Tavobilov, M., Thorne, L. B., Urbanski, S., Voronina, O., Wang, T., Crain, D., Curley, E., Gardner, J., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, C., Shelton, T., Janssen, K. P., Bathe, O., Bahary, N., Slotta-Huspenina, J., Johns, A., Hibshoosh, H., Hwang, R. F., Sepulveda, A., Radenbaugh, A., Baylin, S. B., Berrios, M., Bootwalla, M. S., Holbrook, A., Lai, P. H., Maglinte, D. T., Mahurkar, S., Triche, T. J., Van Den Berg, D. J., Weisenberger, D. J., Chin, L., Kucherlapati, R., Kucherlapati, M., Pantazi, A., Park, P., Saksena, G., Voet, D., Lin, P., Frazer, S., Defreitas, T., Meier, S., Chin, L., Kwon, S. Y., Kim, Y. H., Park, S. J., Han, S. S., Kim, S. H., Kim, H., Furth, E., Tempero, M., Sander, C., Biankin, A., Chang, D., Bailey, P., Gill, A., Kench, J., Grimmond, S., Johns, A., Cancer Genome Initiative (APGI, A. P., Postier, R., Zuna, R., Sicotte, H., Demchok, J. A., Ferguson, M. L., Hutter, C. M., Mills Shaw, K. R., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zhang, J. J., Felau, I. & Zenklusen, J. C., Aug 14 2017, In: Cancer Cell. 32, 2, p. 185-203.e13

    Research output: Contribution to journalArticlepeer-review

    526 Scopus citations
  • Integrated Molecular Characterization of Uterine Carcinosarcoma

    Cherniack, A. D., Shen, H., Walter, V., Stewart, C., Murray, B. A., Bowlby, R., Hu, X., Ling, S., Soslow, R. A., Broaddus, R. R., Zuna, R. E., Robertson, G., Laird, P. W., Kucherlapati, R., Mills, G. B., Akbani, R., Ally, A., Auman, J. T., Balasundaram, M., Balu, S. & 130 others, Baylin, S. B., Beroukhim, R., Bodenheimer, T., Bogomolniy, F., Boice, L., Bootwalla, M. S., Bowen, J., Broaddus, R., Brooks, D., Carlsen, R., Cho, J., Chuah, E., Chudamani, S., Cibulskis, K., Cline, M., Dao, F., David, M., Demchok, J. A., Dhalla, N., Dowdy, S., Felau, I., Ferguson, M. L., Frazer, S., Frick, J., Gabriel, S., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Gupta, M., Haussler, D., Hayes, D. N., Heiman, D. I., Hess, J., Hoadley, K. A., Hoffmann, R., Holt, R. A., Hoyle, A. P., Huang, M., Hutter, C. M., Jefferys, S. R., Jones, S. J. M., Jones, C. D., Kanchi, R. S., Kandoth, C., Kasaian, K., Kerr, S., Kim, J., Lai, P. H., Lander, E., Lawrence, M. S., Lee, D., Leraas, K. M., Leshchiner, I., Levine, D. A., Lichtenberg, T. M., Lin, P., Liu, J., Liu, W., Liu, Y., Lolla, L., Lu, Y., Ma, Y., Maglinte, D. T., Marra, M. A., Mayo, M., Meng, S., Meyerson, M., Mieczkowski, P. A., Moore, R. A., Mose, L. E., Mungall, A. J., Mungall, K., Naresh, R., Noble, M. S., Olvera, N., Parker, J. S., Perou, C. M., Perou, A. H., Pihl, T., Radenbaugh, A. J., Ramirez, N. C., Rathmell, W. K., Roach, J., Robertson, A. G., Sadeghi, S., Saksena, G., Salvesen, H. B., Schein, J. E., Schumacher, S. E., Sheth, M., Shi, Y., Shih, J., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Soloway, M. G., Sougnez, C., Sun, C., Tam, A., Tan, D., Tarnuzzer, R., Thiessen, N., Thorne, L. B., Tse, K., Tseng, J., Van Den Berg, D. J., Veluvolu, U., Verhaak, R. G. W., Voet, D., von Bismarck, A., Wan, Y., Wang, Z., Wang, C., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Winterhoff, B., Wise, L., Wong, T., Wu, Y., Yang, L., Zenklusen, J. C., Zhang, J. J., Zhang, H., Zhang, W., Zhu, J. C., Zmuda, E. & Zhang, J., Mar 13 2017, In: Cancer Cell. 31, 3, p. 411-423 13 p.

    Research output: Contribution to journalArticlepeer-review

    140 Scopus citations
  • Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

    Robertson, A. G., Shih, J., Yau, C., Gibb, E. A., Oba, J., Mungall, K. L., Hess, J. M., Uzunangelov, V., Walter, V., Danilova, L., Lichtenberg, T. M., Kucherlapati, M., Kimes, P. K., Tang, M., Penson, A., Babur, O., Akbani, R., Bristow, C. A., Hoadley, K. A., Iype, L. & 150 others, Chang, M. T., Abdel-Rahman, M. H., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., Benz, C., Beroukhim, R., Birol, I., Bodenheimer, T., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Cebulla, C. M., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cibulskis, C., Cibulskis, K., Cope, L., Coupland, S. E., Defreitas, T., Demchok, J. A., Desjardins, L., Dhalla, N., Esmaeli, B., Felau, I., Ferguson, M. L., Frazer, S., Gabriel, S. B., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Gershenwald, J. E., Getz, G., Griewank, K. G., Grimm, E. A., Hayes, D. N., Hegde, A. M., Heiman, D. I., Helsel, C., Hobensack, S., Holt, R. A., Hoyle, A. P., Hu, X., Hutter, C. M., Jager, M. J., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Kandoth, C., Kasaian, K., Kim, J., Kucherlapati, R., Lander, E., Lawrence, M. S., Lazar, A. J., Lee, S., Leraas, K. M., Lin, P., Liu, J., Liu, W., Lolla, L., Lu, Y., Ma, Y., Mahadeshwar, H. S., Mariani, O., Marra, M. A., Mayo, M., Meier, S., Meng, S., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Naresh, R., Noble, M. S., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Pihl, T., Pilarski, R., Protopopov, A., Radenbaugh, A., Rai, K., Ramirez, N. C., Ren, X., Reynolds, S. M., Roach, J., Roman-Roman, S., Roszik, J., Sadeghi, S., Saksena, G., Sastre, X., Schadendorf, D., Schein, J. E., Schoenfield, L., Schumacher, S. E., Seidman, J., Seth, S., Sethi, G., Sheth, M., Shi, Y., Shields, C., Shmulevich, I., Simons, J. V., Singh, A. D., Sipahimalani, P., Skelly, T., Sofia, H., Soloway, M. G., Song, X., Stern, M. H., Stuart, J., Sun, Q., Sun, H., Tam, A., Tan, D., Tang, J., Tarnuzzer, R., Taylor, B. S., Thiessen, N., Thorsson, V., Tse, K., Veluvolu, U., Verhaak, R. G. W., Voet, D., Wan, Y., Wang, Z., Weinstein, J. N., Wilkerson, M. D., Williams, M. D., Wise, L., Woodman, S. E., Wong, T., Wu, Y., Yang, L., Yang, L., Zenklusen, J. C., Zhang, J., Zhang, H. & Zmuda, E., Aug 14 2017, In: Cancer Cell. 32, 2, p. 204-220.e15

    Research output: Contribution to journalArticlepeer-review

    267 Scopus citations
  • Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome

    Aure, M. R., Vitelli, V., Jernström, S., Kumar, S., Krohn, M., Due, E. U., Haukaas, T. H., Leivonen, S. K., Vollan, H. K. M., Lüders, T., Rødland, E., Vaske, C. J., Zhao, W., Møller, E. K., Nord, S., Giskeødegård, G. F., Bathen, T. F., Caldas, C., Tramm, T., Alsner, J. & 26 others, Overgaard, J., Geisler, J., Bukholm, I. R. K., Naume, B., Schlichting, E., Sauer, T., Mills, G. B., Kåresen, R., Mælandsmo, G. M., Lingjærde, O. C., Frigessi, A., Kristensen, V. N., Børresen-Dale, A. L., Sahlberg, K. K., Borgen, E., Engebråten, O., Fodstad, Ø., Fritzman, B., Garred, Ø., Geitvik, G. A., Langerød, A., Hofvind, S., Russnes, H. G., Skjerven, H. K., Sørlie, T. & OSBREAC, Mar 29 2017, In: Breast Cancer Research. 19, 1, 44.

    Research output: Contribution to journalArticlepeer-review

    37 Scopus citations
  • Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles

    CONSORTIA, Mar 14 2017, In: Cell Reports. 18, 11, p. 2780-2794 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    158 Scopus citations
  • Loss-of-function screens of druggable targetome against cancer stem-like cells

    Song, M., Lee, H., Nam, M. H., Jeong, E., Kim, S., Hong, Y., Kim, N., Yim, H. Y., Yoo, Y. J., Kim, J. S., Kim, J. S., Cho, Y. Y., Mills, G. B., Kim, W. Y. & Yoon, S., Feb 2017, In: FASEB Journal. 31, 2, p. 625-935 311 p.

    Research output: Contribution to journalArticlepeer-review

    16 Scopus citations
  • Molecular heterogeneity at the network level: High-dimensional testing, clustering and a TCGA case study

    Städler, N., Dondelinger, F., Hill, S. M., Akbani, R., Lu, Y., Mills, G. B. & Mukherjee, S., Sep 15 2017, In: Bioinformatics. 33, 18, p. 2890-2896 7 p.

    Research output: Contribution to journalArticlepeer-review

    9 Scopus citations
  • Multiplatform-based molecular subtypes of non-small-cell lung cancer

    Chen, F., Zhang, Y., Parra, E., Rodriguez, J., Behrens, C., Akbani, R., Lu, Y., Kurie, J. M., Gibbons, D. L., Mills, G. B., Wistuba, I. I. & Creighton, C. J., Mar 1 2017, In: Oncogene. 36, 10, p. 1384-1393 10 p.

    Research output: Contribution to journalArticlepeer-review

    55 Scopus citations
  • Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer

    Kang, M. H., Jeong, K. J., Kim, W. Y., Lee, H. J., Gong, G., Suh, N., Gyrffy, B., Kim, S., Jeong, S. Y., Mills, G. B. & Park, Y. Y., Mar 23 2017, In: Oncogene. 36, 12, p. 1745-1752 8 p.

    Research output: Contribution to journalArticlepeer-review

    31 Scopus citations
  • Neomorphic mutations create therapeutic challenges in cancer

    Takiar, V., Ip, C. K. M., Gao, M., Mills, G. B. & Cheung, L. W. T., Mar 23 2017, In: Oncogene. 36, 12, p. 1607-1618 12 p.

    Research output: Contribution to journalReview articlepeer-review

    14 Scopus citations
  • Next-Generation Sequencing and Result Interpretation in Clinical Oncology: Challenges of Personalized Cancer Therapy

    Khotskaya, Y. B., Mills, G. B. & Mills Shaw, K. R., Jan 14 2017, In: Annual review of medicine. 68, p. 113-125 13 p.

    Research output: Contribution to journalArticlepeer-review

    21 Scopus citations
  • Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo

    Zoeller, J. J., Bronson, R. T., Selfors, L. M., Mills, G. B. & Brugge, J. S., Dec 1 2017, In: npj Breast Cancer. 3, 1, 18.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • Oncogenic RAS Regulates Long Noncoding RNA Orilnc1 in Human Cancer

    Zhang, D., Zhang, G., Hu, X., Wu, L., Feng, Y., He, S., Zhang, Y., Hu, Z., Yang, L., Tian, T., Xu, W., Wei, Z., Lu, Y., Flaherty, K. T., Zhong, X., Mills, G. B., Gimotty, P. A., Xu, X., Herlyn, M. & Zhang, L., Jul 15 2017, In: Cancer Research. 77, 14, p. 3745-3757 13 p.

    Research output: Contribution to journalArticlepeer-review

    13 Scopus citations
  • PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas

    Lu, H., Liu, S., Zhang, G., Wu, B., Zhu, Y., Frederick, D. T., Hu, Y., Zhong, W., Randell, S., Sadek, N., Zhang, W., Chen, G., Cheng, C., Zeng, J., Wu, L. W., Zhang, J., Liu, X., Xu, W., Krepler, C., Sproesser, K. & 21 others, Xiao, M., Miao, B., Liu, J., Song, C. D., Liu, J. Y., Karakousis, G. C., Schuchter, L. M., Lu, Y., Mills, G., Cong, Y., Chernoff, J., Guo, J., Boland, G. M., Sullivan, R. J., Wei, Z., Field, J., Amaravadi, R. K., Flaherty, K. T., Herlyn, M., Xu, X. & Guo, W., Oct 5 2017, In: Nature. 550, 7674, p. 133-136 4 p.

    Research output: Contribution to journalArticlepeer-review

    80 Scopus citations
  • Patient-derived xenograft models of ovarian/gynecologic tumors

    Liang, L., Mercado-Uribe, I., Niu, N., Jiang, Y., Cheng, W., Zhang, J., Mills, G. B., Scott, C., Sood, A. K. & Liu, J., 2017, Patient Derived Tumor Xenograft Models: Promise, Potential and Practice. Elsevier Inc., p. 257-271 15 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • Personalized cancer therapy: A publicly available precision oncology resource

    Kurnit, K. C., Bailey, A. M., Zeng, J., Johnson, A. M., Shufean, M. A., Brusco, L., Litzenburger, B. C., Sanchez, N. S., Khotskaya, Y. B., Holla, V., Simpson, A., Mills, G. B., Mendelsohn, J., Bernstam, E., Shaw, K. & Meric-Bernstam, F., Nov 1 2017, In: Cancer Research. 77, 21, p. e123-e126

    Research output: Contribution to journalArticlepeer-review

    21 Scopus citations