Erik Tucker

Research Assistant Professor

  • 1092 Citations
  • 18 h-Index
20072019
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Factor XI Medicine & Life Sciences
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Primates Medicine & Life Sciences

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Research Output 2007 2019

  • 1092 Citations
  • 18 h-Index
  • 36 Article
  • 1 Chapter
  • 1 Letter

Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial

Lorentz, C. U., Verbout, N. G., Wallisch, M., Hagen, M. W., Shatzel, J. J., Olson, S. R., Puy, C., Hinds, M., McCarty, O., Gailani, D., Gruber, A. & Tucker, E., Apr 1 2019, In : Arteriosclerosis, thrombosis, and vascular biology. 39, 4, p. 799-809 11 p.

Research output: Contribution to journalArticle

Open Access
Factor XI
Antibodies
Thrombosis
Hemostasis
Primates

Inhibition of contact-mediated activation of factor XI protects baboons against S aureus-induced organ damage and death

Silasi, R., Keshari, R. S., Lupu, C., Van Rensburg, W. J., Chaaban, H., Regmi, G., Shamanaev, A., Shatzel, J. J., Puy, C., Lorentz, C. U., Tucker, E., Gailani, D., Gruber, A., McCarty, O. & Lupu, F., Feb 26 2019, In : Blood advances. 3, 4, p. 658-669 12 p.

Research output: Contribution to journalArticle

Open Access
Factor XI
Contact Inhibition
Papio
Sepsis
Disseminated Intravascular Coagulation
1 Citation (Scopus)

Factor XI contributes to myocardial ischemia-reperfusion injury in mice

Lorentz, C. U., Verbout, N. G., Cao, Z., Liu, L., Hinds, M., McCarty, O., Ivanov, I., Tucker, E., Gailani, D. & Gruber, A., Jan 23 2018, In : Blood advances. 2, 2, p. 85-88 4 p.

Research output: Contribution to journalArticle

Factor XIIa
Factor XI
Protein Interaction Domains and Motifs
Myocardial Reperfusion Injury
Reperfusion Injury
1 Citation (Scopus)

Factor XII Activation Promotes Platelet Consumption in the Presence of Bacterial-Type Long-Chain Polyphosphate In Vitro and In Vivo

Zilberman-Rudenko, J., Reitsma, S. E., Puy, C., Rigg, R. A., Smith, S. A., Tucker, E., Silasi, R., Merkulova, A., McCrae, K. R., Maas, C., Urbanus, R. T., Gailani, D., Morrissey, J. H., Gruber, A., Lupu, F., Schmaier, A. H. & McCarty, O., Aug 1 2018, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 8, p. 1748-1760 13 p.

Research output: Contribution to journalArticle

Factor XII
Polyphosphates
Platelet Activation
Blood Platelets
Sepsis

Removal of the C-terminal domains of ADAMTS13 by activated coagulation factor XI induces platelet adhesion on endothelial cells under flow conditions

Garland, K. S., Reitsma, S. E., Shirai, T., Zilberman-Rudenko, J., Tucker, E., Gailani, D., Gruber, A., McCarty, O. & Puy, C., Jan 1 2017, In : Frontiers in Medicine. 4, DEC, 232.

Research output: Contribution to journalArticle

Open Access
Factor XIa
Factor XI
von Willebrand Factor
Blood Platelets
Endothelial Cells