Eric Simpson

Professor

  • 7646 Citations
  • 44 h-Index
20012019
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Research Output 2001 2019

21 Citations (Scopus)
Atopic Dermatitis
Complementary Therapies
Cross-Sectional Studies
Skin Diseases
Frustration
24 Citations (Scopus)

Activation of HIV in human skin by ultraviolet B radiation and its inhibition by NFκB blocking agents

Breuer-McHam, J., Simpson, E., Dougherty, I., Bonkobara, M., Ariizumi, K., Lewis, D. E., Dawson, D. B., Duvic, M. & Cruz, P. D., Dec 1 2001, In : Photochemistry and Photobiology. 74, 6, p. 805-810 6 p.

Research output: Contribution to journalArticle

human immunodeficiency virus
NF-kappa B
Skin
Chemical activation
HIV
11 Citations (Scopus)
Deodorants
Lichens
Allergic Contact Dermatitis
Hypersensitivity
Acids

Alopecia areata in 2 patients treated with dupilumab: New onset and worsening

Chung, J., Slaught, C. L. & Simpson, E., Aug 1 2019, In : JAAD Case Reports. 5, 8, p. 643-645 3 p.

Research output: Contribution to journalArticle

Open Access
Alopecia Areata
Atopic Dermatitis
Alopecia Areata 2
SAR231893
15 Citations (Scopus)

Altered composition of epidermal lipids correlates with Staphylococcus aureus colonization status in atopic dermatitis

Li, S., Villarreal, M., Stewart, S., Choi, J., Ganguli-Indra, G., Babineau, D. C., Philpot, C., David, G., Yoshida, T., Boguniewicz, M., Hanifin, J., Beck, L. A., Leung, D. Y., Simpson, E. & Indra, A. K., 2017, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalArticle

33 Citations (Scopus)

A new body moisturizer increases skin hydration and improves atopic dermatitis symptoms among children and adults

Simpson, E. & Dutronc, Y., Jul 2011, In : Journal of Drugs in Dermatology. 10, 7, p. 744-749 6 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Skin
cetyl alcohol, propylene glycol, sodium lauryl sulfate non-lipid cleansing lotion
16 Citations (Scopus)

A Phase 2 Randomized Trial of Apremilast in Patients with Atopic Dermatitis

Simpson, E., Imafuku, S., Poulin, Y., Ungar, B., Zhou, L., Malik, K., Wen, H. C., Xu, H., Estrada, Y. D., Peng, X., Chen, M., Shah, N., Suarez-Farinas, M., Pavel, A. B., Nograles, K. & Guttman-Yassky, E., Jan 1 2019, In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Cellulitis
Placebos
Biomarkers
Safety
101 Citations (Scopus)

A pilot study of an oral phosphodiesterase inhibitor (apremilast) for atopic dermatitis in adults

Samrao, A., Berry, T. M., Goreshi, R. & Simpson, E., Aug 2012, In : Archives of Dermatology. 148, 8, p. 890-897 8 p.

Research output: Contribution to journalArticle

Phosphodiesterase Inhibitors
Atopic Dermatitis
Dermatology
Eczema
Quality of Life
111 Citations (Scopus)

A pilot study of emollient therapy for the primary prevention of atopic dermatitis

Simpson, E., Berry, T. M., Brown, P. A. & Hanifin, J., Oct 2010, In : Journal of the American Academy of Dermatology. 63, 4, p. 587-593 7 p.

Research output: Contribution to journalArticle

Emollients
Atopic Dermatitis
Primary Prevention
Skin
Therapeutics
27 Citations (Scopus)

A Pragmatic Approach to Patch Testing Atopic Dermatitis Patients: Clinical Recommendations Based on Expert Consensus Opinion

Chen, J. K., Jacob, S. E., Nedorost, S. T., Hanifin, J., Simpson, E., Boguniewicz, M., Watsky, K. L., Lugo-Somolinos, A., Hamann, C. R., Eberting, C. L., Silverberg, J. I. & Thyssen, J. P., Jul 1 2016, In : Dermatitis. 27, 4, p. 186-192 7 p.

Research output: Contribution to journalReview article

Expert Testimony
Atopic Dermatitis
Allergic Contact Dermatitis
Dermatitis
Patch Tests
4 Citations (Scopus)

A randomized controlled trial of an emollient with ceramide and filaggrin-associated amino acids for the primary prevention of atopic dermatitis in high-risk infants

McClanahan, D., Wong, A., Kezic, S., Samrao, A., Hajar, T., Hill, E. & Simpson, E. L., Nov 1 2019, In : Journal of the European Academy of Dermatology and Venereology. 33, 11, p. 2087-2094 8 p.

Research output: Contribution to journalArticle

Emollients
Ceramides
Atopic Dermatitis
Primary Prevention
Randomized Controlled Trials
17 Citations (Scopus)

Are biologics safe in the treatment of atopic dermatitis? A review with a focus on immediate hypersensitivity reactions

Bremmer, M. S., Bremmer, S. F., Baig-Lewis, S. & Simpson, E., Oct 2009, In : Journal of the American Academy of Dermatology. 61, 4, p. 666-676 11 p.

Research output: Contribution to journalArticle

Immediate Hypersensitivity
Atopic Dermatitis
Biological Products
Therapeutics
Biological Therapy
4 Citations (Scopus)

Are epidermal defects the key initiating factors in the development of atopic dermatitis?

Simpson, E., Dec 2010, In : British Journal of Dermatology. 163, 6, p. 1147-1148 2 p.

Research output: Contribution to journalArticle

Intermediate Filament Proteins
Animal Disease Models
Atopic Dermatitis
Epidermis
Mutation
15 Citations (Scopus)

Assessing the new and emerging treatments for atopic dermatitis

Eichenfield, L. F., Friedlander, S. F., Simpson, E. & Irvine, A. D., Jun 1 2016, In : Seminars in Cutaneous Medicine and Surgery. 35, p. 92S-96S

Research output: Contribution to journalArticle

Atopic Dermatitis
Cytokines
Type II Interleukin-4 Receptors
Immunoglobulin E
Phosphodiesterase 4 Inhibitors
44 Citations (Scopus)

Assessment of atopic dermatitis using self-report and caregiver report: A multicentre validation study

Silverberg, J. I., Patel, N., Immaneni, S., Rusniak, B., Silverberg, N. B., Debashis, R., Fewkes, N. & Simpson, E., Dec 1 2015, In : British Journal of Dermatology. 173, 6, p. 1400-1404 5 p.

Research output: Contribution to journalArticle

Validation Studies
Eczema
Atopic Dermatitis
Self Report
Caregivers
31 Citations (Scopus)

Association between obesity and eczema

Silverberg, J. I. & Simpson, E., 2014, In : Dermatitis. 25, 4, p. 172-181 10 p.

Research output: Contribution to journalArticle

Eczema
Obesity
Health
Odds Ratio
Confidence Intervals
120 Citations (Scopus)

Association between severe eczema in children and multiple comorbid conditions and increased healthcare utilization

Silverberg, J. I. & Simpson, E., Aug 2013, In : Pediatric Allergy and Immunology. 24, 5, p. 476-486 11 p.

Research output: Contribution to journalArticle

Eczema
Food Hypersensitivity
Atopic Dermatitis
Delivery of Health Care
Sleep
22 Citations (Scopus)

Association of atopic dermatitis with allergic, autoimmune, and cardiovascular comorbidities in US adults

Silverberg, J. I., Gelfand, J. M., Margolis, D. J., Boguniewicz, M., Fonacier, L., Grayson, M. H., Simpson, E., Ong, P. Y. & Chiesa Fuxench, Z. C., Nov 1 2018, In : Annals of Allergy, Asthma and Immunology. 121, 5, p. 604-612.e3

Research output: Contribution to journalArticle

Atopic Dermatitis
Comorbidity
Odds Ratio
Confidence Intervals
Food Hypersensitivity
11 Citations (Scopus)

Association of inadequately controlled disease and disease severity with patient-reported disease burden in adults with atopic dermatitis

Simpson, E., Guttman-Yassky, E., Margolis, D. J., Feldman, S. R., Qureshi, A., Hata, T., Mastey, V., Wei, W., Eckert, L., Chao, J., Arnold, R. J. G., Yu, T., Vekeman, F., Suárez-Fariñas, M. & Gadkari, A., Aug 1 2018, In : JAMA Dermatology. 154, 8, p. 903-912 10 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Sleep
Phototherapy
Anxiety
Quality of Life
80 Citations (Scopus)

Associations of childhood eczema severity: A US population-based study

Silverberg, J. I. & Simpson, E., 2014, In : Dermatitis. 25, 3, p. 107-114 8 p.

Research output: Contribution to journalArticle

Eczema
Population
Confidence Intervals
Mothers
Logistic Models

A survey in uncharted territory: A collaborative study to explore the approach to atopic dermatitis patient management in allopathy and naturopathy

Dhossche, J., Corn, J., Simpson, E. L. & Funk, T., Jan 1 2019, (Accepted/In press) In : Pediatric dermatology.

Research output: Contribution to journalArticle

Naturopathy
Atopic Dermatitis
Skin Care
Diet
Food
59 Citations (Scopus)

A systematic review of Investigator Global Assessment (IGA) in atopic dermatitis (AD) trials: Many options, no standards

Futamura, M., Leshem, Y. A., Thomas, K. S., Nankervis, H., Williams, H. C. & Simpson, E., Feb 1 2016, In : Journal of the American Academy of Dermatology. 74, 2, p. 288-294 7 p.

Research output: Contribution to journalReview article

Atopic Dermatitis
Research Personnel
Eczema
Randomized Controlled Trials
Databases
54 Citations (Scopus)

A systematic review of topical corticosteroid withdrawal ("steroid addiction") in patients with atopic dermatitis and other dermatoses

Hajar, T., Leshem, Y. A., Hanifin, J., Nedorost, S. T., Lio, P. A., Paller, A. S., Block, J. & Simpson, E., Mar 1 2015, In : Journal of the American Academy of Dermatology. 72, 3, p. 541-549.e2

Research output: Contribution to journalArticle

Atopic Dermatitis
Skin Diseases
Adrenal Cortex Hormones
Steroids
Social Media
96 Citations (Scopus)

Atopic dermatitis: A review of topical treatment options

Simpson, E., Mar 2010, In : Current Medical Research and Opinion. 26, 3, p. 633-640 8 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Adrenal Cortex Hormones
Therapeutics
Emollients
Skin
59 Citations (Scopus)

Atopic dermatitis

Simpson, E. & Hanifin, J., Jan 2006, In : Medical Clinics of North America. 90, 1, p. 149-167 19 p.

Research output: Contribution to journalArticle

Dermatitis
Atopic Dermatitis
Skin Diseases
Asthma
Eczema
3 Citations (Scopus)

Atopic dermatitis: Emerging therapies

Simpson, E., Udkoff, J., Borok, J., Tom, W., Beck, L. & Eichenfield, L. F., Sep 1 2017, In : Seminars in Cutaneous Medicine and Surgery. 36, 3, p. 124-130 7 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
United States Food and Drug Administration
Therapeutics
Cytokines
Inflammation
46 Citations (Scopus)

Atopic Dermatitis: Epidemiology and Pathogenesis Update

Eichenfield, L. F., Ellis, C. N., Mancini, A. J., Paller, A. S. & Simpson, E., Sep 2012, In : Seminars in Cutaneous Medicine and Surgery. 31, 3 SUPPL.

Research output: Contribution to journalArticle

Atopic Dermatitis
Epidemiology
Mutation
Research
Genes
59 Citations (Scopus)

Atopic dermatitis.

Simpson, E. & Hanifin, J., Jul 2005, In : Journal of the American Academy of Dermatology. 53, 1, p. 115-128 14 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
19 Citations (Scopus)

Atopic Dermatitis in America Study: A Cross-Sectional Study Examining the Prevalence and Disease Burden of Atopic Dermatitis in the US Adult Population

Chiesa Fuxench, Z. C., Block, J. K., Boguniewicz, M., Boyle, J., Fonacier, L., Gelfand, J. M., Grayson, M. H., Margolis, D. J., Mitchell, L., Silverberg, J. I., Schwartz, L., Simpson, E. & Ong, P. Y., Mar 1 2019, In : Journal of Investigative Dermatology. 139, 3, p. 583-590 8 p.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Cross-Sectional Studies
Population
Quality of Life
Anxiety
3 Citations (Scopus)

Atopic Dermatitis in US Adults: From Population to Health Care Utilization

Silverberg, J. I., Gelfand, J. M., Margolis, D. J., Boguniewicz, M., Fonacier, L., Grayson, M. H., Ong, P. Y., Chiesa Fuxench, Z. & Simpson, E., May 1 2019, In : Journal of Allergy and Clinical Immunology: In Practice. 7, 5, p. 1524-1532.e2

Research output: Contribution to journalArticle

Patient Acceptance of Health Care
Atopic Dermatitis
Population
Ambulatory Care
Hospital Emergency Service
17 Citations (Scopus)

Atopic dermatitis prevention

Simpson, E., Mar 2006, In : Dermatologic Therapy. 19, 2, p. 108-117 10 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Dermatology
Allergens
Medicine
Skin
Nephrogenic Fibrosing Dermopathy
Gadolinium
Tissue Donors
Transplant Recipients
55 Citations (Scopus)

Baricitinib in adult patients with moderate-to-severe atopic dermatitis: A phase 2 parallel, double-blinded, randomized placebo-controlled multiple-dose study

Guttman-Yassky, E., Silverberg, J. I., Nemoto, O., Forman, S. B., Wilke, A., Prescilla, R., de la Peña, A., Nunes, F. P., Janes, J., Gamalo, M., Donley, D., Paik, J., DeLozier, A. M., Nickoloff, B. J. & Simpson, E., Apr 1 2019, In : Journal of the American Academy of Dermatology. 80, 4, p. 913-921.e9

Research output: Contribution to journalArticle

Atopic Dermatitis
Placebos
Adrenal Cortex Hormones
Pruritus
Random Allocation

Biologics for the treatment of atopic dermatitis

Hajar, T., Hill, E. & Simpson, E., Jan 2 2018, Biologic and Systemic Agents in Dermatology. Springer International Publishing, p. 309-317 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Atopic Dermatitis
Biological Products
17 Citations (Scopus)

CD30 expression on CD1a+ and CD8+ cells in atopic dermatitis and correlation with disease severity

Oflazoglu, E., Simpson, E., Takiguchi, R., Grewal, I. S., Hanifin, J. & Gerber, H. P., Jan 2008, In : European Journal of Dermatology. 18, 1, p. 41-49 9 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
T-Lymphocytes
Langerhans Cells
Immunoglobulin E
Serum
3 Citations (Scopus)

CD40 expression on antigen presenting cells and correlation with disease severity in atopic dermatitis

Oflazoglu, E., Simpson, E., Takiguchi, R., Hanifin, J., Grewal, I. S. & Gerber, H. P., Sep 2008, In : European Journal of Dermatology. 18, 5, p. 527-533 7 p.

Research output: Contribution to journalArticle

Antigen-Presenting Cells
Atopic Dermatitis
Skin
Immunoglobulin E
CD11b Antigens
21 Citations (Scopus)

Cell death-induced activation of epidermal growth factor receptor in keratinocytes: Implications for restricting epidermal damage in dermatitis

Iordanov, M. S., Sundholm, A. J., Simpson, E., Hanifin, J., Ryabinina, O. P., Choi, R. J., Korcheva, V., Schneider, P. & Magun, B. E., Jul 2005, In : Journal of Investigative Dermatology. 125, 1, p. 134-142 9 p.

Research output: Contribution to journalArticle

Dermatitis
Cell death
Keratinocytes
Epidermal Growth Factor Receptor
Cell Death

Cellular pattern recognition towards discrimination of normal skin from melanoma in non-invasive confocal imaging

Swerdlin, A., Simpson, E., Jacques, S. & Gareau, D. S., 2012, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8214. 82140C

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Keratinocytes
pattern recognition
Pattern recognition
discrimination
Melanoma
1 Citation (Scopus)

Clearing up misunderstandings around core outcomes for atopic dermatitis

Williams, H. C., Apfelbacher, C., Chalmers, J. R., Schmitt, J., Simpson, E., Spuls, P. I. & Thomas, K. S., Aug 1 2015, In : British Journal of Dermatology. 173, 2, p. 623-624 2 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
125 Citations (Scopus)

Climatic factors are associated with childhood eczema prevalence in the United States

Silverberg, J. I., Hanifin, J. & Simpson, E., Jul 2013, In : Journal of Investigative Dermatology. 133, 7, p. 1752-1759 8 p.

Research output: Contribution to journalArticle

Eczema
Atopic Dermatitis
Humidity
Atmospheric humidity
Allergies
17 Citations (Scopus)
Ichthyosis Vulgaris
Atopic Dermatitis
Odds Ratio
Age of Onset
Causality

Clinically Meaningful Responses to Dupilumab in Adolescents with Uncontrolled Moderate-to-Severe Atopic Dermatitis: Post-hoc Analyses from a Randomized Clinical Trial

Paller, A. S., Bansal, A., Simpson, E. L., Boguniewicz, M., Blauvelt, A., Siegfried, E. C., Guttman-Yassky, E., Hultsch, T., Chen, Z., Mina-Osorio, P., Lu, Y., Rossi, A. B., He, X., Kamal, M., Graham, N. M. H., Pirozzi, G., Ruddy, M., Eckert, L. & Gadkari, A., Jan 1 2019, (Accepted/In press) In : American Journal of Clinical Dermatology.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Randomized Controlled Trials
Placebos
Quality of Life
Signs and Symptoms
36 Citations (Scopus)

Comorbidity in Atopic Dermatitis

Simpson, E., Jan 1 2012, In : Current Dermatology Reports. 1, 1, p. 29-38 10 p.

Research output: Contribution to journalReview article

Open Access
Atopic Dermatitis
Comorbidity
Skin
Mental Health
Genetic Research

Conceptual Model to Illustrate the Symptom Experience and Humanistic Burden Associated with Atopic Dermatitis in Adults and Adolescents

Grant, L., Seiding Larsen, L., Trennery, C., Silverberg, J. I., Abramovits, W., Simpson, E., Stalder, J. F., Paty, J., Hahn-Pedersen, J., Kragh, N., Bang, B. & Arbuckle, R., Jul 1 2019, In : Dermatitis. 30, 4, p. 247-254 8 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Quality of Life
Signs and Symptoms
Eczema
Erythema
27 Citations (Scopus)

Conjunctivitis in dupilumab clinical trials

Akinlade, B., Guttman-Yassky, E., de Bruin-Weller, M., Simpson, E., Blauvelt, A., Cork, M. J., Prens, E., Asbell, P., Akpek, E., Corren, J., Bachert, C., Hirano, I., Weyne, J., Korotzer, A., Chen, Z., Hultsch, T., Zhu, X., Davis, J. D., Mannent, L., Hamilton, J. D. & 8 others, Teper, A., Staudinger, H., Rizova, E., Pirozzi, G., Graham, N. M. H., Shumel, B., Ardeleanu, M. & Wollenberg, A., Jan 1 2019, In : British Journal of Dermatology.

Research output: Contribution to journalArticle

Open Access
Conjunctivitis
Atopic Dermatitis
Clinical Trials
Placebos
Incidence
10 Citations (Scopus)

Content and construct validity, predictors, and distribution of self-reported atopic dermatitis severity in US adults

Silverberg, J. I., Chiesa Fuxench, Z. C., Gelfand, J. M., Margolis, D. J., Boguniewicz, M., Fonacier, L., Grayson, M. H., Simpson, E. & Ong, P. Y., Jan 1 2018, (Accepted/In press) In : Annals of Allergy, Asthma and Immunology.

Research output: Contribution to journalArticle

Atopic Dermatitis
Eczema
Anxiety
Depression
Pain
3 Citations (Scopus)

Crisaborole Ointment Improves Quality of Life of Patients with Mild to Moderate Atopic Dermatitis and Their Families

Simpson, E., Paller, A. S., Boguniewicz, M., Eichenfield, L. F., Feldman, S. R., Silverberg, J. I., Chamlin, S. L. & Zane, L. T., Dec 1 2018, In : Dermatology and Therapy. 8, 4, p. 605-619 15 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Ointments
Quality of Life
Dermatology
Caregivers
14 Citations (Scopus)

Current Issues in Atopic Comorbidities and Preventing the Atopic March

Simpson, E., Eichenfield, L. F., Ellis, C. N., Mancini, A. J. & Paller, A. S., Sep 2012, In : Seminars in Cutaneous Medicine and Surgery. 31, 3 SUPPL.

Research output: Contribution to journalArticle

Atopic Dermatitis
Comorbidity
Skin
Family Health
Mental Disorders
6 Citations (Scopus)

Cutaneous responses to vaccinia in individuals with previous smallpox vaccination

Simpson, E., Hercher, M., Hammarlund, E. K., Lewis, M. W., Slifka, M. & Hanifin, J., Sep 2007, In : Journal of the American Academy of Dermatology. 57, 3, p. 442-444 3 p.

Research output: Contribution to journalArticle

Vaccinia
Smallpox
Vaccination
Smallpox Vaccine
Skin
7 Citations (Scopus)

Developing drugs for treatment of atopic dermatitis in children (≥3 months to <18 years of age): Draft guidance for industry

Siegfried, E. C., Jaworski, J. C., Eichenfield, L. F., Paller, A., Hebert, A. A., Simpson, E., Altman, E., Arena, C., Blauvelt, A., Block, J., Boguniewicz, M., Chen, S., Cordoro, K., Hanna, D., Horii, K., Hultsch, T., Lee, J., Leung, D. Y., Lio, P., Milner, J. & 13 others, Omachi, T., Schneider, C., Schneider, L., Sidbury, R., Smith, T., Sugarman, J., Taha, S., Tofte, S., Tollefson, M., Tom, W. L., West, D. P., Whitney, L. & Zane, L., May 1 2018, In : Pediatric Dermatology. 35, 3, p. 303-322 20 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Industry
United States Food and Drug Administration
Clinical Trials
Pharmaceutical Preparations