Eric Simpson

Professor

  • 7419 Citations
  • 43 h-Index
20012019
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Research Output 2001 2019

2019

Alopecia areata in 2 patients treated with dupilumab: New onset and worsening

Chung, J., Slaught, C. L. & Simpson, E., Aug 1 2019, In : JAAD Case Reports. 5, 8, p. 643-645 3 p.

Research output: Contribution to journalArticle

Open Access
Alopecia Areata
Atopic Dermatitis
Alopecia Areata 2
SAR231893
15 Citations (Scopus)

A Phase 2 Randomized Trial of Apremilast in Patients with Atopic Dermatitis

Simpson, E., Imafuku, S., Poulin, Y., Ungar, B., Zhou, L., Malik, K., Wen, H. C., Xu, H., Estrada, Y. D., Peng, X., Chen, M., Shah, N., Suarez-Farinas, M., Pavel, A. B., Nograles, K. & Guttman-Yassky, E., Jan 1 2019, In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Cellulitis
Placebos
Biomarkers
Safety
2 Citations (Scopus)

A randomized controlled trial of an emollient with ceramide and filaggrin-associated amino acids for the primary prevention of atopic dermatitis in high-risk infants

McClanahan, D., Wong, A., Kezic, S., Samrao, A., Hajar, T., Hill, E. & Simpson, E. L., Nov 1 2019, In : Journal of the European Academy of Dermatology and Venereology. 33, 11, p. 2087-2094 8 p.

Research output: Contribution to journalArticle

Emollients
Ceramides
Atopic Dermatitis
Primary Prevention
Randomized Controlled Trials

A survey in uncharted territory: A collaborative study to explore the approach to atopic dermatitis patient management in allopathy and naturopathy

Dhossche, J., Corn, J., Simpson, E. L. & Funk, T., Jan 1 2019, (Accepted/In press) In : Pediatric dermatology.

Research output: Contribution to journalArticle

Naturopathy
Atopic Dermatitis
Skin Care
Diet
Food
18 Citations (Scopus)

Atopic Dermatitis in America Study: A Cross-Sectional Study Examining the Prevalence and Disease Burden of Atopic Dermatitis in the US Adult Population

Chiesa Fuxench, Z. C., Block, J. K., Boguniewicz, M., Boyle, J., Fonacier, L., Gelfand, J. M., Grayson, M. H., Margolis, D. J., Mitchell, L., Silverberg, J. I., Schwartz, L., Simpson, E. & Ong, P. Y., Mar 1 2019, In : Journal of Investigative Dermatology. 139, 3, p. 583-590 8 p.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Cross-Sectional Studies
Population
Quality of Life
Anxiety
1 Citation (Scopus)

Atopic Dermatitis in US Adults: From Population to Health Care Utilization

Silverberg, J. I., Gelfand, J. M., Margolis, D. J., Boguniewicz, M., Fonacier, L., Grayson, M. H., Ong, P. Y., Chiesa Fuxench, Z. & Simpson, E., May 1 2019, In : Journal of Allergy and Clinical Immunology: In Practice. 7, 5, p. 1524-1532.e2

Research output: Contribution to journalArticle

Patient Acceptance of Health Care
Atopic Dermatitis
Population
Ambulatory Care
Hospital Emergency Service
52 Citations (Scopus)

Baricitinib in adult patients with moderate-to-severe atopic dermatitis: A phase 2 parallel, double-blinded, randomized placebo-controlled multiple-dose study

Guttman-Yassky, E., Silverberg, J. I., Nemoto, O., Forman, S. B., Wilke, A., Prescilla, R., de la Peña, A., Nunes, F. P., Janes, J., Gamalo, M., Donley, D., Paik, J., DeLozier, A. M., Nickoloff, B. J. & Simpson, E., Apr 1 2019, In : Journal of the American Academy of Dermatology. 80, 4, p. 913-921.e9

Research output: Contribution to journalArticle

Atopic Dermatitis
Placebos
Adrenal Cortex Hormones
Pruritus
Random Allocation

Clinically Meaningful Responses to Dupilumab in Adolescents with Uncontrolled Moderate-to-Severe Atopic Dermatitis: Post-hoc Analyses from a Randomized Clinical Trial

Paller, A. S., Bansal, A., Simpson, E. L., Boguniewicz, M., Blauvelt, A., Siegfried, E. C., Guttman-Yassky, E., Hultsch, T., Chen, Z., Mina-Osorio, P., Lu, Y., Rossi, A. B., He, X., Kamal, M., Graham, N. M. H., Pirozzi, G., Ruddy, M., Eckert, L. & Gadkari, A., Jan 1 2019, (Accepted/In press) In : American Journal of Clinical Dermatology.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Randomized Controlled Trials
Placebos
Quality of Life
Signs and Symptoms

Conceptual Model to Illustrate the Symptom Experience and Humanistic Burden Associated with Atopic Dermatitis in Adults and Adolescents

Grant, L., Seiding Larsen, L., Trennery, C., Silverberg, J. I., Abramovits, W., Simpson, E., Stalder, J. F., Paty, J., Hahn-Pedersen, J., Kragh, N., Bang, B. & Arbuckle, R., Jul 1 2019, In : Dermatitis. 30, 4, p. 247-254 8 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Quality of Life
Signs and Symptoms
Eczema
Erythema
23 Citations (Scopus)

Conjunctivitis in dupilumab clinical trials

Akinlade, B., Guttman-Yassky, E., de Bruin-Weller, M., Simpson, E., Blauvelt, A., Cork, M. J., Prens, E., Asbell, P., Akpek, E., Corren, J., Bachert, C., Hirano, I., Weyne, J., Korotzer, A., Chen, Z., Hultsch, T., Zhu, X., Davis, J. D., Mannent, L., Hamilton, J. D. & 8 others, Teper, A., Staudinger, H., Rizova, E., Pirozzi, G., Graham, N. M. H., Shumel, B., Ardeleanu, M. & Wollenberg, A., Jan 1 2019, In : British Journal of Dermatology.

Research output: Contribution to journalArticle

Open Access
Conjunctivitis
Atopic Dermatitis
Clinical Trials
Placebos
Incidence
1 Citation (Scopus)
Atopic Dermatitis
Signs and Symptoms
Surveys and Questionnaires
Patient Reported Outcome Measures
Interviews

Direct and Indirect Effects of Crisaborole Ointment on Quality of Life in Patients with Atopic Dermatitis: A Mediation Analysis

Simpson, E., Yosipovitch, G., Bushmakin, A. G., Cappelleri, J. C., Luger, T., Ständer, S., Tom, W. L., Ports, W. C., Zielinski, M. A., Tallman, A. M., Tan, H. & Gerber, R. A., Jul 1 2019, In : Acta dermato-venereologica. 99, 9, p. 756-761 6 p.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Ointments
Pruritus
Quality of Life
Dermatology
4 Citations (Scopus)

Distribution of atopic dermatitis lesions in United States adults

Silverberg, J. I., Margolis, D. J., Boguniewicz, M., Fonacier, L., Grayson, M. H., Ong, P. Y., Chiesa Fuxench, Z. C., Simpson, E. & Gelfand, J. M., Jan 1 2019, In : Journal of the European Academy of Dermatology and Venereology.

Research output: Contribution to journalArticle

Atopic Dermatitis
Quality of Life
Dermatology
Buttocks
Phenotype
8 Citations (Scopus)

Dupilumab does not affect correlates of vaccine-induced immunity: A randomized, placebo-controlled trial in adults with moderate-to-severe atopic dermatitis

Blauvelt, A., Simpson, E., Tyring, S. K., Purcell, L. A., Shumel, B., Petro, C. D., Akinlade, B., Gadkari, A., Eckert, L., Graham, N. M. H., Pirozzi, G. & Evans, R., Jan 1 2019, In : Journal of the American Academy of Dermatology. 80, 1, p. 158-167.e1

Research output: Contribution to journalArticle

Atopic Dermatitis
Immunity
Vaccines
Randomized Controlled Trials
Placebos

Dupilumab improves patient-reported symptoms of atopic dermatitis, symptoms of anxiety and depression, and health-related quality of life in moderate-to-severe atopic dermatitis: analysis of pooled data from the randomized trials SOLO 1 and SOLO 2

Cork, M. J., Eckert, L., Simpson, E., Armstrong, A., Barbarot, S., Puig, L., Girolomoni, G., de Bruin-Weller, M., Wollenberg, A., Kataoka, Y., Remitz, A., Beissert, S., Mastey, V., Ardeleanu, M., Chen, Z., Gadkari, A. & Chao, J., Jan 1 2019, In : Journal of Dermatological Treatment.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Anxiety
Quality of Life
Depression
Pruritus
6 Citations (Scopus)

Dupilumab provides important clinical benefits to patients with atopic dermatitis who do not achieve clear or almost clear skin according to the Investigator's Global Assessment: a pooled analysis of data from two phase III trials

Silverberg, J. I., Simpson, E., Ardeleanu, M., Thaçi, D., Barbarot, S., Bagel, J., Chen, Z., Eckert, L., Chao, J., Korotzer, A., Rizova, E., Rossi, A. B., Lu, Y., Graham, N. M. H., Hultsch, T., Pirozzi, G. & Akinlade, B., Jul 1 2019, In : British Journal of Dermatology. 181, 1, p. 80-87 8 p.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Research Personnel
Skin
Eczema
Placebos

Evaluating patient-perceived control of atopic dermatitis: design, validation, and scoring of the Atopic Dermatitis Control Tool (ADCT)

Pariser, D. M., Simpson, E. L., Gadkari, A., Bieber, T., Margolis, D. J., Brown, M., Nelson, L., Mahajan, P., Reaney, M., Guillemin, I., Mallya, U. G. & Eckert, L., Jan 1 2019, (Accepted/In press) In : Current Medical Research and Opinion.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Aptitude
Qualitative Research
United States Food and Drug Administration
Psychometrics
7 Citations (Scopus)

Health Utility Scores of Atopic Dermatitis in US Adults

Silverberg, J. I., Gelfand, J. M., Margolis, D. J., Boguniewicz, M., Fonacier, L., Grayson, M. H., Ong, P. Y., Fuxench, Z. C. & Simpson, E., Jan 1 2019, (Accepted/In press) In : Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journalArticle

Atopic Dermatitis
Health
Quality-Adjusted Life Years
Population
Comorbidity
3 Citations (Scopus)

Improvement of atopic dermatitis with dupilumab occurs equally well across different anatomical regions: data from phase III clinical trials

Blauvelt, A., Rosmarin, D., Bieber, T., Simpson, E., Bagel, J., Worm, M., Deleuran, M., Katoh, N., Kawashima, M., Shumel, B., Chen, Z., Rossi, A. B., Hultsch, T. & Ardeleanu, M., Jul 1 2019, In : British Journal of Dermatology. 181, 1, p. 196-197 2 p.

Research output: Contribution to journalLetter

Open Access
Phase III Clinical Trials
Atopic Dermatitis
SAR231893
6 Citations (Scopus)

Infections in Dupilumab Clinical Trials in Atopic Dermatitis: A Comprehensive Pooled Analysis

Eichenfield, L. F., Bieber, T., Beck, L. A., Simpson, E., Thaçi, D., de Bruin-Weller, M., Deleuran, M., Silverberg, J. I., Ferrandiz, C., Fölster-Holst, R., Chen, Z., Graham, N. M. H., Pirozzi, G., Akinlade, B., Yancopoulos, G. D. & Ardeleanu, M., Jun 1 2019, In : American Journal of Clinical Dermatology. 20, 3, p. 443-456 14 p.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Clinical Trials
Infection
Placebos
Odds Ratio
1 Citation (Scopus)

Kotatsu-induced erythema ab igne

Baltazar, D., Brockman, R. & Simpson, E., Mar 1 2019, In : Anais brasileiros de dermatologia. 94, 2, p. 253-254 2 p.

Research output: Contribution to journalLetter

Open Access
Erythema
1 Citation (Scopus)

Laboratory safety of dupilumab in moderate-to-severe atopic dermatitis: results from three phase III trials (LIBERTY AD SOLO 1, LIBERTY AD SOLO 2, LIBERTY AD CHRONOS)

Wollenberg, A., Beck, L. A., Blauvelt, A., Simpson, E. L., Chen, Z., Chen, Q., Shumel, B., Khokhar, F. A., Hultsch, T., Rizova, E., Rossi, A. B., Graham, N. M. H., Pirozzi, G., Lu, Y. & Ardeleanu, M., Jan 1 2019, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Safety
Type II Interleukin-4 Receptors
Placebos
Urinalysis
2 Citations (Scopus)

Measurement Properties of the Hospital Anxiety and Depression Scale Used in Atopic Dermatitis in Adults

Silverberg, J. I., Gelfand, J. M., Margolis, D. J., Boguniewicz, M., Fonacier, L., Grayson, M. H., Ong, P. Y., Chiesa Fuxench, Z. C. & Simpson, E., Jan 1 2019, In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

Atopic Dermatitis
Anxiety
Depression
1 Citation (Scopus)

Navigating the landscape of core outcome set development in dermatology

Prinsen, C. A. C., Spuls, P. I., Kottner, J., Thomas, K. S., Apfelbacher, C., Chalmers, J. R., Deckert, S., Furue, M., Gerbens, L., Kirkham, J., Simpson, E., Alam, M., Balzer, K., Beeckman, D., Eleftheriadou, V., Ezzedine, K., Horbach, S. E. R., Ingram, J. R., Layton, A. M., Weller, K. & 4 others, Wild, T., Wolkerstorfer, A., Williams, H. C. & Schmitt, J., Jul 1 2019, In : Journal of the American Academy of Dermatology. 81, 1, p. 297-305 9 p.

Research output: Contribution to journalArticle

Dermatology
Skin Diseases
Research Personnel
Outcome Assessment (Health Care)
Databases
3 Citations (Scopus)

Pain Is a Common and Burdensome Symptom of Atopic Dermatitis in United States Adults

Silverberg, J. I., Gelfand, J. M., Margolis, D. J., Boguniewicz, M., Fonacier, L., Grayson, M. H., Chiesa Fuxench, Z. C., Simpson, E. & Ong, P. Y., Jan 1 2019, In : Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journalArticle

Atopic Dermatitis
Pain
Skin
Eczema

Patient-reported outcomes of adalimumab, phototherapy, and placebo in the Vascular Inflammation in Psoriasis Trial: A randomized controlled study

Noe, M. H., Wan, M. T., Shin, D. B., Armstrong, A. W., Duffin, K. C., Chiesa Fuxench, Z. C., Kalb, R. E., Menter, A., Simpson, E., Takeshita, J., Tyring, S. K., Van Voorhees, A. S., Mehta, N. N. & Gelfand, J. M., Jan 1 2019, (Accepted/In press) In : Journal of the American Academy of Dermatology.

Research output: Contribution to journalArticle

Phototherapy
Psoriasis
Blood Vessels
Randomized Controlled Trials
Placebos
7 Citations (Scopus)

Report from the National Institute of Allergy and Infectious Diseases workshop on “Atopic dermatitis and the atopic march: Mechanisms and interventions”

Davidson, W. F., Leung, D. Y. M., Beck, L. A., Berin, C. M., Boguniewicz, M., Busse, W. W., Chatila, T. A., Geha, R. S., Gern, J. E., Guttman-Yassky, E., Irvine, A. D., Kim, B. S., Kong, H. H., Lack, G., Nadeau, K. C., Schwaninger, J., Simpson, A., Simpson, E., Spergel, J. M., Togias, A. & 5 others, Wahn, U., Wood, R. A., Woodfolk, J. A., Ziegler, S. F. & Plaut, M., Jan 1 2019, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

National Institute of Allergy and Infectious Diseases (U.S.)
Atopic Dermatitis
Food Hypersensitivity
Education
National Institutes of Health (U.S.)

Responder Threshold for Patient-Oriented Eczema Measure (POEM) and Children’s Dermatology Life Quality Index (CDLQI) in Adolescents with Atopic Dermatitis

Simpson, E. L., de Bruin-Weller, M., Eckert, L., Whalley, D., Guillemin, I., Reaney, M., Chen, Z., Nelson, L., Qin, S., Bansal, A. & Gadkari, A., Dec 1 2019, In : Dermatology and Therapy. 9, 4, p. 799-805 7 p.

Research output: Contribution to journalArticle

Open Access
Eczema
Atopic Dermatitis
Dermatology
Quality of Life
Research Personnel
20 Citations (Scopus)
Open Access
Atopic Dermatitis
Monoclonal Antibodies
Placebos
Clinical Trials
Adrenal Cortex Hormones
2 Citations (Scopus)

The burden of childhood atopic dermatitis in the primary care setting: A report from the meta-LARC consortium

Al-Naqeeb, J., Danner, S., Fagnan, L., Ramsey, K., Michaels, L. A., Mitchell, J., Branca, K., Morris, C., Nease, D. E., Zittleman, L., Levy, B., Daly, J., Hahn, D., Dolor, R. J., Williams, H. C., Chalmers, J. R., Hanifin, J., Tofte, S., Zuckerman, K., Hansis, K. & 9 others, Gundersen, M., Block, J., Karr, F., Dunbrasky, S., Siebe, K., Dillon, K., Cibotti, R., Lapidus, J. & Simpson, E., Jan 1 2019, In : Journal of the American Board of Family Medicine. 32, 2, p. 191-200 10 p.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Primary Health Care
Skin Care
Oils
Water
3 Citations (Scopus)

The socioeconomics of atopic dermatitis

Chung, J. & Simpson, E., Jan 1 2019, In : Annals of Allergy, Asthma and Immunology.

Research output: Contribution to journalReview article

Atopic Dermatitis
Social Class
Costs and Cost Analysis
Career Choice
Absenteeism
1 Citation (Scopus)

Validation and Interpretation of Short Form 12 and Comparison with Dermatology Life Quality Index in Atopic Dermatitis in Adults

Silverberg, J. I., Gelfand, J. M., Margolis, D. J., Boguniewicz, M., Fonacier, L., Grayson, M. H., Ong, P. Y., Chiesa Fuxench, Z. C. & Simpson, E., Jan 1 2019, In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

Dermatology
Atopic Dermatitis
Quality of Life
Analysis of variance (ANOVA)
Eczema
1 Citation (Scopus)

Validation of a novel smartphone application-enabled, patient-operated skin barrier device

Grinich, E. E., Shah, A. V. & Simpson, E., Jan 1 2019, In : Skin Research and Technology.

Research output: Contribution to journalArticle

Cornea
Equipment and Supplies
Skin
Water
Research Personnel
1 Citation (Scopus)

Validation of the Atopic Dermatitis Control Tool (ADCT©) using a longitudinal survey of biologic-treated patients with atopic dermatitis

Simpson, E., Eckert, L., Gadkari, A., Mallya, U. G., Yang, M., Nelson, L., Brown, M., Reaney, M., Mahajan, P., Guillemin, I., Boguniewicz, M. & Pariser, D., Nov 6 2019, In : BMC Dermatology. 19, 1, 15.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Biological Products
Longitudinal Studies
2018
21 Citations (Scopus)

Association of atopic dermatitis with allergic, autoimmune, and cardiovascular comorbidities in US adults

Silverberg, J. I., Gelfand, J. M., Margolis, D. J., Boguniewicz, M., Fonacier, L., Grayson, M. H., Simpson, E., Ong, P. Y. & Chiesa Fuxench, Z. C., Nov 1 2018, In : Annals of Allergy, Asthma and Immunology. 121, 5, p. 604-612.e3

Research output: Contribution to journalArticle

Atopic Dermatitis
Comorbidity
Odds Ratio
Confidence Intervals
Food Hypersensitivity
8 Citations (Scopus)

Association of inadequately controlled disease and disease severity with patient-reported disease burden in adults with atopic dermatitis

Simpson, E., Guttman-Yassky, E., Margolis, D. J., Feldman, S. R., Qureshi, A., Hata, T., Mastey, V., Wei, W., Eckert, L., Chao, J., Arnold, R. J. G., Yu, T., Vekeman, F., Suárez-Fariñas, M. & Gadkari, A., Aug 1 2018, In : JAMA Dermatology. 154, 8, p. 903-912 10 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Sleep
Phototherapy
Anxiety
Quality of Life

Biologics for the treatment of atopic dermatitis

Hajar, T., Hill, E. & Simpson, E., Jan 2 2018, Biologic and Systemic Agents in Dermatology. Springer International Publishing, p. 309-317 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Atopic Dermatitis
Biological Products
10 Citations (Scopus)

Content and construct validity, predictors, and distribution of self-reported atopic dermatitis severity in US adults

Silverberg, J. I., Chiesa Fuxench, Z. C., Gelfand, J. M., Margolis, D. J., Boguniewicz, M., Fonacier, L., Grayson, M. H., Simpson, E. & Ong, P. Y., Jan 1 2018, (Accepted/In press) In : Annals of Allergy, Asthma and Immunology.

Research output: Contribution to journalArticle

Atopic Dermatitis
Eczema
Anxiety
Depression
Pain
3 Citations (Scopus)

Crisaborole Ointment Improves Quality of Life of Patients with Mild to Moderate Atopic Dermatitis and Their Families

Simpson, E., Paller, A. S., Boguniewicz, M., Eichenfield, L. F., Feldman, S. R., Silverberg, J. I., Chamlin, S. L. & Zane, L. T., Dec 1 2018, In : Dermatology and Therapy. 8, 4, p. 605-619 15 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Ointments
Quality of Life
Dermatology
Caregivers
7 Citations (Scopus)

Developing drugs for treatment of atopic dermatitis in children (≥3 months to <18 years of age): Draft guidance for industry

Siegfried, E. C., Jaworski, J. C., Eichenfield, L. F., Paller, A., Hebert, A. A., Simpson, E., Altman, E., Arena, C., Blauvelt, A., Block, J., Boguniewicz, M., Chen, S., Cordoro, K., Hanna, D., Horii, K., Hultsch, T., Lee, J., Leung, D. Y., Lio, P., Milner, J. & 13 others, Omachi, T., Schneider, C., Schneider, L., Sidbury, R., Smith, T., Sugarman, J., Taha, S., Tofte, S., Tollefson, M., Tom, W. L., West, D. P., Whitney, L. & Zane, L., May 1 2018, In : Pediatric Dermatology. 35, 3, p. 303-322 20 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Industry
United States Food and Drug Administration
Clinical Trials
Pharmaceutical Preparations
27 Citations (Scopus)

Effect of 2 psoriasis treatments on vascular inflammation and novel inflammatory cardiovascular biomarkers: A randomized placebo-controlled trial

Mehta, N. N., Shin, D. B., Joshi, A. A., Dey, A. K., Armstrong, A. W., Duffin, K. C., Fuxench, Z. C., Harrington, C. L., Hubbard, R. A., Kalb, R. E., Menter, A., Rader, D. J., Reilly, M. P., Simpson, E., Takeshita, J., Torigian, D. A., Werner, T. J., Troxel, A. B., Tyring, S. K., Vanderbeek, S. B. & 5 others, Van Voorhees, A. S., Playford, M. P., Ahlman, M. A., Alavi, A. & Gelfand, J. M., Jun 1 2018, In : Circulation: Cardiovascular Imaging. 11, 6, e007394.

Research output: Contribution to journalArticle

Psoriasis
Blood Vessels
Randomized Controlled Trials
Biomarkers
Placebos
1 Citation (Scopus)

Efficacy and safety of dupilumab for the treatment of moderate-to-severe atopic dermatitis in adults: A pooled analysis of two phase 2 clinical trials

Tofte, S., Papp, K., Sadick, N., Bohnert, K., Simpson, E., Thaçi, D., Bieber, T., Blauvelt, A., Sofen, H., Gooderham, M., Chen, Z., Gadkari, A., Eckert, L., Graham, N. M. H., Pirozzi, G. & Ardeleanu, M., Sep 1 2018, In : Journal of the American Association of Nurse Practitioners. 30, 9, p. 529-541 13 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Clinical Trials
Safety
Pruritus
Sleep
74 Citations (Scopus)

Efficacy and safety of lebrikizumab (an anti-IL-13 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical corticosteroids: A randomized, placebo-controlled phase II trial (TREBLE)

Simpson, E., Flohr, C., Eichenfield, L. F., Bieber, T., Sofen, H., Taïeb, A., Owen, R., Putnam, W., Castro, M., DeBusk, K., Lin, C. Y., Voulgari, A., Yen, K. & Omachi, T. A., Jan 1 2018, (Accepted/In press) In : Journal of the American Academy of Dermatology.

Research output: Contribution to journalArticle

Interleukin-13
Atopic Dermatitis
Adrenal Cortex Hormones
Monoclonal Antibodies
Placebos
24 Citations (Scopus)

Emollient use alters skin barrier and microbes in infants at risk for developing atopic dermatitis

Glatz, M., Jo, J. H., Kennedy, E. A., Polley, E. C., Segre, J. A., Simpson, E. & Kong, H. H., Feb 1 2018, In : PLoS One. 13, 2, e0192443.

Research output: Contribution to journalArticle

Emollients
atopic dermatitis
Streptococcus salivarius
Atopic Dermatitis
Skin
76 Citations (Scopus)

Epidemiology of atopic dermatitis in adults: Results from an international survey

Barbarot, S., Auziere, S., Gadkari, A., Girolomoni, G., Puig, L., Simpson, E., Margolis, D. J., de Bruin-Weller, M. & Eckert, L., Jun 1 2018, In : Allergy: European Journal of Allergy and Clinical Immunology. 73, 6, p. 1284-1293 10 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Epidemiology
Canada
Japan
Surveys and Questionnaires

Initial validation of the Burden of Disease in Atopic Eczema instrument, a quality-of-life measure for adult atopic dermatitis

Wang, A. R., Dunlap, R. R., Darwish, M. A., Simpson, E., Hanifin, J., Qureshi, A. A., Du, L. & Drucker, A. M., May 1 2018, In : British Journal of Dermatology. 178, 5, p. 1211-1212 2 p.

Research output: Contribution to journalLetter

Atopic Dermatitis
Quality of Life
14 Citations (Scopus)

Major Comorbidities of Atopic Dermatitis: Beyond Allergic Disorders

Paller, A., Jaworski, J. C., Simpson, E., Boguniewicz, M., Russell, J. J., Block, J. K., Tofte, S., Dunn, J. D., Feldman, S. R., Clark, A. R., Schwartz, G. & Eichenfield, L. F., Dec 1 2018, In : American Journal of Clinical Dermatology. 19, 6, p. 821-838 18 p.

Research output: Contribution to journalReview article

Atopic Dermatitis
Comorbidity
Skin
Alopecia Areata
Immune System Diseases
36 Citations (Scopus)

Patient burden and quality of life in atopic dermatitis in US adults: A population-based cross-sectional study

Silverberg, J. I., Gelfand, J. M., Margolis, D. J., Boguniewicz, M., Fonacier, L., Grayson, M. H., Simpson, E., Ong, P. Y. & Chiesa Fuxench, Z. C., Sep 1 2018, In : Annals of Allergy, Asthma and Immunology. 121, 3, p. 340-347 8 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Cross-Sectional Studies
Quality of Life
Population
Dermatology
25 Citations (Scopus)

Patients with Atopic Dermatitis Colonized with Staphylococcus aureus Have a Distinct Phenotype and Endotype

Simpson, E., Villarreal, M., Jepson, B., Rafaels, N., David, G., Hanifin, J., Taylor, P., Boguniewicz, M., Yoshida, T., De Benedetto, A., Barnes, K. C., Leung, D. Y. M. & Beck, L. A., Jan 1 2018, (Accepted/In press) In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

Atopic Dermatitis
Staphylococcus aureus
Phenotype
Biomarkers
L-Lactate Dehydrogenase
19 Citations (Scopus)

Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative)

Chalmers, J. R., Thomas, K. S., Apfelbacher, C., Williams, H. C., Prinsen, C. A., Spuls, P. I., Simpson, E., Gerbens, L. A. A., Boers, M., Barbarot, S., Stalder, J. F., Abuabara, K., Aoki, V., Ardeleanu, M., Armstrong, J., Bang, B., Berents, T. L., Burton, T., Butler, L., Chubachi, T. & 49 others, Cresswell-Melville, A., DeLozier, A., Eckert, L., Eichenfield, L., Flohr, C., Futamura, M., Gadkari, A., Gjerde, E. S., van Halewijn, K. F., Hawkes, C., Howells, L., Howie, L., Humphreys, R., Ishii, H. A., Kataoka, Y., Katayama, I., Kouwenhoven, W., Langan, S. M., Leshem, Y. A., Merhand, S., Mina-Osorio, P., Murota, H., Nakahara, T., Nunes, F. P., Nygaard, U., Nygårdas, M., Ohya, Y., Ono, E., Rehbinder, E., Rogers, N. K., Romeijn, G. L. E., Schuttelaar, M. L. A., Sears, A. V., Simpson, M. A., Singh, J. A., Srour, J., Stuart, B., Svensson, Talmo, G., Talmo, H., Teixeira, H. D., Thyssen, J. P., Todd, G., Torchet, F., Volke, A., von Kobyletzki, L., Weisshaar, E., Wollenberg, A. & Zaniboni, M., May 1 2018, In : British Journal of Dermatology. 178, 5, p. e332-e341

Research output: Contribution to journalArticle

Atopic Dermatitis
Eczema
Quality of Life
Outcome Assessment (Health Care)
Clinical Trials