Eric Orwoll

Professor

  • 24588 Citations
  • 86 h-Index
1976 …2018
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Research Output 1978 2018

2018
Osteoporotic Fractures
Tomography
Bone and Bones
Bone Density
Finite Element Analysis

Dietary patterns and longitudinal change in hip bone mineral density among older men

for the Osteoporotic Fractures in Men (MrOS) Study Research Group, Feb 15 2018, (Accepted/In press) In : Osteoporosis International. p. 1-11 11 p.

Research output: Contribution to journalArticle

Pelvic Bones
Bone Density
Hip
Food
Vegetables
1 Citations

Exome-wide rare variant analyses of two bone mineral density phenotypes: The challenges of analyzing rare genetic variation

Sun, J., Oualkacha, K., Forgetta, V., Zheng, H. F., Richards, J. B., Evans, D. S., Orwoll, E. & Greenwood, C. M. T., Dec 1 2018, In : Scientific Reports. 8, 1, 220

Research output: Contribution to journalArticle

Exome
Bone Density
Phenotype
Osteoporotic Fractures
Genes
2 Citations

Falls Predict Fractures Independently of FRAX Probability: A Meta-Analysis of the Osteoporotic Fractures in Men (MrOS) Study

Harvey, N. C., Odén, A., Orwoll, E., Lapidus, J., Kwok, T., Karlsson, M. K., Rosengren, B. E., Ljunggren, Ö., Cooper, C., McCloskey, E., Kanis, J. A., Ohlsson, C., Mellström, D. & Johansson, H., Mar 1 2018, In : Journal of Bone and Mineral Research. 33, 3, p. 510-516 7 p.

Research output: Contribution to journalArticle

Osteoporotic Fractures
Osteoporosis
Meta-Analysis
Epidemiology
Confidence Intervals
1 Citations

Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men

Eriksson, A. L. , Perry, J. R. B. , Coviello, A. D. , Delgado, G. E. , Ferrucci, L. , Hoffman, A. R. , Huhtaniemi, I. T. , Ikram, M. A. , Karlsson, M. K. , Kleber, M. E. , Laughlin, G. A. , Liu, Y. , Lorentzon, M. , Lunetta, K. L. , Mellström, D. , Murabito, J. M. , Murray, A. , Nethander, M. , Nielson, C. M. , Prokopenko, I. & 20 others Pye, S. R., Raffel, L. J., Rivadeneira, F., Srikanth, P., Stolk, L., Teumer, A., Travison, T. G., Uitterlinden, A. G., Vaidya, D., Vanderschueren, D., Zmuda, J. M., März, W., Orwoll, E. S., Ouyang, P., Vandenput, L., Wu, F. C. W., de Jong, F. H., Bhasin, S., Kiel, D. P. & Ohlsson, C., Mar 1 2018, In : The Journal of clinical endocrinology and metabolism. 103, 3, p. 991-1004 14 p.

Research output: Contribution to journalArticle

Steroid 11-beta-Hydroxylase
Bone Density
Estradiol
Estrogens
X Chromosome

Growth characteristics in individuals with osteogenesis imperfecta in North America: results from a multicenter study

, Members Of The Brittle Bone Disorders Consortium*, Jul 4 2018, (Accepted/In press) In : Genetics in Medicine. p. 1-9 9 p.

Research output: Contribution to journalArticle

Osteogenesis Imperfecta
North America
Multicenter Studies
Growth
Body Mass Index

High-throughput serum proteomics for the identification of protein biomarkers of mortality in older men

Orwoll, E. S., Wiedrick, J., Jacobs, J., Baker, E. S., Piehowski, P., Petyuk, V., Gao, Y., Shi, T., Smith, R. D., Bauer, D. C., Cummings, S. R., Nielson, C. M. & Lapidus, J., Jan 1 2018, (Accepted/In press) In : Aging Cell.

Research output: Contribution to journalArticle

Proteomics
Biomarkers
Mortality
Serum
Proteins
4 Citations

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects

Medina-Gomez, C. , Kemp, J. P. , Trajanoska, K. , Luan, J. , Chesi, A. , Ahluwalia, T. S. , Mook-Kanamori, D. O. , Ham, A. , Hartwig, F. P. , Evans, D. S. , Joro, R. , Nedeljkovic, I. , Zheng, H. F. , Zhu, K. , Atalay, M. , Liu, C. T. , Nethander, M. , Broer, L. , Porleifsson, G. , Mullin, B. H. & 69 others Handelman, S. K., Nalls, M. A., Jessen, L. E., Heppe, D. H. M., Richards, J. B., Wang, C., Chawes, B., Schraut, K. E., Amin, N., Wareham, N., Karasik, D., Van der Velde, N., Ikram, M. A., Zemel, B. S., Zhou, Y., Carlsson, C. J., Liu, Y., McGuigan, F. E., Boer, C. G., Bønnelykke, K., Ralston, S. H., Robbins, J. A., Walsh, J. P., Zillikens, M. C., Langenberg, C., Li-Gao, R., Williams, F. M. K., Harris, T. B., Akesson, K., Jackson, R. D., Sigurdsson, G., den Heijer, M., van der Eerden, B. C. J., van de Peppel, J., Spector, T. D., Pennell, C., Horta, B. L., Felix, J. F., Zhao, J. H., Wilson, S. G., de Mutsert, R., Bisgaard, H., Styrkársdóttir, U., Jaddoe, V. W., Orwoll, E., Lakka, T. A., Scott, R., Grant, S. F. A., Lorentzon, M., van Duijn, C. M., Wilson, J. F., Stefansson, K., Psaty, B. M., Kiel, D. P., Ohlsson, C., Ntzani, E., van Wijnen, A. J., Forgetta, V., Ghanbari, M., Logan, J. G., Williams, G. R., Bassett, J. H. D., Croucher, P. I., Evangelou, E., Uitterlinden, A. G., Ackert-Bicknell, C. L., Tobias, J. H., Evans, D. M. & Rivadeneira, F., Jan 4 2018, In : American Journal of Human Genetics. 102, 1, p. 88-102 15 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bone Density
Meta-Analysis
Osteoporosis
Bone and Bones

Normative Values of Muscle Power Using Force Plate Jump Tests in Men Aged 77–101 Years: The Osteoporotic Fractures in Men (MrOS) Study

Osteoporotic Fractures in Men (MrOS) Research Group, Jul 7 2018, (Accepted/In press) In : Journal of Nutrition, Health and Aging. p. 1-9 9 p.

Research output: Contribution to journalArticle

Osteoporotic Fractures
Muscles
Activities of Daily Living
Age Groups
Independent Living
1 Citations

Osteoporosis and Hip Fracture Risk From Routine Computed Tomography Scans: The Fracture, Osteoporosis, and CT Utilization Study (FOCUS)

Adams, A. L., Fischer, H., Kopperdahl, D. L., Lee, D. C., Black, D. M., Bouxsein, M. L., Fatemi, S., Khosla, S., Orwoll, E. S., Siris, E. S. & Keaveny, T. M., Jan 1 2018, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

Photon Absorptiometry
Hip Fractures
Osteoporosis
Pelvic Bones
Tomography

Phylogenetic placement of exact amplicon sequences improves associations with clinical information

Janssen, S., McDonald, D., Gonzalez, A., Navas-Molina, J. A., Jiang, L., Xu, Z. Z., Winker, K., Kado, D. M., Orwoll, E., Manary, M., Mirarab, S. & Knight, R., May 1 2018, In : mSystems. 3, 3, e00021-18

Research output: Contribution to journalArticle

Reactor startup
Exact Sequence
Phylogenetics
Placement
Fragment
1 Citations

Serum Sclerostin Levels in Adults With Osteogenesis Imperfecta: Comparison With Normal Individuals and Response to Teriparatide Therapy

Nicol, L., Wang, Y., Smith, R., Sloan, J., Nagamani, S. C. S., Shapiro, J., Lee, B. & Orwoll, E., Feb 1 2018, In : Journal of Bone and Mineral Research. 33, 2, p. 307-315 9 p.

Research output: Contribution to journalArticle

Teriparatide
Osteogenesis Imperfecta
Serum
Therapeutics
Bone Density

Serum sodium and cognition in older community-dwelling men

Nowak, K. L., Yaffe, K., Orwoll, E. S., Ix, J. H., You, Z., Barrett-Connor, E., Hoffman, A. R. & Chonchol, M., Mar 7 2018, In : Clinical Journal of the American Society of Nephrology. 13, 3, p. 366-374 9 p.

Research output: Contribution to journalArticle

Trail Making Test
Independent Living
Osteoporotic Fractures
Hyponatremia
Cognition

The epidemiology of wrist fractures in older men: the Osteoporotic Fractures in Men (MrOS) study

for the Osteoporotic Fractures in Men (MrOS) Study Research Group, Jan 17 2018, (Accepted/In press) In : Osteoporosis International. p. 1-12 12 p.

Research output: Contribution to journalArticle

Osteoporotic Fractures
Wrist
Epidemiology
Osteoporosis
Independent Living

The importance of the circadian system & sleep for bone health

Swanson, C. M., Kohrt, W. M., Buxton, O. M., Everson, C. A., Wright, K. P., Orwoll, E. S. & Shea, S. A., Jan 1 2018, (Accepted/In press) In : Metabolism: Clinical and Experimental.

Research output: Contribution to journalArticle

Sleep
Bone and Bones
Health
Biological Phenomena
Circadian Clocks
1 Citations

Volumetric Bone Mineral Density and Failure Load of Distal Limbs Predict Incident Clinical Fracture Independent HR-pQCT BMD and Failure Load Predicts Incident Clinical Fracture of FRAX and Clinical Risk Factors Among Older Men

Langsetmo, L., Peters, K. W., Burghardt, A. J., Ensrud, K. E., Fink, H. A., Cawthon, P. M., Cauley, J. A., Schousboe, J. T., Barrett-Connor, E. & Orwoll, E. S., Jan 1 2018, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

Osteoporotic Fractures
Bone Density
Extremities
Tomography
Tibia

Weight loss in men in late life and bone strength and microarchitecture: a prospective study

for the Osteoporotic Fractures in Men (MrOS) Research Group, Mar 23 2018, (Accepted/In press) In : Osteoporosis International. p. 1-10 10 p.

Research output: Contribution to journalArticle

Weight Loss
Prospective Studies
Bone and Bones
Weights and Measures
Weight Gain
2017
2 Citations

24-hour profile of serum sclerostin and its association with bone biomarkers in men

Swanson, C., Shea, S. A., Wolfe, P., Markwardt, S., Cain, S. W., Munch, M., Czeisler, C. A., Orwoll, E. S. & Buxton, O. M., Jul 26 2017, (Accepted/In press) In : Osteoporosis International. p. 1-9 9 p.

Research output: Contribution to journalArticle

Osteocytes
Periodicity
Bone Remodeling
Biomarkers
Bone and Bones
1 Citations

Association of incident hip fracture with the estimated femoral strength by finite element analysis of DXA scans in the Osteoporotic Fractures in Men (MrOS) study

for the Osteoporotic Fractures in Men (MrOS) Study Research Group, Nov 22 2017, (Accepted/In press) In : Osteoporosis International. p. 1-9 9 p.

Research output: Contribution to journalArticle

Finite Element Analysis
Osteoporotic Fractures
Photon Absorptiometry
Hip Fractures
Thigh
2 Citations

Association of Increased Urinary Albumin With Risk of Incident Clinical Fracture and Rate of Hip Bone Loss: The Osteoporotic Fractures in Men Study

Fink, H. A., Vo, T. N., Langsetmo, L., Barzilay, J. I., Cauley, J. A., Schousboe, J. T., Orwoll, E. S., Canales, M. T., Ishani, A., Lane, N. E. & Ensrud, K. E., 2017, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

Pelvic Bones
Osteoporotic Fractures
Albumins
Albuminuria
Creatinine
5 Citations

Association of Trabecular Bone Score (TBS) With Incident Clinical and Radiographic Vertebral Fractures Adjusted for Lumbar Spine BMD in Older Men: A Prospective Cohort Study

Schousboe, J. T., Vo, T. N., Langsetmo, L., Taylor, B. C., Cawthon, P. M., Schwartz, A. V., Bauer, D. C., Orwoll, E. S., Lane, N. E., Barrett-Connor, E. & Ensrud, K. E., 2017, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

Spine
Cohort Studies
Prospective Studies
Body Mass Index
Confidence Intervals
5 Citations

Bone Turnover Markers After Sleep Restriction and Circadian Disruption: A Mechanism for Sleep-Related Bone Loss in Humans

Swanson, C. M., Shea, S. A., Wolfe, P., Cain, S. W., Munch, M., Vujovic, N., Czeisler, C. A., Buxton, O. M. & Orwoll, E. S., Oct 1 2017, In : The Journal of clinical endocrinology and metabolism. 102, 10, p. 3722-3730 9 p.

Research output: Contribution to journalArticle

Bone Remodeling
Sleep
Bone
Bone and Bones
Biomarkers
1 Citations

Clinical Definitions of Sarcopenia and Risk of Hospitalization in Community-Dwelling Older Men: The Osteoporotic Fractures in Men Study

Cawthon, P. M., Lui, L. Y., Taylor, B. C., McCulloch, C. E., Cauley, J. A., Lapidus, J., Orwoll, E. & Ensrud, K. E., Oct 1 2017, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 72, 10, p. 1383-1389 7 p.

Research output: Contribution to journalArticle

Sarcopenia
Independent Living
Osteoporotic Fractures
Hospitalization
Inpatients

Clinical practice guidelines for osteoporosis: Translating data to patients?

Orwoll, E. S., Jun 6 2017, In : Annals of Internal Medicine. 166, 11, p. 852-853 2 p.

Research output: Contribution to journalEditorial

Practice Guidelines
Osteoporosis
7 Citations

Comparing identified and statistically significant lipids and polar metabolites in 15-year old serum and dried blood spot samples for longitudinal studies

Kyle, J. E., Casey, C. P., Stratton, K. G., Zink, E. M., Kim, Y. M., Zheng, X., Monroe, M. E., Weitz, K. K., Bloodsworth, K. J., Orton, D. J., Ibrahim, Y. M., Moore, R. J., Lee, C. G., Pedersen, C., Orwoll, E., Smith, R. D., Burnum-Johnson, K. E. & Baker, E. S., Mar 15 2017, In : Rapid Communications in Mass Spectrometry. 31, 5, p. 447-456 10 p.

Research output: Contribution to journalArticle

Metabolites
Blood
Lipids
Liquid chromatography
HDL Lipoproteins
1 Citations

Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study

for the Osteoporotic Fractures in Men (MrOS) Study Group, Dec 1 2017, In : Archives of Osteoporosis. 12, 1, 91

Research output: Contribution to journalArticle

Bone Density
Hip
Spine
Femur Neck
Area Under Curve

Correction to: Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study (Arch Osteoporos, 10.1007/s11657-017-0389-1)

for the Osteoporotic Fractures in Men (MrOS) Study Group, Dec 1 2017, In : Archives of Osteoporosis. 12, 1, 99

Research output: Contribution to journalComment/debate

Manuscripts
Hip
Spine
2 Citations

Cystatin C and the Risk of Frailty and Mortality in Older Men

Hart, A., Blackwell, T. L., Paudel, M. L., Taylor, B. C., Orwoll, E. S., Cawthon, P. M. & Ensrud, K. E., Jul 1 2017, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 72, 7, p. 965-970 6 p.

Research output: Contribution to journalArticle

Cystatin C
Mortality
Creatinine
Glomerular Filtration Rate
Confidence Intervals

DXA-derived hip shape is related to osteoarthritis: Findings from in the MrOS cohort

Faber, B. G., Baird, D., Gregson, C. L., Gregory, J. S., Barr, R. J., Aspden, R. M., Lynch, J., Nevitt, M. C., Lane, N. E., Orwoll, E. & Tobias, J. H., 2017, (Accepted/In press) In : Osteoarthritis and Cartilage.

Research output: Contribution to journalArticle

Cams
Photon Absorptiometry
Osteoarthritis
Hip
X rays
2 Citations

Evaluating Atypical Features of Femur Fractures: How Change in Radiological Criteria Influenced Incidence and Demography of Atypical Femur Fractures in a Community Setting

LeBlanc, E. S., Rosales, A. G., Black, D. M., Genant, H. K., Dell, R. M., Friess, D. M., Boardman, D. L., Bauer, D. C., de Papp, A., Santora, A. C. & Orwoll, E. S., Nov 1 2017, In : Journal of Bone and Mineral Research. 32, 11, p. 2304-2314 11 p.

Research output: Contribution to journalArticle

Femoral Fractures
Femur
Demography
Incidence
Minerals
1 Citations

Further elucidation of the potential benefits of testosterone therapy in older men

Orwoll, E. Apr 1 2017 In : JAMA Internal Medicine. 177, 4, p. 459-460 2 p.

Research output: Contribution to journalEditorial

Testosterone
Therapeutics
9 Citations

Genetic variants associated with circulating parathyroid hormone

Robinson-Cohen, C. , Lutsey, P. L. , Kleber, M. E. , Nielson, C. M. , Mitchell, B. D. , Bis, J. C. , Eny, K. M. , Portas, L. , Eriksson, J. , Lorentzon, M. , Koller, D. L. , Milaneschi, Y. , Teumer, A. , Pilz, S. , Nethander, M. , Selvin, E. , Tang, W. , Weng, L. C. , Wong, H. S. , Lai, D. & 29 others Peacock, M., Hannemann, A., Völker, U., Homuth, G., Nauk, M., Murgia, F., Pattee, J. W., Orwoll, E., Zmuda, J. M., Riancho, J. A., Wolf, M., Williams, F., Penninx, B., Econs, M. J., Ryan, K. A., Ohlsson, C., Paterson, A. D., Psaty, B. M., Siscovick, D. S., Rotter, J. I., Pirastu, M., Streeten, E., März, W., Fox, C., Coresh, J., Wallaschofski, H., Pankow, J. S., De Boer, I. H. & Kestenbaum, B., May 1 2017, In : Journal of the American Society of Nephrology. 28, 5, p. 1553-1565 13 p.

Research output: Contribution to journalArticle

Parathyroid Hormone
Single Nucleotide Polymorphism
Serum
Secondary Hyperparathyroidism
Dihydroxycholecalciferols
22 Citations

Harmonized reference ranges for circulating testosterone levels in men of four cohort studies in the United States and Europe

Travison, T. G., Vesper, H. W., Orwoll, E., Wu, F., Kaufman, J. M., Wang, Y., Lapauw, B., Fiers, T., Matsumoto, A. M. & Bhasin, S., Apr 1 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 4, p. 1161-1173 13 p.

Research output: Contribution to journalArticle

Testosterone
Reference Values
Cohort Studies
Disease control
Assays
1 Citations

High dairy protein intake is associated with greater bone strength parameters at the distal radius and tibia in older men: a cross-sectional study

for the Osteoporotic Fractures in Men (MrOS) Study Research Group, Oct 23 2017, (Accepted/In press) In : Osteoporosis International. p. 1-9 9 p.

Research output: Contribution to journalArticle

Tibia
Cross-Sectional Studies
Bone and Bones
Proteins
Energy Intake
3 Citations

Identification of Hip BMD Loss and Fracture Risk Markers Through Population-Based Serum Proteomics

Nielson, C. M., Wiedrick, J., Shen, J., Jacobs, J., Baker, E. S., Baraff, A., Piehowski, P., Lee, C. G., Baratt, A., Petyuk, V., Mcweeney, S., Lim, J. Y., Bauer, D. C., Lane, N. E., Cawthon, P. M., Smith, R. D., Lapidus, J. & Orwoll, E. S., 2017, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

Pelvic Bones
Proteomics
Bone Density
Hip Fractures
Serum
10 Citations

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

Zillikens, M. C. , Demissie, S. , Hsu, Y. H. , Yerges-Armstrong, L. M. , Chou, W. C. , Stolk, L. , Livshits, G. , Broer, L. , Johnson, T. , Koller, D. L. , Kutalik, Z. , Luan, JA. , Malkin, I. , Ried, J. S. , Smith, A. V. , Thorleifsson, G. , Vandenput, L. , Hua Zhao, J. , Zhang, W. , Aghdassi, A. & 173 others Åkesson, K., Amin, N., Baier, L. J., Barroso, I., Bennett, D. A., Bertram, L., Biffar, R., Bochud, M., Boehnke, M., Borecki, I. B., Buchman, A. S., Byberg, L., Campbell, H., Campos Obanda, N., Cauley, J. A., Cawthon, P. M., Cederberg, H., Chen, Z., Cho, N. H., Jin Choi, H., Claussnitzer, M., Collins, F., Cummings, S. R., De Jager, P. L., Demuth, I., Dhonukshe-Rutten, R. A. M., DIatchenko, L., Eiriksdottir, G., Enneman, A. W., Erdos, M., Eriksson, J. G., Eriksson, J., Estrada, K., Evans, D. S., Feitosa, M. F., Fu, M., Garcia, M., Gieger, C., Girke, T., Glazer, N. L., Grallert, H., Grewal, J., Han, B. G., Hanson, R. L., Hayward, C., Hofman, A., Hoffman, E. P., Homuth, G., Hsueh, W. C., Hubal, M. J., Hubbard, A., Huffman, K. M., Husted, L. B., Illig, T., Ingelsson, E., Ittermann, T., Jansson, J. O., Jordan, J. M., Jula, A., Karlsson, M., Khaw, K. T., Kilpelaïnen, T. O., Klopp, N., Kloth, J. S. L., Koistinen, H. A., Kraus, W. E., Kritchevsky, S., Kuulasmaa, T., Kuusisto, J., Laakso, M., Lahti, J., Lang, T., Langdahl, B. L., Launer, L. J., Lee, J. Y., Lerch, M. M., Lewis, J. R., Lind, L., Lindgren, C., Liu, Y., Liu, T., Liu, Y., Ljunggren, Ö., Lorentzon, M., Luben, R. N., Maixner, W., McGuigan, F. E., Medina-Gomez, C., Meitinger, T., Melhus, H., Mellström, D., Melov, S., Michaëlsson, K., Mitchell, B. D., Morris, A. P., Mosekilde, L., Newman, A., Nielson, C. M., O'Connell, J. R., Oostra, B. A., Orwoll, E. S., Palotie, A., Parker, S., Peacock, M., Perola, M., Peters, A., Polasek, O., Prince, R. L., Raïkkönen, K., Ralston, S. H., Ripatti, S., Robbins, J. A., Rotter, J. I., Rudan, I., Salomaa, V., Satterfield, S., Schadt, E. E., Schipf, S., Scott, L., Sehmi, J., Shen, J., Soo Shin, C., Sigurdsson, G., Smith, S., Soranzo, N., Stančáková, A., Steinhagen-Thiessen, E., Streeten, E. A., Styrkarsdottir, U., Swart, K. M. A., Tan, S. T., Tarnopolsky, M. A., Thompson, P., Thomson, C. A., Thorsteinsdottir, U., Tikkanen, E., Tranah, G. J., Tuomilehto, J., Van Schoor, N. M., Verma, A., Vollenweider, P., Völzke, H., Wactawski-Wende, J., Walker, M., Weedon, M. N., Welch, R., Wichman, H. E., Widen, E., Williams, F. M. K., Wilson, J. F., Wright, N. C., Xie, W., Yu, L., Zhou, Y., Chambers, J. C., Döring, A., Van Duijn, C. M., Econs, M. J., Gudnason, V., Kooner, J. S., Psaty, B. M., Spector, T. D., Stefansson, K., Rivadeneira, F., Uitterlinden, A. G., Wareham, N. J., Ossowski, V., Waterworth, D., Loos, R. J. F., Karasik, D., Harris, T. B., Ohlsson, C. & Kiel, D. P., Dec 1 2017, In : Nature Communications. 8, 1, 80

Research output: Contribution to journalArticle

genome
Genome-Wide Association Study
loci
Polymorphism
Single Nucleotide Polymorphism
13 Citations

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

GEFOS Anytype of Fracture Consortium, Jul 12 2017, In : Nature Communications. 8, 16015

Research output: Contribution to journalArticle

Signal transduction
fitness
Genome-Wide Association Study
Hand Strength
loci
13 Citations

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis

Manousaki, D. , Dudding, T. , Haworth, S. , Hsu, Y. H. , Liu, C. T. , Medina-Gómez, C. , Voortman, T. , van der Velde, N. , Melhus, H. , Robinson-Cohen, C. , Cousminer, D. L. , Nethander, M. , Vandenput, L. , Noordam, R. , Forgetta, V. , Greenwood, C. M. T. , Biggs, M. L. , Psaty, B. M. , Rotter, J. I. , Zemel, B. S. & 33 others Mitchell, J. A., Taylor, B., Lorentzon, M., Karlsson, M., Jaddoe, V. V. W., Tiemeier, H., Campos-Obando, N., Franco, O. H., Utterlinden, A. G., Broer, L., van Schoor, N. M., Ham, A. C., Ikram, M. A., Karasik, D., de Mutsert, R., Rosendaal, F. R., den Heijer, M., Wang, T. J., Lind, L., Orwoll, E. S., Mook-Kanamori, D. O., Michaëlsson, K., Kestenbaum, B., Ohlsson, C., Mellström, D., de Groot, L. C. P. G. M., Grant, S. F. A., Kiel, D. P., Zillikens, M. C., Rivadeneira, F., Sawcer, S., Timpson, N. J. & Richards, J. B., Aug 3 2017, In : American Journal of Human Genetics. 101, 2, p. 227-238 12 p.

Research output: Contribution to journalArticle

Vitamin D
Multiple Sclerosis
Odds Ratio
Genome
Confidence Intervals
4 Citations

Low Testosterone, but Not Estradiol, Is Associated With Incident Falls in Older Men: The International MrOS Study

Vandenput, L., Mellström, D., Laughlin, G. A., Cawthon, P. M., Cauley, J. A., Hoffman, A. R., Karlsson, M. K., Rosengren, B. E., Ljunggren, Ö., Nethander, M., Eriksson, A. L., Lorentzon, M., Leung, J., Kwok, T., Orwoll, E. S. & Ohlsson, C., 2017, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

Testosterone
Hong Kong
Estradiol
Odds Ratio
Sweden
1 Citations

NFAT5 and SLC4A10 loci associate with plasma osmolality

Böger, C. A. , Gorski, M. , McMahon, G. M. , Xu, H. , Chang, Y. P. C. , Van Der Most, P. J. , Navis, G. , Nolte, I. M. , De Borst, M. H. , Zhang, W. , Lehne, B. , Loh, M. , Tan, S. T. , Boerwinkle, E. , Grams, M. E. , Sekula, P. , Li, M. , Wilmot, B. , Moon, J. G. , Scheet, P. & 86 others Cucca, F., Xiao, X., Lyytikäinen, L. P., Delgado, G., Grammer, T. B., Kleber, M. E., Sedaghat, S., Rivadeneira, F., Corre, T., Kutalik, Z., Bergmann, S., Nielson, C. M., Srikanth, P., Teumer, A., Müller-Nurasyid, M., Brockhaus, A. C., Pfeufer, A., Rathmann, W., Peters, A., Matsumoto, M., De Andrade, M., Atkinson, E. J., Robinson-Cohen, C., De Boer, I. H., Hwang, S. J., Heid, I. M., Gögele, M., Concas, M. P., Tanaka, T., Bandinelli, S., Nalls, M. A., Singleton, A., Tajuddin, S. M., Adeyemo, A., Zhou, J., Doumatey, A., McWeeney, S., Murabito, J., Franceschini, N., Flessner, M., Shlipak, M., Wilson, J. G., Chen, G., Rotimi, C. N., Zonderman, A. B., Evans, M. K., Ferrucci, L., Devuyst, O., Pirastu, M., Shuldiner, A., Hicks, A. A., Pramstaller, P. P., Kestenbaum, B., Kardia, S. L. R., Turner, S. T., Study, L. C., Briske, T. E., Gieger, C., Strauch, K., Meisinger, C., Meitinger, T., Völker, U., Nauck, M., Völzke, H., Vollenweider, P., Bochud, M., Waeber, G., Kähönen, M., Lehtimäki, T., März, W., Dehghan, A., Franco, O. H., Uitterlinden, A. G., Hofman, A., Taylor, H. A., Chambers, J. C., Kooner, J. S., Fox, C. S., Hitzemann, R., Orwoll, E. S., Pattaro, C., Schlessinger, D., Köttgen, A., Snieder, H., Parsa, A. & Cohen, D. M., Aug 1 2017, In : Journal of the American Society of Nephrology. 28, 8, p. 2311-2321 11 p.

Research output: Contribution to journalArticle

Osmolar Concentration
Meta-Analysis
Water
Sodium
Hypernatremia
1 Citations

Obesity and Falls in a Prospective Study of Older Men: The Osteoporotic Fractures in Men Study

Hooker, E. R., Shrestha, S., Lee, C. G., Cawthon, P. M., Abrahamson, M., Ensrud, K., Stefanick, M. L., Dam, T. T., Marshall, L. M., Orwoll, E. S. & Nielson, C. M., Oct 1 2017, In : Journal of Aging and Health. 29, 7, p. 1235-1250 16 p.

Research output: Contribution to journalArticle

Osteoporotic Fractures
Obesity
Prospective Studies
Body Mass Index
Confidence Intervals
1 Citations

Older men with anemia have increased fracture risk independent of bone mineral density

Valderrábano, R. J., Lee, J., Lui, L. Y., Hoffman, A. R., Cummings, S. R., Orwoll, E. S. & Wu, J. Y., Jul 1 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 7, p. 2199-2206 8 p.

Research output: Contribution to journalArticle

Bone Density
Minerals
Anemia
Bone
Confidence Intervals

Rest-activity circadian rhythms and bone mineral density in elderly men

for the Osteoporotic Fractures in Men (MrOS) Study Research Group, Dec 1 2017, In : Bone Reports. 7, p. 156-163 8 p.

Research output: Contribution to journalArticle

Circadian Rhythm
Bone Density
Femur Neck
Sleep
Social Adjustment
2 Citations

Screening for Osteoporosis in Older Men: Operating Characteristics of Proposed Strategies for Selecting Men for BMD Testing

The Osteoporotic Fractures In Men Research Group, Aug 16 2017, (Accepted/In press) In : Journal of General Internal Medicine. p. 1-7 7 p.

Research output: Contribution to journalArticle

Bone Density
Osteoporosis
Area Under Curve
Femur Neck
Sensitivity and Specificity
2 Citations

Successful collection of stool samples for microbiome analyses from a large community-based population of elderly men

Abrahamson, M., Hooker, E., Ajami, N. J., Petrosino, J. F. & Orwoll, E. S., Sep 1 2017, In : Contemporary Clinical Trials Communications. 7, p. 158-162 5 p.

Research output: Contribution to journalArticle

Microbiota
Population
Independent Living
DNA
Postal Service
5 Citations

The Association Between Protein Intake by Source and Osteoporotic Fracture in Older Men: A Prospective Cohort Study

Langsetmo, L., Shikany, J. M., Cawthon, P. M., Cauley, J. A., Taylor, B. C., Vo, T. N., Bauer, D. C., Orwoll, E. S., Schousboe, J. T. & Ensrud, K. E., 2017, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

Osteoporotic Fractures
Cohort Studies
Prospective Studies
Energy Intake
Confidence Intervals
1 Citations

Trajectories of the relationships of physical activity with body composition changes in older men: the MrOS study

Laddu, D. R., Cawthon, P. M., Parimi, N., Hoffman, A. R., Orwoll, E., Miljkovic, I. & Stefanick, M. L., Jun 5 2017, In : BMC Geriatrics. 17, 1, 119

Research output: Contribution to journalArticle

Body Composition
Exercise
Fats
Independent Living
Weights and Measures
4 Citations

Vertebral Fracture Risk in Diabetic Elderly Men: The MrOS Study

Napoli, N., Schwartz, A. V., Schafer, A. L., Vittinghoff, E., Cawthon, P. M., Parimi, N., Orwoll, E., Strotmeyer, E. S., Hoffman, A. R., Barrett-Connor, E. & Black, D. M., Jan 1 2017, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

Bone Density
Spine
Osteoporotic Fractures
Incidence
Photon Absorptiometry
2016
11 Citations

Actigraphy- and Polysomnography-Measured Sleep Disturbances, Inflammation, and Mortality Among Older Men

for the Osteoporotic Fractures in Men (MrOS) Research Group, Feb 18 2016, (Accepted/In press) In : Psychosomatic Medicine.

Research output: Contribution to journalArticle

Actigraphy
Polysomnography
Sleep
Inflammation
Mortality
3 Citations

Areal and volumetric bone mineral density and risk of multiple types of fracture in older men

Chalhoub, D., Orwoll, E. S., Cawthon, P. M., Ensrud, K. E., Boudreau, R., Greenspan, S., Newman, A. B., Zmuda, J., Bauer, D., Cummings, S. & Cauley, J. A., Nov 1 2016, In : Bone. 92, p. 100-106 7 p.

Research output: Contribution to journalArticle

Bone Density
Femur Neck
Spine
Sternum
Ribs