Research Output 1978 2017

2017

24-hour profile of serum sclerostin and its association with bone biomarkers in men

Swanson, C., Shea, S. A., Wolfe, P., Markwardt, S., Cain, S. W., Munch, M., Czeisler, C. A., Orwoll, E. S. & Buxton, O. M. Jul 26 2017 (Accepted/In press) In : Osteoporosis International. p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Osteocytes
Biomarkers
Bone and Bones
Serum
Periodicity

Association of Increased Urinary Albumin With Risk of Incident Clinical Fracture and Rate of Hip Bone Loss: The Osteoporotic Fractures in Men Study

Fink, H. A., Vo, T. N., Langsetmo, L., Barzilay, J. I., Cauley, J. A., Schousboe, J. T., Orwoll, E. S., Canales, M. T., Ishani, A., Lane, N. E. & Ensrud, K. E. 2017 (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Research - peer-reviewArticle

Pelvic Bones
Osteoporotic Fractures
Albumins
Creatinine
Albuminuria
1 Citations

Association of Trabecular Bone Score (TBS) With Incident Clinical and Radiographic Vertebral Fractures Adjusted for Lumbar Spine BMD in Older Men: A Prospective Cohort Study

Schousboe, J. T., Vo, T. N., Langsetmo, L., Taylor, B. C., Cawthon, P. M., Schwartz, A. V., Bauer, D. C., Orwoll, E. S., Lane, N. E., Barrett-Connor, E. & Ensrud, K. E. 2017 (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Research - peer-reviewArticle

Spine
Cohort Studies
Prospective Studies
Cancellous Bone
Body Mass Index
1 Citations

Bone Turnover Markers After Sleep Restriction and Circadian Disruption: A Mechanism for Sleep-Related Bone Loss in Humans

Swanson, C. M., Shea, S. A., Wolfe, P., Cain, S. W., Munch, M., Vujovic, N., Czeisler, C. A., Buxton, O. M. & Orwoll, E. S. Oct 1 2017 In : The Journal of clinical endocrinology and metabolism. 102, 10, p. 3722-3730 9 p.

Research output: Research - peer-reviewArticle

Bone Remodeling
Sleep
Bone and Bones
Bone
Biomarkers

Clinical Definitions of Sarcopenia and Risk of Hospitalization in Community-Dwelling Older Men: The Osteoporotic Fractures in Men Study

Cawthon, P. M., Lui, L. Y., Taylor, B. C., McCulloch, C. E., Cauley, J. A., Lapidus, J., Orwoll, E. & Ensrud, K. E. Oct 1 2017 In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 72, 10, p. 1383-1389 7 p.

Research output: Research - peer-reviewArticle

Sarcopenia
Independent Living
Osteoporotic Fractures
Hospitalization
Inpatients

Clinical practice guidelines for osteoporosis: Translating data to patients?

Orwoll, E. S. Jun 6 2017 In : Annals of Internal Medicine. 166, 11, p. 852-853 2 p.

Research output: Research - peer-reviewEditorial

Comparing identified and statistically significant lipids and polar metabolites in 15-year old serum and dried blood spot samples for longitudinal studies

Kyle, J. E., Casey, C. P., Stratton, K. G., Zink, E. M., Kim, Y. M., Zheng, X., Monroe, M. E., Weitz, K. K., Bloodsworth, K. J., Orton, D. J., Ibrahim, Y. M., Moore, R. J., Lee, C. G., Pedersen, C., Orwoll, E., Smith, R. D., Burnum-Johnson, K. E. & Baker, E. S. Mar 15 2017 In : Rapid Communications in Mass Spectrometry. 31, 5, p. 447-456 10 p.

Research output: Research - peer-reviewArticle

Metabolites
Blood
Lipids
Liquid chromatography
Temperature

Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study

Gourlay, M. L., Ritter, V. S., Fine, J. P., Overman, R. A., Schousboe, J. T., Cawthon, P. M., Orwoll, E. S., Nguyen, T. V., Lane, N. E., Cummings, S. R., Kado, D. M., Lapidus, J. A., Diem, S. J., Ensrud, K. E. & for the Osteoporotic Fractures in Men (MrOS) Study Group Dec 1 2017 In : Archives of Osteoporosis. 12, 1, 91

Research output: Research - peer-reviewArticle

Bone Density
Hip
Spine
Femur Neck
Area Under Curve

Correction to: Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study (Arch Osteoporos, 10.1007/s11657-017-0389-1)

Gourlay, M. L., Ritter, V. S., Fine, J. P., Overman, R. A., Schousboe, J. T., Cawthon, P. M., Orwoll, E. S., Nguyen, T. V., Lane, N. E., Cummings, S. R., Kado, D. M., Lapidus, J. A., Diem, S. J., Ensrud, K. E. & for the Osteoporotic Fractures in Men (MrOS) Study Group Dec 1 2017 In : Archives of Osteoporosis. 12, 1, 99

Research output: Research - peer-reviewComment/debate

Manuscripts
Hip
Spine

Cystatin C and the Risk of Frailty and Mortality in Older Men

Hart, A., Blackwell, T. L., Paudel, M. L., Taylor, B. C., Orwoll, E. S., Cawthon, P. M. & Ensrud, K. E. Jul 1 2017 In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 72, 7, p. 965-970 6 p.

Research output: Research - peer-reviewArticle

Cystatin C
Mortality
Creatinine
Glomerular Filtration Rate
Confidence Intervals

DXA-derived hip shape is related to osteoarthritis: Findings from in the MrOS cohort

Faber, B. G., Baird, D., Gregson, C. L., Gregory, J. S., Barr, R. J., Aspden, R. M., Lynch, J., Nevitt, M. C., Lane, N. E., Orwoll, E. & Tobias, J. H. 2017 (Accepted/In press) In : Osteoarthritis and Cartilage.

Research output: Research - peer-reviewArticle

Photon Absorptiometry
Osteoarthritis
Hip
Cams
X rays

Evaluating Atypical Features of Femur Fractures: How Change in Radiological Criteria Influenced Incidence and Demography of Atypical Femur Fractures in a Community Setting

LeBlanc, E. S., Rosales, A. G., Black, D. M., Genant, H. K., Dell, R. M., Friess, D. M., Boardman, D. L., Bauer, D. C., de Papp, A., Santora, A. C. & Orwoll, E. S. Nov 1 2017 In : Journal of Bone and Mineral Research. 32, 11, p. 2304-2314 11 p.

Research output: Research - peer-reviewArticle

Femoral Fractures
Femur
Demography
Incidence
Minerals
1 Citations

Further elucidation of the potential benefits of testosterone therapy in older men

Orwoll, E. Apr 1 2017 In : JAMA Internal Medicine. 177, 4, p. 459-460 2 p.

Research output: Research - peer-reviewEditorial

Genetic variants associated with circulating parathyroid hormone

Robinson-Cohen, C. , Lutsey, P. L. , Kleber, M. E. , Nielson, C. M. , Mitchell, B. D. , Bis, J. C. , Eny, K. M. , Portas, L. , Eriksson, J. , Lorentzon, M. , Koller, D. L. , Milaneschi, Y. , Teumer, A. , Pilz, S. , Nethander, M. , Selvin, E. , Tang, W. , Weng, L. C. , Wong, H. S. , Lai, D. & 29 others Peacock, M., Hannemann, A., Völker, U., Homuth, G., Nauk, M., Murgia, F., Pattee, J. W., Orwoll, E., Zmuda, J. M., Riancho, J. A., Wolf, M., Williams, F., Penninx, B., Econs, M. J., Ryan, K. A., Ohlsson, C., Paterson, A. D., Psaty, B. M., Siscovick, D. S., Rotter, J. I., Pirastu, M., Streeten, E., März, W., Fox, C., Coresh, J., Wallaschofski, H., Pankow, J. S., De Boer, I. H. & Kestenbaum, B. May 1 2017 In : Journal of the American Society of Nephrology. 28, 5, p. 1553-1565 13 p.

Research output: Research - peer-reviewArticle

Parathyroid Hormone
Single Nucleotide Polymorphism
Serum
Genes
Secondary Hyperparathyroidism
3 Citations

Harmonized reference ranges for circulating testosterone levels in men of four cohort studies in the United States and Europe

Travison, T. G., Vesper, H. W., Orwoll, E., Wu, F., Kaufman, J. M., Wang, Y., Lapauw, B., Fiers, T., Matsumoto, A. M. & Bhasin, S. Apr 1 2017 In : Journal of Clinical Endocrinology and Metabolism. 102, 4, p. 1161-1173 13 p.

Research output: Research - peer-reviewArticle

Testosterone
Reference Values
Cohort Studies
Assays
Disease control

High dairy protein intake is associated with greater bone strength parameters at the distal radius and tibia in older men: a cross-sectional study

Langsetmo, L., Shikany, J. M., Burghardt, A. J., Cawthon, P. M., Orwoll, E. S., Cauley, J. A., Taylor, B. C., Schousboe, J. T., Bauer, D. C., Vo, T. N., Ensrud, K. E. & for the Osteoporotic Fractures in Men (MrOS) Study Research Group Oct 23 2017 (Accepted/In press) In : Osteoporosis International. p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Tibia
Cross-Sectional Studies
Bone and Bones
Proteins
Energy Intake
1 Citations

Identification of Hip BMD Loss and Fracture Risk Markers Through Population-Based Serum Proteomics

Nielson, C. M., Wiedrick, J., Shen, J., Jacobs, J., Baker, E. S., Baraff, A., Piehowski, P., Lee, C. G., Baratt, A., Petyuk, V., Mcweeney, S., Lim, J. Y., Bauer, D. C., Lane, N. E., Cawthon, P. M., Smith, R. D., Lapidus, J. & Orwoll, E. S. 2017 (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Research - peer-reviewArticle

Pelvic Bones
Proteomics
Bone Density
Serum
Population
2 Citations

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

Zillikens, M. C. , Demissie, S. , Hsu, Y. H. , Yerges-Armstrong, L. M. , Chou, W. C. , Stolk, L. , Livshits, G. , Broer, L. , Johnson, T. , Koller, D. L. , Kutalik, Z. , Luan, J. A. , Malkin, I. , Ried, J. S. , Smith, A. V. , Thorleifsson, G. , Vandenput, L. , Hua Zhao, J. , Zhang, W. , Aghdassi, A. & 173 others Åkesson, K., Amin, N., Baier, L. J., Barroso, I., Bennett, D. A., Bertram, L., Biffar, R., Bochud, M., Boehnke, M., Borecki, I. B., Buchman, A. S., Byberg, L., Campbell, H., Campos Obanda, N., Cauley, J. A., Cawthon, P. M., Cederberg, H., Chen, Z., Cho, N. H., Jin Choi, H., Claussnitzer, M., Collins, F., Cummings, S. R., De Jager, P. L., Demuth, I., Dhonukshe-Rutten, R. A. M., DIatchenko, L., Eiriksdottir, G., Enneman, A. W., Erdos, M., Eriksson, J. G., Eriksson, J., Estrada, K., Evans, D. S., Feitosa, M. F., Fu, M., Garcia, M., Gieger, C., Girke, T., Glazer, N. L., Grallert, H., Grewal, J., Han, B. G., Hanson, R. L., Hayward, C., Hofman, A., Hoffman, E. P., Homuth, G., Hsueh, W. C., Hubal, M. J., Hubbard, A., Huffman, K. M., Husted, L. B., Illig, T., Ingelsson, E., Ittermann, T., Jansson, J. O., Jordan, J. M., Jula, A., Karlsson, M., Khaw, K. T., Kilpelaïnen, T. O., Klopp, N., Kloth, J. S. L., Koistinen, H. A., Kraus, W. E., Kritchevsky, S., Kuulasmaa, T., Kuusisto, J., Laakso, M., Lahti, J., Lang, T., Langdahl, B. L., Launer, L. J., Lee, J. Y., Lerch, M. M., Lewis, J. R., Lind, L., Lindgren, C., Liu, Y., Liu, T., Liu, Y., Ljunggren, Ö., Lorentzon, M., Luben, R. N., Maixner, W., McGuigan, F. E., Medina-Gomez, C., Meitinger, T., Melhus, H., Mellström, D., Melov, S., Michaëlsson, K., Mitchell, B. D., Morris, A. P., Mosekilde, L., Newman, A., Nielson, C. M., O'Connell, J. R., Oostra, B. A., Orwoll, E. S., Palotie, A., Parker, S., Peacock, M., Perola, M., Peters, A., Polasek, O., Prince, R. L., Raïkkönen, K., Ralston, S. H., Ripatti, S., Robbins, J. A., Rotter, J. I., Rudan, I., Salomaa, V., Satterfield, S., Schadt, E. E., Schipf, S., Scott, L., Sehmi, J., Shen, J., Soo Shin, C., Sigurdsson, G., Smith, S., Soranzo, N., Stančáková, A., Steinhagen-Thiessen, E., Streeten, E. A., Styrkarsdottir, U., Swart, K. M. A., Tan, S. T., Tarnopolsky, M. A., Thompson, P., Thomson, C. A., Thorsteinsdottir, U., Tikkanen, E., Tranah, G. J., Tuomilehto, J., Van Schoor, N. M., Verma, A., Vollenweider, P., Völzke, H., Wactawski-Wende, J., Walker, M., Weedon, M. N., Welch, R., Wichman, H. E., Widen, E., Williams, F. M. K., Wilson, J. F., Wright, N. C., Xie, W., Yu, L., Zhou, Y., Chambers, J. C., Döring, A., Van Duijn, C. M., Econs, M. J., Gudnason, V., Kooner, J. S., Psaty, B. M., Spector, T. D., Stefansson, K., Rivadeneira, F., Uitterlinden, A. G., Wareham, N. J., Ossowski, V., Waterworth, D., Loos, R. J. F., Karasik, D., Harris, T. B., Ohlsson, C. & Kiel, D. P. Dec 1 2017 In : Nature Communications. 8, 1, 80

Research output: Research - peer-reviewArticle

Genome-Wide Association Study
Single Nucleotide Polymorphism
Meta-Analysis
Polymorphism
Nucleotides
2 Citations

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

Willems, S. M. , Wright, D. J. , Day, F. R. , Trajanoska, K. , Joshi, P. K. , Morris, J. A. , Matteini, A. M. , Garton, F. C. , Grarup, N. , Oskolkov, N. , Thalamuthu, A. , Mangino, M. , Liu, J. , Demirkan, A. , Lek, M. , Xu, L. , Wang, G. , Oldmeadow, C. , Gaulton, K. J. , Lotta, L. A. & 142 others Miyamoto-Mikami, E., Rivas, M. A., White, T., Loh, P. R., Aadahl, M., Amin, N., Attia, J. R., Austin, K., Benyamin, B., Brage, S., Cheng, Y. C., Ciȩszczyk, P., Derave, W., Eriksson, K. F., Eynon, N., Linneberg, A., Lucia, A., Massidda, M., Mitchell, B. D., Miyachi, M., Murakami, H., Padmanabhan, S., Pandey, A., Papadimitriou, I., Rajpal, D. K., Sale, C., Schnurr, T. M., Sessa, F., Shrine, N., Tobin, M. D., Varley, I., Wain, L. V., Wray, N. R., Lindgren, C. M., MacArthur, D. G., Waterworth, D. M., McCarthy, M. I., Pedersen, O., Khaw, K. T., Kiel, D. P., Pitsiladis, Y., Fuku, N., Franks, P. W., North, K. N., Van Duijn, C. M., Mather, K. A., Hansen, T., Hansson, O., Spector, T., Murabito, J. M., Richards, J. B., Rivadeneira, F., Langenberg, C., Perry, J. R. B., Wareham, N. J., Scott, R. A., Oei, L., Zheng, H. F., Forgetta, V., Leong, A., Ahmad, O. S., Laurin, C., Mokry, L. E., Ross, S., Elks, C. E., Bowden, J., Warrington, N. M., Murray, A., Ruth, K. S., Tsilidis, K. K., Medina-Gómez, C., Estrada, K., Bis, J. C., Chasman, D. I., Demissie, S., Enneman, A. W., Hsu, Y. H., Ingvarsson, T., Kähönen, M., Kammerer, C., Lacroix, A. Z., Li, G., Liu, C. T., Liu, Y., Lorentzon, M., Mägi, R., Mihailov, E., Milani, L., Moayyeri, A., Nielson, C. M., Sham, P. C., Siggeirsdotir, K., Sigurdsson, G., Stefansson, K., Trompet, S., Thorleifsson, G., Vandenput, L., Van Der Velde, N., Viikari, J., Xiao, S. M., Zhao, J. H., Evans, D. S., Cummings, S. R., Cauley, J., Duncan, E. L., De Groot, L. C. P. G. M., Esko, T., Gudnason, V., Harris, T. B., Jackson, R. D., Jukema, J. W., Ikram, A. M. A., Karasik, D., Kaptoge, S., Kung, A. W. C., Lehtimäki, T., Lyytikäinen, L. P., Lips, P., Luben, R., Metspalu, A., Van Meurs, J. B. J., Minster, R. L., Orwoll, E., Oei, E., Psaty, B. M., Raitakari, O. T., Ralston, S. W., Ridker, P. M., Robbins, J. A., Smith, A. V., Styrkarsdottir, U., Tranah, G. J., Thorstensdottir, U., Uitterlinden, A. G., Zmuda, J., Zillikens, M. C., Ntzani, E. E., Evangelou, E., Ioannidis, J. P. A., Evans, D. M., Ohlsson, C. & GEFOS Anytype of Fracture Consortium Jul 12 2017 In : Nature Communications. 8, 16015

Research output: Research - peer-reviewArticle

fitness
loci
Signal transduction
Muscle
Genes

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis

Manousaki, D. , Dudding, T. , Haworth, S. , Hsu, Y. H. , Liu, C. T. , Medina-Gómez, C. , Voortman, T. , van der Velde, N. , Melhus, H. , Robinson-Cohen, C. , Cousminer, D. L. , Nethander, M. , Vandenput, L. , Noordam, R. , Forgetta, V. , Greenwood, C. M. T. , Biggs, M. L. , Psaty, B. M. , Rotter, J. I. , Zemel, B. S. & 33 others Mitchell, J. A., Taylor, B., Lorentzon, M., Karlsson, M., Jaddoe, V. V. W., Tiemeier, H., Campos-Obando, N., Franco, O. H., Utterlinden, A. G., Broer, L., van Schoor, N. M., Ham, A. C., Ikram, M. A., Karasik, D., de Mutsert, R., Rosendaal, F. R., den Heijer, M., Wang, T. J., Lind, L., Orwoll, E. S., Mook-Kanamori, D. O., Michaëlsson, K., Kestenbaum, B., Ohlsson, C., Mellström, D., de Groot, L. C. P. G. M., Grant, S. F. A., Kiel, D. P., Zillikens, M. C., Rivadeneira, F., Sawcer, S., Timpson, N. J. & Richards, J. B. Aug 3 2017 In : American Journal of Human Genetics. 101, 2, p. 227-238 12 p.

Research output: Research - peer-reviewArticle

Vitamin D
Multiple Sclerosis
Odds Ratio
Genome
Confidence Intervals

Low Testosterone, but Not Estradiol, Is Associated With Incident Falls in Older Men: The International MrOS Study

Vandenput, L., Mellström, D., Laughlin, G. A., Cawthon, P. M., Cauley, J. A., Hoffman, A. R., Karlsson, M. K., Rosengren, B. E., Ljunggren, Ö., Nethander, M., Eriksson, A. L., Lorentzon, M., Leung, J., Kwok, T., Orwoll, E. S. & Ohlsson, C. 2017 (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Research - peer-reviewArticle

Testosterone
Estradiol
Hong Kong
Odds Ratio
Confidence Intervals

NFAT5 and SLC4A10 loci associate with plasma osmolality

Böger, C. A. , Gorski, M. , McMahon, G. M. , Xu, H. , Chang, Y. P. C. , Van Der Most, P. J. , Navis, G. , Nolte, I. M. , De Borst, M. H. , Zhang, W. , Lehne, B. , Loh, M. , Tan, S. T. , Boerwinkle, E. , Grams, M. E. , Sekula, P. , Li, M. , Wilmot, B. , Moon, J. G. , Scheet, P. & 86 others Cucca, F., Xiao, X., Lyytikäinen, L. P., Delgado, G., Grammer, T. B., Kleber, M. E., Sedaghat, S., Rivadeneira, F., Corre, T., Kutalik, Z., Bergmann, S., Nielson, C. M., Srikanth, P., Teumer, A., Müller-Nurasyid, M., Brockhaus, A. C., Pfeufer, A., Rathmann, W., Peters, A., Matsumoto, M., De Andrade, M., Atkinson, E. J., Robinson-Cohen, C., De Boer, I. H., Hwang, S. J., Heid, I. M., Gögele, M., Concas, M. P., Tanaka, T., Bandinelli, S., Nalls, M. A., Singleton, A., Tajuddin, S. M., Adeyemo, A., Zhou, J., Doumatey, A., McWeeney, S., Murabito, J., Franceschini, N., Flessner, M., Shlipak, M., Wilson, J. G., Chen, G., Rotimi, C. N., Zonderman, A. B., Evans, M. K., Ferrucci, L., Devuyst, O., Pirastu, M., Shuldiner, A., Hicks, A. A., Pramstaller, P. P., Kestenbaum, B., Kardia, S. L. R., Turner, S. T., Study, L. C., Briske, T. E., Gieger, C., Strauch, K., Meisinger, C., Meitinger, T., Völker, U., Nauck, M., Völzke, H., Vollenweider, P., Bochud, M., Waeber, G., Kähönen, M., Lehtimäki, T., März, W., Dehghan, A., Franco, O. H., Uitterlinden, A. G., Hofman, A., Taylor, H. A., Chambers, J. C., Kooner, J. S., Fox, C. S., Hitzemann, R., Orwoll, E. S., Pattaro, C., Schlessinger, D., Köttgen, A., Snieder, H., Parsa, A. & Cohen, D. M. Aug 1 2017 In : Journal of the American Society of Nephrology. 28, 8, p. 2311-2321 11 p.

Research output: Research - peer-reviewArticle

Osmolar Concentration
Meta-Analysis
Water
Sodium
Hypernatremia

Obesity and Falls in a Prospective Study of Older Men: The Osteoporotic Fractures in Men Study

Hooker, E. R., Shrestha, S., Lee, C. G., Cawthon, P. M., Abrahamson, M., Ensrud, K., Stefanick, M. L., Dam, T. T., Marshall, L. M., Orwoll, E. S. & Nielson, C. M. Oct 1 2017 In : Journal of Aging and Health. 29, 7, p. 1235-1250 16 p.

Research output: Research - peer-reviewArticle

Osteoporotic Fractures
Obesity
Prospective Studies
Body Mass Index
Confidence Intervals

Older men with anemia have increased fracture risk independent of bone mineral density

Valderrábano, R. J., Lee, J., Lui, L. Y., Hoffman, A. R., Cummings, S. R., Orwoll, E. S. & Wu, J. Y. Jul 1 2017 In : Journal of Clinical Endocrinology and Metabolism. 102, 7, p. 2199-2206 8 p.

Research output: Research - peer-reviewArticle

Bone Density
Anemia
Minerals
Bone
Confidence Intervals

Screening for Osteoporosis in Older Men: Operating Characteristics of Proposed Strategies for Selecting Men for BMD Testing

Diem, S. J., Peters, K. W., Gourlay, M. L., Schousboe, J. T., Taylor, B. C., Orwoll, E. S., Cauley, J. A., Langsetmo, L., Crandall, C. J., Ensrud, K. E. & The Osteoporotic Fractures In Men Research Group Aug 16 2017 (Accepted/In press) In : Journal of General Internal Medicine. p. 1-7 7 p.

Research output: Research - peer-reviewArticle

Bone Density
Osteoporosis
Self-Assessment
Area Under Curve
Sensitivity and Specificity

Successful collection of stool samples for microbiome analyses from a large community-based population of elderly men

Abrahamson, M., Hooker, E., Ajami, N. J., Petrosino, J. F. & Orwoll, E. S. Sep 1 2017 In : Contemporary Clinical Trials Communications. 7, p. 158-162 5 p.

Research output: Research - peer-reviewArticle

Microbiota
Population
Gastrointestinal Microbiome
DNA
Research
2 Citations

The Association Between Protein Intake by Source and Osteoporotic Fracture in Older Men: A Prospective Cohort Study

Langsetmo, L., Shikany, J. M., Cawthon, P. M., Cauley, J. A., Taylor, B. C., Vo, T. N., Bauer, D. C., Orwoll, E. S., Schousboe, J. T. & Ensrud, K. E. 2017 (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Research - peer-reviewArticle

Osteoporotic Fractures
Cohort Studies
Prospective Studies
Proteins
Confidence Intervals

Trajectories of the relationships of physical activity with body composition changes in older men: the MrOS study

Laddu, D. R., Cawthon, P. M., Parimi, N., Hoffman, A. R., Orwoll, E., Miljkovic, I. & Stefanick, M. L. Jun 5 2017 In : BMC Geriatrics. 17, 1, 119

Research output: Research - peer-reviewArticle

Body Composition
Exercise
Fats
Weights and Measures
Independent Living
2016
5 Citations

Actigraphy- and Polysomnography-Measured Sleep Disturbances, Inflammation, and Mortality Among Older Men

Smagula, S. F., Stone, K. L., Redline, S., Ancoli-Israel, S., Barrett-Connor, E., Lane, N. E., Orwoll, E. S. & Cauley, J. A. Feb 18 2016 (Accepted/In press) In : Psychosomatic Medicine.

Research output: Research - peer-reviewArticle

Actigraphy
Polysomnography
Sleep
Inflammation
Mortality
1 Citations

Areal and volumetric bone mineral density and risk of multiple types of fracture in older men

Chalhoub, D., Orwoll, E. S., Cawthon, P. M., Ensrud, K. E., Boudreau, R., Greenspan, S., Newman, A. B., Zmuda, J., Bauer, D., Cummings, S. & Cauley, J. A. Nov 1 2016 In : Bone. 92, p. 100-106 7 p.

Research output: Research - peer-reviewArticle

Bone Density
Multiple Fractures
Spine
Femur Neck
Sternum
1 Citations

Association of 3D Geometric Measures Derived From Quantitative Computed Tomography With Hip Fracture Risk in Older Men

Borggrefe, J., de Buhr, T., Shrestha, S., Marshall, L. M., Orwoll, E., Peters, K., Black, D. M. & Glüer, C. C. Aug 1 2016 In : Journal of Bone and Mineral Research. 31, 8, p. 1550-1558 9 p.

Research output: Research - peer-reviewArticle

Hip Fractures
Tomography
Confidence Intervals
Femur Neck
Photon Absorptiometry

Association of urinary melatonin levels and aging-related outcomes in older men

Devore, E. E., Harrison, S. L., Stone, K. L., Holton, K. F., Barrett-Connor, E., Ancoli-Israel, S., Yaffe, K., Ensrud, K., Cawthon, P. M., Redline, S., Orwoll, E. & Schernhammer, E. S. Jul 1 2016 In : Sleep Medicine. 23, p. 73-80 8 p.

Research output: Research - peer-reviewArticle

Melatonin
Cognition
Mortality
Urine
Osteoporotic Fractures
7 Citations

Associations of body mass index with incident fractures and hip structural parameters in a large canadian cohort

Shen, J., Leslie, W. D., Nielson, C. M., Majumdar, S. R., Morin, S. N. & Orwoll, E. S. Feb 1 2016 In : Journal of Clinical Endocrinology and Metabolism. 101, 2, p. 476-484 9 p.

Research output: Research - peer-reviewArticle

Hip Fractures
Body Mass Index
Bone
Bone Density
Osteoporotic Fractures
5 Citations

Associations of total and free 25OHD and 1,25(OH)2D with serum markers of inflammation in older men

Srikanth, P., Chun, R. F., Hewison, M., Adams, J. S., Bouillon, R., Vanderschueren, D., Lane, N., Cawthon, P. M., Dam, T., Barrett-Connor, E., Daniels, L. B., Shikany, J. M., Stefanick, M. L., Cauley, J. A., Orwoll, E. S., Nielson, C. M. & For The Osteoporotic Fractures In Men (Mros) Study Research Group, T. O. F. I. M. . M. S. R. G. Feb 23 2016 (Accepted/In press) In : Osteoporosis International. p. 1-10 10 p.

Research output: Research - peer-reviewArticle

Free Association
Interleukin-6
Tumor Necrosis Factor-alpha
Biomarkers
Inflammation
1 Citations

Bone Density Loss Is Associated With Blood Cell Counts

Valderrábano, R. J., Lui, L. Y., Lee, J., Cummings, S. R., Orwoll, E. S., Hoffman, A. R. & Wu, J. Y. 2016 (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Research - peer-reviewArticle

Blood Cell Count
Bone Density
Anemia
Hip
Neutrophils
9 Citations

Characterization of FN1–FGFR1 and novel FN1–FGF1 fusion genes in a large series of phosphaturic mesenchymal tumors

Lee, J. C. , Su, S. Y. , Changou, C. A. , Yang, R. S. , Tsai, K. S. , Collins, M. T. , Orwoll, E. S. , Lin, C. Y. , Chen, S. H. , Shih, S. R. , Lee, C. H. , Oda, Y. , Billings, S. D. , Li, C. F. , Nielsen, G. P. , Konishi, E. , Petersson, F. , Carpenter, T. O. , Sittampalam, K. , Huang, H. Y. & 1 others Folpe, A. L. Jul 22 2016 (Accepted/In press) In : Modern Pathology.

Research output: Research - peer-reviewArticle

Fibroblast Growth Factor 1
Gene Fusion
Neoplasms
Immunohistochemistry
Proteins
5 Citations

Clinical utility of routine laboratory testing to identify possible secondary causes in older men with osteoporosis: the Osteoporotic Fractures in Men (MrOS) Study

Fink, H. A., Litwack-Harrison, S., Taylor, B. C., Bauer, D. C., Orwoll, E. S., Lee, C. G., Barrett-Connor, E., Schousboe, J. T., Kado, D. M., Garimella, P. S. & Ensrud, K. E. Jan 1 2016 In : Osteoporosis International. 27, 1, p. 331-338 8 p.

Research output: Research - peer-reviewArticle

Osteoporotic Fractures
Osteoporosis
Urine
Vitamin D
Alkaline Phosphatase

Comparison of Associations of DXA and CT Visceral Adipose Tissue Measures With Insulin Resistance, Lipid Levels, and Inflammatory Markers

Schousboe, J. T., Langsetmo, L., Schwartz, A. V., Taylor, B. C., Vo, T. N., Kats, A. M., Barrett-Connor, E., Orwoll, E. S., Marshall, L. M., Miljkovic, I., Lane, N. E. & Ensrud, K. E. Sep 1 2016 (Accepted/In press) In : Journal of Clinical Densitometry.

Research output: Research - peer-reviewArticle

Intra-Abdominal Fat
Insulin Resistance
Tomography
Lipids
Confidence Intervals
5 Citations

Degree of Trauma Differs for Major Osteoporotic Fracture Events in Older Men Versus Older Women

Ensrud, K. E., Blackwell, T. L., Cawthon, P. M., Bauer, D. C., Fink, H. A., Schousboe, J. T., Black, D. M., Orwoll, E. S., Kado, D. M., Cauley, J. A. & Mackey, D. C. Jan 1 2016 In : Journal of Bone and Mineral Research. 31, 1, p. 204-207 4 p.

Research output: Research - peer-reviewArticle

Osteoporotic Fractures
Wounds and Injuries
Wrist
Odds Ratio
Confidence Intervals

Erratum to: Clinical utility of routine laboratory testing to identify possible secondary causes in older men with osteoporosis: the osteoporotic fractures in men (MrOS) study

Fink, H. A., Litwack-Harrison, S., Taylor, B. C., Bauer, D. C., Orwoll, E. S., Lee, C. G., Barrett-Connor, E., Schousboe, J. T., Kado, D. M., Garimella, P. S., Ensrud, K. E. & For The Osteoporotic Fractures In Men (Mros) Study Group, T. O. F. I. M. . M. S. G. Oct 20 2016 (Accepted/In press) In : Osteoporosis International. p. 1-2 2 p.

Research output: Research - peer-reviewArticle

6 Citations

Establishing a framework-does testosterone supplementation help older men?

Orwoll, E. S. Feb 18 2016 In : New England Journal of Medicine. 374, 7, p. 682-683 2 p.

Research output: Research - peer-reviewArticle

37 Citations

Free 25-hydroxyvitamin D: Impact of vitamin D binding protein assays on racial-genotypic associations

Nielson, C. M. , Jones, K. S. , Chun, R. F. , Jacobs, J. M. , Wang, Y. , Hewison, M. , Adams, J. S. , Swanson, C. M. , Lee, C. G. , Vanderschueren, D. , Pauwels, S. , Prentice, A. , Smith, R. D. , Shi, T. , Gao, Y. , Schepmoes, A. A. , Zmuda, J. M. , Lapidus, J. , Cauley, J. A. , Bouillon, R. & 2 others Schoenmakers, I. & Orwoll, E. S. May 1 2016 In : Journal of Clinical Endocrinology and Metabolism. 101, 5, p. 2226-2234 9 p.

Research output: Research - peer-reviewArticle

Vitamin D-Binding Protein
Vitamin D
African Americans
25-hydroxyvitamin D
Assays

Impact of Competing Risk of Mortality on Association of Weight Loss With Risk of Central Body Fractures in Older Men: A Prospective Cohort Study

Ensrud, K. E., Harrison, S. L., Cauley, J. A., Langsetmo, L., Schousboe, J. T., Kado, D. M., Gourlay, M. L., Lyons, J. G., Fredman, L., Napoli, N., Crandall, C. J., Lewis, C. E., Orwoll, E. S., Stefanick, M. L. & Cawthon, P. M. 2016 (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Research - peer-reviewArticle

Weight Loss
Cohort Studies
Prospective Studies
Mortality
Hip Fractures
6 Citations

Inflammatory Markers and the Risk of Hip and Vertebral Fractures in Men: The Osteoporotic Fractures in Men (MrOS)

Cauley, J. A., Barbour, K. E., Harrison, S. L., Cloonan, Y. K., Danielson, M. E., Ensrud, K. E., Fink, H. A., Orwoll, E. S. & Boudreau, R. 2016 (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Research - peer-reviewArticle

Osteoporotic Fractures
Hip Fractures
Hip
Interleukins
Interleukin-10
3 Citations

Lower Urinary Tract Symptoms and Risk of Nonspine Fractures among Older Community Dwelling U.S. Men

Marshall, L. M., Lapidus, J. A., Wiedrick, J., Barrett-Connor, E., Bauer, D. C., Orwoll, E. S. & Parsons, J. K. 2016 (Accepted/In press) In : Journal of Urology.

Research output: Research - peer-reviewArticle

Independent Living
Lower Urinary Tract Symptoms
Pelvic Bones
Bone Density
Nocturia
25 Citations

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

Lu, Y. , Day, F. R. , Gustafsson, S. , Buchkovich, M. L. , Na, J. , Bataille, V. , Cousminer, D. L. , Dastani, Z. , Drong, A. W. , Esko, T. , Evans, D. M. , Falchi, M. , Feitosa, M. F. , Ferreira, T. , Hedman, Å. K. , Haring, R. , Hysi, P. G. , Iles, M. M. , Justice, A. E. , Kanoni, S. & 239 others Lagou, V., Li, R., Li, X., Locke, A., Lu, C., Mägi, R., Perry, J. R. B., Pers, T. H., Qi, Q., Sanna, M., Schmidt, E. M., Scott, W. R., Shungin, D., Teumer, A., Vinkhuyzen, A. A. E., Walker, R. W., Westra, H. J., Zhang, M., Zhang, W., Zhao, J. H., Zhu, Z., Afzal, U., Ahluwalia, T. S., Bakker, S. J. L., Bellis, C., Bonnefond, A., Borodulin, K., Buchman, A. S., Cederholm, T., Choh, A. C., Choi, H. J., Curran, J. E., De Groot, L. C. P. G. M., De Jager, P. L., Dhonukshe-Rutten, R. A. M., Enneman, A. W., Eury, E., Evans, D. S., Forsen, T., Friedrich, N., Fumeron, F., Garcia, M. E., Gärtner, S., Han, B. G., Havulinna, A. S., Hayward, C., Hernandez, D., Hillege, H., Ittermann, T., Kent, J. W., Kolcic, I., Laatikainen, T., Lahti, J., Leach, I. M., Lee, C. G., Lee, J. Y., Liu, T., Liu, Y., Lobbens, S., Loh, M., Lyytikaïnen, L. P., Medina-Gomez, C., Michaëlsson, K., Nalls, M. A., Nielson, C. M., Oozageer, L., Pascoe, L., Paternoster, L., Polašek, O., Ripatti, S., Sarzynski, M. A., Shin, C. S., Naranäiä, N. S., Spira, D., Srikanth, P., Steinhagen-Thiessen, E., Sung, Y. J., Swart, K. M. A., Taittonen, L., Tanaka, T., Tikkanen, E., Van Der Velde, N., Van Schoor, N. M., Verweij, N., Wright, A. F., Yu, L., Zmuda, J. M., Eklund, N., Forrester, T., Grarup, N., Jackson, A. U., Kristiansson, K., Kuulasmaa, T., Kuusisto, J., Lichtner, P., Luan, J., Mahajan, A., Männistö, S., Palmer, C. D., Ried, J. S., Scott, R. A., Stancáková, A., Wagner, P. J., Demirkan, A., Döring, A., Gudnason, V., Kiel, D. P., Kühnel, B., Mangino, M., McKnight, B., Menni, C., O'Connell, J. R., Oostra, B. A., Shuldiner, A. R., Song, K., Vandenput, L., Van Duijn, C. M., Vollenweider, P., White, C. C., Boehnke, M., Boettcher, Y., Cooper, R. S., Forouhi, N. G., Gieger, C., Grallert, H., Hingorani, A., Jørgensen, T., Jousilahti, P., Kivimaki, M., Kumari, M., Laakso, M., Langenberg, C., Linneberg, A., Luke, A., McKenzie, C. A., Palotie, A., Pedersen, O., Peters, A., Strauch, K., Tayo, B. O., Wareham, N. J., Bennett, D. A., Bertram, L., Blangero, J., Blüher, M., Bouchard, C., Campbell, H., Cho, N. H., Cummings, S. R., Czerwinski, S. A., Demuth, I., Eckardt, R., Eriksson, J. G., Ferrucci, L., Franco, O. H., Froguel, P., Gansevoort, R. T., Hansen, T., Harris, T. B., Hastie, N., Heliövaara, M., Hofman, A., Jordan, J. M., Jula, A., Kähönen, M., Kajantie, E., Knekt, P. B., Koskinen, S., Kovacs, P., Lehtimäki, T., Lind, L., Liu, Y., Orwoll, E. S., Osmond, C., Perola, M., Pérusse, L., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Rivadeneira, F., Rudan, I., Salomaa, V., Sørensen, T. I. A., Stumvoll, M., Tönjes, A., Towne, B., Tranah, G. J., Tremblay, A., Uitterlinden, A. G., Van Der Harst, P., Vartiainen, E., Viikari, J. S., Vitart, V., Vohl, M. C., Völzke, H., Walker, M., Wallaschofski, H., Wild, S., Wilson, J. F., Yengo, L., Bishop, D. T., Borecki, I. B., Chambers, J. C., Cupples, L. A., Dehghan, A., Deloukas, P., Fatemifar, G., Fox, C., Furey, T. S., Franke, L., Han, J., Hunter, D. J., Karjalainen, J., Karpe, F., Kaplan, R. C., Kooner, J. S., McCarthy, M. I., Murabito, J. M., Morris, A. P., Bishop, J. A. N., North, K. E., Ohlsson, C., Ong, K. K., Prokopenko, I., Richards, J. B., Schadt, E. E., Spector, T. D., Widén, E., Willer, C. J., Yang, J., Ingelsson, E., Mohlke, K. L., Hirschhorn, J. N., Pospisilik, J. A., Zillikens, M. C., Lindgren, C., Kilpelaïnen, T. O. & Loos, R. J. F. Feb 1 2016 In : Nature Communications. 7, 10495

Research output: Research - peer-reviewArticle

Adiposity
Adipose Tissue
fats
loci
Fats
6 Citations

Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2

Nielson, C. M. , Liu, C. T. , Smith, A. V. , Ackert-Bicknell, C. L. , Reppe, S. , Jakobsdottir, J. , Wassel, C. , Register, T. C. , Oei, L. , Alonso, N. , Oei, E. H. , Parimi, N. , Samelson, E. J. , Nalls, M. A. , Zmuda, J. , Lang, T. , Bouxsein, M. , Latourelle, J. , Claussnitzer, M. , Siggeirsdottir, K. & 31 others Srikanth, P., Lorentzen, E., Vandenput, L., Langefeld, C., Raffield, L., Terry, G., Cox, A. J., Allison, M. A., Criqui, M. H., Bowden, D., Ikram, M. A., Mellström, D., Karlsson, M. K., Carr, J., Budoff, M., Phillips, C., Cupples, L. A., Chou, W. C., Myers, R. H., Ralston, S. H., Gautvik, K. M., Cawthon, P. M., Cummings, S., Karasik, D., Rivadeneira, F., Gudnason, V., Orwoll, E. S., Harris, T. B., Ohlsson, C., Kiel, D. P. & Hsu, Y. H. Dec 1 2016 In : Journal of Bone and Mineral Research. 31, 12, p. 2085-2097 13 p.

Research output: Research - peer-reviewArticle

Genome-Wide Association Study
Single Nucleotide Polymorphism
Bone and Bones
Quantitative Trait Loci
Osteoblasts
1 Citations

Operator variability in scan positioning is a major component of HR-pQCT precision error and is reduced by standardized training

Bonaretti, S., Vilayphiou, N., Chan, C. M., Yu, A., Nishiyama, K., Liu, D., Boutroy, S., Ghasem-Zadeh, A., Boyd, S. K., Chapurlat, R., McKay, H., Shane, E., Bouxsein, M. L., Black, D. M., Majumdar, S., Orwoll, E. S., Lang, T. F., Khosla, S. & Burghardt, A. J. Jul 30 2016 (Accepted/In press) In : Osteoporosis International. p. 1-13 13 p.

Research output: Research - peer-reviewArticle

Software
Tomography
Bone Fractures
Tibia
Radiology
4 Citations

Osteoporosis in men: findings from the Osteoporotic Fractures in Men Study (MrOS)

Cawthon, P. M., Shahnazari, M., Orwoll, E. S. & Lane, N. E. Feb 1 2016 In : Therapeutic Advances in Musculoskeletal Disease. 8, 1, p. 15-27 13 p.

Research output: Research - peer-reviewArticle

Osteoporotic Fractures
Osteoporosis
Bone Fractures
Public Health
Mortality
4 Citations

Passing the baton - Harnessing the full value of older scientists

Orwoll, E. Jun 30 2016 In : New England Journal of Medicine. 374, 26, p. 2514-2517 4 p.

Research output: Research - peer-reviewReview article