Dong Zhang

Research Assistant Professor

Research Assistant Professor, Cell, Developmental, & Cancer Biology

Emailzhangdo@ohsu.edu

379 Citations
9 h-Index

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5 Similar Profiles

Ovarian Neoplasms Medicine & Life Sciences

Neoplasms Medicine & Life Sciences

Y-Box-Binding Protein 1 Medicine & Life Sciences

Up-Regulation Medicine & Life Sciences

Mitogen-Activated Protein Kinase Kinases Medicine & Life Sciences

Isogeneic Transplantation Medicine & Life Sciences

Adenosine Diphosphate Ribose Medicine & Life Sciences

Breast Neoplasms Medicine & Life Sciences

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Research Output 2011 2019

379 Citations
9 h-Index
11 Article

6 Citations (Scopus)

Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy

Fang, Y., McGrail, D. J., Sun, C., Labrie, M., Chen, X., Zhang, D., Ju, Z., Vellano, C. P., Lu, Y., Li, Y., Jeong, K. J., Ding, Z., Liang, J., Wang, S. W., Dai, H., Lee, S., Sahni, N., Mercado-Uribe, I., Kim, T. B., Chen, K. & 7 others, Lin, S. Y., Peng, G., Westin, S. N., Liu, J., O'Connor, M. J., Yap, T. A. & Mills, G., Jun 10 2019, In : Cancer Cell. 35, 6, p. 851-867.e7

Research output: Contribution to journal › Article

Open Access

DNA Damage

Poly(ADP-ribose) Polymerases

Heterografts

Neoplasms

Therapeutics

30 Citations (Scopus)

BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency

Sun, C., Yin, J., Fang, Y., Chen, J., Jeong, K. J., Chen, X., Vellano, C. P., Ju, Z., Zhao, W., Zhang, D., Lu, Y., Meric-Bernstam, F., Yap, T. A., Hattersley, M., O'Connor, M. J., Chen, H., Fawell, S., Lin, S. Y., Peng, G. & Mills, G., Mar 12 2018, In : Cancer Cell. 33, 3, p. 401-416.e8

Research output: Contribution to journal › Article

Homologous Recombination

Mutation

Poly(ADP-ribose) Polymerase Inhibitors

Protein C

Neoplasms

5 Citations (Scopus)

A murine preclinical syngeneic transplantation model for breast cancer precision medicine

Federico, L., Chong, Z., Zhang, D., McGrail, D. J., Zhao, W., Jeong, K. J., Vellano, C. P., Ju, Z., Gagea, M., Liu, S., Mitra, S., Dennison, J. B., Lorenzi, P. L., Cardnell, R., Diao, L., Wang, J., Lu, Y., Byers, L. A., Perou, C. M., Lin, S. Y. & 1 others, Mills, G., Apr 1 2017, In : Science advances. 3, 4, e1600957.

Research output: Contribution to journal › Article

Isogeneic Transplantation

Precision Medicine

Breast Neoplasms

Transplants

Adenosine

37 Citations (Scopus)

Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers

Sun, C., Fang, Y., Yin, J., Chen, J., Ju, Z., Zhang, D., Chen, X., Vellano, C. P., Jeong, K. J., Ng, P. K. S., Eterovic, A. K. B., Bhola, N. H., Lu, Y., Westin, S. N., Grandis, J. R., Lin, S. Y., Scott, K. L., Peng, G., Brugge, J. & Mills, G., May 31 2017, In : Science Translational Medicine. 9, 392, aal5148.

Research output: Contribution to journal › Article

Adenosine Diphosphate Ribose

Mitogen-Activated Protein Kinase Kinases

Neoplasms

DNA Damage

Recombinational DNA Repair

15 Citations (Scopus)

YAP/TAZ-mediated upregulation of GAB2 leads to increased sensitivity to growth factor-induced activation of the PI3K pathway

Wang, C., Gu, C., Jeong, K. J., Zhang, D., Guo, W., Lu, Y., Ju, Z., Panupinthu, N., Yang, J. Y., Gagea, M. M., Ng, P. K. S., Zhang, F. & Mills, G., Jan 1 2017, In : Cancer Research. 77, 7, p. 1637-1648 12 p.

Research output: Contribution to journal › Article

Endometrial Neoplasms

Phosphatidylinositol 3-Kinases

Intercellular Signaling Peptides and Proteins

Up-Regulation

Neoplasms