Dong Zhang

Research Assistant Professor

  • 379 Citations
  • 9 h-Index
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Fingerprint Dive into the research topics where Dong Zhang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Ovarian Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Y-Box-Binding Protein 1 Medicine & Life Sciences
Up-Regulation Medicine & Life Sciences
Mitogen-Activated Protein Kinase Kinases Medicine & Life Sciences
Isogeneic Transplantation Medicine & Life Sciences
Adenosine Diphosphate Ribose Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences

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Research Output 2011 2019

  • 379 Citations
  • 9 h-Index
  • 11 Article
6 Citations (Scopus)

Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy

Fang, Y., McGrail, D. J., Sun, C., Labrie, M., Chen, X., Zhang, D., Ju, Z., Vellano, C. P., Lu, Y., Li, Y., Jeong, K. J., Ding, Z., Liang, J., Wang, S. W., Dai, H., Lee, S., Sahni, N., Mercado-Uribe, I., Kim, T. B., Chen, K. & 7 others, Lin, S. Y., Peng, G., Westin, S. N., Liu, J., O'Connor, M. J., Yap, T. A. & Mills, G., Jun 10 2019, In : Cancer Cell. 35, 6, p. 851-867.e7

Research output: Contribution to journalArticle

Open Access
DNA Damage
Poly(ADP-ribose) Polymerases
30 Citations (Scopus)

BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency

Sun, C., Yin, J., Fang, Y., Chen, J., Jeong, K. J., Chen, X., Vellano, C. P., Ju, Z., Zhao, W., Zhang, D., Lu, Y., Meric-Bernstam, F., Yap, T. A., Hattersley, M., O'Connor, M. J., Chen, H., Fawell, S., Lin, S. Y., Peng, G. & Mills, G., Mar 12 2018, In : Cancer Cell. 33, 3, p. 401-416.e8

Research output: Contribution to journalArticle

Homologous Recombination
Poly(ADP-ribose) Polymerase Inhibitors
Protein C
5 Citations (Scopus)

A murine preclinical syngeneic transplantation model for breast cancer precision medicine

Federico, L., Chong, Z., Zhang, D., McGrail, D. J., Zhao, W., Jeong, K. J., Vellano, C. P., Ju, Z., Gagea, M., Liu, S., Mitra, S., Dennison, J. B., Lorenzi, P. L., Cardnell, R., Diao, L., Wang, J., Lu, Y., Byers, L. A., Perou, C. M., Lin, S. Y. & 1 others, Mills, G., Apr 1 2017, In : Science advances. 3, 4, e1600957.

Research output: Contribution to journalArticle

Isogeneic Transplantation
Precision Medicine
Breast Neoplasms
37 Citations (Scopus)

Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers

Sun, C., Fang, Y., Yin, J., Chen, J., Ju, Z., Zhang, D., Chen, X., Vellano, C. P., Jeong, K. J., Ng, P. K. S., Eterovic, A. K. B., Bhola, N. H., Lu, Y., Westin, S. N., Grandis, J. R., Lin, S. Y., Scott, K. L., Peng, G., Brugge, J. & Mills, G., May 31 2017, In : Science Translational Medicine. 9, 392, aal5148.

Research output: Contribution to journalArticle

Adenosine Diphosphate Ribose
Mitogen-Activated Protein Kinase Kinases
DNA Damage
Recombinational DNA Repair
15 Citations (Scopus)

YAP/TAZ-mediated upregulation of GAB2 leads to increased sensitivity to growth factor-induced activation of the PI3K pathway

Wang, C., Gu, C., Jeong, K. J., Zhang, D., Guo, W., Lu, Y., Ju, Z., Panupinthu, N., Yang, J. Y., Gagea, M. M., Ng, P. K. S., Zhang, F. & Mills, G., Jan 1 2017, In : Cancer Research. 77, 7, p. 1637-1648 12 p.

Research output: Contribution to journalArticle

Endometrial Neoplasms
Phosphatidylinositol 3-Kinases
Intercellular Signaling Peptides and Proteins