Diana Ortiz-Garcia

Research output

Research output per year 1990 1990 1995 1997 2000 2001 2003 2007 2009 2010 2015 2016 2017 2020 2021 2021

• 16 Article

Research output per year

Research output per year

Search results

• Vaccinia Virus Vectors Targeting Peptides for MHC Class II Presentation to CD4⁺ T Cells

  Hobbs, S. J., Harbour, J. C., Yates, P. A., Ortiz, D., Landfear, S. M. & Nolz, J. C., Jan 1 2020, In: ImmunoHorizons. 4, 1, p. 1-13 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Vaccinia virus 100%
  • Histocompatibility Antigens Class II 92%
  • T-Lymphocytes 51%
  • Immunization 12%
  • invariant chain 11%
  2 Scopus citations

• Two novel nucleobase/pentamidine transporters from Trypanosoma brucei

  Ortiz, D., Sanchez, M., Quecke, P. & Landfear, S. M., Feb 2009, In: Molecular and Biochemical Parasitology. 163, 2, p. 67-76 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Pentamidine 100%
  • Trypanosoma brucei brucei 90%
  • Trypanosoma brucei 86%
  • nucleobases 85%
  • Purine Nucleosides 68%
  22 Scopus citations

• Tetracycline-inducible gene expression in Trichomonas vaginalis

  Ortiz, D. & Johnson, P. J., Apr 25 2003, In: Molecular and Biochemical Parasitology. 128, 1, p. 43-49 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Trichomonas vaginalis 100%
  • chloramphenicol acetyltransferase 92%
  • Tetracycline 75%
  • tetracycline 71%
  • Chloramphenicol 64%
  7 Scopus citations

• Targeting the cytochrome bc₁ complex of Leishmania parasites for discovery of novel drugs

  Ortiz, D., Forquer, I., Boitz, J., Soysa, R., Elya, C., Fulwiler, A., Nilsen, A., Polley, T., Riscoe, M. K., Ullman, B. & Landfear, S. M., Aug 2016, In: Antimicrobial agents and chemotherapy. 60, 8, p. 4972-4982 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Electron Transport Complex III 100%
  • buparvaquone 91%
  • Leishmania 81%
  • Quinolones 81%
  • Drug Discovery 72%
  21 Scopus citations

• Purine restriction induces pronounced translational upregulation of the NT1 adenosine/pyrimidine nucleoside transporter in Leishmania major

  Ortiz, D., Valdés, R., Sanchez, M., Hayenga, J., Elya, C., Detke, S. & Landfear, S. M., Oct 2010, In: Molecular Microbiology. 78, 1, p. 108-118 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Pyrimidine Nucleosides 100%
  • Nucleoside Transport Proteins 95%
  • Leishmania major 85%
  • Purines 85%
  • purine 72%
  17 Scopus citations

• Possible role of transcribed intergenic sequences in Entamoeba histolytica

  Ortiz-Garcia, D., Meraz, M. A. & Meza, I., 1997, In: Archives of Medical Research. 28, p. 30-31 2 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

  Van Voorhis, W. C., Adams, J. H., Adelfio, R., Ahyong, V., Akabas, M. H., Alano, P., Alday, A., Alemán Resto, Y., Alsibaee, A., Alzualde, A., Andrews, K. T., Avery, S. V., Avery, V. M., Ayong, L., Baker, M., Baker, S., Ben Mamoun, C., Bhatia, S., Bickle, Q., Bounaadja, L., & 167 othersBowling, T., Bosch, J., Boucher, L. E., Boyom, F. F., Brea, J., Brennan, M., Burton, A., Caffrey, C. R., Camarda, G., Carrasquilla, M., Carter, D., Belen Cassera, M., Chih-Chien Cheng, K., Chindaudomsate, W., Chubb, A., Colon, B. L., Colón-López, D. D., Corbett, Y., Crowther, G. J., Cowan, N., D’Alessandro, S., Le Dang, N., Delves, M., DeRisi, J. L., Du, A. Y., Duffy, S., Abd El-Salam El-Sayed, S., Ferdig, M. T., Fernández Robledo, J. A., Fidock, D. A., Florent, I., Fokou, P. V. T., Galstian, A., Gamo, F. J., Gokool, S., Gold, B., Golub, T., Goldgof, G. M., Guha, R., Guiguemde, W. A., Gural, N., Guy, R. K., Hansen, M. A. E., Hanson, K. K., Hemphill, A., Hooft van Huijsduijnen, R., Horii, T., Horrocks, P., Hughes, T. B., Huston, C., Igarashi, I., Ingram-Sieber, K., Itoe, M. A., Jadhav, A., Naranuntarat Jensen, A., Jensen, L. T., Jiang, R. H. Y., Kaiser, A., Keiser, J., Ketas, T., Kicka, S., Kim, S., Kirk, K., Kumar, V. P., Kyle, D. E., Lafuente, M. J., Landfear, S., Lee, N., Lee, S., Lehane, A. M., Li, F., Little, D., Liu, L., Llinás, M., Loza, M. I., Lubar, A., Lucantoni, L., Lucet, I., Maes, L., Mancama, D., Mansour, N. R., March, S., McGowan, S., Medina Vera, I., Meister, S., Mercer, L., Mestres, J., Mfopa, A. N., Misra, R. N., Moon, S., Moore, J. P., Morais Rodrigues da Costa, F., Müller, J., Muriana, A., Nakazawa Hewitt, S., Nare, B., Nathan, C., Narraidoo, N., Nawaratna, S., Ojo, K. K., Ortiz, D., Panic, G., Papadatos, G., Parapini, S., Patra, K., Pham, N., Prats, S., Plouffe, D. M., Poulsen, S. A., Pradhan, A., Quevedo, C., Quinn, R. J., Rice, C. A., Rizk, M. A., Ruecker, A., St. Onge, R., Salgado Ferreira, R., Samra, J., Robinett, N. G., Schlecht, U., Schmitt, M., Silva Villela, F., Silvestrini, F., Sinden, R., Smith, D. A., Soldati, T., Spitzmüller, A., Stamm, S. M., Sullivan, D. J., Sullivan, W., Suresh, S., Suzuki, B. M., Suzuki, Y., Swamidass, S. J., Taramelli, D., Tchokouaha, L. R. Y., Theron, A., Thomas, D., Tonissen, K. F., Townson, S., Tripathi, A. K., Trofimov, V., Udenze, K. O., Ullah, I., Vallieres, C., Vigil, E., Vinetz, J. M., Voong Vinh, P., Vu, H., Watanabe, N. A., Weatherby, K., White, P. M., Wilks, A. F., Winzeler, E. A., Wojcik, E., Wree, M., Wu, W., Yokoyama, N., Zollo, P. H. A., Abla, N., Blasco, B., Burrows, J., Laleu, B., Leroy, D., Spangenberg, T., Wells, T. & Willis, P. A., Jul 2016, In: PLoS pathogens. 12, 7, e1005763.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neglected Diseases 100%
  • Drug Discovery 77%
  • malaria 76%
  • Malaria 68%
  • Pharmaceutical Chemistry 61%
  170 Scopus citations

• New approaches in the dianosis of taenia solium cysticercosis and taeniasis

  Flisser, A., Plancarte, A., Correa, D., Rodriguez-Del-Rosal Feldman, E. M., Sandoval, M., Torres, A., Meza, A., Parkhouse, R. M. E., Harrison, L. J. S., Wilson, M., Avila, G., Allan, J., Craig, P. S., Vallejo, V., Ortiz, D., Garcia, E. & McManus, D. P., 1990, In: Annales de Parasitologie Humaine et Comparee. 65, SUPPL. 1, p. 95-98 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  28 Scopus citations

• Molecular genetic analysis of purine nucleobase transport in Leishmania major

  Ortiz, D., Sanchez, M., Pierce, S., Herrmann, T., Kimblin, N., Archie Bouwer, H. G. & Landfear, S. M., Jun 2007, In: Molecular Microbiology. 64, 5, p. 1228-1243 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Leishmania major 100%
  • Membrane Transport Proteins 91%
  • purine 85%
  • Purines 66%
  • Molecular Biology 60%
  33 Scopus citations

• Isolation and characterization of species-specific DNA probes from Taenia solium and Taenia saginata and their use in an egg detection assay

  Chapman, A., Vallejo, V., Mossie, K. G., Ortiz, D., Agabian, N. & Flisser, A., 1995, In: Journal of Clinical Microbiology. 33, 5, p. 1283-1288 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Taenia saginata 100%
  • Taenia solium 87%
  • DNA Probes 71%
  • Ovum 60%
  • Taenia 35%
  51 Scopus citations

• Initiator recognition in a primitive eukaryote: IBP39, an initiator-binding protein from Trichomonas vaginalis

  Liston, D. R., Lau, A. O. T., Ortiz, D., Smale, S. T. & Johnson, P. J., 2001, In: Molecular and cellular biology. 21, 22, p. 7872-7882 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Trichomonas vaginalis 100%
  • Eukaryota 76%
  • Carrier Proteins 62%
  • Amino Acid Sequence Homology 25%
  • Genes 22%
  35 Scopus citations

• Identification of selective inhibitors of the Plasmodium falciparum hexose transporter PfHT by screening focused libraries of anti-malarial compounds

  Ortiz, D., Guiguemde, W. A., Johnson, A., Elya, C., Anderson, J., Clark, J., Connelly, M., Yang, L., Min, J., Sato, Y., Guy, R. K. & Landfear, S. M., Apr 20 2015, In: PloS one. 10, 4, e0123598.

  Research output: Contribution to journal › Article › peer-review

  • Monosaccharide Transport Proteins 100%
  • monosaccharide transport proteins 92%
  • Hexose 72%
  • antimalarials 72%
  • Plasmodium falciparum 71%
  22 Scopus citations

• Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening

  Ortiz, D., Armand Guiguemde, W., Hammill, J. T., Carrillo, A. K., Chen, Y., Connelly, M., Stalheim, K., Elya, C., Johnson, A., Min, J., Shelat, A., Smithson, D. C., Yang, L., Zhu, F., Kiplin Guy, R. & Landfear, S. M., 2017, In: PLoS neglected tropical diseases. 11, 12, e0006157.

  Research output: Contribution to journal › Article › peer-review

  • drug therapy 100%
  • Leishmaniasis 80%
  • Parasitic Diseases 74%
  • Parasites 57%
  • SYBR Green I 54%
  14 Scopus citations

• An acid-activated nucleobase transporter from Leishmania major

  Ortiz, D., Sanchez, M., Koch, H. P., Larson, H. P. & Landfear, S. M., Jun 12 2009, In: Journal of Biological Chemistry. 284, 24, p. 16164-16169 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Leishmania major 100%
  • Nucleobase 80%
  • Purine Nucleobase 60%
  • Acids 55%
  • purine 42%
  26 Scopus citations

• Amino-Substituted 3-Aryl- And 3-Heteroarylquinolines as Potential Antileishmanial Agents

  Hammill, J. T., Sviripa, V. M., Kril, L. M., Ortiz, D., Fargo, C. M., Kim, H. S., Chen, Y., Rector, J., Rice, A. L., Domagalska, M. A., Begley, K. L., Liu, C., Rangnekar, V. M., Dujardin, J. C., Watt, D. S., Landfear, S. M. & Guy, R. K., Aug 26 2021, In: Journal of Medicinal Chemistry. 64, 16, p. 12152-12162 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Antileishmanial Agent 100%
  • Parasites 53%
  • Leishmaniasis 50%
  • Leishmania 50%
  • Drug 34%

• Actin induction during PMA and cAMP-dependent signal pathway activation in Entamoeba histolytica trophozoites

  Ortiz, D., Del Carmen Dominguez-Robles, M., Villegas-Sepúlveda, N. & Meza, I., 2000, In: Cellular Microbiology. 2, 5, p. 391-400 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Entamoeba histolytica 100%
  • Trophozoites 98%
  • Actins 64%
  • Signal Transduction 59%
  • Nucleic Acid Regulatory Sequences 38%
  9 Scopus citations