Research Output 1979 2018

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Article
2018
Thioctic Acid
Relapsing-Remitting Multiple Sclerosis
Monocytes
Blood Cells
B-Lymphocytes
2017
2 Citations

Early Fever As a Predictor of Paroxysmal Sympathetic Hyperactivity in Traumatic Brain Injury

Hinson, H. E., Schreiber, M. A., Laurie, A. L., Baguley, I. J., Bourdette, D. & Ling, G. S. F. Jan 5 2017 (Accepted/In press) In : Journal of Head Trauma Rehabilitation.

Research output: Research - peer-reviewArticle

Fever
Traumatic Brain Injury
Vital Signs
Decerebrate State
Tachypnea
2 Citations

Ester-to-amide rearrangement of ethanolamine-derived prodrugs of sobetirome with increased blood-brain barrier penetration

Ferrara, S. J., Meinig, J. M., Placzek, A. T., Banerji, T., McTigue, P., Hartley, M. D., Sanford-Crane, H. S., Banerji, T., Bourdette, D. & Scanlan, T. S. May 15 2017 In : Bioorganic and Medicinal Chemistry. 25, 10, p. 2743-2753 11 p.

Research output: Research - peer-reviewArticle

Ethanolamine
Prodrugs
Blood-Brain Barrier
Amides
Esters

Lipoic acid in secondary progressive MS

Spain, R., Powers, K., Murchison, C., Heriza, E., Winges, K., Yadav, V., Cameron, M., Kim, E., Horak, F., Simon, J. & Bourdette, D. 2017 In : Neurology: Neuroimmunology and NeuroInflammation. 4, 5, 374

Research output: Research - peer-reviewArticle

Thioctic Acid
Brain
Atrophy
Placebos
Compliance

Lipoic Acid Stimulates cAMP Production in Healthy Control and Secondary Progressive MS Subjects

Fiedler, S. E., Yadav, V., Kerns, A. R., Tsang, C., Markwardt, S., Kim, E., Spain, R., Bourdette, D. & Salinthone, S. Nov 15 2017 (Accepted/In press) In : Molecular Neurobiology. p. 1-13 13 p.

Research output: Research - peer-reviewArticle

Chronic Progressive Multiple Sclerosis
Thioctic Acid
Cyclic AMP
Multiple Sclerosis
Anti-Inflammatory Agents

MIF and D-DT are potential disease severity modifiers in male MS subjects

Benedek, G. , Meza-Romero, R. , Jordan, K. , Zhang, Y. , Nguyen, H. , Kent, G. , Li, J. , Siu, E. , Frazer, J. , Piecychna, M. , Du, X. , Sreih, A. , Leng, L. , Wiedrick, J. , Caillier, S. J. , Offner, H. , Oksenberg, J. R. , Yadav, V. , Bourdette, D. , Bucala, R. & 1 others Vandenbark, A. A. Oct 3 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 40, p. E8421-E8429

Research output: Research - peer-reviewArticle

Multiple Sclerosis
dopachrome isomerase
Therapeutics
Macrophage Migration-Inhibitory Factors
Sex Factors
1 Citations

Sex-dependent treatment of chronic EAE with partial MHC class II constructs

Benedek, G., Chaudhary, P., Meza-Romero, R., Calkins, E., Kent, G., Offner, H., Bourdette, D. & Vandenbark, A. A. May 6 2017 In : Journal of Neuroinflammation. 14, 1, 100

Research output: Research - peer-reviewArticle

Autoimmune Experimental Encephalomyelitis
Multiple Sclerosis
Central Nervous System
Relapsing-Remitting Multiple Sclerosis
Estrogen Receptor alpha
1 Citations

Sleep and its associations with perceived and objective cognitive impairment in individuals with multiple sclerosis

Hughes, A. J., Parmenter, B. A., Haselkorn, J. K., Lovera, J. F., Bourdette, D., Boudreau, E., Cameron, M. H. & Turner, A. P. Aug 1 2017 In : Journal of Sleep Research. 26, 4, p. 428-435 8 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Sleep
Cognitive Dysfunction
Cognition
Sex Education

Targeting Fatty-Acid Amide Hydrolase with Prodrugs for CNS-Selective Therapy

Meinig, J. M., Ferrara, S. J., Banerji, T., Banerji, T., Sanford-Crane, H. S., Bourdette, D. & Scanlan, T. S. Nov 15 2017 In : ACS Chemical Neuroscience. 8, 11, p. 2468-2476 9 p.

Research output: Research - peer-reviewArticle

Prodrugs
Pharmaceutical Preparations
Therapeutics
fatty-acid amide hydrolase
GC 1 compound
2 Citations

Trends and characteristics of US Medicare spending on repository corticotropin

Hartung, D. M., Johnston, K., Van Leuven, S., Deodhar, A., Cohen, D. M. & Bourdette, D. N. Nov 1 2017 In : JAMA Internal Medicine. 177, 11, p. 1680-1682 3 p.

Research output: Research - peer-reviewArticle

Medicare
Adrenocorticotropic Hormone
2016
3 Citations

Dimethyl fumarate activates the prostaglandin EP2 receptor and stimulates cAMP signaling in human peripheral blood mononuclear cells

Fiedler, S. E., Kerns, A. R., Tsang, C., Tsang, V., Bourdette, D. & Salinthone, S. Jun 17 2016 In : Biochemical and Biophysical Research Communications. 475, 1, p. 19-24 6 p.

Research output: Research - peer-reviewArticle

Prostaglandin Receptors
Cyclic AMP
Blood Cells
Dimethyl Fumarate
Prostaglandins
3 Citations

Immunopathology of Japanese macaque encephalomyelitis is similar to multiple sclerosis

Blair, T. C., Manoharan, M., Rawlings-Rhea, S. D., Tagge, I., Kohama, S. G., Hollister-Smith, J., Ferguson, B., Woltjer, R. L., Frederick, M. C., Pollaro, J., Rooney, W. D., Sherman, L. S., Bourdette, D. N. & Wong, S. W. Feb 15 2016 In : Journal of Neuroimmunology. 291, p. 1-10 10 p.

Research output: Research - peer-reviewArticle

Encephalomyelitis
Macaca
Multiple Sclerosis
Central Nervous System
T-Lymphocytes
5 Citations

Low-fat, plant-based diet in multiple sclerosis: A randomized controlled trial

Yadav, V., Marracci, G., Kim, E., Spain, R., Cameron, M., Overs, S., Riddehough, A., Li, D. K. B., McDougall, J., Lovera, J., Murchison, C. & Bourdette, D. Sep 1 2016 In : Multiple Sclerosis and Related Disorders. 9, p. 80-90 11 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Randomized Controlled Trials
Fats
Diet
Fatigue
2 Citations

Omega-3 fatty acids for depression in multiple sclerosis: A randomized pilot study

Shinto, L., Marracci, G., Mohr, D. C., Bumgarner, L., Murchison, C., Senders, A. & Bourdette, D. Jan 1 2016 In : PLoS One. 11, 1, e0147195

Research output: Research - peer-reviewArticle

Omega-3 Fatty Acids
Multiple Sclerosis
Depression
sclerosis
omega-3 fatty acids
5 Citations
Patient Harm
Health Insurance
Multiple Sclerosis
Decision Making
Therapeutics
6 Citations

Spatio-temporal patterns of demyelination and remyelination in the cuprizone mouse model

Tagge, I., O'Connor, A., Chaudhary, P., Pollaro, J., Berlow, Y., Chalupsky, M., Bourdette, D., Woltjer, R., Johnson, M. & Rooney, W. Apr 1 2016 In : PLoS One. 11, 4, e0152480

Research output: Research - peer-reviewArticle

animal models
brain
Cuprizone
Demyelinating Diseases
mice
14 Citations

The contemporary spectrum of multiple sclerosis misdiagnosis

Solomon, A. J. , Bourdette, D. N. , Cross, A. H. , Applebee, A. , Skidd, P. M. , Howard, D. B. , Spain, R. I. , Cameron, M. H. , Kim, E. , Mass, M. K. , Yadav, V. , Whitham, R. H. , Longbrake, E. E. , Naismith, R. T. , Wu, G. F. , Parks, B. J. , Wingerchuk, D. M. , Rabin, B. L. , Toledano, M. , Tobin, W. O. & 4 others Kantarci, O. H., Carter, J. L., Keegan, B. M. & Weinshenker, B. G. Sep 27 2016 In : Neurology. 87, 13, p. 1393-1399 7 p.

Research output: Research - peer-reviewArticle

Diagnostic Errors
Multiple Sclerosis
Neurologic Manifestations
Therapeutics
Neuromyelitis Optica
2015

Author response

Hartung, D. M., Bourdette, D. N., Ahmed, S. & Whitham, R. H. Nov 10 2015 In : Neurology. 85, 19, p. 1728 1 p.

Research output: Research - peer-reviewArticle

Drug Industry
Immunologic Factors
Immunosuppressive Agents
Multiple Sclerosis
Tumor Necrosis Factor-alpha

Author response

Hartung, D. M., Bourdette, D. N. & Whitham, R. H. Nov 10 2015 In : Neurology. 85, 19, p. 1727 1 p.

Research output: Research - peer-reviewArticle

Drug Industry
Immunologic Factors
Immunosuppressive Agents
Multiple Sclerosis
Tumor Necrosis Factor-alpha
5 Citations

Cognitive Impairment and Community Integration Outcomes in Individuals Living With Multiple Sclerosis

Hughes, A. J., Hartoonian, N., Parmenter, B., Haselkorn, J. K., Lovera, J. F., Bourdette, D. & Turner, A. P. Nov 1 2015 In : Archives of Physical Medicine and Rehabilitation. 96, 11, p. 1973-1979 7 p.

Research output: Research - peer-reviewArticle

Community Integration
Multiple Sclerosis
Cognitive Dysfunction
Surveys and Questionnaires
Ginkgo biloba
5 Citations
Immunosuppressive Agents
Health Care Costs
Multiple Sclerosis
Glatiramer Acetate
Health Care Costs
Multiple Sclerosis
Glatiramer Acetate
9 Citations
Multiple Sclerosis
Fear
Statistical Factor Analysis
Logistic Models
Odds Ratio
2 Citations

Lipoic acid reduces inflammation in a mouse focal cortical experimental autoimmune encephalomyelitis model

Chaudhary, P., Marracci, G., Galipeau, D., Pocius, E., Morris, B. & Bourdette, D. Dec 15 2015 In : Journal of Neuroimmunology. 289, p. 68-74 7 p.

Research output: Research - peer-reviewArticle

Thioctic Acid
Autoimmune Experimental Encephalomyelitis
Inflammation
Galectin 3
Brain
9 Citations
Brain Mapping
Neuroimaging
Water
Brain
Multiple Sclerosis
1 Citations

Medications are associated with falls in people with multiple sclerosis

Cameron, M. H., Karstens, L., Hoang, P., Bourdette, D. & Lord, S. 2015 In : International Journal of MS Care. 17, 5, p. 207-214 8 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Therapeutics
Accidental Falls
Comorbidity
Logistic Models

Natalizumab to fingolimod: Questions answered, unanswered, and unasked

Stüve, O. & Bourdette, D. Jul 7 2015 In : Neurology. 85, 1, p. 14-15 2 p.

Research output: Research - peer-reviewArticle

Propylene Glycols
Drug Substitution
Antibodies, Monoclonal, Humanized
Relapsing-Remitting Multiple Sclerosis
Sphingosine
8 Citations

Polyphenon E, non-futile at neuroprotection in multiple sclerosis but unpredictably hepatotoxic: Phase I single group and phase II randomized placebo-controlled studies

Lovera, J., Ramos, A., Devier, D., Garrison, V., Kovner, B., Reza, T., Koop, D., Rooney, W., Foundas, A. & Bourdette, D. Nov 15 2015 In : Journal of the neurological sciences. 358, 1-2, p. 46-52 7 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Placebos
polyphenon E
Neuroprotection
epigallocatechin gallate
1 Citations

The cost of multiple sclerosis drugs in the US and the pharmaceutical industry: Too big to fail?

Tischner, J. R., Hartung, D. M., Bourdette, D. N., Whitham, R. H., Rittenhouse, B. E. & Ahmed, S. Nov 10 2015 In : Neurology. 85, 19, p. 1727-1728 2 p.

Research output: Research - peer-reviewArticle

Drug Industry
Immunologic Factors
Immunosuppressive Agents
Multiple Sclerosis
Tumor Necrosis Factor-alpha
59 Citations

The cost of multiple sclerosis drugs in the US and the pharmaceutical industry

Hartung, D. M., Bourdette, D. N., Ahmed, S. M. & Whitham, R. H. May 26 2015 In : Neurology. 84, 21, p. 2185-2192 8 p.

Research output: Research - peer-reviewArticle

Drug Industry
Multiple Sclerosis
Costs and Cost Analysis
Pharmaceutical Preparations
Therapeutics

The use of flow cytometry to assess a novel drug efficacy in multiple sclerosis

Benedek, G., Meza-Romero, R., Bourdette, D. & Vandenbark, A. A. 2015 In : Metabolic Brain Disease. 30, 4, p. 877-884 8 p., A002

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Flow Cytometry
Pharmaceutical Preparations
Flow cytometry
Disease Progression
2014
2 Citations

Alemtuzumab and multiple sclerosis: Is it safe?

Bourdette, D. Jul 1 2014 In : Neurology. 83, 1, p. 17-18 2 p.

Research output: Research - peer-reviewArticle

Antibodies, Monoclonal, Humanized
Multiple Sclerosis
alemtuzumab
67 Citations

A randomized placebo-controlled pilot trial of omega-3 fatty acids and alpha lipoic acid in Alzheimer's disease

Shinto, L., Quinn, J., Montine, T., Dodge, H. H., Woodward, W., Baldauf-Wagner, S., Waichunas, D., Bumgarner, L., Bourdette, D., Silbert, L. & Kaye, J. 2014 In : Journal of Alzheimer's Disease. 38, 1, p. 111-120 10 p.

Research output: Research - peer-reviewArticle

Thioctic Acid
Omega-3 Fatty Acids
Alzheimer Disease
Placebos
Activities of Daily Living

Author response

Yadav, V., Bever, C., Bowen, J., Bowling, A., Weinstock-Guttman, B., Cameron, M., Bourdette, D., Gronseth, G. S. & Narayanaswami, P. Oct 1 2014 In : Neurology. 83, 16, p. 1485-1486 2 p.

Research output: Research - peer-reviewArticle

Authors respond

Klein, E. & Bourdette, D. Feb 2014 In : Neurology: Clinical Practice. 4, 1, p. 3 1 p.

Research output: Research - peer-reviewArticle

4 Citations

BCG vaccine for clinically isolated syndrome and MS: Infections and protective immunity

Bourdette, D. & Naismith, R. T. Jan 7 2014 In : Neurology. 82, 1, p. 15-16 2 p.

Research output: Research - peer-reviewArticle

Infection
Immunity
Vaccine
Syndrome
19 Citations
Gait
Multiple Sclerosis
Walking Speed
Walking
Longitudinal Studies

Does interferon beta-1a impact pure-tone hearing sensitivity among individuals with multiple sclerosis?

Lewis, M. S., McMillan, G. P., Hutter, M., Folmer, R. L., Wilmington, D., Casiana, L., Fitzpatrick, M., Lilly, D. J., Bourdette, D., Overs, S., Cameron, M. & Fausti, S. Dec 1 2014 In : Journal of Neuroscience Nursing. 46, 6, p. 351-360 10 p.

Research output: Research - peer-reviewArticle

Hearing
Multiple Sclerosis
Interferon beta-1a
Therapeutics
Interferons
15 Citations

Falls in people with multiple sclerosis compared with falls in healthy controls

Mazumder, R., Murchison, C., Bourdette, D. & Cameron, M. Sep 25 2014 In : PLoS One. 9, 9, e107620

Research output: Research - peer-reviewArticle

Multiple Sclerosis
sclerosis
gender
Wounds and Injuries
Health

Microbial DNA testing for inflammatory diseases of the brain of uncertain etiology

Takahashi, C., Mass, M., Hamilton, B., Humayun Guletkin, S. & Bourdette, D. 2014 In : Neurology: Clinical Practice. 4, 3, p. 192-198 7 p.

Research output: Research - peer-reviewArticle

Brain Diseases
DNA
Neurologists
Mycoses
Bacterial Infections
2 Citations
Minocycline
Vertebral Artery
Spinal Cord Diseases
Vasculitis
1 Citations

New treatments for multiple sclerosis: At what long-term risk?

Cameron, M. H. & Bourdette, D. Mar 2014 In : The Lancet Neurology. 13, 3, p. 235-237 3 p.

Research output: Research - peer-reviewArticle

Cladribine
Immunosuppressive Agents
Multiple Sclerosis
Disease Progression
11 Citations
Mindfulness
Multiple Sclerosis
Health
Quality of Life
Psychological Resilience
10 Citations

Reducing survey burden: Feasibility and validity of PROMIS measures in multiple sclerosis

Senders, A., Hanes, D., Bourdette, D., Whitham, R. & Shinto, L. 2014 In : Multiple Sclerosis. 20, 8, p. 1102-1111 10 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Surveys and Questionnaires
Patient Reported Outcome Measures
Research
Statistical Factor Analysis
10 Citations

Remyelination and multiple sclerosis: therapeutic approaches and challenges

Hartley, M. D., Altowaijri, G. & Bourdette, D. Oct 1 2014 In : Current Neurology and Neuroscience Reports. 14, 10, p. 485 1 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Therapeutics
Demyelinating Diseases
Oligodendroglia
Axons
Headache
Magnetic Resonance Imaging
Brain
52 Citations

Summary of evidence-based guideline: Complementary and alternative medicine in multiple sclerosis: Report of the Guideline Development Subcommittee of the American Academy of Neurology

Yadav, V., Bever, C., Bowen, J., Bowling, A., Weinstock-Guttman, B., Cameron, M., Bourdette, D., Gronseth, G. S. & Narayanaswami, P. Mar 25 2014 In : Neurology. 82, 12, p. 1083-1092 10 p.

Research output: Research - peer-reviewArticle

Clinicians
Summary
Multiple Sclerosis
Complementary and Alternative Medicine
Complementary Therapies
1 Citations

Venous angioplasty for "CCSVI" in multiple sclerosis: Ending a therapeutic misadventure

Bourdette, D. N. & Cohen, J. A. Jul 29 2014 In : Neurology. 83, 5, p. 388-389 2 p.

Research output: Research - peer-reviewArticle

Venous Insufficiency
Angioplasty
Multiple Sclerosis
Therapeutics
2013
8 Citations
Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Autonomic Nervous System Diseases
13 Citations

Autoantibodies and Sjogren's Syndrome in Multiple Sclerosis, a Reappraisal

Solomon, A. J., Hills, W., Chen, Z., Rosenbaum, J., Bourdette, D. & Whitham, R. Jun 12 2013 In : PLoS One. 8, 6, e65385

Research output: Research - peer-reviewArticle

Sjogren's Syndrome
Autoantibodies
Multiple Sclerosis
autoantibodies
sclerosis