Research Output 1979 2017

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2017
1 Citations

Early Fever As a Predictor of Paroxysmal Sympathetic Hyperactivity in Traumatic Brain Injury

Hinson, H. E., Schreiber, M. A., Laurie, A. L., Baguley, I. J., Bourdette, D. & Ling, G. S. F. Jan 5 2017 (Accepted/In press) In : Journal of Head Trauma Rehabilitation.

Research output: Research - peer-reviewArticle

Fever
Traumatic Brain Injury
Vital Signs
Decerebrate State
Tachypnea
1 Citations

Ester-to-amide rearrangement of ethanolamine-derived prodrugs of sobetirome with increased blood-brain barrier penetration

Ferrara, S. J., Meinig, J. M., Placzek, A. T., Banerji, T., McTigue, P., Hartley, M. D., Sanford-Crane, H. S., Banerji, T., Bourdette, D. & Scanlan, T. S. May 15 2017 In : Bioorganic and Medicinal Chemistry. 25, 10, p. 2743-2753 11 p.

Research output: Research - peer-reviewArticle

Ethanolamine
Prodrugs
Blood-Brain Barrier
Amides
Esters

Lipoic acid in secondary progressive MS

Spain, R., Powers, K., Murchison, C., Heriza, E., Winges, K., Yadav, V., Cameron, M., Kim, E., Horak, F., Simon, J. & Bourdette, D. 2017 In : Neurology: Neuroimmunology and NeuroInflammation. 4, 5, 374

Research output: Research - peer-reviewArticle

Thioctic Acid
Brain
Atrophy
Placebos
Compliance

MIF and D-DT are potential disease severity modifiers in male MS subjects

Benedek, G. , Meza-Romero, R. , Jordan, K. , Zhang, Y. , Nguyen, H. , Kent, G. , Li, J. , Siu, E. , Frazer, J. , Piecychna, M. , Du, X. , Sreih, A. , Leng, L. , Wiedrick, J. , Caillier, S. J. , Offner, H. , Oksenberg, J. R. , Yadav, V. , Bourdette, D. , Bucala, R. & 1 others Vandenbark, A. A. Oct 3 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 40, p. E8421-E8429

Research output: Research - peer-reviewArticle

Multiple Sclerosis
dopachrome isomerase
Therapeutics
Macrophage Migration-Inhibitory Factors
Sex Factors
1 Citations

Sex-dependent treatment of chronic EAE with partial MHC class II constructs

Benedek, G., Chaudhary, P., Meza-Romero, R., Calkins, E., Kent, G., Offner, H., Bourdette, D. & Vandenbark, A. A. May 6 2017 In : Journal of Neuroinflammation. 14, 1, 100

Research output: Research - peer-reviewArticle

Autoimmune Experimental Encephalomyelitis
Multiple Sclerosis
Central Nervous System
Relapsing-Remitting Multiple Sclerosis
Estrogen Receptor alpha
1 Citations

Sleep and its associations with perceived and objective cognitive impairment in individuals with multiple sclerosis

Hughes, A. J., Parmenter, B. A., Haselkorn, J. K., Lovera, J. F., Bourdette, D., Boudreau, E., Cameron, M. H. & Turner, A. P. Aug 1 2017 In : Journal of Sleep Research. 26, 4, p. 428-435 8 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Sleep
Cognitive Dysfunction
Cognition
Sex Education
1 Citations

Trends and characteristics of US Medicare spending on repository corticotropin

Hartung, D. M., Johnston, K., Van Leuven, S., Deodhar, A., Cohen, D. M. & Bourdette, D. N. Nov 1 2017 In : JAMA Internal Medicine. 177, 11, p. 1680-1682 3 p.

Research output: Research - peer-reviewArticle

2016
3 Citations

Dimethyl fumarate activates the prostaglandin EP2 receptor and stimulates cAMP signaling in human peripheral blood mononuclear cells

Fiedler, S. E., Kerns, A. R., Tsang, C., Tsang, V., Bourdette, D. & Salinthone, S. Jun 17 2016 In : Biochemical and Biophysical Research Communications. 475, 1, p. 19-24 6 p.

Research output: Research - peer-reviewArticle

Prostaglandin Receptors
Cyclic AMP
Blood Cells
Dimethyl Fumarate
Prostaglandins
3 Citations

Immunopathology of Japanese macaque encephalomyelitis is similar to multiple sclerosis

Blair, T. C., Manoharan, M., Rawlings-Rhea, S. D., Tagge, I., Kohama, S. G., Hollister-Smith, J., Ferguson, B., Woltjer, R. L., Frederick, M. C., Pollaro, J., Rooney, W. D., Sherman, L. S., Bourdette, D. N. & Wong, S. W. Feb 15 2016 In : Journal of Neuroimmunology. 291, p. 1-10 10 p.

Research output: Research - peer-reviewArticle

Encephalomyelitis
Macaca
Multiple Sclerosis
Central Nervous System
T-Lymphocytes
4 Citations

Low-fat, plant-based diet in multiple sclerosis: A randomized controlled trial

Yadav, V., Marracci, G., Kim, E., Spain, R., Cameron, M., Overs, S., Riddehough, A., Li, D. K. B., McDougall, J., Lovera, J., Murchison, C. & Bourdette, D. Sep 1 2016 In : Multiple Sclerosis and Related Disorders. 9, p. 80-90 11 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Randomized Controlled Trials
Fats
Diet
Fatigue
1 Citations

Omega-3 fatty acids for depression in multiple sclerosis: A randomized pilot study

Shinto, L., Marracci, G., Mohr, D. C., Bumgarner, L., Murchison, C., Senders, A. & Bourdette, D. Jan 1 2016 In : PLoS One. 11, 1, e0147195

Research output: Research - peer-reviewArticle

Omega-3 Fatty Acids
Multiple Sclerosis
Depression
sclerosis
omega-3 fatty acids
4 Citations
Patient Harm
Health Insurance
Multiple Sclerosis
Decision Making
Therapeutics
4 Citations

Spatio-temporal patterns of demyelination and remyelination in the cuprizone mouse model

Tagge, I., O'Connor, A., Chaudhary, P., Pollaro, J., Berlow, Y., Chalupsky, M., Bourdette, D., Woltjer, R., Johnson, M. & Rooney, W. Apr 1 2016 In : PLoS One. 11, 4, e0152480

Research output: Research - peer-reviewArticle

animal models
brain
Cuprizone
Demyelinating Diseases
mice
10 Citations

The contemporary spectrum of multiple sclerosis misdiagnosis

Solomon, A. J. , Bourdette, D. N. , Cross, A. H. , Applebee, A. , Skidd, P. M. , Howard, D. B. , Spain, R. I. , Cameron, M. H. , Kim, E. , Mass, M. K. , Yadav, V. , Whitham, R. H. , Longbrake, E. E. , Naismith, R. T. , Wu, G. F. , Parks, B. J. , Wingerchuk, D. M. , Rabin, B. L. , Toledano, M. , Tobin, W. O. & 4 others Kantarci, O. H., Carter, J. L., Keegan, B. M. & Weinshenker, B. G. Sep 27 2016 In : Neurology. 87, 13, p. 1393-1399 7 p.

Research output: Research - peer-reviewArticle

Diagnostic Errors
Multiple Sclerosis
Neurologic Manifestations
Therapeutics
Neuromyelitis Optica
2015

Author response

Hartung, D. M., Bourdette, D. N., Ahmed, S. & Whitham, R. H. Nov 10 2015 In : Neurology. 85, 19, p. 1728 1 p.

Research output: Research - peer-reviewArticle

Author response

Hartung, D. M., Bourdette, D. N. & Whitham, R. H. Nov 10 2015 In : Neurology. 85, 19, p. 1727 1 p.

Research output: Research - peer-reviewArticle

5 Citations

Cognitive Impairment and Community Integration Outcomes in Individuals Living With Multiple Sclerosis

Hughes, A. J., Hartoonian, N., Parmenter, B., Haselkorn, J. K., Lovera, J. F., Bourdette, D. & Turner, A. P. Nov 1 2015 In : Archives of Physical Medicine and Rehabilitation. 96, 11, p. 1973-1979 7 p.

Research output: Research - peer-reviewArticle

Community Integration
Multiple Sclerosis
Cognitive Dysfunction
Surveys and Questionnaires
Ginkgo biloba
3 Citations
9 Citations
Multiple Sclerosis
Fear
Statistical Factor Analysis
Logistic Models
Odds Ratio
2 Citations

Lipoic acid reduces inflammation in a mouse focal cortical experimental autoimmune encephalomyelitis model

Chaudhary, P., Marracci, G., Galipeau, D., Pocius, E., Morris, B. & Bourdette, D. Dec 15 2015 In : Journal of Neuroimmunology. 289, p. 68-74 7 p.

Research output: Research - peer-reviewArticle

Thioctic Acid
Autoimmune Experimental Encephalomyelitis
Inflammation
Galectin 3
Brain
7 Citations
Brain Mapping
Neuroimaging
Water
Brain
Multiple Sclerosis
1 Citations

Medications are associated with falls in people with multiple sclerosis

Cameron, M. H., Karstens, L., Hoang, P., Bourdette, D. & Lord, S. 2015 In : International Journal of MS Care. 17, 5, p. 207-214 8 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Therapeutics
Accidental Falls
Comorbidity
Logistic Models

Natalizumab to fingolimod: Questions answered, unanswered, and unasked

Stüve, O. & Bourdette, D. Jul 7 2015 In : Neurology. 85, 1, p. 14-15 2 p.

Research output: Research - peer-reviewArticle

8 Citations

Polyphenon E, non-futile at neuroprotection in multiple sclerosis but unpredictably hepatotoxic: Phase I single group and phase II randomized placebo-controlled studies

Lovera, J., Ramos, A., Devier, D., Garrison, V., Kovner, B., Reza, T., Koop, D., Rooney, W., Foundas, A. & Bourdette, D. Nov 15 2015 In : Journal of the neurological sciences. 358, 1-2, p. 46-52 7 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Placebos
polyphenon E
Neuroprotection
epigallocatechin gallate
57 Citations

The cost of multiple sclerosis drugs in the US and the pharmaceutical industry

Hartung, D. M., Bourdette, D. N., Ahmed, S. M. & Whitham, R. H. May 26 2015 In : Neurology. 84, 21, p. 2185-2192 8 p.

Research output: Research - peer-reviewArticle

Drug Industry
Multiple Sclerosis
Costs and Cost Analysis
Pharmaceutical Preparations
Therapeutics
1 Citations

The cost of multiple sclerosis drugs in the US and the pharmaceutical industry: Too big to fail?

Tischner, J. R., Hartung, D. M., Bourdette, D. N., Whitham, R. H., Rittenhouse, B. E. & Ahmed, S. Nov 10 2015 In : Neurology. 85, 19, p. 1727-1728 2 p.

Research output: Research - peer-reviewArticle

The use of flow cytometry to assess a novel drug efficacy in multiple sclerosis

Benedek, G., Meza-Romero, R., Bourdette, D. & Vandenbark, A. A. 2015 In : Metabolic Brain Disease. 30, 4, p. 877-884 8 p., A002

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Flow Cytometry
Pharmaceutical Preparations
Flow cytometry
Disease Progression
2014
2 Citations

Alemtuzumab and multiple sclerosis: Is it safe?

Bourdette, D. Jul 1 2014 In : Neurology. 83, 1, p. 17-18 2 p.

Research output: Research - peer-reviewArticle

66 Citations

A randomized placebo-controlled pilot trial of omega-3 fatty acids and alpha lipoic acid in Alzheimer's disease

Shinto, L., Quinn, J., Montine, T., Dodge, H. H., Woodward, W., Baldauf-Wagner, S., Waichunas, D., Bumgarner, L., Bourdette, D., Silbert, L. & Kaye, J. 2014 In : Journal of Alzheimer's Disease. 38, 1, p. 111-120 10 p.

Research output: Research - peer-reviewArticle

Thioctic Acid
Omega-3 Fatty Acids
Alzheimer Disease
Placebos
Activities of Daily Living

Author response

Yadav, V., Bever, C., Bowen, J., Bowling, A., Weinstock-Guttman, B., Cameron, M., Bourdette, D., Gronseth, G. S. & Narayanaswami, P. Oct 1 2014 In : Neurology. 83, 16, p. 1485-1486 2 p.

Research output: Research - peer-reviewArticle

Authors respond

Klein, E. & Bourdette, D. Feb 2014 In : Neurology: Clinical Practice. 4, 1, p. 3 1 p.

Research output: Research - peer-reviewArticle

4 Citations

BCG vaccine for clinically isolated syndrome and MS: Infections and protective immunity

Bourdette, D. & Naismith, R. T. Jan 7 2014 In : Neurology. 82, 1, p. 15-16 2 p.

Research output: Research - peer-reviewArticle

18 Citations
Gait
Multiple Sclerosis
Walking Speed
Walking
Longitudinal Studies

Does interferon beta-1a impact pure-tone hearing sensitivity among individuals with multiple sclerosis?

Lewis, M. S., McMillan, G. P., Hutter, M., Folmer, R. L., Wilmington, D., Casiana, L., Fitzpatrick, M., Lilly, D. J., Bourdette, D., Overs, S., Cameron, M. & Fausti, S. Dec 1 2014 In : Journal of Neuroscience Nursing. 46, 6, p. 351-360 10 p.

Research output: Research - peer-reviewArticle

Hearing
Multiple Sclerosis
Interferon beta-1a
Therapeutics
Interferons
14 Citations

Falls in people with multiple sclerosis compared with falls in healthy controls

Mazumder, R., Murchison, C., Bourdette, D. & Cameron, M. Sep 25 2014 In : PLoS One. 9, 9, e107620

Research output: Research - peer-reviewArticle

Multiple Sclerosis
sclerosis
gender
Wounds and Injuries
Health

Microbial DNA testing for inflammatory diseases of the brain of uncertain etiology

Takahashi, C., Mass, M., Hamilton, B., Humayun Guletkin, S. & Bourdette, D. 2014 In : Neurology: Clinical Practice. 4, 3, p. 192-198 7 p.

Research output: Research - peer-reviewArticle

Brain Diseases
DNA
Neurologists
Mycoses
Bacterial Infections
2 Citations
1 Citations

New treatments for multiple sclerosis: At what long-term risk?

Cameron, M. H. & Bourdette, D. Mar 2014 In : The Lancet Neurology. 13, 3, p. 235-237 3 p.

Research output: Research - peer-reviewArticle

10 Citations
Mindfulness
Multiple Sclerosis
Health
Quality of Life
Psychological Resilience
10 Citations

Reducing survey burden: Feasibility and validity of PROMIS measures in multiple sclerosis

Senders, A., Hanes, D., Bourdette, D., Whitham, R. & Shinto, L. 2014 In : Multiple Sclerosis. 20, 8, p. 1102-1111 10 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Surveys and Questionnaires
Patient Reported Outcome Measures
Research
Statistical Factor Analysis
9 Citations

Remyelination and multiple sclerosis: therapeutic approaches and challenges

Hartley, M. D., Altowaijri, G. & Bourdette, D. Oct 1 2014 In : Current Neurology and Neuroscience Reports. 14, 10, p. 485 1 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Therapeutics
Demyelinating Diseases
Oligodendroglia
Axons
50 Citations

Summary of evidence-based guideline: Complementary and alternative medicine in multiple sclerosis: Report of the Guideline Development Subcommittee of the American Academy of Neurology

Yadav, V., Bever, C., Bowen, J., Bowling, A., Weinstock-Guttman, B., Cameron, M., Bourdette, D., Gronseth, G. S. & Narayanaswami, P. Mar 25 2014 In : Neurology. 82, 12, p. 1083-1092 10 p.

Research output: Research - peer-reviewArticle

Clinicians
Summary
Multiple Sclerosis
Complementary and Alternative Medicine
Complementary Therapies
1 Citations

Venous angioplasty for "CCSVI" in multiple sclerosis: Ending a therapeutic misadventure

Bourdette, D. N. & Cohen, J. A. Jul 29 2014 In : Neurology. 83, 5, p. 388-389 2 p.

Research output: Research - peer-reviewArticle

2013
8 Citations
12 Citations

Autoantibodies and Sjogren's Syndrome in Multiple Sclerosis, a Reappraisal

Solomon, A. J., Hills, W., Chen, Z., Rosenbaum, J., Bourdette, D. & Whitham, R. Jun 12 2013 In : PLoS One. 8, 6, e65385

Research output: Research - peer-reviewArticle

Sjogren's Syndrome
Autoantibodies
Multiple Sclerosis
autoantibodies
sclerosis
30 Citations

Mitochondrial dysfunction and neurodegeneration in multiple sclerosis

Su, K., Bourdette, D. & Forte, M. 2013 In : Frontiers in Physiology. 4 JUL, Article 169

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Plague
Demyelinating Diseases
Immunosuppressive Agents
Oxidation-Reduction
22 Citations

Partial MHC class II constructs inhibit MIF/CD74 binding and downstream effects

Benedek, G., Meza-Romero, R., Andrew, S., Leng, L., Burrows, G. G., Bourdette, D., Offner, H., Bucala, R. & Vandenbark, A. A. Apr 2013 In : European Journal of Immunology. 43, 5, p. 1309-1321 13 p.

Research output: Research - peer-reviewArticle

Down-Regulation
T-Cell Antigen Receptor
Multiple Sclerosis
Monocytes
Immune System
7 Citations

People with multiple sclerosis use many fall prevention strategies but still fall frequently

Cameron, M. H., Asano, M., Bourdette, D. & Finlayson, M. L. Aug 2013 In : Archives of Physical Medicine and Rehabilitation. 94, 8, p. 1562-1566 5 p.

Research output: Research - peer-reviewArticle

Multiple Sclerosis
Surveys and Questionnaires
Delivery of Health Care
Veterans
Observational Studies