David Morton

Kanost, M. R., Arrese, E. L., Cao, X., Chen, Y. R., Chellapilla, S., Goldsmith, M. R., Grosse-Wilde, E., Heckel, D. G., Herndon, N., Jiang, H., Papanicolaou, A., Qu, J., Soulages, J. L., Vogel, H., Walters, J., Waterhouse, R. M., Ahn, S. J., Almeida, F. C., An, C., Aqrawi, P., & 94 othersBretschneider, A., Bryant, W. B., Bucks, S., Chao, H., Chevignon, G., Christen, J. M., Clarke, D. F., Dittmer, N. T., Ferguson, L. C. F., Garavelou, S., Gordon, K. H. J., Gunaratna, R. T., Han, Y., Hauser, F., He, Y., Heidel-Fischer, H., Hirsh, A., Hu, Y., Jiang, H., Kalra, D., Klinner, C., König, C., Kovar, C., Kroll, A. R., Kuwar, S. S., Lee, S. L., Lehman, R., Li, K., Li, Z., Liang, H., Lovelace, S., Lu, Z., Mansfield, J. H., McCulloch, K. J., Mathew, T., Morton, B., Muzny, D. M., Neunemann, D., Ongeri, F., Pauchet, Y., Pu, L. L., Pyrousis, I., Rao, X. J., Redding, A., Roesel, C., Sanchez-Gracia, A., Schaack, S., Shukla, A., Tetreau, G., Wang, Y., Xiong, G. H., Traut, W., Walsh, T. K., Worley, K. C., Wu, D., Wu, W., Wu, Y. Q., Zhang, X., Zou, Z., Zucker, H., Briscoe, A. D., Burmester, T., Clem, R. J., Feyereisen, R., Grimmelikhuijzen, C. J. P., Hamodrakas, S. J., Hansson, B. S., Huguet, E., Jermiin, L. S., Lan, Q., Lehman, H. K., Lorenzen, M., Merzendorfer, H., Michalopoulos, I., Morton, D. B., Muthukrishnan, S., Oakeshott, J. G., Palmer, W., Park, Y., Passarelli, A. L., Rozas, J., Schwartz, L. M., Smith, W., Southgate, A., Vilcinskas, A., Vogt, R., Wang, P., Werren, J., Yu, X. Q., Zhou, J. J., Brown, S. J., Scherer, S. E., Richards, S. & Blissard, G. W., Sep 1 2016, In: Insect Biochemistry and Molecular Biology. 76, p. 118-147 30 p.

Research output: Contribution to journal › Article › peer-review

Open Access

128 Scopus citations

2015

Role for Rab10 in methamphetamine-induced behavior

Vanderwerf, S. M., Buck, D. C., Wilmarth, P. A., Sears, L. M., David, L. L., Morton, D. B. & Neve, K. A., Aug 20 2015, In: PloS one. 10, 8, e0136167.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2014

Motor neuron expression of the voltage-gated calcium channel cacophony restores locomotion defects in a Drosophila, TDP-43 loss of function model of ALS

Chang, J. C., Hazelett, D. J., Stewart, J. A. & Morton, D. B., Oct 10 2014, In: Brain research. 1584, p. 39-51 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

2013

Phosphodiesterase-8A binds to and regulates Raf-1 kinase

Brown, K. M., Day, J. P., Huston, E., Zimmermann, B., Hampel, K., Christian, F., Romano, D., Terhzaz, S., Lee, L. C. Y., Willis, M. J., Morton, D. B., Beavo, J. A., Shimizu-Albergine, M., Davies, S. A., Kolch, W., Houslay, M. D. & Baillie, G. S., Apr 16 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 16, p. E1533-E1542

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

2012

Comparison of parallel high-throughput RNA sequencing between knockout of TDP-43 and its overexpression reveals primarily nonreciprocal and nonoverlapping gene expression changes in the central nervous system of drosophila

Hazelett, D. J., Chang, J. C., Lakeland, D. L. & Morton, D. B., Jul 2012, In: G3: Genes, Genomes, Genetics. 2, 7, p. 789-802 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

2011

Behavioral responses to hypoxia and hyperoxia in Drosophila larvae molecular and neuronal sensors

Morton, D. B., 2011, In: Fly. 5, 2, p. 119-125 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Drosophila gustatory preference behaviors require the atypical soluble guanylyl cyclases

Vermehren-Schmaedick, A., Scudder, C., Timmermans, W. & Morton, D. B., Jul 2011, In: Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology. 197, 7, p. 717-727 11 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Response properties of visual neurons in the turtle nucleus isthmi

Saha, D., Morton, D., Ariel, M. & Wessel, R., Feb 2011, In: Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology. 197, 2, p. 153-165 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

2010

Behavioral responses to hypoxia in drosophila larvae are mediated by atypical soluble guanylyl cyclases

Vermehren-Schmaedick, A., Ainsley, J. A., Johnson, W. A., Davies, S. A. & Morton, D. B., Sep 2010, In: Genetics. 186, 1, p. 183-196 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

Infertility and male mating behavior deficits associated with Pde1c in Drosophila melanogaster

Morton, D. B., Clemens-Grisham, R., Hazelett, D. J. & Vermehren-Schmaedick, A., Sep 2010, In: Genetics. 186, 1, p. 159-165 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2009

Neurons Detect Increases and Decreases in Oxygen Levels Using Distinct Guanylate Cyclases

Zimmer, M., Gray, J. M., Pokala, N., Chang, A. J., Karow, D. S., Marletta, M. A., Hudson, M. L., Morton, D. B., Chronis, N. & Bargmann, C. I., Mar 26 2009, In: Neuron. 61, 6, p. 865-879 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

208 Scopus citations

2008

Synaptic transmission in neurons that express the Drosophila atypical soluble guanylyl cyclases, Gyc-89Da and Gyc-89Db, is necessary for the successful completion of larval and adult ecdysis

Morton, D. B., Stewart, J. A., Langlais, K. K., Clemens-Grisham, R. A. & Vermehren, A., May 2008, In: Journal of Experimental Biology. 211, 10, p. 1645-1656 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

2007

Soluble guanylyl cyclases in invertebrates: Targets for NO and O₂

Morton, D. B. & Vermehren, A., 2007, Nitric Oxide. Tota, B. & Trimmer, B. (eds.). p. 65-82 18 p. (Advances in Experimental Biology; vol. 1).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Open Access

7 Scopus citations

2006

Oxygen-sensitive guanylyl cyclases in insects and their potential roles in oxygen detection and in feeding behaviors

Vermehren, A., Langlais, K. K. & Morton, D. B., Apr 2006, In: Journal of Insect Physiology. 52, 4, p. 340-348 9 p.

Research output: Contribution to journal › Review article › peer-review

26 Scopus citations

2005

Comparison of the properties of the five soluble guanylyl cyclase subunits in Drosophila melanogaster

Morton, D. B., Langlais, K. K., Stewart, J. A. & Vermehren, A., Apr 19 2005, In: Journal of Insect Science. 5, p. 1-10 10 p., 12.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

2004

Atypical soluble guanylyl cyclases in Drosophila can function as molecular oxygen sensors

Morton, D. B., Dec 3 2004, In: Journal of Biological Chemistry. 279, 49, p. 50651-50653 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

Invertebrates yield a plethora of atypical guanylyl cyclases

Morton, D. B., Apr 2004, In: Molecular Neurobiology. 29, 2, p. 97-115 19 p.

Research output: Contribution to journal › Review article › peer-review

53 Scopus citations

Preliminary characterization of two atypical soluble guanylyl cyclases in the central and peripheral nervous system of Drosophila melanogaster

Langlais, K. K., Stewart, J. A. & Morton, D. B., Jun 2004, In: Journal of Experimental Biology. 207, 13, p. 2323-2338 16 p.

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

2003

MsGC-II, a receptor guanylyl cyclase isolated from the CNS of Manduca sexta that is inhibited by calcium

Morton, D. B. & Nighorn, A., Jan 2003, In: Journal of neurochemistry. 84, 2, p. 363-372 10 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

MsGC-β3 forms active homodimers and inactive heterodimers with NO-sensitive soluble guanylyl cyclase subunits

Morton, D. B. & Anderson, E. J., Mar 2003, In: Journal of Experimental Biology. 206, 6, p. 937-947 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

2002

Cellular signaling in eclosion hormone action

Morton, D. B. & Simpson, P. J., 2002, In: Journal of Insect Physiology. 48, 1, p. 1-13 13 p.

Research output: Contribution to journal › Short survey › peer-review

24 Scopus citations

Cyclic GMP regulation and function in insects

Morton, D. B. & Hudson, M. L., 2002, Advances in Insect Physiology. Academic Press Inc., p. 1-54 54 p. (Advances in Insect Physiology; vol. 29).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

28 Scopus citations

Nicotinic-acetylcholine receptors are functionally coupled to the nitric oxide/cGMP-pathway in insect neurons

Zayas, R. M., Qazi, S., Morton, D. B. & Trimmer, B. A., Oct 2002, In: Journal of neurochemistry. 83, 2, p. 421-431 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

40 Scopus citations

2001

The novel guanylyl cyclase MsGC-I is strongly expressed in higher-order neuropils in the brain of Manduca sexta

Nighorn, A., Simpson, P. J. & Morton, D. B., 2001, In: Journal of Experimental Biology. 204, 2, p. 305-314 10 p.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

2000

Identification of the cellular target for eclosion hormone in the abdominal transverse nerves of the tobacco hornworm, Manduca sexta

Hesterlee, S. & Morton, D. B., Aug 21 2000, In: Journal of Comparative Neurology. 424, 2, p. 339-355 17 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Neurons involved in nitric oxide-mediated cGMP signaling in the tobacco hornworm, Manduca sexta

Zayas, R. M., Qazi, S., Morton, D. B. & Trimmer, B. A., Apr 17 2000, In: Journal of Comparative Neurology. 419, 4, p. 422-438 17 p.

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

1999

Identification and characterization of a novel β subunit of soluble guanylyl cyclase that is active in the absence of a second subunit and is relatively insensitive to nitric oxide

Nighorn, A., Byrnes, K. A. & Morton, D. B., Jan 22 1999, In: Journal of Biological Chemistry. 274, 4, p. 2525-2531 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

50 Scopus citations

Identification of a novel guanylyl cyclase that is related to receptor guanylyl cyclases, but lacks extracellular and transmembrane domains

Simpson, P. J., Nighorn, A. & Morton, D. B., Feb 12 1999, In: Journal of Biological Chemistry. 274, 7, p. 4440-4446 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

Soluble guanylyl cyclases in Caenorhabditis elegans: NO is not the answer [1]

Morton, D. B., Hudson, M. L., Waters, E. & O'Shea, M., Aug 12 1999, In: Current Biology. 9, 15, p. R546-R547

Research output: Contribution to journal › Article › peer-review

Open Access

40 Scopus citations

1998

Norepinephrine increases cyclic GMP levels in cerebellar cells from neuronal nitric oxide synthase knockout mice

Morton, D. B. & Bredt, D. S., Jul 1998, In: Journal of neurochemistry. 71, 1, p. 440-443 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

The nitric oxide-cGMP pathway may mediate communication between sensory afferents and projection neurons in the antennal lobe of Manduca sexta

Nighorn, A., Gibson, N. J., Rivers, D. M., Hildebrand, J. G. & Morton, D. B., Sep 15 1998, In: Journal of Neuroscience. 18, 18, p. 7244-7255 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

112 Scopus citations

1997

Eclosion hormone action on the nervous system. Intracellular messengers and sites of action

Morton, D. B., 1997, In: Annals of the New York Academy of Sciences. 814, p. 40-52 13 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Up- and downregulation of esr20, an ecdysteroid-regulated gene expressed in the tracheae of Manduca sexta

Mészáros, M. & Morton, D. B., 1997, In: Archives of insect biochemistry and physiology. 34, 2, p. 159-174 16 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

1996

Comparison of the expression patterns of five developmentally regulated genes in Manduca sexta and their regulation by 20-hydroxyecdysone in vitro

Mészáros, M. & Morton, D. B., Jul 1996, In: Journal of Experimental Biology. 199, 7, p. 1555-1561 7 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Expression of a developmentally regulated gene, Mng10, in identified neurosecretory cells in the CNS of Manduca sexta

Mészáros, M. & Morton, D. B., Jul 1996, In: Journal of Neurobiology. 30, 3, p. 349-358 10 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Identification of a developmentally regulated gene, esr16, in the tracheal epithelium of Manduca sexta, with homology to a protein from human epididymis

Mészáros, M. & Morton, D. B., 1996, In: Insect Biochemistry and Molecular Biology. 26, 1, p. 7-11 5 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Insect physiology: The emerging story of ecdysis

Hesterlee, S. & Morton, D. B., 1996, In: Current Biology. 6, 6, p. 648-650 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Neuropeptide-stimulated cyclic guanosine monophosphate immunoreactivity in the neurosecretory terminals of a neurohemal organ

Morton, D. B., Mar 1996, In: Journal of Neurobiology. 29, 3, p. 341-353 13 p.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Subtractive hybridization strategy using paramagnetic oligo(dT) beads and PCR

Mészáros, M. & Morton, D. B., Mar 1996, In: BioTechniques. 20, 3, p. 413-419 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

1995

Eclosion hormone-stimulated cGMP levels in the central nervous system of Manduca sexta: inhibition by lipid metabolism blockers, increase in inositol(1,4,5)trisphosphate and further evidence against the involvement of nitric oxide

Morton, D. B. & Simpson, P. J., Dec 1995, In: Journal of Comparative Physiology B. 165, 6, p. 417-427 11 p.

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Effect of cycloheximide on eclosion hormone sensitivity and the developmental appearance of the eclosion hormone and cGMP regulated phosphoproteins in the CNS of the tobacco hornworm, manduca sexta

Morton, D. B. & Truman, J. W., 1995, In: Journal of Receptors and Signal Transduction. 15, 5, p. 773-786 14 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Remodeling of the insect nervous system

Levine, R. B., Morton, D. B. & Restifo, L. L., Feb 1995, In: Current Opinion in Neurobiology. 5, 1, p. 28-35 8 p.

Research output: Contribution to journal › Article › peer-review

112 Scopus citations

1994

Isolation and partial characterization of a gene from trachea of Manduca sexta that requires and is negatively regulated by ecdysteroids

Mészáros, M. & Morton, D. B., Apr 1994, In: Developmental Biology. 162, 2, p. 618-630 13 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Spatiotemporal pattern of expression of tenascin‐like molecules in a developing insect olfactory system

Krull, C. E., Morton, D. B., Faissner, A., Schachner, M. & Tolbert, L. P., May 1994, In: Journal of Neurobiology. 25, 5, p. 515-534 20 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

David Morton

Research output

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