• 5549 Citations
  • 40 h-Index
1986 …2020

Research output per year

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Research Output

2020

IL-5 exposure in utero increases lung nerve density and airway reactivity in adult offspring

Lebold, K. M., Drake, M. G., Hales-Beck, L. B., Fryer, A. D. & Jacoby, D. B., 2020, In : American journal of respiratory cell and molecular biology. 62, 4, p. 493-502 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Inflammatory mechanisms linking maternal and childhood asthma

Lebold, K. M., Jacoby, D. B. & Drake, M. G., Jul 1 2020, In : Journal of Leukocyte Biology. 108, 1, p. 113-121 9 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Optogenetic control of airway cholinergic neurons in vivo

Pincus, A. B., Adhikary, S., Lebold, K. M., Fryer, A. D. & Jacoby, D. B., 2020, In : American journal of respiratory cell and molecular biology. 62, 4, p. 423-429 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Organophosphorus pesticides induce cytokine release from differentiated human THP1 cells

Proskocil, B. J., Grodzki, A. C. G., Jacoby, D. B., Lein, P. J. & Fryer, A. D., 2019, In : American journal of respiratory cell and molecular biology. 61, 5, p. 620-630 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Eosinophil and airway nerve interactions in asthma

Drake, M., Lebold, K. M., Roth-Carter, Q. R., Pincus, A. B., Blum, E. D., Proskocil, B. J., Jacoby, D., Fryer, A. & Nie, Z. J., Jul 1 2018, In : Journal of Leukocyte Biology. 104, 1, p. 61-67 7 p.

Research output: Contribution to journalReview article

15 Scopus citations

Eosinophils increase airway sensory nerve density in mice and in human asthma

Drake, M., Scott, G. D., Blum, E. D., Lebold, K. M., Nie, Z. J., Lee, J. J., Fryer, A., Costello, R. W. & Jacoby, D., Sep 5 2018, In : Science Translational Medicine. 10, 457, aar8477.

Research output: Contribution to journalArticle

17 Scopus citations
2017

An official American thoracic society research statement: Current challenges facing research and therapeutic advances in airway remodeling

ATS Assembly on Respiratory Structure and Function, Jan 15 2017, In : American journal of respiratory and critical care medicine. 195, 2, p. e4-e19

Research output: Contribution to journalReview article

32 Scopus citations

In Memory and Celebration: Dr. James J. Lee

Rosenberg, H. F., Fryer, A., Munitz, A., Bochner, B. S., Jacoby, D., Levi-Schaffer, F., Gleich, G. J., Furuta, G. T., Rothenberg, M. E., Lacy, P., Fulkerson, P. C., Hogan, S. P., Ackerman, S. J. & Foster, P. S., Jul 1 2017, In : Clinical and Experimental Allergy. 47, 7, p. 980-981 2 p.

Research output: Contribution to journalLetter

6 Scopus citations
4 Scopus citations
2016

Human and mouse eosinophils have antiviral activity against parainfluenza virus

Drake, M., Bivins-Smith, E. R., Proskocil, B. J., Nie, Z. J., Scott, G. D., Lee, J. J., Lee, N. A., Fryer, A. & Jacoby, D., Sep 1 2016, In : American Journal of Respiratory Cell and Molecular Biology. 55, 3, p. 387-394 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Toll-Like Receptor 7-Targeted Therapy in Respiratory Disease

Lebold, K. M., Jacoby, D. B. & Drake, M. G., Mar 1 2016, In : Transfusion Medicine and Hemotherapy. 43, 2, p. 114-119 6 p.

Research output: Contribution to journalReview article

6 Scopus citations
2015

Eosinophil-dependent skin innervation and itching following contact toxicant exposure in mice

Lee, J. J., Protheroe, C. A., Luo, H., Ochkur, S. I., Scott, G. D., Zellner, K. R., Raish, R. J., Dahl, M. V., Vega, M. L., Conley, O., Condjella, R. M., Kloeber, J. A., Neely, J. L., Patel, Y. S., Maizer, P., Mazzolini, A., Fryer, A. D., Jacoby, N. W., Jacoby, D. B. & Lee, N. A., Feb 1 2015, In : Journal of Allergy and Clinical Immunology. 135, 2, p. 477-487.e1

Research output: Contribution to journalArticle

15 Scopus citations

The influence of sensitization on mechanisms of organophosphorus pesticide-induced airway hyperreactivity

Proskocil, B. J., Bruun, D. A., Garg, J. A., Villagomez, C. C., Jacoby, D. B., Lein, P. J. & Fryer, A. D., Nov 2015, In : American journal of respiratory cell and molecular biology. 53, 5, p. 738-747 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
2014
36 Scopus citations

Interactions of eosinophils with nerves

Roth-Carter, Q. R., Jacoby, D. B. & Nie, Z., 2014, Eosinophils: Methods and Protocols. Humana Press Inc., p. 215-229 15 p. (Methods in Molecular Biology; vol. 1178).

Research output: Chapter in Book/Report/Conference proceedingChapter

13 Scopus citations
24 Scopus citations
2013

Dual p38/JNK Mitogen Activated Protein Kinase Inhibitors Prevent Ozone-Induced Airway Hyperreactivity in Guinea Pigs

Verhein, K. C., Salituro, F. G., Ledeboer, M. W., Fryer, A. D. & Jacoby, D. B., Sep 18 2013, In : PloS one. 8, 9, e75351.

Research output: Contribution to journalArticle

6 Scopus citations

Eosinophils in Human Disease

Gelfand, E. W., Simon, D., Simon, H. U., Thomas, A., Busse, W. W., Nair, P., Gauvreau, G. M., Denburg, J. A., Bivins-Smith, E. R., Jacoby, D. B., Davis, B. P., Rothenberg, M. E., Khoury, P., Klion, A. D., Lotfi, R., Spada, N., Lotze, M. T., Schleimer, R. P., Kato, A., Kern, R. & 10 others, Lavigne, M. C., Eppihimer, M. J., Roufosse, F., Massart, A., Benghiat, F. S., Lemaitre, P., Le Moine, A., Krahn, M., Bartoli, M. & Levy, N., 2013, Eosinophils in Health and Disease. Elsevier Inc., p. 431-536 106 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs

Proskocil, B. J., Bruun, D. A., Jacoby, D. B., van Rooijen, N., Lein, P. J. & Fryer, A. D., 2013, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 304, 8, p. L519-L529

Research output: Contribution to journalArticle

20 Scopus citations
9 Scopus citations
12 Scopus citations

Toll-like receptor 7 rapidly relaxes human airways

Drake, M. G., Scott, G. D., Proskocil, B. J., Fryer, A. D., Jacoby, D. B. & Kaufman, E. H., Sep 15 2013, In : American journal of respiratory and critical care medicine. 188, 6, p. 664-672 9 p.

Research output: Contribution to journalArticle

29 Scopus citations
2012

Comment

Rynko, A. E. & Jacoby, D. B., Nov 1 2012, In : Neuromodulation. 15, 6, p. 535-536 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Muscarinic receptor agonists and antagonists: Effects on inflammation and immunity

Verbout, N. G. & Jacoby, D. B., Feb 10 2012, Muscarinic Receptors. Fryer, A. D., Nathanson, N. M. & Christopoulos, A. (eds.). p. 403-427 25 p. (Handbook of Experimental Pharmacology; vol. 208).

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations
38 Scopus citations

Preformed CD40L is stored in Th1, Th2, Th17, and T follicular helper cells as well as CD4 +8 - thymocytes and invariant NKT cells but not in Treg cells

Koguchi, Y., Buenafe, A. C., Thauland, T. J., Gardell, J. L., Bivins-Smith, E. R., Jacoby, D. B., Slifka, M. K. & Parker, D. C., Feb 21 2012, In : PloS one. 7, 2, e31296.

Research output: Contribution to journalArticle

26 Scopus citations

The therapeutic potential of toll-like receptor 7 stimulation in Asthma

Drake, M. G., Kaufman, E. H., Fryer, A. D. & Jacoby, D. B., Dec 4 2012, In : Inflammation and Allergy - Drug Targets. 11, 6, p. 484-491 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Upping the antedrug: Is a novel anti-inflammatory Toll-like receptor 7 agonist also a bronchodilator?

Kaufman, E. H. & Jacoby, D. B., May 1 2012, In : British Journal of Pharmacology. 166, 2, p. 569-572 4 p.

Research output: Contribution to journalReview article

5 Scopus citations

β2-Agonists Inhibit TNF-α-Induced ICAM-1 Expression in Human Airway Parasympathetic Neurons

Nie, Z., Fryer, A. D. & Jacoby, D. B., Sep 25 2012, In : PloS one. 7, 9, e44780.

Research output: Contribution to journalArticle

5 Scopus citations
2011

Eosinophils increase neuron branching in human and murine skin and in vitro

Foster, E. L., Simpson, E. L., Fredrikson, L. J., Lee, J. J., Lee, N. A., Fryer, A. D. & Jacoby, D. B., 2011, In : PloS one. 6, 7, e22029.

Research output: Contribution to journalArticle

48 Scopus citations

Role of TNF-α in virus-induced airway hyperresponsiveness and neuronal M 2 muscarinic receptor dysfunction

Nie, Z., Scott, G. D., Weis, P. D., Itakura, A., Fryer, A. D. & Jacoby, D. B., Sep 2011, In : British Journal of Pharmacology. 164, 2 B, p. 444-452 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
8 Scopus citations

Toll-like receptor 7 agonists are potent and rapid bronchodilators in guinea pigs

Kaufman, E. H., Fryer, A. D. & Jacoby, D. B., Feb 1 2011, In : Journal of Allergy and Clinical Immunology. 127, 2, p. 462-469 8 p.

Research output: Contribution to journalArticle

30 Scopus citations
2010

Human mucosal associated invariant T cells detect bacterially infected cells

Gold, M. C., Cerri, S., Smyk-Pearson, S., Cansler, M. E., Vogt, T. M., Delepine, J., Winata, E., Swarbrick, G. M., Chua, W. J., Yu, Y. Y. L., Lantz, O., Cook, M. S., Null, M. D., Jacoby, D. B., Harriff, M. J., Lewinsohn, D. A., Hansen, T. H. & Lewinsohn, D. M., Jun 2010, In : PLoS Biology. 8, 6

Research output: Contribution to journalArticle

357 Scopus citations
2009
16 Scopus citations
25 Scopus citations

Neural control of airway inflammation

Verhein, K. C., Fryer, A. D. & Jacoby, D. B., Oct 26 2009, In : Current Allergy and Asthma Reports. 9, 6, p. 484-490 7 p.

Research output: Contribution to journalReview article

21 Scopus citations
4 Scopus citations
2008

Antigen sensitization influences organophosphorus pesticide-induced airway hyperreactivity

Proskocil, B. J., Bruun, D. A., Lorton, J. K., Blensly, K. C., Jacoby, D. B., Lein, P. J. & Fryer, A. D., Mar 2008, In : Environmental health perspectives. 116, 3, p. 381-388 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Characterization of side population cells from human airway epithelium

Hackett, T. L., Shaheen, F., Johnson, A., Wadsworth, S., Pechkovsky, D. V., Jacoby, D. B., Kicic, A., Stick, S. M. & Knight, D. A., Oct 2008, In : Stem Cells. 26, 10, p. 2576-2585 10 p.

Research output: Contribution to journalArticle

100 Scopus citations

Cigarette smoke induces genetic instability in airway epithelial cells by suppressing FANCD2 expression

Hays, L. E., Zodrow, D. M., Yates, J. E., Deffebach, M. E., Jacoby, D. B., Olson, S. B., Pankow, J. F. & Bagby, G. C., May 20 2008, In : British Journal of Cancer. 98, 10, p. 1653-1661 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
22 Scopus citations
2007
24 Scopus citations

Expression and regulation of intercellular adhesion molecule-1 on airway parasympathetic nerves

Nie, Z., Nelson, C. S., Jacoby, D. B. & Fryer, A. D., Jun 1 2007, In : Journal of Allergy and Clinical Immunology. 119, 6, p. 1415-1422 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Intrapulmonary delivery of ricin at high dosage triggers a systemic inflammatory response and glomerular damage

Wong, J., Korcheva, V., Jacoby, D. B. & Magun, B., May 2007, In : American Journal of Pathology. 170, 5, p. 1497-1510 14 p.

Research output: Contribution to journalArticle

42 Scopus citations
36 Scopus citations