David Ellison

Professor

  • 8307 Citations
  • 49 h-Index
1982 …2021
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Research Output 1982 2020

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Article
2020

Potassium homeostasis and management of dyskalemia in kidney diseases: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Clase, C. M., Carrero, J. J., Ellison, D. H., Grams, M. E., Hemmelgarn, B. R., Jardine, M. J., Kovesdy, C. P., Kline, G. A., Lindner, G., Obrador, G. T., Palmer, B. F., Cheung, M., Wheeler, D. C., Winkelmayer, W. C., Pecoits-Filho, R., Ashuntantang, G. E., Bakker, S. J. L., Bakris, G. L., Bhandari, S., Burdmann, E. A. & 33 others, Campbell, K. L., Charytan, D. M., Clegg, D. J., Cuppari, L., Goldsmith, D., Hallan, S. I., He, J., Herzog, C. A., Hoenig, M. P., Hoorn, E. J., Leipziger, J. G., Leonberg-Yoo, A. K., Lerma, E. V., Lopez-Almaraz, J. E., Małyszko, J., Mann, J. F. E., Marklund, M., McDonough, A. A., Nagahama, M., Navaneethan, S. D., Pitt, B., Pochynyuk, O. M., Proença de Moraes, T., Rafique, Z., Robinson, B. M., Roger, S. D., Rossignol, P., Singer, A. J., Smyth, A., Sood, M. M., Walsh, M., Weir, M. R. & Wingo, C. S., Jan 2020, In : Kidney International. 97, 1, p. 42-61 20 p.

Research output: Contribution to journalArticle

Open Access
Kidney Diseases
Potassium
Homeostasis
Diet Therapy
Hyperkalemia
2019
2 Citations (Scopus)

Animal Models of Hypertension: A Scientific Statement From the American Heart Association

Lerman, L. O., Kurtz, T. W., Touyz, R. M., Ellison, D. H., Chade, A. R., Crowley, S. D., Mattson, D. L., Mullins, J. J., Osborn, J., Eirin, A., Reckelhoff, J. F., Iadecola, C. & Coffman, T. M., Jun 1 2019, In : Hypertension (Dallas, Tex. : 1979). 73, 6, p. e87-e120

Research output: Contribution to journalArticle

Open Access
Animal Models
Hypertension
Comorbidity
Chronic Disease
Research Design
2 Citations (Scopus)

Clinical pharmacology in diuretic use

Ellison, D., Aug 7 2019, In : Clinical Journal of the American Society of Nephrology. 14, 8, p. 1248-1257 10 p.

Research output: Contribution to journalArticle

Open Access
Cardio-Renal Syndrome
Kidney Tubules
Clinical Pharmacology
Diuresis
Nephrotic Syndrome
1 Citation (Scopus)

Kir4.1/Kir5.1 in the DCT plays a role in the regulation of renal K + excretion

Su, X. T., Ellison, D. & Wang, W. H., Mar 1 2019, In : American journal of physiology. Renal physiology. 316, 3, p. F582-F586

Research output: Contribution to journalArticle

Potassium
Member 1 Solute Carrier Family 12
Angiotensin Type 2 Receptor
Bradykinin B2 Receptors
Inwardly Rectifying Potassium Channel

Optical clearing and imaging of immunolabeled kidney tissue

Saritas, T., Puelles, V. G., Su, X. T., Ellison, D. & Kramann, R., Jul 1 2019, In : Journal of Visualized Experiments. 2019, 149, e60002.

Research output: Contribution to journalArticle

Optical Imaging
Antibodies
Tissue
Kidney
Imaging techniques
1 Citation (Scopus)

Patients with hypokalemia develop WNK bodies in the distal convoluted tubule of the kidney

Thomson, M. N., Schneider, W., Mutig, K., Ellison, D., Kettritz, R. & Bachmann, S., Feb 1 2019, In : American journal of physiology. Renal physiology. 316, 2, p. F292-F300

Research output: Contribution to journalArticle

Distal Kidney Tubule
Hypokalemia
Member 3 Solute Carrier Family 12
Phosphotransferases
Kidney

Renal-Tubule Epithelial Cell Nomenclature for Single-Cell RNA-Sequencing Studies

Chen, L., Clark, J. Z., Nelson, J. W., Kaissling, B., Ellison, D. & Knepper, M. A., Aug 1 2019, In : Journal of the American Society of Nephrology : JASN. 30, 8, p. 1358-1364 7 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Terminology
Epithelium
Epithelial Cells
Kidney
1 Citation (Scopus)

Salt-sensitive transcriptome of isolated kidney distal tubule cells

Swanson, E. A., Nelson, J. W., Jeng, S., Erspamer, K. J., Yang, C-L., McWeeney, S. & Ellison, D., Apr 1 2019, In : Physiological genomics. 51, 4, p. 125-135 11 p.

Research output: Contribution to journalArticle

Distal Kidney Tubule
Aldosterone
Transcriptome
Salts
Diet
1 Citation (Scopus)

Separate and interacting effects of the endogenous circadian system and behaviors on plasma aldosterone in humans

Thosar, S. S., Rueda, J., Berman, A. M., Lasarev, M. R., Herzig, M. X., Clemons, N. A., Roberts, S. A., Bowles, N. P., Emens, J., Ellison, D. & Shea, S., Feb 1 2019, In : American journal of physiology. Regulatory, integrative and comparative physiology. 316, 2, p. R157-R164

Research output: Contribution to journalArticle

Aldosterone
Sleep
Wakefulness
Healthy Volunteers
Exercise

Serum Bicarbonate as a Surrogate for pH in Hemodialysis: A Pilot Study

Woodell, T. B., Rifkin, D. E., Ellison, D. H., Negoianu, D. & Weiss, J. W., Jan 1 2019, (Accepted/In press) In : Kidney Medicine.

Research output: Contribution to journalArticle

Open Access
Bicarbonates
Renal Dialysis
Serum
Acids
Chronic Kidney Failure

WNK4 limits distal calcium losses following acute furosemide treatment

Ferdaus, M. Z., Gratreak, B. D. K., Miller, L., Si, J., McCormick, J. J., Yang, C-L., Ellison, D. & Terker, A. S., Sep 1 2019, In : Physiological reports. 7, 17, p. e14195

Research output: Contribution to journalArticle

Open Access
Furosemide
Calcium
Nephrons
Extremities
Diet
2018
1 Citation (Scopus)

C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity

Murillo-de-Ozores, A. R., Rodríguez-Gama, A., Bazúa-Valenti, S., Leyva-Ríos, K., Vázquez, N., Pacheco-Álvarez, D., De La Rosa-Velázquez, I. A., Wengi, A., Stone, K. L., Zhang, J., Loffing, J., Lifton, R. P., Yang, C-L., Ellison, D., Gamba, G. & Castañeda-Bueno, M., Jan 1 2018, In : Journal of Biological Chemistry. 293, 31, p. 12209-12221 13 p.

Research output: Contribution to journalArticle

Protein Phosphatase 1
Phosphotransferases
Kidney
Binding Sites
Member 3 Solute Carrier Family 12
2 Citations (Scopus)

Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension

Cornelius, R. J., Zhang, C., Erspamer, K. J., Agbor, L. N., Sigmund, C. D., Singer, J. D., Yang, C-L. & Ellison, D., Oct 1 2018, In : American journal of physiology. Renal physiology. 315, 4, p. F1006-F1018

Research output: Contribution to journalArticle

Cullin Proteins
Ligases
Ubiquitin
Hypertension
Mutation
4 Citations (Scopus)

Endothelial transcriptomics reveals activation of fibrosis-related pathways in hypertension

Nelson, J. W., Ferdaus, M. Z., McCormick, J. J., Minnier, J., Kaul, S., Ellison, D. & Barnes, A., Feb 1 2018, In : Physiological Genomics. 50, 2, p. 104-116 13 p.

Research output: Contribution to journalArticle

Fibrosis
Hypertension
Endothelial Cells
Blood Pressure
RNA Sequence Analysis
5 Citations (Scopus)

Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC

Argaiz, E. R., Chavez-Canales, M., Ostrosky-Frid, M., Rodríguez-Gama, A., Vázquez, N., Gonzalez-Rodriguez, X., Garcia-Valdes, J., Hadchouel, J., Ellison, D. & Gamba, G., Sep 6 2018, In : American Journal of Physiology - Renal Physiology. 315, 3, p. F734-F745

Research output: Contribution to journalArticle

Member 3 Solute Carrier Family 12
Lysine
Protein Isoforms
Kidney
Phosphotransferases
6 Citations (Scopus)

Optical Clearing in the Kidney Reveals Potassium-Mediated Tubule Remodeling

Saritas, T., Puelles, V. G., Su, X. T., McCormick, J. J., Welling, P. A. & Ellison, D., Dec 4 2018, In : Cell Reports. 25, 10, p. 2668-2675.e3

Research output: Contribution to journalArticle

Potassium
Nephrons
Kidney
Nutrition
Microscopy
20 Citations (Scopus)

Potassium intake modulates the thiazide-sensitive sodium-chloride cotransporter (NCC) activity via the Kir4.1 potassium channel

Wang, M. X., Cuevas, C. A., Su, X. T., Wu, P., Gao, Z. X., Lin, D. H., McCormick, J. J., Yang, C-L., Wang, W. H. & Ellison, D., Jan 1 2018, (Accepted/In press) In : Kidney International.

Research output: Contribution to journalArticle

Member 3 Solute Carrier Family 12
Potassium Channels
Potassium
Dietary Potassium
Knockout Mice
2 Citations (Scopus)

Renal COP9 signalosome deficiency alters CUL3-KLHL3-WNK signaling pathway

Cornelius, R. J., Si, J., Cuevas, C. A., Nelson, J. W., Gratreak, B. D. K., Pardi, R., Yang, C-L. & Ellison, D., Nov 1 2018, In : Journal of the American Society of Nephrology. 29, 11, p. 2627-2640 14 p.

Research output: Contribution to journalArticle

Cullin Proteins
Member 3 Solute Carrier Family 12
Kidney
Phenotype
Phosphotransferases

Role of WNK4 and kidney-specific WNK1 in mediating the effect of high dietary K+ intake on ROMK channel in the distal convoluted tubule

Wu, P., Gao, Z. X., Su, X. T., Ellison, D., Hadchouel, J., Teulon, J. & Wang, W. H., Aug 1 2018, In : American Journal of Physiology - Renal Physiology. 315, 2, p. F223-F230

Research output: Contribution to journalArticle

Lysine
Phosphotransferases
Kidney
Collecting Kidney Tubules
Kidney Tubules
4 Citations (Scopus)

The Calcium-Sensing Receptor Increases Activity of the Renal NCC through the WNK4-SPAK Pathway

Bazúa-Valenti, S., Rojas-Vega, L., Castañeda-Bueno, M., Barrera-Chimal, J., Bautista, R., Cervantes-Pérez, L. G., Vázquez, N., Plata, C., Murillo-de-Ozores, A. R., González-Mariscal, L., Ellison, D., Riccardi, D., Bobadilla, N. A. & Gamba, G., Jul 1 2018, In : Journal of the American Society of Nephrology. 29, 7, p. 1838-1848 11 p.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Kidney
N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine
Hypercalciuria
HEK293 Cells
4 Citations (Scopus)

With no lysine kinase 4 modulates sodium potassium 2 chloride cotransporter activity in vivo

Terker, A. S., Castañeda-Bueno, M., Ferdaus, M. Z., Cornelius, R. J., Erspamer, K. J., Su, X. T., Miller, L. N., McCormick, J. J., Wang, W. H., Gamba, G., Yang, C-L. & Ellison, D., Oct 1 2018, In : American Journal of Physiology - Renal Physiology. 315, 4, p. F781-F790

Research output: Contribution to journalArticle

Sodium-Potassium-Chloride Symporters
Lysine
Phosphotransferases
Member 1 Solute Carrier Family 12
Knockout Mice
2017
13 Citations (Scopus)

Calcineurin inhibitor cyclosporine A activates renal NA-K-CL cotransporters via local and systemic mechanisms

Blankenstein, K. I., Borschewski, A., Labes, R., Paliege, A., Boldt, C., McCormick, J. J., Ellison, D., Bader, M., Bachmann, S. & Mutig, K., Mar 1 2017, In : American Journal of Physiology - Renal Physiology. 312, 3, p. F489-F501

Research output: Contribution to journalArticle

Member 3 Solute Carrier Family 12
Arginine Vasopressin
Cyclosporine
Kidney
Calcineurin
16 Citations (Scopus)

Compensatory distal reabsorption drives diuretic resistance in human heart failure

Rao, V. S., Planavsky, N., Hanberg, J. S., Ahmad, T., Brisco-Bacik, M. A., Wilson, F. P., Jacoby, D., Chen, M., Tang, W. H. W., Cherney, D. Z. I., Ellison, D. & Testani, J. M., Nov 1 2017, In : Journal of the American Society of Nephrology. 28, 11, p. 3414-3424 11 p.

Research output: Contribution to journalArticle

Diuretics
Heart Failure
Sodium Potassium Chloride Symporter Inhibitors
Sodium
Lithium
48 Citations (Scopus)

Gitelman syndrome: consensus and guidance from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Blanchard, A., Bockenhauer, D., Bolignano, D., Calò, L. A., Cosyns, E., Devuyst, O., Ellison, D., Karet Frankl, F. E., Knoers, N. V. A. M., Konrad, M., Lin, S. H. & Vargas-Poussou, R., Jan 1 2017, In : Kidney International. 91, 1, p. 24-33 10 p.

Research output: Contribution to journalArticle

Gitelman Syndrome
Kidney Diseases
Member 3 Solute Carrier Family 12
Salts
Alkalosis
34 Citations (Scopus)

Potassium sensing by renal distal tubules requires Kir4.1

Cuevas, C. A., Su, X. T., Wang, M. X., Terker, A. S., Lin, D. H., McCormick, J. J., Yang, C-L., Ellison, D. & Wang, W. H., Jun 1 2017, In : Journal of the American Society of Nephrology. 28, 6, p. 1814-1825 12 p.

Research output: Contribution to journalArticle

Distal Kidney Tubule
Potassium
Thiazides
Membranes
Hypokalemia
25 Citations (Scopus)

Renal tubular resistance is the primary driver for loop diuretic resistance in acute heart failure

ter Maaten, J. M., Rao, V. S., Hanberg, J. S., Perry Wilson, F., Bellumkonda, L., Assefa, M., Sam Broughton, J., D'Ambrosi, J., Wilson Tang, W. H., Damman, K., Voors, A. A., Ellison, D. & Testani, J. M., 2017, (Accepted/In press) In : European Journal of Heart Failure.

Research output: Contribution to journalArticle

Sodium Potassium Chloride Symporter Inhibitors
Diuretics
Heart Failure
Bumetanide
Kidney
2016

Anaesthesia recommendations for patients suffering from Liddle's syndrome

McCaul, C., Caulfield, K., Sinha, R. & Ellison, D., Sep 1 2016, In : Anasthesiologie und Intensivmedizin. 57, 9, p. S500-S505

Research output: Contribution to journalArticle

Liddle Syndrome
Anesthesia
Hypertension
Epithelial Sodium Channel Blockers
Triamterene
14 Citations (Scopus)

Calcineurin and Sorting-Related Receptor with A-Type Repeats Interact to Regulate the Renal Na+-K+-2Cl- Cotransporter

Borschewski, A., Himmerkus, N., Boldt, C., Blankenstein, K. I., McCormick, J. J., Lazelle, R., Willnow, T. E., Jankowski, V., Plain, A., Bleich, M., Ellison, D., Bachmann, S. & Mutig, K., Jan 1 2016, In : Journal of the American Society of Nephrology. 27, 1, p. 107-119 13 p.

Research output: Contribution to journalArticle

Calcineurin
Kidney
Extremities
Cyclosporine
Member 1 Solute Carrier Family 12
7 Citations (Scopus)

Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension

Zhang, C., Meermeier, N. P., Terker, A. S., Blankenstein, K. I., Singer, J. D., Hadchouel, J., Ellison, D. & Yang, C-L., Jan 1 2016, In : Biochemical and Biophysical Research Communications. 469, 1, p. 44-48 5 p.

Research output: Contribution to journalArticle

Cullin Proteins
Phosphotransferases
Hypertension
Degradation
Mutation
39 Citations (Scopus)

Direct and indirect mineralocorticoid effects determine distal salt transport

Terker, A. S., Yarbrough, B., Ferdaus, M. Z., Lazelle, R. A., Erspamer, K. J., Meermeier, N. P., Park, H. J., McCormick, J. J., Yang, C-L. & Ellison, D., 2016, In : Journal of the American Society of Nephrology. 27, 8, p. 2436-2445 10 p.

Research output: Contribution to journalArticle

Mineralocorticoids
Aldosterone
Salts
Nephrons
Dietary Potassium
21 Citations (Scopus)

Diuretic Resistance

Hoorn, E. J. & Ellison, D., Feb 23 2016, (Accepted/In press) In : American Journal of Kidney Diseases.

Research output: Contribution to journalArticle

Diuretics
Sodium Potassium Chloride Symporter Inhibitors
Edema
Nephrotic Syndrome
Epithelial Sodium Channel Blockers
72 Citations (Scopus)

Regulation of Renal Electrolyte Transport by WNK and SPAK-OSR1 Kinases

Hadchouel, J., Ellison, D. & Gamba, G., Feb 10 2016, In : Annual Review of Physiology. 78, p. 367-389 23 p.

Research output: Contribution to journalArticle

Member 3 Solute Carrier Family 12
Protein-Serine-Threonine Kinases
Electrolytes
Phosphotransferases
Pseudohypoaldosteronism
22 Citations (Scopus)

Renal deletion of 12 kDa FK506-binding protein attenuates tacrolimus-induced hypertension

Lazelle, R. A., McCully, B., Terker, A. S., Himmerkus, N., Blankenstein, K. I., Mutig, K., Bleich, M., Bachmann, S., Yang, C-L. & Ellison, D., May 1 2016, In : Journal of the American Society of Nephrology. 27, 5, p. 1456-1464 9 p.

Research output: Contribution to journalArticle

Tacrolimus Binding Proteins
Tacrolimus
Tacrolimus Binding Protein 1A
Hypertension
Kidney
2015
3 Citations (Scopus)

An integrated view of potassium homeostasis

Hoorn, E. J., Loffing, J. & Ellison, D., Oct 29 2015, In : New England Journal of Medicine. 373, 18, p. 1786 1 p.

Research output: Contribution to journalArticle

Potassium
Homeostasis

An Integrated View of Potassium Homeostasis

Hoorn, E. J., Loffing, J. & Ellison, D. H., Oct 29 2015, In : The New England journal of medicine. 373, 18, p. 1786 1 p.

Research output: Contribution to journalArticle

Circadian Clocks
Potassium
Homeostasis
37 Citations (Scopus)

Distal convoluted tubule

McCormick, J. J. & Ellison, D., Jan 1 2015, In : Comprehensive Physiology. 5, 1, p. 45-98 54 p.

Research output: Contribution to journalArticle

Nephrons
Member 3 Solute Carrier Family 12
Gitelman Syndrome
Wasting Syndrome
Transient Receptor Potential Channels
4 Citations (Scopus)

Evaluating hyponatremia

Cohen, D. & Ellison, D., Mar 24 2015, In : JAMA - Journal of the American Medical Association. 313, 12, p. 1260-1261 2 p.

Research output: Contribution to journalArticle

Inappropriate ADH Syndrome
Hyponatremia
Haloperidol
Sodium Chloride
Abdominal Pain
28 Citations (Scopus)

Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter

Wang, J., Sun, C., Gerdes, N., Liu, C., Liao, M., Liu, J., Shi, M. A., He, A., Zhou, Y., Sukhova, G. K., Chen, H., Cheng, X. W., Kuzuya, M., Murohara, T., Zhang, J., Cheng, X., Jiang, M., Shull, G. E., Rogers, S., Yang, C-L. & 7 others, Ke, Q., Jelen, S., Bindels, R., Ellison, D., Jarolim, P., Libby, P. & Shi, G. P., Jun 22 2015, In : Nature Medicine. 21, 7, p. 820-826 7 p.

Research output: Contribution to journalArticle

Interleukin-18 Receptors
Symporters
Interleukin-18
Atherosclerosis
Apolipoproteins E

Outstanding translational science at American Society of Hypertension 2015

Ellison, D., Nov 1 2015, In : Journal of the American Society of Hypertension. 9, 11, p. 828-830 3 p.

Research output: Contribution to journalArticle

Translational Medical Research
Medical Societies
Program Evaluation
Quality Improvement
Antihypertensive Agents
157 Citations (Scopus)

Potassium modulates electrolyte balance and blood pressure through effects on distal cell voltage and chloride

Terker, A. S., Zhang, C., McCormick, J. J., Lazelle, R. A., Zhang, C., Meermeier, N. P., Siler, D. A., Park, H. J., Fu, Y., Cohen, D., Weinstein, A. M., Wang, W. H., Yang, C-L. & Ellison, D., Jan 6 2015, In : Cell Metabolism. 21, 1, p. 39-50 12 p.

Research output: Contribution to journalArticle

Water-Electrolyte Balance
Chlorides
Potassium
Blood Pressure
Dietary Potassium
6 Citations (Scopus)

Renal mineralocorticoid receptor and electrolyte homeostasis

Terker, A. S. & Ellison, D., 2015, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 309, 9, p. R1068-R1070

Research output: Contribution to journalArticle

Mineralocorticoid Receptors
Electrolytes
Homeostasis
Kidney
Steroid Receptors
64 Citations (Scopus)

The effect of WNK4 on the Na+-Cl- cotransporter is modulated by intracellular chloride

Bazúa-Valenti, S., Chávez-Canales, M., Rojas-Vega, L., González-Rodríguez, X., Vázquez, N., Rodríguez-Gama, A., Argaiz, E. R., Melo, Z., Plata, C., Ellison, D., García-Valdés, J., Hadchouel, J. & Gamba, G., Aug 1 2015, In : Journal of the American Society of Nephrology. 26, 8, p. 1781-1786 6 p.

Research output: Contribution to journalArticle

Member 3 Solute Carrier Family 12
Chlorides
Complementary RNA
Oocytes
Protein Isoforms
88 Citations (Scopus)

Unique chloride-sensing properties of WNK4 permit the distal nephron to modulate potassium homeostasis

Terker, A. S., Zhang, C., Erspamer, K. J., Gamba, G., Yang, C-L. & Ellison, D., Sep 30 2015, (Accepted/In press) In : Kidney International.

Research output: Contribution to journalArticle

Nephrons
Chlorides
Potassium
Homeostasis
Phosphotransferases
13 Citations (Scopus)

Why Your Mother Was Right: How Potassium Intake Reduces Blood Pressure

Ellison, D. & Terker, A. S., 2015, In : Transactions of the American Clinical and Climatological Association. 126, p. 46-55 10 p.

Research output: Contribution to journalArticle

Potassium
Salts
Blood Pressure
Dietary Potassium
Potassium Deficiency
2014
10 Citations (Scopus)

A quest - Halting the progression of autosomal dominant polycystic kidney disease

Ellison, D. & Ingelfinger, J. R., Dec 11 2014, In : New England Journal of Medicine. 371, 24, p. 2329-2331 3 p.

Research output: Contribution to journalArticle

Benzimidazoles
Lisinopril
Angiotensin II Type 1 Receptor Blockers
Autosomal Dominant Polycystic Kidney
Benzoates
9 Citations (Scopus)

Bardoxolone methyl in type 2 diabetes and advanced chronic kidney disease

Ellison, D., 2014, In : New England Journal of Medicine. 370, 18, p. 1768 1 p.

Research output: Contribution to journalArticle

Oleanolic Acid
Diabetic Nephropathies
Chronic Renal Insufficiency
Type 2 Diabetes Mellitus
Chronic Kidney Failure
77 Citations (Scopus)

Distal convoluted tubule

Subramanya, A. R. & Ellison, D., 2014, In : Clinical Journal of the American Society of Nephrology. 9, 12, p. 2147-2163 17 p.

Research output: Contribution to journalArticle

Nephrons
Divalent Cations
Potassium
Homeostasis
Sodium
57 Citations (Scopus)

Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3

McCormick, J. J., Yang, C-L., Zhang, C., Davidge, B., Blankenstein, K. I., Terker, A. S., Yarbrough, B., Meermeier, N. P., Park, H. J., McCully, B., West, M., Borschewski, A., Himmerkus, N., Bleich, M., Bachmann, S., Mutig, K., Argaiz, E. R., Gamba, G., Singer, J. D. & Ellison, D., Nov 3 2014, In : Journal of Clinical Investigation. 124, 11, p. 4723-4736 14 p.

Research output: Contribution to journalArticle

Cullin Proteins
Hypertension
Phosphotransferases
Kidney
Member 3 Solute Carrier Family 12
36 Citations (Scopus)

Protein phosphatase 1 inhibitor-1 deficiency reduces phosphorylation of renal NaCl cotransporter and causes arterial hypotension

Picard, N., Trompf, K., Yang, C-L., Miller, R. L., Carrel, M., Loffing-Cueni, D., Fenton, R. A., Ellison, D. & Loffing, J., Mar 2014, In : Journal of the American Society of Nephrology. 25, 3, p. 511-522 12 p.

Research output: Contribution to journalArticle

Hypotension
Phosphorylation
Kidney
Gitelman Syndrome
Distal Kidney Tubule
32 Citations (Scopus)

Sympathetic stimulation of thiazide-sensitive sodium chloride cotransport in the generation of salt-sensitive hypertension

Terker, A. S., Yang, C-L., McCormick, J. J., Meermeier, N. P., Rogers, S. L., Grossmann, S., Trompf, K., Delpire, E., Loffing, J. & Ellison, D., 2014, In : Hypertension. 64, 1, p. 178-184 7 p.

Research output: Contribution to journalArticle

Thiazides
Sodium Chloride
Phosphotransferases
Salts
Hypertension