David Ellison

Professor

  • 8917 Citations
  • 52 h-Index
1982 …2020

Research output per year

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Research Output

2020

Diuretic Therapy for Patients With Heart Failure: JACC State-of-the-Art Review

Felker, G. M., Ellison, D. H., Mullens, W., Cox, Z. L. & Testani, J. M., Mar 17 2020, In : Journal of the American College of Cardiology. 75, 10, p. 1178-1195 18 p.

Research output: Contribution to journalReview article

4 Scopus citations

Effect of Angiotensin II on ENaC in the Distal Convoluted Tubule and in the Cortical Collecting Duct of Mineralocorticoid Receptor Deficient Mice

Wu, P., Gao, Z. X., Zhang, D. D., Duan, X. P., Terker, A. S., Lin, D. H., Ellison, D. H. & Wang, W. H., Apr 7 2020, In : Journal of the American Heart Association. 9, 7, p. e014996

Research output: Contribution to journalArticle

Open Access

Hypertension-causing cullin 3 mutations disrupt COP9 signalosome binding

Cornelius, R. J., Yang, C. L. & Ellison, D. H., Jan 1 2020, In : American Journal of Physiology - Renal Physiology. 318, 1, p. F204-F208

Research output: Contribution to journalReview article

1 Scopus citations

Kidney Is Essential for Blood Pressure Modulation by Dietary Potassium

Su, X. T., Yang, C. L. & Ellison, D. H., Oct 1 2020, In : Current cardiology reports. 22, 10, 124.

Research output: Contribution to journalReview article

Open Access

Potassium homeostasis and management of dyskalemia in kidney diseases: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Clase, C. M., Carrero, J. J., Ellison, D. H., Grams, M. E., Hemmelgarn, B. R., Jardine, M. J., Kovesdy, C. P., Kline, G. A., Lindner, G., Obrador, G. T., Palmer, B. F., Cheung, M., Wheeler, D. C., Winkelmayer, W. C., Pecoits-Filho, R., Ashuntantang, G. E., Bakker, S. J. L., Bakris, G. L., Bhandari, S., Burdmann, E. A. & 33 others, Campbell, K. L., Charytan, D. M., Clegg, D. J., Cuppari, L., Goldsmith, D., Hallan, S. I., He, J., Herzog, C. A., Hoenig, M. P., Hoorn, E. J., Leipziger, J. G., Leonberg-Yoo, A. K., Lerma, E. V., Lopez-Almaraz, J. E., Małyszko, J., Mann, J. F. E., Marklund, M., McDonough, A. A., Nagahama, M., Navaneethan, S. D., Pitt, B., Pochynyuk, O. M., Proença de Moraes, T., Rafique, Z., Robinson, B. M., Roger, S. D., Rossignol, P., Singer, A. J., Smyth, A., Sood, M. M., Walsh, M., Weir, M. R. & Wingo, C. S., Jan 2020, In : Kidney International. 97, 1, p. 42-61 20 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Tacrolimus-induced hypomagnesemia and hypercalciuria requires FKBP12 suggesting a role for calcineurin

Gratreak, B. D. K., Swanson, E. A., Lazelle, R. A., Jelen, S. K., Hoenderop, J., Bindels, R. J., Yang, C. L. & Ellison, D. H., Jan 1 2020, In : Physiological reports. 8, 1, e14316.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

The authors reply

Ellison, D. H. & Palmer, B. F., Sep 2020, In : Kidney International. 98, 3, p. 785 1 p.

Research output: Contribution to journalLetter

WNK bodies cluster WNK4 and SPAK/OSR1 to promote NCC activation in hypokalemia

Thomson, M. N., Cuevas, C. A., Bewarder, T. M., Dittmayer, C., Miller, L. N., Si, J., Cornelius, R. J., Su, X. T., Yang, C. L., McCormick, J. A., Hadchouel, J., Ellison, D. H., Bachmann, S. & Mutig, K., Jan 1 2020, In : American Journal of Physiology - Renal Physiology. 318, 1, p. F216-F228

Research output: Contribution to journalArticle

1 Scopus citations
2019

Animal Models of Hypertension: A Scientific Statement From the American Heart Association

Lerman, L. O., Kurtz, T. W., Touyz, R. M., Ellison, D. H., Chade, A. R., Crowley, S. D., Mattson, D. L., Mullins, J. J., Osborn, J., Eirin, A., Reckelhoff, J. F., Iadecola, C. & Coffman, T. M., Jun 1 2019, In : Hypertension (Dallas, Tex. : 1979). 73, 6, p. e87-e120

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

Clinical pharmacology in diuretic use

Ellison, D. H., Aug 7 2019, In : Clinical Journal of the American Society of Nephrology. 14, 8, p. 1248-1257 10 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Enemy action in the distal convoluted tubule

Ellison, D. H. & Lin, S. H., Aug 2019, In : Journal of the American Society of Nephrology. 30, 8, p. 1345-1348 4 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Kir4.1/kir5.1 in the DCT plays a role in the regulation of renal K+ excretion

Su, X. T., Ellison, D. H. & Wang, W. H., Mar 2019, In : American Journal of Physiology - Renal Physiology. 316, 3, p. F582-F586

Research output: Contribution to journalReview article

9 Scopus citations

Mechanistic insights into loop diuretic responsiveness in heart failure

Ellison, D. H., May 7 2019, In : Clinical Journal of the American Society of Nephrology. 14, 5, p. 650-652 3 p.

Research output: Contribution to journalEditorial

Optical clearing and imaging of immunolabeled kidney tissue

Saritas, T., Puelles, V. G., Su, X. T., Ellison, D. H. & Kramann, R., Jul 2019, In : Journal of Visualized Experiments. 2019, 149, e60002.

Research output: Contribution to journalArticle

Optical tissue clearing and immunolabeling in kidney research

Su, X. T., Saritas, T. & Ellison, D. H., 2019, Methods in Cell Biology. Weimbs, T. (ed.). Academic Press Inc., p. 31-41 11 p. (Methods in Cell Biology; vol. 154).

Research output: Chapter in Book/Report/Conference proceedingChapter

Patients with hypokalemia develop WNK bodies in the distal convoluted tubule of the kidney

Thomson, M. N., Schneider, W., Mutig, K., Ellison, D., Kettritz, R. & Bachmann, S., Feb 1 2019, In : American journal of physiology. Renal physiology. 316, 2, p. F292-F300

Research output: Contribution to journalArticle

3 Scopus citations

Renal-tubule epithelial cell nomenclature for single-cell rna-sequencing studies

Chen, L., Clark, J. Z., Nelson, J. W., Kaissling, B., Ellison, D. H. & Knepper, M. A., Aug 2019, In : Journal of the American Society of Nephrology. 30, 8, p. 1358-1364 7 p.

Research output: Contribution to journalReview article

4 Scopus citations

Salt-sensitive transcriptome of isolated kidney distal tubule cells

Swanson, E. A., Nelson, J. W., Jeng, S., Erspamer, K. J., Yang, C. L., McWeeney, S. & Ellison, D. H., Apr 2019, In : Physiological genomics. 51, 4, p. 125-135 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Separate and interacting effects of the endogenous circadian system and behaviors on plasma aldosterone in humans

Thosar, S. S., Rueda, J. F., Berman, A. M., Lasarev, M. R., Herzig, M. X., Clemons, N. A., Roberts, S. A., Bowles, N. P., Emens, J. S., Ellison, D. H. & Shea, S. A., Feb 2019, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 316, 2, p. R157-R164

Research output: Contribution to journalArticle

3 Scopus citations

Serum Bicarbonate as a Surrogate for pH in Hemodialysis: A Pilot Study

Woodell, T. B., Rifkin, D. E., Ellison, D. H., Negoianu, D. & Weiss, J. W., Jan 1 2019, (Accepted/In press) In : Kidney Medicine.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Why are physicians so confused about acute heart failure?

Ellison, D. H., Dec 12 2019, In : New England Journal of Medicine. 381, 24, p. 2374-2375 2 p.

Research output: Contribution to journalLetter

WNK4 limits distal calcium losses following acute furosemide treatment

Ferdaus, M. Z., Gratreak, B. D. K., Miller, L., Si, J., McCormick, J. A., Yang, C. L., Ellison, D. H. & Terker, A. S., Sep 1 2019, In : Physiological reports. 7, 17, e14195.

Research output: Contribution to journalArticle

Open Access
2018

C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity

Murillo-de-Ozores, A. R., Rodríguez-Gama, A., Bazúa-Valenti, S., Leyva-Ríos, K., Vázquez, N., Pacheco-Álvarez, D., De La Rosa-Velázquez, I. A., Wengi, A., Stone, K. L., Zhang, J., Loffing, J., Lifton, R. P., Yang, C. L., Ellison, D. H., Gamba, G. & Castañeda-Bueno, M., Aug 3 2018, In : Journal of Biological Chemistry. 293, 31, p. 12209-12221 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension

Cornelius, R. J., Zhang, C., Erspamer, K. J., Agbor, L. N., Sigmund, C. D., Singer, J. D., Yang, C. L. & Ellison, D. H., Oct 2018, In : American Journal of Physiology - Renal Physiology. 315, 4, p. F1006-F1018

Research output: Contribution to journalArticle

6 Scopus citations

Endothelial transcriptomics reveals activation of fibrosis-related pathways in hypertension

Nelson, J. W., Ferdaus, M. Z., McCormick, J. A., Minnier, J., Kaul, S., Ellison, D. H. & Barnes, A. P., Feb 2018, In : Physiological genomics. 50, 2, p. 104-116 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC

Argaiz, E. R., Chavez-Canales, M., Ostrosky-Frid, M., Rodríguez-Gama, A., Vázquez, N., Gonzalez-Rodriguez, X., Garcia-Valdes, J., Hadchouel, J., Ellison, D. & Gamba, G., Sep 6 2018, In : American Journal of Physiology - Renal Physiology. 315, 3, p. F734-F745

Research output: Contribution to journalArticle

12 Scopus citations

Optical Clearing in the Kidney Reveals Potassium-Mediated Tubule Remodeling

Saritas, T., Puelles, V. G., Su, X. T., McCormick, J. A., Welling, P. A. & Ellison, D. H., Dec 4 2018, In : Cell Reports. 25, 10, p. 2668-2675.e3

Research output: Contribution to journalArticle

13 Scopus citations

Potassium intake modulates the thiazide-sensitive sodium-chloride cotransporter (NCC) activity via the Kir4.1 potassium channel

Wang, M. X., Cuevas, C. A., Su, X. T., Wu, P., Gao, Z. X., Lin, D. H., McCormick, J. A., Yang, C. L., Wang, W. H. & Ellison, D. H., Apr 2018, In : Kidney International. 93, 4, p. 893-902 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

Renal COP9 signalosome deficiency alters CUL3-KLHL3-WNK signaling pathway

Cornelius, R. J., Si, J., Cuevas, C. A., Nelson, J. W., Gratreak, B. D. K., Pardi, R., Yang, C. L. & Ellison, D. H., Nov 2018, In : Journal of the American Society of Nephrology. 29, 11, p. 2627-2640 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

Role of WNK4 and kidney-specific WNK1 in mediating the effect of high dietary K+ intake on ROMK channel in the distal convoluted tubule

Wu, P., Gao, Z. X., Su, X. T., Ellison, D. H., Hadchouel, J., Teulon, J. & Wang, W. H., Aug 2018, In : American Journal of Physiology - Renal Physiology. 315, 2, p. F223-F230

Research output: Contribution to journalArticle

4 Scopus citations

The Calcium-Sensing Receptor Increases Activity of the Renal NCC through the WNK4-SPAK Pathway

Bazúa-Valenti, S., Rojas-Vega, L., Castañeda-Bueno, M., Barrera-Chimal, J., Bautista, R., Cervantes-Pérez, L. G., Vázquez, N., Plata, C., Murillo-de-Ozores, A. R., González-Mariscal, L., Ellison, D. H., Riccardi, D., Bobadilla, N. A. & Gamba, G., Jul 2018, In : Journal of the American Society of Nephrology. 29, 7, p. 1838-1848 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

With no lysine kinase 4 modulates sodium potassium 2 chloride cotransporter activity in vivo

Terker, A. S., Castañeda-Bueno, M., Ferdaus, M. Z., Cornelius, R. J., Erspamer, K. J., Su, X. T., Miller, L. N., McCormick, J. A., Wang, W. H., Gamba, G., Yang, C. L. & Ellison, D. H., Oct 2018, In : American Journal of Physiology - Renal Physiology. 315, 4, p. F781-F790

Research output: Contribution to journalArticle

10 Scopus citations
2017

Calcineurin inhibitor cyclosporine A activates renal NA-K-CL cotransporters via local and systemic mechanisms

Blankenstein, K. I., Borschewski, A., Labes, R., Paliege, A., Boldt, C., McCormick, J. A., Ellison, D. H., Bader, M., Bachmann, S. & Mutig, K., Mar 2017, In : American Journal of Physiology - Renal Physiology. 312, 3, p. F489-F501

Research output: Contribution to journalArticle

17 Scopus citations

Compensatory distal reabsorption drives diuretic resistance in human heart failure

Rao, V. S., Planavsky, N., Hanberg, J. S., Ahmad, T., Brisco-Bacik, M. A., Wilson, F. P., Jacoby, D., Chen, M., Tang, W. H. W., Cherney, D. Z. I., Ellison, D. H. & Testani, J. M., Nov 2017, In : Journal of the American Society of Nephrology. 28, 11, p. 3414-3424 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Diuretic Resistance

Hoorn, E. J. & Ellison, D. H., Jan 1 2017, In : American Journal of Kidney Diseases. 69, 1, p. 136-142 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Diuretic treatment in heart failure

Ellison, D. H. & Felker, G. M., Nov 16 2017, In : New England Journal of Medicine. 377, 20, p. 1964-1975 12 p.

Research output: Contribution to journalReview article

74 Scopus citations

Genetic Risk, Lifestyle, and Coronary Artery Disease

Ellison, D., Mar 23 2017, In : The New England journal of medicine. 376, 12, 1 p.

Research output: Contribution to journalLetter

Gitelman syndrome: consensus and guidance from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Blanchard, A., Bockenhauer, D., Bolignano, D., Calò, L. A., Cosyns, E., Devuyst, O., Ellison, D. H., Karet Frankl, F. E., Knoers, N. V. A. M., Konrad, M., Lin, S. H. & Vargas-Poussou, R., Jan 1 2017, In : Kidney International. 91, 1, p. 24-33 10 p.

Research output: Contribution to journalArticle

72 Scopus citations
2 Scopus citations

Potassium sensing by renal distal tubules requires Kir4.1

Cuevas, C. A., Su, X. T., Wang, M. X., Terker, A. S., Lin, D. H., Mccormick, J. A., Yang, C. L., Ellison, D. H. & Wang, W. H., Jun 2017, In : Journal of the American Society of Nephrology. 28, 6, p. 1814-1825 12 p.

Research output: Contribution to journalArticle

52 Scopus citations

Renal tubular resistance is the primary driver for loop diuretic resistance in acute heart failure

ter Maaten, J. M., Rao, V. S., Hanberg, J. S., Perry Wilson, F., Bellumkonda, L., Assefa, M., Sam Broughton, J., D'Ambrosi, J., Wilson Tang, W. H., Damman, K., Voors, A. A., Ellison, D. H. & Testani, J. M., Aug 2017, In : European Journal of Heart Failure. 19, 8, p. 1014-1022 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Treatment of Disorders of Sodium Balance in Chronic Kidney Disease

Ellison, D. H., Sep 1 2017, In : Advances in Chronic Kidney Disease. 24, 5, p. 332-341 10 p.

Research output: Contribution to journalReview article

9 Scopus citations

WNK Kinase Signaling in Ion Homeostasis and Human Disease

Shekarabi, M., Zhang, J., Khanna, A. R., Ellison, D. H., Delpire, E. & Kahle, K. T., Feb 7 2017, In : Cell Metabolism. 25, 2, p. 285-299 15 p.

Research output: Contribution to journalReview article

62 Scopus citations
2016

Anaesthesia recommendations for patients suffering from Liddle's syndrome

McCaul, C., Caulfield, K., Sinha, R. & Ellison, D., Sep 1 2016, In : Anasthesiologie und Intensivmedizin. 57, 9, p. S500-S505

Research output: Contribution to journalArticle

Calcineurin and Sorting-Related Receptor with A-Type Repeats Interact to Regulate the Renal Na+-K+-2Cl- Cotransporter

Borschewski, A., Himmerkus, N., Boldt, C., Blankenstein, K. I., McCormick, J. A., Lazelle, R., Willnow, T. E., Jankowski, V., Plain, A., Bleich, M., Ellison, D. H., Bachmann, S. & Mutig, K., Jan 2016, In : Journal of the American Society of Nephrology. 27, 1, p. 107-119 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension

Zhang, C., Meermeier, N. P., Terker, A. S., Blankenstein, K. I., Singer, J. D., Hadchouel, J., Ellison, D. H. & Yang, C. L., Jan 1 2016, In : Biochemical and Biophysical Research Communications. 469, 1, p. 44-48 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Direct and indirect mineralocorticoid effects determine distal salt transport

Terker, A. S., Yarbrough, B., Ferdaus, M. Z., Lazelle, R. A., Erspamer, K. J., Meermeier, N. P., Park, H. J., McCormick, J. A., Yang, C. L. & Ellison, D. H., 2016, In : Journal of the American Society of Nephrology. 27, 8, p. 2436-2445 10 p.

Research output: Contribution to journalArticle

50 Scopus citations

Potassium and its discontents: New insight, new treatments

Ellison, D. H., Terker, A. S. & Gamba, G., Apr 2016, In : Journal of the American Society of Nephrology. 27, 4

Research output: Contribution to journalReview article

39 Scopus citations

Regulation of Renal Electrolyte Transport by WNK and SPAK-OSR1 Kinases

Hadchouel, J., Ellison, D. & Gamba, G., Feb 10 2016, In : Annual Review of Physiology. 78, p. 367-389 23 p.

Research output: Contribution to journalArticle

89 Scopus citations