David Cohen

Professor

  • 3850 Citations
  • 35 h-Index
1990 …2019

Research output per year

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Research Output

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Article
2019

Heritability and individuality of the plasma sodium concentration: a twin study in the United States veteran population

Timmons, A. K., Korpak, A. M., Tan, J., Moore, K. P., Liu, C. H., Forsberg, C. W., Goldberg, J., Smith, N. L. & Cohen, D., Jun 1 2019, In : American journal of physiology. Renal physiology. 316, 6, p. F1114-F1123

Research output: Contribution to journalArticle

2 Scopus citations
2018

Elephant in the room

Hartung, D. M., Johnston, K., Cohen, D., Nguyen, T., Deodhar, A. A. & Bourdette, D., Jan 23 2018, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

1 Scopus citations
2017

NFAT5 and SLC4A10 loci associate with plasma osmolality

Böger, C. A., Gorski, M., McMahon, G. M., Xu, H., Chang, Y. P. C., Van Der Most, P. J., Navis, G., Nolte, I. M., De Borst, M. H., Zhang, W., Lehne, B., Loh, M., Tan, S. T., Boerwinkle, E., Grams, M. E., Sekula, P., Li, M., Wilmot, B., Moon, J. G., Scheet, P. & 86 others, Cucca, F., Xiao, X., Lyytikäinen, L. P., Delgado, G., Grammer, T. B., Kleber, M. E., Sedaghat, S., Rivadeneira, F., Corre, T., Kutalik, Z., Bergmann, S., Nielson, C. M., Srikanth, P., Teumer, A., Müller-Nurasyid, M., Brockhaus, A. C., Pfeufer, A., Rathmann, W., Peters, A., Matsumoto, M., De Andrade, M., Atkinson, E. J., Robinson-Cohen, C., De Boer, I. H., Hwang, S. J., Heid, I. M., Gögele, M., Concas, M. P., Tanaka, T., Bandinelli, S., Nalls, M. A., Singleton, A., Tajuddin, S. M., Adeyemo, A., Zhou, J., Doumatey, A., McWeeney, S., Murabito, J., Franceschini, N., Flessner, M., Shlipak, M., Wilson, J. G., Chen, G., Rotimi, C. N., Zonderman, A. B., Evans, M. K., Ferrucci, L., Devuyst, O., Pirastu, M., Shuldiner, A., Hicks, A. A., Pramstaller, P. P., Kestenbaum, B., Kardia, S. L. R., Turner, S. T., Study, L. C., Briske, T. E., Gieger, C., Strauch, K., Meisinger, C., Meitinger, T., Völker, U., Nauck, M., Völzke, H., Vollenweider, P., Bochud, M., Waeber, G., Kähönen, M., Lehtimäki, T., März, W., Dehghan, A., Franco, O. H., Uitterlinden, A. G., Hofman, A., Taylor, H. A., Chambers, J. C., Kooner, J. S., Fox, C. S., Hitzemann, R., Orwoll, E. S., Pattaro, C., Schlessinger, D., Köttgen, A., Snieder, H., Parsa, A. & Cohen, D. M., Aug 2017, In : Journal of the American Society of Nephrology. 28, 8, p. 2311-2321 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

The cumulative effects of intravenous antibiotic treatments on hearing in patients with cystic fibrosis

Garinis, A. C., Cross, C. P., Srikanth, P., Carroll, K., Feeney, M. P., Keefe, D. H., Hunter, L. L., Putterman, D. B., Cohen, D. M., Gold, J. A. & Steyger, P. S., May 2017, In : Journal of Cystic Fibrosis. 16, 3, p. 401-409 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Trends and characteristics of US Medicare spending on repository corticotropin

Hartung, D. M., Johnston, K., Van Leuven, S., Deodhar, A. A., Cohen, D. & Bourdette, D., Nov 1 2017, In : JAMA Internal Medicine. 177, 11, p. 1680-1682 3 p.

Research output: Contribution to journalArticle

9 Scopus citations
2016

Modeling the neurologic and cognitive effects of hyponatremia

Cohen, D., Mar 1 2016, In : Journal of the American Society of Nephrology. 27, 3, p. 659-661 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
2015

A mutation creating an out-of-frame alternative translation initiation site in the GRHPR 5′UTR causing primary hyperoxaluria type II

Fu, Y., Rope, R., Fargue, S., Cohen, H. T., Holmes, R. P. & Cohen, D. M., Nov 2015, In : Clinical Genetics. 88, 5, p. 494-498 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Potassium modulates electrolyte balance and blood pressure through effects on distal cell voltage and chloride

Terker, A. S., Zhang, C., McCormick, J. A., Lazelle, R. A., Zhang, C., Meermeier, N. P., Siler, D. A., Park, H. J., Fu, Y., Cohen, D. M., Weinstein, A. M., Wang, W. H., Yang, C. L. & Ellison, D. H., Jan 6 2015, In : Cell Metabolism. 21, 1, p. 39-50 12 p.

Research output: Contribution to journalArticle

173 Scopus citations
2014

Hourly oral sodium chloride for the rapid and predictable treatment of hyponatremia

Kerns, E., Patel, S. & Cohen, D. M., Jan 1 2014, In : Clinical Nephrology. 82, 6, p. 397-401 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Individuality of the plasma sodium concentration

Zhang, Z., Duckart, J., Slatore, C. G., Fu, Y., Petrik, A. F., Thorp, M. L. & Cohen, D. M., Jun 15 2014, In : American Journal of Physiology - Renal Physiology. 306, 12, p. F1534-F1543

Research output: Contribution to journalArticle

15 Scopus citations

Transcriptome-based analysis of kidney gene expression changes associated with diabetes in OVE26 mice, in the presence and absence of losartan treatment

Komers, R., Xu, B., Fu, Y., McClelland, A., Kantharidis, P., Mittal, A., Cohen, H. T. & Cohen, D. M., May 14 2014, In : PloS one. 9, 5, e96987.

Research output: Contribution to journalArticle

7 Scopus citations
2013

Candidate tumor suppressor and pVHL partner Jade-1 binds and inhibits AKT in renal cell carcinoma

Zeng, L., Bai, M., Mittal, A. K., El-Jouni, W., Zhou, J., Cohen, D. M., Zhou, M. I. & Cohen, H. T., Sep 1 2013, In : Cancer Research. 73, 17, p. 5371-5380 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
4 Scopus citations
2012

Heritability of serum sodium concentration: Evidence for sex- and ethnic-specific effects

Wilmot, B., Saroja Voruganti, V., Chang, Y. P. C., Fu, Y., Chen, Z., Taylor, H. A., Wilson, J. G., Gipson, T., Shah, V. O., Umans, J. G., Flessner, M. F., Hitzemann, R., Shuldiner, A. R., Comuzzie, A. G., Mcweeney, S., Zager, P. G., Maccluer, J. W., Cole, S. A. & Cohen, D. M., Feb 1 2012, In : Physiological genomics. 44, 3, p. 220-228 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
2011

African American living-kidney donors should be screened for apol1 risk alleles

Cohen, D. M., Mittalhenkle, A., Scott, D. L., Young, C. J. & Norman, D. J., Oct 15 2011, In : Transplantation. 92, 7, p. 722-725 4 p.

Research output: Contribution to journalArticle

43 Scopus citations
2010

Absence of AVPR2 copy number variation in eunatremic and dysnatremic subjects in non-Hispanic Caucasian populations

Fu, Y., Chen, Z., Blakemore, A. I. F., Orwoll, E. & Cohen, D. M., Feb 1 2010, In : Physiological genomics. 40, 3, p. 121-127 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice

Ceppa, E., Cattaruzza, F., Lyo, V., Amadesi, S., Pelayo, J. C., Poole, D. P., Vaksman, N., Liedtke, W., Cohen, D. M., Grady, E. F., Bunnett, N. W. & Kirkwood, K. S., Sep 1 2010, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 299, 3, p. G556-G571

Research output: Contribution to journalArticle

64 Scopus citations
2009

A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia

Tian, W., Fu, Y., Garcia-Elias, A., Fernández-Fernández, J. M., Vicente, R., Kramer, P. L., Klein, R. F., Hitzemann, R., Orwoll, E. S., Wilmot, B., McWeeney, S., Valverde, M. A. & Cohen, D. M., Aug 18 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 33, p. 14034-14039 6 p.

Research output: Contribution to journalArticle

68 Scopus citations

Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion

Fu, Y., Tian, W., Pratt, E. B., Dirling, L. B., Shyng, S. L., Meshul, C. K. & Cohen, D. M., May 25 2009, In : PloS one. 4, 5, e5679.

Research output: Contribution to journalArticle

59 Scopus citations
2008

Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia

Sipe, W. E. B., Brierley, S. M., Martin, C. M., Phillis, B. D., Cruz, F. B., Grady, E. F., Liedtke, W., Cohen, D. M., Vanner, S., Blackshaw, L. A. & Bunnett, N. W., May 1 2008, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 294, 5, p. G1288-G1298

Research output: Contribution to journalArticle

107 Scopus citations

TRPV4 enhances the cellular uptake of aminoglycoside antibiotics

Karasawa, T., Wang, Q., Fu, Y., Cohen, D. M. & Steyger, P. S., Sep 1 2008, In : Journal of Cell Science. 121, 17, p. 2871-2879 9 p.

Research output: Contribution to journalArticle

53 Scopus citations

White thrombus formation in blood tubing lines in a chronic hemodialysis unit

Watnick, S., Stooksbury, M., Winter, R., Riscoe, M. & Cohen, D. M., Mar 1 2008, In : Clinical Journal of the American Society of Nephrology. 3, 2, p. 382-386 5 p.

Research output: Contribution to journalArticle

5 Scopus citations
2007

Functional effects of nonsynonymous polymorphisms in the human TRPV1 gene

Xu, H., Tian, W., Fu, Y., Oyama, T. T., Anderson, S. & Cohen, D. M., Dec 1 2007, In : American Journal of Physiology - Renal Physiology. 293, 6, p. F1865-F1876

Research output: Contribution to journalArticle

51 Scopus citations

Renal p38 MAP kinase activity in experimental diabetes

Komers, R., Lindsley, J. N., Oyama, T. T., Cohen, D. M. & Anderson, S., Jun 1 2007, In : Laboratory Investigation. 87, 6, p. 548-558 11 p.

Research output: Contribution to journalArticle

35 Scopus citations
2006
57 Scopus citations

Regulation of TRPV1 by a novel renally expressed rat TRPV1 splice variant

Tian, W., Fu, Y., Wang, D. H. & Cohen, D. M., Jan 1 2006, In : American Journal of Physiology - Renal Physiology. 290, 1, p. F117-F126

Research output: Contribution to journalArticle

35 Scopus citations

The role of MAPKs in B cell receptor-induced down-regulation of Egr-1 in immature B lymphoma cells

Ke, J., Gururajan, M., Kumar, A., Simmons, A., Turcios, L., Chelvarajan, R. L., Cohen, D. M., Wiest, D. L., Monroe, J. G. & Bondada, S., Dec 29 2006, In : Journal of Biological Chemistry. 281, 52, p. 39806-39818 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

WNK kinases influence TRPV4 channel function and localization

Fu, Y., Subramanya, A., Rozansky, D. & Cohen, D. M., Jun 1 2006, In : American Journal of Physiology - Renal Physiology. 290, 6, p. F1305-F1314

Research output: Contribution to journalArticle

68 Scopus citations
2005

EphA2: Expression in the renal medulla and regulation by hypertonicity and urea stress in vitro and in vivo

Xu, H., Tian, W., Lindsley, J. N., Oyama, T. T., Capasso, J. M., Rivard, C. J., Cohen, H. T., Bagnasco, S. M., Anderson, S. & Cohen, D. M., Apr 1 2005, In : American Journal of Physiology - Renal Physiology. 288, 4 57-4, p. F855-F866

Research output: Contribution to journalArticle

19 Scopus citations

Interleukin-10 suppresses tissue factor expression in lipopolysaccharide- stimulated macrophages via inhibition of Egr-1 and a serum response element/MEK-ERK1/2 pathway

Kamimura, M., Viedt, C., Dalpke, A., Rosenfeld, M. E., Mackman, N., Cohen, D. M., Blessing, E., Preusch, M., Weber, C. M., Kreuzer, J., Katus, H. A. & Bea, F., Aug 19 2005, In : Circulation research. 97, 4, p. 305-313 9 p.

Research output: Contribution to journalArticle

40 Scopus citations
2004

Renal expression of osmotically responsive cation channel TRPV4 is restricted to water-impermeant nephron segments

Tian, W., Salanova, M., Xu, H., Lindsley, J. N., Oyama, T. T., Anderson, S., Bachmann, S. & Cohen, D. M., Jul 1 2004, In : American Journal of Physiology - Renal Physiology. 287, 1 56-1, p. F17-F24

Research output: Contribution to journalArticle

104 Scopus citations
2003

Hypertonic induction of COX-2 expression in renal medullary epithelial cells requires transactivation of the EGFR

Zhao, H., Tian, W., Tai, C. & Cohen, D. M., Aug 1 2003, In : American Journal of Physiology - Renal Physiology. 285, 2 54-2, p. F281-F288

Research output: Contribution to journalArticle

34 Scopus citations
149 Scopus citations

Urea signalling to immediate-early gene transcription in renal medullary cells requires transactivation of the epidermal growth factor receptor

Zhao, H., Tian, W., Xu, H. & Cohen, D. M., Mar 1 2003, In : Biochemical Journal. 370, 2, p. 479-487 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
2002

Effects of cyclooxygenase-2 (COX-2) inhibition on plasma and renal renin in diabetes

Komers, R., Tian, W., Lindsley, J. N., Oyama, T. T., Cohen, D. M. & Anderson, S., Nov 1 2002, In : Journal of Laboratory and Clinical Medicine. 140, 5, p. 351-357 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Rottlerin inhibits tonicity-dependent expression and action of TonEBP in a PKCδ-independent fashion

Zhao, H., Tian, W. & Cohen, D. M., Jun 29 2002, In : American Journal of Physiology - Renal Physiology. 282, 4 51-4, p. F710-F717

Research output: Contribution to journalArticle

22 Scopus citations

Urea stress is more akin to EGF exposure than to hypertonic stress in renal medullary cells

Tian, W. & Cohen, D. M., Sep 1 2002, In : American Journal of Physiology - Renal Physiology. 283, 3 52-3, p. F388-F398

Research output: Contribution to journalArticle

21 Scopus citations
2001

Activation of Elk-1, an Ets transcription factor, by glucose and EGF treatment of insulinoma cells

Bernal-Mizrachi, E., Wen, W., Srinivasan, S., Klenk, A., Cohen, D. & Alan Permutt, M., Dec 1 2001, In : American Journal of Physiology - Endocrinology and Metabolism. 281, 6 44-6, p. E1286-E1299

Research output: Contribution to journalArticle

36 Scopus citations
18 Scopus citations

Urea and hypertonicity increase expression of heme oxygenase-1 in murine renal medullary cells

Tian, W., Bonkovsky, H. L., Shibahara, S. & Cohen, D. M., Dec 19 2001, In : American Journal of Physiology - Renal Physiology. 281, 5 50-5, p. F983-F991

Research output: Contribution to journalArticle

24 Scopus citations

Urea inhibits hypertonicity-inducible TonEBP expression and action

Tian, W. & Cohen, D. M., May 1 2001, In : American Journal of Physiology - Renal Physiology. 280, 5 49-5, p. F904-F912

Research output: Contribution to journalArticle

22 Scopus citations

Urea signaling to ERK phosphorylation in renal medullary cells requires extracellular calcium but not calcium entry

Yang, X. Y., Zhao, H., Zhang, Z., Rodland, K. D., Roullet, J. B. & Cohen, D. M., Jan 1 2001, In : American Journal of Physiology - Renal Physiology. 280, 1 49-1, p. F162-F171

Research output: Contribution to journalArticle

2 Scopus citations
2000

Pi3K signaling in the murine kidney inner medullary cell response to urea

Zhang, Z., Yang, X. Y., Soltoff, S. P. & Cohen, D. M., Jan 1 2000, In : American Journal of Physiology - Renal Physiology. 278, 1 47-1, p. F155-F164

Research output: Contribution to journalArticle

32 Scopus citations
6 Scopus citations

Ras signaling in the inner medullary cell response to urea and NaCl

Tian, W., Boss, G. R. & Cohen, D. M., Mar 15 2000, In : American Journal of Physiology - Cell Physiology. 278, 2 47-2, p. C372-C380

Research output: Contribution to journalArticle

30 Scopus citations

Urea protects from the proapoptotic effect of NaCl in renal medullary cells

Zhang, Z., Wei, T. & Cohen, D. M., Sep 18 2000, In : American Journal of Physiology - Renal Physiology. 279, 2 48-2, p. F345-F352

Research output: Contribution to journalArticle

35 Scopus citations
1999

ERK activation by urea in the renal inner medullary mIMCD3 cell line

Yang, X. Y., Zhang, Z. & Cohen, D. M., Aug 1 1999, In : American Journal of Physiology - Renal Physiology. 277, 2 46-2, p. F176-F185

Research output: Contribution to journalArticle

24 Scopus citations

Hypoxia-associated induction of early growth response-1 gene expression

Yan, S. F., Lu, J., Zou, Y. S., Soh-Won, J., Cohen, D. M., Buttrick, P. M., Cooper, D. R., Steinberg, S. F., Mackman, N., Pinsky, D. J. & Stern, D. M., May 21 1999, In : Journal of Biological Chemistry. 274, 21, p. 15030-15040 11 p.

Research output: Contribution to journalArticle

211 Scopus citations