Daniel Tshala-Katumbay

Associate Professor

  • 531 Citations
  • 15 h-Index
19992019

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Article
2018

Dietary cyanogen exposure and early child neurodevelopment: An observational study from the Democratic Republic of Congo

Kashala-Abotnes, E., Sombo, M. T., Okitundu, D. L., Kunyu, M., Makila-Mabe, G. B., Tylleskär, T., Sikorskii, A., Banea, J. P., Ngoyi, D. M., Tshala-Katumbay, D. & Boivin, M. J., Apr 2018, In : PloS one. 13, 4, e0193261.

Research output: Contribution to journalArticle

4 Scopus citations

Heart Failure Etiologies and Challenges to Care in the Developing World: An Observational Study in the Democratic Republic of Congo

Malamba-Lez, D., Ngoy-Nkulu, D., Steels, P., Tshala-Katumbay, D. & Mullens, W., Jan 1 2018, (Accepted/In press) In : Journal of Cardiac Failure.

Research output: Contribution to journalArticle

7 Scopus citations
1 Scopus citations

Troubles socio-émotionnels de l’enfant en milieu konzo, un syndrome paralytique de nature épidémique associé à une intoxication cyanhydrique d’origine alimentaire en afrique sub-Saharienne

Translated title of the contribution: Socioemotional disorders in children living in Konzo-affected areas, an epidemic paralytic disease associated with cyanide poisoning from food in sub-Saharan AfricaE-Andjafono, D. O. L., Ayanne, M. T. S. S., Makila-Mabe, G. B., Mayambu, J. P. B., Ngoyi, D. M., Boivin, M., Tamfum-Muyembe, J. J. & Tshala-Katumbay, D., Jan 1 2018, In : Pan African Medical Journal. 31, 118.

Research output: Contribution to journalArticle

Open Access
2017

Cognitive and motor performance in Congolese children with konzo during 4 years of follow-up: a longitudinal analysis

Boivin, M. J., Okitundu, D., Makila-Mabe, B., Sombo, M. T., Mumba, D., Sikorskii, A., Mayambu, B. & Tshala-Katumbay, D., Sep 2017, In : The Lancet Global Health. 5, 9, p. e936-e947

Research output: Contribution to journalArticle

5 Scopus citations

Comparison of metabolic profiles and bioactivities of the leaves of three edible Congolese Hibiscus species

Kapepula, P. M., Kabamba Ngombe, N., Tshisekedi Tshibangu, P., Tsumbu, C., Franck, T., Mouithys-Mickalad, A., Mumba, D., Tshala-Katumbay, D., Serteyn, D., Tits, M., Angenot, L., Kalenda, P. D. T. & Frédérich, M., Dec 17 2017, In : Natural Product Research. 31, 24, p. 2885-2892 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Lower sulfurtransferase detoxification rates of cyanide in konzo—A tropical spastic paralysis linked to cassava cyanogenic poisoning

Kambale, K. J., Ali, E. R., Sadiki, N. H., Kayembe, K. P., Mvumbi, L. G., Yandju, D. L., Boivin, M. J., Boss, G. R., Stadler, D. D., Lambert, W. E., Lasarev, M. R., Okitundu, L. A., Mumba Ngoyi, D., Banea, J. P. & Tshala-Katumbay, D. D., Mar 1 2017, In : NeuroToxicology. 59, p. 256-262 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
2016

Cyanide and the human brain: perspectives from a model of food (cassava) poisoning

Tshala-Katumbay, D., Ngombe, N. N., Okitundu, D., David, L., Westaway, S., Boivin, M. J., Mumba, N. D. & Banea, J. P., Aug 1 2016, In : Annals of the New York Academy of Sciences. 1378, 1, p. 50-57 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Lead exposure and early child neurodevelopment among children 12–24 months in Kinshasa, the Democratic Republic of Congo

Kashala-Abotnes, E., Mumbere, P. P., Mishika, J. M., Ndjukendi, A. O., Mpaka, D. B., Bumoko, M. M. G., Kayembe, T. K., Tshala-Katumbay, D., Kazadi, T. K. & Okitundu, D. L. E. A., Dec 1 2016, In : European Child and Adolescent Psychiatry. 25, 12, p. 1361-1367 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
2015

Konzo prevention in six villages in the DRC and the dependence of konzo prevalence on cyanide intake and malnutrition

Banea, J. P., Bradbury, J. H., Mandombi, C., Nahimana, D., Denton, I. C., Foster, M. P., Kuwa, N. & Tshala Katumbay, D., Apr 7 2015, In : Toxicology Reports. 2, p. 609-616 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Living with epilepsy in Lubumbashi (Democratic Republic Of Congo): Epidemiology, risk factors and treatment gap

Koba Bora, B., Lez, D. M., Luwa, D. O., Baguma, M. B., Katumbay, D. T., Kalula, T. K. & Kabwa, P. L. M., Aug 26 2015, In : Pan African Medical Journal. 21, 303.

Research output: Contribution to journalArticle

7 Scopus citations

Lower serum levels of selenium, copper, and zinc are related to neuromotor impairments in children with konzo

Bumoko, G. M. M., Sadiki, N. H., Rwatambuga, A., Kayembe, K. P., Okitundu, D. L., Mumba Ngoyi, D., Muyembe, J. J. T., Banea, J. P., Boivin, M. J. & Tshala-Katumbay, D., Feb 15 2015, In : Journal of the neurological sciences. 349, 1-2, p. 149-153 5 p.

Research output: Contribution to journalArticle

15 Scopus citations
2014

Cross-species and tissue variations in cyanide detoxification rates in rodents and non-human primates on protein-restricted diet

Kimani, S., Moterroso, V., Morales, P., Wagner, J., Kipruto, S., Bukachi, F., Maitai, C. & Tshala-Katumbay, D., Apr 1 2014, In : Food and Chemical Toxicology. 66, p. 203-209 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Determinants of cognitive performance in children relying on cyanogenic cassava as staple food

Bumoko, G. M., Sombo, M. T., Okitundu, L. D., Mumba, D. N., Kazadi, K. T., Tamfum-Muyembe, J. J., Lasarev, M. R., Boivin, M. J., Banea, J. P. & Tshala-Katumbay, D. D., Jun 2014, In : Metabolic brain disease. 29, 2, p. 359-366 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Effectiveness of wetting method for control of konzo and reduction of cyanide poisoning by removal of cyanogens from cassava flour

Banea, J. P., Bradbury, J. H., Mandombi, C., Nahimana, D., Denton, I. C., Kuwa, N. & Tshala Katumbay, D., Mar 1 2014, In : Food and Nutrition Bulletin. 35, 1, p. 28-32 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Memory deficits associated with sublethal cyanide poisoning relative to cyanate toxicity in rodents

Kimani, S., Sinei, K., Bukachi, F., Tshala-Katumbay, D. & Maitai, C., Mar 2014, In : Metabolic brain disease. 29, 1, p. 105-112 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Persistance des épidémies de konzo à kahemba, république démocratique du congo: Aspects phénoménologiques et socio-économiques

Translated title of the contribution: Persistence epidemics konzo to kahemba, democratic republic of congo: Phenomenological aspects and socio-economicE-Andjafono, D. O. L., Makila-Mabe, G. B., Ayanne, M. T. S. S., Kikandau, J. K., Mashukano, N., Kazembe, T. K., Ngoyi, D. M., Boivin, M. J., Tamfum-Muyembe, J. J., Mayambu, J. P. B. & Tshala-Katumbay, D., 2014, In : Pan African Medical Journal. 18, 213.

Research output: Contribution to journalArticle

4 Scopus citations

Serum 8,12-iso-iPF2α-VI isoprostane marker of oxidative damage and cognition deficits in children with konzo

Makila-Mabe, B. G., Kikandau, K. J., Sombo, T. M., Okitundu, D. L., Mwanza, J. C., Boivin, M. J., Ngoyi, M. D., Muyembe, J. J. T., Banea, J. P., Boss, G. R. & Tshala-Katumbay, D., Sep 15 2014, In : PloS one. 9, 9, e107191.

Research output: Contribution to journalArticle

12 Scopus citations
2013

Carbamoylation correlates of cyanate neuropathy and cyanide poisoning: Relevance to the biomarkers of cassava cyanogenesis and motor system toxicity

Kimani, S., Moterroso, V., Lasarev, M., Kipruto, S., Bukachi, F., Maitai, C., David, L. & Tshala-Katumbay, D., Jan 1 2013, In : SpringerPlus. 2, 1, p. 1-8 8 p., 647.

Research output: Contribution to journalArticle

10 Scopus citations

Control of konzo by detoxification of cassava flour in three villages in the Democratic Republic of Congo

Banea, J. P., Bradbury, J. H., Mandombi, C., Nahimana, D., Denton, I. C., Kuwa, N. & Tshala Katumbay, D., Oct 1 2013, In : Food and Chemical Toxicology. 60, p. 506-513 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Diagnostic and therapeutic potential of tetanus toxin-derivatives in neurological diseases

Kassa, R., Monterroso, V., David, L. L. & Tshala-Katumbay, D., Nov 1 2013, In : Journal of Molecular Neuroscience. 51, 3, p. 788-791 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Neuropsychological effects of konzo: A neuromotor disease associated with poorly processed cassava

Boivin, M. J., Okitundu, D., Bumoko, G. M. M., Sombo, M. T., Mumba, D., Tylleskar, T., Page, C. F., Muyembe, J. J. T. & Tshala-Katumbay, D., Apr 2013, In : Pediatrics. 131, 4, p. e1231-e1239

Research output: Contribution to journalArticle

30 Scopus citations
2012

Prothrombin G20210A and factor V Leiden polymorphisms in stroke

They-They, T. P., Battas, O., Slassi, I., Rafai, M. A., Katumbay, D. T. & Nadifi, S., Feb 2012, In : Journal of Molecular Neuroscience. 46, 1, p. 210-216 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Proximal giant neurofilamentous axonopathy in mice genetically engineered to resist calpain and caspase cleavage of α-II spectrin

Kassa, R., Monterroso, V., Wentzell, J., Ramos, A. L., Couchi, E., Lecomte, M. C., Iordanov, M., Kretzschmar, D., Nicolas, G. & Tshala-Katumbay, D., Jul 1 2012, In : Journal of Molecular Neuroscience. 47, 3, p. 631-638 8 p.

Research output: Contribution to journalArticle

2 Scopus citations
2011

On the biomarkers and mechanisms of konzo, a distinct upper motor neuron disease associated with food (cassava) cyanogenic exposure

Kassa, R. M., Kasensa, N. L., Monterroso, V. H., Kayton, R. J., Klimek, J. E., David, L. L., Lunganza, K. R., Kayembe, K. T., Bentivoglio, M., Juliano, S. L. & Tshala-Katumbay, D. D., Mar 1 2011, In : Food and Chemical Toxicology. 49, 3, p. 571-578 8 p.

Research output: Contribution to journalArticle

23 Scopus citations
2009

New insights into mechanisms of γ-Diketone-induced axonopathy

Tshala-Katumbay, D., Desjardins, P., Sabri, M., Butterworth, R. & Spencer, P., Apr 30 2009, In : Neurochemical Research. 34, 11, p. 1919-1923 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Probing mechanisms of axonopathy. Part II: Protein targets of 2,5-Hexanedione, the neurotoxic metabolite of the aliphatic solvent n-Hexane

Tshala-Katumbay, D., Monterroso, V., Kayton, R., Lasarev, M., Sabri, M. & Spencer, P., 2009, In : Toxicological Sciences. 107, 2, p. 482-489 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
2008

Probing mechanisms of axonopathy. Part I: Protein targets of 1,2-diacetylbenzene, the neurotoxic metabolite of aromatic solvent 1,2-diethylbenzene

Tshala-Katumbay, D., Monterroso, V., Kayton, R., Lasarev, M., Sabri, M. & Spencer, P., 2008, In : Toxicological Sciences. 105, 1, p. 134-141 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
2006

Monocyclic and dicyclic hydrocarbons: Structural requirements for proximal giant axonopathy

Tshala-Katumbay, D. D., Palmer, V. S., Lasarev, M. R., Kayton, R. J., Sabri, M. I. & Spencer, P. S., Sep 1 2006, In : Acta Neuropathologica. 112, 3, p. 317-324 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
2005

A new murine model of giant proximal axonopathy

Tshala-Katumbay, D. D., Palmer, V. S., Kayton, R. J., Sabri, M. I. & Spencer, P. S., Apr 1 2005, In : Acta Neuropathologica. 109, 4, p. 405-410 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Neuro-ophthalmologic manifestations of konzo

Mwanza, J. C., Tshala-Katumbay, D. & Tylleskär, T., May 2005, In : Environmental Toxicology and Pharmacology. 19, 3, p. 491-496 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
2004

Konzo

Edebol Eeg-Olofsson, K. & Tshala-Katumbay, D., Dec 1 2004, In : Handbook of Clinical Neurophysiology. 4, C, p. 675-686 12 p.

Research output: Contribution to journalArticle

1 Scopus citations
2003

Neuro-ophthalmologic findings in konzo, an upper motor neuron disorder in Africa

Mwanza, J. C. K., Tshala-Katumbay, D., Kayembe, D. L., Eeg-Olofsson, K. E. & Tylleskär, T., May 2003, In : European journal of ophthalmology. 13, 4, p. 383-389 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Visual evoked potentials in konzo, a spastic paraparesis of acute onset in Africa

Mwanza, J. C., Lysebo, D. E., Kayembe, D. L., Tshala-Katumbay, D., Nyamabo, L. K., Tylleskär, T. & Plant, G. T., 2003, In : Ophthalmologica. 217, 6, p. 381-386 6 p.

Research output: Contribution to journalArticle

17 Scopus citations
2002

Abnormalities of somatosensory evoked potentials in konzo - An upper motor neuron disorder

Tshala-Katumbay, D., Edebol Eeg-Olofsson, K., Kazadi-Kayembe, T., Fällmar, P., Tylleskär, T. & Kayembe-Kalula, T., Feb 5 2002, In : Clinical Neurophysiology. 113, 1, p. 10-15 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Analysis of motor pathway involvement in konzo using transcranial electrical and magnetic stimulation

Tshala-Katumbay, D., Eeg-Olofsson, K. E., Kazadi-Kayembe, T., Tylleskär, T. & Fällmar, P., Feb 12 2002, In : Muscle and Nerve. 25, 2, p. 230-235 6 p.

Research output: Contribution to journalArticle

29 Scopus citations
2001

Impairments, disabilities and handicap pattern in konzo - A non-progressive spastic para/tetraparesis of acute onset

Tshala-Katumbay, D., Eeg-olofsson, K. E., Tylleskär, T. & Kazadi-Kayembe, T., Nov 10 2001, In : Disability and Rehabilitation. 23, 16, p. 731-736 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Neuroepidemiology of konzo a spastic para-tetraparesis of acute onset in a new area of the Democratic Republic of Congo

Tshala-Katumbay, D., Banea-Mayambu, J. P., Kazadi-Kayembe, T., Nunga-Matadi, R., Bikangi-Nkiabungu, F., Edebol Eeg-Olofsson, K. & Tylleskär, T., Dec 1 2001, In : African Journal of Neurological Sciences. 20, 1

Research output: Contribution to journalArticle

17 Scopus citations
2000

EEG Findings in Konzo: A Spastic Para/Tetraparesis of Acute Onset

Katumbay, D. T., Lukusa, V. M. & Eeg-Olofsson, K. E., Oct 2000, In : Clinical EEG and Neuroscience. 31, 4, p. 196-200 5 p.

Research output: Contribution to journalArticle

20 Scopus citations
1999

Coexistence hysterie collective, konzo et virus HTLV-1 en republique democratique du congo

Translated title of the contribution: Mass hysteria, konzo, and HTLV-1 virus in the democratic republic of congoTshala, K., Dec 1 1999, In : Medecine Tropicale. 59, 4, p. 378-382 5 p.

Research output: Contribution to journalArticle

4 Scopus citations