Charles Roselli

Professor

  • 4984 Citations
  • 40 h-Index
1978 …2018
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Research Output 1980 2018

  • 4984 Citations
  • 40 h-Index
  • 123 Article
  • 1 Chapter
  • 1 Conference contribution
  • 1 Review article
2018

Early prenatal androgen exposure reduces testes size and sperm concentration in sheep without altering neuroendocrine differentiation and masculine sexual behavior

Scully, C. M., Estill, C. T., Amodei, R., McKune, A., Gribbin, K. P., Meaker, M., Stormshak, F. & Roselli, C. E., Jan 1 2018, In : Domestic Animal Endocrinology. 62, p. 1-9 9 p.

Research output: Contribution to journalArticle

sperm concentration
sexual behavior
Spermatogenesis
First Pregnancy Trimester
androgens
2017
2 Citations

Fos expression in the olfactory pathway of high- and low-sexually performing rams exposed to urine from estrous or ovariectomized ewes

Mirto, A. J., Austin, K. J., Uthlaut, V. A., Roselli, C. E. & Alexander, B. M., Jan 1 2017, In : Applied Animal Behaviour Science. 186, p. 22-28 7 p.

Research output: Contribution to journalArticle

Olfactory Pathways
rams
ewes
urine
Urine
1 Citations

Tyrosine hydroxylase in the ventral tegmental area of rams with high or low libido—A role for dopamine

Kramer, A. C., Mirto, A. J., Austin, K. J., Roselli, C. E. & Alexander, B. M., Dec 1 2017, In : Animal Reproduction Science. 187, p. 152-158 7 p.

Research output: Contribution to journalArticle

tyrosine 3-monooxygenase
libido
Libido
Ventral Tegmental Area
Tyrosine 3-Monooxygenase
2016
5 Citations

Developmental and Functional Effects of Steroid Hormones on the Neuroendocrine Axis and Spinal Cord

Zubeldia-Brenner, L., Roselli, C. E., Recabarren, S. E., Gonzalez Deniselle, M. C. & Lara, H. E., Jul 1 2016, In : Journal of Neuroendocrinology. 28, 7

Research output: Contribution to journalReview article

Spinal Cord
Estrogens
Steroids
Hormones
Prolactinoma
1 Citations

Effects of Long-Term Flutamide Treatment During Development on Sexual Behaviour and Hormone Responsiveness in Rams

Roselli, C. E., Meaker, M., Stormshak, F. & Estill, C. T., May 1 2016, In : Journal of Neuroendocrinology. 28, 5

Research output: Contribution to journalArticle

Flutamide
Sexual Behavior
Hormones
Androgens
Sheep
1 Citations

Excess testosterone exposure alters hypothalamic-pituitary-Testicular axis dynamics and gene expression in sheep fetuses

Roselli, C. E., Amodei, R., Gribbin, K. P., Corder, K., Stormshak, F. & Estill, C. T., Nov 1 2016, In : Endocrinology. 157, 11, p. 4234-4245 12 p.

Research output: Contribution to journalArticle

Gonadotropins
Testosterone
Sheep
Fetus
Kisspeptins
2015
2 Citations

Effect of testosterone on neuronal morphology and neuritic growth of fetal lamb hypothalamus-preoptic area and cerebral cortex in primary culture

Reddy, R. C., Amodei, R., Estill, C. T., Stormshak, F., Meaker, M. & Roselli, C. E. R., Jun 8 2015, In : PLoS One. 10, 6

Research output: Contribution to journalArticle

preoptic area
Preoptic Area
cerebral cortex
fetal development
hypothalamus
2014
2 Citations

Cell death in the central division of the medial preoptic nucleus of male and female lamb fetuses

Reddy, R. C., Scheldrup, M., Meaker, M., Stormshak, F., Estill, C. T. & Roselli, C. E., Mar 20 2014, In : Brain Research. 1554, p. 21-28 8 p.

Research output: Contribution to journalArticle

Preoptic Area
Sheep
Fetus
Cell Death
bcl-2 Genes
6 Citations

Prenatal influence of an androgen agonist and antagonist on the differentiation of the ovine sexually dimorphic nucleus in male and female lamb fetuses

Roselli, C. E., Reddy, R. C., Estill, C. T., Scheldrup, M., Meaker, M., Stormshak, F. & Montilla, H. J., Dec 1 2014, In : Endocrinology. 155, 12, p. 5000-5010 11 p.

Research output: Contribution to journalArticle

Androgen Antagonists
Flutamide
Sheep
Fetus
Dihydrotestosterone
6 Citations

Sex differences in expression of oestrogen receptor α but not androgen receptor mRNAs in the foetal lamb brain

Reddy, R. C., Estill, C. T., Meaker, M., Stormshak, F. & Roselli, C. E., 2014, In : Journal of Neuroendocrinology. 26, 5, p. 321-328 8 p.

Research output: Contribution to journalArticle

Estrogen Receptor alpha
Androgen Receptors
Sex Characteristics
Messenger RNA
Sheep
2013
12 Citations

Neonatal testosterone exposure protects adult male rats from stroke

Persky, R. W., Liu, F., Xu, Y., Weston, G., Levy, S., Roselli, C. E. & McCullough, L. D., Apr 2013, In : Neuroendocrinology. 97, 3, p. 271-282 12 p.

Research output: Contribution to journalArticle

Testosterone
Testosterone Propionate
Stroke
Oils
Androgens
1 Citations
Estradiol
Estrogens
Membranes
Sexual Behavior
Estrogen Receptors
1 Citations

The Distribution and Regulation of Aromatase in the Mammalian Brain: from Mice to Monkeys

Roselli, C. E. Jan 24 2013 Brain Aromatase, Estrogens, and Behavior. Oxford University Press

Research output: Chapter in Book/Report/Conference proceedingChapter

Aromatase
Haplorhini
Estrogens
Brain
Gonads
2012
8 Citations

Ontogeny of Cytochrome P450 Aromatase mRNA Expression in the Developing Sheep Brain

Roselli, C. E. & Stormshak, F., Mar 2012, In : Journal of Neuroendocrinology. 24, 3, p. 443-452 10 p.

Research output: Contribution to journalArticle

Aromatase
Cytochrome P-450 Enzyme System
Sheep
Messenger RNA
Brain
2011
2 Citations

Localization of brain 5α-reductase messenger RNA in mice selectively bred for high chronic alcohol withdrawal severity

Roselli, C. E., Finn, T. J., Ronnekleiv-Kelly, S. M., Tanchuck, M. A., Kaufman, K. R. & Finn, D. A., Dec 2011, In : Alcohol. 45, 8, p. 763-772 10 p.

Research output: Contribution to journalArticle

Pregnanolone
withdrawal
Brain
Oxidoreductases
brain
24 Citations

Separate critical periods exist for testosterone-induced differentiation of the brain and genitals in sheep

Roselli, C. E., Estill, C. T., Stadelman, H. L., Meaker, M. & Stormshak, F., Jun 2011, In : Endocrinology. 152, 6, p. 2409-2415 7 p.

Research output: Contribution to journalArticle

Testosterone Propionate
Testosterone
Sheep
Preoptic Area
Brain
2 Citations

Sexual differentiation of sexual behavior and its orientation

Roselli, C. & Balthazart, J. Apr 2011 In : Frontiers in Neuroendocrinology. 32, 2, p. 109 1 p.

Research output: Contribution to journalArticle

Animal Sexual Behavior
Sex Differentiation
Sexual Behavior
23 Citations

The development of male-oriented behavior in rams

Roselli, C. E., Reddy, R. C. & Kaufman, K. R., Apr 2011, In : Frontiers in Neuroendocrinology. 32, 2, p. 164-169 6 p.

Research output: Contribution to journalArticle

Sexual Partners
Marriage
Sheep
Hormones
Population
10 Citations

Wired on steroids: Sexual differentiation of the brain and its role in the expression of sexual partner preferences

Alexander, B. M., Skinner, D. C. & Roselli, C. E., 2011, In : Frontiers in Endocrinology. 2, OCT, Article 42

Research output: Contribution to journalArticle

Sex Differentiation
Sexual Partners
Steroids
Brain
Safe Sex
2010
44 Citations

Cognition is not modified by large but temporary changes in sex hormones in men

Young, L. A., Neiss, M. B., Samuels, M. H., Roselli, C. E. & Janowsky, J. S., Jan 2010, In : Journal of Clinical Endocrinology and Metabolism. 95, 1, p. 280-288 9 p.

Research output: Contribution to journalArticle

Gonadal Steroid Hormones
Cognition
Testosterone
Estradiol
Hypogonadism
5 Citations

Prenatal exposure to vinclozolin disrupts selective aspects of the gonadotrophin-releasing hormone neuronal system of the rabbit

Wadas, B. C., Hartshorn, C. A., Aurand, E. R., Palmer, J. S., Roselli, C. E., Noel, M. L., Gore, A. C., Veeramachaneni, D. N. R. & Tobet, S. A., 2010, In : Journal of Neuroendocrinology. 22, 6, p. 518-526 9 p.

Research output: Contribution to journalArticle

vinclozolin
Gonadotropin-Releasing Hormone
Rabbits
Flutamide
Median Eminence
14 Citations

The ovine sexually dimorphic nucleus, aromatase, and sexual partner preferences in sheep

Roselli, C. E. & Stormshak, F., Feb 28 2010, In : Journal of Steroid Biochemistry and Molecular Biology. 118, 4-5, p. 252-256 5 p.

Research output: Contribution to journalArticle

Aromatase
Sexual Partners
Testosterone
Sheep
Neurons
2009
30 Citations

Age-dependent effects of testosterone in experimental stroke

Cheng, J., Hu, W., Toung, T. J., Zhang, Z., Parker, S. M., Roselli, C. E. & Hurn, P. D., 2009, In : Journal of Cerebral Blood Flow and Metabolism. 29, 3, p. 486-494 9 p.

Research output: Contribution to journalArticle

Testosterone
Stroke
Aromatase
Young Adult
Androgen Receptor Antagonists
89 Citations

Brain aromatization: Classic roles and new perspectives

Roselli, C. E., Liu, M. & Hurn, P. D., May 2009, In : Seminars in Reproductive Medicine. 27, 3, p. 207-217 11 p.

Research output: Contribution to journalArticle

Brain
Sex Differentiation
Aromatase
Neurogenesis
Gonadotropins
24 Citations

Curcumin blocks CCL2-induced adhesion, motility and invasion, in part, through down-regulation of CCL2 expression and proteolytic activity

Herman, J. G., Stadelman, H. L. & Roselli, C. E., 2009, In : International Journal of Oncology. 34, 5, p. 1319-1327 9 p.

Research output: Contribution to journalArticle

Curcumin
Down-Regulation
Ligands
Prostatic Neoplasms
Protein Kinase C
22 Citations

Porcine hypothalamic aromatase cytochrome P450: Isoform characterization, sex-dependent activity, regional expression, and regulation by enzyme inhibition in neonatal boars

Corbin, C. J., Berger, T., Ford, J. J., Roselli, C. E., Sienkiewicz, W., Trainor, B. C., Roser, J. F., Vidal, J. D., Harada, N. & Conley, A. J., Aug 2009, In : Biology of Reproduction. 81, 2, p. 388-395 8 p.

Research output: Contribution to journalArticle

Aromatase
Cytochrome P-450 Enzyme System
Hypothalamus
Protein Isoforms
Swine
14 Citations

Prenatal programming of sexual partner preference: The ram model

Roselli, C. E. & Stormshak, F., 2009, In : Journal of Neuroendocrinology. 21, 4, p. 359-364 6 p.

Research output: Contribution to journalArticle

Embryonic and Fetal Development
Sexual Partners
Sheep
Aromatase
Anterior Hypothalamus
13 Citations
Pregnanolone
Enzyme activity
Oxidoreductases
Ethanol
Seizures
9 Citations

The amphibian (rana esculenta) brain progesterone receptor: Relationship to plasma steroids and vitellogenic cycle during the gonadal recovery phase

Guerriero, G., Roselli, C. E. & Ciarcia, G., Apr 2009, Annals of the New York Academy of Sciences. Vol. 1163, p. 407-409 3 p. (Annals of the New York Academy of Sciences; vol. 1163)

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Rana esculenta
Amphibians
Progesterone Receptors
Brain
Steroids
22 Citations

The neurobiology of sexual partner preferences in rams

Roselli, C. E. & Stormshak, F., May 2009, In : Hormones and Behavior. 55, 5, p. 611-620 10 p.

Research output: Contribution to journalArticle

Neurobiology
Sexual Partners
Sex Differentiation
Testosterone
Estradiol
13 Citations

The volume of the ovine sexually dimorphic nucleus of the preoptic area is independent of adult testosterone concentrations

Roselli, C. E., Estill, C. T., Stadelman, H. L. & Stormshak, F., Jan 16 2009, In : Brain Research. 1249, p. 113-117 5 p.

Research output: Contribution to journalArticle

Preoptic Area
Testosterone
Sheep
Aromatase
Messenger RNA
2008
7 Citations

Changes in LH secretion in response to an estradiol challenge in male- and female-oriented rams and in ewes

Stormshak, F., Estill, C. T., Resko, J. A. & Roselli, C. E., May 2008, In : Reproduction. 135, 5, p. 733-738 6 p.

Research output: Contribution to journalArticle

Estradiol
Sexual Behavior
Breeding
Therapeutics
7 Citations

Estrogen, Testosterone, and Sequential Movement in Men

Siegel, J. A., Young, L. A., Neiss, M. B., Samuels, M. H., Roselli, C. E. & Janowsky, J. S., Oct 2008, In : Behavioral Neuroscience. 122, 5, p. 955-962 8 p.

Research output: Contribution to journalArticle

Testosterone
Estrogens
Gonadal Steroid Hormones
Hormones
Corpus Striatum
15 Citations

Prolactin expression in the sheep brain

Roselli, C. E., Bocklandt, S., Stadelman, H. L., Wadsworth, T., Vilain, E. & Stormshak, F., May 2008, In : Neuroendocrinology. 87, 4, p. 206-215 10 p.

Research output: Contribution to journalArticle

Prolactin
Sheep
Brain
Messenger RNA
Preoptic Area
2007
86 Citations

Brain aromatase: Roles in reproduction and neuroprotection

Roselli, C. F. Aug 2007 In : Journal of Steroid Biochemistry and Molecular Biology. 106, 1-5, p. 143-150 8 p.

Research output: Contribution to journalArticle

Aromatase
Reproduction
Brain
Aromatization
Testosterone
Sex Differentiation
Steroid Receptors
Sheep
Hormones
Brain
16 Citations

Effects of dietary saw palmetto on the prostate of transgenic adenocarcinoma of the mouse prostate model (TRAMP)

Wadsworth, T. L., Worstell, T. R., Greenberg, N. M. & Roselli, C. E., May 1 2007, In : Prostate. 67, 6, p. 661-673 13 p.

Research output: Contribution to journalArticle

Transgenic Mice
Prostate
Adenocarcinoma
Dihydrotestosterone
Oxidoreductases
1 Citations

Foreword

González-Mariscal, G. & Roselli, C. E. Jun 2007 In : Hormones and Behavior. 52, 1, p. 1 1 p.

Research output: Contribution to journalArticle

23 Citations

Lack of vasoactive intestinal peptide reduces testosterone levels and reproductive aging in mouse testis

Lacombe, A., Lelievre, V., Roselli, C. E., Muller, J. M., Waschek, J. A. & Vilain, E., Jul 2007, In : Journal of Endocrinology. 194, 1, p. 153-160 8 p.

Research output: Contribution to journalArticle

Vasoactive Intestinal Peptide
Testosterone
Testis
3-Hydroxysteroid Dehydrogenases
Seminiferous Tubules
23 Citations

Neuronal activity of aromatase enzyme in non-copulating male rats

Portillo, W., Castillo, C. G., Retana-Márquez, S., Roselli, C. E. & Paredes, R. G., Feb 2007, In : Journal of Neuroendocrinology. 19, 2, p. 139-141 3 p.

Research output: Contribution to journalArticle

Aromatase
Enzymes
Testosterone
Preoptic Area
Sexual Behavior

Rôle du peptide vasoactif intestinal (VIP) dans la stéroïdogenèse et le vieillissement testiculaire

Lacombe, A., Lelievre, V., Roselli, C. E., Muller, J. M., Waschek, J. A. & Vilain, E., Jun 2007, In : Andrologie. 17, 2, p. 123-128 6 p.

Research output: Contribution to journalArticle

Vasoactive Intestinal Peptide
Testis
Testosterone
Seminiferous Tubules
Follicle Stimulating Hormone
90 Citations

Role of P450 aromatase in sex-specific astrocytic cell death

Liu, M., Hurn, P. D., Roselli, C. E. & Alkayed, N. J., Jan 5 2007, In : Journal of Cerebral Blood Flow and Metabolism. 27, 1, p. 135-141 7 p.

Research output: Contribution to journalArticle

Aromatase
Cell Death
Astrocytes
Oxygen
Glucose
40 Citations

The ovine sexually dimorphic nucleus of the medial preoptic area is organized prenatally by testosterone

Roselli, C. E., Stadelman, H., Reeve, R., Bishop, C. V. & Stormshak, F., Sep 2007, In : Endocrinology. 148, 9, p. 4450-4457 8 p.

Research output: Contribution to journalArticle

Preoptic Area
Testosterone
Sheep
Testosterone Propionate
Aromatase
32 Citations

The ram as a model for behavioral neuroendocrinology

Perkins, A. & Roselli, C. E., Jun 2007, In : Hormones and Behavior. 52, 1, p. 70-77 8 p.

Research output: Contribution to journalArticle

Neuroendocrinology
Sexual Behavior
Testosterone
Sexual Partners
Reproductive Behavior
2006
29 Citations

Delayed testicular aging in pituitary adenylate cyclase-activating peptide (PACAP) null mice

Lacombe, A., Lelievre, V., Roselli, C. E., Salameh, W., Lue, Y. H., Lawson, G., Muller, J. M., Waschek, J. A. & Vilain, E., Mar 7 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 10, p. 3793-3798 6 p.

Research output: Contribution to journalArticle

Adenylyl Cyclases
Peptides
Germ Cells
Reactive Oxygen Species
Animal Structures
16 Citations

Expression of steroid hormone receptors in the fetal sheep brain during the critical period for sexual differentiation

Roselli, C. E., Resko, J. A. & Stormshak, F., Sep 19 2006, In : Brain Research. 1110, 1, p. 76-80 5 p.

Research output: Contribution to journalArticle

Sex Differentiation
Steroid Receptors
Preoptic Area
Sheep
Androgen Receptors
28 Citations

The effect of aromatase inhibition on the sexual differentiation of the sheep brain

Roselli, C. E., Schrunk, J. M., Stadelman, H. L., Resko, J. A. & Stormshak, F., Jun 2006, In : Endocrine. 29, 3, p. 501-511 11 p.

Research output: Contribution to journalArticle

Androstatrienes
Sex Differentiation
Aromatase
Sheep
Brain

Un neuropeptide à l'origine du vieillissement testiculaire?

Lacombe, A., Lelièvre, V., Roselli, C. E., Salameh, W., Lue, Y. H., Lawson, G., Muller, J. M., Waschek, J. A. & Vilain, E., Oct 2006, In : Médecine sciences : M/S. 22, 10, p. 809-811 3 p.

Research output: Contribution to journalArticle

2004
11 Citations

Distribution of aromatase activity in brain and peripheral tissues of male sheep: Effect of nutrition

Sharma, T. P., Blache, D., Roselli, C. E. & Martin, G. B., 2004, In : Reproduction, Fertility and Development. 16, 7, p. 709-715 7 p.

Research output: Contribution to journalArticle

Aromatase
Sheep
nutrition
brain
estradiol
21 Citations
JNK Mitogen-Activated Protein Kinases
Heat-Shock Proteins
Insulin-Like Growth Factor I
Protein Kinases
Prostate