Carol Beadling

Research Assistant Professor

  • 2939 Citations
  • 27 h-Index
1987 …2017

Research output per year

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Research Output

  • 2939 Citations
  • 27 h-Index
  • 52 Article
  • 3 Review article
  • 2 Letter
  • 1 Comment/debate
1987

Toad splenocytes bind human IL-2 and anti-human IL-2 receptor antibody specifically

Langeberg, L., Ruben, L. N., Malley, A., Shiigi, S. & Beadling, C., Jan 1987, In : Immunology Letters. 14, 2, p. 103-110 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
1988
Open Access
11 Scopus citations

The substitution of carrier priming of helper function in the Common American Newt, Notophthalmus viridescens by lectins and human lymphokines

Ruben, L. N., Beadling, C., Langeberg, L., Shiigi, S. & Selden, N., Jan 1 1988, In : Thymus. 11, 2, p. 77-87 11 p.

Research output: Contribution to journalArticle

3 Scopus citations
1990

A monoclonal mouse anti-human IL-2 receptor antibody (anti-Tac) will recognize molecules on the surface of Xenopus laevis immunocytes which specifically bind rIL-2 and are only slightly larger than the human Tac protein

Ruben, L. N., Langeberg, L., Malley, A., Clothier, R. H., Beadling, C., Lee, R. & Shiigi, S., May 1990, In : Immunology Letters. 24, 2, p. 117-125 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
1993

Isolation of interleukin 2-induced immediate-early genes

Beadling, C., Johnson, K. W. & Smith, K. A., Apr 1 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 7, p. 2719-2723 5 p.

Research output: Contribution to journalArticle

Open Access
130 Scopus citations

Tactics for the isolation of interleukin-2-induced immediate-early genes

Beadling, C. & Smith, K. A., Oct 1993, In : Seminars in Immunology. 5, 5, p. 365-373 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
1994

Activation of JAK kinases and STAT proteins by interleukin-2 and interferon α, but not the T cell antigen receptor, in human T lymphocytes

Beadling, C., Guschin, D., Witthuhn, B. A., Ziemiecki, A., Ihle, J. N., Kerr, I. M. & Cantrell, D. A., Dec 1 1994, In : EMBO Journal. 13, 23, p. 5605-5615 11 p.

Research output: Contribution to journalArticle

185 Scopus citations

In search of cytokine-response genes

Beadling, C. & Smith, K. A., May 1994, In : Immunology Today. 15, 5, p. 197-199 3 p.

Research output: Contribution to journalArticle

In search of cytokine-response genes

Beadling, C. & Smith, K. A., May 1994, In : Trends in Immunology. 15, 5, p. 197-199 3 p.

Research output: Contribution to journalArticle

6 Scopus citations
1995

Interleukin‐7 can induce the activation of Jak 1, Jak 3 and STAT 5 proteins in murine T cells

Foxwell, B. M. J., Beadling, C., Guschin, D., Kerr, I. & Cantrell, D., Nov 1995, In : European Journal of Immunology. 25, 11, p. 3041-3046 6 p.

Research output: Contribution to journalArticle

97 Scopus citations
1996

Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor α gene

Lécine, P., Algarté, M., Rameil, P., Beadling, C., Bucher, P., Nabholz, M. & Imbert, J., 1996, In : Molecular and cellular biology. 16, 12, p. 6829-6840 12 p.

Research output: Contribution to journalArticle

Open Access
95 Scopus citations

Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway

Beadling, C., Ng, J., Babbage, J. W. & Cantrell, D. A., Apr 15 1996, In : EMBO Journal. 15, 8, p. 1902-1913 12 p.

Research output: Contribution to journalArticle

158 Scopus citations
1997

Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene.

Lécine, P., Algarté, M., Rameil, P., Beadling, C., Bucher, P., Nabholz, M. & Imbert, J., Apr 1997, In : Molecular and Cellular Biology. 17, 4, p. 2351 1 p.

Research output: Contribution to journalArticle

Erratum: Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor α gene (Molecular and Cellular Biology 16:12 (6831))

Lecine, P., Algarte, M., Rameil, P., Beadling, C., Bucher, P., Nabholz, M. & Imbert, J., 1997, In : Molecular and cellular biology. 17, 4, 1 p.

Research output: Contribution to journalComment/debate

Open Access
3 Scopus citations
1999

Cytokine response gene 6 induces p21 and regulates both cell growth and arrest

Fan, W., Richter, G., Cereseto, A., Beadling, C. & Smith, K. A., Nov 11 1999, In : Oncogene. 18, 47, p. 6573-6582 10 p.

Research output: Contribution to journalArticle

Open Access
50 Scopus citations

Regulators of G protein signaling exhibit distinct patterns of gene expression and target G protein specificity in human lymphocytes

Beadling, C., Druey, K. M., Richter, G., Kehrl, J. H. & Smith, K. A., Mar 1 1999, In : Journal of Immunology. 162, 5, p. 2677-2682 6 p.

Research output: Contribution to journalArticle

86 Scopus citations
2001

Cytokine response gene 8 (CR8) regulates the cell cycle G1-S phase transition and promotes cellular survival

Beadling, C., Cereseto, A., Fan, W., Naramura, M. & Smith, K. A., Mar 29 2001, In : Oncogene. 20, 14, p. 1771-1783 13 p.

Research output: Contribution to journalArticle

6 Scopus citations
2002

DNA array analysis of interleukin-2-regulated immediate/early genes

Beadling, C. & Smith, K. A., Nov 18 2002, In : Medical Immunology. 1, 2.

Research output: Contribution to journalArticle

63 Scopus citations
2004

How do viral infections predispose patients to bacterial infections?

Beadling, C. & Slifka, M. K., Jun 1 2004, In : Current Opinion in Infectious Diseases. 17, 3, p. 185-191 7 p.

Research output: Contribution to journalReview article

99 Scopus citations
2005

Differential regulation of virus-specific T-cell effector functions following activation by peptide or innate cytokines

Beadling, C. & Slifka, M. K., Feb 1 2005, In : Blood. 105, 3, p. 1179-1186 8 p.

Research output: Contribution to journalArticle

39 Scopus citations
2006

Quantifying viable virus-specific T cells without a priori knowledge of fine epitope specificity

Beadling, C. & Slifka, M. K., Oct 1 2006, In : Nature medicine. 12, 10, p. 1208-1212 5 p.

Research output: Contribution to journalArticle

27 Scopus citations
69 Scopus citations
2008

KIT gene mutations and copy number in melanoma subtypes

Beadling, C., Jacobson-Dunlop, E., Hodi, F. S., Le, C., Warrick, A., Patterson, J., Town, A., Harlow, A., Cruz, F., Azar, S., Rubin, B. P., Muller, S., West, R., Heinrich, M. C. & Corless, C. L., Nov 1 2008, In : Clinical Cancer Research. 14, 21, p. 6821-6828 8 p.

Research output: Contribution to journalArticle

418 Scopus citations
2010

High prevalence of PIK3CA/AKT pathway mutations in papillary neoplasms of the breast

Troxell, M. L., Levine, J., Beadling, C., Warrick, A., Dunlap, J., Presnell, A., Patterson, J., Shukla, A., Olson, N. R., Heinrich, M. C. & Corless, C. L., Jan 1 2010, In : Modern Pathology. 23, 1, p. 27-37 11 p.

Research output: Contribution to journalArticle

73 Scopus citations

MET receptor sequence variants R970C and T992I lack transforming capacity

Tyner, J. W., Fletcher, L. B., Wang, E. Q., Yang, W. F., Rutenberg-Schoenberg, M. L., Beadling, C., Mori, M., Heinrich, M. C., Deininger, M. W., Druker, B. J. & Loriaux, M. M., Aug 1 2010, In : Cancer Research. 70, 15, p. 6233-6237 5 p.

Research output: Contribution to journalArticle

55 Scopus citations
2011

Immunohistochemical and molecular markers in breast phyllodes tumors

Korcheva, V. B., Levine, J., Beadling, C., Warrick, A., Countryman, G., Olson, N. R., Heinrich, M. C., Corless, C. L. & Troxell, M. L., Mar 1 2011, In : Applied Immunohistochemistry and Molecular Morphology. 19, 2, p. 119-125 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Multiplex Mutation screening by mass spectrometry: Evaluation of 820 cases from a personalized cancer medicine registry

Beadling, C., Heinrich, M. C., Warrick, A., Forbes, E. M., Nelson, D., Justusson, E., Levine, J., Neff, T. L., Patterson, J., Presnell, A., McKinley, A., Winter, L. J., Dewey, C., Harlow, A., Barney, O., Druker, B. J., Schuff, K. G. & Corless, C. L., Sep 2011, In : Journal of Molecular Diagnostics. 13, 5, p. 504-513 10 p.

Research output: Contribution to journalArticle

69 Scopus citations
2012

Biphasic papillary and lobular breast carcinoma with PIK3CA and IDH1 mutations

Ang, D., Vansandt, A. M., Beadling, C., Warrick, A., West, R. B., Corless, C. L. & Troxell, M. L., Dec 1 2012, In : Diagnostic Molecular Pathology. 21, 4, p. 221-224 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

BRAF and KRAS mutations in sporadic glomus tumors

Chakrapani, A., Warrick, A., Nelson, D., Beadling, C. & Corless, C. L., Jul 1 2012, In : American Journal of Dermatopathology. 34, 5, p. 533-535 3 p.

Research output: Contribution to journalArticle

18 Scopus citations

Mucinous breast carcinomas lack PIK3CA and AKT1 mutations

Kehr, E. L., Jorns, J. M., Ang, D., Warrick, A., Neff, T., Degnin, M., Lewis, R., Beadling, C., Corless, C. L. & Troxell, M. L., Dec 1 2012, In : Human Pathology. 43, 12, p. 2207-2212 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Multiplex high-throughput gene mutation analysis in acute myeloid leukemia

Dunlap, J., Beadling, C., Warrick, A., Neff, T., Fleming, W. H., Loriaux, M., Heinrich, M. C., Kovacsovics, T., Kelemen, K., Leeborg, N., Gatter, K., Braziel, R. M., Press, R., Corless, C. L. & Fan, G., Dec 1 2012, In : Human Pathology. 43, 12, p. 2167-2176 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Multiplex mutation screening by mass spectrometry in gastrointestinal stromal tumours

Kang, G., Lee, J., Jang, K. T., Beadling, C., Corless, C. L., Heinrich, M. C., Park, J. O., Kang, W. K., Park, C. K. & Kim, K. M., Aug 2012, In : Pathology. 44, 5, p. 460-464 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Newly described activating JAK3 mutations in T-cell acute lymphoblastic leukemia

Bains, T., Heinrich, M. C., Loriaux, M. M., Beadling, C., Nelson, D., Warrick, A., Neff, T. L., Tyner, J. W., Dunlap, J., Corless, C. L. & Fan, G., Sep 1 2012, In : Leukemia. 26, 9, p. 2144-2146 3 p.

Research output: Contribution to journalLetter

44 Scopus citations

Phosphatidylinositol-3-kinase pathway mutations are common in breast columnar cell lesions

Troxell, M. L., Brunner, A. L., Neff, T., Warrick, A., Beadling, C., Montgomery, K., Zhu, S., Corless, C. L. & West, R. B., Jul 1 2012, In : Modern Pathology. 25, 7, p. 930-937 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

RAS mutations in therapy-related acute myeloid leukemia after successful treatment of acute promyelocytic leukemia

Kelemen, K., Kovacsovics, T., Braziel, R., Corless, C., Beadling, C. & Fan, G., May 1 2012, In : Leukemia and Lymphoma. 53, 5, p. 999-1002 4 p.

Research output: Contribution to journalLetter

1 Scopus citations
2013

BRAF mutant gastrointestinal stromal tumor: First report of regression with BRAF inhibitor dabrafenib (GSK2118436) and whole exomic sequencing for analysis of acquired resistance

Falchook, G. S., Trent, J. C., Heinrich, M. C., Beadling, C., Patterson, J., Bastida, C. C., Blackman, S. C. & Kurzrock, R., 2013, In : Oncotarget. 4, 2, p. 310-315 6 p.

Research output: Contribution to journalArticle

87 Scopus citations

Combining highly multiplexed PCR with semiconductor-based sequencing for rapid cancer genotyping

Beadling, C., Neff, T. L., Heinrich, M. C., Rhodes, K., Thornton, M., Leamon, J., Andersen, M. & Corless, C. L., Mar 1 2013, In : Journal of Molecular Diagnostics. 15, 2, p. 171-176 6 p.

Research output: Contribution to journalArticle

97 Scopus citations

Cytokine-Mediated Programmed Proliferation of Virus-Specific CD8+ Memory T Cells

Raué, H. P., Beadling, C., Haun, J. & Slifka, M. K., Jan 24 2013, In : Immunity. 38, 1, p. 131-139 9 p.

Research output: Contribution to journalArticle

54 Scopus citations

Frequent PIK3CA mutations in radial scars

Wolters, K. L., Ang, D., Warrick, A., Beadling, C., Corless, C. L. & Troxell, M. L., Dec 1 2013, In : Diagnostic Molecular Pathology. 22, 4, p. 210-214 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Imatinib for melanomas harboring mutationally activated or amplified kit arising on mucosal, acral, and chronically sun-damaged skin

Hodi, F. S., Corless, C. L., Giobbie-Hurder, A., Fletcher, J. A., Zhu, M., Marino-Enriquez, A., Friedlander, P., Gonzalez, R., Weber, J. S., Gajewski, T. F., O'Day, S. J., Kim, K. B., Lawrence, D., Flaherty, K. T., Luke, J. J., Collichio, F. A., Ernstoff, M. S., Heinrich, M. C., Beadling, C., Zukotynski, K. A. & 4 others, Yap, J. T., Van Den Abbeele, A. D., Demetri, G. D. & Fisher, D. E., Sep 10 2013, In : Journal of Clinical Oncology. 31, 26, p. 3182-3190 9 p.

Research output: Contribution to journalArticle

292 Scopus citations

MDM2 amplification and PI3KCA mutation in a case of sclerosing rhabdomyosarcoma

Kikuchi, K., Wettach, G. R., Ryan, C. W., Hung, A., Hooper, J. E., Beadling, C., Warrick, A., Corless, C. L., Olson, S. B., Keller, C. & Mansoor, A., 2013, In : Sarcoma. 2013, 520858.

Research output: Contribution to journalArticle

8 Scopus citations

Novel method for PIK3CA mutation analysis: Locked nucleic acid-PCR sequencing

Ang, D., O'Gara, R., Schilling, A., Beadling, C., Warrick, A., Troxell, M. L. & Corless, C. L., May 1 2013, In : Journal of Molecular Diagnostics. 15, 3, p. 312-318 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

PIK3CA-AKT pathway mutations in micropapillary breast carcinoma

Flatley, E., Ang, D., Warrick, A., Beadling, C., Corless, C. L. & Troxell, M. L., Jul 1 2013, In : Human Pathology. 44, 7, p. 1320-1327 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
2014

Combination therapy for KIT-mutant mast cells: Targeting constitutive NFAT and KIT activity

Macleod, A. C., Klug, L. R., Patterson, J., Griffith, D. J., Beadling, C., Town, A. & Heinrich, M. C., Dec 1 2014, In : Molecular cancer therapeutics. 13, 12, p. 2840-2851 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Frequent phosphatidylinositol-3-kinase mutations in proliferative breast lesions

C Ang, D., Warrick, A. L., Shilling, A., Beadling, C., Corless, C. L. & Troxell, M. L., May 2014, In : Modern Pathology. 27, 5, p. 740-750 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Genetic profiling to determine risk of relapse-free survival in high-risk localized prostate cancer

Barnett, C. M., Heinrich, M. C., Lim, J., Nelson, D., Beadling, C., Warrick, A., Neff, T., Higano, C. S., Garzotto, M., Qian, D., Corless, C. L., Thomas, G. V. & Beer, T. M., Jan 1 2014, In : Clinical Cancer Research. 20, 5, p. 1306-1312 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Mutation profiling in gallbladder cancer in Indian population

Kumari, N., Corless, C. L., Warrick, A., Beadling, C., Nelson, D., Neff, T., Krishnani, N. & Kapoor, V. K., Jan 1 2014, In : Indian Journal of Pathology and Microbiology. 57, 1, p. 9-12 4 p.

Research output: Contribution to journalArticle

19 Scopus citations

Oncogenic mutations in melanomas and benign melanocytic nevi of the female genital tract

Tseng, D., Kim, J., Warrick, A., Nelson, D., Pukay, M., Beadling, C., Heinrich, M., Selim, M. A., Corless, C. L. & Nelson, K., Aug 2014, In : Journal of the American Academy of Dermatology. 71, 2, p. 229-236 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
2015

Assessing copy number alterations in targeted, amplicon-based next-generation sequencing data

Grasso, C., Butler, T., Rhodes, K., Quist, M., Neff, T. L., Moore, S., Tomlins, S. A., Reinig, E., Beadling, C., Andersen, M. & Corless, C. L., Jan 1 2015, In : Journal of Molecular Diagnostics. 17, 1, p. 53-63 11 p.

Research output: Contribution to journalArticle

74 Scopus citations

KRAS and KIT gatekeeper mutations confer polyclonal primary imatinib resistance in GI stromal tumors: Relevance of concomitant phosphatidylinositol 3-kinase/AKT dysregulation

Serrano, C., Wang, Y., Mariño-Enríquez, A., Lee, J. C., Ravegnini, G., Morgan, J. A., Bertagnolli, M. M., Beadling, C., Demetri, G. D., Corless, C. L., Heinrich, M. C. & Fletcher, J. A., Aug 1 2015, In : Journal of Clinical Oncology. 33, 22, p. e93-e96

Research output: Contribution to journalArticle

25 Scopus citations