Beverly Emerson

Staff Scientist

  • 4666 Citations
  • 31 h-Index
1984 …2017

Research output per year

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Research Output

  • 4666 Citations
  • 31 h-Index
  • 42 Article
  • 4 Review article
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Article
2017

The β-NAD+ salvage pathway and PKC-mediated signaling influence localized PARP-1 activity and CTCF Poly(ADP) ribosylation

Henderson, D. J. P., Miranda, J. J. L. & Emerson, B., Jan 1 2017, In : Oncotarget. 8, 39, p. 64698-64713 16 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2015

Genome-wide targeting of the epigenetic regulatory protein ctcf to gene promoters by the transcription factor TFII-I

Peñ A-Hernández, R., Marques, M., Hilmi, K., Zhao, T., Saad, A., Alaoui-Jamali, M. A., Rincon, S. V. D., Ashworth, T., Roy, A. L., Emerson, B. M. & Witcher, M., Feb 17 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 7, p. E677-E686

Research output: Contribution to journalArticle

Open Access
28 Scopus citations
2014

P50-associated COX-2 Extragenic RNA (pacer) activates human COX-2 gene expression by occluding repressive NF-κB p50 complexes

Krawczyk, M. & Emerson, B. M., Apr 29 2014, In : eLife. 2014, 3, e01776.

Research output: Contribution to journalArticle

Open Access
142 Scopus citations

Single-cell analyses of transcriptional heterogeneity during drug tolerance transition in cancer cells by RNA sequencing

Lee, M. C. W., Lopez-Diaz, F. J., Khan, S. Y., Tariq, M. A., Dayn, Y., Vaske, C. J., Radenbaugh, A. J., Kim, H. J., Emerson, B. M. & Pourm, N., Nov 4 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 44, p. E4726-E4735

Research output: Contribution to journalArticle

Open Access
78 Scopus citations
2013

Coordinate Transcriptional and Translational Repression of p53 by TGF-β1 Impairs the Stress Response

López-Díaz, F. J., Gascard, P., Balakrishnan, S. K., Zhao, J., delRincon, S. V., Spruck, C., Tlsty, T. D. & Emerson, B. M., May 23 2013, In : Molecular Cell. 50, 4, p. 552-564 13 p.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations
2012

Functional and molecular characterization of the role of CTCF in human embryonic stem cell biology

Balakrishnan, S. K., Witcher, M., Berggren, T. W. & Emerson, B. M., Aug 3 2012, In : PloS one. 7, 8, e42424.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations
2011

Identification of kinase inhibitors that target transcription initiation by RNA polymerase II

Morachis, J. M., Huang, R. & Emerson, B. M., Jan 1 2011, In : Oncotarget. 2, 1-2, p. 18-28 11 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2010

Regulation of the p53 transcriptional response by structurally diverse core promoters

Morachis, J. M., Murawsky, C. M. & Emerson, B. M., Jan 15 2010, In : Genes and Development. 24, 2, p. 135-147 13 p.

Research output: Contribution to journalArticle

Open Access
64 Scopus citations
2009

Epigenetic Silencing of the p16INK4a Tumor Suppressor Is Associated with Loss of CTCF Binding and a Chromatin Boundary

Witcher, M. & Emerson, B. M., May 15 2009, In : Molecular Cell. 34, 3, p. 271-284 14 p.

Research output: Contribution to journalArticle

Open Access
141 Scopus citations
2008

BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells

Kaeser, M. D., Aslanian, A., Dong, M. Q., Yates, J. R. & Emerson, B. M., Nov 21 2008, In : Journal of Biological Chemistry. 283, 47, p. 32254-32263 10 p.

Research output: Contribution to journalArticle

Open Access
134 Scopus citations
2006

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program

Gomes, N. P., Bjerke, G., Llorente, B., Szostek, S. A., Emerson, B. M. & Espinosa, J. M., Mar 1 2006, In : Genes and Development. 20, 5, p. 601-612 12 p.

Research output: Contribution to journalArticle

Open Access
199 Scopus citations
2005

Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

Zhang, X., Odom, D. T., Koo, S. H., Conkright, M. D., Canettieri, G., Best, J., Chen, H., Jenner, R., Herbolsheimer, E., Jacobsen, E., Kadam, S., Ecker, J. R., Emerson, B., Hogenesch, J. B., Unterman, T., Young, R. A. & Montminy, M., Mar 22 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 12, p. 4459-4464 6 p.

Research output: Contribution to journalArticle

Open Access
668 Scopus citations

The HS2 enhancer of the β-globin locus control region initiates synthesis of non-coding, polyadenylated RNAs independent of a cis-linked globin promoter

Ling, J., Baibakov, B., Pi, W., Emerson, B. M. & Tuan, D., Jul 29 2005, In : Journal of molecular biology. 350, 5, p. 883-896 14 p.

Research output: Contribution to journalArticle

44 Scopus citations
2004

A methylation-mediator complex in hormone signaling

Xu, W., Cho, H., Kadam, S., Banayo, E. M., Anderson, S., Yates, J. R., Emerson, B. M. & Evans, R. M., Jan 15 2004, In : Genes and Development. 18, 2, p. 144-156 13 p.

Research output: Contribution to journalArticle

Open Access
109 Scopus citations

Identification of small-molecule antagonist that inhibit an activator:coactivator interaction

Best, J. L., Amezcua, C. A., Mayr, B., Flechner, L., Murawsky, C. M., Emerson, B., Zor, T., Gardner, K. H. & Montminy, M., Dec 21 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 51, p. 17622-17627 6 p.

Research output: Contribution to journalArticle

Open Access
140 Scopus citations
2003

p53 functions through stress- and promoter-specific recruitment of transcription initiation components before and after DNA damage

Espinosa, J. M., Verdun, R. E. & Emerson, B. M., Oct 2003, In : Molecular Cell. 12, 4, p. 1015-1027 13 p.

Research output: Contribution to journalArticle

Open Access
203 Scopus citations

Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes

Kadam, S. & Emerson, B. M., Feb 1 2003, In : Molecular Cell. 11, 2, p. 377-389 13 p.

Research output: Contribution to journalArticle

Open Access
266 Scopus citations
2001

A transcriptional switch mediated by cofactor methylation

Xu, W., Chen, H., Du, K., Asahara, H., Tini, M., Emerson, B. M., Montminy, M. & Evans, R. H., Dec 21 2001, In : Science. 294, 5551, p. 2507-2511 5 p.

Research output: Contribution to journalArticle

316 Scopus citations
Open Access
146 Scopus citations

Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment

Espinosa, J. M. & Emerson, B. M., Jan 1 2001, In : Molecular Cell. 8, 1, p. 57-69 13 p.

Research output: Contribution to journalArticle

Open Access
348 Scopus citations
2000

Functional selectivity of recombinant mammalian SWI/SNF subunits

Kadam, S., McAlpine, G. S., Phelan, M. L., Kingston, R. E., Jones, K. A. & Emerson, B. M., Oct 1 2000, In : Genes and Development. 14, 19, p. 2441-2451 11 p.

Research output: Contribution to journalArticle

Open Access
178 Scopus citations

HMG I/Y regulates long-range enhancer-dependent transcription on DNA and chromatin by changes in DNA topology

Bagga, R., Michalowski, S., Sabnis, R., Griffith, J. D. & Emerson, B. M., Jul 1 2000, In : Nucleic acids research. 28, 13, p. 2541-2550 10 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations
1999
1 Scopus citations
1998

A SWI/SNF-related chromatin remodeling complex, E-RC1, is required for tissue-specific transcriptional regulation by EKLF in vitro

Armstrong, J. A., Bieker, J. J. & Emerson, B. M., Oct 2 1998, In : Cell. 95, 1, p. 93-104 12 p.

Research output: Contribution to journalArticle

Open Access
260 Scopus citations

Role of chromatin structure and distal enhancers in tissue-specific transcriptional regulation in vitro

Bagga, R., Armstrong, J. A. & Emerson, B. M., Jan 1 1998, In : Cold Spring Harbor symposia on quantitative biology. 63, p. 569-576 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Transcription of chromatin: These are complex times

Armstrong, J. A. & Emerson, B. M., Apr 1998, In : Current Opinion in Genetics and Development. 8, 2, p. 165-172 8 p.

Research output: Contribution to journalArticle

76 Scopus citations
1997
Open Access
36 Scopus citations

Distal enhancer regulation by promoter derepression in topologically constrained DNA in vitro

Barton, M. C., Madani, N. & Emerson, B. M., Jul 8 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 14, p. 7257-7262 6 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations
1996

NF-E2 disrupts chromatin structure at human β-globin locus control region hypersensitive site 2 in vitro

Armstrong, J. A. & Emerson, B. M., Sep 30 1996, In : Molecular and Cellular Biology. 16, 10, p. 5634-5644 11 p.

Research output: Contribution to journalArticle

91 Scopus citations

Regulated gene expression in reconstituted chromatin and synthetic nuclei

Barton, M. C. & Emerson, B. M., Jan 1 1996, In : Methods in Enzymology. 274, p. 299-312 14 p.

Research output: Contribution to journalArticle

9 Scopus citations
1994

Regulated expression of the β-globin gene locus in synthetic nuclei

Barton, M. C. & Emerson, B. M., Oct 15 1994, In : Genes and Development. 8, 20, p. 2453-2465 13 p.

Research output: Contribution to journalArticle

Open Access
50 Scopus citations
1993

The erythroid protein cGATA-1 functions with a stage-specific factor to activate transcription of chromatin-assembled β-globin genes

Barton, M. C., Madani, N. & Emerson, B. M., Jan 1 1993, In : Genes and Development. 7, 9, p. 1796-1809 14 p.

Research output: Contribution to journalArticle

Open Access
38 Scopus citations
1992

The erythroid-specific protein cGATA-1 mediates distal enhancer activity through a specialized β-globin TATA box

Fong, T. C. & Emerson, B. M., Jan 1 1992, In : Genes and Development. 6, 4, p. 521-532 12 p.

Research output: Contribution to journalArticle

Open Access
67 Scopus citations
1990

Site-directed, recombination-mediated mutagenesis of a complex gene locus

Barton, M. C., Hoekstra, M. F. & Emerson, B. M., Dec 1 1990, In : Nucleic acids research. 18, 24, p. 7349-7355 7 p.

Research output: Contribution to journalArticle

21 Scopus citations
1989

Erythroid-specific activation and derepression of the chick β-globin promoter in vitro

Emerson, B. M., Nickol, J. M. & Fong, T. C., Jun 30 1989, In : Cell. 57, 7, p. 1189-1200 12 p.

Research output: Contribution to journalArticle

45 Scopus citations
1987

Analysis of the tissue-specific enhancer at the 3' end of the chicken adult beta-globin gene.

Emerson, B. M., Nickol, J. M., Jackson, P. D. & Felsenfeld, G., Jul 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 14, p. 4786-4790 5 p.

Research output: Contribution to journalArticle

Open Access
54 Scopus citations
1986

Chromatin structure near transcriptionally active genes.

Felsenfeld, G., Emerson, B. M., Jackson, P. D., Lewis, C. D. & Nickol, J. M., Jan 1 1986, In : Progress in clinical and biological research. 218, p. 63-74 12 p.

Research output: Contribution to journalArticle

3 Scopus citations
1985

Interaction of specific nuclear factors with the nuclease-hypersensitive region of the chicken adult β-globin gene: Nature of the binding domain

Emerson, B. M., Lewis, C. D. & Felsenfeld, G., May 1985, In : Cell. 41, 1, p. 21-30 10 p.

Research output: Contribution to journalArticle

134 Scopus citations

Specific protein-DNA interactions associated with active and inactive forms of the chicken adult β-globin gene

Emerson, B. M., Jackson, P. D. & Felsenfeld, G., Jan 1 1985, In : Federation Proceedings. 44, 5, p. No. 7936

Research output: Contribution to journalArticle

1984

DNA sequences and transcription factor interactions of active and inactive forms of mammalian 5 S RNA genes

Emerson, B. M. & Roeder, R. G., Jan 1 1984, In : Journal of Biological Chemistry. 259, 12, p. 7926-7935 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Isolation and genomic arrangement of active and inactive forms of mammalian 5 S RNA genes

Emerson, B. M. & Roeder, R. G., Jan 1 1984, In : Journal of Biological Chemistry. 259, 12, p. 7916-7925 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
Open Access
142 Scopus citations