Benjamin Burwitz

Assistant Professor

  • 1991 Citations
  • 20 h-Index
20072020

Research output per year

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Research Output

  • 1991 Citations
  • 20 h-Index
  • 39 Article
  • 4 Comment/debate
  • 2 Review article
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Article
2020

Spatial and biochemical interactions between bone marrow adipose tissue and hematopoietic stem and progenitor cells in rhesus macaques

Robino, J. J., Pamir, N., Rosario, S., Crawford, L. B., Burwitz, B. J., Roberts, C. T., Kurre, P. & Varlamov, O., Apr 2020, In : Bone. 133, 115248.

Research output: Contribution to journalArticle

1 Scopus citations
2018

The Role of MHC-E in T Cell immunity is conserved among humans, rhesus macaques, and cynomolgus macaques

Wu, H. L., Wiseman, R. W., Hughes, C. M., Webb, G. M., Abdulhaqq, S. A., Bimber, B. N., Hammond, K. B., Reed, J. S., Gao, L., Burwitz, B. J., Greene, J. M., Ferrer, F., Legasse, A. W., Axthelm, M. K., Park, B. S., Brackenridge, S., Maness, N. J., McMichael, A. J., Picker, L. J., O'Connor, D. H. & 2 others, Hansen, S. G. & Sacha, J. B., Jan 1 2018, In : Journal of Immunology. 200, 1, p. 49-60 12 p.

Research output: Contribution to journalArticle

12 Scopus citations
2017

Allogeneic stem cell transplantation in fully MHC-matched Mauritian cynomolgus macaques recapitulates diverse human clinical outcomes

Burwitz, B., Wu, H. L., Abdulhaqq, S., Shriver-Munsch, C., Swanson, T., Legasse, A. W., Hammond, K. B., Junell, S. L., Reed, J. S., Bimber, B. N., Greene, J. M., Webb, G. M., Northrup, M., Laub, W., Kievit, P., MacAllister, R., Axthelm, M., Ducore, R., Lewis, A., Colgin, L. & 9 others, Hobbs, T., Martin, L. D., Ferguson, B., Thomas, C., Panoskaltsis-Mortari, A., Meyers, G., Stanton, J., Maziarz, R. & Sacha, J., Dec 1 2017, In : Nature Communications. 8, 1, 1418.

Research output: Contribution to journalArticle

4 Scopus citations

Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques /631/326/596/1550 /631/326/596/2555 /631/326/596/2557 article

Burwitz, B. J., Wettengel, J. M., Mück-Häusl, M. A., Ringelhan, M., Ko, C., Festag, M. M., Hammond, K. B., Northrup, M., Bimber, B. N., Jacob, T., Reed, J. S., Norris, R., Park, B., Moller-Tank, S., Esser, K., Greene, J. M., Wu, H. L., Abdulhaqq, S., Webb, G., Sutton, W. F. & 8 others, Klug, A., Swanson, T., Legasse, A. W., Vu, T. Q., Asokan, A., Haigwood, N. L., Protzer, U. & Sacha, J. B., Dec 1 2017, In : Nature communications. 8, 1, 2146.

Research output: Contribution to journalArticle

14 Scopus citations

MR1-restricted mucosal-associated invariant T (MAIT) cells respond to mycobacterial vaccination and infection in nonhuman primates

Greene, J. M., Dash, P., Roy, S., McMurtrey, C., Awad, W., Reed, J. S., Hammond, K. B., Abdulhaqq, S., Wu, H. L., Burwitz, B., Roth, B. F., Morrow, D. W., Ford, J. C., Xu, G., Bae, J. Y., Crank, H., Legasse, A. W., Dang, T. H., Greenaway, H. Y., Kurniawan, M. & 14 others, Gold, M., Harriff, M., Lewinsohn, D., Park, B., Axthelm, M., Stanton, J., Hansen, S., Picker, L., Venturi, V., Hildebrand, W., Thomas, P. G., Lewinsohn, D., Adams, E. J. & Sacha, J., May 1 2017, In : Mucosal Immunology. 10, 3, p. 802-813 12 p.

Research output: Contribution to journalArticle

35 Scopus citations
2016

Achieving potent autologous neutralizing antibody responses against tier 2 HIV-1 viruses by strategic selection of envelope immunogens

Hessell, A. J., Malherbe, D. C., Pissani, F., McBurney, S., Krebs, S. J., Gomes, M., Pandey, S., Sutton, W. F., Burwitz, B. J., Gray, M., Robins, H., Park, B. S., Sacha, J. B., La Branche, C. C., Fuller, D. H., Montefiori, D. C., Stamatatos, L., Sather, D. N. & Haigwood, N. L., Apr 1 2016, In : Journal of Immunology. 196, 7, p. 3064-3078 15 p.

Research output: Contribution to journalArticle

31 Scopus citations

Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

Hansen, S., Wu, H. L., Burwitz, B., Hughes, C. M., Hammond, K. B., Ventura, A. B., Reed, J. S., Gilbride, R. M., Ainslie, E., Morrow, D. W., Ford, J. C., Selseth, A. N., Pathak, R., Malouli, D., Legasse, A. W., Axthelm, M., Nelson, J., Gillespie, G. M., Walters, L. C., Brackenridge, S. & 8 others, Sharpe, H. R., López, C. A., Frueh, K., Korber, B. T., McMichael, A. J., Gnanakaran, S., Sacha, J. & Picker, L., Feb 12 2016, In : Science. 351, 6274, p. 714-720 7 p.

Research output: Contribution to journalArticle

135 Scopus citations

Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques

Burwitz, B., Malouli, D., Bimber, B. N., Reed, J. S., Ventura, A. B., Hancock, M., Uebelhoer, L. S., Bhusari, A., Hammond, K. B., Espinosa Trethewy, R. G., Klug, A., Legasse, A. W., Axthelm, M., Nelson, J., Park, B., Streblow, D., Hansen, S., Picker, L., Frueh, K. & Sacha, J., Nov 1 2016, In : PLoS Pathogens. 12, 11, e1006014.

Research output: Contribution to journalArticle

15 Scopus citations

Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication

Ericsen, A. J., Lauck, M., Mohns, M. S., DiNapoli, S. R., Mutschler, J. P., Greene, J. M., Weinfurter, J. T., Lehrer-Brey, G., Prall, T. M., Gieger, S. M., Buechler, C. R., Crosno, K. A., Peterson, E. J., Reynolds, M. R., Wiseman, R. W., Burwitz, B., Estes, J., Sacha, J., Friedrich, T. C., Brenchley, J. M. & 1 others, O’Connor, D. H., Dec 7 2016, In : PLoS Pathogens. 12, 12, e1006048.

Research output: Contribution to journalArticle

15 Scopus citations

Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus

Sturgill, E. R., Malouli, D., Hansen, S., Burwitz, B., Seo, S., Schneider, C. L., Womack, J. L., Verweij, M., Ventura, A. B., Bhusari, A., Jeffries, K. M., Legasse, A. W., Axthelm, M., Hudson, A. W., Sacha, J., Picker, L. & Frueh, K., Aug 1 2016, In : PLoS Pathogens. 12, 8, e1005868.

Research output: Contribution to journalArticle

16 Scopus citations

TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection

Chew, G. M., Fujita, T., Webb, G. M., Burwitz, B. J., Wu, H. L., Reed, J. S., Hammond, K. B., Clayton, K. L., Ishii, N., Abdel-Mohsen, M., Liegler, T., Mitchell, B. I., Hecht, F. M., Ostrowski, M., Shikuma, C. M., Hansen, S. G., Maurer, M., Korman, A. J., Deeks, S. G., Sacha, J. B. & 1 others, Ndhlovu, L. C., Jan 1 2016, In : PLoS pathogens. 12, 1, e1005349.

Research output: Contribution to journalArticle

98 Scopus citations
2014

Expansion of dysfunctional Tim-3 - Expressing effector memory CD8+ T cells during simian immunodeficiency virus infection in rhesus macaques

Fujita, T., Burwitz, B. J., Chew, G. M., Reed, J. S., Pathak, R., Seger, E., Clayton, K. L., Rini, J. M., Ostrowski, M. A., Ishii, N., Kuroda, M. J., Hansen, S. G., Sacha, J. B. & Ndhlovu, L. C., Dec 1 2014, In : Journal of Immunology. 193, 11, p. 5576-5583 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Technical advance: Liposomal alendronate depletes monocytes and macrophages in the nonhuman primate model of human disease

Burwitz, B. J., Reed, J. S., Hammond, K. B., Ohme, M. A., Planer, S. L., Legasse, A. W., Ericsen, A. J., Richter, Y., Golomb, G. & Sacha, J. B., Sep 2014, In : Journal of Leukocyte Biology. 96, 3, p. 491-501 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Tertiary mutations stabilize CD8+ T lymphocyte escape-associated compensatory mutations following transmission of simian immunodeficiency virus

Burwitz, B. J., Wu, H. L., Reed, J. S., Hammond, K. B., Newman, L. P., Bimber, B. N., Nimiyongskul, F. A., Leon, E. J., Maness, N. J., Friedrich, T. C., Yokoyama, M., Sato, H., Matano, T., O'Connor, D. H. & Sacha, J. B., Mar 2014, In : Journal of virology. 88, 6, p. 3598-3604 7 p.

Research output: Contribution to journalArticle

Vaccination against endogenous retrotransposable element consensus sequences does not protect rhesus macaques from SIVsmE660 infection and replication

Sheppard, N. C., Jones, R. B., Burwitz, B. J., Nimityongskul, F. A., Newman, L. P., Buechler, M. B., Reed, J. S., Piaskowski, S. M., Weisgrau, K. L., Castrovinci, P. A., Wilson, N. A., Ostrowski, M. A., Park, B., Nixon, D. F., Rakasz, E. G. & Sacha, J. B., Mar 20 2014, In : PloS one. 9, 3, e92012.

Research output: Contribution to journalArticle

7 Scopus citations
2013

Adoptive transfer of lymphocytes isolated from simian immunodeficiency virus SIVmac239δnef-vaccinated macaques does not affect acute-phase viral loads but may reduce chronic-phase viral loads in major histocompatibility complex-matched recipients

Greene, J. M., Lhost, J. J., Hines, P. J., Scarlotta, M., Harris, M., Burwitz, B. J., Budde, M. L., Dudley, D. M., Pham, N., Cain, B., Mac Nair, C. E., Weiker, M. K., O'Connor, S. L., Friedrich, T. C. & O'Connor, D. H., Jul 1 2013, In : Journal of virology. 87, 13, p. 7382-7392 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Immune clearance of highly pathogenic SIV infection

Hansen, S. G., Jr, M. P., Ventura, A. B., Hughes, C. M., Gilbride, R. M., Ford, J. C., Oswald, K., Shoemaker, R., Li, Y., Lewis, M. S., Gilliam, A. N., Xu, G., Whizin, N., Burwitz, B. J., Planer, S. L., Turner, J. M., Legasse, A. W., Axthelm, M. K., Nelson, J. A., Früh, K. & 6 others, Sacha, J. B., Estes, J. D., Keele, B. F., Edlefsen, P. T., Lifson, J. D. & Picker, L. J., Jan 1 2013, In : Nature. 502, 7469, p. 100-104 5 p.

Research output: Contribution to journalArticle

355 Scopus citations

T cells target APOBEC3 proteins in human immunodeficiency virus type 1-infected humans and simian immunodeficiency virus-infected indian rhesus macaques

Champiat, S., Garrison, K. E., Raposo, R. A. S., Burwitz, B. J., Reed, J., Tandon, R., York, V. A., Newman, L. P., Nimityongskul, F. A., Wilson, N. A., Almeida, R. R., Martin, J. N., Deeks, S. G., Rosenberg, M. G., Wiznia, A. A., Spotts, G. E., Pilcher, C. D., Hecht, F. M., Ostrowski, M. A., Sacha, J. B. & 1 others, Nixon, D. F., Jun 1 2013, In : Journal of virology. 87, 11, p. 6073-6080 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
2012

CD8+ and CD4+ cytotoxic T cell escape mutations precede breakthrough SIVmac239 viremia in an elite controller

Burwitz, B. J., Giraldo-Vela, J. P., Reed, J., Newman, L. P., Bean, A. T., Nimityongskul, F. A., Castrovinci, P. A., Maness, N. J., Leon, E. J., Rudersdorf, R. & Sacha, J. B., Nov 6 2012, In : Retrovirology. 9, 91.

Research output: Contribution to journalArticle

18 Scopus citations

Escape from CD8 + T cell responses in Mamu-B*00801 + macaques differentiates progressors from elite controllers

Mudd, P. A., Ericsen, A. J., Burwitz, B. J., Wilson, N. A., O'Connor, D. H., Hughes, A. L. & Watkins, D. I., Apr 1 2012, In : Journal of Immunology. 188, 7, p. 3364-3370 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Ex vivo SIV-specific CD8 T cell responses in heterozygous animals are primarily directed against peptides presented by a single MHC haplotype

Greene, J. M., Chin, E. N., Budde, M. L., Lhost, J. J., Hines, P. J., Burwitz, B. J., Broman, K. W., Nelson, J. E., Friedrich, T. C. & O'Connor, D. H., Aug 22 2012, In : PloS one. 7, 8, e43690.

Research output: Contribution to journalArticle

1 Scopus citations
2011

Differential MHC class I expression in distinct leukocyte subsets

Greene, J. M., Wiseman, R. W., Lank, S. M., Bimber, B. N., Karl, J. A., Burwitz, B. J., Lhost, J. J., Hawkins, O. E., Kunstman, K. J., Broman, K. W., Wolinsky, S. M., Hildebrand, W. H. & O'Connor, D. H., Jul 15 2011, In : BMC Immunology. 12, 39.

Research output: Contribution to journalArticle

22 Scopus citations

GagCM9-specific CD8 + T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo

Vojnov, L., Martins, M. A., Almeida, J. R., Ende, Z., Rakasz, E. G., Reynolds, M. R., Leon, E. J., Weisgrau, K. L., Burwitz, B. J., Folkvord, J. M., de Santana, M. G. V., Neves, P. C. C., Connick, E., Skinner, P. J., Gostick, E., O'Connor, D. H., Wilson, N. A., Bonaldo, M. C., Galler, R., Price, D. A. & 2 others, Douek, D. C. & Watkins, D. I., Aug 26 2011, In : PloS one. 6, 8, e23515.

Research output: Contribution to journalArticle

9 Scopus citations

Pyrosequencing reveals restricted patterns of CD8 + T cell escape-associated compensatory mutations in simian immunodeficiency virus

Burwitz, B. J., Sacha, J. B., Reed, J. S., Newman, L. P., Norante, F. A., Bimber, B. N., Wilson, N. A., Watkins, D. I. & O'Connor, D. H., Dec 1 2011, In : Journal of virology. 85, 24, p. 13088-13096 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Simian Immunodeficiency Virus SIVmac239Δnef vaccination elicits different Tat28-35SL8-specific CD8+ T-cell clonotypes compared to a DNA prime/adenovirus type 5 boost regimen in rhesus macaques

Burwitz, B. J., Ende, Z., Sudolcan, B., Reynolds, M. R., Greene, J. M., Bimber, B. N., Almeida, J. R., Kurniawan, M., Venturi, V., Gostick, E., Wiseman, R. W., Douek, D. C., Price, D. A. & O'Connor, D. H., Apr 1 2011, In : Journal of virology. 85, 7, p. 3683-3689 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

The role of MHC class I allele Mamu-A *07 during SIV mac239 infection

Reed, J. S., Sidney, J., Piaskowski, S. M., Glidden, C. E., León, E. J., Burwitz, B. J., Kolar, H. L., Eernisse, C. M., Furlott, J. R., Maness, N. J., Walsh, A. D., Rudersdorf, R. A., Bardet, W., McMurtrey, C. P., O'Connor, D. H., Hildebrand, W. H., Sette, A., Watkins, D. I. & Wilson, N. A., Dec 1 2011, In : Immunogenetics. 63, 12, p. 789-807 19 p.

Research output: Contribution to journalArticle

15 Scopus citations

Transcriptionally abundant major histocompatibility complex class I alleles are fundamental to nonhuman primate simian immunodeficiency virus-specific CD8+ T cell responses

Budde, M. L., Lhost, J. J., Burwitz, B. J., Becker, E. A., Burns, C. M., O'Connor, S. L., Karl, J. A., Wiseman, R. W., Bimber, B. N., Zhang, G. L., Hildebrand, W., Brusic, V. & O'Connor, D. H., Apr 1 2011, In : Journal of virology. 85, 7, p. 3250-3261 12 p.

Research output: Contribution to journalArticle

35 Scopus citations
2010

Dynamics of haplotype frequency change in a CD8+TL epitope of simian immunodeficiency virus

Hughes, A. L., O'Connor, S., Dudley, D. M., Burwitz, B. J., Bimber, B. N. & O'Connor, D., May 1 2010, In : Infection, Genetics and Evolution. 10, 4, p. 555-560 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Extralymphoid CD8 + T cells resident in tissue from simian immunodeficiency virus SIVmac239△nef-vaccinated macaques suppress SIVmac239 replication ex vivo

Greene, J. M., Lhost, J. J., Burwitz, B. J., Budde, M. L., Macnair, C. E., Weiker, M. K., Gostick, E., Friedrich, T. C., Broman, K. W., Price, D. A., O'Connor, S. L. & O'Connor, D. H., Apr 1 2010, In : Journal of virology. 84, 7, p. 3362-3372 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

MHC heterozygote advantage in simian immunodeficiency virus-infected Mauritian cynomolgus macaques

O'Connor, S. L., Lhost, J. J., Becker, E. A., Detmer, A. M., Johnson, R. C., MacNair, C. E., Wiseman, R. W., Karl, J. A., Greene, J. M., Burwitz, B. J., Bimber, B. N., Lank, S. M., Tuscher, J. J., Mee, E. T., Rose, N. J., Desrosiers, R. C., Hughes, A. L., Friedrich, T. C., Carrington, M. & O'Connor, D. H., Jun 7 2010, In : Science translational medicine. 2, 22, p. 22ra18

Research output: Contribution to journalArticle

60 Scopus citations
2009

Mauritian cynomolgus macaques share two exceptionally common major histocompatibility complex class I alleles that restrict simian immunodeficiency virus-specific CD8+ T cells

Burwitz, B. J., Pendley, C. J., Greene, J. M., Detmer, A. M., Lhost, J. J., Karl, J. A., Piaskowski, S. M., Rudersdorf, R. A., Wallace, L. T., Bimber, B. N., Loffredo, J. T., Cox, D. G., Bardet, W., Hildebrand, W., Wiseman, R. W., O'Connor, S. L. & O'Connor, D. H., Jun 1 2009, In : Journal of virology. 83, 12, p. 6011-6019 9 p.

Research output: Contribution to journalArticle

52 Scopus citations

Ultradeep pyrosequencing detects complex patterns of CD8+ T-lymphocyte escape in simian immunodeficiency virus-infected macaques

Bimber, B. N., Burwitz, B. J., O'Connor, S., Detmer, A., Gostick, E., Lank, S. M., Price, D. A., Hughes, A. & O'Connor, D., Aug 1 2009, In : Journal of virology. 83, 16, p. 8247-8253 7 p.

Research output: Contribution to journalArticle

54 Scopus citations
2008

Allogeneic lymphocytes persist and traffic in feral MHC-matched Mauritian cynomolgus macaques

Greene, J. M., Burwitz, B. J., Blasky, A. J., Mattila, T. L., Hong, J. J., Rakasz, E. G., Wiseman, R. W., Hasenkrug, K. J., Skinner, P. J., O'Connor, S. L. & O'Connor, D. H., Jun 11 2008, In : PloS one. 3, 6, e2384.

Research output: Contribution to journalArticle

21 Scopus citations
2007

CD8+ T cells from SIV elite controller macaques recognize mamu-B*08-bound epitopes and select for widespread viral variation

Loffredo, J. T., Friedrich, T. C., León, E. J., Stephany, J. J., Rodrigues, D. S., Spencer, S. P., Bean, A. T., Beal, D. R., Burwitz, B. J., Rudersdorf, R. A., Wallace, L. T., Piaskowski, S. M., May, G. E., Sidney, J., Gostick, E., Wilson, N. A., Price, D. A., Kallas, E. G., Piontkivska, H., Hughes, A. L. & 2 others, Sette, A. & Watkins, D. I., Nov 14 2007, In : PloS one. 2, 11, e1152.

Research output: Contribution to journalArticle

64 Scopus citations

Composition of the bacterial community in the gut of the pine engraver, Ips pini (Say) (Coleoptera) colonizing red pine

Delalibera, I., Vasanthakumar, A., Burwitz, B. J., Schloss, P. D., Klepzig, K. D., Handelsman, J. & Raffa, K. F., Nov 20 2007, In : Symbiosis. 43, 2, p. 97-104 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression

Sacha, J. B., Chung, W., Rakasz, E. G., Spencer, S. P., Jonas, A. K., Bean, A. T., Lee, W., Burwitz, B. J., Stephany, J. J., Loffredo, J. T., Allison, D. B., Adnan, S., Hoji, A., Wilson, N. A., Friedrich, T. C., Lifson, J. D., Yang, O. O. & Watkins, D. I., Mar 1 2007, In : Journal of Immunology. 178, 5, p. 2746-2754 9 p.

Research output: Contribution to journalArticle

Open Access
207 Scopus citations

Not all cytokine-producing CD8+ T cells suppress simian immunodeficiency virus replication

Chung, W., Lee, W., Loffredo, J. T., Burwitz, B., Friedrich, T. C., Vela, J. P. G., Napoe, G., Rakasz, E. G., Wilson, N. A., Allison, D. B. & Watkins, D. I., Feb 1 2007, In : Journal of virology. 81, 3, p. 1517-1523 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Subdominant CD8+ T-cell responses are involved in durable control of AIDS virus replication

Friedrich, T. C., Valentine, L. E., Yant, L. J., Rakasz, E. G., Piaskowski, S. M., Furlott, J. R., Weisgrau, K. L., Burwitz, B., May, G. E., León, E. J., Soma, T., Napoe, G., Capuano, S. V., Wilson, N. A. & Watkins, D. I., Apr 1 2007, In : Journal of virology. 81, 7, p. 3465-3476 12 p.

Research output: Contribution to journalArticle

164 Scopus citations

The antiviral efficacy of simian immunodeficiency virus-specific CD8 + T cells is unrelated to epitope specificity and is abrogated by viral escape

Loffredo, J. T., Burwitz, B. J., Rakasz, E. G., Spencer, S. P., Stephany, J. J., Vela, J. P. G., Martin, S. R., Reed, J., Piaskowski, S. M., Furlott, J., Weisgrau, K. L., Rodrigues, D. S., Soma, T., Napoé, G., Friedrich, T. C., Wilson, N. A., Kallas, E. G. & Watkins, D. I., Mar 1 2007, In : Journal of virology. 81, 6, p. 2624-2634 11 p.

Research output: Contribution to journalArticle

60 Scopus citations