Projects per year
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- 8 Similar Profiles
Factor XI
Medicine & Life Sciences
Protein C
Medicine & Life Sciences
Thrombosis
Medicine & Life Sciences
Thrombin
Medicine & Life Sciences
Blood Platelets
Medicine & Life Sciences
Factor XII
Medicine & Life Sciences
Primates
Medicine & Life Sciences
Anticoagulants
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 1978 2017
- 4 Finished
Therapeutic factor XI blockade for sepsis
Gruber, A. & Tucker, E.
4/1/15 → 3/31/17
Project: Research project
Factor XI
Sepsis
Disseminated Intravascular Coagulation
Hemorrhage
Therapeutics
Therapeutic factor XI blockade for sepsis
Gruber, A. & Tucker, E.
3/10/10 → 8/31/15
Project: Research project
Factor XI
Sepsis
Monoclonal Antibodies
Factor XIIa
Therapeutics
Thrombin
Fibrinolytic Agents
Enzyme Activators
Protein C
Stroke
REPRODUCTIVE STEROIDS AND EXPERIMENTAL STROKE
Ronnekleiv, O., Hess, D., Casey, D., Duell, P., Machida, C., Dissen, G., Moses, A., Nelson, J., Kohama, S., Wong, S., Urbanski, H., Spindel, E., Stouffer, R., Smith, M. (., Axthelm, M., Neuringer, M., Ojeda, S., Bethea, C., Grove, K., Zelinski, M., Patton, P., Grove, K., Hess, D., Zelinski, M., Orloff, S., Mitalipov, S., Ronnekleiv, O., Lee, D., Coleman, K., Jensen, J., Grove, K., Slayden, O., Picker, L., Sherman, L. (., Zelinski, M., Hennebold, J., Slifka, M., Banine, F., Gruber, A., Wright, J., Ferguson, B., Cornea, A., Grant, K. (., Dissen, G., Lomniczi, A., De Filippis, V., Xu, F., Mitalipov, S., Edelman, A., Haigwood, N., Grigsby, P., Roberts, C., Streblow, D., Kroenke, C. (., Rasanen, J., Lee, D., Lewis, A., Frueh, K., Morrison, S., Reddy, P. (., Helms, C., Cornea, A., Coleman, K., Carbone, L., Lindner, J., McBride, J., Brambrink, A., Sullivan, E., Mallley, A., Beatty, C., Phoenix, C., Funan, H., Fahrenbach, W., Alexander, N., Portman, O., Howard, C., Palotay, J., Egerer, C., Gliessman, P., Critchlow, B. V., Webb, M., Burnham, J., Hill, J., Janina, E., Toyooka, A., McDonald, I., Resko, J., Melner, M., Hermsmeyer, K., Olson, L., McNulty, W., Malinow, R., Kelley, S., Maslar, I. L. A., Joel, I., Hoskins, D., Saneto, R., Ellinwood, W., Towne, D., Critchlow, V., Coffin, R., Koler, R., Laster, L., Malley, A., Kohler, P., Sorensen, T., Lentz, S., Schatten, G., Spence, J. C., Rxnnekleiv, O., Reimann, K., Beer, B., Rajkovic, A., Duffy, D., Sadowsky, D., Shiigi, S., Stouffer Richard, L., Matrisian, L., Toole, J., Meng, L. I., Kohler, P. O., Robertson, J., R Nnekleiv, O., Ridker, P., Shimakawa, T., Karlsson, G., Gravett, M., Hirsch, V., Garg, R., Folsom, A., Gerhard, G., Verhage, H., Murphy, S., Hermsmeyer, R. K., Haluska, G., Hirsch, V., Garg, R., Novy, M. J., Folsom, A., Gerhard, G., Karlsson, G., Gravett, M., Verhage, H., Lewinsohn, D., Lewinsohn, D. M., Letvin, N., Yoshihara, P. H., Rodland, K. D., Sodroski, J., Smith, E., Vitetta, E., Clark, A., K-Y Francis, P., Gravett, M., Cowley, M., Novy, M. J., Frueh, K., Nikolich-Zugich, J., Cowley, D., Adamus, G., [No Value], V. Z., Hanson, S., Lewinsohn, D., Xuemei, W., Adams Waldorf, K., Mayerhofer, A., Sadowsky, D., Dubay, C., Jeffrey, B., Messaoudi, I., Song, P., Matagne, V., Madden, C., Stenzel-Poore, M., Doane, C., Frueh, K., Hoffman, G., Jung, H., McCarron, D., Herzlich, B., Watanabe, M., Nagalla, S., Kronzon, I., Drake, T., Sakata, H., Jennes, L., Gerald, L., Aach, J., Vijayaraghavan, S., Smith, G., Eaton, G., Schwartz, S., Hermsmeyer, R. K., Haluska, G., Novy, M., Spies, H., Kodama, T., Kittner, S., Brenner, R., Simerly, R., Mayerhofer, A., Malinow, M., Wolf, D., Conn, P. M., Cameron, J., Lewinsohn, D., Lewinsohn, D. & Madden, C. (.
5/1/78 → 4/30/14
Project: Research project
Middle Cerebral Artery Infarction
Hormones
Primates
Estrogens
Steroids
Research Output 1984 2019
A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain
Ivanov, I., Matafonov, A., Sun, M. F., Mohammed, B. M., Cheng, Q., Dickeson, S. K., Kundu, S., Verhamme, I. M., Gruber, A., McCrae, K. & Gailani, D., Mar 7 2019, In : Blood. 133, 10, p. 1152-1163 12 p.Research output: Contribution to journal › Article
Hereditary Angioedemas
Factor XII
Prekallikrein
Kallikreins
Chemical activation
Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial
Lorentz, C. U., Verbout, N. G., Wallisch, M., Hagen, M. W., Shatzel, J. J., Olson, S. R., Puy, C., Hinds, M., McCarty, O., Gailani, D., Gruber, A. & Tucker, E., Apr 1 2019, In : Arteriosclerosis, thrombosis, and vascular biology. 39, 4, p. 799-809 11 p.Research output: Contribution to journal › Article
Open Access
Factor XI
Antibodies
Thrombosis
Hemostasis
Primates
Inhibition of contact-mediated activation of factor XI protects baboons against S aureus-induced organ damage and death
Silasi, R., Keshari, R. S., Lupu, C., Van Rensburg, W. J., Chaaban, H., Regmi, G., Shamanaev, A., Shatzel, J. J., Puy, C., Lorentz, C. U., Tucker, E., Gailani, D., Gruber, A., McCarty, O. & Lupu, F., Feb 26 2019, In : Blood advances. 3, 4, p. 658-669 12 p.Research output: Contribution to journal › Article
Open Access
Factor XI
Contact Inhibition
Papio
Sepsis
Disseminated Intravascular Coagulation
Prevention of acute venous stent-induced thrombosis using inhibition of fxii
Nguyen, K. P., Wallisch, M., Johnson, J., Gruber, A. & Hinds, M., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Factor XII
Stents
Venous Thrombosis
Thrombosis
Blood
The role of coagulation and platelets in colon cancer-associated thrombosis
Mitrugno, A., Tassi Yunga, S., Sylman, J. L., Zilberman-Rudenko, J., Shirai, T., Hebert, J. F., Kayton, R., Zhang, Y., Nan, X., Shatzel, J. J., Esener, S., Duvernay, M. T., Hamm, H. E., Gruber, A., Williams, C. D., Takata, Y., Armstrong, R., Morgan, T. & McCarty, O., Feb 1 2019, In : American journal of physiology. Cell physiology. 316, 2, p. C264-C273Research output: Contribution to journal › Article
Colonic Neoplasms
Thrombosis
Blood Platelets
Neoplasms
Cell Communication