Andras Gruber

Professor

  • 3773 Citations
  • 32 h-Index
1978 …2019
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  • 8 Similar Profiles
Factor XI Medicine & Life Sciences
Protein C Medicine & Life Sciences
Thrombosis Medicine & Life Sciences
Thrombin Medicine & Life Sciences
Blood Platelets Medicine & Life Sciences
Factor XII Medicine & Life Sciences
Primates Medicine & Life Sciences
Anticoagulants Medicine & Life Sciences

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Projects 1978 2017

Therapeutic factor XI blockade for sepsis

Gruber, A. & Tucker, E.

National Institutes of Health

4/1/153/31/17

Project: Research project

Factor XI
Sepsis
Disseminated Intravascular Coagulation
Hemorrhage
Therapeutics

Therapeutic factor XI blockade for sepsis

Gruber, A. & Tucker, E.

National Institutes of Health

3/10/108/31/15

Project: Research project

Factor XI
Sepsis
Monoclonal Antibodies
Factor XIIa
Therapeutics

Therapeutic thrombin analogs

Gruber, A. & Tucker, E.

National Institutes of Health

12/1/086/30/17

Project: Research project

Thrombin
Fibrinolytic Agents
Enzyme Activators
Protein C
Stroke

REPRODUCTIVE STEROIDS AND EXPERIMENTAL STROKE

Ronnekleiv, O., Hess, D., Casey, D., Duell, P., Machida, C., Dissen, G., Moses, A., Nelson, J., Kohama, S., Wong, S., Urbanski, H., Spindel, E., Stouffer, R., Smith, M. (., Axthelm, M., Neuringer, M., Ojeda, S., Bethea, C., Grove, K., Zelinski, M., Patton, P., Grove, K., Hess, D., Zelinski, M., Orloff, S., Mitalipov, S., Ronnekleiv, O., Lee, D., Coleman, K., Jensen, J., Grove, K., Slayden, O., Picker, L., Sherman, L. (., Zelinski, M., Hennebold, J., Slifka, M., Banine, F., Gruber, A., Wright, J., Ferguson, B., Cornea, A., Grant, K. (., Dissen, G., Lomniczi, A., De Filippis, V., Xu, F., Mitalipov, S., Edelman, A., Haigwood, N., Grigsby, P., Roberts, C., Streblow, D., Kroenke, C. (., Rasanen, J., Lee, D., Lewis, A., Frueh, K., Morrison, S., Reddy, P. (., Helms, C., Cornea, A., Coleman, K., Carbone, L., Lindner, J., McBride, J., Brambrink, A., Sullivan, E., Mallley, A., Beatty, C., Phoenix, C., Funan, H., Fahrenbach, W., Alexander, N., Portman, O., Howard, C., Palotay, J., Egerer, C., Gliessman, P., Critchlow, B. V., Webb, M., Burnham, J., Hill, J., Janina, E., Toyooka, A., McDonald, I., Resko, J., Melner, M., Hermsmeyer, K., Olson, L., McNulty, W., Malinow, R., Kelley, S., Maslar, I. L. A., Joel, I., Hoskins, D., Saneto, R., Ellinwood, W., Towne, D., Critchlow, V., Coffin, R., Koler, R., Laster, L., Malley, A., Kohler, P., Sorensen, T., Lentz, S., Schatten, G., Spence, J. C., Rxnnekleiv, O., Reimann, K., Beer, B., Rajkovic, A., Duffy, D., Sadowsky, D., Shiigi, S., Stouffer Richard, L., Matrisian, L., Toole, J., Meng, L. I., Kohler, P. O., Robertson, J., R Nnekleiv, O., Ridker, P., Shimakawa, T., Karlsson, G., Gravett, M., Hirsch, V., Garg, R., Folsom, A., Gerhard, G., Verhage, H., Murphy, S., Hermsmeyer, R. K., Haluska, G., Hirsch, V., Garg, R., Novy, M. J., Folsom, A., Gerhard, G., Karlsson, G., Gravett, M., Verhage, H., Lewinsohn, D., Lewinsohn, D. M., Letvin, N., Yoshihara, P. H., Rodland, K. D., Sodroski, J., Smith, E., Vitetta, E., Clark, A., K-Y Francis, P., Gravett, M., Cowley, M., Novy, M. J., Frueh, K., Nikolich-Zugich, J., Cowley, D., Adamus, G., [No Value], V. Z., Hanson, S., Lewinsohn, D., Xuemei, W., Adams Waldorf, K., Mayerhofer, A., Sadowsky, D., Dubay, C., Jeffrey, B., Messaoudi, I., Song, P., Matagne, V., Madden, C., Stenzel-Poore, M., Doane, C., Frueh, K., Hoffman, G., Jung, H., McCarron, D., Herzlich, B., Watanabe, M., Nagalla, S., Kronzon, I., Drake, T., Sakata, H., Jennes, L., Gerald, L., Aach, J., Vijayaraghavan, S., Smith, G., Eaton, G., Schwartz, S., Hermsmeyer, R. K., Haluska, G., Novy, M., Spies, H., Kodama, T., Kittner, S., Brenner, R., Simerly, R., Mayerhofer, A., Malinow, M., Wolf, D., Conn, P. M., Cameron, J., Lewinsohn, D., Lewinsohn, D. & Madden, C. (.

National Institutes of Health

5/1/784/30/14

Project: Research project

Middle Cerebral Artery Infarction
Hormones
Primates
Estrogens
Steroids

Research Output 1984 2019

  • 3773 Citations
  • 32 h-Index
  • 102 Article
  • 2 Chapter
  • 2 Conference contribution

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain

Ivanov, I., Matafonov, A., Sun, M. F., Mohammed, B. M., Cheng, Q., Dickeson, S. K., Kundu, S., Verhamme, I. M., Gruber, A., McCrae, K. & Gailani, D., Mar 7 2019, In : Blood. 133, 10, p. 1152-1163 12 p.

Research output: Contribution to journalArticle

Hereditary Angioedemas
Factor XII
Prekallikrein
Kallikreins
Chemical activation

Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial

Lorentz, C. U., Verbout, N. G., Wallisch, M., Hagen, M. W., Shatzel, J. J., Olson, S. R., Puy, C., Hinds, M., McCarty, O., Gailani, D., Gruber, A. & Tucker, E., Apr 1 2019, In : Arteriosclerosis, thrombosis, and vascular biology. 39, 4, p. 799-809 11 p.

Research output: Contribution to journalArticle

Open Access
Factor XI
Antibodies
Thrombosis
Hemostasis
Primates

Inhibition of contact-mediated activation of factor XI protects baboons against S aureus-induced organ damage and death

Silasi, R., Keshari, R. S., Lupu, C., Van Rensburg, W. J., Chaaban, H., Regmi, G., Shamanaev, A., Shatzel, J. J., Puy, C., Lorentz, C. U., Tucker, E., Gailani, D., Gruber, A., McCarty, O. & Lupu, F., Feb 26 2019, In : Blood advances. 3, 4, p. 658-669 12 p.

Research output: Contribution to journalArticle

Open Access
Factor XI
Contact Inhibition
Papio
Sepsis
Disseminated Intravascular Coagulation

Prevention of acute venous stent-induced thrombosis using inhibition of fxii

Nguyen, K. P., Wallisch, M., Johnson, J., Gruber, A. & Hinds, M., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Factor XII
Stents
Venous Thrombosis
Thrombosis
Blood

The role of coagulation and platelets in colon cancer-associated thrombosis

Mitrugno, A., Tassi Yunga, S., Sylman, J. L., Zilberman-Rudenko, J., Shirai, T., Hebert, J. F., Kayton, R., Zhang, Y., Nan, X., Shatzel, J. J., Esener, S., Duvernay, M. T., Hamm, H. E., Gruber, A., Williams, C. D., Takata, Y., Armstrong, R., Morgan, T. & McCarty, O., Feb 1 2019, In : American journal of physiology. Cell physiology. 316, 2, p. C264-C273

Research output: Contribution to journalArticle

Colonic Neoplasms
Thrombosis
Blood Platelets
Neoplasms
Cell Communication