Amy Farrell

Research Assistant Professor

  • 461 Citations
  • 9 h-Index
20092017
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Fingerprint Dive into the research topics where Amy Farrell is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 11 Similar Profiles
Tumor Suppressor Proteins Medicine & Life Sciences
Protein Phosphatase 2 Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Tumors Chemical Compounds
Proto-Oncogene Proteins c-myc Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Cells Chemical Compounds
Phosphorylation Medicine & Life Sciences

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Research Output 2009 2017

  • 461 Citations
  • 9 h-Index
  • 9 Article
12 Citations (Scopus)

MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance

Farrell, A., Joly, M. M., Allen-Petersen, B. L., Worth, P. J., Lanciault, C., Sauer, D., Link, J., Pelz, C., Heiser, L., Morton, J. P., Muthalagu, N., Hoffman, M. T., Manning, S. L., Pratt, E. D., Kendsersky, N. D., Egbukichi, N., Amery, T. S., Thoma, M. C., Jenny, Z. P., Rhim, A. D. & 5 others, Murphy, D. J., Sansom, O. J., Crawford, H. C., Sheppard, B. & Sears, R., Dec 1 2017, In : Nature Communications. 8, 1, 1728.

Research output: Contribution to journalArticle

Synaptophysin
plastic properties
markers
Plasticity
Tumors
111 Citations (Scopus)

MYC degradation

Farrell, A. S. & Sears, R. C., 2014, In : Cold Spring Harbor perspectives in medicine. 4, 3, a014365.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Ubiquitin
Degradation
Proteins
Oncogene Proteins
83 Citations (Scopus)

Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer

Janghorban, M., Farrell, A., Allen-Petersen, B. L., Pelz, C., Daniel, C. J., Oddo, J., Langer, E. M., Christensen, D. J. & Sears, R., Jun 24 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 25, p. 9157-9162 6 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Breast Neoplasms
Serine
Phosphorylation
Tumor Suppressor Proteins
49 Citations (Scopus)

Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer

Farrell, A., Allen-Petersen, B., Daniel, C. J., Wang, X., Wang, Z., Rodriguez, S., Impey, S., Oddo, J., Vitek, M. P., Lopez, C., Christensen, D. J., Sheppard, B. & Sears, R., 2014, In : Molecular Cancer Research. 12, 6, p. 924-939 16 p.

Research output: Contribution to journalArticle

Tumor Suppressor Proteins
Protein Phosphatase 2
Pancreatic Neoplasms
Therapeutics
Cell Line
53 Citations (Scopus)

Pin1 Regulates the Dynamics of c-Myc DNA Binding To Facilitate Target Gene Regulation and Oncogenesis

Farrell, A., Pelz, C., Wang, X., Daniel, C. J., Wang, Z., Su, Y., Janghorban, M., Zhang, X., Morgan, C., Impey, S. & Sears, R., Aug 2013, In : Molecular and Cellular Biology. 33, 15, p. 2930-2949 20 p.

Research output: Contribution to journalArticle

Carcinogenesis
DNA
Peptidylprolyl Isomerase
Genes
myc Genes