Amy Farrell

Research Assistant Professor

  • 528 Citations
  • 9 h-Index

Research output per year

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Research Output

  • 528 Citations
  • 9 h-Index
  • 9 Article

MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance

Farrell, A. S., Joly, M. M., Allen-Petersen, B. L., Worth, P. J., Lanciault, C., Sauer, D., Link, J., Pelz, C., Heiser, L. M., Morton, J. P., Muthalagu, N., Hoffman, M. T., Manning, S. L., Pratt, E. D., Kendsersky, N. D., Egbukichi, N., Amery, T. S., Thoma, M. C., Jenny, Z. P., Rhim, A. D. & 5 others, Murphy, D. J., Sansom, O. J., Crawford, H. C., Sheppard, B. C. & Sears, R. C., Dec 1 2017, In : Nature communications. 8, 1, 1728.

Research output: Contribution to journalArticle

  • 20 Scopus citations

    MYC degradation

    Farrell, A. S. & Sears, R. C., 2014, In : Cold Spring Harbor Perspectives in Medicine. 4, 3, a014365.

    Research output: Contribution to journalArticle

  • 132 Scopus citations

    Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer

    Janghorban, M., Farrell, A. S., Allen-Petersen, B. L., Pelz, C., Daniel, C. J., Oddo, J., Langer, E. M., Christensen, D. J. & Sears, R. C., Jun 24 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 25, p. 9157-9162 6 p.

    Research output: Contribution to journalArticle

  • 95 Scopus citations

    Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer

    Farrell, A. S., Allen-Petersen, B., Daniel, C. J., Wang, X., Wang, Z., Rodriguez, S., Impey, S., Oddo, J., Vitek, M. P., Lopez, C., Christensen, D. J., Sheppard, B. & Sears, R. C., Jun 2014, In : Molecular Cancer Research. 12, 6, p. 924-939 16 p.

    Research output: Contribution to journalArticle

  • 55 Scopus citations

    Pin1 Regulates the Dynamics of c-Myc DNA Binding To Facilitate Target Gene Regulation and Oncogenesis

    Farrell, A. S., Pelz, C., Wang, X., Daniel, C. J., Wang, Z., Su, Y., Janghorban, M., Zhang, X., Morgan, C., Impey, S. & Sears, R. C., Aug 1 2013, In : Molecular and Cellular Biology. 33, 15, p. 2930-2949 20 p.

    Research output: Contribution to journalArticle

  • 62 Scopus citations