Amanda McCullough

Associate Professor

  • 1363 Citations
  • 19 h-Index
19942018
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Projects 1994 2017

STRUCTURAL STUDIES OF A MAMMALIAN APURINIC ENDONUCLEASE

McCullough, A.

National Institutes of Health

1/10/94 → …

Project: Research projectPostdoctoral Individual National Research Service Award

Cellular Responses to DNA-Protein Crosslinks

Lloyd, R. (., McCullough, A. & McCullough, A.

National Institutes of Health

6/1/043/31/17

Project: Research projectResearch Project

DNA
Proteins
DNA Repair
Mutagenesis
Genes

Research Output 1994 2018

  • 1363 Citations
  • 19 h-Index
  • 39 Article
1 Citations

An RNAi screen in human cell lines reveals conserved DNA damage repair pathways that mitigate formaldehyde sensitivity

Juarez, E., Chambwe, N., Tang, W., Mitchell, A. D., Owen, N., Kumari, A., Monnat, R. J. & McCullough, A., Jan 1 2018, (Accepted/In press) In : DNA Repair.

Research output: Contribution to journalArticle

RNA Interference
DNA Repair
Formaldehyde
DNA Damage
Repair
2 Citations

Modulation of UVB-induced Carcinogenesis by Activation of Alternative DNA Repair Pathways

Sha, Y., Vartanian, V., Owen, N., Mengden Koon, S. J., Calkins, M. J., Thompson, C. S., Mirafzali, Z., Mir, S., Goldsmith, L. E., He, H., Luo, C., Brown, S. M., Doetsch, P. W., Kaempf, A., Lim, J. Y., McCullough, A. K. & Lloyd, R. S., Dec 1 2018, In : Scientific Reports. 8, 1, 705.

Research output: Contribution to journalArticle

Nuclear Localization Signals
DNA Repair
Carcinogenesis
Liposomes
Cell-Penetrating Peptides

Processing of N5-substituted formamidopyrimidine DNA adducts by DNA glycosylases NEIL1 and NEIL3

Minko, I., Christov, P. P., Li, L., Stone, M. P., McCullough, A. & Lloyd, R. S., Jan 1 2018, (Accepted/In press) In : DNA Repair.

Research output: Contribution to journalArticle

DNA Glycosylases
DNA Adducts
Aflatoxin B1
Mechlorethamine
Processing
5 Citations

NEIL1 protects against aflatoxin-induced hepatocellular carcinoma in mice

Vartanian, V., Minko, I. G., Chawanthayatham, S., Egner, P. A., Lin, Y. C., Earley, L. F., Makar, R., Eng, J. R., Camp, M. T., Li, L., Stone, M. P., Lasarev, M. R., Groopman, J. D., Croy, R. G., Essigmann, J. M., McCullough, A. K. & Lloyd, R. S., Apr 18 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 16, p. 4207-4212 6 p.

Research output: Contribution to journalArticle

Aflatoxins
Hepatocellular Carcinoma
DNA Glycosylases
DNA Repair
Xeroderma Pigmentosum
2 Citations

Catalysts of DNA Strand Cleavage at Apurinic/Apyrimidinic Sites

Minko, I. G., Jacobs, A. C., De Leon, A. R., Gruppi, F., Donley, N., Harris, T. M., Rizzo, C. J., McCullough, A. K. & Lloyd, R. S., Jul 1 2016, In : Scientific Reports. 6, 28894.

Research output: Contribution to journalArticle

DNA Glycosylases
Deoxyribose
DNA Cleavage
Single-Stranded DNA Breaks
Purines