Amala Soumyanath

Associate Professor

  • 1862 Citations
  • 22 h-Index
1987 …2018
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Research Output 1987 2018

  • 1862 Citations
  • 22 h-Index
  • 55 Article
  • 1 Book
  • 1 Chapter
  • 1 Conference contribution
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Article
2018
3 Citations (Scopus)
Mucuna
Levodopa
Fluorescence
High Pressure Liquid Chromatography
Parkinson Disease
5 Citations (Scopus)

Centella asiatica attenuates hippocampal mitochondrial dysfunction and improves memory and executive function in β-amyloid overexpressing mice

Gray, N. E., Zweig, J. A., Caruso, M., Zhu, J. Y., Wright, K. M., Quinn, J. & Soumyanath, A., Dec 1 2018, In : Molecular and Cellular Neuroscience. 93, p. 1-9 9 p.

Research output: Contribution to journalArticle

Centella
Executive Function
Amyloid
Antioxidants
Learning
5 Citations (Scopus)

Centella asiatica increases hippocampal synaptic density and improves memory and executive function in aged mice

Gray, N. E., Zweig, J. A., Caruso, M., Martin, M. D., Zhu, J. Y., Quinn, J. & Soumyanath, A., Jul 1 2018, In : Brain and Behavior. 8, 7, e01024.

Research output: Contribution to journalArticle

Centella
Executive Function
Antioxidants
Agave
Reversal Learning
2017
10 Citations (Scopus)

Centella asiatica: phytochemistry and mechanisms of neuroprotection and cognitive enhancement

Gray, N. E., Alcazar Magana, A., Lak, P., Wright, K. M., Quinn, J., Stevens, J. F., Maier, C. S. & Soumyanath, A., Sep 20 2017, (Accepted/In press) In : Phytochemistry Reviews. p. 1-34 34 p.

Research output: Contribution to journalArticle

Centella
Centella asiatica
plant biochemistry
Triterpenes
triterpenoids
8 Citations (Scopus)

Centella asiatica attenuates Aβ-induced neurodegenerative spine loss and dendritic simplification

Gray, N. E., Zweig, J. A., Murchison, C., Caruso, M., Matthews, D. G., Kawamoto, C., Harris, C. J., Quinn, J. & Soumyanath, A., Apr 12 2017, In : Neuroscience Letters. 646, p. 24-29 6 p.

Research output: Contribution to journalArticle

Centella
Dendritic Spines
Neurons
Spine
Alzheimer Disease
7 Citations (Scopus)

Centella asiatica Attenuates Mitochondrial Dysfunction and Oxidative Stress in Aβ-Exposed Hippocampal Neurons

Gray, N. E., Zweig, J. A., Matthews, D. G., Caruso, M., Quinn, J. & Soumyanath, A., 2017, In : Oxidative Medicine and Cellular Longevity. 2017, 7023091.

Research output: Contribution to journalArticle

Centella
Oxidative stress
Neurons
Oxidative Stress
Genotype
2016
23 Citations (Scopus)

Centella asiatica modulates antioxidant and mitochondrial pathways and improves cognitive function in mice

Gray, N. E., Harris, C. J., Quinn, J. & Soumyanath, A., Mar 2 2016, In : Journal of Ethnopharmacology. 180, p. 78-86 9 p.

Research output: Contribution to journalArticle

Centella
Cognition
Antioxidants
Water
Gene Expression
2015
22 Citations (Scopus)

Centella asiatica Attenuates Amyloid-β-Induced Oxidative Stress and Mitochondrial Dysfunction

Gray, N. E., Sampath, H., Zweig, J. A., Quinn, J. & Soumyanath, A., 2015, In : Journal of Alzheimer's Disease. 45, 3, p. 933-946 14 p.

Research output: Contribution to journalArticle

Centella
Amyloid
Oxidative Stress
Antioxidants
Mitochondrial Genes
15 Citations (Scopus)

Curcumin treatment improves motor behavior in α-synuclein transgenic mice

Spinelli, K. J., Osterberg, V. R., Meshul, C. K., Soumyanath, A. & Unni, V., Jun 2 2015, In : PLoS One. 10, 6, e0128510.

Research output: Contribution to journalArticle

Synucleins
Curcumin
curcumin
Transgenic Mice
genetically modified organisms
2014
30 Citations (Scopus)

Caffeoylquinic acids in centella asiatica protect against amyloid-β toxicity

Gray, N. E., Morré, J., Kelley, J., Maier, C. S., Stevens, J. F., Quinn, J. & Soumyanath, A., 2014, In : Journal of Alzheimer's Disease. 40, 2, p. 359-373 15 p.

Research output: Contribution to journalArticle

Centella
Amyloid
Cell Death
Phosphorylation
Cell Line
2012
36 Citations (Scopus)

Centella asiatica extract improves behavioral deficits in a mouse model of Alzheimer's disease: Investigation of a possible mechanism of action

Soumyanath, A., Zhong, Y. P., Henson, E., Wadsworth, T., Bishop, J., Gold, B. G. & Quinn, J., 2012, In : International Journal of Alzheimer's Disease. 381974.

Research output: Contribution to journalArticle

Centella
Alzheimer Disease
Amyloid
Triterpenes
Cholinesterase Inhibitors
2010
44 Citations (Scopus)

Passiflora incarnata L. (Passionflower) extracts elicit GABA currents in hippocampal neurons in vitro, and show anxiogenic and anticonvulsant effects in vivo, varying with extraction method

Elsas, S. M., Rossi, D. J., Raber, J., White, G., Seeley, C. A., Gregory, W. L., Mohr, C., Pfankuch, T. & Soumyanath, A., Oct 2010, In : Phytomedicine. 17, 12, p. 940-949 10 p.

Research output: Contribution to journalArticle

Passiflora
Anticonvulsants
gamma-Aminobutyric Acid
Neurons
Anti-Anxiety Agents
2008
31 Citations (Scopus)

In vivo evaluation of piperine and synthetic analogues as potential treatments for vitiligo using a sparsely pigmented mouse model

Faas, L., Venkatasamy, R., Hider, R. C., Young, A. R. & Soumyanath, A., May 2008, In : British Journal of Dermatology. 158, 5, p. 941-950 10 p.

Research output: Contribution to journalArticle

piperine
Vitiligo
Pigmentation
Melanocytes
Inflammation
2007
33 Citations (Scopus)

Amides from Piper nigrum L. with dissimilar effects on melanocyte proliferation in-vitro

Lin, Z., Liao, Y., Venkatasamy, R., Hider, R. C. & Soumyanath, A., Apr 2007, In : Journal of Pharmacy and Pharmacology. 59, 4, p. 529-536 8 p.

Research output: Contribution to journalArticle

Piper nigrum
piperine
Melanocytes
Amides
Vitiligo
14 Citations (Scopus)

The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD25 expression in humans: A pilot study

Zwickey, H., Brush, J., Iacullo, C. M., Connelly, E., Gregory, W. L., Soumyanath, A. & Buresh, R., Nov 2007, In : Phytotherapy Research. 21, 11, p. 1109-1112 4 p.

Research output: Contribution to journalArticle

Astragalus membranaceus
Echinacea
Glycyrrhiza
T-cells
T-Lymphocytes
2006
47 Citations (Scopus)

The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD69 expression and immune cell activation in humans

Brush, J., Mendenhall, E., Guggenheim, A., Chan, T., Connelly, E., Soumyanath, A., Buresh, R., Barrett, R. & Zwickey, H., Aug 2006, In : Phytotherapy Research. 20, 8, p. 687-695 9 p.

Research output: Contribution to journalArticle

Astragalus membranaceus
Echinacea
Glycyrrhiza
Chemical activation
T-cells
14 Citations (Scopus)

UV irradiation affects melanocyte stimulatory activity and protein binding of piperine

Soumyanath, A., Venkatasamy, R., Joshi, M., Faas, L., Adejuyigbe, B., Drake, A. F., Hider, R. C. & Young, A. R., Nov 2006, In : Photochemistry and Photobiology. 82, 6, p. 1541-1548 8 p.

Research output: Contribution to journalArticle

piperine
Melanocytes
Protein Binding
deoxyribonucleic acid
Irradiation
392 Citations (Scopus)

α-Amylase inhibitory activity of some Malaysian plants used to treat diabetes; with particular reference to Phyllanthus amarus

Ali, H., Houghton, P. J. & Soumyanath, A., Oct 11 2006, In : Journal of Ethnopharmacology. 107, 3, p. 449-455 7 p.

Research output: Contribution to journalArticle

Phyllanthus
Amylases
Oleanolic Acid
Hexanes
Lagerstroemia
2005
83 Citations (Scopus)
Centella
Nerve Regeneration
Neurites
Oral Administration
Axons
2004
61 Citations (Scopus)

Effects of piperine analogues on stimulation of melanocyte proliferation and melanocyte differentiation

Venkatasamy, R., Faas, L., Young, A. R., Soumyanath, A. & Hider, R. C., Apr 15 2004, In : Bioorganic and Medicinal Chemistry. 12, 8, p. 1905-1920 16 p.

Research output: Contribution to journalArticle

piperine
Melanocytes
Melanins
Pentanoic Acids
Rubiaceae
155 Citations (Scopus)

In vitro cytotoxic activity of Thai medicinal plants used traditionally to treat cancer

Itharat, A., Houghton, P. J., Eno-Amooquaye, E., Burke, P. J., Sampson, J. H. & Soumyanath, A., Jan 2004, In : Journal of Ethnopharmacology. 90, 1, p. 33-38 6 p.

Research output: Contribution to journalArticle

Medicinal Plants
Cell Line
Dioscorea
Neoplasms
Dioscoreaceae
2003
32 Citations (Scopus)

Hypoglycemic potentials of methanolic extracts of selected plant foods in alloxanized mice

Ogundipe, O. O., Moody, J. O., Akinyemi, T. O. & Soumyanath, A., 2003, In : Plant Foods for Human Nutrition. 58, 3, p. 1-7 7 p.

Research output: Contribution to journalArticle

Edible Plants
Plant Extracts
food plants
Hypoglycemic Agents
plant extracts
28 Citations (Scopus)

In vitro evaluation of Bacopa monniera on anti-Helicobacter pylori activity and accumulation of prostaglandins

Goel, R. K., Sairam, K., Babu, M. D., Tavares, I. A. & Soumyanath, A., 2003, In : Phytomedicine. 10, 6-7, p. 523-527 5 p.

Research output: Contribution to journalArticle

Bacopa
Helicobacter pylori
Pepsin A
Mucins
Epoprostenol
2001
70 Citations (Scopus)

In vitro keratinocyte antiproliferant effect of Centella asiatica extract and triterpenoid saponins

Sampson, J. H., Soumyanath, A., Karlsen, G., Navsaria, H. & Leigh, I. M. M. O. P., 2001, In : Phytomedicine. 8, 3, p. 230-235 6 p.

Research output: Contribution to journalArticle

Centella
Anthralin
Centella asiatica
triterpenoid saponins
keratinocytes
50 Citations (Scopus)
Plantago
Musa
Pylorus
Antioxidants
Stomach
2000
3 Citations (Scopus)
European Union
Dietary Supplements
North America
Legislation
laws and regulations
2 Citations (Scopus)

Regulatory issues relating to herbal products - Part 2: Safety and toxicity

Forte, J. S. & Soumyanath, A., 2000, In : Journal of Medicinal Food. 3, 1, p. 41-57 17 p.

Research output: Contribution to journalArticle

toxicity
Plant Preparations
Safety
Poisons
European Union
3 Citations (Scopus)

Regulatory issues relating to herbal products - Part 3: Quality and its determination

Forte, J. S. & Soumyanath, A., 2000, In : Journal of Medicinal Food. 3, 1, p. 59-69 11 p.

Research output: Contribution to journalArticle

quality control
Materials Testing
ingredients
testing
European Union
1999
7 Citations (Scopus)

A comparative study of the constituents of Aesculus hippocastanum and Aesculus indica

Srijayanta, S., Soumyanath, A. & Goodwin, B. L., 1999, In : Journal of Medicinal Food. 2, 2, p. 45-50 6 p.

Research output: Contribution to journalArticle

Aesculus indica
Aesculus
Aesculus hippocastanum
hulls
Cotyledon
142 Citations (Scopus)

Antioxidant action and potential antidiabetic properties of an isoflavonoid-containing soyabean phytochemical extract (SPE)

Vedavanam, K., Srijayanta, S., O'Reilly, J., Soumyanath, A. & Wiseman, H., Nov 1999, In : Phytotherapy Research. 13, 7, p. 601-608 8 p.

Research output: Contribution to journalArticle

Phytochemicals
Hypoglycemic Agents
Action Potentials
Antioxidants
Glucose

Development and application of an in-vitro bioassay for plant-derived anti psoriatic agents using SVK-14 keratinocytes

Pires, M., Schlosser, S., Waterfield, C. J., Sampson, J., Che, C. T. & Soumyanath, A., 1999, In : Journal of Pharmacy and Pharmacology. 51, SUPPL., p. 96 1 p.

Research output: Contribution to journalArticle

Keratinocytes
Biological Assay
In Vitro Techniques
23 Citations (Scopus)

Lipoxygenase Inhibitors in the seeds of Aframomum danielli K. Schum (Zingiberaceae)

Odukoya, O. A., Houghton, P. J. & Soumyanath, A., Oct 1999, In : Phytomedicine. 6, 4, p. 251-256 6 p.

Research output: Contribution to journalArticle

Aframomum
Zingiberaceae
Arachidonate 5-Lipoxygenase
Lipoxygenase Inhibitors
benzoquinones
1 Citation (Scopus)

Mangiferin, an antidiabetic compound from Anemarrhena asphodeloides

Srijayanta, S., Jones, P. M., Persaud, S., Hoult, J. R. S. & Soumyanath, A., 1999, In : Journal of Pharmacy and Pharmacology. 51, SUPPL., p. 98 1 p.

Research output: Contribution to journalArticle

Anemarrhena
Hypoglycemic Agents
mangiferin
40 Citations (Scopus)

Stimulation of mouse melanocyte proliferation by Piper nigrum fruit extract and its main alkaloid, piperine

Lin, Z., Hoult, J. R. S., Bennett, D. C. & Soumyanath, A., 1999, In : Planta Medica. 65, 7, p. 600-603 4 p.

Research output: Contribution to journalArticle

piperine
Piper nigrum
fruit extracts
melanocytes
Melanocytes
56 Citations (Scopus)
lissamine rhodamine B
Vitiligo
Drug Evaluation
Melanocytes
Cell Line
1998
1 Citation (Scopus)

A naturally occurring growth promoter for human melanoblasts in culture

Lin, Z., Donatien, P., Soumyanath, A. & Bennett, D. C., Sep 1998, In : Journal of Pharmacy and Pharmacology. 50, SUPPL. 9, p. 218 1 p.

Research output: Contribution to journalArticle

Growth
108 Citations (Scopus)

Antidiabetic and hypocholesterolaemic effects of fenugreek

Al-Habori, M. & Soumyanath, A., Jun 1998, In : Phytotherapy Research. 12, 4, p. 233-242 10 p.

Research output: Contribution to journalArticle

Trigonella
Hypoglycemic Agents
Saponins
Fibers
Insulin

Identification of a phytochemical stimulant for the proliferation of mouse melanocytes in culture

Soumyanath, A., Lin, Z. & Hoult, J. R. S., Sep 1998, In : Journal of Pharmacy and Pharmacology. 50, SUPPL. 9, p. 247 1 p.

Research output: Contribution to journalArticle

Melanocytes
Phytochemicals
4 Citations (Scopus)

In-vitro screening of medicinal plants for potential antidiabetic effects

Srijayanta, S., Jones, P. M., Persaud, S., Lawrence, M. J. & Soumyanath, A., Sep 1998, In : Journal of Pharmacy and Pharmacology. 50, SUPPL. 9, p. 219 1 p.

Research output: Contribution to journalArticle

Medicinal Plants
Hypoglycemic Agents
In Vitro Techniques
1 Citation (Scopus)

Phytochemicals isolated from the anti-hyperglycaemic hexane extract of the unripe fruit of Momordica charuntiu L.

Lau, C., Soumyanath, A., Noel, M., Kergoat, M. & Autier, V., Sep 1998, In : Journal of Pharmacy and Pharmacology. 50, SUPPL. 9, p. 84 1 p.

Research output: Contribution to journalArticle

Momordica
Phytochemicals
Hexanes
Fruit

The Anatomical Features of Powdered Ginkgo biloba L. Leaf as Observed by Light Microscopy

Soumyanath, A. & Croom, E. M., 1998, In : Journal of Medicinal Food. 1, 2, p. 89-95 7 p.

Research output: Contribution to journalArticle

Ginkgo biloba
Microscopy
Calcium Oxalate
Light
Starch
1997
4 Citations (Scopus)

'Herbal' hay fever remedy found to contain conventional drugs

Soumyanath, A. & Jamal, J., Jan 18 1997, In : Pharmaceutical Journal. 258, 6926, p. 105-106 2 p.

Research output: Contribution to journalArticle

Seasonal Allergic Rhinitis
Herbal Medicine
India
Pharmaceutical Preparations

Topic weeks - Delivery of integrated pharmacy teaching to undergraduates

Soumyanath, A., Lansley, A. B. & Greene, R. J., Oct 4 1997, In : Pharmaceutical Journal. 259, 6963, p. 563-565 3 p.

Research output: Contribution to journalArticle

Teaching
1996
12 Citations (Scopus)

Investigation of the effect of Angelica sinensis root extract on the proliferation of melanocytes in culture

Soumyanath, A., Lin, Z. X., Sviderskaya, E. & Kowalska, D., Nov 1996, In : Journal of Ethnopharmacology. 54, 2-3, p. 165-170 6 p.

Research output: Contribution to journalArticle

Angelica sinensis
Melanocytes
Vitiligo
Chinese Traditional Medicine
Thin Layer Chromatography
1995
153 Citations (Scopus)
Tea Tree Oil
Propionibacterium acnes
tea
Staphylococcus aureus
oil
1 Citation (Scopus)

Herbal products: Ginseng

Soumyanath, A. & Houghton, P., 1995, In : Pharmaceutical Journal. 255, 6851, p. 150-152 3 p.

Research output: Contribution to journalArticle

Panax
Names
United Kingdom
1993
Ligustrum
Psoralea
Melanins
Melanoma
Cell Culture Techniques
1 Citation (Scopus)

Effects of sub-lethal doses of cadmium chloride on native and phenobarbitone-induced drug metabolizing enzymes in male rabbits

Anjum, F., Soumyanath, A., Shakoori, A. R. & Gorrod, J. W., 1993, In : Pharmaceutical Science Communications. 4, 1, p. 45-49 5 p.

Research output: Contribution to journalArticle

Cadmium Chloride
Phenobarbital
Rabbits
Enzymes
Pharmaceutical Preparations
1992
9 Citations (Scopus)
Cadmium Chloride
Mixed Function Oxygenases
Metabolic Networks and Pathways
Cadmium
Cytochrome P-450 Enzyme System
1991
46 Citations (Scopus)

Antimicrobial activities of the stembark of Kigelia pinnata

Akunyili, D. N., Houghton, P. J. & Soumyanath, A., 1991, In : Journal of Ethnopharmacology. 35, 2, p. 173-177 5 p.

Research output: Contribution to journalArticle

Iridoids
Bacillus subtilis
Complex Mixtures
Candida albicans
Pseudomonas aeruginosa