Alex Ortega Loayza

Assistant Professor

  • 478 Citations
  • 13 h-Index
20062019
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Research Output 2006 2019

2019
1 Citation (Scopus)

A Comprehensive Review of Local Pharmacologic Therapy for Pyoderma Gangrenosum

Baltazar, D., Haag, C., Gupta, A. S., Marzano, A. M. & Ortega Loayza, A., Jun 1 2019, In : Wounds : a compendium of clinical research and practice. 31, 6, p. 151-157 7 p.

Research output: Contribution to journalArticle

Pyoderma Gangrenosum
Therapeutics
Hematologic Diseases
Proxy
Inflammatory Bowel Diseases
2 Citations (Scopus)

Asociación entre la hidradenitis supurativa y el síndrome metabólico: Revisión sistemática y metaanálisis

Translated title of the contribution: Association Between Hidradenitis Suppurativa and Metabolic Syndrome: A Systematic Review and Meta-analysisRodríguez-Zuñiga, M. J. M., García-Perdomo, H. A. & Ortega Loayza, A., May 1 2019, In : Actas Dermo-Sifiliograficas. 110, 4, p. 279-288 10 p.

Research output: Contribution to journalArticle

Hidradenitis Suppurativa
Meta-Analysis
Odds Ratio
Tertiary Healthcare
Dermatology

Carcinoma Erysipeloides From Metastatic Cutaneous Squamous Cell Carcinoma Initially Mistaken for Intralymphatic Histiocytosis

Heath, M. S., Slaught, C., Ortega Loayza, A. & Mengden, S., Jul 1 2019, In : The American Journal of dermatopathology. 41, 7, p. 522-525 4 p.

Research output: Contribution to journalArticle

Histiocytosis
Squamous Cell Carcinoma
Carcinoma
Skin
Lymphatic Metastasis

Characterisation and diagnosis of ulcers in inpatient dermatology consultation services: A multi-centre study

Haynes, D., Hammer, P., Malachowski, S. J., Kaffenberger, B., Yi, J. S., Vera, N., Calhoun, C., Shinohara, M. M., Seminario-Vidal, L., Trinidad, J. C., Keller, J. J. & Ortega Loayza, A., Jan 1 2019, (Accepted/In press) In : International Wound Journal.

Research output: Contribution to journalArticle

Skin Ulcer
Dermatology
Ulcer
Inpatients
Referral and Consultation
Pyoderma Gangrenosum
Intravenous Immunoglobulins
Ulcer
Therapeutics
PubMed
5 Citations (Scopus)

Clinical Features of Neutrophilic Dermatosis Variants Resembling Necrotizing Fasciitis

Sanchez, I. M., Lowenstein, S., Johnson, K. A., Babik, J., Haag, C., Keller, J. J., Ortega Loayza, A., Cohen, J., McCalmont, T. H., Demer, A. M., Mansh, M. D., Hylwa, S. A., Liu, J. & Shinkai, K., Jan 1 2019, In : JAMA Dermatology. 155, 1, p. 79-84 6 p.

Research output: Contribution to journalArticle

Necrotizing Fasciitis
Skin Diseases
Sweet Syndrome
Pyoderma Gangrenosum
Diagnostic Errors
9 Citations (Scopus)

Development and Validation of a Risk Prediction Model for In-Hospital Mortality among Patients with Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis - ABCD-10

Noe, M. H., Rosenbach, M., Hubbard, R. A., Mostaghimi, A., Cardones, A. R., Chen, J. K., Cotliar, J., Davis, M. D. P., Dominguez, A., Fox, L. P., Hughey, L. C., Kaffenberger, B. H., Kroshinsky, D., Kwong, B. Y., Miller, D. D., Musiek, A., Ortega Loayza, A., Sharon, V. R., Shinkai, K., Summers, E. M. & 6 others, Wanat, K. A., Wetter, D. A., Worswick, S., Margolis, D. J., Gelfand, J. M. & Micheletti, R. G., Apr 1 2019, In : JAMA Dermatology. 155, 4, p. 448-454 7 p.

Research output: Contribution to journalArticle

Stevens-Johnson Syndrome
Bicarbonates
Hospital Mortality
Dialysis
Neoplasms

Do i Have Calciphylaxis?

Keller, J. J. & Ortega Loayza, A., Jan 1 2019, In : JAMA Dermatology.

Research output: Contribution to journalComment/debate

Calciphylaxis
1 Citation (Scopus)

Extracutaneous involvement of pyoderma gangrenosum

Borda, L. J., Wong, L. L., Marzano, A. V. & Ortega Loayza, A., Jan 1 2019, In : Archives of Dermatological Research.

Research output: Contribution to journalReview article

Pyoderma Gangrenosum
Skin Diseases
Polyarteritis Nodosa
Granulomatosis with Polyangiitis
Antiphospholipid Syndrome
3 Citations (Scopus)

Insights Into the Pathogenesis of Sweet's Syndrome

Heath, M. S. & Ortega Loayza, A., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalReview article

Open Access
Sweet Syndrome
Inflammasomes
Skin
Leukocytosis
Skin Diseases
2 Citations (Scopus)

Mechanisms of Inflammation in Neutrophil-Mediated Skin Diseases

Marzano, A. V., Ortega Loayza, A., Heath, M., Morse, D., Genovese, G. & Cugno, M., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalReview article

Open Access
Skin Diseases
Neutrophils
Inflammation
Sweet Syndrome
Inflammasomes

Primary Immunodeficiency, a Possible Cause of Neutrophilic Necrotizing Dermatosis - Reply

Hylwa, S. A., Ortega Loayza, A. & Shinkai, K., Jan 1 2019, In : JAMA Dermatology.

Research output: Contribution to journalLetter

Skin Diseases

Pyoderma gangrenosum: a too often overlooked facultative paraneoplastic disease

Gupta, A. S. & Ortega Loayza, A., Jan 1 2019, In : Annals of hematology.

Research output: Contribution to journalLetter

Pyoderma Gangrenosum

Pyoderma gangrenosum misdiagnosis resulting in amputation: A review

Haag, C. K., Nutan, F., Cyrus, J. W., Satpathy, J., Shinkai, K. & Ortega Loayza, A., Feb 1 2019, In : Journal of Trauma and Acute Care Surgery. 86, 2, p. 307-313 7 p.

Research output: Contribution to journalReview article

Pyoderma Gangrenosum
Diagnostic Errors
Amputation

Ustekinumab use in patients with severe psoriasis co-infected with hepatitis B and/or C

Siegel, S. A. R., Winthrop, K., Ehst, B. B. & Ortega Loayza, A., Jan 1 2019, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalArticle

Hepatitis C
Hepatitis B
Psoriasis
Ustekinumab

White concretions on the hair shaft

Liu, M. & Ortega Loayza, A., Jan 1 2019, In : Cutis. 103, 1, p. E8-E9

Research output: Contribution to journalComment/debate

2018

Antidesmoglein 1 and 3 antibodies in healthy subjects of a population in the Peruvian high amazon

Ramos, W., Díaz, J., Gutierrez, E. L., Lazarte, J. S., Bohnett, M. C., Ronceros, G. & Ortega Loayza, A., Mar 1 2018, In : International Journal of Dermatology. 57, 3, p. 344-348 5 p.

Research output: Contribution to journalArticle

Anti-Idiotypic Antibodies
Healthy Volunteers
Enzyme-Linked Immunosorbent Assay
Antibodies
Immunoglobulin G
4 Citations (Scopus)
Pyoderma Gangrenosum
Lung
1 Citation (Scopus)

Biologic and small-molecule medications in the management of pyoderma gangrenosum

McKenzie, F., Cash, D., Gupta, A., Cummings, L. W. & Ortega Loayza, A., Jan 1 2018, (Accepted/In press) In : Journal of Dermatological Treatment.

Research output: Contribution to journalArticle

Pyoderma Gangrenosum
Therapeutics
Skin
Clinical Pharmacology
Immunosuppressive Agents
7 Citations (Scopus)

Diagnosis and management of peristomal pyoderma gangrenosum: A systematic review

Afifi, L., Sanchez, I. M., Wallace, M. M., Braswell, S. F., Ortega Loayza, A. & Shinkai, K., Jun 1 2018, In : Journal of the American Academy of Dermatology. 78, 6, p. 1195-1204.e1

Research output: Contribution to journalReview article

Pyoderma Gangrenosum
Ostomy
Inflammatory Bowel Diseases
Therapeutics
Guidelines
5 Citations (Scopus)

Diversity in dermatology: Roadmap for improvement

Pritchett, E. N., Pandya, A. G., Ferguson, N. N., Hu, S., Ortega Loayza, A. & Lim, H. W., Aug 1 2018, In : Journal of the American Academy of Dermatology. 79, 2, p. 337-341 5 p.

Research output: Contribution to journalArticle

Dermatology
Medicine
Students
Internship and Residency
Medical Schools
8 Citations (Scopus)

Dysregulation of inflammatory gene expression in lesional and nonlesional skin of patients with pyoderma gangrenosum

Ortega Loayza, A., Nugent, W. H., Lucero, O. M., Washington, S. L., Nunley, J. R. & Walsh, S. W., Jan 1 2018, In : British Journal of Dermatology. 178, 1, p. e35-e36

Research output: Contribution to journalLetter

Open Access
Pyoderma Gangrenosum
Gene Expression
Skin
3 Citations (Scopus)

LPIN2 gene mutation in a patient with overlapping neutrophilic disease (pyoderma gangrenosum and aseptic abscess syndrome)

Marzano, A. V., Ortega Loayza, A., Ceccherini, I. & Cugno, M., Mar 1 2018, In : JAAD Case Reports. 4, 2, p. 120-122 3 p.

Research output: Contribution to journalArticle

Open Access
Pyoderma Gangrenosum
Abscess
Mutation
Genes
1 Citation (Scopus)

Oxidative stress in patients with endemic pemphigus foliaceus and healthy subjects with anti-desmoglein 1 antibodies

Gutierrez, E. L., Seminario-Vidal, L., Ronceros, G., Ramos, W., Tello, M. & Ortega Loayza, A., Mar 1 2018, In : Anais Brasileiros de Dermatologia. 93, 2, p. 212-215 4 p.

Research output: Contribution to journalArticle

Open Access
Desmoglein 1
Healthy Volunteers
Oxidative Stress
Pemphigus
Antibodies
2 Citations (Scopus)

Pyoderma Gangrenosum: What Do We Know Now?

McKenzie, F., Arthur, M. & Ortega Loayza, A., Sep 1 2018, In : Current Dermatology Reports. 7, 3, p. 147-157 11 p.

Research output: Contribution to journalReview article

Pyoderma Gangrenosum
Immunosuppressive Agents
Analgesia
Immune System
Therapeutics
2 Citations (Scopus)

Pyoderma Gangrenosum of the Scalp: A Rare Clinical Variant

Gupta, A. S., Nunley, J. R., Feldman, M. J. & Ortega Loayza, A., Feb 1 2018, In : Wounds : a compendium of clinical research and practice. 30, 2, p. E16-E20

Research output: Contribution to journalArticle

Pyoderma Gangrenosum
Scalp
Immunosuppressive Agents
Inflammatory Bowel Diseases
Craniocerebral Trauma

Reply to: pyoderma gangrenosum: a clinical conundrum

Gupta, A. S., Greiling, T. & Ortega Loayza, A., Oct 1 2018, In : Journal of the European Academy of Dermatology and Venereology. 32, 10, p. e382

Research output: Contribution to journalLetter

Pyoderma Gangrenosum

Reply to: “Wound management strategies in Stevens-Johnson syndrome/toxic epidermal necrolysis: An unmet need”

Castillo, B., Vera, N., Ortega Loayza, A. & Seminario-Vidal, L., Oct 1 2018, In : Journal of the American Academy of Dermatology. 79, 4, p. e89

Research output: Contribution to journalLetter

Stevens-Johnson Syndrome
Wounds and Injuries
14 Citations (Scopus)

Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: A Multicenter Retrospective Study of 377 Adult Patients from the United States

Micheletti, R. G., Chiesa-Fuxench, Z., Noe, M. H., Stephen, S., Aleshin, M., Agarwal, A., Boggs, J., Cardones, A. R., Chen, J. K., Cotliar, J., Davis, M. D. P., Dominguez, A., Fox, L. P., Gordon, S., Hamrick, R., Ho, B., Hughey, L. C., Jones, L. M., Kaffenberger, B. H., Kindley, K. & 22 others, Kroshinsky, D., Kwong, B. Y., Miller, D. D., Mostaghimi, A., Musiek, A., Ortega Loayza, A., Patel, R., Posligua, A., Rani, M., Saluja, S., Sharon, V. R., Shinkai, K., St. John, J., Strickland, N., Sun, N., Wanat, K. A., Wetter, D. A., Worswick, S., Yang, C., Margolis, D. J., Gelfand, J. M. & Rosenbach, M., Nov 1 2018, In : Journal of Investigative Dermatology. 138, 11, p. 2315-2321 7 p.

Research output: Contribution to journalArticle

Stevens-Johnson Syndrome
Poisons
Multicenter Studies
Retrospective Studies
Intravenous Immunoglobulins
1 Citation (Scopus)

Treatment of an ulcerated hemangioma with dehydrated human amnion/chorion membrane allograft

Bacik, L., Dhossche, J., Ortega Loayza, A. & Funk, T., Oct 1 2018, In : JAAD Case Reports. 4, 9, p. 890-892 3 p.

Research output: Contribution to journalArticle

Open Access
Chorion
Amnion
Hemangioma
Allografts
Membranes

Update on calciphylaxis etiopathogenesis, diagnosis, and management

Khanna, U., Dominguez, A., Keller, J., Kroshinsky, D., Ortega Loayza, A., Strowd, L. & Micheletti, R. G., Dec 1 2018, In : Cutis. 102, 6, p. 395-400 6 p.

Research output: Contribution to journalArticle

Calciphylaxis
3 Citations (Scopus)

Wound care for Stevens-Johnson syndrome and toxic epidermal necrolysis

Castillo, B., Vera, N., Ortega Loayza, A. & Seminario-Vidal, L., Oct 1 2018, In : Journal of the American Academy of Dermatology. 79, 4, p. 764-767.e1

Research output: Contribution to journalArticle

Stevens-Johnson Syndrome
Wounds and Injuries
2017
5 Citations (Scopus)

Cutaneous Lupus: A Brief Review of Old and New Medical Therapeutic Options

Nutan, F. & Ortega Loayza, A., Oct 1 2017, In : Journal of Investigative Dermatology Symposium Proceedings. 18, 2, p. S64-S68

Research output: Contribution to journalReview article

Open Access
Cutaneous Lupus Erythematosus
Discoid Lupus Erythematosus
Skin Manifestations
Skin
Systemic Lupus Erythematosus
18 Citations (Scopus)

Drug-induced pyoderma gangrenosum: a model to understand the pathogenesis of pyoderma gangrenosum

Wu, B. C., Patel, E. D. & Ortega Loayza, A., Jul 1 2017, In : British Journal of Dermatology. 177, 1, p. 72-83 12 p.

Research output: Contribution to journalReview article

Pyoderma Gangrenosum
Pharmaceutical Preparations
Keratinocytes
Epigenomics
Neutrophils

Incidental skin malignancies in teledermatology and in-person cohorts in the Veterans Affairs Health System

Keleshian, V., Ortega Loayza, A. & Tarkington, P., Nov 1 2017, In : Journal of the American Academy of Dermatology. 77, 5, p. 965-966 2 p.

Research output: Contribution to journalArticle

Telepathology
Veterans Health
United States Department of Veterans Affairs
Incidental Findings
Skin Neoplasms
4 Citations (Scopus)

Ocular pyoderma gangrenosum: A systematic review

Gupta, A. S. & Ortega Loayza, A., Mar 1 2017, In : Journal of the American Academy of Dermatology. 76, 3, p. 512-518 7 p.

Research output: Contribution to journalArticle

Pyoderma Gangrenosum
Orbit
Corneal Ulcer
Recurrence
Combined Modality Therapy
3 Citations (Scopus)

Somatic symptom disorder in dermatology

Levenson, J. L., Sharma, A. A. & Ortega Loayza, A., May 1 2017, In : Clinics in Dermatology. 35, 3, p. 246-251 6 p.

Research output: Contribution to journalArticle

Dermatology
Psychiatry
Emotions
Body Dysmorphic Disorders
Delusions
2016

Aortic endograft and epithelioid sarcoma: A random association or causality?

Tiwari, N., Krishna, S. & Ortega Loayza, A., Jul 1 2016, In : Journal of Drugs in Dermatology. 15, 7, p. 897-899 3 p.

Research output: Contribution to journalArticle

Hemangiosarcoma
Sarcoma
Causality
Polyethylene Terephthalates
Carcinogens
2 Citations (Scopus)

Calciphylaxis with evidence of hypercoagulability successfully treated with unfractionated heparin: A multidisciplinary approach

Carter, A., Ortega Loayza, A., Barrett, J. & Nunley, J. R., Apr 1 2016, In : Clinical and Experimental Dermatology. 41, 3, p. 275-278 4 p.

Research output: Contribution to journalArticle

Calciphylaxis
Thrombophilia
Heparin
Skin
Hyperparathyroidism
15 Citations (Scopus)

Pyoderma gangrenosum and pregnancy: An example of abnormal inflammation and challenging treatment

Steele, R. B., Nugent, W. H., Braswell, S. F., Frisch, S., Ferrell, J. & Ortega Loayza, A., Jan 1 2016, In : British Journal of Dermatology. 174, 1, p. 77-87 11 p.

Research output: Contribution to journalArticle

Pyoderma Gangrenosum
Inflammation
Pregnancy
Therapeutics
Inflammatory Bowel Diseases

Scattered targetoid papules and mucosal erosions after vaccination

Leib, A. E., Steele, R. B. & Ortega Loayza, A., Oct 1 2016, In : Journal of the American Academy of Dermatology. 75, 4, p. e129-e130

Research output: Contribution to journalArticle

Vaccination
2015
19 Citations (Scopus)

Acute generalized exanthematous pustulosis: Atypical presentations and outcomes

Kostopoulos, T. C., Krishna, S. M., Brinster, N. K. & Ortega Loayza, A., Jan 1 2015, In : Journal of the European Academy of Dermatology and Venereology. 29, 2, p. 209-214 6 p.

Research output: Contribution to journalReview article

Acute Generalized Exanthematous Pustulosis
Drug Hypersensitivity Syndrome
Drug Eruptions
Stevens-Johnson Syndrome
Therapeutics

Dapsone and Autoimmune Bullous Disorders

Werth, V. P. & Ortega Loayza, A., Jan 1 2015, Blistering Diseases: Clinical Features, Pathogenesis, Treatment. Springer Berlin Heidelberg, p. 493-499 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Dapsone
Skin Diseases
Conjunctivitis
Cicatrix
Trichiasis
7 Citations (Scopus)

Molecular characterization and antifungal susceptibility of Cryptococcus neoformans strains collected from a single institution in Lima, Peru

Bejar, V., Tello, M., García, R., Guevara, J. M., Gonzales, S., Vergaray, G., Valencia, E., Abanto, E., Ortega Loayza, A., Hagen, F. & Gutierrez, E. L., Apr 1 2015, In : Revista Iberoamericana de Micologia. 32, 2, p. 88-92 5 p.

Research output: Contribution to journalArticle

Cryptococcus neoformans
Peru
Genotype
Cryptococcus gattii
Tropical Medicine

Pathophysiology of Pyoderma Gangrenosum

Tiwari, N., Kostopoulos, T. C. & Ortega Loayza, A., Jan 1 2015, Advances in Medicine and Biology. Nova Science Publishers, Inc., Vol. 83. p. 1-12 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pyoderma Gangrenosum
Inflammasomes
Skin Diseases
Necrosis
Research Personnel
83 Citations (Scopus)

Pathophysiology of pyoderma gangrenosum (PG): An updated review

Braswell, S. F., Kostopoulos, T. C. & Ortega Loayza, A., Oct 1 2015, In : Journal of the American Academy of Dermatology. 73, 4, p. 691-698 8 p.

Research output: Contribution to journalReview article

Pyoderma Gangrenosum
Skin Manifestations
Thrombophilia
Early Diagnosis
Immune System
2 Citations (Scopus)

Pyoderma gangrenosum after open heart surgery: A rare and challenging postoperative complication

Kostopoulos, T. C., Ortega Loayza, A., Francis, J., Maiberger, M. P., Brinster, N. K., Brinster, D. R., Feldman, M. J. & Nunley, J. R., Jan 1 2015, In : Chirurgia (Turin). 28, 1, p. 37-41 5 p.

Research output: Contribution to journalArticle

Pyoderma Gangrenosum
Thoracic Surgery
Negative-Pressure Wound Therapy
Wounds and Injuries
Immunotherapy

Vulvar edema and weight loss in a pediatric patient

Gupta, A. S., O'Connor, P. W. & Ortega Loayza, A., Jan 1 2015, In : Journal of the American Academy of Dermatology. 73, 6, p. e193-e194

Research output: Contribution to journalArticle

Weight Loss
Edema
Pediatrics
2014
6 Citations (Scopus)

A rapidly progressive and fatal case of atypical acute generalized exanthematous pustulosis

Krishna, S., Ortega Loayza, A., Malakouti, N. & Brinster, N., Jan 1 2014, In : Journal of the American Academy of Dermatology. 71, 3

Research output: Contribution to journalArticle

Open Access
Acute Generalized Exanthematous Pustulosis
Stevens-Johnson Syndrome
Fatal Outcome
Multiple Organ Failure
Combination Drug Therapy
2013
4 Citations (Scopus)

Amlodipine-induced subacute cutaneous lupus

Ortega Loayza, A., McCall, C. O., Cooke, R. H. & Jovin, I. S., Mar 1 2013, In : North American Journal of Medical Sciences. 5, 3, p. 246-247 2 p.

Research output: Contribution to journalLetter

Amlodipine
Skin