Adam Margolin

Professor

  • 11817 Citations
  • 32 h-Index
20042019

Research output per year

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Research Output

2019

Erratum: Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity (Nature (2012) 483 7391 (603-607))

Barretina, J., Caponigro, G., Stransky, N., Venkatesan, K., Margolin, A. A., Kim, S., Wilson, C. J., Lehár, J., Kryukov, G. V., Sonkin, D., Reddy, A., Liu, M., Murray, L., Berger, M. F., Monahan, J. E., Morais, P., Meltzer, J., Korejwa, A., Jané-Valbuena, J., Mapa, F. A. & 41 others, Thibault, J., Bric-Furlong, E., Raman, P., Shipway, A., Engels, I. H., Cheng, J., Yu, G. K., Yu, J., Aspesi, P., de Silva, M., Jagtap, K., Jones, M. D., Wang, L., Hatton, C., Palescandolo, E., Gupta, S., Mahan, S., Sougnez, C., Onofrio, R. C., Liefeld, T., MacConaill, L., Winckler, W., Reich, M., Li, N., Mesirov, J. P., Gabriel, S. B., Getz, G., Ardlie, K., Chan, V., Myer, V. E., Weber, B. L., Porter, J., Warmuth, M., Finan, P., Harris, J. L., Meyerson, M., Golub, T. R., Morrissey, M. P., Sellers, W. R., Schlegel, R. & Garraway, L. A., Jan 1 2019, In : Nature. 565, 7738, p. E5-E6

Research output: Contribution to journalComment/debate

3 Scopus citations
2018

Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection

ICGC-TCGA DREAM Somatic Mutation Calling Challenge Participants, Nov 6 2018, In : Genome biology. 19, 1, 188.

Research output: Contribution to journalArticle

8 Scopus citations

Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy

Medler, T. R., Murugan, D., Horton, W., Kumar, S., Cotechini, T., Forsyth, A. M., Leyshock, P., Leitenberger, J. J., Kulesz-Martin, M., Margolin, A., Werb, Z. & Coussens, L., Oct 8 2018, In : Cancer Cell. 34, 4, p. 561-578.e6

Research output: Contribution to journalArticle

24 Scopus citations

Functional precision medicine identifies novel druggable targets and therapeutic options in head and neck cancer

Xu, C., Nikolova, O., Basom, R. S., Mitchell, R. M., Shaw, R., Moser, R. D., Park, H., Gurley, K. E., Kao, M. C., Green, C. L., Schaub, F. X., Diaz, R. L., Swan, H. A., Jang, I. S., Guinney, J., Gadi, V. K., Margolin, A., Grandori, C., Kemp, C. J. & Méndez, E., Jun 15 2018, In : Clinical Cancer Research. 24, 12, p. 2828-2843 16 p.

Research output: Contribution to journalArticle

6 Scopus citations

Germline contamination and leakage in whole genome somatic single nucleotide variant detection

Sendorek, D. H., Caloian, C., Ellrott, K., Bare, J. C., Yamaguchi, T. N., Ewing, A. D., Houlahan, K. E., Norman, T. C., Margolin, A. A., Stuart, J. M. & Boutros, P. C., Jan 31 2018, In : BMC bioinformatics. 19, 1, 28.

Research output: Contribution to journalArticle

1 Scopus citations

Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism

Davis, R. J., Gonen, M., Margineantu, D. H., Handeli, S., Swanger, J., Hoellerbauer, P., Paddison, P. J., Gu, H., Raftery, D., Grim, J. E., Hockenbery, D. M., Margolin, A. & Clurman, B. E., May 22 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 21, p. 5462-5467 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Population-level distribution and putative immunogenicity of cancer neoepitopes

Wood, M. A., Paralkar, M., Paralkar, M. P., Nguyen, A., Struck, A. J., Ellrott, K., Margolin, A., Nellore, A. & Thompson, R., Apr 13 2018, In : BMC Cancer. 18, 1, 414.

Research output: Contribution to journalArticle

10 Scopus citations

SHIFT: Speedy histopathological-To-immunofluorescent translation of whole slide images using conditional generative adversarial networks

Burlingame, E. A., Margolin, A., Gray, J. & Chang, Y. H., Jan 1 2018, Medical Imaging 2018: Digital Pathology. SPIE, Vol. 10581. 1058105

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Valection: Design optimization for validation and verification studies

Cooper, C. I., Yao, D., Sendorek, D. H., Yamaguchi, T. N., P'ng, C., Houlahan, K. E., Caloian, C., Fraser, M., Ellrott, K., Margolin, A. A., Bristow, R. G., Stuart, J. M. & Boutros, P. C., Sep 25 2018, In : BMC bioinformatics. 19, 1, 339.

Research output: Contribution to journalArticle

2 Scopus citations
2017

A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines

Gonen, M., Weir, B. A., Cowley, G. S., Vazquez, F., Guan, Y., Jaiswal, A., Karasuyama, M., Uzunangelov, V., Wang, T., Tsherniak, A., Howell, S., Marbach, D., Hoff, B., Norman, T. C., Airola, A., Bivol, A., Bunte, K., Carlin, D., Chopra, S., Deran, A. & 25 others, Ellrott, K., Gopalacharyulu, P., Graim, K., Kaski, S., Khan, S. A., Newton, Y., Ng, S., Pahikkala, T., Paull, E., Sokolov, A., Tang, H., Tang, J., Wennerberg, K., Xie, Y., Zhan, X., Zhu, F., Aittokallio, T., Mamitsuka, H., Stuart, J. M., Boehm, J. S., Root, D. E., Xiao, G., Stolovitzky, G., Hahn, W. C. & Margolin, A., 2017, (Accepted/In press) In : Cell Systems.

Research output: Contribution to journalArticle

7 Scopus citations

Breast cancer histopathology image analysis pipeline for tumor purity estimation

Azimi, V., Chang, Y. H., Thibault, G., Smith, J., Tsujikawa, T., Kukull, B., Jensen, B., Corless, C., Margolin, A. & Gray, J., Jun 15 2017, 2017 IEEE 14th International Symposium on Biomedical Imaging, ISBI 2017. IEEE Computer Society, p. 1137-1140 4 p. 7950717

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis

Palpant, N. J., Wang, Y., Hadland, B., Zaunbrecher, R. J., Redd, M., Jones, D., Pabon, L., Jain, R., Epstein, J., Ruzzo, W. L., Zheng, Y., Bernstein, I., Margolin, A. & Murry, C. E., Aug 15 2017, In : Cell Reports. 20, 7, p. 1597-1608 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer

Griffith, M., Spies, N. C., Krysiak, K., McMichael, J. F., Coffman, A. C., Danos, A. M., Ainscough, B. J., Ramirez, C. A., Rieke, D. T., Kujan, L., Barnell, E. K., Wagner, A. H., Skidmore, Z. L., Wollam, A., Liu, C. J., Jones, M. R., Bilski, R. L., Lesurf, R., Feng, Y. Y., Shah, N. M. & 25 others, Bonakdar, M., Trani, L., Matlock, M., Ramu, A., Campbell, K. M., Spies, G. C., Graubert, A. P., Gangavarapu, K., Eldred, J. M., Larson, D. E., Walker, J. R., Good, B. M., Wu, C., Su, A. I., Dienstmann, R., Margolin, A. A., Tamborero, D., Lopez-Bigas, N., Jones, S. J. M., Bose, R., Spencer, D. H., Wartman, L. D., Wilson, R. K., Mardis, E. R. & Griffith, O. L., Jan 31 2017, In : Nature genetics. 49, 2, p. 170-174 5 p.

Research output: Contribution to journalComment/debate

132 Scopus citations

Deep learning based Nucleus Classification in pancreas histological images

Chang, Y. H., Thibault, G., Madin, O., Azimi, V., Meyers, C., Johnson, B., Link, J., Margolin, A. & Gray, J., Sep 13 2017, 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., p. 672-675 4 p. 8036914

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Scopus citations

Integrative analysis on histopathological image for identifying cellular heterogeneity

Chang, Y. H., Thibault, G., Johnson, B., Margolin, A. & Gray, J., 2017, Medical Imaging 2017: Digital Pathology. SPIE, Vol. 10140. 101400T

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Modeling gene-wise dependencies improves the identification of drug response biomarkers in cancer studies

Nikolova, O., Moser, R., Kemp, C., Gonen, M. & Margolin, A., May 1 2017, In : Bioinformatics. 33, 9, p. 1362-1369 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Multiplexed immunohistochemistry image analysis using sparse coding

Chang, Y. H., Tsujikawa, T., Margolin, A., Coussens, L. & Gray, J., Sep 13 2017, 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., p. 4046-4049 4 p. 8037744

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis

Tsujikawa, T., Kumar, S., Borkar, R. N., Azimi, V., Thibault, G., Chang, Y. H., Balter, A., Kawashima, R., Choe, G., Sauer, D., El Rassi, E., Clayburgh, D., Kulesz-Martin, M., Lutz, E. R., Zheng, L., Jaffee, E. M., Leyshock, P., Margolin, A., Mori, M. T., Gray, J. & 2 others, Flint, P. & Coussens, L., Apr 4 2017, In : Cell Reports. 19, 1, p. 203-217 15 p.

Research output: Contribution to journalArticle

113 Scopus citations
2016

Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium

Salomonis, N., Dexheimer, P. J., Omberg, L., Schroll, R., Bush, S., Huo, J., Schriml, L., Ho Sui, S., Keddache, M., Mayhew, C., Shanmukhappa, S. K., Wells, J., Daily, K., Hubler, S., Wang, Y., Zambidis, E., Margolin, A., Hide, W., Hatzopoulos, A. K., Malik, P. & 3 others, Cancelas, J. A., Aronow, B. J. & Lutzko, C., Jul 12 2016, In : Stem Cell Reports. 7, 1, p. 110-125 16 p.

Research output: Contribution to journalArticle

38 Scopus citations

Quantitative analysis of histological tissue image based on cytological profiles and spatial statistics

Chang, Y. H., Thibault, G., Azimi, V., Johnson, B., Jorgens, D., Link, J., Margolin, A. & Gray, J., Oct 13 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Institute of Electrical and Electronics Engineers Inc., Vol. 2016-October. p. 1175-1178 4 p. 7590914

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations
2015

Cancer panomics: Computational methods and nfrastructure for integrative analysis of cancer highthroughput "omics" data

Brunak, S., De La Vega, F. M., Margolin, A., Raphael, B. J., Rätsch, G. & Stuart, J. M., 2015, In : Unknown Journal. p. 8-9 2 p.

Research output: Contribution to journalEditorial

Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection

Ewing, A. D., Houlahan, K. E., Hu, Y., Ellrott, K., Caloian, C., Yamaguchi, T. N., Bare, J. C., P'Ng, C., Waggott, D., Sabelnykova, V. Y., Kellen, M. R., Norman, T. C., Haussler, D., Friend, S. H., Stolovitzky, G., Margolin, A. A., Stuart, J. M. & Boutros, P. C., Jun 30 2015, In : Nature Methods. 12, 7, p. 623-630 8 p.

Research output: Contribution to journalArticle

120 Scopus citations

Stepwise group sparse regression (SGSR): Gene-set-based pharmacogenomic predictive models with stepwise selection of functional priors

Jang, I. S., Dienstmann, R., Margolin, A. & Guinney, J., 2015, 20th Pacific Symposium on Biocomputing, PSB 2015. Stanford University, p. 32-43 12 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

Sperber, H., Mathieu, J., Wang, Y., Ferreccio, A., Hesson, J., Xu, Z., Fischer, K. A., Devi, A., Detraux, D., Gu, H., Battle, S. L., Showalter, M., Valensisi, C., Bielas, J. H., Ericson, N. G., Margaretha, L., Robitaille, A. M., Margineantu, D., Fiehn, O., Hockenbery, D. & 7 others, Blau, C. A., Raftery, D., Margolin, A. A., Hawkins, R. D., Moon, R. T., Ware, C. B. & Ruohola-Baker, H., Nov 27 2015, In : Nature Cell Biology. 17, 12, p. 1523-1535 13 p.

Research output: Contribution to journalArticle

155 Scopus citations

The NIH BD2K center for big data in translational genomics

Paten, B., Diekhans, M., Druker, B., Friend, S., Guinney, J., Gassner, N., Guttman, M., James Kent, W., Mantey, P., Margolin, A., Massie, M., Novak, A. M., Nothaft, F., Pachter, L., Patterson, D., Smuga-Otto, M., Stuart, J. M., Van't Veer, L., Wold, B. & Haussler, D., 2015, In : Journal of the American Medical Informatics Association. 22, 6, p. 1143-1147 5 p.

Research output: Contribution to journalArticle

27 Scopus citations
2014

Assessing the clinical utility of cancer genomic and proteomic data across tumor types

Yuan, Y., Van Allen, E. M., Omberg, L., Wagle, N., Amin-Mansour, A., Sokolov, A., Byers, L. A., Xu, Y., Hess, K. R., Diao, L., Han, L., Huang, X., Lawrence, M. S., Weinstein, J. N., Stuart, J. M., Mills, G. B., Garraway, L. A., Margolin, A. A., Getz, G. & Liang, H., Jul 2014, In : Nature biotechnology. 32, 7, p. 644-652 9 p.

Research output: Contribution to journalArticle

148 Scopus citations

Cancer genomics: Moving from unknown unknown to known unknown

Margolin, A. A., Jan 29 2014, In : Science translational medicine. 6, 221, p. 221ec20

Research output: Contribution to journalEditorial

Functional kinomics identifies candidate therapeutic targets in head and neck cancer

Moser, R., Xu, C., Kao, M., Annis, J., Lerma, L. A., Schaupp, C. M., Gurley, K. E., Jang, I. S., Biktasova, A., Yarbrough, W. G., Margolin, A. A., Grandori, C., Kemp, C. J. & Méndez, E., Aug 15 2014, In : Clinical Cancer Research. 20, 16, p. 4274-4288 15 p.

Research output: Contribution to journalArticle

41 Scopus citations

Global optimization of somatic variant identification in cancer genomes with a global community challenge

Boutros, P. C., Ewing, A. D., Ellrott, K., Norman, T. C., Dang, K. K., Hu, Y., Kellen, M. R., Suver, C., Bare, J. C., Stein, L. D., Spellman, P. T., Stolovitzky, G., Friend, S. H., Margolin, A. A. & Stuart, J. M., Apr 2014, In : Nature genetics. 46, 4, p. 318-319 2 p.

Research output: Contribution to journalLetter

29 Scopus citations

Kernelized Bayesian transfer learning

Gönen, M. & Margolin, A. A., Jan 1 2014, Proceedings of the National Conference on Artificial Intelligence. AI Access Foundation, p. 1831-1839 9 p. (Proceedings of the National Conference on Artificial Intelligence; vol. 3).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

14 Scopus citations

Localized data fusion for kernel k-means clustering with application to cancer biology

Gönen, M. & Margolin, A. A., Jan 1 2014, In : Advances in Neural Information Processing Systems. 2, January, p. 1305-1313 9 p.

Research output: Contribution to journalConference article

50 Scopus citations

Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

The Cancer Genome Atlas Research Network, Aug 14 2014, In : Cell. 158, 4, p. 929-944 16 p.

Research output: Contribution to journalArticle

672 Scopus citations

Simulation studies as designed experiments: The comparison of penalized regression models in the "large p, small n " setting

Neto, E. C., Bare, J. C. & Margolin, A. A., Oct 7 2014, In : PloS one. 9, 10, e107957.

Research output: Contribution to journalArticle

6 Scopus citations

Systematic assessment of analytical methods for drug sensitivity prediction from cancer cell line data

Jang, I. S., Neto, E. C., Guinney, J., Friend, S. H. & Margolin, A. A., Jan 1 2014, In : Pacific Symposium on Biocomputing. p. 63-74 12 p.

Research output: Contribution to journalConference article

66 Scopus citations
20 Scopus citations

To catch a pre-leukemia

Margolin, A. A., Mar 5 2014, In : Science translational medicine. 6, 226, 226ec40.

Research output: Contribution to journalEditorial

Toward better benchmarking: challenge-based methods assessment in cancer genomics

Boutros, P. C., Margolin, A., Stuart, J. M., Califano, A. & Stolovitzky, G., 2014, In : Genome Biology. 15, 9, p. 462 1 p.

Research output: Contribution to journalArticle

27 Scopus citations
2013

ATARiS: Computational quantification of gene suppression phenotypes from multisample RNAi screens

Shao, D. D., Tsherniak, A., Gopal, S., Weir, B. A., Tamayo, P., Stransky, N., Schumacher, S. E., Zack, T. I., Beroukhim, R., Garraway, L. A., Margolin, A. A., Root, D. E., Hahn, W. C. & Mesirov, J. P., Apr 1 2013, In : Genome Research. 23, 4, p. 665-678 14 p.

Research output: Contribution to journalArticle

77 Scopus citations

Cancer therapeutics: Best informed by genes or genomes?

Margolin, A. A., May 8 2013, In : Science translational medicine. 5, 184, 184ec77.

Research output: Contribution to journalComment/debate

1 Scopus citations

Enabling transparent and collaborative computational analysis of 12 tumor types within the Cancer Genome Atlas

Omberg, L., Ellrott, K., Yuan, Y., Kandoth, C., Wong, C., Kellen, M. R., Friend, S. H., Stuart, J., Liang, H. & Margolin, A. A., Oct 1 2013, In : Nature genetics. 45, 10, p. 1121-1126 6 p.

Research output: Contribution to journalReview article

64 Scopus citations

Genomics of T-ALL reveals a weapon of an evasive foe

Margolin, A. A., Mar 27 2013, In : Science translational medicine. 5, 178, 178ec52.

Research output: Contribution to journalComment/debate

hARACNe: Improving the accuracy of regulatory model reverse engineering via higher-order data processing inequality tests

Jang, S., Margolin, A. & Califano, A., Aug 6 2013, In : Interface Focus. 3, 4

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Improving Breast Cancer Survival Analysis through Competition-Based Multidimensional Modeling

Bilal, E., Dutkowski, J., Guinney, J., Jang, I. S., Logsdon, B. A., Pandey, G., Sauerwine, B. A., Shimoni, Y., Moen Vollan, H. K., Mecham, B. H., Rueda, O. M., Tost, J., Curtis, C., Alvarez, M. J., Kristensen, V. N., Aparicio, S., Børresen-Dale, A. L., Caldas, C., Califano, A., Friend, S. H. & 4 others, Ideker, T., Schadt, E. E., Stolovitzky, G. A. & Margolin, A. A., May 1 2013, In : PLoS computational biology. 9, 5, e1003047.

Research output: Contribution to journalArticle

52 Scopus citations

Oncogenic driver mutations: Neither tissue-specific nor independent

Margolin, A. A., Dec 4 2013, In : Science translational medicine. 5, 214, 214ec200.

Research output: Contribution to journalComment/debate

2 Scopus citations

Single-molecule imaging: It takes two to make a RAF signal right

Margolin, A. A., Nov 13 2013, In : Science translational medicine. 5, 211, 211ec187.

Research output: Contribution to journalComment/debate

Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer

Margolin, A. A., Bilal, E., Huang, E., Norman, T. C., Ottestad, L., Mecham, B. H., Sauerwine, B., Kellen, M. R., Mangravite, L. M., Furia, M. D., Vollan, H. K. M., Rueda, O. M., Guinney, J., Deflaux, N. A., Hoff, B., Schildwachter, X., Russnes, H. G., Park, D., Vang, V. O., Pirtle, T. & 10 others, Youseff, L., Citro, C., Curtis, C., Kristensen, V. N., Hellerstein, J., Friend, S. H., Stolovitzky, G., Aparicio, S., Caldas, C. & Børresen-Dale, A. L., Apr 17 2013, In : Science translational medicine. 5, 181, 181re1.

Research output: Contribution to journalArticle

71 Scopus citations

The bionic cancer-resistant extracellular matrix of the naked mole-rat

Margolin, A. A., Jul 31 2013, In : Science translational medicine. 5, 196, 196ec125.

Research output: Contribution to journalComment/debate

1 Scopus citations

The cancer genome atlas pan-cancer analysis project

Weinstein, J. N., Collisson, E. A., Mills, G. B., Shaw, K. R. M., Ozenberger, B. A., Ellrott, K., Sander, C., Stuart, J. M., Chang, K., Creighton, C. J., Davis, C., Donehower, L., Drummond, J., Wheeler, D., Ally, A., Balasundaram, M., Birol, I., Butterfield, Y. S. N., Chu, A., Chuah, E. & 316 others, Chun, H. J. E., Dhalla, N., Guin, R., Hirst, M., Hirst, C., Holt, R. A., Jones, S. J. M., Lee, D., Li, H. I., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Robertson, A. G., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Varhol, R. J., Beroukhim, R., Bhatt, A. S., Brooks, A. N., Cherniack, A. D., Freeman, S. S., Gabriel, S. B., Helman, E., Jung, J., Meyerson, M., Ojesina, A. I., Pedamallu, C. S., Saksena, G., Schumacher, S. E., Tabak, B., Zack, T., Lander, E. S., Bristow, C. A., Hadjipanayis, A., Haseley, P., Kucherlapati, R., Lee, S., Lee, E., Luquette, L. J., Mahadeshwar, H. S., Pantazi, A., Parfenov, M., Park, P. J., Protopopov, A., Ren, X., Santoso, N., Seidman, J., Seth, S., Song, X., Tang, J., Xi, R., Xu, A. W., Yang, L., Zeng, D., Auman, J. T., Balu, S., Buda, E., Fan, C., Hoadley, K. A., Jones, C. D., Meng, S., Mieczkowski, P. A., Parker, J. S., Perou, C. M., Roach, J., Shi, Y., Silva, G. O., Tan, D., Veluvolu, U., Waring, S., Wilkerson, M. D., Wu, J., Zhao, W., Bodenheimer, T., Hayes, D. N., Hoyle, A. P., Jeffreys, S. R., Mose, L. E., Simons, J. V., Soloway, M. G., Baylin, S. B., Berman, B. P., Bootwalla, M. S., Danilova, L., Herman, J. G., Hinoue, T., Laird, P. W., Rhie, S. K., Shen, H., Triche, T., Weisenberger, D. J., Carter, S. L., Cibulskis, K., Chin, L., Zhang, J., Sougnez, C., Wang, M., Getz, G., Dinh, H., Doddapaneni, H. V., Gibbs, R., Gunaratne, P., Han, Y., Kalra, D., Kovar, C., Lewis, L., Morgan, M., Morton, D., Muzny, D., Reid, J., Xi, L., Cho, J., Dicara, D., Frazer, S., Gehlenborg, N., Heiman, D. I., Kim, J., Lawrence, M. S., Lin, P., Liu, Y., Noble, M. S., Stojanov, P., Voet, D., Zhang, H., Zou, L., Stewart, C., Bernard, B., Bressler, R., Eakin, A., Iype, L., Knijnenburg, T., Kramer, R., Kreisberg, R., Leinonen, K., Lin, J., Liu, Y., Miller, M., Reynolds, S. M., Rovira, H., Shmulevich, I., Thorsson, V., Yang, D., Zhang, W., Amin, S., Wu, C. J., Wu, C. C., Akbani, R., Aldape, K., Baggerly, K. A., Broom, B., Casasent, T. D., Cleland, J., Dodda, D., Edgerton, M., Han, L., Herbrich, S. M., Ju, Z., Kim, H., Lerner, S., Li, J., Liang, H., Liu, W., Lorenzi, P. L., Lu, Y., Melott, J., Nguyen, L., Su, X., Verhaak, R., Wang, W., Wong, A., Yang, Y., Yao, J., Yao, R., Yoshihara, K., Yuan, Y., Yung, A. K., Zhang, N., Zheng, S., Ryan, M., Kane, D. W., Aksoy, B. A., Ciriello, G., Dresdner, G., Gao, J., Gross, B., Jacobsen, A., Kahles, A., Ladanyi, M., Lee, W., Lehmann, K. V., Miller, M. L., Ramirez, R., Rätsch, G., Reva, B., Schultz, N., Senbabaoglu, Y., Shen, R., Sinha, R., Sumer, S. O., Sun, Y., Taylor, B. S., Weinhold, N., Fei, S., Spellman, P., Benz, C., Carlin, D., Cline, M., Craft, B., Goldman, M., Haussler, D., Ma, S., Ng, S., Paull, E., Radenbaugh, A., Salama, S., Sokolov, A., Swatloski, T., Uzunangelov, V., Waltman, P., Yau, C., Zhu, J., Hamilton, S. R., Abbott, S., Abbott, R., Dees, N. D., Delehaunty, K., Ding, L., Dooling, D. J., Eldred, J. M., Fronick, C. C., Fulton, R., Fulton, L. L., Kalicki-Veizer, J., Kanchi, K. L., Kandoth, C., Koboldt, D. C., Larson, D. E., Ley, T. J., Lin, L., Lu, C., Magrini, V. J., Mardis, E. R., McLellan, M. D., McMichael, J. F., Miller, C. A., O'Laughlin, M., Pohl, C., Schmidt, H., Smith, S. M., Walker, J., Wallis, J. W., Wendl, M. C., Wilson, R. K., Wylie, T., Zhang, Q., Burton, R., Jensen, M. A., Kahn, A., Pihl, T., Pot, D., Wan, Y., Levine, D. A., Black, A. D., Bowen, J., Frick, J., Gastier-Foster, J. M., Harper, H. A., Helsel, C., Leraas, K. M., Lichtenberg, T. M., McAllister, C., Ramirez, N. C., Sharpe, S., Wise, L., Zmuda, E., Chanock, S. J., Davidsen, T., Demchok, J. A., Eley, G., Felau, I., Sheth, M., Sofia, H., Staudt, L., Tarnuzzer, R., Wang, Z., Yang, L., Zhang, J., Omberg, L., Margolin, A., Raphael, B. J., Vandin, F., Wu, H. T., Leiserson, M. D. M., Benz, S. C., Vaske, C. J., Noushmehr, H., Wolf, D., Veer, L. V. T., Anastassiou, D., Yang, T. H. O., Lopez-Bigas, N., Gonzalez-Perez, A., Tamborero, D., Xia, Z., Li, W., Cho, D. Y., Przytycka, T., Hamilton, M., McGuire, S., Nelander, S., Johansson, P., Jörnsten, R. & Kling, T., Oct 1 2013, In : Nature genetics. 45, 10, p. 1113-1120 8 p.

Research output: Contribution to journalReview article

2137 Scopus citations

The enemy of the enemy of my enemy is a therapeutic target

Margolin, A. A., Jun 19 2013, In : Science translational medicine. 5, 190, 190ec100.

Research output: Contribution to journalEditorial

2012

Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Barretina, J., Caponigro, G., Stransky, N., Venkatesan, K., Margolin, A. A., Kim, S., J.Wilson, C., Lehár, J., Kryukov, G. V., Sonkin, D., Reddy, A., Liu, M., Murray, L., Berger, M. F., Monahan, J. E., Morais, P., Meltzer, J., Korejwa, A., Jané-Valbuena, J., Mapa, F. A. & 41 others, Thibault, J., Bric-Furlong, E., Raman, P., Shipway, A., Engels, I. H., Cheng, J., Yu, G. K., Yu, J., Aspesi, P., de Silva, M., Jagtap, K., Jones, M. D., Wang, L., Hatton, C., Palescandolo, E., Gupta, S., Mahan, S., Sougnez, C., Onofrio, R. C., Liefeld, T., MacConaill, L., Winckler, W., Reich, M., Li, N., Mesirov, J. P., Gabriel, S. B., Getz, G., Ardlie, K., Chan, V., Myer, V. E., Weber, B. L., Porter, J., Warmuth, M., Finan, P., Harris, J. L., Meyerson, M., Golub, T. R., Morrissey, M. P., Sellers, W. R., Schlegel, R. & Garraway, L. A., Nov 28 2012, (Accepted/In press) In : Nature.

Research output: Contribution to journalArticle