Research Output 1987 2019

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2002
135 Citations (Scopus)

μ-opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization

Alvarez, V. A., Arttamangkul, S., Dang, V., Salem, A., Whistler, J. L., Von Zastrow, M., Grandy, D. & Williams, J., Jul 1 2002, In : Journal of Neuroscience. 22, 13, p. 5769-5776 8 p.

Research output: Contribution to journalArticle

Opioid Receptors
Endocytosis
Locus Coeruleus
HEK293 Cells
Potassium
2003
201 Citations (Scopus)

Altered expression of small-conductance Ca2+-activated K+ (SK3) channels modulates arterial tone and blood pressure

Taylor, M. S., Bonev, A. D., Gross, T. P., Eckman, D. M., Brayden, J. E., Bond, C. T., Adelman, J. & Nelson, M. T., Jul 25 2003, In : Circulation Research. 93, 2, p. 124-131 8 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Doxycycline
Endothelium
Arterial Pressure
Apamin
107 Citations (Scopus)

A mouse model of episodic ataxia type-1

Herson, P. S., Virk, M., Rustay, N. R., Bond, C. T., Crabbe, J. J., Adelman, J. & Maylie, J., Apr 1 2003, In : Nature Neuroscience. 6, 4, p. 378-383 6 p.

Research output: Contribution to journalArticle

Inhibitory Postsynaptic Potentials
Carbonic Anhydrase Inhibitors
Voltage-Gated Potassium Channels
Mutation
Acetazolamide
75 Citations (Scopus)

Angiotensin II stimulates hyperplasia but not hypertrophy in immature ovine cardiomyocytes

Sundgren, N. C., Giraud, G., Stork, P., Maylie, J. & Thornburg, K., May 1 2003, In : Journal of Physiology. 548, 3, p. 881-891 11 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Angiotensin II
Hypertrophy
Hyperplasia
Sheep
140 Citations (Scopus)

C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs

Grooteclaes, M., Deveraux, Q., Hildebrand, J., Zhang, Q., Goodman, R. & Frisch, S. M., Apr 15 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 8, p. 4568-4573 6 p.

Research output: Contribution to journalArticle

Gene Expression
Epithelial-Mesenchymal Transition
Apoptosis
Genes
Co-Repressor Proteins
107 Citations (Scopus)

Deacetylase Activity Is Required for cAMP Activation of a Subset of CREB Target Genes

Fass, D. M., Butler, J. E. F. & Goodman, R., Oct 31 2003, In : Journal of Biological Chemistry. 278, 44, p. 43014-43019 6 p.

Research output: Contribution to journalArticle

trichostatin A
Histone Deacetylases
Genes
Chemical activation
Transcription
40 Citations (Scopus)

Determinants contributing to estrogen-regulated expression of SK3

Jacobson, D., Pribnow, D., Herson, P. S., Maylie, J. & Adelman, J., Apr 4 2003, In : Biochemical and Biophysical Research Communications. 303, 2, p. 660-668 9 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Estrogens
Gene expression
Genes
Gene Expression
187 Citations (Scopus)
Co-Repressor Proteins
NAD
Carrier Proteins
Fluorescence Resonance Energy Transfer
Tryptophan
156 Citations (Scopus)

Does Rap1 deserve a bad Rap?

Stork, P., May 1 2003, In : Trends in Biochemical Sciences. 28, 5, p. 267-275 9 p.

Research output: Contribution to journalArticle

Cell Differentiation
Biological Phenomena
Neuronal Plasticity
Monomeric GTP-Binding Proteins
MAP Kinase Signaling System
47 Citations (Scopus)

Dopamine controls the firing pattern of dopamine neurons via a network feedback mechanism

Paladini, C. A., Robinson, S., Morikawa, H., Williams, J. & Palmiter, R. D., Mar 4 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 5, p. 2866-2871 6 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Dopamine
Neuronal Plasticity
Electrophysiology
Patch-Clamp Techniques
10 Citations (Scopus)

Drooling and stuttering, or do synapses whisper?

Jahr, C., Jan 1 2003, In : Trends in Neurosciences. 26, 1, p. 7-9 3 p.

Research output: Contribution to journalArticle

Sialorrhea
Stuttering
Synapses
24 Citations (Scopus)

Ectopic B-Raf expression enhances extracellular signal-regulated kinase (ERK) signaling in T cells and prevents antigen-presenting cell-induced anergy

Dillon, T. J., Karpitski, V., Wetzel, S. A., Parker, D., Shaw, A. S. & Stork, P., Sep 19 2003, In : Journal of Biological Chemistry. 278, 38, p. 35940-35949 10 p.

Research output: Contribution to journalArticle

T-cells
Extracellular Signal-Regulated MAP Kinases
Antigen-Presenting Cells
Chemical activation
T-Lymphocytes
109 Citations (Scopus)

Ectopic release of synaptic vesicles

Matsui, K. & Jahr, C., Dec 18 2003, In : Neuron. 40, 6, p. 1173-1183 11 p.

Research output: Contribution to journalArticle

Synaptic Vesicles
Neuroglia
Exocytosis
Synaptic Membranes
Cerebellar Cortex
50 Citations (Scopus)

Examining the mechanism of Erk nuclear translocation using green fluorescent protein

Horgan, A. & Stork, P., May 1 2003, In : Experimental Cell Research. 285, 2, p. 208-220 13 p.

Research output: Contribution to journalArticle

Green Fluorescent Proteins
PC12 Cells
Nerve Growth Factor
Mitogen-Activated Protein Kinases
Cytoplasm
4 Citations (Scopus)
Electric Capacitance
Neurological Models
Hippocampal Mossy Fibers
Long-Term Potentiation
Exocytosis
88 Citations (Scopus)
Mitogen-Activated Protein Kinase 6
Somatomedins
Cardiac Myocytes
Sheep
Phosphotransferases
175 Citations (Scopus)

Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP

Zhang, Q., Yoshimatsu, Y., Hildebrand, J., Frisch, S. M. & Goodman, R., Oct 17 2003, In : Cell. 115, 2, p. 177-186 10 p.

Research output: Contribution to journalArticle

Homeodomain Proteins
Co-Repressor Proteins
Protein Kinases
Down-Regulation
Apoptosis
129 Citations (Scopus)

Imaging calcium entry sites and ribbon structures in two presynaptic cells

Zenisek, D., Davila, V., Wan, L. & Almers, W., Apr 1 2003, In : Journal of Neuroscience. 23, 7, p. 2538-2548 11 p.

Research output: Contribution to journalArticle

Calcium
Cell Count
Neurons
Rana catesbeiana
Goldfish

Imaging clathrin mediated endocytosis in action

Merrifield, C. J., Feldman, M. & Almers, W., 2003, In : Microscopy and Microanalysis. 9, SUPPL. 2, p. 1322-1323 2 p.

Research output: Contribution to journalArticle

Imaging techniques
219 Citations (Scopus)

International Union of Pharmacology. XLI. Compendium of Voltage-Gated Ion Channels: Potassium Channels

Gutman, G. A., Chandy, K. G., Adelman, J., Aiyar, J., Bayliss, D. A., Clapham, D. E., Covarriubias, M., Desir, G. V., Furuichi, K., Ganetzky, B., Garcia, M. L., Grissmer, S., Jan, L. Y., Karschin, A., Kim, D., Kuperschmidt, S., Kurachi, Y., Lazdunski, M., Lesage, F., Lester, H. A. & 14 others, McKinnon, D., Nichols, C. G., O'Kelly, I., Robbins, J., Robertson, G. A., Rudy, B., Sanguinetti, M., Seino, S., Stuehmer, W., Tamkun, M. M., Vandenberg, C. A., Wei, A., Wulff, H. & Wymore, R. S., Dec 2003, In : Pharmacological Reviews. 55, 4, p. 583-586 4 p.

Research output: Contribution to journalArticle

Voltage-Gated Potassium Channels
Potassium Channels
Ion Channels
Terminology
Pharmacology
4 Citations (Scopus)

It takes two to tango, but three to ISA

Herson, P. S. & Adelman, J., Feb 6 2003, In : Neuron. 37, 3, p. 370-372 3 p.

Research output: Contribution to journalArticle

Potassium Channels
Cerebellum
Neurons
Proteins
1,3-dipropyl-8-phenylxanthine
9 Citations (Scopus)

Presynaptic impairment of synaptic transmission in Drosophila embryos lacking Gsα

Hou, D., Suzuki, K., Wolfgang, W. J., Clay, C., Forte, M. & Kidokoro, Y., Jul 1 2003, In : Journal of Neuroscience. 23, 13, p. 5897-5905 9 p.

Research output: Contribution to journalArticle

Synaptic Transmission
Drosophila
Embryonic Structures
Adenylyl Cyclases
Synapses
53 Citations (Scopus)

Receptor occupancy limits synaptic depression at climbing fiber synapses

Harrison, J. & Jahr, C., Jan 15 2003, In : Journal of Neuroscience. 23, 2, p. 377-383 7 p.

Research output: Contribution to journalArticle

AMPA Receptors
Synapses
Neuroglia
Glutamic Acid
Amino Acid Transport System X-AG
54 Citations (Scopus)

Regulation of backpropagating action potentials in mitral cell lateral dendrites by A-type potassium currents

Christie, J. M. & Westbrook, G., May 1 2003, In : Journal of Neurophysiology. 89, 5, p. 2466-2472 7 p.

Research output: Contribution to journalArticle

Dendrites
Action Potentials
Potassium
Olfactory Bulb
Carisoprodol
35 Citations (Scopus)

Response of yeast to the regulated expression of proteins in the Bcl-2 family

Polčic, P. & Forte, M., Sep 1 2003, In : Biochemical Journal. 374, 2, p. 393-402 10 p.

Research output: Contribution to journalArticle

Yeast
Yeasts
Voltage-Dependent Anion Channels
Membranes
Mitochondria
54 Citations (Scopus)

Roles of α1- and α2-adrenoceptors in the nucleus raphe magnus in opioid analgesia and opioid abstinence-induced hyperalgesia

Bie, B., Fields, H. L., Williams, J. & Pan, Z. Z., Aug 27 2003, In : Journal of Neuroscience. 23, 21, p. 7950-7957 8 p.

Research output: Contribution to journalArticle

Hyperalgesia
Analgesia
Adrenergic Receptors
Opioid Analgesics
Pain
270 Citations (Scopus)

Secretory granules are recaptured largely intact after stimulated exocytosis in cultured endocrine cells

Taraska, J. W., Perrais, D., Ohara-Imaizumi, M., Nagamatsu, S. & Almers, W., Feb 18 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 4, p. 2070-2075 6 p.

Research output: Contribution to journalArticle

Endocrine Cells
Exocytosis
Secretory Vesicles
Cultured Cells
Tissue Plasminogen Activator
74 Citations (Scopus)

Small conductance Ca2+-activated K+ channels and calmodulin. Cell surface expression and gating

Lee, W. S., Ngo-Anh, T. J., Bruening-Wright, A., Maylie, J. & Adelman, J., Jul 11 2003, In : Journal of Biological Chemistry. 278, 28, p. 25940-25946 7 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Calmodulin
Coulomb interactions
Static Electricity
51 Citations (Scopus)

Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses

Tamarina, N. A., Wang, Y., Mariotto, L., Kuznetsov, A., Bond, C., Adelman, J. & Philipson, L. H., Aug 1 2003, In : Diabetes. 52, 8, p. 2000-2006 7 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Islets of Langerhans
Apamin
Glucose
Doxycycline
105 Citations (Scopus)

Synapse density regulates independence at unitary inhibitory synapses

Overstreet, L. S. & Westbrook, G., Apr 1 2003, In : Journal of Neuroscience. 23, 7, p. 2618-2626 9 p.

Research output: Contribution to journalArticle

GABA Plasma Membrane Transport Proteins
Synapses
Catalytic Domain
Neurotransmitter Transport Proteins
Interneurons
78 Citations (Scopus)

Synaptic activation of presynaptic glutamate transporter currents in nerve terminals

Palmer, M. J., Taschenberger, H., Hull, C., Tremere, L. & Von Gersdorff, H., Jun 15 2003, In : Journal of Neuroscience. 23, 12, p. 4831-4841 11 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
Glutamic Acid
Exocytosis
Presynaptic Terminals
Anions
111 Citations (Scopus)

Synaptic Cleft Acidification and Modulation of Short-Term Depression by Exocytosed Protons in Retinal Bipolar Cells

Palmer, M. J., Hull, C., Vigh, J. & Von Gersdorff, H., Dec 10 2003, In : Journal of Neuroscience. 23, 36, p. 11332-11341 10 p.

Research output: Contribution to journalArticle

Retinal Bipolar Cells
Exocytosis
Protons
Goldfish
Bicarbonates
40 Citations (Scopus)

The requirement of specific membrane domains for Raf-1 phosphorylation and activation

Carey, K. D., Watson, R. T., Pessin, J. E. & Stork, P., Jan 31 2003, In : Journal of Biological Chemistry. 278, 5, p. 3185-3196 12 p.

Research output: Contribution to journalArticle

Phosphorylation
Tyrosine
Chemical activation
Membranes
Serine
87 Citations (Scopus)

The Voltage-dependent Anion Channel Is the Target for a New Class of Inhibitors of the Mitochondrial Permeability Transition Pore

Cesura, A. M., Pinard, E., Schubenel, R., Goetschy, V., Friedlein, A., Langen, H., Polcic, P., Forte, M., Bernardi, P. & Kemp, J. A., Dec 12 2003, In : Journal of Biological Chemistry. 278, 50, p. 49812-49818 7 p.

Research output: Contribution to journalArticle

Voltage-Dependent Anion Channels
Permeability
Voltage-Dependent Anion Channel 1
Proteins
Affinity Labels
132 Citations (Scopus)

Two intracellular pathways mediate metabotropic glutamate receptor-induced Ca2+ mobilization in dopamine neurons

Morikawa, H., Khodakhah, K. & Williams, J., Jan 1 2003, In : Journal of Neuroscience. 23, 1, p. 149-157 9 p.

Research output: Contribution to journalArticle

Cyclic ADP-Ribose
Metabotropic Glutamate Receptors
Dopaminergic Neurons
Ryanodine Receptor Calcium Release Channel
Neurotransmitter Agents
100 Citations (Scopus)

Urinary bladder instability induced by selective suppression of the murine small conductance calcium-activated potassium (SK3) channel

Herrera, G. M., Pozo, M. J., Zvara, P., Petkov, G. V., Bond, C. T., Adelman, J. & Nelson, M. T., Sep 15 2003, In : Journal of Physiology. 551, 3, p. 893-903 11 p.

Research output: Contribution to journalArticle

Small-Conductance Calcium-Activated Potassium Channels
Urinary Bladder
Smooth Muscle
Pressure
Muscle Cells
2004
19 Citations (Scopus)

Activation kinetics of the slow afterhyperpolarization in hippocampal CA1 neurons

Gerlach, A. C., Maylie, J. & Adelman, J., May 2004, In : Pflugers Archiv European Journal of Physiology. 448, 2, p. 187-196 10 p.

Research output: Contribution to journalArticle

Action Potentials
Neurons
Chemical activation
Kinetics
Electric potential
151 Citations (Scopus)

A Transgenic Marker for Newly Born Granule Cells in Dentate Gyrus

Overstreet, L. S., Hentges, S. T., Bumaschny, V. F., De Souza, F. S. J., Smart, J. L., Santangelo, A. M., Low, M. J., Westbrook, G. & Rubinstein, M., Mar 31 2004, In : Journal of Neuroscience. 24, 13, p. 3251-3259 9 p.

Research output: Contribution to journalArticle

Dentate Gyrus
Pro-Opiomelanocortin
Neurons
Neurogenesis
Sequence Deletion
94 Citations (Scopus)

Bilayers merge even when exocytosis is transient

Taraska, J. W. & Almers, W., Jun 8 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 23, p. 8780-8785 6 p.

Research output: Contribution to journalArticle

Exocytosis
Cell Membrane
Lipids
Synaptic Vesicles
Secretory Vesicles
108 Citations (Scopus)

Cell-type-specific binding of the transcription factor CREB to the cAMP-response element

Cha-Molstad, H., Keller, D. M., Yochum, G. S., Impey, S. & Goodman, R., Sep 14 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 37, p. 13572-13577 6 p.

Research output: Contribution to journalArticle

Cyclic AMP Response Element-Binding Protein
Response Elements
Transcription Factors
Protein Binding
CREB-Binding Protein
48 Citations (Scopus)

Chronic morphine treatment reduces recovery from opioid desensitization

Dang, V. C. & Williams, J., Sep 1 2004, In : Journal of Neuroscience. 24, 35, p. 7699-7706 8 p.

Research output: Contribution to journalArticle

Morphine
Opioid Analgesics
Monensin
Locus Coeruleus
Brain
22 Citations (Scopus)

Cocaine self-administration selectively decreases noradrenergic regulation of metabotropic glutamate receptor-mediated inhibition in dopamine neurons

Paladini, C. A., Mitchell, J. M., Williams, J. & Mark, G., Jun 2 2004, In : Journal of Neuroscience. 24, 22, p. 5209-5215 7 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate Receptors
Self Administration
Dopaminergic Neurons
Cocaine
Drug-Seeking Behavior
567 Citations (Scopus)

Defining the CREB regulon: A genome-wide analysis of transcription factor regulatory regions

Impey, S., McCorkle, S. R., Cha-Molstad, H., Dwyer, J. M., Yochum, G. S., Boss, J. M., McWeeney, S., Dunn, J. J., Mandel, G. & Goodman, R., Dec 29 2004, In : Cell. 119, 7, p. 1041-1054 14 p.

Research output: Contribution to journalArticle

Regulon
Nucleic Acid Regulatory Sequences
Chromatin
Transcription Factors
Genes
68 Citations (Scopus)

Differential control of synaptic and ectopic vesicular release of glutamate

Matsui, K. & Jahr, C., Oct 13 2004, In : Journal of Neuroscience. 24, 41, p. 8932-8939 8 p.

Research output: Contribution to journalArticle

Neuroglia
Glutamic Acid
AMPA Receptors
Synapses
Amino Acid Transport System X-AG
11 Citations (Scopus)

Expression of connexins during development and following manipulation of afferent input in the rat locus coeruleus

Van Bockstaele, E. J., Garcia-Hernandez, F., Fox, K., Alvarez, V. A. & Williams, J., Jul 2004, In : Neurochemistry International. 45, 2-3, p. 421-428 8 p.

Research output: Contribution to journalArticle

Connexins
Locus Coeruleus
Connexin 43
Neuroglia
Proteins
46 Citations (Scopus)

Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal

Hull, C. & Von Gersdorff, H., Oct 28 2004, In : Neuron. 44, 3, p. 469-482 14 p.

Research output: Contribution to journalArticle

Presynaptic Terminals
Endocytosis
gamma-Aminobutyric Acid
Chlorides
Synapses
51 Citations (Scopus)

GABAergic neurons participate in the brain's response to birdsong auditory stimulation

Pinaud, R., Velho, T. A. F., Jeong, J. K., Tremere, L. A., Leão, R. M., Von Gersdorff, H. & Mello, C., Sep 2004, In : European Journal of Neuroscience. 20, 5, p. 1318-1330 13 p.

Research output: Contribution to journalArticle

Acoustic Stimulation
GABAergic Neurons
Music
Brain
Cell Count
106 Citations (Scopus)

GABA Release from Proopiomelanocortin Neurons

Hentges, S. T., Nishiyama, M., Overstreet, L. S., Stenzel-Poore, M., Williams, J. & Low, M. J., Feb 18 2004, In : Journal of Neuroscience. 24, 7, p. 1578-1583 6 p.

Research output: Contribution to journalArticle

Pro-Opiomelanocortin
gamma-Aminobutyric Acid
Neurons
Neurotransmitter Agents
Eating
2 Citations (Scopus)

Making scents olfactory adaptation

Adelman, J. & Herson, P. S., Jul 2004, In : Nature Neuroscience. 7, 7, p. 689-690 2 p.

Research output: Contribution to journalArticle

Cyclic Nucleotide-Gated Cation Channels
Calmodulin
Binding Sites
Calcium
Neurons
155 Citations (Scopus)

Neural Wiskott Aldrich Syndrome Protein (N-WASP) and the Arp 2/3 complex are recruited to sites of clathrin-mediated endocytosis in cultured fibroblasts

Merrifield, C. J., Qualmann, B., Kessels, M. M. & Almers, W., 2004, In : European Journal of Cell Biology. 83, 1, p. 13-18 6 p.

Research output: Contribution to journalArticle

Wiskott-Aldrich Syndrome Protein
Clathrin
Actin-Related Protein 2-3 Complex
Endocytosis
Fibroblasts