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2008

Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer

Whorton, M. R., Jastrzebska, B., Park, P. S. H., Fotiadis, D., Engel, A., Palczewski, K. & Sunahara, R. K., Feb 15 2008, In : Journal of Biological Chemistry. 283, 7, p. 4387-4394 8 p.

Research output: Contribution to journalArticle

209 Scopus citations

Expression of the SK2 calcium-activated potassium channel is required for cholinergic function in mouse cochlear hair cells

Kong, J. H., Adelman, J. P. & Fuchs, P. A., Nov 15 2008, In : Journal of Physiology. 586, 22, p. 5471-5485 15 p.

Research output: Contribution to journalArticle

31 Scopus citations

Functional roles of a Ca2+ -activated K+ channel in atrioventricular nodes

Zhang, Q., Timofeyev, V., Lu, L., Li, N., Singapuri, A., Long, M. K., Bond, C. T., Adelman, J. P. & Chiamvimonvat, N., Feb 1 2008, In : Circulation research. 102, 4, p. 465-471 7 p.

Research output: Contribution to journalArticle

71 Scopus citations

Function of neuromuscular synapses in the zebrafish choline- acetyltransferase mutant bajan

Wang, M., Wen, H. & Brehm, P., Oct 1 2008, In : Journal of neurophysiology. 100, 4, p. 1995-2004 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Heterogeneous Ca2+ influx along the adult calyx of held: A structural and computational study

Spirou, G. A., Chirila, F. V., von Gersdorff, H. & Manis, P. B., Jun 12 2008, In : Neuroscience. 154, 1, p. 171-185 15 p.

Research output: Contribution to journalArticle

17 Scopus citations

Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels

Chiara, F., Castellaro, D., Marin, O., Petronilli, V., Brusilow, W. S., Juhaszova, M., Sollott, S. J., Forte, M., Bernardi, P. & Rasola, A., Mar 19 2008, In : PloS one. 3, 3, e1852.

Research output: Contribution to journalArticle

183 Scopus citations

Light regulation of Ca2+ in the cone photoreceptor synaptic terminal

Choi, S. Y., Jackman, S., Thoreson, W. B. & Kramer, R. H., Sep 1 2008, In : Visual neuroscience. 25, 5-6, p. 693-700 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Morphine produces circuit-specific neuroplasticity in the bed nucleus of the stria terminalis

Dumont, É. C., Rycroft, B. K., Maiz, J. & Williams, J. T., Apr 22 2008, In : Neuroscience. 153, 1, p. 232-239 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Neurotransmitter Modulation of Small-Conductance Ca2+-Activated K+ Channels by Regulation of Ca2+ Gating

Maingret, F., Coste, B., Hao, J., Giamarchi, A., Allen, D., Crest, M., Litchfield, D. W., Adelman, J. P. & Delmas, P., Aug 14 2008, In : Neuron. 59, 3, p. 439-449 11 p.

Research output: Contribution to journalArticle

53 Scopus citations

Neurotrophin-dependent dendritic filopodial motility: A convergence on PI3K signaling

Luikart, B. W., Zhang, W., Wayman, G. A., Kwon, C. H., Westbrook, G. L. & Parada, L. F., Jul 2 2008, In : Journal of Neuroscience. 28, 27, p. 7006-7012 7 p.

Research output: Contribution to journalArticle

76 Scopus citations

Organization and function of the blood-brain barrier in Drosophila

Stork, T., Engelen, D., Krudewig, A., Silies, M., Bainton, R. J. & Klämbt, C., Jan 16 2008, In : Journal of Neuroscience. 28, 3, p. 587-597 11 p.

Research output: Contribution to journalArticle

Open Access
191 Scopus citations

Phosphate is essential for inhibition of the mitochondrial permeability transition pore by cyclosporin A and by cyclophilin D ablation

Basso, E., Petronilli, V., Forte, M. A. & Bernardi, P., Sep 26 2008, In : Journal of Biological Chemistry. 283, 39, p. 26307-26311 5 p.

Research output: Contribution to journalArticle

126 Scopus citations

Pre- and postsynaptic regulation of locus coeruleus neurons after chronic morphine treatment: A study of GIRK-knockout mice

Torrecilla, M., Quillinan, N., Williams, J. T. & Wickman, K., Aug 1 2008, In : European Journal of Neuroscience. 28, 3, p. 618-624 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Protein kinase C modulates synaptic vesicle acidification in a ribbon type nerve terminal in the retina

Abreu, B. J., Guimarães, M., Uliana, L. C., Vigh, J., von Gersdorff, H., Prado, M. A. & Guatimosim, C., Nov 1 2008, In : Neurochemistry International. 53, 5, p. 155-164 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Ras is required for the cyclic AMP-dependent activation of Rap1 via Epac2

Liu, C., Takahashi, M., Li, Y., Song, S., Dillon, T. J., Shinde, U. & Stork, P. J. S., Dec 1 2008, In : Molecular and cellular biology. 28, 23, p. 7109-7125 17 p.

Research output: Contribution to journalArticle

41 Scopus citations

Regulation of postsynaptic RapGAP SPAR by polo-like kinase 2 and the SCFβ-TRCP ubiquitin ligase in hippocampal neurons

Ang, X. L., Seeburg, D. P., Sheng, M. & Harper, J. W., Oct 24 2008, In : Journal of Biological Chemistry. 283, 43, p. 29424-29432 9 p.

Research output: Contribution to journalArticle

43 Scopus citations

Release of the styryl dyes from single synaptic vesicles in hippocampal neurons

Chen, X., Barg, S. & Almers, W., Feb 20 2008, In : Journal of Neuroscience. 28, 8, p. 1894-1903 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation

Westbrook, T. F., Hu, G., Ang, X. L., Mulligan, P., Pavlova, N. N., Liang, A., Leng, Y., Maehr, R., Shi, Y., Harper, J. W. & Elledge, S. J., Mar 20 2008, In : Nature. 452, 7185, p. 370-374 5 p.

Research output: Contribution to journalArticle

231 Scopus citations

SK2 channel plasticity contributes to LTP at Schaffer collateral-CA1 synapses

Lin, M. T., Luján, R., Watanabe, M., Adelman, J. P. & Maylie, J., Feb 1 2008, In : Nature Neuroscience. 11, 2, p. 170-177 8 p.

Research output: Contribution to journalArticle

152 Scopus citations

SK3 K+ channel-deficient mice have enhanced dopamine and serotonin release and altered emotional behaviors

Jacobsen, J. P. R., Weikop, P., Hansen, H. H., Mikkelsen, J. D., Redrobe, J. P., Holst, D., Bond, C. T., Adelman, J. P., Christophersen, P. & Mirza, N. R., Nov 1 2008, In : Genes, Brain and Behavior. 7, 8, p. 836-848 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Small-conductance, Ca2+-activated K+ channel 2 is the key functional component of SK channels in mouse urinary bladder

Thorneloe, K. S., Knorn, A. M., Doetsch, P. E., Lashinger, E. S. R., Liu, A. X., Bond, C. T., Adelman, J. P. & Nelson, M. T., May 1 2008, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 294, 5, p. R1737-R1743

Research output: Contribution to journalArticle

35 Scopus citations

Synaptic homeostasis in a zebrafish glial glycine transporter mutant

Mongeon, R., Gleason, M. R., Masino, M. A., Fetcho, J. R., Mandel, G., Brehm, P. & Dallman, J. E., Oct 1 2008, In : Journal of neurophysiology. 100, 4, p. 1716-1723 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Synaptic vesicle endocytosis: fast and slow modes of membrane retrieval

Smith, S. M., Renden, R. & von Gersdorff, H., Nov 1 2008, In : Trends in Neurosciences. 31, 11, p. 559-568 10 p.

Research output: Contribution to journalArticle

102 Scopus citations

The pool of fast releasing vesicles is augmented by myosin light chain kinase inhibition at the calyx of held synapse

Srinivasan, G., Jun, H. K. & Von Gersdorff, H., Apr 2008, In : Journal of neurophysiology. 99, 4, p. 1810-1824 15 p.

Research output: Contribution to journalArticle

46 Scopus citations

The spread of Ras activity triggered by activation of a single dendritic spine

Harvey, C. D., Yasuda, R., Zhong, H. & Svoboda, K., Jul 4 2008, In : Science. 321, 5885, p. 136-140 5 p.

Research output: Contribution to journalArticle

275 Scopus citations

T-type Ca2+ channels, SK2 channels and SERCAs gate sleep-related oscillations in thalamic dendrites

Cueni, L., Canepari, M., Luján, R., Emmenegger, Y., Watanabe, M., Bond, C. T., Franken, P., Adelman, J. P. & Lüthi, A., Jun 1 2008, In : Nature Neuroscience. 11, 6, p. 683-692 10 p.

Research output: Contribution to journalArticle

134 Scopus citations
2007

A biochemical approach to identifying microRNA targets

Karginov, F. V., Conaco, C., Xuan, Z., Schmidt, B. H., Parker, J. S., Mandel, G. & Hannon, G. J., Dec 4 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 49, p. 19291-19296 6 p.

Research output: Contribution to journalArticle

294 Scopus citations

A CE assay for the detection of agonist-stimulated adenylyl cyclase activity

Cunliffe, J. M., Whorton, M. R., Sunahara, R. K. & Kennedy, R. T., Jun 1 2007, In : ELECTROPHORESIS. 28, 12, p. 1913-1920 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

A conformation change in the extracellular domain that accompanies desensitization of acid-sensing ion channel (ASIC) 3

Cushman, K. A., Marsh-Haffner, J., Adelman, J. P. & McCleskey, E. W., Apr 1 2007, In : Journal of General Physiology. 129, 4, p. 345-350 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein

Whorton, M. R., Bokoch, M. P., Rasmussen, S. G. F., Huang, B., Zare, R. N., Kobilka, B. & Sunahara, R. K., May 1 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 18, p. 7682-7687 6 p.

Research output: Contribution to journalArticle

518 Scopus citations

An antisense transcript induced by Wnt/β-catenin signaling decreases E2F4

Yochum, G. S., Cleland, R., McWeeney, S. & Goodman, R. H., Jan 12 2007, In : Journal of Biological Chemistry. 282, 2, p. 871-878 8 p.

Research output: Contribution to journalArticle

46 Scopus citations

Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities

Stegmeier, F., Rape, M., Draviam, V. M., Nalepa, G., Sowa, M. E., Ang, X. L., McDonald, E. R., Li, M. Z., Hannon, G. J., Sorger, P. K., Kirschner, M. W., Harper, J. W. & Elledge, S. J., Apr 19 2007, In : Nature. 446, 7138, p. 876-881 6 p.

Research output: Contribution to journalArticle

277 Scopus citations

A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions

Otto, S. J., McCorkle, S. R., Hover, J., Conaco, C., Han, J. J., Impey, S., Yochum, G. S., Dunn, J. J., Goodman, R. H. & Mandel, G., Jun 20 2007, In : Journal of Neuroscience. 27, 25, p. 6729-6739 11 p.

Research output: Contribution to journalArticle

169 Scopus citations

Antidepressant binding site in a bacterial homologue of neurotransmitter transporters

Singh, S. K., Yamashita, A. & Gouaux, E., Aug 23 2007, In : Nature. 448, 7156, p. 952-956 5 p.

Research output: Contribution to journalArticle

313 Scopus citations

Apoptosome dependent caspase-3 activation pathway is non-redundant and necessary for apoptosis in sympathetic neurons

Wright, K. M., Vaughn, A. E. & Deshmukh, M., Mar 1 2007, In : Cell Death and Differentiation. 14, 3, p. 625-633 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

C2H2 zinc finger-SET histone methyltransferase is a plant-specific chromatin modifier

Krichevsky, A., Gutgarts, H., Kozlovsky, S. V., Tzfira, T., Sutton, A., Sternglanz, R., Mandel, G. & Citovsky, V., Mar 1 2007, In : Developmental Biology. 303, 1, p. 259-269 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy

Keller, D. M., McWeeney, S., Arsenlis, A., Drouin, J., Wright, C. V. E., Wang, H., Wollheim, C. B., White, P., Kaestner, K. H. & Goodman, R. H., Nov 2 2007, In : Journal of Biological Chemistry. 282, 44, p. 32084-32092 9 p.

Research output: Contribution to journalArticle

79 Scopus citations

Chromatin modification of Apaf-1 restricts the apoptotic pathway in mature neurons

Wright, K. M., Smith, M. I., Farrag, L. & Deshmukh, M., Dec 3 2007, In : Journal of Cell Biology. 179, 5, p. 825-832 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter

Boudker, O., Ryan, R. M., Yernool, D., Shimamoto, K. & Gouaux, E., Jan 25 2007, In : Nature. 445, 7126, p. 387-393 7 p.

Research output: Contribution to journalArticle

330 Scopus citations

Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis

Forte, M., Gold, B. G., Marracci, G., Chaudhary, P., Basso, E., Johnsen, D., Yu, X., Fowlkes, J., Bernardi, P. & Bourdette, D., May 1 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 18, p. 7558-7563 6 p.

Research output: Contribution to journalArticle

151 Scopus citations

Decreased vesicular somatodendritic dopamine stores in leptin-deficient mice

Roseberry, A. G., Painter, T., Mark, G. P. & Williams, J. T., Jun 27 2007, In : Journal of Neuroscience. 27, 26, p. 7021-7027 7 p.

Research output: Contribution to journalArticle

45 Scopus citations

Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues

Johnson, C. E., Huang, Y. Y., Parrish, A. B., Smith, M. I., Vaughn, A. E., Zhang, Q., Wright, K. M., Van Dyke, T., Wechsler-Reya, R. J., Kornbluth, S. & Deshmukh, M., Dec 26 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 52, p. 20820-20825 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Distinct functions of α-spectrin and β-spectrin during axonal pathfinding

Hülsmeier, J., Pielage, J., Rickert, C., Technau, G. M., Klämbt, C. & Stork, T., Feb 1 2007, In : Development. 134, 4, p. 713-722 10 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

Distribution of menin-occupied regions in chromatin specifies a broad role of menin in transcriptional regulation

Agarwal, S. K., Impey, S., McWeeney, S., Scacheri, P. C., Collins, F. S., Goodman, R. H., Spiegel, A. M. & Marx, S. J., Feb 2007, In : Neoplasia. 9, 2, p. 101-107 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

Disynaptic amplification of metabotropic glutamate receptor 1 responses in the olfactory bulb

De Saint Jan, D. & Westbrook, G. L., Jan 3 2007, In : Journal of Neuroscience. 27, 1, p. 132-140 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Evidence for a deep pore activation gate in small conductance Ca 2+-activated K+ channels

Bruening-Wright, A., Lee, W. S., Adelman, J. P. & Maylie, J., Dec 1 2007, In : Journal of General Physiology. 130, 6, p. 601-610 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

Extracellular glutamate concentration in hippocampal slice

Herman, M. A. & Jahr, C. E., Sep 5 2007, In : Journal of Neuroscience. 27, 36, p. 9736-9741 6 p.

Research output: Contribution to journalArticle

223 Scopus citations

Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems

Wu, H. Y., Hsu, F. C., Gleichman, A. J., Baconguis, I., Coulter, D. A. & Lynch, D. R., Jul 13 2007, In : Journal of Biological Chemistry. 282, 28, p. 20075-20087 13 p.

Research output: Contribution to journalArticle

62 Scopus citations

Genetic deletion of SK2 channels in mouse inner hair cells prevents the developmental linearization in the Ca2+ dependence of exocytosis

Johnson, S. L., Adelman, J. P. & Marcotti, W., Sep 1 2007, In : Journal of Physiology. 583, 2, p. 631-646 16 p.

Research output: Contribution to journalArticle

40 Scopus citations

Glial cell migration in the eye disc

Silies, M., Yuva, Y., Engelen, D., Aho, A., Stork, T. & Klämbt, C., Nov 28 2007, In : Journal of Neuroscience. 27, 48, p. 13130-13139 10 p.

Research output: Contribution to journalArticle

Open Access
58 Scopus citations