Research Output 1987 2020

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2008
26 Citations (Scopus)

SK3 K+ channel-deficient mice have enhanced dopamine and serotonin release and altered emotional behaviors

Jacobsen, J. P. R., Weikop, P., Hansen, H. H., Mikkelsen, J. D., Redrobe, J. P., Holst, D., Bond, C. T., Adelman, J., Christophersen, P. & Mirza, N. R., Nov 2008, In : Genes, Brain and Behavior. 7, 8, p. 836-848 13 p.

Research output: Contribution to journalArticle

Dopamine
Serotonin
Synaptic Transmission
Hindlimb Suspension
Corpus Striatum
34 Citations (Scopus)

Small-conductance, Ca2+-activated K+ channel 2 is the key functional component of SK channels in mouse urinary bladder

Thorneloe, K. S., Knorn, A. M., Doetsch, P. E., Lashinger, E. S. R., Liu, A. X., Bond, C. T., Adelman, J. & Nelson, M. T., May 2008, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 294, 5

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Urinary Bladder
Apamin
Smooth Muscle
Galactosidases
22 Citations (Scopus)

Synaptic homeostasis in a zebrafish glial glycine transporter mutant

Mongeon, R., Gleason, M. R., Masino, M. A., Fetcho, J. R., Mandel, G., Brehm, P. & Dallman, J. E., Oct 2008, In : Journal of Neurophysiology. 100, 4, p. 1716-1723 8 p.

Research output: Contribution to journalArticle

Glycine Plasma Membrane Transport Proteins
Zebrafish
Neuroglia
Glycine
Homeostasis
99 Citations (Scopus)

Synaptic vesicle endocytosis: fast and slow modes of membrane retrieval

Smith, S., Renden, R. & Von Gersdorff, H., Nov 2008, In : Trends in Neurosciences. 31, 11, p. 559-568 10 p.

Research output: Contribution to journalArticle

Synaptic Vesicles
Endocytosis
Exocytosis
Membranes
Flicker Fusion
45 Citations (Scopus)

The pool of fast releasing vesicles is augmented by myosin light chain kinase inhibition at the calyx of held synapse

Srinivasan, G., Jun, H. K. & Von Gersdorff, H., Apr 2008, In : Journal of Neurophysiology. 99, 4, p. 1810-1824 15 p.

Research output: Contribution to journalArticle

Myosin-Light-Chain Kinase
Synapses
Excitatory Postsynaptic Potentials
Transport Vesicles
Cytoskeletal Proteins
131 Citations (Scopus)

T-type Ca2+ channels, SK2 channels and SERCAs gate sleep-related oscillations in thalamic dendrites

Cueni, L., Canepari, M., Luján, R., Emmenegger, Y., Watanabe, M., Bond, C. T., Franken, P., Adelman, J. & Lüthi, A., Jun 2008, In : Nature Neuroscience. 11, 6, p. 683-692 10 p.

Research output: Contribution to journalArticle

Sarcoplasmic Reticulum Calcium-Transporting ATPases
Dendrites
Sleep
Thalamus
Eye Movements
3 Citations (Scopus)

Ultraweak Signals Can Cause Synaptic Depression and Adaptation

Demb, J. B. & Von Gersdorff, H., Mar 27 2008, In : Neuron. 57, 6, p. 802-804 3 p.

Research output: Contribution to journalArticle

Synapses
Photons
Retina
Neurons
Light
2007
291 Citations (Scopus)

A biochemical approach to identifying microRNA targets

Karginov, F. V., Conaco, C., Xuan, Z., Schmidt, B. H., Parker, J. S., Mandel, G. & Hannon, G. J., Dec 4 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 49, p. 19291-19296 6 p.

Research output: Contribution to journalArticle

RNA-Induced Silencing Complex
MicroRNAs
Messenger RNA
Microarray Analysis
Seeds
49 Citations (Scopus)

A conformation change in the extracellular domain that accompanies desensitization of acid-sensing ion channel (ASIC) 3

Cushman, K. A., Marsh-Haffner, J., Adelman, J. & McCleskey, E. W., Apr 2007, In : Journal of General Physiology. 129, 4, p. 345-350 6 p.

Research output: Contribution to journalArticle

Acid Sensing Ion Channels
Cysteine
Acidic Amino Acids
Epithelial Sodium Channels
Mutation
45 Citations (Scopus)

An antisense transcript induced by Wnt/β-catenin signaling decreases E2F4

Yochum, G. S., Cleland, R., McWeeney, S. & Goodman, R., Jan 12 2007, In : Journal of Biological Chemistry. 282, 2, p. 871-878 8 p.

Research output: Contribution to journalArticle

Catenins
Genes
3' Untranslated Regions
Binding Sites
Cells
165 Citations (Scopus)

A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions

Otto, S. J., McCorkle, S. R., Hover, J., Conaco, C., Han, J. J., Impey, S., Yochum, G. S., Dunn, J. J., Goodman, R. & Mandel, G., Jun 20 2007, In : Journal of Neuroscience. 27, 25, p. 6729-6739 11 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Transcriptional Silencer Elements
Genes
Nerve Tissue
Neuroendocrine Tumors
308 Citations (Scopus)

Antidepressant binding site in a bacterial homologue of neurotransmitter transporters

Singh, S. K., Yamashita, A. & Gouaux, E., Aug 23 2007, In : Nature. 448, 7156, p. 952-956 5 p.

Research output: Contribution to journalArticle

Neurotransmitter Transport Proteins
Antidepressive Agents
Clomipramine
Sodium
Binding Sites
74 Citations (Scopus)

Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy

Keller, D. M., McWeeney, S., Arsenlis, A., Drouin, J., Wright, C. V. E., Wang, H., Wollheim, C. B., White, P., Kaestner, K. H. & Goodman, R., Nov 2 2007, In : Journal of Biological Chemistry. 282, 44, p. 32084-32092 9 p.

Research output: Contribution to journalArticle

Microarray Analysis
Microarrays
Chromatin
Transcription Factors
Genes
323 Citations (Scopus)

Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter

Boudker, O., Ryan, R. M., Yernool, D., Shimamoto, K. & Gouaux, E., Jan 25 2007, In : Nature. 445, 7126, p. 387-393 7 p.

Research output: Contribution to journalArticle

Aspartic Acid
Sodium
Ions
Binding Sites
Lipid Bilayers
151 Citations (Scopus)

Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis

Forte, M., Gold, B. G., Marracci, G., Chaudhary, P., Basso, E., Johnsen, D., Yu, X., Fowlkes, J., Bernardi, P. & Bourdette, D., May 1 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 18, p. 7558-7563 6 p.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Multiple Sclerosis
Axons
Animal Models
Inflammation
43 Citations (Scopus)

Decreased vesicular somatodendritic dopamine stores in leptin-deficient mice

Roseberry, A. G., Painter, T., Mark, G. & Williams, J., Jun 27 2007, In : Journal of Neuroscience. 27, 26, p. 7021-7027 7 p.

Research output: Contribution to journalArticle

Leptin
Dopamine
Cocaine
Colforsin
Wild Animals
39 Citations (Scopus)

Distribution of menin-occupied regions in chromatin specifies a broad role of menin in transcriptional regulation

Agarwal, S. K., Impey, S., McWeeney, S., Scacheri, P. C., Collins, F. S., Goodman, R., Spiegel, A. M. & Marx, S. J., Feb 2007, In : Neoplasia. 9, 2, p. 101-107 7 p.

Research output: Contribution to journalArticle

Chromatin
Multiple Endocrine Neoplasia Type 1
Genes
Genome
Chromatin Immunoprecipitation
33 Citations (Scopus)

Disynaptic amplification of metabotropic glutamate receptor 1 responses in the olfactory bulb

De Saint Jan, D. & Westbrook, G., Jan 3 2007, In : Journal of Neuroscience. 27, 1, p. 132-140 9 p.

Research output: Contribution to journalArticle

Excitatory Postsynaptic Potentials
Olfactory Bulb
Metabotropic Glutamate Receptors
N-Methyl-D-Aspartate Receptors
Glutamic Acid
2 Citations (Scopus)

Endocannabinoids Mediate Synaptic Plasticity at Mixed Synapses

Vigh, J. & Von Gersdorff, H., Dec 20 2007, In : Neuron. 56, 6, p. 945-946 2 p.

Research output: Contribution to journalArticle

Endocannabinoids
Neuronal Plasticity
Synapses
Electrical Synapses
Gap Junctions
1 Citation (Scopus)
Autoimmune Experimental Encephalomyelitis
Multiple Sclerosis
Axons
Animal Models
cyclophilin D
37 Citations (Scopus)

Evidence for a deep pore activation gate in small conductance Ca 2+-activated K+ channels

Bruening-Wright, A., Lee, W. S., Adelman, J. & Maylie, J., Dec 2007, In : Journal of General Physiology. 130, 6, p. 601-610 10 p.

Research output: Contribution to journalArticle

Intracellular Membranes
Cysteine
Small-Conductance Calcium-Activated Potassium Channels
Calcium
Voltage-Gated Potassium Channels
216 Citations (Scopus)

Extracellular glutamate concentration in hippocampal slice

Herman, M. A. & Jahr, C., Sep 5 2007, In : Journal of Neuroscience. 27, 36, p. 9736-9741 6 p.

Research output: Contribution to journalArticle

Glutamic Acid
N-Methyl-D-Aspartate Receptors
Neurons
Pyramidal Cells
Exocytosis
40 Citations (Scopus)

Genetic deletion of SK2 channels in mouse inner hair cells prevents the developmental linearization in the Ca2+ dependence of exocytosis

Johnson, S. L., Adelman, J. & Marcotti, W., Sep 1 2007, In : Journal of Physiology. 583, 2, p. 631-646 16 p.

Research output: Contribution to journalArticle

Inner Auditory Hair Cells
Exocytosis
Action Potentials
Cochlea
Hearing
68 Citations (Scopus)

Glutamatergic and purinergic receptor-mediated calcium transients in bergmann glial cells

Piet, R. & Jahr, C., Apr 11 2007, In : Journal of Neuroscience. 27, 15, p. 4027-4035 9 p.

Research output: Contribution to journalArticle

Purinergic Receptors
AMPA Receptors
Purkinje Cells
Neuroglia
Astrocytes
336 Citations (Scopus)

Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA

Klein, M. E., Lioy, D. T., Ma, L., Impey, S., Mandel, G. & Goodman, R., Dec 2007, In : Nature Neuroscience. 10, 12, p. 1513-1514 2 p.

Research output: Contribution to journalArticle

Methyl-CpG-Binding Protein 2
MicroRNAs
Brain-Derived Neurotrophic Factor
Protein Biosynthesis
Neurons
42 Citations (Scopus)

Kappa opioid inhibition of somatodendritic dopamine inhibitory postsynaptic currents

Ford, C. P., Beckstead, M. J. & Williams, J., Jan 2007, In : Journal of Neurophysiology. 97, 1, p. 883-891 9 p.

Research output: Contribution to journalArticle

Inhibitory Postsynaptic Potentials
Opioid Analgesics
Dopamine
Ventral Tegmental Area
kappa Opioid Receptor
40 Citations (Scopus)

Long-term depression of a dopamine IPSC

Beckstead, M. J. & Williams, J., Feb 21 2007, In : Journal of Neuroscience. 27, 8, p. 2074-2080 7 p.

Research output: Contribution to journalArticle

Dopamine
Dopaminergic Neurons
Corpus Striatum
Dendrites
Mesencephalon
140 Citations (Scopus)

Metabolic regulation of SIRT1 transcription via a HIC1: CtBP corepressor complex

Zhang, Q., Wang, S. Y., Fleuriel, C., Leprince, D., Rocheleau, J. V., Piston, D. W. & Goodman, R., Jan 16 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 3, p. 829-833 5 p.

Research output: Contribution to journalArticle

Co-Repressor Proteins
Histone Deacetylases
Deoxyglucose
NAD
Oxidation-Reduction
30 Citations (Scopus)

Myometrial expression of small conductance Ca2+-activated K + channels depresses phasic uterine contraction

Brown, A., Cornwell, T., Korniyenko, I., Solodushko, V., Bond, C. T., Adelman, J. & Taylor, M. S., Feb 2007, In : American Journal of Physiology - Cell Physiology. 292, 2

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Uterine Contraction
Apamin
Oxytocin
Doxycycline
39 Citations (Scopus)

Noradrenergic modulation of the hyperpolarization-activated cation current (Ih) in dopamine neurons of the ventral tegmental area

Arencibia-Albite, F., Paladini, C., Williams, J. & Jiménez-Rivera, C. A., Oct 26 2007, In : Neuroscience. 149, 2, p. 303-314 12 p.

Research output: Contribution to journalArticle

Ventral Tegmental Area
Dopaminergic Neurons
Cations
Norepinephrine
Dopamine
100 Citations (Scopus)

Organization and regulation of small conductance Ca2+-activated K+ channel multiprotein complexes

Allen, D., Fakler, B., Maylie, J. & Adelman, J., Feb 28 2007, In : Journal of Neuroscience. 27, 9, p. 2369-2376 8 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Protein Phosphatase 2
Multiprotein Complexes
Calmodulin
Phosphorylation
19 Citations (Scopus)

Overexpression of SK2 channels enhances efferent suppression of cochlear responses without enhancing noise resistance

Maison, S. F., Parker, L. L., Young, L., Adelman, J., Zuo, J. & Liberman, M. C., Apr 2007, In : Journal of Neurophysiology. 97, 4, p. 2930-2936 7 p.

Research output: Contribution to journalArticle

Cochlea
Outer Auditory Hair Cells
Nicotinic Receptors
Auditory Hair Cells
Calcium-Activated Potassium Channels
79 Citations (Scopus)

Presynaptic Ca2+ buffers control the strength of a fast post-tetanic hyperpolarization mediated by the α3 Na+/K +-ATPase

Kim, J. H., Sizov, I., Dobretsov, M. & Von Gersdorff, H., Feb 2007, In : Nature Neuroscience. 10, 2, p. 196-205 10 p.

Research output: Contribution to journalArticle

Buffers
Neuronal Plasticity
Presynaptic Terminals
Action Potentials
Fluorescent Antibody Technique
20 Citations (Scopus)

Presynaptic regulation of dendrodendritic dopamine transmission

Beckstead, M. J., Ford, C. P., Phillips, P. E. M. & Williams, J., Sep 2007, In : European Journal of Neuroscience. 26, 6, p. 1479-1488 10 p.

Research output: Contribution to journalArticle

Dopamine
Inhibitory Postsynaptic Potentials
Body Regions
Dopaminergic Neurons
Autoreceptors
2 Citations (Scopus)

Putting on the RITz.

Kaech-Petrie, S., Banker, G. & Stork, P., Dec 11 2007, In : Science's STKE : signal transduction knowledge environment. 2007, 416

Research output: Contribution to journalArticle

ras Proteins
Bone Morphogenetic Proteins
Dendrites
Drosophila melanogaster
Transforming Growth Factor beta

Rap1: Selective activator of β2 integrins?

Stork, P., Nov 15 2007, In : Blood. 110, 10, p. 3496-3497 2 p.

Research output: Contribution to journalArticle

Lymphocyte Function-Associated Antigen-1
T-cells
Chemokines
Integrins
Adhesion

Role of cyclophilin D in hypoxia-ischemia induced brain injury during development

Wang, X., Forte, M., Bernardi, P., Rousset, C., Zhu, C., Blomgren, K., Carlsson, Y., Mallard, C. & Hagberg, H., Nov 13 2007, In : Journal of Cerebral Blood Flow and Metabolism. 27, SUPPL. 1

Research output: Contribution to journalArticle

Brain Injuries
Ischemia
Brain
Permeability
Cell Death
77 Citations (Scopus)

Serial analysis of chromatin occupancy identifies β-catenin target genes in colorectal carcinoma cells

Yochum, G. S., McWeeney, S., Rajaraman, V., Cleland, R., Peters, S. & Goodman, R., Feb 27 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 9, p. 3324-3329 6 p.

Research output: Contribution to journalArticle

Catenins
Chromatin
Colorectal Neoplasms
TCF Transcription Factors
Wnt Signaling Pathway
21 Citations (Scopus)

Short-term depression at the reciprocal synapses between a retinal bipolar cell terminal and amacrine cells

Li, G. L., Vigh, J. & Von Gersdorff, H., Jul 11 2007, In : Journal of Neuroscience. 27, 28, p. 7377-7385 9 p.

Research output: Contribution to journalArticle

Retinal Bipolar Cells
Amacrine Cells
Synapses
gamma-Aminobutyric Acid
Glutamic Acid
25 Citations (Scopus)

Stimulated exocytosis of endosomes in goldfish retinal bipolar neurons

Coggins, M. R., Grabner, C. P., Almers, W. & Zenisek, D., Nov 1 2007, In : Journal of Physiology. 584, 3, p. 853-865 13 p.

Research output: Contribution to journalArticle

Retinal Neurons
Goldfish
Endosomes
Exocytosis
Endocytosis
724 Citations (Scopus)

Structure of acid-sensing ion channel 1 at 1.9 Å resolution and low pH

Jasti, J., Furukawa, H., Gonzales, E. B. & Gouaux, E., Sep 20 2007, In : Nature. 449, 7160, p. 316-323 8 p.

Research output: Contribution to journalArticle

Acid Sensing Ion Channels
Protons
Disulfides
Degenerin Sodium Channels
Epithelial Sodium Channels
102 Citations (Scopus)

Synaptic transmission at the calyx of held under in vivo-like activity levels

Hermann, J., Pecka, M., Von Gersdorff, H., Grothe, B. & Klug, A., Aug 2007, In : Journal of Neurophysiology. 98, 2, p. 807-820 14 p.

Research output: Contribution to journalArticle

Synaptic Transmission
Synapses
Gerbillinae
Brain Stem
Auditory Pathways
87 Citations (Scopus)
Synaptic Vesicles
Endocytosis
Exocytosis
Temperature
Synaptic Membranes
45 Citations (Scopus)

The requirement of Ras and Rap1 for the activation of ERKs by cAMP, PACAP, and KCl in cerebellar granule cells

Obara, Y., Horgan, A. & Stork, P., Apr 2007, In : Journal of Neurochemistry. 101, 2, p. 470-482 13 p.

Research output: Contribution to journalArticle

Adenylyl Cyclases
Cyclic AMP
Chemical activation
Protein Kinases
Extracellular Signal-Regulated MAP Kinases
53 Citations (Scopus)

Trace amine-associated receptor 1 displays species-dependent stereoselectivity for isomers of methamphetamine, amphetamine, and Para-hydroxyamphetamine

Reese, E. A., Bunzow, J. R., Arttamangkul, S., Sonders, M. S. & Grandy, D., Apr 2007, In : Journal of Pharmacology and Experimental Therapeutics. 321, 1, p. 178-186 9 p.

Research output: Contribution to journalArticle

p-Hydroxyamphetamine
Methamphetamine
Amphetamine
Amines
Phenethylamines
2006
131 Citations (Scopus)

Delayed development of adult-generated granule cells in dentate gyrus

Overstreet-Wadiche, L. S., Bensen, A. L. & Westbrook, G., Feb 22 2006, In : Journal of Neuroscience. 26, 8, p. 2326-2334 9 p.

Research output: Contribution to journalArticle

Dentate Gyrus
Glutamate Decarboxylase
Brain
gamma-Aminobutyric Acid
Transcriptional Activation
59 Citations (Scopus)

Diurnal changes in exocytosis and the number of synaptic ribbons at active zones of an on-type bipolar cell terminal

Hull, C., Studholme, K., Yazulla, S. & Von Gersdorff, H., Oct 2006, In : Journal of Neurophysiology. 96, 4, p. 2025-2033 9 p.

Research output: Contribution to journalArticle

Exocytosis
Synaptic Vesicles
Nystatin
Photoreceptor Cells
Goldfish

Erratum: The mitochondrial permeability transition from in vitro artifact to disease target (FEBS Journal (2006) 273 (2077-2099))

Bernardi, P., Krauskopf, A., Basso, E., Petronilli, V., Blachly-Dyson, E., Di Lisa, F. & Forte, M., Jun 2006, In : FEBS Journal. 273, 11, p. 2578 1 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Exocytosis unbound

Matsui, K. & Jahr, C., Jun 2006, In : Current Opinion in Neurobiology. 16, 3, p. 305-311 7 p.

Research output: Contribution to journalArticle

Exocytosis
Synapses
Action Potentials
Nervous System
Neurotransmitter Agents
93 Citations (Scopus)

Functional maturation of adult-generated granule cells

Overstreet-Wadiche, L. S. & Westbrook, G., 2006, In : Hippocampus. 16, 3, p. 208-215 8 p.

Research output: Contribution to journalArticle

Neurons