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2009

Crystal structures of catalytic and regulatory subunits of rat protein kinase CK2

Zhou, W. H., Qin, X. H., Yan, X. J., Xie, X. Q., Li, L., Fang, S. S., Long, J. F., Adelman, J., Tang, W. J. & Shen, Y. Q., Jan 1 2009, In : Chinese Science Bulletin. 54, 2, p. 220-226 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Cyclophilin D modulates mitochondrial F0F1-ATP synthase by interacting with the lateral stalk of the complex

Giorgio, V., Bisetto, E., Soriano, M. E., Dabbeni-Sala, F., Basso, E., Petronilli, V., Forte, M. A., Bernardi, P. & Lippe, G., Dec 4 2009, In : Journal of Biological Chemistry. 284, 49, p. 33982-33988 7 p.

Research output: Contribution to journalArticle

186 Scopus citations

Developmental shift of cyclophilin D contribution to hypoxic-ischemic brain injury

Wang, X., Carlsson, Y., Basso, E., Zhu, C., Rousset, C. I., Rasola, A., Johansson, B. R., Blomgren, K., Mallard, C., Bernardi, P., Forte, M. A. & Hagberg, H., Feb 25 2009, In : Journal of Neuroscience. 29, 8, p. 2588-2596 9 p.

Research output: Contribution to journalArticle

96 Scopus citations

Direct actions of carbenoxolone on synaptic transmission and neuronal membrane properties

Tovar, K. R., Maher, B. J. & Westbrook, G. L., Aug 1 2009, In : Journal of neurophysiology. 102, 2, p. 974-978 5 p.

Research output: Contribution to journalArticle

86 Scopus citations

Drosophila neurexin IV stabilizes neuron-glia interactions at the CNS midline by binding to wrapper

Stork, T., Thomas, S., Rodrigues, F., Silies, M., Naffin, E., Wenderdel, S. & Klämbt, C., Apr 15 2009, In : Development. 136, 8, p. 1251-1261 11 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations

Ensheathing glia function as phagocytes in the adult Drosophila brain

Doherty, J., Logan, M. A., Taşdemir, Ö. E. & Freeman, M. R., Apr 15 2009, In : Journal of Neuroscience. 29, 15, p. 4768-4781 14 p.

Research output: Contribution to journalArticle

167 Scopus citations

ERK5 activity is required for nerve growth factor-induced neurite outgrowth and stabilization of tyrosine hydroxylase in PC12 cells

Obara, Y., Yamauchi, A., Takehara, S., Nemoto, W., Takahashi, M., Stork, P. J. S. & Nakahata, N., Aug 28 2009, In : Journal of Biological Chemistry. 284, 35, p. 23564-23573 10 p.

Research output: Contribution to journalArticle

50 Scopus citations

Experience-dependent maturation of the glomerular microcircuit

Maher, B. J., McGinley, M. J. & Westbrook, G. L., Sep 29 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 39, p. 16865-16870 6 p.

Research output: Contribution to journalArticle

43 Scopus citations

External tufted cells drive the output of olfactory bulb glomeruli

De Jan, D. S., Hirnet, D., Westbrook, G. L. & Charpak, S., Feb 18 2009, In : Journal of Neuroscience. 29, 7, p. 2043-2052 10 p.

Research output: Contribution to journalArticle

90 Scopus citations

Genetic ablation of cyclophilin D rescues mitochondrial defects and prevents muscle apoptosis in collagen VI myopathic mice

Palma, E., Tiepolo, T., Angelin, A., Sabatelli, P., Maraldi, N. M., Basso, E., Forte, M. A., Bernardip, P. & Bonaldo, P., May 19 2009, In : Human molecular genetics. 18, 11, p. 2024-2031 8 p.

Research output: Contribution to journalArticle

78 Scopus citations

Genetic deficit of SK3 and IK1 channels disrupts the endothelium-deerived hyperpolarizing factor vasodilator pathway and causes hypertension

Brähler, S., Kaistha, A., Schmidt, V. J., Wölfle, S. E., Busch, C., Kaistha, B. P., Kacik, M., Hasenau, A. L., Grgic, I., Si, H., Bond, C. T., Adelman, J. P., Wulff, H., De Wit, C., Hoyer, J. & Köhler, R., May 5 2009, In : Circulation. 119, 17, p. 2323-2332 10 p.

Research output: Contribution to journalArticle

173 Scopus citations

Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris

Fuentes-Medel, Y., Logan, M. A., Ashley, J., Ataman, B., Budnik, V. & Freeman, M. R., Aug 1 2009, In : PLoS Biology. 7, 8, e1000184.

Research output: Contribution to journalArticle

89 Scopus citations

GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis

Sano, R., Annunziata, I., Patterson, A., Moshiach, S., Gomero, E., Opferman, J., Forte, M. & d'Azzo, A., Nov 13 2009, In : Molecular Cell. 36, 3, p. 500-511 12 p.

Research output: Contribution to journalArticle

161 Scopus citations

Hemichannel-mediated and pH-based feedback from horizontal cells to cones in the vertebrate retina

Fahrenfort, I., Steijaert, M., Sjoerdsma, T., Vickers, E., Ripps, H., van Asselt, J., Endeman, D., Klooster, J., Numan, R., ten Eikelder, H., von Gersdorff, H. & Kamermans, M., Jun 30 2009, In : PloS one. 4, 6, e6090.

Research output: Contribution to journalArticle

54 Scopus citations

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

Tian, L., Hires, S. A., Mao, T., Huber, D., Chiappe, M. E., Chalasani, S. H., Petreanu, L., Akerboom, J., McKinney, S. A., Schreiter, E. R., Bargmann, C. I., Jayaraman, V., Svoboda, K. & Looger, L. L., Nov 9 2009, In : Nature Methods. 6, 12, p. 875-881 7 p.

Research output: Contribution to journalArticle

1211 Scopus citations

Myosin-dependent targeting of transmembrane proteins to neuronal dendrites

Lewis, T. L., Mao, T., Svoboda, K. & Arnold, D. B., May 1 2009, In : Nature Neuroscience. 12, 5, p. 568-576 9 p.

Research output: Contribution to journalArticle

129 Scopus citations

Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of μ-opioid receptors in CNS neurons

Yu, Y. J., Arttamangkul, S., Evans, C. J., Williams, J. T. & Von Zastrow, M., Jan 7 2009, In : Journal of Neuroscience. 29, 1, p. 222-233 12 p.

Research output: Contribution to journalArticle

53 Scopus citations

New sites of action for GIRK and SK channels

Luján, R., Maylie, J. & Adelman, J. P., Jul 1 2009, In : Nature Reviews Neuroscience. 10, 7, p. 475-480 6 p.

Research output: Contribution to journalArticle

76 Scopus citations

Non-cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology

Ballas, N., Lioy, D. T., Grunseich, C. & Mandel, G., Mar 1 2009, In : Nature Neuroscience. 12, 3, p. 311-317 7 p.

Research output: Contribution to journalArticle

302 Scopus citations

Photon capture and signalling by melanopsin retinal ganglion cells

Do, M. T. H., Kang, S. H., Xue, T., Zhong, H., Liao, H. W., Bergles, D. E. & Yau, K. W., Jan 15 2009, In : Nature. 457, 7227, p. 281-287 7 p.

Research output: Contribution to journalArticle

180 Scopus citations

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

Gonzales, E. B., Kawate, T. & Gouaux, E., Jul 30 2009, In : Nature. 460, 7255, p. 599-604 6 p.

Research output: Contribution to journalArticle

306 Scopus citations

Presynaptically expressed long-term potentiation increases multivesicular release at parallel fiber synapses

Bender, V. A., Pugh, J. R. & Jahr, C. E., Sep 2 2009, In : Journal of Neuroscience. 29, 35, p. 10974-10978 5 p.

Research output: Contribution to journalArticle

41 Scopus citations

Role of the synaptic ribbon in transmitting the cone light response

Jackman, S. L., Choi, S. Y., Thoreson, W. B., Rabl, K., Bartoletti, T. M. & Kramer, R. H., Mar 1 2009, In : Nature Neuroscience. 12, 3, p. 303-310 8 p.

Research output: Contribution to journalArticle

109 Scopus citations

Selective cognitive deficits and reduced hippocampal brain-derived neurotrophic factor mRNA expression in small-conductance calcium-activated K+ channel deficient mice

Jacobsen, J. P. R., Redrobe, J. P., Hansen, H. H., Petersen, S., Bond, C. T., Adelman, J. P., Mikkelsen, J. D. & Mirza, N. R., Sep 29 2009, In : Neuroscience. 163, 1, p. 73-81 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Selective expression of ligand-gated ion channels in L5 pyramidal cell axons

Christie, J. M. & Jahr, C. E., Sep 16 2009, In : Journal of Neuroscience. 29, 37, p. 11441-11450 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

SK2 channels are required for function and long-term survival of efferent synapses on mammalian outer hair cells

Murthy, V., Maison, S. F., Taranda, J., Haque, N., Bond, C. T., Elgoyhen, A. B., Adelman, J. P., Liberman, M. C. & Vetter, D. E., Jan 5 2009, In : Molecular and Cellular Neuroscience. 40, 1, p. 39-49 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Structure and mechanism of a Na+-independent amino acid transporter

Shaffer, P. L., Goehring, A., Shankaranarayanan, A. & Gouaux, E., Aug 31 2009, In : Science. 325, 5943, p. 1010-1014 5 p.

Research output: Contribution to journalArticle

222 Scopus citations

Subcellular Dynamics of Type II PKA in Neurons

Zhong, H., Sia, G. M., Sato, T. R., Gray, N. W., Mao, T., Khuchua, Z., Huganir, R. L. & Svoboda, K., May 14 2009, In : Neuron. 62, 3, p. 363-374 12 p.

Research output: Contribution to journalArticle

75 Scopus citations
Open Access
22 Scopus citations

The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex

Xiao, J. Y., Ruiz, G. V., Whorton, M. R., Rasmussen, S. G. F., DeVree, B. T., Deupi, X., Sunahara, R. K. & Kobilka, B., Jun 9 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 23, p. 9501-9506 6 p.

Research output: Contribution to journalArticle

163 Scopus citations
38 Scopus citations

The subcellular organization of neocortical excitatory connections

Petreanu, L., Mao, T., Sternson, S. M. & Svoboda, K., Feb 26 2009, In : Nature. 457, 7233, p. 1142-1145 4 p.

Research output: Contribution to journalArticle

541 Scopus citations

The time course of dopamine transmission in the ventral tegmental area

Ford, C. P., Phillips, P. E. M. & Williams, J. T., Oct 21 2009, In : Journal of Neuroscience. 29, 42, p. 13344-13352 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

The unitary event underlying multiquantal EPSCs at a hair cell's ribbon synapse

Li, G. L., Keen, E., Andor-Ardó, D., Hudspeth, A. J. & Von Gersdorff, H., Jun 10 2009, In : Journal of Neuroscience. 29, 23, p. 7558-7568 11 p.

Research output: Contribution to journalArticle

112 Scopus citations

Wld s requires Nmnatl enzymatic activity and N16- VCP interactions to suppress Wallerian degeneration

Avery, M. A., Sheehan, A. E., Kerr, K. S., Wang, J. & Freeman, M. R., Feb 23 2009, In : Journal of Cell Biology. 184, 4, p. 501-513 13 p.

Research output: Contribution to journalArticle

95 Scopus citations

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

Sobolevsky, A. I., Rosconi, M. P. & Gouaux, E., Dec 10 2009, In : Nature. 462, 7274, p. 745-756 12 p.

Research output: Contribution to journalArticle

711 Scopus citations
2008

A competitive inhibitor traps LeuT in an open-to-out conformation

Singh, S. K., Piscitelli, C. L., Yamashita, A. & Gouaux, E., Dec 12 2008, In : Science. 322, 5908, p. 1655-1661 7 p.

Research output: Contribution to journalArticle

314 Scopus citations

A genetically encoded fluorescent sensor of ERK activity

Harvey, C. D., Ehrhardt, A. G., Cellurale, C., Zhong, H., Yasuda, R., Davis, R. J. & Svoboda, K., Dec 9 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 49, p. 19264-19269 6 p.

Research output: Contribution to journalArticle

199 Scopus citations

A genome-wide screen for β-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression

Yochum, G. S., Cleland, R. & Goodman, R. H., Dec 1 2008, In : Molecular and cellular biology. 28, 24, p. 7368-7379 12 p.

Research output: Contribution to journalArticle

87 Scopus citations

Agonist-specific regulation of μ-opioid receptor desensitization and recovery from desensitization

Virk, M. S. & Williams, J. T., Apr 1 2008, In : Molecular pharmacology. 73, 4, p. 1301-1308 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP

Wayman, G. A., Davare, M., Ando, H., Fortin, D., Varlamova, O., Cheng, H. Y. M., Marks, D., Obrietan, K., Soderling, T. R., Goodman, R. H. & Impey, S., Jul 1 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 26, p. 9093-9098 6 p.

Research output: Contribution to journalArticle

422 Scopus citations

Cancer proliferation gene discovery through functional genomics

Schlabach, M. R., Luo, J., Solimini, N. L., Hu, G., Xu, Q., Li, M. Z., Zhao, Z., Smogorzewska, A., Sowa, M. E., Ang, X. L., Westbrook, T. F., Liang, A. C., Chang, K., Hackett, J. A., Harper, J. W., Hannon, G. J. & Elledge, S. J., Feb 1 2008, In : Science. 319, 5863, p. 620-624 5 p.

Research output: Contribution to journalArticle

308 Scopus citations

Characterization and subcellular targeting of GCaMP-type genetically-encoded calcium indicators

Mao, T., O'Connor, D. H., Scheuss, V., Nakai, J. & Svoboda, K., Mar 19 2008, In : PloS one. 3, 3, e1796.

Research output: Contribution to journalArticle

109 Scopus citations

Contextual memory deficits observed in mice overexpressing small conductance Ca2+-activated K+ type 2 (KCa2.2, SK2) channels are caused by an encoding deficit

Stackman, R. W., Bond, C. T. & Adelman, J. P., Apr 1 2008, In : Learning and Memory. 15, 4, p. 208-213 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Co-transmission of dopamine and GABA in periglomerular cells

Maher, B. J. & Westbrook, G. L., Mar 1 2008, In : Journal of neurophysiology. 99, 3, p. 1559-1564 6 p.

Research output: Contribution to journalArticle

60 Scopus citations

CRF Facilitates Calcium Release from Intracellular Stores in Midbrain Dopamine Neurons

Riegel, A. C. & Williams, J. T., Feb 28 2008, In : Neuron. 57, 4, p. 559-570 12 p.

Research output: Contribution to journalArticle

62 Scopus citations

Dendritic NMDA Receptors Activate Axonal Calcium Channels

Christie, J. M. & Jahr, C. E., Oct 23 2008, In : Neuron. 60, 2, p. 298-307 10 p.

Research output: Contribution to journalArticle

64 Scopus citations

Differential activation and trafficking of μ-opioid receptors in brain slices

Arttamangkul, S., Quillinan, N., Low, M. J., Von Zastrow, M., Pintar, J. & Williams, J. T., Oct 1 2008, In : Molecular pharmacology. 74, 4, p. 972-979 8 p.

Research output: Contribution to journalArticle

84 Scopus citations

Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase

Jin, J., Ang, X. L., Ye, X., Livingstone, M. & Harper, J. W., Jul 11 2008, In : Journal of Biological Chemistry. 283, 28, p. 19322-19328 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling

Ziegenfuss, J. S., Biswas, R., Avery, M. A., Hong, K., Sheehan, A. E., Yeung, Y. G., Stanley, E. R. & Freeman, M. R., Jun 12 2008, In : Nature. 453, 7197, p. 935-939 5 p.

Research output: Contribution to journalArticle

122 Scopus citations