Research Output 1987 2020

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2009
85 Citations (Scopus)

Direct actions of carbenoxolone on synaptic transmission and neuronal membrane properties

Tovar, K. R., Maher, B. J. & Westbrook, G., Aug 2009, In : Journal of Neurophysiology. 102, 2, p. 974-978 5 p.

Research output: Contribution to journalArticle

Carbenoxolone
Synaptic Transmission
Membranes
Excitatory Postsynaptic Potentials
Gap Junctions
48 Citations (Scopus)

ERK5 activity is required for nerve growth factor-induced neurite outgrowth and stabilization of tyrosine hydroxylase in PC12 cells

Obara, Y., Yamauchi, A., Takehara, S., Nemoto, W., Takahashi, M., Stork, P. & Nakahata, N., Aug 28 2009, In : Journal of Biological Chemistry. 284, 35, p. 23564-23573 10 p.

Research output: Contribution to journalArticle

PC12 Cells
Tyrosine 3-Monooxygenase
Nerve Growth Factor
Stabilization
Phosphorylation
43 Citations (Scopus)

Experience-dependent maturation of the glomerular microcircuit

Maher, B. J., McGinley, M. J. & Westbrook, G., Sep 29 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 39, p. 16865-16870 6 p.

Research output: Contribution to journalArticle

Gap Junctions
Dendrites
Sensory Deprivation
Membranes
Excitatory Postsynaptic Potentials
88 Citations (Scopus)

External tufted cells drive the output of olfactory bulb glomeruli

De Jan, D. S., Hirnet, D., Westbrook, G. & Charpak, S., Feb 18 2009, In : Journal of Neuroscience. 29, 7, p. 2043-2052 10 p.

Research output: Contribution to journalArticle

Olfactory Bulb
Olfactory Nerve
Population
Patch-Clamp Techniques
Transgenic Mice
75 Citations (Scopus)

Genetic ablation of cyclophilin D rescues mitochondrial defects and prevents muscle apoptosis in collagen VI myopathic mice

Palma, E., Tiepolo, T., Angelin, A., Sabatelli, P., Maraldi, N. M., Basso, E., Forte, M., Bernardip, P. & Bonaldo, P., 2009, In : Human Molecular Genetics. 18, 11, p. 2024-2031 8 p.

Research output: Contribution to journalArticle

Collagen
Permeability
Apoptosis
Muscles
Muscular Dystrophies
167 Citations (Scopus)

Genetic deficit of SK3 and IK1 channels disrupts the endothelium-deerived hyperpolarizing factor vasodilator pathway and causes hypertension

Brähler, S., Kaistha, A., Schmidt, V. J., Wölfle, S. E., Busch, C., Kaistha, B. P., Kacik, M., Hasenau, A. L., Grgic, I., Si, H., Bond, C. T., Adelman, J., Wulff, H., De Wit, C., Hoyer, J. & Köhler, R., May 5 2009, In : Circulation. 119, 17, p. 2323-2332 10 p.

Research output: Contribution to journalArticle

Vasodilator Agents
Endothelium
Hypertension
Blood Pressure
Vasodilation
150 Citations (Scopus)

GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis

Sano, R., Annunziata, I., Patterson, A., Moshiach, S., Gomero, E., Opferman, J., Forte, M. & d'Azzo, A., Nov 13 2009, In : Molecular Cell. 36, 3, p. 500-511 12 p.

Research output: Contribution to journalArticle

G(M1) Ganglioside
Mitochondria
Apoptosis
Membranes
Organelles
53 Citations (Scopus)

Hemichannel-mediated and pH-based feedback from horizontal cells to cones in the vertebrate retina

Fahrenfort, I., Steijaert, M., Sjoerdsma, T., Vickers, E., Ripps, H., van Asselt, J., Endeman, D., Klooster, J., Numan, R., ten Eikelder, H., Von Gersdorff, H. & Kamermans, M., Jun 30 2009, In : PLoS One. 4, 6, e6090.

Research output: Contribution to journalArticle

cones (retina)
retina
Vertebrates
Retina
Cones
52 Citations (Scopus)

Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of μ-opioid receptors in CNS neurons

Yu, Y. J., Arttamangkul, S., Evans, C. J., Williams, J. & Von Zastrow, M., Jan 7 2009, In : Journal of Neuroscience. 29, 1, p. 222-233 12 p.

Research output: Contribution to journalArticle

Neurokinin-1 Receptors
Opioid Receptors
Endocytosis
Morphine
Neurons
76 Citations (Scopus)

New sites of action for GIRK and SK channels

Luján, R., Maylie, J. & Adelman, J., Jul 2009, In : Nature Reviews Neuroscience. 10, 7, p. 475-480 6 p.

Research output: Contribution to journalArticle

Inwardly Rectifying Potassium Channel
GTP-Binding Proteins
Post-Synaptic Density
Dendritic Spines
Proteins
298 Citations (Scopus)

Non-cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology

Ballas, N., Lioy, D. T., Grunseich, C. & Mandel, G., Mar 2009, In : Nature Neuroscience. 12, 3, p. 311-317 7 p.

Research output: Contribution to journalArticle

Methyl-CpG-Binding Protein 2
Rett Syndrome
Neuroglia
Neurons
Astrocytes
297 Citations (Scopus)

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

Gonzales, E. B., Kawate, T. & Gouaux, E., Jul 30 2009, In : Nature. 460, 7255, p. 599-604 6 p.

Research output: Contribution to journalArticle

Acid Sensing Ion Channels
Ion Channels
Ions
FMRFamide
Epithelial Sodium Channels
40 Citations (Scopus)

Presynaptically expressed long-term potentiation increases multivesicular release at parallel fiber synapses

Bender, V. A., Pugh, J. R. & Jahr, C., Sep 2 2009, In : Journal of Neuroscience. 29, 35, p. 10974-10978 5 p.

Research output: Contribution to journalArticle

Long-Term Potentiation
Synapses
Interneurons
Presynaptic Receptors
Purinergic P1 Receptors
18 Citations (Scopus)

Selective cognitive deficits and reduced hippocampal brain-derived neurotrophic factor mRNA expression in small-conductance calcium-activated K+ channel deficient mice

Jacobsen, J. P. R., Redrobe, J. P., Hansen, H. H., Petersen, S., Bond, C. T., Adelman, J., Mikkelsen, J. D. & Mirza, N. R., Sep 29 2009, In : Neuroscience. 163, 1, p. 73-81 9 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Brain-Derived Neurotrophic Factor
Messenger RNA
Doxycycline
Parahippocampal Gyrus
36 Citations (Scopus)

Selective expression of ligand-gated ion channels in L5 pyramidal cell axons

Christie, J. M. & Jahr, C., Sep 16 2009, In : Journal of Neuroscience. 29, 37, p. 11441-11450 10 p.

Research output: Contribution to journalArticle

Ligand-Gated Ion Channels
Pyramidal Cells
N-Methyl-D-Aspartate Receptors
Axons
Visual Cortex
27 Citations (Scopus)

SK2 channels are required for function and long-term survival of efferent synapses on mammalian outer hair cells

Murthy, V., Maison, S. F., Taranda, J., Haque, N., Bond, C. T., Elgoyhen, A. B., Adelman, J., Liberman, M. C. & Vetter, D. E., Jan 5 2009, In : Molecular and Cellular Neuroscience. 40, 1, p. 39-49 11 p.

Research output: Contribution to journalArticle

Outer Auditory Hair Cells
Synapses
Auditory Hair Cells
Down-Regulation
Genes
216 Citations (Scopus)

Structure and mechanism of a Na+-independent amino acid transporter

Shaffer, P. L., Goehring, A., Shankaranarayanan, A. & Gouaux, E., 2009, In : Science. 325, 5943, p. 1010-1014 5 p.

Research output: Contribution to journalArticle

Amino Acid Transport Systems
Protons
Lysine
Amines
Sodium
22 Citations (Scopus)
Synaptic Vesicles
Exocytosis
Rats
Egtazic Acid
Buffers
38 Citations (Scopus)
Neurotransmitter Transport Proteins
neurotransmitters
Synapses
Neurotransmitter Agents
transporters
43 Citations (Scopus)

The time course of dopamine transmission in the ventral tegmental area

Ford, C. P., Phillips, P. E. M. & Williams, J., Oct 21 2009, In : Journal of Neuroscience. 29, 42, p. 13344-13352 9 p.

Research output: Contribution to journalArticle

Ventral Tegmental Area
Dopamine
G-Protein-Coupled Receptors
Mesencephalon
Potassium Channels
108 Citations (Scopus)

The unitary event underlying multiquantal EPSCs at a hair cell's ribbon synapse

Li, G. L., Keen, E., Andor-Ardó, D., Hudspeth, A. J. & Von Gersdorff, H., Jun 10 2009, In : Journal of Neuroscience. 29, 23, p. 7558-7568 11 p.

Research output: Contribution to journalArticle

Synapses
AMPA Receptors
Membranes
Synaptic Vesicles
Exocytosis
5 Citations (Scopus)

Traffic Jams during Vesicle Cycling Lead to Synaptic Depression

Kim, J. H. & Von Gersdorff, H., Jul 30 2009, In : Neuron. 63, 2, p. 143-145 3 p.

Research output: Contribution to journalArticle

Endocytosis
Synaptic Vesicles
Exocytosis
Catalytic Domain
Neurons
244 Citations (Scopus)

Unlocking the molecular secrets of sodium-coupled transporters

Krishnamurthy, H., Piscitelli, C. L. & Gouaux, E., May 21 2009, In : Nature. 459, 7245, p. 347-355 9 p.

Research output: Contribution to journalArticle

Sodium
Physiological Phenomena
Ions
Membranes
689 Citations (Scopus)

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

Sobolevsky, A. I., Rosconi, M. P. & Gouaux, E., Dec 10 2009, In : Nature. 462, 7274, p. 745-756 12 p.

Research output: Contribution to journalArticle

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Glutamate Receptors
Ion Channels
X-Rays
Ionotropic Glutamate Receptors
2008
304 Citations (Scopus)

A competitive inhibitor traps LeuT in an open-to-out conformation

Singh, S. K., Piscitelli, C. L., Yamashita, A. & Gouaux, E., Dec 12 2008, In : Science. 322, 5908, p. 1655-1661 7 p.

Research output: Contribution to journalArticle

tryptophan-leucine
Leucine
Plasma Membrane Neurotransmitter Transport Proteins
Ions
Aspartic Acid
85 Citations (Scopus)

A genome-wide screen for β-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression

Yochum, G. S., Cleland, R. & Goodman, R., Dec 2008, In : Molecular and Cellular Biology. 28, 24, p. 7368-7379 12 p.

Research output: Contribution to journalArticle

Catenins
myc Genes
Binding Sites
Genome
Gene Expression
40 Citations (Scopus)

Agonist-specific regulation of μ-opioid receptor desensitization and recovery from desensitization

Virk, M. S. & Williams, J., Apr 2008, In : Molecular Pharmacology. 73, 4, p. 1301-1308 8 p.

Research output: Contribution to journalArticle

Opioid Receptors
Opioid Analgesics
Oxycodone
Enkephalins
Oxymorphone
414 Citations (Scopus)

An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP

Wayman, G. A., Davare, M., Ando, H., Fortin, D., Varlamova, O., Cheng, H. Y. M., Marks, D., Obrietan, K., Soderling, T., Goodman, R. & Impey, S., Jul 1 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 26, p. 9093-9098 6 p.

Research output: Contribution to journalArticle

MicroRNAs
Dendrites
Cyclic AMP Response Element-Binding Protein
Gene Regulatory Networks
Growth
16 Citations (Scopus)

Contextual memory deficits observed in mice overexpressing small conductance Ca2+-activated K+ type 2 (KCa2.2, SK2) channels are caused by an encoding deficit

Stackman, R. W., Bond, C. T. & Adelman, J., Apr 2008, In : Learning and Memory. 15, 4, p. 208-213 6 p.

Research output: Contribution to journalArticle

Memory Disorders
Neuronal Plasticity
Apamin
Calcium-Activated Potassium Channels
Transgenic Mice
227 Citations (Scopus)

Control of KCa Channels by Calcium Nano/Microdomains

Fakler, B. & Adelman, J., Sep 25 2008, In : Neuron. 59, 6, p. 873-881 9 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Cell Physiological Phenomena
Calcium Channels
Ions
Neurons
56 Citations (Scopus)

Co-transmission of dopamine and GABA in periglomerular cells

Maher, B. J. & Westbrook, G., Mar 2008, In : Journal of Neurophysiology. 99, 3, p. 1559-1564 6 p.

Research output: Contribution to journalArticle

gamma-Aminobutyric Acid
Dopamine
Olfactory Receptor Neurons
Tyrosine
Excitatory Postsynaptic Potentials
62 Citations (Scopus)

CRF Facilitates Calcium Release from Intracellular Stores in Midbrain Dopamine Neurons

Riegel, A. C. & Williams, J., Feb 28 2008, In : Neuron. 57, 4, p. 559-570 12 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Corticotropin-Releasing Hormone
Mesencephalon
Calcium
Neuronal Plasticity
64 Citations (Scopus)

Dendritic NMDA Receptors Activate Axonal Calcium Channels

Christie, J. M. & Jahr, C., Oct 23 2008, In : Neuron. 60, 2, p. 298-307 10 p.

Research output: Contribution to journalArticle

Calcium Channels
N-Methyl-D-Aspartate Receptors
Axons
Monovalent Cations
Interneurons
82 Citations (Scopus)

Differential activation and trafficking of μ-opioid receptors in brain slices

Arttamangkul, S., Quillinan, N., Low, M. J., Von Zastrow, M., Pintar, J. & Williams, J., Oct 2008, In : Molecular Pharmacology. 74, 4, p. 972-979 8 p.

Research output: Contribution to journalArticle

Opioid Receptors
Enkephalins
Brain
Neurons
Epitopes
38 Citations (Scopus)

Enhancement of anxiety, facilitation of avoidance behavior, and occurrence of adult-onset obesity in mice lacking mitochondrial cyclophilin D

Luvisetto, S., Basso, E., Petronilli, V., Bernardi, P. & Forte, M., Aug 26 2008, In : Neuroscience. 155, 3, p. 585-596 12 p.

Research output: Contribution to journalArticle

Avoidance Learning
Anxiety
Obesity
White Adipose Tissue
cyclophilin D
28 Citations (Scopus)

Expression of the SK2 calcium-activated potassium channel is required for cholinergic function in mouse cochlear hair cells

Kong, J. H., Adelman, J. & Fuchs, P. A., Nov 15 2008, In : Journal of Physiology. 586, 22, p. 5471-5485 15 p.

Research output: Contribution to journalArticle

Auditory Hair Cells
Calcium-Activated Potassium Channels
Cholinergic Receptors
Outer Auditory Hair Cells
Inner Auditory Hair Cells
69 Citations (Scopus)

Functional roles of a Ca2+ -activated K+ channel in atrioventricular nodes

Zhang, Q., Timofeyev, V., Lu, L., Li, N., Singapuri, A., Long, M. K., Bond, C. T., Adelman, J. & Chiamvimonvat, N., Feb 2008, In : Circulation Research. 102, 4, p. 465-471 7 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Atrioventricular Node
Ion Channels
Action Potentials
Cardiac Arrhythmias
17 Citations (Scopus)

Function of neuromuscular synapses in the zebrafish choline- acetyltransferase mutant bajan

Wang, M., Wen, H. & Brehm, P., Oct 2008, In : Journal of Neurophysiology. 100, 4, p. 1995-2004 10 p.

Research output: Contribution to journalArticle

Choline O-Acetyltransferase
Zebrafish
Synapses
Fatigue
Acetylcholine
16 Citations (Scopus)

Heterogeneous Ca2+ influx along the adult calyx of held: A structural and computational study

Spirou, G. A., Chirila, F. V., Von Gersdorff, H. & Manis, P. B., Jun 12 2008, In : Neuroscience. 154, 1, p. 171-185 15 p.

Research output: Contribution to journalArticle

Action Potentials
Ion Channels
Evoked Potentials
Synapses
Axons
179 Citations (Scopus)

Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels

Chiara, F., Castellaro, D., Marin, O., Petronilli, V., Brusilow, W. S., Juhaszova, M., Sollott, S. J., Forte, M., Bernardi, P. & Rasola, A., Mar 19 2008, In : PLoS One. 3, 3, e1852.

Research output: Contribution to journalArticle

Voltage-Dependent Anion Channels
Mitochondria
Hexokinase
hexokinase
anions
4 Citations (Scopus)

Mesoprefrontal Dopamine Neurons Distinguish Themselves

Ford, C. P. & Williams, J., Mar 13 2008, In : Neuron. 57, 5, p. 631-632 2 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Ventral Tegmental Area
Dopamine
Neurons
30 Citations (Scopus)

Morphine produces circuit-specific neuroplasticity in the bed nucleus of the stria terminalis

Dumont, É. C., Rycroft, B. K., Maiz, J. & Williams, J., Apr 22 2008, In : Neuroscience. 153, 1, p. 232-239 8 p.

Research output: Contribution to journalArticle

Septal Nuclei
Neuronal Plasticity
Morphine
Neurons
Ventral Tegmental Area
51 Citations (Scopus)

Neurotransmitter Modulation of Small-Conductance Ca2+-Activated K+ Channels by Regulation of Ca2+ Gating

Maingret, F., Coste, B., Hao, J., Giamarchi, A., Allen, D., Crest, M., Litchfield, D. W., Adelman, J. & Delmas, P., Aug 14 2008, In : Neuron. 59, 3, p. 439-449 11 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Calmodulin
Neurotransmitter Agents
Casein Kinase II
Protein Phosphatase 2
74 Citations (Scopus)

Neurotrophin-dependent dendritic filopodial motility: A convergence on PI3K signaling

Luikart, B. W., Zhang, W., Wayman, G. A., Kwon, C. H., Westbrook, G. & Parada, L. F., Jul 2 2008, In : Journal of Neuroscience. 28, 27, p. 7006-7012 7 p.

Research output: Contribution to journalArticle

Pseudopodia
1-Phosphatidylinositol 4-Kinase
Nerve Growth Factors
Receptor Protein-Tyrosine Kinases
Brain-Derived Neurotrophic Factor
124 Citations (Scopus)

Phosphate is essential for inhibition of the mitochondrial permeability transition pore by cyclosporin A and by cyclophilin D ablation

Basso, E., Petronilli, V., Forte, M. & Bernardi, P., Sep 26 2008, In : Journal of Biological Chemistry. 283, 39, p. 26307-26311 5 p.

Research output: Contribution to journalArticle

Ablation
Cyclosporine
Vanadates
Permeability
Phosphates
20 Citations (Scopus)

Pre- and postsynaptic regulation of locus coeruleus neurons after chronic morphine treatment: A study of GIRK-knockout mice

Torrecilla, M., Quillinan, N., Williams, J. & Wickman, K., Aug 2008, In : European Journal of Neuroscience. 28, 3, p. 618-624 7 p.

Research output: Contribution to journalArticle

Locus Coeruleus
Knockout Mice
Morphine
Neurons
Opioid Analgesics
15 Citations (Scopus)

Protein kinase C modulates synaptic vesicle acidification in a ribbon type nerve terminal in the retina

Abreu, B. J., Guimarães, M., Uliana, L. C., Vigh, J., Von Gersdorff, H., Prado, M. A. & Guatimosim, C., Nov 2008, In : Neurochemistry International. 53, 5, p. 155-164 10 p.

Research output: Contribution to journalArticle

Synaptic Vesicles
Protein Kinase C
Retina
Fluorescence
Retinal Bipolar Cells
41 Citations (Scopus)

Ras is required for the cyclic AMP-dependent activation of Rap1 via Epac2

Liu, C., Takahashi, M., Li, Y., Song, S., Dillon, T. J., Shinde, U. & Stork, P., Dec 2008, In : Molecular and Cellular Biology. 28, 23, p. 7109-7125 17 p.

Research output: Contribution to journalArticle

Cyclic AMP
Guanine Nucleotide Exchange Factors
Monomeric GTP-Binding Proteins
PC12 Cells
Exocytosis
35 Citations (Scopus)

Release of the styryl dyes from single synaptic vesicles in hippocampal neurons

Chen, X., Barg, S. & Almers, W., Feb 20 2008, In : Journal of Neuroscience. 28, 8, p. 1894-1903 10 p.

Research output: Contribution to journalArticle

Synaptic Vesicles
Coloring Agents
Exocytosis
Neurons
Signal-To-Noise Ratio
141 Citations (Scopus)

SK2 channel plasticity contributes to LTP at Schaffer collateral-CA1 synapses

Lin, M. T., Luján, R., Watanabe, M., Adelman, J. & Maylie, J., Feb 2008, In : Nature Neuroscience. 11, 2, p. 170-177 8 p.

Research output: Contribution to journalArticle

Long-Term Potentiation
Synapses
Hippocampus
AMPA Receptors
Excitatory Postsynaptic Potentials