Research Output 1987 2020

Filter
Article
2011
27 Citations (Scopus)

Ovarian hormone deficiency reduces intrinsic excitability and abolishes acute estrogen sensitivity in hippocampal CA1 pyramidal neurons

Wu, W., Adelman, J. & Maylie, J., Feb 16 2011, In : Journal of Neuroscience. 31, 7, p. 2638-2648 11 p.

Research output: Contribution to journalArticle

Pyramidal Cells
Estrogens
Hormones
Membranes
Action Potentials
666 Citations (Scopus)

Principles of activation and permeation in an anion-selective Cys-loop receptor

Hibbs, R. E. & Gouaux, E., Jun 2 2011, In : Nature. 474, 7349, p. 54-60 7 p.

Research output: Contribution to journalArticle

Cysteine Loop Ligand-Gated Ion Channel Receptors
Anions
Ivermectin
Picrotoxin
Synaptic Transmission
44 Citations (Scopus)

Properties of Ca 2+ transport in mitochondria of Drosophila melanogaster

Von Stockum, S., Basso, E., Petronilli, V., Sabatelli, P., Forte, M. & Bernardi, P., Dec 2 2011, In : Journal of Biological Chemistry. 286, 48, p. 41163-41170 8 p.

Research output: Contribution to journalArticle

Mitochondria
Drosophila melanogaster
Mammals
Permeability
Ruthenium Red
88 Citations (Scopus)

Pten knockdown in vivo increases excitatory drive onto dentate granule cells

Luikart, B. W., Schnell, E., Washburn, E. K., Bensen, A. L., Tovar, K. R. & Westbrook, G., Mar 16 2011, In : Journal of Neuroscience. 31, 11, p. 4345-4354 10 p.

Research output: Contribution to journalArticle

Dendritic Spines
Phosphoric Monoester Hydrolases
Young Adult
Hippocampus
Chromosomes, Human, Pair 10
5 Citations (Scopus)

Reconstitution of interactions of Murine gammaherpesvirus 68 M11 with Bcl-2 family proteins in yeast

Juhásová, B., Bhatia-Kiššová, I., Polčicová, K., Mentel, M., Forte, M. & Polčic, P., Apr 22 2011, In : Biochemical and Biophysical Research Communications. 407, 4, p. 783-787 5 p.

Research output: Contribution to journalArticle

Fungal Proteins
Yeast
Apoptosis
BH3 Interacting Domain Death Agonist Protein
bcl-2 Homologous Antagonist-Killer Protein
59 Citations (Scopus)

Recovery from short-term depression and facilitation is ultrafast and ca dependent at auditory hair cell synapses

Cho, S., Li, G. L. & Von Gersdorff, H., Apr 13 2011, In : Journal of Neuroscience. 31, 15, p. 5682-5692 11 p.

Research output: Contribution to journalArticle

Auditory Hair Cells
Synapses
Membrane Potentials
Synaptic Vesicles
Egtazic Acid
54 Citations (Scopus)

Recovery from μ-opioid receptor desensitization after chronic treatment with morphine and methadone

Quillinan, N., Lau, E. K., Virk, M., Von Zastrow, M. & Williams, J., Mar 23 2011, In : Journal of Neuroscience. 31, 12, p. 4434-4443 10 p.

Research output: Contribution to journalArticle

Methadone
Opioid Receptors
Morphine
Arrestin
Opioid Analgesics
38 Citations (Scopus)

Repressor element 1 silencing transcription factor (REST) controls radial migration and temporal neuronal specification during neocortical development

Mandel, G., Fiondella, C. G., Covey, M. V., Lu, D. D., LoTurco, J. J. & Ballas, N., Oct 4 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 40, p. 16789-16794 6 p.

Research output: Contribution to journalArticle

Transcriptional Silencer Elements
Transcription Factors
Neurogenesis
Classical Lissencephalies and Subcortical Band Heterotopias
Phenotype
94 Citations (Scopus)

Sharp Ca 2+ Nanodomains beneath the ribbon promote highly synchronous multivesicular release at hair cell synapses

Graydon, C. W., Cho, S., Li, G. L., Kachar, B. & Von Gersdorff, H., Nov 16 2011, In : Journal of Neuroscience. 31, 46, p. 16637-16650 14 p.

Research output: Contribution to journalArticle

Synapses
Buffers
Synaptic Vesicles
Rana catesbeiana
Egtazic Acid
47 Citations (Scopus)

SK2 channels are neuroprotective for ischemia-induced neuronal cell death

Allen, D., Nakayama, S., Kuroiwa, M., Nakano, T., Palmateer, J., Kosaka, Y., Ballesteros, C., Watanabe, M., Bond, C. T., Luján, R., Maylie, J., Adelman, J. & Herson, P. S., Dec 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 12, p. 2302-2312 11 p.

Research output: Contribution to journalArticle

Cardiopulmonary Resuscitation
Cell Death
Ischemia
Heart Arrest
N-Methyl-D-Aspartate Receptors
103 Citations (Scopus)

The Ca v3.3 calcium channel is the major sleep spindle pacemaker in thalamus

Astori, S., Wimmer, R. D., Prosser, H. M., Corti, C., Corsi, M., Liaudet, N., Volterra, A., Franken, P., Adelman, J. & Lüthi, A., Aug 16 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 33, p. 13823-13828 6 p.

Research output: Contribution to journalArticle

Calcium Channels
Thalamus
Sleep
Electroencephalography
Eye Movements
36 Citations (Scopus)

The SK2-long isoform directs synaptic localization and function of SK2-containing channels

Allen, D., Bond, C. T., Lujàn, R., Ballesteros-Merino, C., Lin, M. T., Wang, K., Klett, N., Watanabe, M., Shigemoto, R., Stackman Jr, R. W., Maylie, J. & Adelman, J., Jun 2011, In : Nature Neuroscience. 14, 6, p. 744-749 6 p.

Research output: Contribution to journalArticle

Protein Isoforms
Post-Synaptic Density
Neuronal Plasticity
Pyramidal Cells
Learning
2010
19 Citations (Scopus)
Locus Coeruleus
Potassium Channels
Methadone
Opioid Receptors
N-Methylaspartate
43 Citations (Scopus)

Affinity purification of microRNA-133a with the cardiac transcription factor, Hand2

Vo, N., Dalton, R. P., Liu, N., Olson, E. N. & Goodman, R., Nov 9 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 45, p. 19231-19236 6 p.

Research output: Contribution to journalArticle

MicroRNAs
Transcription Factors
Messenger RNA
3' Untranslated Regions
Computational Biology
202 Citations (Scopus)

An activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signaling

Impey, S., Davare, M., Lasiek, A., Fortin, D., Ando, H., Varlamova, O., Obrietan, K., Soderling, T., Goodman, R. & Wayman, G. A., Jan 2010, In : Molecular and Cellular Neuroscience. 43, 1, p. 146-156 11 p.

Research output: Contribution to journalArticle

Dendritic Spines
MicroRNAs
Spine
Neuronal Plasticity
Gene Regulatory Networks
52 Citations (Scopus)

A β-catenin/TCF-coordinated chromatin loop at MYC integrates 5′ and 3′ Wnt responsive enhancers

Yochum, G. S., Sherrick, C. M., MacPartlin, M. & Goodman, R., 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 1, p. 145-150 6 p.

Research output: Contribution to journalArticle

Catenins
Chromatin
Mitogens
Gene Expression
Wnt Signaling Pathway
9 Citations (Scopus)

Cholinergic Signaling through Synaptic SK Channels: It's a Protein Kinase but Which One?

Maylie, J. & Adelman, J., Dec 9 2010, In : Neuron. 68, 5, p. 809-811 3 p.

Research output: Contribution to journalArticle

Protein Kinases
Cholinergic Agents
Neurons
Cognition
78 Citations (Scopus)

Control of extracellular dopamine at dendrite and axon terminals

Ford, C. P., Gantz, S. C., Phillips, P. E. M. & Williams, J., May 19 2010, In : Journal of Neuroscience. 30, 20, p. 6975-6983 9 p.

Research output: Contribution to journalArticle

Presynaptic Terminals
Dendrites
Dopamine
Ventral Tegmental Area
Dextrans
23 Citations (Scopus)

Coupled activity-dependent trafficking of synaptic SK2 channels and AMPA receptors

Lin, M. T., Luján, R., Watanabe, M., Frerking, M., Maylie, J. & Adelman, J., Sep 1 2010, In : Journal of Neuroscience. 30, 35, p. 11726-11734 9 p.

Research output: Contribution to journalArticle

AMPA Receptors
Long-Term Potentiation
Endocytosis
Exocytosis
Spine
110 Citations (Scopus)

Cyclophilin D in mitochondrial pathophysiology

Giorgio, V., Soriano, M. E., Basso, E., Bisetto, E., Lippe, G., Forte, M. & Bernardi, P., Jun 2010, In : Biochimica et Biophysica Acta - Bioenergetics. 1797, 6-7, p. 1113-1118 6 p.

Research output: Contribution to journalArticle

Cyclophilins
Mitochondrial Proton-Translocating ATPases
Peptidylprolyl Isomerase
Mitochondria
Cell death
59 Citations (Scopus)

Developmental shift to a mechanism of synaptic vesicle endocytosis requiring nanodomain Ca2+

Yamashita, T., Eguchi, K., Saitoh, N., Von Gersdorff, H. & Takahashi, T., Jul 2010, In : Nature Neuroscience. 13, 7, p. 838-844 7 p.

Research output: Contribution to journalArticle

Synaptic Vesicles
Endocytosis
Synapses
Exocytosis
Calcineurin
67 Citations (Scopus)

Distinct roles for two synaptotagmin isoforms in synchronous and asynchronous transmitter release at zebrafish neuromuscular junction

Wen, H., Linhoff, M. W., McGinley, M. J., Li, G. L., Corson, G. M., Mandel, G. & Brehm, P., Aug 3 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 31, p. 13906-13911 6 p.

Research output: Contribution to journalArticle

Synaptotagmins
Neuromuscular Junction
Zebrafish
Protein Isoforms
Synaptotagmin II
210 Citations (Scopus)

Dynamic superresolution imaging of endogenous proteins on living cells at ultra-high density

Giannone, G., Hosy, E., Levet, F., Constals, A., Schulze, K., Sobolevsky, A. I., Rosconi, M. P., Gouaux, E., Tampe, R., Choquet, D. & Cognet, L., Aug 9 2010, In : Biophysical Journal. 99, 4, p. 1303-1310 8 p.

Research output: Contribution to journalArticle

Proteins
Membrane Proteins
Membranes
Biological Science Disciplines
Synapses
60 Citations (Scopus)

Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model

Larsson, H. P., Wang, X., Lev, B., Baconguis, I., Caplan, D. A., Vyleta, N. P., Koch, H. P., Diez-Sampedro, A. & Noskov, S. Y., Aug 3 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 31, p. 13912-13917 6 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
Sodium
Binding Sites
Glutamic Acid
Ions
3 Citations (Scopus)

Extending the realm of membrane capacitance measurements to nerve terminals with complex morphologies

Kim, M. H. & Von Gersdorff, H., Jun 2010, In : Journal of Physiology. 588, 12, p. 2011-2012 2 p.

Research output: Contribution to journalArticle

Electric Capacitance
Ion Channel Gating
Neurological Models
Miniature Postsynaptic Potentials
Retinal Rod Photoreceptor Cells
59 Citations (Scopus)

Inputs to the dorsal striatum of the mouse reflect the parallel circuit architecture of the forebrain

Pan, W. X., Mao, T. & Dudman, J. T., Dec 27 2010, In : Frontiers in Neuroanatomy. DEC

Research output: Contribution to journalArticle

Prosencephalon
Basal Ganglia
Corpus Striatum
Raphe Nuclei
Amygdala
279 Citations (Scopus)

MicroRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus

Magill, S. T., Cambronne, X., Luikart, B. W., Lioy, D. T., Leighton, B. H., Westbrook, G., Mandel, G. & Goodman, R., Nov 23 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 47, p. 20382-20387 6 p.

Research output: Contribution to journalArticle

Neuronal Plasticity
Cyclic AMP Response Element-Binding Protein
MicroRNAs
Hippocampus
Neurons
59 Citations (Scopus)

MicroRNA pathways in neural development and plasticity

Vo, N., Cambronne, X. & Goodman, R., Aug 2010, In : Current Opinion in Neurobiology. 20, 4, p. 457-465 9 p.

Research output: Contribution to journalArticle

Neuronal Plasticity
MicroRNAs
Neurons
Aptitude
RNA Stability
74 Citations (Scopus)

Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores

Banerjee, A., Mikhailova, E., Cheley, S., Gu, L. Q., Montoya, M., Nagaoka, Y., Gouaux, E. & Bayley, H., May 4 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 18, p. 8165-8170 6 p.

Research output: Contribution to journalArticle

Nanopores
Protein Engineering
Porins
Crystallography
Hemolysin Proteins
98 Citations (Scopus)

Neurotransmitter/sodium symporter orthologue LeuT has a single high-affinity substrate site

Piscitelli, C. L., Krishnamurthy, H. & Gouaux, E., Dec 23 2010, In : Nature. 468, 7327, p. 1129-1133 5 p.

Research output: Contribution to journalArticle

Plasma Membrane Neurotransmitter Transport Proteins
Binding Sites
Sodium
Neurotransmitter Agents
Calorimetry
11 Citations (Scopus)

Opioid receptor internalization contributes to dermorphin-mediated antinociception

Macey, T. A., Ingram, S., Bobeck, E. N., Hegarty, D. M., Aicher, S., Arttamangkul, S. & Morgan, M. M., Jun 2010, In : Neuroscience. 168, 2, p. 543-550 8 p.

Research output: Contribution to journalArticle

Periaqueductal Gray
Microinjections
Opioid Receptors
Dynamins
mu Opioid Receptor
11 Citations (Scopus)
Clamping devices
Motor Neurons
Zebrafish
Neurons
Muscle
4 Citations (Scopus)

Post-tetanic potentiation involves the presynaptic binding of calcium to calmodulin

Balakrishnan, V., Srinivasan, G. & Von Gersdorff, H., Sep 2010, In : Journal of General Physiology. 136, 3, p. 243-245 3 p.

Research output: Contribution to journalArticle

Myosin Type II
Myosin-Light-Chain Kinase
Neuronal Plasticity
Synaptic Vesicles
Excitatory Postsynaptic Potentials
49 Citations (Scopus)

Presynaptic resurgent Na+ currents sculpt the action potential waveform and increase firing reliability at a CNS nerve terminal

Kim, J. H., Kushmerick, C. & Von Gersdorff, H., Nov 17 2010, In : Journal of Neuroscience. 30, 46, p. 15479-15490 12 p.

Research output: Contribution to journalArticle

Action Potentials
Dialysis
Peptide Fragments
Presynaptic Terminals
Lidocaine
95 Citations (Scopus)

Sensing muscle ischemia: Coincident detection of acid and ATP via interplay of two ion channels

Birdsong, W. T., Fierro, L., Williams, F. G., Spelta, V., Naves, L. A., Knowles, M., Marsh-Haffner, J., Adelman, J., Almers, W., Elde, R. P. & McCleskey, E. W., Nov 18 2010, In : Neuron. 68, 4, p. 739-749 11 p.

Research output: Contribution to journalArticle

Adenine Nucleotides
Ion Channels
Ischemia
Sensory Receptor Cells
Pain
65 Citations (Scopus)

Single secretory granules of live cells recruit syntaxin-1 and synaptosomal associated protein 25 (SNAP-25) in large copy numbers

Knowles, M. K., Barg, S., Wan, L., Midorikawa, M., Chen, X. & Almers, W., Nov 30 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 48, p. 20810-20815 6 p.

Research output: Contribution to journalArticle

Synaptosomal-Associated Protein 25
Syntaxin 1
Secretory Vesicles
Fluorescence
Exocytosis
70 Citations (Scopus)

Syntaxin clusters assemble reversibly at sites of secretory granules in live cells

Barg, S., Knowles, M. K., Chen, X., Midorikawa, M. & Almers, W., Nov 30 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 48, p. 20804-20809 6 p.

Research output: Contribution to journalArticle

Qa-SNARE Proteins
Secretory Vesicles
Exocytosis
Cell Membrane
SNARE Proteins
33 Citations (Scopus)

The interaction of Epac1 and ran promotes Rap1 activation at the nuclear envelope

Liu, C., Takahashi, M., Li, Y., Dillon, T. J., Kaech-Petrie, S. & Stork, P., Aug 2010, In : Molecular and Cellular Biology. 30, 16, p. 3956-3969 14 p.

Research output: Contribution to journalArticle

Nuclear Envelope
Cyclic AMP
Nuclear Pore
Monomeric GTP-Binding Proteins
ras Proteins
90 Citations (Scopus)

The mitochondrial permeability transition from yeast to mammals

Azzolin, L., von Stockum, S., Basso, E., Petronilli, V., Forte, M. & Bernardi, P., Jun 2010, In : FEBS Letters. 584, 12, p. 2504-2509 6 p.

Research output: Contribution to journalArticle

Mammals
Yeast
Permeability
Mitochondria
Yeasts
35 Citations (Scopus)

The New York Consortium on Membrane Protein Structure (NYCOMPS): A high-throughput platform for structural genomics of integral membrane proteins

Love, J., Mancia, F., Shapiro, L., Punta, M., Rost, B., Girvin, M., Wang, D. N., Zhou, M., Hunt, J. F., Szyperski, T., Gouaux, E., MacKinnon, R., McDermott, A., Honig, B., Inouye, M., Montelione, G. & Hendrickson, W. A., Sep 2010, In : Journal of Structural and Functional Genomics. 11, 3, p. 191-199 9 p.

Research output: Contribution to journalArticle

Genomics
Membrane Proteins
Throughput
Pipelines
Crystallography
2009
123 Citations (Scopus)

Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation

Li, N., Timofeyev, V., Tuteja, D., Xu, D., Lu, L., Zhang, Q., Zhang, Z., Singapuri, A., Albert, T. R., Rajagopal, A. V., Bond, C. T., Periasamy, M., Adelman, J. & Chiamvimonvat, N., 2009, In : Journal of Physiology. 587, 5, p. 1087-1100 14 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Muscle Cells
Action Potentials
Cardiac Arrhythmias
Wild Animals
101 Citations (Scopus)

Axonal degeneration in multiple sclerosis: The mitochondrial hypothesis

Su, K. G., Banker, G., Bourdette, D. & Forte, M., 2009, In : Current Neurology and Neuroscience Reports. 9, 5, p. 411-417 7 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Axonal Transport
Demyelinating Diseases
Free Radicals
Permeability
30 Citations (Scopus)

Buprenorphine is a weak partial agonist that inhibits opioid receptor desensitization

Virk, M. S., Arttamangkul, S., Birdsong, W. T. & Williams, J., Jun 3 2009, In : Journal of Neuroscience. 29, 22, p. 7341-7348 8 p.

Research output: Contribution to journalArticle

Buprenorphine
Opioid Receptors
Oxymorphone
Etorphine
Locus Coeruleus
51 Citations (Scopus)

Ca2+ signaling by T-type Ca2+ channels in neurons

Cueni, L., Canepari, M., Adelman, J. & Lüthi, A., Mar 2009, In : Pflugers Archiv European Journal of Physiology. 457, 5, p. 1161-1172 12 p.

Research output: Contribution to journalArticle

Neurons
Electric potential
Chemical activation
42 Citations (Scopus)

CRF enhancement of GIRK channel-mediated transmission in dopamine neurons

Beckstead, M. J., Gantz, S. C., Ford, C. P., Stenzel-Poore, M., Phillips, P. E. M., Mark, G. & Williams, J., Jul 2009, In : Neuropsychopharmacology. 34, 8, p. 1926-1935 10 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Corticotropin-Releasing Hormone
Dopamine
Inhibitory Postsynaptic Potentials
Mesencephalon
121 Citations (Scopus)

Crystal structure and association behaviour of the GluR2 amino-terminal domain

Jin, R., Singh, S. K., Gu, S., Furukawa, H., Sobolevsky, A. I., Zhou, J., Jin, Y. & Gouaux, E., Jun 17 2009, In : EMBO Journal. 28, 12, p. 1812-1823 12 p.

Research output: Contribution to journalArticle

AMPA Receptors
Crystal structure
Ligand-Gated Ion Channels
Ionotropic Glutamate Receptors
Kainic Acid Receptors
485 Citations (Scopus)

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

Kawate, T., Michel, J. C., Birdsong, W. T. & Gouaux, E., Jul 30 2009, In : Nature. 460, 7255, p. 592-598 7 p.

Research output: Contribution to journalArticle

Ion Channels
Adenosine Triphosphate
Cations
Ion Channel Gating
Physiological Phenomena
3 Citations (Scopus)

Crystal structures of catalytic and regulatory subunits of rat protein kinase CK2

Zhou, W. H., Qin, X. H., Yan, X. J., Xie, X. Q., Li, L., Fang, S. S., Long, J. F., Adelman, J., Tang, W. J. & Shen, Y. Q., Jan 2009, In : Chinese Science Bulletin. 54, 2, p. 220-226 7 p.

Research output: Contribution to journalArticle

Casein Kinase II
Conformations
Rats
Crystal structure
Plasticity
176 Citations (Scopus)

Cyclophilin D modulates mitochondrial F0F1-ATP synthase by interacting with the lateral stalk of the complex

Giorgio, V., Bisetto, E., Soriano, M. E., Dabbeni-Sala, F., Basso, E., Petronilli, V., Forte, M., Bernardi, P. & Lippe, G., Dec 4 2009, In : Journal of Biological Chemistry. 284, 49, p. 33982-33988 7 p.

Research output: Contribution to journalArticle

Mitochondrial Proton-Translocating ATPases
Adenosine Triphosphate
Mitochondria
Enzyme activity
Enzymes
93 Citations (Scopus)

Developmental shift of cyclophilin D contribution to hypoxic-ischemic brain injury

Wang, X., Carlsson, Y., Basso, E., Zhu, C., Rousset, C. I., Rasola, A., Johansson, B. R., Blomgren, K., Mallard, C., Bernardi, P., Forte, M. & Hagberg, H., Feb 25 2009, In : Journal of Neuroscience. 29, 8, p. 2588-2596 9 p.

Research output: Contribution to journalArticle

Brain Injuries
Cell Death
Brain
Caspases
Permeability