Research Output

Filter
Article
2012

Combining Comparative Proteomics and Molecular Genetics Uncovers Regulators of Synaptic and Axonal Stability and Degeneration In Vivo

Wishart, T. M., Rooney, T. M., Lamont, D. J., Wright, A. K., Morton, A. J., Jackson, M., Freeman, M. R. & Gillingwater, T. H., Aug 2012, In : PLoS genetics. 8, 8, e1002936.

Research output: Contribution to journalArticle

37 Scopus citations

Connexin 39.9 protein is necessary for coordinated activation of slow-twitch muscle and normal behavior in zebrafish

Hirata, H., Wen, H., Kawakami, Y., Naganawa, Y., Ogino, K., Yamada, K., Saint-Amant, L., Low, S. E., Cui, W. W., Zhou, W., Sprague, S. M., Asakawa, K., Muto, A., Kawakami, K. & Kuwada, J. Y., Jan 6 2012, In : Journal of Biological Chemistry. 287, 2, p. 1080-1089 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Desensitization and trafficking of μ-opioid receptors in locus ceruleus neurons: Modulation by kinases

Arttamangkul, S., Lau, E. K., Lu, H. W. & Williams, J. T., Mar 2012, In : Molecular pharmacology. 81, 3, p. 348-355 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Developmental profile of SK2 channel expression and function in CA1 neurons

Ballesteros-Merino, C., Lin, M., Wu, W. W., Ferrandiz-Huertas, C., Cabañero, M. J., Watanabe, M., Fukazawa, Y., Shigemoto, R., Maylie, J., Adelman, J. P. & Luján, R., Jun 2012, In : Hippocampus. 22, 6, p. 1467-1480 14 p.

Research output: Contribution to journalArticle

25 Scopus citations

Dissecting signaling and functions of adhesion G protein-coupled receptors

Araç, D., Aust, G., Calebiro, D., Engel, F. B., Formstone, C., Goffinet, A., Hamann, J., Kittel, R. J., Liebscher, I., Lin, H. H., Monk, K. R., Petrenko, A., Piao, X., Prömel, S., Schiöth, H. B., Schwartz, T. W., Stacey, M., Ushkaryov, Y. A., Wobus, M., Wolfrum, U. & 2 others, Xu, L. & Langenhan, T., Dec 2012, In : Annals of the New York Academy of Sciences. 1276, 1, p. 1-25 25 p.

Research output: Contribution to journalArticle

28 Scopus citations

Distinct molecular pathways mediate glial activation and engulfment of axonal debris after axotomy

Ziegenfuss, J. S., Doherty, J. & Freeman, M. R., Jul 2012, In : Nature Neuroscience. 15, 7, p. 979-987 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

dSarm/Sarm1 is required for activation of an injury-induced axon death pathway

Osterloh, J. M., Yang, J., Rooney, T. M., Fox, A. N., Adalbert, R., Powell, E. H., Sheehan, A. E., Avery, M. A., Hackett, R., Logan, M. A., MacDonald, J. M., Ziegenfuss, J. S., Milde, S., Hou, Y. J., Nathan, C., Ding, A., Brown, R. H., Conforti, L., Coleman, M., Tessier-Lavigne, M. & 2 others, Züchner, S. & Freeman, M. R., Jul 27 2012, In : Science. 337, 6093, p. 481-484 4 p.

Research output: Contribution to journalArticle

265 Scopus citations

Dystroglycan Organizes Axon Guidance Cue Localization and Axonal Pathfinding

Wright, K. M., Lyon, K. A., Leung, H., Leahy, D. J., Ma, L. & Ginty, D. D., Dec 6 2012, In : Neuron. 76, 5, p. 931-944 14 p.

Research output: Contribution to journalArticle

101 Scopus citations
13 Scopus citations

Gdnf Activates Midline Repulsion by Semaphorin3B via NCAM during Commissural Axon Guidance

Charoy, C., Nawabi, H., Reynaud, F., Derrington, E., Bozon, M., Wright, K., Falk, J., Helmbacher, F., Kindbeiter, K. & Castellani, V., Sep 20 2012, In : Neuron. 75, 6, p. 1051-1066 16 p.

Research output: Contribution to journalArticle

66 Scopus citations
14 Scopus citations

Genetic inactivation of the p66 isoform of ShcA is neuroprotective in a murine model of multiple sclerosis

Su, K. G., Savino, C., Marracci, G., Chaudhary, P., Yu, X., Morris, B., Galipeau, D., Giorgio, M., Forte, M. & Bourdette, D., Feb 2012, In : European Journal of Neuroscience. 35, 3-4, p. 562-571 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

GPER1/GPR30 Activation Improves Neuronal Survival Following Global Cerebral Ischemia Induced by Cardiac Arrest in Mice

Kosaka, Y., Quillinan, N., Bond, C. T., Traystman, R. J., Hurn, P. D. & Herson, P. S., Dec 2012, In : Translational Stroke Research. 3, 4, p. 500-507 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Increasing SK2 channel activity impairs associative learning

McKay, B. M., Matthew Oh, M., Galvez, R., Burgdorf, J., Kroes, R. A., Weiss, C., Adelman, J. P., Moskal, J. R. & Disterhoft, J. F., Aug 1 2012, In : Journal of neurophysiology. 108, 3, p. 863-870 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Insights into transport mechanism from LeuT engineered to transport tryptophan

Piscitelli, C. L. & Gouaux, E., Jan 4 2012, In : EMBO Journal. 31, 1, p. 228-235 8 p.

Research output: Contribution to journalArticle

37 Scopus citations

Integration of a retrograde signal during synapse formation by glia-secreted TGF-β ligand

Fuentes-Medel, Y., Ashley, J., Barria, R., Maloney, R., Freeman, M. & Budnik, V., Oct 9 2012, In : Current Biology. 22, 19, p. 1831-1838 8 p.

Research output: Contribution to journalArticle

68 Scopus citations

MeCP2 is critical for maintaining mature neuronal networks and global brain anatomy during late stages of postnatal brain development and in the mature adult brain

Nguyen, M. V. C., Du, F., Felice, C. A., Shan, X., Nigam, A., Mandel, G., Robinson, J. K. & Ballas, N., Jul 18 2012, In : Journal of Neuroscience. 32, 29, p. 10021-10034 14 p.

Research output: Contribution to journalArticle

113 Scopus citations
17 Scopus citations

Modulation of endothelial SK3 channel activity by Ca2+-dependent caveolar trafficking

Lin, M. T., Adelman, J. P. & Maylie, J., Aug 1 2012, In : American Journal of Physiology - Cell Physiology. 303, 3, p. 318-327 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Molecular mechanism of ATP binding and ion channel activation in P2X receptors

Hattori, M. & Gouaux, E., May 9 2012, In : Nature. 485, 7397, p. 207-212 6 p.

Research output: Contribution to journalArticle

318 Scopus citations

Morphine desensitization and cellular tolerance are distinguished in rat locus ceruleus neurons

Levitt, E. S. & Williams, J. T., Nov 2012, In : Molecular pharmacology. 82, 5, p. 983-992 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Negative regulation of glial engulfment activity by Draper terminates glial responses to axon injury

Logan, M. A., Hackett, R., Doherty, J., Sheehan, A., Speese, S. D. & Freeman, M. R., May 2012, In : Nature Neuroscience. 15, 5, p. 722-730 9 p.

Research output: Contribution to journalArticle

46 Scopus citations

Neuroligin-1 Overexpression in Newborn Granule Cells In Vivo

Schnell, E., Bensen, A. S. L., Washburn, E. K. & Westbrook, G. L., Oct 22 2012, In : PloS one. 7, 10, e48045.

Research output: Contribution to journalArticle

14 Scopus citations

Pain-facilitating medullary neurons contribute to opioid-induced respiratory depression

Phillips, R. S., Cleary, D. R., Nalwalk, J. W., Arttamangkul, S., Hough, L. B. & Heinricher, M. M., Nov 1 2012, In : Journal of neurophysiology. 108, 9, p. 2393-2404 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

Paired-pulse plasticity in the strength and latency of light-evoked lateral inhibition to retinal bipolar cell terminals

Vickers, E., Kim, M. H., Vigh, J. & von Gersdorff, H., Aug 22 2012, In : Journal of Neuroscience. 32, 34, p. 11688-11699 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Paradoxical contribution of SK3 and GIRK channels to the activation of mouse vomeronasal organ

Kim, S., Ma, L., Jensen, K. L., Kim, M. M., Bond, C. T., Adelman, J. P. & Yu, C. R., Sep 2012, In : Nature Neuroscience. 15, 9, p. 1236-1244 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Patch-clamp capacitance measurements and Ca2+ imaging at single nerve terminals in retinal slices

Kim, M. H., Vickers, E. & von Gersdorff, H., 2012, In : Journal of Visualized Experiments. 59, p. 1-6 6 p., e3345.

Research output: Contribution to journalArticle

5 Scopus citations

Preparation of an awake mouse for recording neural responses and injecting tracers

Muniak, M. A., Mayko, Z. M., Ryugo, D. K. & Portfors, C. V., Jun 26 2012, In : Journal of Visualized Experiments. 64, p. 1 1 p., e3755.

Research output: Contribution to journalArticle

19 Scopus citations

Regulation of microRNA-375 by cAMP in pancreatic-βcells

Keller, D. M., Clark, E. A. & Goodman, R. H., Jun 2012, In : Molecular Endocrinology. 26, 6, p. 989-999 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

Regulation of presynaptic strength by controlling Ca 2+ channel mobility: Effects of cholesterol depletion on release at the cone ribbon synapse

Mercer, A. J., Szalewski, R. J., Jackman, S. L., Van Hook, M. J. & Thoreson, W. B., Jun 15 2012, In : Journal of neurophysiology. 107, 12, p. 3468-3478 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Short-term field stimulation mimics synaptic maturation of hippocampal synapses

Bagley, E. E. & Westbrook, G. L., Apr 2012, In : Journal of Physiology. 590, 7, p. 1641-1654 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

SK2 and SK3 expression differentially affect firing frequency and precision in dopamine neurons

Deignan, J., Luján, R., Bond, C., Riegel, A., Watanabe, M., Williams, J. T., Maylie, J. & Adelman, J. P., Aug 16 2012, In : Neuroscience. 217, p. 67-76 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

SK2 channel modulation contributes to compartment-specific dendritic plasticity in cerebellar Purkinje cells

Ohtsuki, G., Piochon, C., Adelman, J. P. & Hansel, C., Jul 12 2012, In : Neuron. 75, 1, p. 108-120 13 p.

Research output: Contribution to journalArticle

55 Scopus citations

Small-conductance Ca 2+-activated K + channels: Form and function

Adelman, J. P., Maylie, J. & Sah, P., 2012, In : Annual Review of Physiology. 74, p. 245-269 25 p.

Research output: Contribution to journalArticle

261 Scopus citations

Structural plasticity and dynamic selectivity of acid-sensing ion channelspider toxin complexes

Baconguis, I. & Gouaux, E., Sep 20 2012, In : Nature. 489, 7416, p. 400-405 6 p.

Research output: Contribution to journalArticle

174 Scopus citations

Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context

Wang, H., Elferich, J. & Gouaux, E., Feb 2012, In : Nature Structural and Molecular Biology. 19, 2, p. 212-219 8 p.

Research output: Contribution to journalArticle

80 Scopus citations

Substrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue

Wang, H. & Gouaux, E., Sep 2012, In : EMBO Reports. 13, 9, p. 861-866 6 p.

Research output: Contribution to journalArticle

31 Scopus citations
22 Scopus citations

Sustaining sleep spindles through enhanced SK2-channel activity consolidates sleep and elevates arousal threshold

Wimmer, R. D., Astori, S., Bond, C. T., Rovó, Z., Chatton, J. Y., Adelman, J. P., Franken, P. & Lüthi, A., Oct 3 2012, In : Journal of Neuroscience. 32, 40, p. 13917-13928 12 p.

Research output: Contribution to journalArticle

35 Scopus citations

Thyroid hormone drives fetal cardiomyocyte maturation

Chattergoon, N. N., Giraud, G. D., Louey, S., Stork, P., Fowden, A. L. & Thornburg, K. L., Jan 2012, In : FASEB Journal. 26, 1, p. 397-408 12 p.

Research output: Contribution to journalArticle

85 Scopus citations

Whole genome sequencing and a new bioinformatics platform allow for rapid gene identification in d. melanogaster EMS screens

Gonzalez, M. A., VanBooven, D., Hulme, W., Ulloa, R. H., Lebrigio, R. F. A., Osterloh, J., Logan, M., Freeman, M. & Zuchner, S., Dec 5 2012, In : Biology. 1, 3, p. 766-777 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Wld S prevents axon degeneration through increased mitochondrial flux and enhanced mitochondrial Ca 2+ buffering

Avery, M. A., Rooney, T. M., Pandya, J. D., Wishart, T. M., Gillingwater, T. H., Geddes, J. W., Sullivan, P. G. & Freeman, M. R., Apr 10 2012, In : Current Biology. 22, 7, p. 596-600 5 p.

Research output: Contribution to journalArticle

97 Scopus citations

X-ray structures of LeuT in substrate-free outward-open and apo inward-open states

Krishnamurthy, H. & Gouaux, E., Jan 26 2012, In : Nature. 481, 7382, p. 469-474 6 p.

Research output: Contribution to journalArticle

331 Scopus citations

Zebrafish model for congenital myasthenic syndrome reveals mechanisms causal to developmental recovery

Walogorsky, M., Mongeon, R., Wen, H., Nelson, N. R., Urban, J. M., Ono, F., Mandel, G. & Brehm, P., Oct 23 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 43, p. 17711-17716 6 p.

Research output: Contribution to journalArticle

10 Scopus citations
2011

Activation of the mitochondrial permeability transition pore modulates Ca2+ responses to physiological stimuli in adult neurons

Barsukova, A., Komarov, A., Hajnóczky, G., Bernardi, P., Bourdette, D. & Forte, M., Mar 2011, In : European Journal of Neuroscience. 33, 5, p. 831-842 12 p.

Research output: Contribution to journalArticle

59 Scopus citations

Allosteric modulation of retinal GABA receptors by ascorbic acid

Calero, C. I., Vickers, E., Cid, G. M., Aguayo, L. G., von Gersdorff, H. & Calvo, D. J., Jun 29 2011, In : Journal of Neuroscience. 31, 26, p. 9672-9682 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Amino terminal domains of the NMDA receptor are organized as local heterodimers

Lee, C. H. & Gouaux, E., 2011, In : PloS one. 6, 4, e19180.

Research output: Contribution to journalArticle

29 Scopus citations

An acetylcholine receptor lacking both γ and ε subunits mediates transmission in zebrafish slow muscle synapses

Mongeon, R., Walogorsky, M., Urban, J., Mandel, G., Ono, F. & Brehm, P., Sep 2011, In : Journal of General Physiology. 138, 3, p. 353-366 14 p.

Research output: Contribution to journalArticle

14 Scopus citations

A positive feedback synapse from retinal horizontal cells to cone photoreceptors

Jackman, S. L., Babai, N., Chambers, J. J., Thoreson, W. B. & Kramer, R. H., May 2011, In : PLoS Biology. 9, 5, e1001057.

Research output: Contribution to journalArticle

44 Scopus citations

A role for glia in the progression of Rett-syndrome

Lioy, D. T., Garg, S. K., Monaghan, C. E., Raber, J., Foust, K. D., Kaspar, B. K., Hirrlinger, P. G., Kirchhoff, F., Bissonnette, J. M., Ballas, N. & Mandel, G., Jul 28 2011, In : Nature. 475, 7357, p. 497-500 4 p.

Research output: Contribution to journalArticle

313 Scopus citations