Research Output 1987 2019

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9 Citations (Scopus)

Cocaine and amphetamine interact at 5-HT synapses through distinct mechanisms in guinea-pig prepositus hypoglossi

Bobker, D. H. & Williams, J., 1991, In : Journal of Neuroscience. 11, 7, p. 2151-2156 6 p.

Research output: Contribution to journalArticle

Inhibitory Postsynaptic Potentials
Amphetamine
Cocaine
Synapses
Serotonin
9 Citations (Scopus)

Cocaine Decreases Metabotropic Glutamate Receptor mGluR1 Currents in Dopamine Neurons by Activating mGluR5

Kramer, P. F. & Williams, J., Apr 1 2015, In : Neuropsychopharmacology. 40, 10, p. 2418-2424 7 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate Receptors
Dopaminergic Neurons
Cocaine
Injections
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
1 Citation (Scopus)

Cocaine-induced adaptation of dopamine D2S, but not D2L autoreceptors

Robinson, B. G., Condon, A. F., Radl, D., Borrelli, E., Williams, J. & Neve, K., Nov 20 2017, In : eLife. 6, e31924.

Research output: Contribution to journalArticle

Autoreceptors
Cocaine
Neurons
Plasticity
Dopamine
13 Citations (Scopus)

Cocaine induced synchronous oscillations in central noradrenergic neurons In vitro

Harris, G. C., Hausken, Z. E. & Williams, J., 1992, In : Neuroscience. 50, 2, p. 253-257 5 p.

Research output: Contribution to journalArticle

Adrenergic Neurons
Cocaine
Neurons
Adrenergic Antagonists
Locus Coeruleus
158 Citations (Scopus)

Cocaine inhibits GABA release in the VTA through endogenous 5-HT

Cameron, D. L. & Williams, J., 1994, In : Journal of Neuroscience. 14, 11 I, p. 6763-6767 5 p.

Research output: Contribution to journalArticle

Ventral Tegmental Area
Cocaine
gamma-Aminobutyric Acid
Serotonin
Dopaminergic Neurons
5 Citations (Scopus)

Cocaine prolongs norepinephrine synaptic potentials in rat dorsal raphe

Oleskevich, S. & Williams, J., 1995, In : Journal of Neurophysiology. 73, 2, p. 687-692 6 p.

Research output: Contribution to journalArticle

Synaptic Potentials
Excitatory Postsynaptic Potentials
Cocaine
Norepinephrine
Adrenergic Receptors
22 Citations (Scopus)

Cocaine self-administration selectively decreases noradrenergic regulation of metabotropic glutamate receptor-mediated inhibition in dopamine neurons

Paladini, C. A., Mitchell, J. M., Williams, J. & Mark, G., Jun 2 2004, In : Journal of Neuroscience. 24, 22, p. 5209-5215 7 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate Receptors
Self Administration
Dopaminergic Neurons
Cocaine
Drug-Seeking Behavior
31 Citations (Scopus)
Gonadotropin-Releasing Hormone
In Situ Hybridization
Immunohistochemistry
RNA
Brain
16 Citations (Scopus)

Commentary: SPG7 is an essential and conserved component of the mitochondrial permeability transition pore

Bernardi, P. & Forte, M., 2015, In : Frontiers in Physiology. 6, NOV, 320.

Research output: Contribution to journalArticle

Mitochondria
Cell Death
mitochondrial permeability transition pore
14 Citations (Scopus)

Comparative phosphoproteomics reveals components of host cell invasion and post-transcriptional regulation during francisella infection

Nakayasu, E. S., Tempel, R., Cambronne, X., Petyuk, V. A., Jones, M. B., Gritsenko, M. A., Monroe, M. E., Yang, F., Smith, R. D., Adkins, J. N. & Heffron, F., Nov 2013, In : Molecular and Cellular Proteomics. 12, 11, p. 3297-3309 13 p.

Research output: Contribution to journalArticle

Francisella
Tristetraprolin
Cellular Structures
Phosphorylation
Cell death
138 Citations (Scopus)

Comparison of coupled and uncoupled currents during glutamate uptake by GLT-1 transporters

Bergles, D. E., Tzingounis, A. V. & Jahr, C., Dec 1 2002, In : Journal of Neuroscience. 22, 23, p. 10153-10162 10 p.

Research output: Contribution to journalArticle

Anions
Glutamic Acid
Amino Acid Transport System X-AG
Extracellular Space
Cations
121 Citations (Scopus)

Connexin36 mediates spike synchrony in olfactory bulb glomeruli

Christie, J. M., Bark, C., Hormuzdi, S. G., Helbig, I., Monyer, H. & Westbrook, G., Jun 2 2005, In : Neuron. 46, 5, p. 761-772 12 p.

Research output: Contribution to journalArticle

Olfactory Bulb
Gap Junctions
Dendrites
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Connexins
6 Citations (Scopus)

Connexin 39.9 protein is necessary for coordinated activation of slow-twitch muscle and normal behavior in zebrafish

Hirata, H., Wen, H., Kawakami, Y., Naganawa, Y., Ogino, K., Yamada, K., Saint-Amant, L., Low, S. E., Cui, W. W., Zhou, W., Sprague, S. M., Asakawa, K., Muto, A., Kawakami, K. & Kuwada, J. Y., Jan 6 2012, In : Journal of Biological Chemistry. 287, 2, p. 1080-1089 10 p.

Research output: Contribution to journalArticle

Connexins
Zebrafish
Muscle
Gap Junctions
Chemical activation
52 Citations (Scopus)

Consensus and Variant cAMP-regulated Enhancers Have Distinct CREB-binding Properties

Craig, J. C., Schumacher, M. A., Mansoor, S. E., Farrens, D., Brennan, R. G. & Goodman, R., Apr 13 2001, In : Journal of Biological Chemistry. 276, 15, p. 11719-11728 10 p.

Research output: Contribution to journalArticle

Cyclic AMP Response Element-Binding Protein
Protein Binding
Dimerization
DNA
Ions
57 Citations (Scopus)

Construction of a 1.2-Mb contig surrounding, and molecular analysis of, the human CREB-binding protein (CBP/CREBBP) gene on chromosome 16p13.3

Giles, R. H., Petrij, F., Dauwerse, H. G., Den Hollander, A. I., Lushnikova, T., Van Ommen, G. J. B., Goodman, R., Deaven, L. L., Doggett, N. A., Peters, D. J. M. & Breuning, M. H., May 15 1997, In : Genomics. 42, 1, p. 96-114 19 p.

Research output: Contribution to journalArticle

Cosmids
Rubinstein-Taybi Syndrome
Chromosomes
Genes
Acute Myeloid Leukemia
15 Citations (Scopus)

Contextual memory deficits observed in mice overexpressing small conductance Ca2+-activated K+ type 2 (KCa2.2, SK2) channels are caused by an encoding deficit

Stackman, R. W., Bond, C. T. & Adelman, J., Apr 2008, In : Learning and Memory. 15, 4, p. 208-213 6 p.

Research output: Contribution to journalArticle

Memory Disorders
Neuronal Plasticity
Apamin
Calcium-Activated Potassium Channels
Transgenic Mice
35 Citations (Scopus)

Contributions of the C-terminal domain to gating properties of inward rectifier potassium channels

Pessia, M., Bond, C. T., Kavanaugh, M. P. & Adelman, J., 1995, In : Neuron. 14, 5, p. 1039-1045 7 p.

Research output: Contribution to journalArticle

Inwardly Rectifying Potassium Channel
GTP-Binding Proteins
Potassium Channels
Signal Transduction
300 Citations (Scopus)

Control of cAMP-regulated enhancers by the viral transactivator tax through CREB and the co-activator CBP

Kwok, R. P. S., Laurance, M. E., Lundblad, J., Goldman, P. S., Shih, H. M., Connor, L. M., Marriott, S. J. & Goodman, R., 1996, In : Nature. 380, 6575, p. 642-646 5 p.

Research output: Contribution to journalArticle

Trans-Activators
Cyclic AMP
tax Gene Products
Phosphorylation
Terminal Repeat Sequences
179 Citations (Scopus)

Control of Electrical Activity in Central Neurons by Modulating the Gating of Small Conductance Ca2+-activated K+ Channels

Pedarzani, P., Mosbacher, J., Rivard, A., Cingolani, L. A., Oliver, D., Stocker, M., Adelman, J. & Fakler, B., Mar 30 2001, In : Journal of Biological Chemistry. 276, 13, p. 9762-9769 8 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Neurons
Calmodulin
Small-Conductance Calcium-Activated Potassium Channels
Neurology
77 Citations (Scopus)

Control of extracellular dopamine at dendrite and axon terminals

Ford, C. P., Gantz, S. C., Phillips, P. E. M. & Williams, J., May 19 2010, In : Journal of Neuroscience. 30, 20, p. 6975-6983 9 p.

Research output: Contribution to journalArticle

Presynaptic Terminals
Dendrites
Dopamine
Ventral Tegmental Area
Dextrans
224 Citations (Scopus)

Control of KCa Channels by Calcium Nano/Microdomains

Fakler, B. & Adelman, J., Sep 25 2008, In : Neuron. 59, 6, p. 873-881 9 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Cell Physiological Phenomena
Calcium Channels
Ions
Neurons
46 Citations (Scopus)

Cooperative interactions among subunits of a voltage-dependent potassium channel: Evidence from expression of concatenated cDNAs

Hurst, R. S., Kavanaugh, M. P., Yakel, J., Adelman, J. & North, R. A., Nov 25 1992, In : Journal of Biological Chemistry. 267, 33, p. 23742-23745 4 p.

Research output: Contribution to journalArticle

Tetraethylammonium
Potassium Channels
Amino Acid Substitution
Complementary DNA
RNA
9 Citations (Scopus)
Cyclic AMP Response Element Modulator
Cyclic AMP Response Element-Binding Protein
Phosphoenolpyruvate
CCAAT-Enhancer-Binding Proteins
Protein Binding
91 Citations (Scopus)

Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A

Xu, J., Bauer, D. E., Kerenyi, M. A., Vo, T. D., Hou, S., Hsu, Y. J., Yao, H., Trowbridge, J. J., Mandel, G. & Orkin, S. H., Apr 16 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 16, p. 6518-6523 6 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Co-Repressor Proteins
Globins
Erythroid Cells
Methyltransferases
15 Citations (Scopus)

Corepressor Rcor1 is essential for murine erythropoiesis

Yao, H., Goldman, D., Nechiporuk, T., Kawane, S., McWeeney, S., Tyner, J., Fan, G., Kerenyi, M. A., Orkin, S. H., Fleming, W. & Mandel, G., May 15 2014, In : Blood. 123, 20, p. 3175-3184 10 p.

Research output: Contribution to journalArticle

Co-Repressor Proteins
Erythropoiesis
Genes
Erythroblasts
Colony-Stimulating Factor Receptors
2 Citations (Scopus)

Corrigendum to "An activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signaling" [YMCNE (2010) 146-156]

Impey, S., Davare, M., Lesiak, A., Fortin, D., Ando, H., Varlamova, O., Obrietan, K., Soderling, T., Goodman, R. & Wayman, G. A., Feb 2012, In : Molecular and Cellular Neuroscience. 49, 2, p. 250 1 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Co-transmission of dopamine and GABA in periglomerular cells

Maher, B. J. & Westbrook, G., Mar 2008, In : Journal of Neurophysiology. 99, 3, p. 1559-1564 6 p.

Research output: Contribution to journalArticle

gamma-Aminobutyric Acid
Dopamine
Olfactory Receptor Neurons
Tyrosine
Excitatory Postsynaptic Potentials
22 Citations (Scopus)

Coupled activity-dependent trafficking of synaptic SK2 channels and AMPA receptors

Lin, M. T., Luján, R., Watanabe, M., Frerking, M., Maylie, J. & Adelman, J., Sep 1 2010, In : Journal of Neuroscience. 30, 35, p. 11726-11734 9 p.

Research output: Contribution to journalArticle

AMPA Receptors
Long-Term Potentiation
Endocytosis
Exocytosis
Spine
322 Citations (Scopus)

Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter

Boudker, O., Ryan, R. M., Yernool, D., Shimamoto, K. & Gouaux, E., Jan 25 2007, In : Nature. 445, 7126, p. 387-393 7 p.

Research output: Contribution to journalArticle

Aspartic Acid
Sodium
Ions
Binding Sites
Lipid Bilayers
621 Citations (Scopus)

CREB-binding Protein and p300 in Transcriptional Regulation

Vo, N. & Goodman, R., Apr 27 2001, In : Journal of Biological Chemistry. 276, 17, p. 13505-13508 4 p.

Research output: Contribution to journalArticle

Genetic Transcription
CREB-Binding Protein
Biological Models
Trans-Activators
Interferon-beta
55 Citations (Scopus)
Cyclic AMP Response Element-Binding Protein
Calcium-Calmodulin-Dependent Protein Kinases
Neuronal Plasticity
Depolarization
Response Elements
41 Citations (Scopus)

CRF enhancement of GIRK channel-mediated transmission in dopamine neurons

Beckstead, M. J., Gantz, S. C., Ford, C. P., Stenzel-Poore, M., Phillips, P. E. M., Mark, G. & Williams, J., Jul 2009, In : Neuropsychopharmacology. 34, 8, p. 1926-1935 10 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Corticotropin-Releasing Hormone
Dopamine
Inhibitory Postsynaptic Potentials
Mesencephalon
62 Citations (Scopus)

CRF Facilitates Calcium Release from Intracellular Stores in Midbrain Dopamine Neurons

Riegel, A. C. & Williams, J., Feb 28 2008, In : Neuron. 57, 4, p. 559-570 12 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Corticotropin-Releasing Hormone
Mesencephalon
Calcium
Neuronal Plasticity
35 Citations (Scopus)

Critical roles of a small conductance Ca2+-activated K + channel (SK3) in the repolarization process of atrial myocytes

Zhang, X. D., Timofeyev, V., Li, N., Myers, R. E., Zhang, D. M., Singapuri, A., Lau, V. C., Bond, C. T., Adelman, J., Lieu, D. K. & Chiamvimonvat, N., Feb 2014, In : Cardiovascular Research. 101, 2, p. 317-325 9 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Muscle Cells
Action Potentials
pamidronate
Cardiac Myocytes
679 Citations (Scopus)

Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation

Stork, P. & Schmitt, J. M., Jun 1 2002, In : Trends in Cell Biology. 12, 6, p. 258-266 9 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinases
Cyclic AMP
Cell Proliferation
Growth
GTP Phosphohydrolases
62 Citations (Scopus)

Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating

Martin, G. M., Yoshioka, C., Rex, E. A., Fay, J. F., Xie, Q., Whorton, M., Chen, J. Z. & Shyng, S-L., Jan 16 2017, In : eLife. 6, e24149.

Research output: Contribution to journalArticle

KATP Channels
Glyburide
Adenosine Triphosphate
Hypoglycemic Agents
Conformations
22 Citations (Scopus)

Cryo-EM structure of the benzodiazepine-sensitive α1β1γ2S tri-heteromeric GABAA receptor in complex with GABA

Phulera, S., Zhu, H., Yu, J., Claxton, D. P., Yoder, N., Yoshioka, C. & Gouaux, E., Jul 25 2018, In : eLife. 7, e39383.

Research output: Contribution to journalArticle

GABA-A Receptors
Benzodiazepines
gamma-Aminobutyric Acid
Ion Channels
Cysteine Loop Ligand-Gated Ion Channel Receptors
43 Citations (Scopus)

Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation

Lü, W., Du, J., Goehring, A. & Gouaux, E., Mar 24 2017, In : Science. 355, 6331, eaal3729.

Research output: Contribution to journalArticle

N-Methyl-D-Aspartate Receptors
Ion Channel Gating
Ion Channels
Electron Microscopy
121 Citations (Scopus)

Crystal structure and association behaviour of the GluR2 amino-terminal domain

Jin, R., Singh, S. K., Gu, S., Furukawa, H., Sobolevsky, A. I., Zhou, J., Jin, Y. & Gouaux, E., Jun 17 2009, In : EMBO Journal. 28, 12, p. 1812-1823 12 p.

Research output: Contribution to journalArticle

AMPA Receptors
Crystal structure
Ligand-Gated Ion Channels
Ionotropic Glutamate Receptors
Kainic Acid Receptors
479 Citations (Scopus)

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

Kawate, T., Michel, J. C., Birdsong, W. T. & Gouaux, E., Jul 30 2009, In : Nature. 460, 7255, p. 592-598 7 p.

Research output: Contribution to journalArticle

Ion Channels
Adenosine Triphosphate
Cations
Ion Channel Gating
Physiological Phenomena
3 Citations (Scopus)

Crystal structures of catalytic and regulatory subunits of rat protein kinase CK2

Zhou, W. H., Qin, X. H., Yan, X. J., Xie, X. Q., Li, L., Fang, S. S., Long, J. F., Adelman, J., Tang, W. J. & Shen, Y. Q., Jan 2009, In : Chinese Science Bulletin. 54, 2, p. 220-226 7 p.

Research output: Contribution to journalArticle

Casein Kinase II
Conformations
Rats
Crystal structure
Plasticity
140 Citations (Scopus)

C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs

Grooteclaes, M., Deveraux, Q., Hildebrand, J., Zhang, Q., Goodman, R. & Frisch, S. M., Apr 15 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 8, p. 4568-4573 6 p.

Research output: Contribution to journalArticle

Gene Expression
Epithelial-Mesenchymal Transition
Apoptosis
Genes
Co-Repressor Proteins
23 Citations (Scopus)

C-terminal domain small phosphatase 1 and MAP kinase reciprocally control REST stability and neuronal differentiation

Nesti, E., Corson, G. M., McCleskey, M., Oyer, J. A. & Mandel, G., Sep 16 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 37, p. E3929-E3936

Research output: Contribution to journalArticle

Phosphoric Monoester Hydrolases
Stem Cells
Neurogenesis
Phosphorylation
cis-trans-Isomerases
25 Citations (Scopus)

Cubitus interruptus requires Drosophila CREB-binding protein to activate wingless expression in the Drosophila embryo

Chen, Y., Goodman, R. & Smolik, S. M., Mar 2000, In : Molecular and Cellular Biology. 20, 5, p. 1616-1625 10 p.

Research output: Contribution to journalArticle

CREB-Binding Protein
Drosophila Proteins
Transcriptional Activation
Drosophila
Hedgehogs
46 Citations (Scopus)

Current inactivation involves a histidine residue in the pore of the rat lymphocyte potassium channel RGK5

Busch, A. E., Hurst, R. S., North, R. A., Adelman, J. & Kavanaugh, M. P., Sep 30 1991, In : Biochemical and Biophysical Research Communications. 179, 3, p. 1384-1390 7 p.

Research output: Contribution to journalArticle

Lymphocytes
Potassium Channels
Histidine
Tyrosine
Rats
14 Citations (Scopus)

Cyclic 3,5 adenoise monophosphate and cyclosporin A inhibit cellular proliferation and serine/threonine protein phosphatase activity in pituitary cells

Florio, T., Perrino, B. A. & Stork, P., 1996, In : Endocrinology. 137, 10, p. 4409-4418 10 p.

Research output: Contribution to journalArticle

Phosphoprotein Phosphatases
Protein Phosphatase 1
Cyclosporine
Cell Proliferation
Calcium
55 Citations (Scopus)

Cyclic adenosine monophosphate can convert epidermal growth factor into a differentiating factor in neuronal cells

Yao, H., Labudda, K., Rim, C., Capodieci, P., Loda, M. & Stork, P., 1995, In : Journal of Biological Chemistry. 270, 35, p. 20748-20753 6 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinases
Epidermal Growth Factor
Cyclic AMP
Intercellular Signaling Peptides and Proteins
Chemical activation
61 Citations (Scopus)

Cyclic AMP- and phorbol ester-induced transcriptional activation are mediated by the same enhancer element in the human vasoactive intestinal peptide gene

Fink, J. S., Verhave, M., Walton, K., Mandel, G. & Goodman, R., Feb 25 1991, In : Journal of Biological Chemistry. 266, 6, p. 3882-3887 6 p.

Research output: Contribution to journalArticle

Vasoactive Intestinal Peptide
Phorbol Esters
Cyclic AMP
Transcriptional Activation
Genes
110 Citations (Scopus)

Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1

Schmitt, J. M. & Stork, P., Jun 2001, In : Molecular and Cellular Biology. 21, 11, p. 3671-3683 13 p.

Research output: Contribution to journalArticle

Monomeric GTP-Binding Proteins
Cyclic AMP
NIH 3T3 Cells
Mitogen-Activated Protein Kinases
Growth
151 Citations (Scopus)

Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis

Forte, M., Gold, B. G., Marracci, G., Chaudhary, P., Basso, E., Johnsen, D., Yu, X., Fowlkes, J., Bernardi, P. & Bourdette, D., May 1 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 18, p. 7558-7563 6 p.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Multiple Sclerosis
Axons
Animal Models
Inflammation