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2014

Differential subcellular localization of SK3-containing channels in the hippocampus

Ballesteros-Merino, C., Watanabe, M., Shigemoto, R., Fukazawa, Y., Adelman, J. P. & Luján, R., Mar 2014, In : European Journal of Neuroscience. 39, 6, p. 883-892 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Distinct Ca2+ sources in dendritic spines of hippocampal CA1 Neurons Couple to SK and Kv4 Channels

Wang, K., Lin, M. T., Adelman, J. P. & Maylie, J., Jan 22 2014, In : Neuron. 81, 2, p. 379-387 9 p.

Research output: Contribution to journalArticle

31 Scopus citations
15 Scopus citations

Drosophila models of neuronal injury

Rooney, T. M. & Freeman, M. R., Apr 1 2014, In : ILAR Journal. 54, 3, p. 291-295 5 p., ilt057.

Research output: Contribution to journalArticle

8 Scopus citations

Fatty acids increase neuronal hypertrophy of Pten knockdown neurons

Fricano, C. J., DeSpenza, T., Frazel, P. W., Li, M., James O'Malley, A., Westbrook, G. L. & Luikart, B. W., Apr 23 2014, In : Frontiers in Molecular Neuroscience. 7, 1 APR, 30.

Research output: Contribution to journalArticle

13 Scopus citations

Glial wingless/wnt regulates glutamate receptor clustering and synaptic physiology at the Drosophila neuromuscular junction

Kerr, K. S., Fuentes-Medel, Y., Brewer, C., Barria, R., Ashley, J., Abruzzi, K. C., Sheehan, A., Tasdemir-Yilmaz, O. E., Freeman, M. R. & Budnik, V., Feb 25 2014, In : Journal of Neuroscience. 34, 8, p. 2910-2920 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

How LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transporters

Penmatsa, A. & Gouaux, E., Mar 1 2014, In : Journal of Physiology. 592, 5, p. 863-869 7 p.

Research output: Contribution to journalArticle

58 Scopus citations

Increasing small conductance Ca2+-activated potassium channel activity reverses ischemia-induced impairment of long-term potentiation

Orfila, J. E., Shimizu, K., Garske, A. K., Deng, G., Maylie, J., Traystman, R. J., Quillinan, N., Adelman, J. P. & Herson, P. S., Oct 1 2014, In : European Journal of Neuroscience. 40, 8, p. 3179-3188 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Live imaging of endogenous PSD-95 using ENABLED: A conditional strategy to fluorescently label endogenous proteins

Fortin, D. A., Tillo, S. E., Yang, G., Rah, J. C., Melander, J. B., Bai, S., Soler-Cedeño, O., Qin, M., Zemelman, B. V., Guo, C., Mao, T. & Zhong, H., Dec 10 2014, In : Journal of Neuroscience. 34, 50, p. 16698-16712 15 p.

Research output: Contribution to journalArticle

26 Scopus citations

Localization of SK2 channels relative to excitatory synaptic sites in the mouse developing Purkinje cells

Ballesteros-Merino, C., Martínez-Hernández, J., Aguado, C., Watanabe, M., Adelman, J. P. & Luján, R., Dec 15 2014, In : Frontiers in Neuroanatomy. 8, DEC, 154.

Research output: Contribution to journalArticle

3 Scopus citations

Neuroligin-1 knockdown reduces survival of adult-generated newborn hippocampal neurons

Schnell, E., Long, T. H., Bensen, A. S. L., Washburn, E. K. & Westbrook, G. L., Jan 1 2014, In : Frontiers in Neuroscience. 8 APR, 71.

Research output: Contribution to journalArticle

12 Scopus citations
11 Scopus citations

Neuron-Glia interactions through the heartless fgf receptor signaling pathway mediate morphogenesis of drosophila astrocytes

Stork, T., Sheehan, A., Tasdemir-Yilmaz, O. E. & Freeman, M. R., Jul 16 2014, In : Neuron. 83, 2, p. 388-403 16 p.

Research output: Contribution to journalArticle

94 Scopus citations

New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors

Liebscher, I., Ackley, B., Araç, D., Ariestanti, D. M., Aust, G., Bae, B. I., Bista, B. R., Bridges, J. P., Duman, J. G., Engel, F. B., Giera, S., Goffinet, A. M., Hall, R. A., Hamann, J., Hartmann, N., Lin, H. H., Liu, M., Luo, R., Mogha, A., Monk, K. R. & 12 others, Peeters, M. C., Prömel, S., Ressl, S., Schiöth, H. B., Sigoillot, S. M., Song, H., Talbot, W. S., Tall, G. G., White, J. P., Wolfrum, U., Xu, L. & Piao, X., Dec 1 2014, In : Annals of the New York Academy of Sciences. 1333, 1, p. 43-64 22 p.

Research output: Contribution to journalArticle

13 Scopus citations

NMDA receptor structures reveal subunit arrangement and pore architecture

Lee, C. H., Lü, W., Michel, J. C., Goehring, A., Du, J., Song, X. & Gouaux, E., Jan 1 2014, In : Nature. 511, 7508, p. 191-197 7 p.

Research output: Contribution to journalArticle

279 Scopus citations

Novel primate miRNAs coevolved with ancient target genes in germinal zone-specific expression patterns

Arcila, M. L., Betizeau, M., Cambronne, X. A., Guzman, E., Doerflinger, N., Bouhallier, F., Zhou, H., Wu, B., Rani, N., Bassett, D. S., Borello, U., Huissoud, C., Goodman, R. H., Dehay, C. & Kosik, K. S., Mar 19 2014, In : Neuron. 81, 6, p. 1255-1262 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Optical control of insulin release using a photoswitchable sulfonylurea

Broichhagen, J., Schönberger, M., Cork, S. C., Frank, J. A., Marchetti, P., Bugliani, M., Shapiro, A. M. J., Trapp, S., Rutter, G. A., Hodson, D. J. & Trauner, D., Oct 14 2014, In : Nature communications. 5, 5116.

Research output: Contribution to journalArticle

Open Access
64 Scopus citations

Phase-locking precision is enhanced by multiquantal release at an auditory hair cell ribbon synapse

Li, G. L., Cho, S. & von Gersdorff, H., Jan 1 2014, In : Neuron. 83, 6, p. 1404-1417 14 p.

Research output: Contribution to journalArticle

34 Scopus citations

PI3K Signaling and Stat92E Converge to Modulate Glial Responsiveness to Axonal Injury

Doherty, J., Sheehan, A. E., Bradshaw, R., Fox, A. N., Lu, T. Y. & Freeman, M. R., Jan 1 2014, In : PLoS Biology. 12, 11

Research output: Contribution to journalArticle

24 Scopus citations
22 Scopus citations

Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system

Wang, W., Whorton, M. R. & MacKinnon, R., Jan 1 2014, In : eLife. 3, p. e03671

Research output: Contribution to journalArticle

28 Scopus citations

Rapid in vivo forward genetic approach for identifying axon death genes in Drosophila

Neukomm, L. J., Burdett, T. C., Gonzalez, M. A., Züchner, S. & Freeman, M. R., Jul 8 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 27, p. 9965-9970 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Regulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (translocator protein of 18 kDa (TSPO))

Šileikyte, J., Blachly-Dyson, E., Sewell, R., Carpi, A., Menabò, R., Di Lisa, F., Ricchelli, F., Bernardi, P. & Forte, M., May 16 2014, In : Journal of Biological Chemistry. 289, 20, p. 13769-13781 13 p.

Research output: Contribution to journalArticle

113 Scopus citations

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

Goehring, A., Lee, C. H., Wang, K. H., Michel, J. C., Claxton, D. P., Baconguis, I., Althoff, T., Fischer, S., Garcia, K. C. & Gouaux, E., Nov 27 2014, In : Nature protocols. 9, 11, p. 2574-2585 12 p.

Research output: Contribution to journalArticle

156 Scopus citations

Separate GABA afferents to dopamine neurons mediate acute action of opioids, development of tolerance, and expression of withdrawal

Matsui, A., Jarvie, B. C., Robinson, B. G., Hentges, S. T. & Williams, J. T., Jun 18 2014, In : Neuron. 82, 6, p. 1346-1356 11 p.

Research output: Contribution to journalArticle

84 Scopus citations

Specialized postsynaptic morphology enhances neurotransmitter dilution and high-frequency signaling at an auditory synapse

Graydon, C. W., Cho, S., Diamond, J. S., Kachar, B., von Gersdorff, H. & Grimes, W. N., Jan 1 2014, In : Journal of Neuroscience. 34, 24, p. 8358-8372 15 p.

Research output: Contribution to journalArticle

17 Scopus citations

Structure and dynamics of AMPA receptor GluA2 in resting, pre-open, and desensitized states

Dürr, K. L., Chen, L., Stein, R. A., De Zorzi, R., Folea, I. M., Walz, T., McHaourab, H. S. & Gouaux, E., Aug 14 2014, In : Cell. 158, 4, p. 778-792 15 p.

Research output: Contribution to journalArticle

130 Scopus citations

The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation

Willer, T., Inamori, K. I., Venzke, D., Harvey, C., Morgensen, G., Hara, Y., Beltrán Valero de Bernabé, D., Yu, L., Wright, K. & Campbell, K. P., 2014, In : eLife. 3

Research output: Contribution to journalArticle

48 Scopus citations

The IGF-derived tripeptide Gly-Pro-Glu is a weak NMDA receptor agonist

Vaaga, C. E., Tovar, K. R. & Westbrook, G. L., Sep 15 2014, In : Journal of neurophysiology. 112, 6, p. 1241-1245 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

The rare DAT coding variant Val559 perturbs da neuron function, changes behavior, and alters in vivo responses to psychostimulants

Mergy, M. A., Gowrishankar, R., Gresch, P. J., Gantz, S. C., Williams, J., Davis, G. L., Wheeler, C. A., Stanwood, G. D., Hahn, M. K. & Blakely, R. D., Nov 4 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 44, p. E4779-E4788

Research output: Contribution to journalArticle

29 Scopus citations

Tonotopic organization of vertical cells in the dorsal cochlear nucleus of the CBA/J mouse

Muniak, M. A. & Ryugo, D. K., Mar 1 2014, In : Journal of Comparative Neurology. 522, 4, p. 937-949 13 p.

Research output: Contribution to journalArticle

13 Scopus citations
13 Scopus citations

X-ray structure of acid-sensing ion channel 1-snake toxin complex reveals open state of a Na+-selective channel

Baconguis, I., Bohlen, C. J., Goehring, A., Julius, D. & Gouaux, E., Feb 13 2014, In : Cell. 156, 4, p. 717-729 13 p.

Research output: Contribution to journalArticle

149 Scopus citations

X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.

Chen, L., Dürr, K. L. & Gouaux, E., Aug 29 2014, In : Science (New York, N.Y.). 345, 6200, p. 1021-1026 6 p.

Research output: Contribution to journalArticle

79 Scopus citations

X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors

Althoff, T., Hibbs, R. E., Banerjee, S. & Gouaux, E., Aug 21 2014, In : Nature. 512, 7514, p. 333-337 5 p.

Research output: Contribution to journalArticle

157 Scopus citations
2013

3D model of frequency representation in the cochlear nucleus of the CBA/J mouse

Muniak, M. A., Rivas, A., Montey, K. L., May, B. J., Francis, H. W. & Ryugo, D. K., May 1 2013, In : Journal of Comparative Neurology. 521, 7, p. 1510-1532 23 p.

Research output: Contribution to journalArticle

28 Scopus citations

Activation of axonal receptors by GABA spillover increases somatic firing

Pugh, J. R. & Jahr, C. E., Oct 25 2013, In : Journal of Neuroscience. 33, 43, p. 16924-16929 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Activation of extrasynaptic NMDARs at individual parallel fiber-molecular layer interneuron synapses in cerebellum

Nahir, B. & Jahr, C. E., Oct 14 2013, In : Journal of Neuroscience. 33, 41, p. 16323-16333 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Allosteric activation of functionally asymmetric RAF kinase dimers

Hu, J., Stites, E. C., Yu, H., Germino, E. A., Meharena, H. S., Stork, P. J. S., Kornev, A. P., Taylor, S. S. & Shaw, A. S., Aug 29 2013, In : Cell. 154, 5, p. 1036-1046 11 p.

Research output: Contribution to journalArticle

141 Scopus citations

An anti-inflammatory nod-like receptor is required for microglia development

Shiau, C. E., Monk, K. R., Joo, W. & Talbot, W. S., Dec 12 2013, In : Cell Reports. 5, 5, p. 1342-1352 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

A selective 5-HT1a receptor agonist improves respiration in a mouse model of Rett syndrome

Levitt, E. S., Hunnicutt, B. J., Knopp, S. J., Williams, J. T. & Bissonnette, J. M., Dec 1 2013, In : Journal of Applied Physiology. 115, 11, p. 1626-1633 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

BH3-only proteins Noxa, Bik, Bmf, and Bid activate Bax and Bak indirectly when studied in yeast model

Gérecová, G., Kopanicová, J., Jaká, P., Běhalová, L., Juhásová, B., Bhatia-Kiššová, I., Forte, M., Polčic, P. & Mentel, M., Dec 1 2013, In : FEMS Yeast Research. 13, 8, p. 747-754 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

B-Raf is required for positive selection and survival of DP cells, but not for negative selection of SP cells

Dillon, T. J., Takahashi, M., Li, Y., Tavisala, S., Murray, S. E., Moran, A. E., Parker, D. C. & Stork, P. J. S., Apr 1 2013, In : International Immunology. 25, 4, p. 259-269 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Caged naloxone reveals opioid signaling deactivation kineticss

Banghart, M. R., Williams, J. T., Shah, R. C., Lavis, L. D. & Sabatini, B. L., Nov 1 2013, In : Molecular pharmacology. 84, 5, p. 687-695 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Comparative phosphoproteomics reveals components of host cell invasion and post-transcriptional regulation during francisella infection

Nakayasu, E. S., Tempel, R., Cambronne, X. A., Petyuk, V. A., Jones, M. B., Gritsenko, M. A., Monroe, M. E., Yang, F., Smith, R. D., Adkins, J. N. & Heffron, F., Nov 1 2013, In : Molecular and Cellular Proteomics. 12, 11, p. 3297-3309 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A

Xu, J., Bauer, D. E., Kerenyi, M. A., Vo, T. D., Hou, S., Hsu, Y. J., Yao, H., Trowbridge, J. J., Mandel, G. & Orkin, S. H., Apr 16 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 16, p. 6518-6523 6 p.

Research output: Contribution to journalArticle

99 Scopus citations

Deletions within its subcellular targeting domain enhance the axon protective capacity of Nmnat2 in vivo

Milde, S., Fox, A. N., Freeman, M. R. & Coleman, M. P., Sep 23 2013, In : Scientific Reports. 3, 2567.

Research output: Contribution to journalArticle

20 Scopus citations

Dimers of mitochondrial ATP synthase form the permeability transition pore

Giorgio, V., Von Stockum, S., Antoniel, M., Fabbro, A., Fogolari, F., Forte, M., Glick, G. D., Petronilli, V., Zoratti, M., Szabó, I., Lippe, G. & Bernardi, P., Apr 9 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 15, p. 5887-5892 6 p.

Research output: Contribution to journalArticle

552 Scopus citations

Distinct modes of dopamine and GABA release in a dual transmitter neuron

Borisovska, M., Bensen, A. S. L., Chong, G. & Westbrook, G. L., Jan 30 2013, In : Journal of Neuroscience. 33, 5, p. 1790-1796 7 p.

Research output: Contribution to journalArticle

45 Scopus citations

Dysmyelination of auditory afferent axons increases the jitter of action potential timing during high-frequency firing

Kim, J. H., Renden, R. & von Gersdorff, H., May 29 2013, In : Journal of Neuroscience. 33, 22, p. 9402-9407 6 p.

Research output: Contribution to journalArticle

33 Scopus citations