Research Output 1987 2020

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1992

Second messenger regulation of the slowly activating, voltage-dependent potassium current (I(sK)) in Xenopus oocytes

Busch, A. E., Kavanaugh, M. P., Adelman, J. & North, R. A., 1992, In : Journal of Physiology. 446

Research output: Contribution to journalArticle

Second Messenger Systems
Xenopus
Oocytes
Potassium
24 Citations (Scopus)
Locus Coeruleus
Amphetamine
Cocaine
Antidepressive Agents
Neurons
15 Citations (Scopus)

Targeted expression of somatostatin in vasopressinergic magnocellular hypothalamic neurons of transgenic mice

Rubinstein, M., Liu, B., Goodman, R. & Low, M. J., 1992, In : Molecular and Cellular Neuroscience. 3, 2, p. 152-161 10 p.

Research output: Contribution to journalArticle

Somatostatin
Transgenic Mice
Neurons
Transgenes
Vasopressins
722 Citations (Scopus)

The time course of glutamate in the synaptic cleft

Clements, J. D., Lester, R. A. J., Tong, G., Jahr, C. & Westbrook, G., Nov 27 1992, In : Science. 258, 5087, p. 1498-1501 4 p.

Research output: Contribution to journalArticle

Glutamic Acid
AMPA Receptors
N-Methyl-D-Aspartate Receptors
Synapses
Neurotransmitter Agents
119 Citations (Scopus)

Toward the molecular structure of the mitochondrial channel, VDAC

Mannella, C. A., Forte, M. & Colombini, M., Feb 1992, In : Journal of Bioenergetics and Biomembranes. 24, 1, p. 7-19 13 p.

Research output: Contribution to journalArticle

Structural Models
Molecular Structure
Electron Microscopy
Protein Domains
14 Citations (Scopus)

Vasoactive intestinal polypeptide gene expression in the developing human gastrointestinal tract

Facer, P., Bishop, A. E., Moscoso, G., Terenghi, G., Liu, Y. F., Goodman, R., Legon, S. & Polak, J. M., 1992, In : Gastroenterology. 102, 1, p. 47-55 9 p.

Research output: Contribution to journalArticle

Vasoactive Intestinal Peptide
Gastrointestinal Tract
Gene Expression
Pregnancy
Ganglia
1993
24 Citations (Scopus)
Protein Subunits
GTP-Binding Proteins
Diptera
Drosophila
Second Messenger Systems
32 Citations (Scopus)

A false transmitter at excitatory synapses

Zhong Pan, Z., Tong, G. & Jahr, C., 1993, In : Neuron. 11, 1, p. 85-91 7 p.

Research output: Contribution to journalArticle

Synapses
Excitatory Postsynaptic Potentials
Glutamic Acid
Excitatory Amino Acid Agonists
Neurotransmitter Agents
436 Citations (Scopus)

Calcium-induced actin depolymerization reduces NMDA channel activity

Rosenmund, C. & Westbrook, G., 1993, In : Neuron. 10, 5, p. 805-814 10 p.

Research output: Contribution to journalArticle

N-Methylaspartate
Actins
Calcium
Phalloidine
Actin Cytoskeleton
112 Citations (Scopus)

Calcium permeability of the N-methyl-D-aspartate receptor channel in hippocampal neurons in culture

Jahr, C. & Stevens, C. F., Dec 15 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 24, p. 11573-11577 5 p.

Research output: Contribution to journalArticle

N-Methyl-D-Aspartate Receptors
Permeability
Calcium
Neurons
Calcium Channels
1 Citation (Scopus)

Chapter 8 Receptors for 5-hydroxytryptamine

Bobker, D. H. & Williams, J., 1993, In : New Comprehensive Biochemistry. 24, C, p. 221-250 30 p.

Research output: Contribution to journalArticle

5-Methoxytryptamine
N-Methyl-3,4-methylenedioxyamphetamine
Spiperone
8-Hydroxy-2-(di-n-propylamino)tetralin
5-Hydroxytryptophan
43 Citations (Scopus)

Cloning and expression of two structurally distinct receptor-linked protein-tyrosine phosphatases generated by RNA processing from a single gene

Pan, M. G., Rim, C., Lu, K. P., Florio, T. & Stork, P., Sep 15 1993, In : Journal of Biological Chemistry. 268, 26, p. 19284-19291 8 p.

Research output: Contribution to journalArticle

Protein Tyrosine Phosphatases
Cloning
Organism Cloning
Genes
RNA
205 Citations (Scopus)

Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel

Blachly-Dyson, E., Zambronicz, E. B., Yu, W. H., Adams, V., McCabe, E. R. B., Adelman, J., Colombini, M. & Forte, M., Jan 25 1993, In : Journal of Biological Chemistry. 268, 3, p. 1835-1841 7 p.

Research output: Contribution to journalArticle

Voltage-Dependent Anion Channels
Cloning
Mitochondrial Membranes
Ion Channels
Yeast
228 Citations (Scopus)

Dopamine D1 receptors facilitate transmitter release

Cameron, D. L. & Williams, J., Nov 25 1993, In : Nature. 366, 6453, p. 344-347 4 p.

Research output: Contribution to journalArticle

Flupenthixol
Dopamine D1 Receptors
Synaptic Potentials
Mesencephalon
gamma-Aminobutyric Acid

Effects of a proline residue in the S4 regions of a concatenated rat brain channel expressed in Xenopus oocytes

Hurst, R. S., Kavanaugh, M. P., North, R. A. & Adelman, J., 1993, In : Journal of Physiology. 467

Research output: Contribution to journalArticle

Xenopus
Proline
Oocytes
Brain
47 Citations (Scopus)
Leucine Zippers
Phosphorylation
Basic-Leucine Zipper Transcription Factors
Transcriptional Activation
Proteins
25 Citations (Scopus)
Long-Term Potentiation
Glutamate Receptors
Astrocytes
Synapses
Glutamic Acid
275 Citations (Scopus)

Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium

Legendre, P., Rosenmund, C. & Westbrook, G., 1993, In : Journal of Neuroscience. 13, 2, p. 674-684 11 p.

Research output: Contribution to journalArticle

N-Methylaspartate
Calcium
Neurons
Egtazic Acid
Adenosine Triphosphate
112 Citations (Scopus)

Interactions between the glycine and glutamate binding sites of the NMDA receptor

Lester, R. A. J., Tong, G. & Jahr, C., 1993, In : Journal of Neuroscience. 13, 3, p. 1088-1096 9 p.

Research output: Contribution to journalArticle

N-Methyl-D-Aspartate Receptors
Glycine
Glutamic Acid
Binding Sites
Glutamate Receptors
24 Citations (Scopus)

Isolation of Drosophila CREB-B: A novel CRE-binding protein

Usui, T., Smolik, S. M. & Goodman, R., 1993, In : DNA and Cell Biology. 12, 7, p. 589-595 7 p.

Research output: Contribution to journalArticle

Drosophila
Carrier Proteins
Genes
Transcriptional Activation
DNA
104 Citations (Scopus)

Mapping of residues forming the voltage sensor of the voltage-dependent anion-selective channel

Thomas, L., Blachly-Dyson, E., Colombini, M. & Forte, M., Jun 15 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 12, p. 5446-5449 4 p.

Research output: Contribution to journalArticle

Voltage-Dependent Anion Channels
Ion Channel Gating
Site-Directed Mutagenesis
Ion Channels
Membrane Proteins
57 Citations (Scopus)

Modulation by serotonin of the neurons in rat nucleus raphe magnus in vitro

Pan, Z. Z., Wessendorf, M. W. & Williams, J., 1993, In : Neuroscience. 54, 2, p. 421-429 9 p.

Research output: Contribution to journalArticle

Serotonin
Neurons
Opioid Analgesics
Inhibitory Postsynaptic Potentials
Nucleus Raphe Magnus
107 Citations (Scopus)
Metabotropic Glutamate Receptors
Calcium
Neurons
Guanosine Triphosphate
Conotoxins
473 Citations (Scopus)

Nonuniform probability of glutamate release at a hippocampal synapse

Rosenmund, C., Clements, J. D. & Westbrook, G., 1993, In : Science. 262, 5134, p. 754-757 4 p.

Research output: Contribution to journalArticle

Synapses
Glutamic Acid
Neuronal Plasticity
Dizocilpine Maleate
Long-Term Potentiation
29 Citations (Scopus)

Opioid-glutamate interactions in rat locus coeruleus neurons

Oleskevich, S., Clements, J. D. & Williams, J., 1993, In : Journal of Neurophysiology. 70, 3, p. 931-937 7 p.

Research output: Contribution to journalArticle

Locus Coeruleus
Ala(2)-MePhe(4)-Gly(5)-enkephalin
Opioid Analgesics
Glutamic Acid
Neurons
1671 Citations (Scopus)

Phosphorylated CREB binds specifically to the nuclear protein CBP

Chrivia, J. C., Kwok, R. P. S., Lamb, N., Hagiwara, M., Montminy, M. R. & Goodman, R., Oct 28 1993, In : Nature. 365, 6449

Research output: Contribution to journalArticle

CREB-Binding Protein
Nuclear Proteins
Protein Binding
Cyclic AMP-Dependent Protein Kinases
General Transcription Factors
115 Citations (Scopus)

Rundown of N-methyl-D-aspartate channels during whole-cell recording in rat hippocampal neurons: Role of Ca2+ and ATP

Rosenmund, C. & Westbrook, G., 1993, In : Journal of Physiology. 470, p. 705-729 25 p.

Research output: Contribution to journalArticle

Patch-Clamp Techniques
N-Methylaspartate
Adenosine Triphosphate
Neurons
Phosphoric Monoester Hydrolases
110 Citations (Scopus)

Single amino acid substitution affects desensitization of the 5-hydroxytryptamine type 3 receptor expressed in Xenopus oocytes

Yakel, J. L., Lagrutta, A., Adelman, J. & North, R. A., Jun 1 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 11, p. 5030-5033 4 p.

Research output: Contribution to journalArticle

Receptors, Serotonin, 5-HT3
Amino Acid Substitution
Xenopus
Oocytes
Serotonin
100 Citations (Scopus)

The min K channel underlies the cardiac potassium current IKs and mediates species-specific responses to protein kinase C

Varnum, M. D., Busch, A. E., Bond, C. T., Maylie, J. & Adelman, J., Dec 15 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 24, p. 11528-11532 5 p.

Research output: Contribution to journalArticle

Protein Kinase C
Potassium
Muscle Cells
Guinea Pigs
Oocytes
101 Citations (Scopus)

κ-Opioid receptors also increase potassium conductance

Grudt, T. J. & Williams, J., Dec 1 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 23, p. 11429-11432 4 p.

Research output: Contribution to journalArticle

Opioid Receptors
Potassium
Naloxone
Opioid Analgesics
Substantia Gelatinosa
1994
1 Citation (Scopus)

[33] Vaccinia virus systems for expression of Gα genes in S49 cells

Quan, F. & Forte, M., 1994, In : Methods. 237, p. 436-445 10 p.

Research output: Contribution to journalArticle

Phosphatidylethanolamines
Genetic Vectors
Signal transduction
Mammals
Viruses
311 Citations (Scopus)

Anchoring of protein kinase A is required for modulation of AMPA/kainate receptors on hippocampal neurons

Rosenmund, C., Carr, D., Bergeson, S. E., Nilaver, G., Scott, J. D. & Westbrook, G., Apr 28 1994, In : Nature. 368, 6474, p. 853-856 4 p.

Research output: Contribution to journalArticle

Kainic Acid Receptors
AMPA Receptors
Cyclic AMP-Dependent Protein Kinases
Protein Kinases
Neurons
73 Citations (Scopus)

A second gene for gonadotropin-releasing hormone: cDNA and expression pattern in the brain

White, S. A., Bond, C. T., Francis, R. C., Kasten, T. L., Fernald, R. D. & Adelman, J., Feb 15 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 4, p. 1423-1427 5 p.

Research output: Contribution to journalArticle

Gonadotropin-Releasing Hormone
Complementary DNA
Brain
Genes
Peptides
127 Citations (Scopus)

A structural determinant of differential sensitivity of cloned inward rectifier K+ channels to intracellular spermine

Fakler, B., Brändle, U., Bond, C., Glowatzki, E., König, C., Adelman, J., Zenner, H. P. & Ruppersberg, J. P., Dec 19 1994, In : FEBS Letters. 356, 2-3, p. 199-203 5 p.

Research output: Contribution to journalArticle

Inwardly Rectifying Potassium Channel
Spermine
Mutagenesis
Site-Directed Mutagenesis
Glutamic Acid
287 Citations (Scopus)

Block of glutamate transporters potentiates postsynaptic excitation

Tong, G. & Jahr, C., 1994, In : Neuron. 13, 5, p. 1195-1203 9 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
AMPA Receptors
Tacrine
Glutamate Receptors
Synaptic Transmission
94 Citations (Scopus)

Cloned Ca2+-dependent K+ channel modulated by a functionally associated protein kinase

Esguerra, M., Wang, J., Foster, C. D., Adelman, J., North, R. A. & Levitan, I. B., Jun 16 1994, In : Nature. 369, 6481, p. 563-565 3 p.

Research output: Contribution to journalArticle

Protein Kinases
Oocytes
Proteins
Adenosine Triphosphate
Phosphorylation
123 Citations (Scopus)

Cloning, expression, and localization of a chloride-facilitated, cocaine-sensitive serotonin transporter from Drosophila melanogaster

Demchyshyn, L. L., Pristupa, Z. B., Sugamori, K. S., Barker, E. L., Blakely, R. D., Wolfgang, W. J., Forte, M. & Niznik, H. B., May 24 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 11, p. 5158-5162 5 p.

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Drosophila melanogaster
Cocaine
Organism Cloning
Chlorides
150 Citations (Scopus)

Cloning and expression of a family of inward rectifier potassium channels

Bond, C. T., Pessia, M., Xia, X. M., Lagrutta, A., Kavanaugh, M. P. & Adelman, J., 1994, In : Receptors and Channels. 2, 3, p. 183-191 9 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Recombinant Fusion Proteins
Inwardly Rectifying Potassium Channel
Amino Acid Sequence Homology
Organ Specificity
218 Citations (Scopus)

Cloning and expression of a new member of the L-2-amino-4-phosphonobutyric acid-sensitive class of metabotropic glutamate receptors

Saugstad, J., Kinzie, J. M., Mulvihill, E. R., Segerson, T. P. & Westbrook, G., Mar 1994, In : Molecular Pharmacology. 45, 3, p. 367-372 6 p.

Research output: Contribution to journalArticle

Metabotropic Glutamate Receptors
Organism Cloning
Olfactory Bulb
Neurons
Clone Cells
166 Citations (Scopus)

Cloning and functional expression of a rat heart KATP channel

Ashford, M. L. J., Bond, C. T., Blair, T. A. & Adelman, J., 1994, In : Nature. 370, 6489, p. 456-459 4 p.

Research output: Contribution to journalArticle

KATP Channels
Organism Cloning
Nucleotides
Adenosine Triphosphate
Pinacidil
4 Citations (Scopus)

Cloning and sequence analysis of a Drosophila melanogaster cDNA encoding IMP dehydrogenase

Sifri, C. D., Wilson, K., Smolik, S., Forte, M. & Ullman, B., Jan 18 1994, In : BBA - Gene Structure and Expression. 1217, 1, p. 101-102 2 p.

Research output: Contribution to journalArticle

IMP Dehydrogenase
Cloning
Drosophila melanogaster
Drosophila
Sequence Analysis
159 Citations (Scopus)

Cocaine inhibits GABA release in the VTA through endogenous 5-HT

Cameron, D. L. & Williams, J., 1994, In : Journal of Neuroscience. 14, 11 I, p. 6763-6767 5 p.

Research output: Contribution to journalArticle

Ventral Tegmental Area
Cocaine
gamma-Aminobutyric Acid
Serotonin
Dopaminergic Neurons
3 Citations (Scopus)

Cytoplasmic and cytoskeletal regulation of glutamate receptor channels

Westbrook, G., Apr 1994, In : Seminars in Neuroscience. 6, 2, p. 97-103 7 p.

Research output: Contribution to journalArticle

Glutamate Receptors
Cytoskeletal Proteins
Calcium
Isoxazoles
Post-Synaptic Density
148 Citations (Scopus)

Functional differences among alternatively spliced variants of Slowpoke, a Drosophila calcium-activated potassium channel

Lagrutta, A., Shen, K-Z., North, R. A. & Adelman, J., Aug 12 1994, In : Journal of Biological Chemistry. 269, 32, p. 20347-20351 5 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Drosophila
Oocytes
Large-Conductance Calcium-Activated Potassium Channels
Calcium
77 Citations (Scopus)

Glutamate receptor update

Westbrook, G., 1994, In : Current Opinion in Neurobiology. 4, 3, p. 337-346 10 p.

Research output: Contribution to journalArticle

RNA Editing
Metabotropic Glutamate Receptors
AMPA Receptors
Glutamate Receptors
Binding Sites
61 Citations (Scopus)

Human Genes Encoding the Voltage-Dependent Anion Channel (VDAC) of the Outer Mitochondrial Membrane: Mapping and Identification of Two New Isoforms

Blachly-Dyson, E., Baldini, A., Litt, M., McCabe, E. R. B. & Forte, M., Mar 1 1994, In : Genomics. 20, 1, p. 62-67 6 p.

Research output: Contribution to journalArticle

Voltage-Dependent Anion Channels
Mitochondrial Membranes
Protein Isoforms
Genes
Glycerol Kinase
28 Citations (Scopus)

Kinetics of AP5 dissociation from NMDA receptors: Evidence for two identical cooperative binding sites

Clements, J. D. & Westbrook, G., 1994, In : Journal of Neurophysiology. 71, 6, p. 2566-2569 4 p.

Research output: Contribution to journalArticle

N-Methylaspartate
N-Methyl-D-Aspartate Receptors
Binding Sites
2-Amino-5-phosphonovalerate
Neurons
32 Citations (Scopus)

Modulatory function of CREB·CREMα heterodimers depends upon CREMα phosphorylation

Loriaux, M., Brennan, R. G. & Goodman, R., Nov 18 1994, In : Journal of Biological Chemistry. 269, 46, p. 28839-28843 5 p.

Research output: Contribution to journalArticle

Phosphorylation
Cyclic AMP-Dependent Protein Kinases
Carrier Proteins
Chemical activation
Proteins
550 Citations (Scopus)

Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ or κ opioid receptor type

Bunzow, J. R., Saez, C., Mortrud, M., Bouvier, C., Williams, J., Low, M. & Grandy, D., Jun 27 1994, In : FEBS Letters. 347, 2-3, p. 284-288 5 p.

Research output: Contribution to journalArticle

Cloning
Molecular Cloning
Opioid Receptors
Tissue Distribution
Rats
252 Citations (Scopus)

Multivesicular release from excitatory synapses of cultured hippocampal neurons

Tong, G. & Jahr, C., 1994, In : Neuron. 12, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

N-Methyl-D-Aspartate Receptors
Synapses
AMPA Receptors
Neurons
Exocytosis