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2017

Phosphorylation of Rap1 by cAMP-dependent protein kinase (PKA) creates a binding site for KSR to sustain ERK activation by cAMP

Takahashi, M., Li, Y., Dillon, T. J. & Stork, P., Jan 27 2017, In : Journal of Biological Chemistry. 292, 4, p. 1449-1461 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Phosphorylation of the C-Raf N region promotes Raf dimerization

Takahashi, M., Li, Y., Dillon, T. J., Kariya, Y. & Stork, P., Oct 1 2017, In : Molecular and Cellular Biology. 37, 19, e00132-17.

Research output: Contribution to journalArticle

5 Scopus citations

Presynaptic gain control by endogenous cotransmission of dopamine and GABA in the olfactory bulb

Vaaga, C. E., Yorgason, J. T., Williams, J. & Westbrook, G., Mar 1 2017, In : Journal of Neurophysiology. 117, 3, p. 1163-1170 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Regulation of mitochondria-dynactin interaction and mitochondrial retrograde transport in axons

Drerup, C. M., Herbert, A. L., Monk, K. R. & Nechiporuk, A. V., Apr 17 2017, In : eLife. 6, e22234.

Research output: Contribution to journalArticle

10 Scopus citations

REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation- differentiation balance in the developing brain

Monaghan, C. E., Nechiporuk, T., Jeng, S., McWeeney, S. K., Wang, J., Rosenfeld, M. G. & Mandel, G., Jan 17 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 3, p. E406-E415

Research output: Contribution to journalArticle

18 Scopus citations

Short-term depression of sprouted mossy fiber synapses from adult-born granule cells

Hendricks, W. D., Chen, Y., Bensen, A. L., Westbrook, G. & Schnell, E., Jun 7 2017, In : Journal of Neuroscience. 37, 23, p. 5722-5735 14 p.

Research output: Contribution to journalArticle

13 Scopus citations

Site-directed RNA repair of endogenous Mecp2 RNA in neurons

Sinnamon, J. R., Kim, S. Y., Corson, G. M., Song, Z., Nakai, H., Adelman, J. & Mandel, G., Oct 31 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 44, p. E9395-E9402

Research output: Contribution to journalArticle

21 Scopus citations

Stage-specific functions of Semaphorin7A during adult hippocampal neurogenesis rely on distinct receptors

Jongbloets, B. C., Lemstra, S., Schellino, R., Broekhoven, M. H., Parkash, J., Hellemons, A. J. C. G. M., Mao, T., Giacobini, P., Van Praag, H., De Marchis, S., Ramakers, G. M. J. & Pasterkamp, R. J., Mar 10 2017, In : Nature communications. 8, 14666.

Research output: Contribution to journalArticle

7 Scopus citations

Synaptotagmin 7 confers frequency invariance onto specialized depressing synapses

Turecek, J., Jackman, S. L. & Regehr, W. G., Nov 23 2017, In : Nature. 551, 7681, p. 503-506 4 p.

Research output: Contribution to journalArticle

22 Scopus citations

The coupling between Ca2+ channels and the exocytotic Ca2+ sensor at hair cell ribbon synapses varies tonotopically along the mature cochlea

Johnson, S. L., Olt, J., Cho, S., Von Gersdorff, H. & Marcotti, W., Mar 1 2017, In : Journal of Neuroscience. 37, 9, p. 2471-2484 14 p.

Research output: Contribution to journalArticle

19 Scopus citations

The secreted neurotrophin spätzle 3 promotes glial morphogenesis and supports neuronal survival and function

Coutinho-Budd, J. C., Sheehan, A. E. & Freeman, M. R., Oct 15 2017, In : Genes and Development. 31, 20, p. 2023-2038 16 p.

Research output: Contribution to journalArticle

15 Scopus citations

Tuning auditory synapses for resilience, reliability and precision

Lujan, B. & Von Gersdorff, H., Feb 1 2017, In : Journal of Physiology. 595, 3, p. 621-622 2 p.

Research output: Contribution to journalArticle

Two-color, one-photon uncaging of glutamate and GABA

Passlick, S., Kramer, P. F., Richers, M. T., Williams, J. T. & Ellis-Davies, G. C. R., Nov 2017, In : PloS one. 12, 11, e0187732.

Research output: Contribution to journalArticle

6 Scopus citations

Whole genome sequencing-based mapping and candidate identification of mutations from fixed zebrafish tissue

Sanchez, N. E., Harty, B. L., O'Reilly-Pol, T., Ackerman, S. D., Herbert, A. L., Holmgren, M., Johnson, S. L., Gray, R. S. & Monk, K. R., Oct 1 2017, In : G3: Genes, Genomes, Genetics. 7, 10, p. 3415-3425 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2016

A comprehensive excitatory input map of the striatum reveals novel functional organization

Hunnicutt, B. J., Jongbloets, B. C., Birdsong, W. T., Gertz, K. J., Zhong, H. & Mao, T., Nov 28 2016, In : eLife. 5, November2016, e19103.

Research output: Contribution to journalArticle

102 Scopus citations

Activity-Dependent Plasticity of Spike Pauses in Cerebellar Purkinje Cells

Grasselli, G., He, Q., Wan, V., Adelman, J., Ohtsuki, G. & Hansel, C., Mar 22 2016, In : Cell Reports. 14, 11, p. 2546-2553 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Acute and crucial requirement for MeCP2 function upon transition from early to late adult stages of brain maturation

Du, F., Nguyen, M. V. C., Karten, A., Felice, C. A., Mandel, G. & Ballas, N., May 1 2016, In : Human molecular genetics. 25, 9, p. 1690-1702 13 p., ddw038.

Research output: Contribution to journalArticle

7 Scopus citations

AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB

Hornick, N. I., Doron, B., Abdelhamed, S., Huan, J., Harrington, C. A., Shen, R., Cambronne, X. A., Verghese, S. C. & Kurre, P., Sep 6 2016, In : Science signaling. 9, 444, ra88.

Research output: Contribution to journalArticle

53 Scopus citations

Architecture of fully occupied GluA2 AMPA receptor-TARP complex elucidated by cryo-EM

Zhao, Y., Chen, S., Yoshioka, C., Baconguis, I. & Gouaux, E., Jul 1 2016, In : Nature. 536, 7614, p. 108-111 4 p.

Research output: Contribution to journalArticle

56 Scopus citations

Biosensor reveals multiple sources for mitochondrial NAD+

Cambronne, X. A., Stewart, M. L., Kim, D., Jones-Brunette, A. M., Morgan, R. K., Farrens, D. L., Cohen, M. S. & Goodman, R. H., Jun 17 2016, In : Science. 352, 6292, p. 1474-1477 4 p.

Research output: Contribution to journalArticle

125 Scopus citations

Calcium Release from Stores Inhibits GIRK

Kramer, P. F. & Williams, J., Dec 20 2016, In : Cell Reports. 17, 12, p. 3246-3255 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Cell-specific Profiling of Nascent Proteomes Using Orthogonal Enzyme-mediated Puromycin Incorporation

Barrett, R. M., Liu, H. W., Jin, H., Goodman, R. & Cohen, M., Jun 17 2016, In : ACS Chemical Biology. 11, 6, p. 1532-1536 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Early exposure to Aroclor 1254 in vivo disrupts the functional synaptic development of newborn hippocampal granule cells

Parent, A. S., Pinson, A., Woods, N., Chatzi, C., Vaaga, C. E., Bensen, A., Gérard, A., Thome, J. P., Bourguignon, J. P. & Westbrook, G. L., Dec 1 2016, In : European Journal of Neuroscience. 44, 12, p. 3001-3010 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Endothelial SK3 channel-associated ca2+ microdomains modulate blood pressure

Yap, F. C., Weber, D. S., Taylor, M. S., Townsley, M. I., Comer, B. S., Maylie, J., Adelman, J. P. & Lin, M. T., May 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 310, 9, p. H1151-H1163

Research output: Contribution to journalArticle

12 Scopus citations

ERK5 induces ankrd1 for catecholamine biosynthesis and homeostasis in adrenal medullary cells

Obara, Y., Nagasawa, R., Nemoto, W., Pellegrino, M. J., Takahashi, M., Habecker, B. A., Stork, P. J. S., Ichiyanagi, O., Ito, H., Tomita, Y., Ishii, K. & Nakahata, N., Mar 1 2016, In : Cellular Signalling. 28, 3, p. 177-189 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Fast, Temperature-Sensitive and Clathrin-Independent Endocytosis at Central Synapses

Delvendahl, I., Vyleta, N. P., Von Gersdorff, H. & Hallermann, S., May 4 2016, In : Neuron. 90, 3, p. 492-498 7 p.

Research output: Contribution to journalArticle

50 Scopus citations

Fatigue in rapsyn-deficient zebrafish reflects defective transmitter release

Wen, H., Hubbard, J. M., Wang, W. C. & Brehm, P., Oct 19 2016, In : Journal of Neuroscience. 36, 42, p. 10870-10882 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Gpr126/Adgrg6 has Schwann cell autonomous and nonautonomous functions in peripheral nerve injury and repair

Mogha, A., Harty, B. L., Carlin, D., Joseph, J., Sanchez, N. E., Suter, U., Piao, X., Cavalli, V. & Monk, K. R., Dec 7 2016, In : Journal of Neuroscience. 36, 49, p. 12351-12367 17 p.

Research output: Contribution to journalArticle

23 Scopus citations

IK1 channels do not contribute to the slow afterhyperpolarization in pyramidal neurons

Wang, K., Mateos-Aparicio, P., Hönigsperger, C., Raghuram, V., Wu, W. W., Ridder, M. C., Sah, P., Maylie, J., Storm, J. F. & Adelman, J. P., Jan 14 2016, In : eLife. 5, JANUARY2016, e11206.

Research output: Contribution to journalArticle

17 Scopus citations

Mechanism of NMDA Receptor Inhibition and Activation

Zhu, S., Stein, R. A., Yoshioka, C., Lee, C. H., Goehring, A., McHaourab, H. S. & Gouaux, E., Apr 21 2016, In : Cell. 165, 3, p. 704-714 11 p.

Research output: Contribution to journalArticle

92 Scopus citations

Membrane palmitoylated protein 2 is a synaptic scaffold protein required for synaptic SK2-containing channel function

Kim, G., Luján, R., Schwenk, J., Kelley, M. H., Aguado, C., Watanabe, M., Fakler, B., Maylie, J. & Adelman, J. P., Feb 12 2016, In : eLife. 5, FEBRUARY2016, e12637.

Research output: Contribution to journalArticle

5 Scopus citations

Neuromodulators signal through astrocytes to alter neural circuit activity and behaviour

Ma, Z., Stork, W. T., Bergles, D. E. & Freeman, M., 2016, In : Nature. 539, 7629, p. 428-432 5 p.

Research output: Contribution to journalArticle

66 Scopus citations

Nonequivalent release sites govern synaptic depression

Wen, H., McGinley, M. J., Mandel, G. & Brehm, P., Jan 19 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 3, p. E378-E386

Research output: Contribution to journalArticle

8 Scopus citations

N-Phenylbenzamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore

Roy, S., Šileikyte, J., Neuenswander, B., Hedrick, M. P., Chung, T. D. Y., Aubé, J., Schoenen, F. J., Forte, M. A. & Bernardi, P., Feb 4 2016, In : ChemMedChem. 11, 3, p. 283-288 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

Optogenetic Control of Mouse Outer Hair Cells

Wu, T., Ramamoorthy, S., Wilson, T., Chen, F., Porsov, E., Subhash, H., Foster, S., Zhang, Y., Omelchenko, I., Bateschell, M., Wang, L., Brigande, J., Jiang, Z-G., Mao, T. & Nuttall, A., Jan 19 2016, In : Biophysical Journal. 110, 2, p. 493-502 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Parallel processing of afferent olfactory sensory information

Vaaga, C. E. & Westbrook, G. L., Nov 15 2016, In : Journal of Physiology. 594, 22, p. 6715-6732 18 p.

Research output: Contribution to journalArticle

11 Scopus citations

PARP6 is a Regulator of Hippocampal Dendritic Morphogenesis

Huang, J. Y., Wang, K., Vermehren-Schmaedick, A., Adelman, J. P. & Cohen, M. S., Jan 4 2016, In : Scientific Reports. 6, 18512.

Research output: Contribution to journalArticle

13 Scopus citations

Photoswitchable diacylglycerols enable optical control of protein kinase C

Frank, J. A., Yushchenko, D. A., Hodson, D. J., Lipstein, N., Nagpal, J., Rutter, G. A., Rhee, J. S., Gottschalk, A., Brose, N., Schultz, C. & Trauner, D., Sep 1 2016, In : Nature Chemical Biology. 12, 9, p. 755-762 8 p.

Research output: Contribution to journalArticle

51 Scopus citations

Postsynaptic, not presynaptic NMDA receptors are required for spike-timing-dependent LTD induction

Carter, B. C. & Jahr, C., Jul 11 2016, (Accepted/In press) In : Nature Neuroscience.

Research output: Contribution to journalArticle

24 Scopus citations

Postsynaptic Plasticity Triggered by Ca2+-Permeable AMPA Receptor Activation in Retinal Amacrine Cells

Kim, M. H. & von Gersdorff, H., Feb 3 2016, In : Neuron. 89, 3, p. 507-520 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

Prevalent presence of periodic actin-spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species

He, J., Zhou, R., Wu, Z., Carrasco, M. A., Kurshan, P. T., Farley, J. E., Simon, D. J., Wang, G., Han, B., Hao, J., Heller, E., Freeman, M. R., Shen, K., Maniatis, T., Tessier-Lavigne, M. & Zhuang, X., May 24 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 21, p. 6029-6034 6 p.

Research output: Contribution to journalArticle

68 Scopus citations

Protein kinase A-independent Ras protein activation cooperates with Rap1 protein to mediate activation of the extracellular signal-regulated kinases (ERK) by cAMP

Li, Y., Dillon, T. J., Takahashi, M., Earley, K. T. & Stork, P., Oct 7 2016, In : Journal of Biological Chemistry. 291, 41, p. 21584-21595 12 p.

Research output: Contribution to journalArticle

13 Scopus citations
15 Scopus citations

SK channels and calmodulin

Adelman, J., Jan 1 2016, In : Channels. 10, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6

Küffer, A., Lakkaraju, A. K. K., Mogha, A., Petersen, S. C., Airich, K., Doucerain, C., Marpakwar, R., Bakirci, P., Senatore, A., Monnard, A., Schiavi, C., Nuvolone, M., Grosshans, B., Hornemann, S., Bassilana, F., Monk, K. R. & Aguzzi, A., Aug 8 2016, In : Nature. 536, 7617, p. 464-468 5 p.

Research output: Contribution to journalArticle

80 Scopus citations

The REST remodeling complex protects genomic integrity during embryonic neurogenesis

Nechiporuk, T., McGann, J., Mullendorff, K., Hsieh, J., Wurst, W., Floss, T. & Mandel, G., Jan 8 2016, In : eLife. 5, JANUARY2016, e09584.

Research output: Contribution to journalArticle

25 Scopus citations

Thermostabilization, expression, purification, and crystallization of the human serotonin transporter bound to S-citalopram

Coleman, J. A., Green, E. M. & Gouaux, E., Nov 27 2016, In : Journal of Visualized Experiments. 2016, 117, e54792.

Research output: Contribution to journalArticle

8 Scopus citations
11 Scopus citations

X-ray structures and mechanism of the human serotonin transporter

Coleman, J. A., Green, E. M. & Gouaux, E., Apr 21 2016, In : Nature. 532, 7599, p. 334-339 6 p.

Research output: Contribution to journalArticle

230 Scopus citations

X-ray structures define human P2X 3 receptor gating cycle and antagonist action

Mansoor, S. E., Lü, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E. & Gouaux, E., Sep 14 2016, In : Nature. 538, 7623, p. 66-71 6 p.

Research output: Contribution to journalArticle

83 Scopus citations