Research Output 1987 2019

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2002
135 Citations (Scopus)

μ-opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization

Alvarez, V. A., Arttamangkul, S., Dang, V., Salem, A., Whistler, J. L., Von Zastrow, M., Grandy, D. & Williams, J., Jul 1 2002, In : Journal of Neuroscience. 22, 13, p. 5769-5776 8 p.

Research output: Contribution to journalArticle

Opioid Receptors
Endocytosis
Locus Coeruleus
HEK293 Cells
Potassium
2001
126 Citations (Scopus)

Acetylation of nuclear hormone receptor-interacting protein RIP140 regulates binding of the transcriptional corepressor CtBP

Vo, N., Fjeld, C. & Goodman, R., 2001, In : Molecular and Cellular Biology. 21, 18, p. 6181-6188 8 p.

Research output: Contribution to journalArticle

Receptor-Interacting Protein Serine-Threonine Kinases
Co-Repressor Proteins
Acetylation
Cytoplasmic and Nuclear Receptors
Carrier Proteins
308 Citations (Scopus)

Acid-sensing ion channel 3 matches the acid-gated current in cardiac ischemia-sensing neurons

Sutherland, S. P., Benson, C. J., Adelman, J. & McCleskey, E. W., Jan 16 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 2, p. 711-716 6 p.

Research output: Contribution to journalArticle

Acid Sensing Ion Channels
Ischemia
Neurons
Acids
Degenerin Sodium Channels
226 Citations (Scopus)

A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1

Keller, D. M., Zeng, X., Wang, Y., Zhang, Q. H., Kapoor, M., Shu, H., Goodman, R., Lozano, G., Zhao, Y. & Lu, H., 2001, In : Molecular Cell. 7, 2, p. 283-292 10 p.

Research output: Contribution to journalArticle

Casein Kinase II
Protein-Serine-Threonine Kinases
Transcriptional Elongation Factors
DNA Damage
Phosphotransferases
355 Citations (Scopus)

A mitochondrial perspective on cell death

Bernardi, P., Petronilli, V., Di Lisa, F. & Forte, M., Feb 1 2001, In : Trends in Biochemical Sciences. 26, 2, p. 112-117 6 p.

Research output: Contribution to journalArticle

Mitochondria
Cell death
Proto-Oncogene Proteins c-bcl-2
Cell Death
Mitochondrial Proteins
375 Citations (Scopus)

Amphetamine, 3,4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace amine receptor

Bunzow, J. R., Sonders, M. S., Arttamangkul, S., Harrison, L. M., Zhang, G., Quigley, D. I., Darland, T., Suchland, K. L., Pasumamula, S., Kennedy, J. L., Olson, S., Magenis, R. E., Amara, S. G. & Grandy, D., 2001, In : Molecular Pharmacology. 60, 6, p. 1181-1188 8 p.

Research output: Contribution to journalArticle

Amphetamines
N-Methyl-3,4-methylenedioxyamphetamine
Lysergic Acid Diethylamide
Amphetamine
Tyramine
98 Citations (Scopus)

Amphetamine selectively blocks inhibitory glutamate transmission in dopamine neurons

Paladini, C. A., Fiorillo, C. D., Morikawa, H. & Williams, J., 2001, In : Nature Neuroscience. 4, 3, p. 275-281 7 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Amphetamine
Glutamic Acid
Dopamine
Metabotropic Glutamate Receptors
85 Citations (Scopus)

Annexin 2 has an essential role in actin-based macropinocytic rocketing

Merrifield, C. J., Rescher, U., Almers, W., Proust, J., Gerke, V., Sechi, A. S. & Moss, S. E., Jul 24 2001, In : Current Biology. 11, 14, p. 1136-1141 6 p.

Research output: Contribution to journalArticle

Annexins
actin
Actins
exocytosis
endocytosis
25 Citations (Scopus)

A RAVE about opioid withdrawal

Alvarez, V., Arttamangkul, S. & Williams, J., Dec 6 2001, In : Neuron. 32, 5, p. 761-763 3 p.

Research output: Contribution to journalArticle

Opioid Receptors
Protein Transport
Morphine
Opioid Analgesics
313 Citations (Scopus)

A real-time view of life within 100 NM of the plasma membrane

Steyer, J. A. & Almers, W., Apr 2001, In : Nature Reviews Molecular Cell Biology. 2, 4, p. 268-275 8 p.

Research output: Contribution to journalArticle

Organelles
Cell Membrane
Transport Vesicles
Fluorescence Microscopy
Proteins
45 Citations (Scopus)

ATOP-dependent Activation of the Intermediate Conductance, Ca 2+-activated K+ Channel, hIK1, is Conferred by a C-terminal Domain

Gerlach, A. C., Syme, C. A., Giltinan, L., Adelman, J. & Devor, D. C., Apr 6 2001, In : Journal of Biological Chemistry. 276, 14, p. 10963-10970 8 p.

Research output: Contribution to journalArticle

Phosphorylation
Chemical activation
Amino Acids
Cyclic AMP-Dependent Protein Kinases
Threonine
7 Citations (Scopus)

Beam me up, Scottie! Trek channels swing both ways

Maylie, J. & Adelman, J., 2001, In : Nature Neuroscience. 4, 5, p. 457-458 2 p.

Research output: Contribution to journalArticle

Tandem Pore Domain Potassium Channels
Cyclic AMP-Dependent Protein Kinases
129 Citations (Scopus)

Biogenesis of porin of the outer mitochondrial membrane involves an import pathway via receptors and the general import pore of the TOM complex

Krimmer, T., Rapaport, D., Ryan, M. T., Meisinger, C., Kassenbrock, C. K., Blachly-Dyson, E., Forte, M., Douglas, M. G., Neupert, W., Nargang, F. E. & Pfanner, N., Jan 22 2001, In : Journal of Cell Biology. 152, 2, p. 289-300 12 p.

Research output: Contribution to journalArticle

Porins
Mitochondrial Membranes
Mitochondria
Voltage-Dependent Anion Channels
Neurospora crassa
647 Citations (Scopus)

Cellular and synaptic adaptations mediating opioid dependence

Williams, J., Christie, M. J. & Manzoni, O., 2001, In : Physiological Reviews. 81, 1, p. 299-343 45 p.

Research output: Contribution to journalArticle

Opioid Analgesics
Opioid Receptors
GTP-Binding Proteins
Street Drugs
Second Messenger Systems
52 Citations (Scopus)

Consensus and Variant cAMP-regulated Enhancers Have Distinct CREB-binding Properties

Craig, J. C., Schumacher, M. A., Mansoor, S. E., Farrens, D., Brennan, R. G. & Goodman, R., Apr 13 2001, In : Journal of Biological Chemistry. 276, 15, p. 11719-11728 10 p.

Research output: Contribution to journalArticle

Cyclic AMP Response Element-Binding Protein
Protein Binding
Dimerization
DNA
Ions
179 Citations (Scopus)

Control of Electrical Activity in Central Neurons by Modulating the Gating of Small Conductance Ca2+-activated K+ Channels

Pedarzani, P., Mosbacher, J., Rivard, A., Cingolani, L. A., Oliver, D., Stocker, M., Adelman, J. & Fakler, B., Mar 30 2001, In : Journal of Biological Chemistry. 276, 13, p. 9762-9769 8 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Neurons
Calmodulin
Small-Conductance Calcium-Activated Potassium Channels
Neurology
9 Citations (Scopus)
Cyclic AMP Response Element Modulator
Cyclic AMP Response Element-Binding Protein
Phosphoenolpyruvate
CCAAT-Enhancer-Binding Proteins
Protein Binding
621 Citations (Scopus)

CREB-binding Protein and p300 in Transcriptional Regulation

Vo, N. & Goodman, R., Apr 27 2001, In : Journal of Biological Chemistry. 276, 17, p. 13505-13508 4 p.

Research output: Contribution to journalArticle

Genetic Transcription
CREB-Binding Protein
Biological Models
Trans-Activators
Interferon-beta
55 Citations (Scopus)
Cyclic AMP Response Element-Binding Protein
Calcium-Calmodulin-Dependent Protein Kinases
Neuronal Plasticity
Depolarization
Response Elements
110 Citations (Scopus)

Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1

Schmitt, J. M. & Stork, P., Jun 2001, In : Molecular and Cellular Biology. 21, 11, p. 3671-3683 13 p.

Research output: Contribution to journalArticle

Monomeric GTP-Binding Proteins
Cyclic AMP
NIH 3T3 Cells
Mitogen-Activated Protein Kinases
Growth
31 Citations (Scopus)

Fusion needs more than SNAREs

Almers, W., Feb 1 2001, In : Nature. 409, 6820, p. 567-568 2 p.

Research output: Contribution to journalArticle

SNARE Proteins
Yeasts
Membranes
24 Citations (Scopus)

Genetic analysis of the Drosophila Gsα gene

Wolfgang, W. J., Hoskote, A., Roberts, I. J. H., Jackson, S. & Forte, M., 2001, In : Genetics. 158, 3, p. 1189-1201 13 p.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinases
Drosophila
Genes
Heterotrimeric GTP-Binding Proteins
Transgenes
188 Citations (Scopus)

Glomerulus-specific synchronization of mitral cells in the olfactory bulb

Schoppa, N. E. & Westbrook, G., Aug 30 2001, In : Neuron. 31, 4, p. 639-651 13 p.

Research output: Contribution to journalArticle

Olfactory Bulb
Glutamic Acid
Autoreceptors
Electric Stimulation
Odorants
243 Citations (Scopus)

Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system

Schaefer, M., Petronczki, M., Dorner, D., Forte, M. & Knoblich, J. A., Oct 19 2001, In : Cell. 107, 2, p. 183-194 12 p.

Research output: Contribution to journalArticle

Asymmetric Cell Division
Heterotrimeric GTP-Binding Proteins
Neurology
Nervous System
Drosophila
31 Citations (Scopus)

Hormonal control of insulin-like growth factor I gene transcription in human osteoblasts: Dual actions of cAMP-dependent protein kinase on CCAAT/enhancer-binding protein δ

Billiard, J., Grewal, S. S., Lukaesko, L., Stork, P. & Rotwein, P., Aug 17 2001, In : Journal of Biological Chemistry. 276, 33, p. 31238-31246 9 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Proteins
Osteoblasts
Transcription
Cyclic AMP-Dependent Protein Kinases
Insulin-Like Growth Factor I
69 Citations (Scopus)

Microscopic kinetics and energetics distinguish GABAA receptor agonists from antagonists

Jones, M. V., Jonas, P., Sahara, Y. & Westbrook, G., 2001, In : Biophysical Journal. 81, 5, p. 2660-2670 11 p.

Research output: Contribution to journalArticle

GABA-A Receptor Agonists
GABA-A Receptor Antagonists
Binding Sites
Ligand-Gated Ion Channels
Competitive Binding
276 Citations (Scopus)

Multivesicular release at climbing fiber-Purkinje cell synapses

Wadiche, J. I. & Jahr, C., Oct 25 2001, In : Neuron. 32, 2, p. 301-313 13 p.

Research output: Contribution to journalArticle

Purkinje Cells
Synapses
Glutamic Acid
AMPA Receptors
Synaptic Vesicles
4 Citations (Scopus)

NMDA receptors turn to another channel for inhibition

Schoppa, N. E. & Westbrook, G., Sep 27 2001, In : Neuron. 31, 6, p. 877-879 3 p.

Research output: Contribution to journalArticle

Large-Conductance Calcium-Activated Potassium Channels
Olfactory Bulb
Glutamate Receptors
N-Methyl-D-Aspartate Receptors
Calcium
4 Citations (Scopus)

Nonisotopic methods for detecting activation of small G proteins

Carey, K. D. & Stork, P., 2001, In : Methods. 345, p. 383-397 15 p.

Research output: Contribution to journalArticle

Monomeric GTP-Binding Proteins
Chemical activation
92 Citations (Scopus)

Paradoxical reduction of synaptic inhibition by vigabatrin

Overstreet, L. S. & Westbrook, G., 2001, In : Journal of Neurophysiology. 86, 2, p. 596-603 8 p.

Research output: Contribution to journalArticle

Vigabatrin
gamma-Aminobutyric Acid
Anticonvulsants
4-Aminobutyrate Transaminase
Inhibitory Postsynaptic Potentials
22 Citations (Scopus)

Small-conductance calcium-activated potassium currents in mouse hyperexcitable denervated skeletal muscle

Neelands, T. R., Herson, P. S., Jacobson, D., Adelman, J. & Maylie, J., Oct 15 2001, In : Journal of Physiology. 536, 2, p. 397-407 11 p.

Research output: Contribution to journalArticle

Tail
Potassium
Skeletal Muscle
Calcium-Activated Potassium Channels
Calcium
50 Citations (Scopus)

Structure and complex transcription pattern of the mouse SK1 KCa channel gene, KCNN1

Shmukler, B. E., Bond, C. T., Wilhelm, S., Bruening-Wright, A., Maylie, J., Adelman, J. & Alper, S. L., Mar 19 2001, In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1518, 1-2, p. 36-46 11 p.

Research output: Contribution to journalArticle

Transcription
Apamin
Exons
Genes
Calmodulin
454 Citations (Scopus)

Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin

Schumacher, M. A., Rivard, A. F., Bächinger, H. P. & Adelman, J., Apr 26 2001, In : Nature. 410, 6832, p. 1120-1124 5 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Calmodulin
Calmodulin-Binding Proteins
EF Hand Motifs
Ion Channels
89 Citations (Scopus)

Structure suggests function: The case for synaptic ribbons as exocytotic nanomachines

Lenzi, D. & Von Gersdorff, H., 2001, In : BioEssays. 23, 9, p. 831-840 10 p.

Research output: Contribution to journalArticle

synapse
Synapses
Capacitance measurement
Electrons
Synaptic Vesicles
68 Citations (Scopus)

Synaptic ribbons: Versatile signal transducers

Von Gersdorff, H., 2001, In : Neuron. 29, 1, p. 7-10 4 p.

Research output: Contribution to journalArticle

Transducers
43 Citations (Scopus)

Tufted cell dendrodendritic inhibition in the olfactory bulb is dependent on NMDA receptor activity

Christie, J. M., Schoppa, N. E. & Westbrook, G., 2001, In : Journal of Neurophysiology. 85, 1, p. 169-173 5 p.

Research output: Contribution to journalArticle

Olfactory Bulb
N-Methyl-D-Aspartate Receptors
Interneurons
2-Amino-5-phosphonovalerate
Quinoxalines
2000
102 Citations (Scopus)

Acetylation of adenovirus E1A regulates binding of the transcriptional corepressor CtBP

Zhang, Q., Yao, H., Vo, N. & Goodman, R., Dec 19 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 26, p. 14323-14328 6 p.

Research output: Contribution to journalArticle

Co-Repressor Proteins
Acetylation
Adenoviridae
Carrier Proteins
Protein Binding
1 Citation (Scopus)

An orphan glutamate channel points the way to the gates

Krupp, J. J. & Westbrook, G., Apr 2000, In : Nature Neuroscience. 3, 4, p. 301-302 2 p.

Research output: Contribution to journalArticle

Ion Channel Gating
Kainic Acid Receptors
AMPA Receptors
N-Methyl-D-Aspartate Receptors
Glutamic Acid
59 Citations (Scopus)

Binding and internalization of fluorescent opioid peptide conjugates in living cells

Arttamangkul, S., Alvarez-Maubecin, V., Thomas, G., Williams, J. & Grandy, D., 2000, In : Molecular Pharmacology. 58, 6, p. 1570-1580 11 p.

Research output: Contribution to journalArticle

Opioid Peptides
Opioid Receptors
Ligands
Naloxone
Locus Coeruleus
138 Citations (Scopus)

Biochemical and genetic analysis of the mitochondrial response of yeast to BAX and BCL-X(L)

Gross, A., Pilcher, K., Blachly-Dyson, E., Basso, E., Jockel, J., Bassik, M. C., Korsmeyer, S. J. & Forte, M., May 2000, In : Molecular and Cellular Biology. 20, 9, p. 3125-3136 12 p.

Research output: Contribution to journalArticle

Molecular Biology
Yeasts
Voltage-Dependent Anion Channels
Mitochondrial Genome
Cytochromes c
112 Citations (Scopus)

Calcium and cAMP signals differentially regulate cAMP-responsive element-binding protein function via a Rap-1-extracellular signal-regulated kinase pathway

Grewal, S. S., Fass, D. M., Yao, H., Ellig, C. L., Goodman, R. & Stork, P., Nov 3 2000, In : Journal of Biological Chemistry. 275, 44, p. 34433-34441 9 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 3
Carrier Proteins
Calcium
Extracellular Signal-Regulated MAP Kinases
Cyclic AMP-Dependent Protein Kinases
1272 Citations (Scopus)

CBP/p300 in cell growth, transformation, and development

Goodman, R. & Smolik, S., Jul 1 2000, In : Genes and Development. 14, 13, p. 1553-1577 25 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Embryonic and Fetal Development
Amino Acid Sequence Homology
Oncogenic Viruses
DNA Viruses
67 Citations (Scopus)

CD28 and the tyrosine kinase Lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1

Carey, K. D., Dillon, T. J., Schmitt, J. M., Baird, A. M., Holdorf, A. D., Straus, D. B., Shaw, A. S. & Stork, P., 2000, In : Molecular and Cellular Biology. 20, 22, p. 8409-8419 11 p.

Research output: Contribution to journalArticle

Monomeric GTP-Binding Proteins
Extracellular Signal-Regulated MAP Kinases
T-Cell Antigen Receptor
Mitogen-Activated Protein Kinases
Protein-Tyrosine Kinases
10 Citations (Scopus)

ChIPping away at potassium channel regulation

Li, M. & Adelman, J., Mar 2000, In : Nature Neuroscience. 3, 3, p. 202-204 3 p.

Research output: Contribution to journalArticle

Calcium-Binding Proteins
Potassium Channels
72 Citations (Scopus)

Cholinergic inhibition of ventral midbrain dopamine neurons

Fiorillo, C. D. & Williams, J., Oct 15 2000, In : Journal of Neuroscience. 20, 20, p. 7855-7860 6 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Muscarinic Receptors
Mesencephalon
Cholinergic Agents
Potassium
25 Citations (Scopus)

Cubitus interruptus requires Drosophila CREB-binding protein to activate wingless expression in the Drosophila embryo

Chen, Y., Goodman, R. & Smolik, S. M., Mar 2000, In : Molecular and Cellular Biology. 20, 5, p. 1616-1625 10 p.

Research output: Contribution to journalArticle

CREB-Binding Protein
Drosophila Proteins
Transcriptional Activation
Drosophila
Hedgehogs
167 Citations (Scopus)

Ectopic g-protein expression in dopamine and serotonin neurons blocks cocaine sensitization in Drosophila melanogaster

Li, H., Chaney, S., Forte, M. & Hirsh, J., Feb 1 2000, In : Current Biology. 10, 4, p. 211-214 4 p.

Research output: Contribution to journalArticle

cocaine
Dopaminergic Neurons
Drosophila melanogaster
dopamine
Cocaine
62 Citations (Scopus)

Fast NMDA receptor-mediated synaptic currents in neurons from mice lacking the ε2 (NR2B) subunit

Tovar, K. R., Sprouffske, K. & Westbrook, G., 2000, In : Journal of Neurophysiology. 83, 1, p. 616-620 5 p.

Research output: Contribution to journalArticle

N-Methyl-D-Aspartate Receptors
Neurons
Excitatory Postsynaptic Potentials
Membranes
Synapses
350 Citations (Scopus)
Neuronal Plasticity
Synapses
Sound Localization
Aptitude
AMPA Receptors
261 Citations (Scopus)

Functional coupling between neurons and glia

Alvarez-Maubecin, V., García-Hernández, F., Williams, J. & Van Bockstaele, E. J., Jun 1 2000, In : Journal of Neuroscience. 20, 11, p. 4091-4098 8 p.

Research output: Contribution to journalArticle

Neuroglia
Neurons
Locus Coeruleus
Connexins
Gap Junctions