Vaccine and Gene Therapy Institute

Research Output

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Review article
2019

Casting a wider net: Immunosurveillance by nonclassical MHC molecules

D’Souza, M. P., Adams, E., Altman, J. D., Birnbaum, M. E., Boggiano, C., Casorati, G., Chien, Y. H., Conley, A., Eckle, S. B. G., Früh, K., Gondré-Lewis, T., Hassan, N., Huang, H., Jayashankar, L., Kasmar, A. G., Kunwar, N., Lavelle, J., Lewinsohn, D. M., Moody, B., Picker, L. & 5 others, Ramachandra, L., Shastri, N., Parham, P., McMichael, A. J. & Yewdell, J. W., Feb 2019, In : PLoS pathogens. 15, 2, e1007567.

Research output: Contribution to journalReview article

Open Access
11 Scopus citations
2018

HCMV miRNA targets reveal important cellular pathways for viral replication, latency, and reactivation

Diggins, N. L. & Hancock, M. H., Oct 22 2018, In : Non-coding RNA. 4, 4, 29.

Research output: Contribution to journalReview article

7 Scopus citations

Malaria Vaccines: Recent Advances and New Horizons

Draper, S. J., Sack, B. K., King, C. R., Nielsen, C. M., Rayner, J. C., Higgins, M. K., Long, C. A. & Seder, R. A., Jul 11 2018, In : Cell Host and Microbe. 24, 1, p. 43-56 14 p.

Research output: Contribution to journalReview article

Open Access
68 Scopus citations

Next-generation in Situ Hybridization Approaches to Define and Quantify HIV and SIV Reservoirs in Tissue Microenvironments

Deleage, C., Chan, C. N., Busman-Sahay, K. & Estes, J. D., Jan 9 2018, In : Retrovirology. 15, 1, 4.

Research output: Contribution to journalReview article

18 Scopus citations

Nonhuman primate models of human viral infections

Estes, J. D., Wong, S. W. & Brenchley, J. M., Jun 1 2018, In : Nature Reviews Immunology. 18, 6, p. 390-404 15 p.

Research output: Contribution to journalReview article

22 Scopus citations

Visualizing the immune system: Providing key insights into HIV/SIV infections

Estes, J. D., LeGrand, R. & Petrovas, C., Mar 2 2018, In : Frontiers in immunology. 9, MAR, 423.

Research output: Contribution to journalReview article

6 Scopus citations
2017
35 Scopus citations

Unusual antigen presentation offers new insight into HIV vaccine design

McMichael, A. J. & Picker, L. J., Jun 1 2017, In : Current opinion in immunology. 46, p. 75-81 7 p.

Research output: Contribution to journalReview article

7 Scopus citations
2016

An expanding toolkit for preclinical pre-erythrocytic malaria vaccine development: Bridging traditional mouse malaria models and human trials

Steel, R. W. J., Kappe, S. H. I. & Sack, B. K., Dec 2016, In : Future Microbiology. 11, 12, p. 1563-1579 17 p.

Research output: Contribution to journalReview article

4 Scopus citations

Imaging lymphoid tissues in nonhuman primates to understand SIV pathogenesis and persistence

Deleage, C., Turkbey, B. & Estes, J. D., Aug 1 2016, In : Current Opinion in Virology. 19, p. 77-84 8 p.

Research output: Contribution to journalReview article

14 Scopus citations

Novel Imaging Methods for Analysis of Tissue Resident Cells in HIV/SIV

Moysi, E., Estes, J. D. & Petrovas, C., Feb 1 2016, In : Current HIV/AIDS Reports. 13, 1, p. 38-43 6 p.

Research output: Contribution to journalReview article

4 Scopus citations

Strategies to target non-T-cell HIV reservoirs

Sacha, J. B. & Ndhlovu, L. C., Jul 1 2016, In : Current Opinion in HIV and AIDS. 11, 4, p. 376-382 7 p.

Research output: Contribution to journalReview article

8 Scopus citations
2015

Humanized mouse models of human cytomegalovirus infection

Crawford, L. B., Streblow, D. N., Hakki, M., Nelson, J. A. & Caposio, P., Jun 29 2015, In : Current Opinion in Virology. 13, p. 86-92 7 p.

Research output: Contribution to journalReview article

27 Scopus citations

Nonhuman primate models of chikungunya virus infection and disease (CHIKV NHP model)

Broeckel, R., Haese, N., Messaoudi, I. & Streblow, D. N., Sep 16 2015, In : Pathogens. 4, 3, p. 662-681 20 p.

Research output: Contribution to journalReview article

20 Scopus citations

Viral Inhibition of the Transporter Associated with Antigen Processing (TAP): A Striking Example of Functional Convergent Evolution

Verweij, M. C., Horst, D., Griffin, B. D., Luteijn, R. D., Davison, A. J., Ressing, M. E. & Wiertz, E. J. H. J., Apr 1 2015, In : PLoS pathogens. 11, 4, e1004743.

Research output: Contribution to journalReview article

37 Scopus citations
2014

Cytomegalovirus microRNAs

Hook, L., Hancock, M., Landais, I., Grabski, R., Britt, W. & Nelson, J. A., Aug 2014, In : Current Opinion in Virology. 7, 1, p. 40-46 7 p.

Research output: Contribution to journalReview article

40 Scopus citations

Development of gene transfer for induction of antigen-specific tolerance

Sack, B. K., Herzog, R. W., Terhorst, C. & Markusic, D. M., Jan 8 2014, In : Molecular Therapy - Methods and Clinical Development. 1, p. 14013 1 p., 14013.

Research output: Contribution to journalReview article

Open Access
48 Scopus citations

Novel vaccine vectors for HIV.1

Barouch, D. H. & Picker, L. J., Jan 1 2014, In : Nature Reviews Microbiology. 12, 11, p. 765-771 7 p.

Research output: Contribution to journalReview article

58 Scopus citations
2013

Cytomegalovirus vectors violate CD8+ T cell epitope recognition paradigms

Hansen, S. G., Sacha, J. B., Hughes, C. M., Ford, J. C., Burwitz, B. J., Scholz, I., Gilbride, R. M., Lewis, M. S., Gilliam, A. N., Ventura, A. B., Malouli, D., Xu, G., Richards, R., Whizin, N., Reed, J. S., Hammond, K. B., Fischer, M., Turner, J. M., Legasse, A. W., Axthelm, M. K. & 5 others, Edlefsen, P. T., Nelson, J. A., Lifson, J. D., Früh, K. & Picker, L. J., 2013, In : Science. 340, 6135, 1237874.

Research output: Contribution to journalReview article

291 Scopus citations

Development of replication-competent viral vectors for HIV vaccine delivery

Parks, C. L., Picker, L. J. & King, C. R., Sep 2013, In : Current Opinion in HIV and AIDS. 8, 5, p. 402-411 10 p.

Research output: Contribution to journalReview article

41 Scopus citations

Evasion of adaptive and innate immune response mechanisms by γ-herpesviruses

Feng, P., Moses, A. & Früh, K., Jun 2013, In : Current Opinion in Virology. 3, 3, p. 285-295 11 p.

Research output: Contribution to journalReview article

15 Scopus citations

Functional genomics approaches to understand cytomegalovirus replication, latency and pathogenesis

Landais, I. & Nelson, J. A., 2013, In : Current Opinion in Virology. 3, 4, p. 408-415 8 p.

Research output: Contribution to journalReview article

12 Scopus citations

Rhesus macaque rhadinovirus-associated disease

Estep, R. D. & Wong, S. W., Jun 2013, In : Current Opinion in Virology. 3, 3, p. 245-250 6 p.

Research output: Contribution to journalReview article

12 Scopus citations

Roadblocks to translational challenges on viral pathogenesis

Deeks, S., Drosten, C., Picker, L., Subbarao, K. & Suzich, J., Jan 2013, In : Nature medicine. 19, 1, p. 30-34 5 p.

Research output: Contribution to journalReview article

6 Scopus citations

The inflammasome as a target of modulation by DNA viruses

Amsler, L., Malouli, D. & Defilippis, V., 2013, In : Future Virology. 8, 4, p. 357-370 14 p.

Research output: Contribution to journalReview article

4 Scopus citations

The tiers and dimensions of evasion of the type i interferon response by human cytomegalovirus

Amsler, L., Verweij, M. C. & Defilippis, V. R., Dec 13 2013, In : Journal of molecular biology. 425, 24, p. 4857-4871 15 p.

Research output: Contribution to journalReview article

40 Scopus citations
2012

[Protective immune responses against HIV/SIV by live attenuated vaccine in non-human primate models].

Fukazawa, Y., 2012, In : Uirusu. 62, 2, p. 167-174 8 p.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

New paradigms for HIV/AIDS vaccine development

Picker, L. J., Hansen, S. G. & Lifson, J. D., 2012, In : Annual review of medicine. 63, p. 95-111 17 p.

Research output: Contribution to journalReview article

100 Scopus citations
2011

Barriers to mucosal transmission of immunodeficiency viruses

Keele, B. F. & Estes, J. D., Jul 28 2011, In : Blood. 118, 4, p. 839-846 8 p.

Research output: Contribution to journalReview article

57 Scopus citations

Nonhuman primate models of human immunology

Messaoudi, I., Estep, R., Robinson, B. & Wong, S. W., Jan 15 2011, In : Antioxidants and Redox Signaling. 14, 2, p. 261-273 13 p.

Research output: Contribution to journalReview article

68 Scopus citations

Viral evasion of T cell immunity: Ancient mechanisms offering new applications

Horst, D., Verweij, M. C., Davison, A. J., Ressing, M. E. & Wiertz, E. J. H. J., Feb 1 2011, In : Current opinion in immunology. 23, 1, p. 96-103 8 p.

Research output: Contribution to journalReview article

64 Scopus citations

Viral takeover of the host ubiquitin system

Gustin, J. K., Moses, A. V., Früh, K. & Douglas, J. L., 2011, In : Frontiers in Microbiology. 2, JULY

Research output: Contribution to journalReview article

32 Scopus citations
2010

Herpesviruses and immunity: The art of evasion

Griffin, B. D., Verweij, M. C. & Wiertz, E. J. H. J., Jun 1 2010, In : Veterinary Microbiology. 143, 1, p. 89-100 12 p.

Research output: Contribution to journalReview article

72 Scopus citations

Simian herpesviruses and their risk to humans

Estep, R. D., Messaoudi, I. & Wong, S. W., May 26 2010, In : Vaccine. 28, SUPPL. 2, p. B78-B84

Research output: Contribution to journalReview article

19 Scopus citations

The great escape: Viral strategies to counter BST-2/ tetherin

Douglas, J. L., Gustin, J. K., Viswanathan, K., Mansouri, M., Moses, A. V. & Früh, K., May 2010, In : PLoS pathogens. 6, 5, p. 1-12 12 p.

Research output: Contribution to journalReview article

96 Scopus citations

The use of RNAi-based screens to identify host proteins involved in viral replication

Hirsch, A. J., Feb 2010, In : Future Microbiology. 5, 2, p. 303-311 9 p.

Research output: Contribution to journalReview article

45 Scopus citations

Viral hijacking of the host ubiquitin system to evade interferon responses

Viswanathan, K., Früh, K. & DeFilippis, V., Aug 2010, In : Current Opinion in Microbiology. 13, 4, p. 517-523 7 p.

Research output: Contribution to journalReview article

44 Scopus citations

Viruses, microRNAs, and host interactions

Skalsky, R. L. & Cullen, B. R., Oct 13 2010, In : Annual Review of Microbiology. 64, p. 123-141 19 p.

Research output: Contribution to journalReview article

432 Scopus citations
2009

Evading the immune response upon in vivo gene therapy with viral vectors

Sack, B. K. & Herzog, R. W., Oct 2009, In : Current Opinion in Molecular Therapeutics. 11, 5, p. 493-503 11 p.

Research output: Contribution to journalReview article

40 Scopus citations

IL-2, IL-7 and IL-15 as immuno-modulators during SIV/HIV vaccination and treatment

Leone, A., Picker, L. J. & Sodora, D. L., May 26 2009, In : Current HIV Research. 7, 1, p. 83-90 8 p.

Research output: Contribution to journalReview article

42 Scopus citations

Multifaceted evasion of the interferon response by cytomegalovirus

Marshall, E. E. & Geballe, A. P., Sep 1 2009, In : Journal of Interferon and Cytokine Research. 29, 9, p. 609-619 11 p.

Research output: Contribution to journalReview article

50 Scopus citations

Pirate primates in uncharted waters: Lymphocyte transfers in unrelated, MHC-matched macaques

Burwitz, B. J., Greene, J. M. & O'Connor, D. H., 2009, In : Current HIV Research. 7, 1, p. 51-56 6 p.

Research output: Contribution to journalReview article

3 Scopus citations

Role of collagen deposition in lymphatic tissues and immune reconstruction during HIV-1 and SIV infections

Estes, J. D., Feb 1 2009, In : Current HIV/AIDS Reports. 6, 1, p. 29-35 7 p.

Research output: Contribution to journalReview article

15 Scopus citations

Toward an AIDS vaccine: Lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts

Sodora, D. L., Allan, J. S., Apetrei, C., Brenchley, J. M., Douek, D. C., Else, J. G., Estes, J. D., Hahn, B. H., Hirsch, V. M., Kaur, A., Kirchhoff, F., Muller-Trutwin, M., Pandrea, I., Schmitz, J. E. & Silvestri, G., Aug 2009, In : Nature medicine. 15, 8, p. 861-865 5 p.

Research output: Contribution to journalReview article

167 Scopus citations
2008

Pathogenic mechanisms in simian immunodeficiency virus infection

Grossman, Z. & Picker, L. J., May 1 2008, In : Current Opinion in HIV and AIDS. 3, 3, p. 380-386 7 p.

Research output: Contribution to journalReview article

17 Scopus citations

Rhesus CMV: An emerging animal model for human CMV

Powers, C. & Früh, K., Jun 2008, In : Medical Microbiology and Immunology. 197, 2, p. 109-115 7 p.

Research output: Contribution to journalReview article

69 Scopus citations

The functions of herpesvirus-encoded microRNAs

Grey, F., Hook, L. & Nelson, J., Jun 2008, In : Medical Microbiology and Immunology. 197, 2, p. 261-267 7 p.

Research output: Contribution to journalReview article

52 Scopus citations
66 Scopus citations
2007

Acceleration of allograft failure by cytomegalovirus

Streblow, D. N., Orloff, S. L. & Nelson, J. A., Oct 2007, In : Current opinion in immunology. 19, 5, p. 577-582 6 p.

Research output: Contribution to journalReview article

92 Scopus citations