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2010

Differential in vivo effects on target pathways of a novel arylpyrazole glucocorticoid receptor modulator compared with prednisolone

Roohk, D. J., Varady, K. A., Turner, S. M., Emson, C. L., Gelling, R. W., Shankaran, M., Lindwall, G., Shipp, L. E., Scanlan, T. S., Wang, J. C. & Hellerstein, M. K., Apr 1 2010, In : Journal of Pharmacology and Experimental Therapeutics. 333, 1, p. 281-289 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Differential localization of vesicular glutamate transporters and peptides in corneal afferents to trigeminal nucleus caudalis

Hegarty, D. M., Tonsfeldt, K., Hermes, S. M., Helfand, H. & Aicher, S. A., Sep 1 2010, In : Journal of Comparative Neurology. 518, 17, p. 3557-3569 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice

Lee, C. R., Imig, J. D., Edin, M. L., Foley, J., DeGraff, L. M., Bradbury, J. A., Graves, J. P., Lih, F. B., Clark, J., Myers, P., Perrow, A. L., Lepp, A. N., Kannon, M. A., Ronnekleiv, O. K., Alkayed, N. J., Falck, J. R., Tomer, K. B. & Zeldin, D. C., Oct 2010, In : FASEB Journal. 24, 10, p. 3770-3781 12 p.

Research output: Contribution to journalArticle

107 Scopus citations

ESI-MS/MS quantification of 7α-hydroxy-4-cholesten-3-one facilitates rapid, convenient diagnostic testing for cerebrotendinous xanthomatosis

DeBarber, A. E., Connor, W. E., Pappu, A. S., Merkens, L. S. & Steiner, R. D., Jan 4 2010, In : Clinica Chimica Acta. 411, 1-2, p. 43-48 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Excessive Na+/H+ exchange in disruption of dendritic Na+and Ca2+ homeostasis and mitochondrial dysfunction following in vitro ischemia

Kintner, D. B., Chen, X., Currie, J., Chanana, V., Ferrazzano, P., Baba, A., Matsuda, T., Cohen, M., Orlowski, J., Chiu, S. Y., Taunton, J. & Sun, D., Nov 5 2010, In : Journal of Biological Chemistry. 285, 45, p. 35155-35168 14 p.

Research output: Contribution to journalArticle

11 Scopus citations
34 Scopus citations

Hypomorphic temperature-sensitive alleles of NSDHL cause CK syndrome

McLarren, K. W., Severson, T. M., Du Souich, C., Stockton, D. W., Kratz, L. E., Cunningham, D., Hendson, G., Morin, R. D., Wu, D., Paul, J. E., An, J., Nelson, T. N., Chou, A., Debarber, A. E., Merkens, L. S., Michaud, J. L., Waters, P. J., Yin, J., McGillivray, B., Demos, M. & 20 others, Rouleau, G. A., Grzeschik, K. H., Smith, R., Tarpey, P. S., Shears, D., Schwartz, C. E., Gecz, J., Stratton, M. R., Arbour, L., Hurlburt, J., Van Allen, M. I., Herman, G. E., Zhao, Y., Moore, R., Kelley, R. I., Jones, S. J. M., Steiner, R. D., Raymond, F. L., Marra, M. A. & Boerkoel, C. F., Dec 10 2010, In : American Journal of Human Genetics. 87, 6, p. 905-914 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

Imaging lipids in living cells

Schultz, C., Neef, A. B., Gadella, T. W. & Goedhart, J., Jul 1 2010, In : Cold Spring Harbor Protocols. 5, 7

Research output: Contribution to journalArticle

16 Scopus citations

Infarction-induced cytokines cause local depletion of tyrosine hydroxylase in cardiac sympathetic nerves: Experimental Physiology-Research Paper

Parrish, D. C., Alston, E. N., Rohrer, H., Nkadi, P., Woodward, W. R., Schütz, G. & Habecker, B. A., Feb 2010, In : Experimental physiology. 95, 2, p. 304-314 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Labeling lipids for imaging in fixed cells

Schultz, C., Neef, A. B., Gadella, T. W. & Goedhart, J., Jul 1 2010, In : Cold Spring Harbor Protocols. 5, 7

Research output: Contribution to journalArticle

7 Scopus citations

Labeling lipids for imaging in live cells

Schultz, C., Neef, A. B., Gadella, T. W. & Goedhart, J., Jul 1 2010, In : Cold Spring Harbor Protocols. 5, 7

Research output: Contribution to journalArticle

3 Scopus citations

Leptin excites proopiomelanocortin neurons via activation of TRPC channels

Qiu, J., Fang, Y., Rønnekleiv, O. K. & Kelly, M. J., Jan 27 2010, In : Journal of Neuroscience. 30, 4, p. 1560-1565 6 p.

Research output: Contribution to journalArticle

124 Scopus citations

Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors

Powell, C. L., Bradford, B. U., Craig, C. P., Tsuchiya, M., Uehara, T., O'Connell, T. M., Pogribny, I. P., Melnyk, S., Koop, D. R., Bleyle, L., Threadgill, D. W. & Rusyn, I., May 1 2010, In : Toxicological Sciences. 115, 1, p. 131-139 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Normal thermoregulatory responses to 3-iodothyronamine, trace amines and amphetamine-like psychostimulants in trace amine associated receptor 1 knockout mice

Panas, H. N., Lynch, L. J., Vallender, E. J., Xie, Z., Chen, G. L., Lynn, S. K., Scanlan, T. S. & Miller, G. M., Jul 1 2010, In : Journal of Neuroscience Research. 88, 9, p. 1962-1969 8 p.

Research output: Contribution to journalArticle

59 Scopus citations

Opioid receptor internalization contributes to dermorphin-mediated antinociception

Macey, T. A., Ingram, S. L., Bobeck, E. N., Hegarty, D. M., Aicher, S. A., Arttamangkul, S. & Morgan, M. M., Jun 1 2010, In : Neuroscience. 168, 2, p. 543-550 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Optical tracking of phenotypically diverse individual synapses on solitary tract nucleus neurons

Jin, Y. H., Cahill, E. A., Fernandes, L. G., Wang, X., Chen, W., Smith, S. M. & Andresen, M. C., Feb 2 2010, In : Brain research. 1312, p. 54-66 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

Pharmacokinetic study of acid in multiple sclerosis: Comparing mice and human pharmacokinetic parameters

Yadav, V., Marracci, G. H., Munar, M. Y., Cherala, G., Stuber, L. E., Alvarez, L., Shinto, L., Koop, D. R. & Bourdette, D. N., Apr 1 2010, In : Multiple Sclerosis. 16, 4, p. 387-397 11 p.

Research output: Contribution to journalArticle

37 Scopus citations

Polybrominated diphenyl ethers induce developmental neurotoxicity in a human in vitro model: Evidence for endocrine disruption

Schreiber, T., Gassmann, K., Götz, C., Hübenthal, U., Moors, M., Krause, G., Merk, H. F., Nguyen, N. H., Scanlan, T. S., Abel, J., Rose, C. R. & Fritsche, E., Apr 1 2010, In : Environmental health perspectives. 118, 4, p. 572-578 7 p.

Research output: Contribution to journalArticle

135 Scopus citations

Pregnancy impairs baroreflex control of heart rate in rats: Role of insulin sensitivity

Brooks, V. L., Mulvaney, J. M., Azar, A. S., Zhao, D. & Goldman, R. K., Feb 1 2010, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 298, 2, p. R419-R426

Research output: Contribution to journalArticle

16 Scopus citations

Prenatal exposure to vinclozolin disrupts selective aspects of the gonadotrophin-releasing hormone neuronal system of the rabbit

Wadas, B. C., Hartshorn, C. A., Aurand, E. R., Palmer, J. S., Roselli, C. E., Noel, M. L., Gore, A. C., Veeramachaneni, D. N. R. & Tobet, S. A., Jun 2010, In : Journal of Neuroendocrinology. 22, 6, p. 518-526 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Primary Afferent Activation of Thermosensitive TRPV1 Triggers Asynchronous Glutamate Release at Central Neurons

Peters, J. H., McDougall, S. J., Fawley, J. A., Smith, S. M. & Andresen, M. C., Mar 11 2010, In : Neuron. 65, 5, p. 657-669 13 p.

Research output: Contribution to journalArticle

121 Scopus citations

R9AP stabilizes RGS11-Gβ5 and accelerates the early light response of ON-bipolar cells

Jeffrey, B. G., Morgans, C. W., Puthussery, T., Wensel, T. G., Burke, N. S., Brown, R. L. & Duvoisin, R. M., Mar 1 2010, In : Visual neuroscience. 27, 1-2, p. 9-17 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

RGS7 and -11 complexes accelerate the ON-bipolar cell light response

Zhang, J., Jeffrey, B. G., Morgans, C. W., Burke, N. S., Haley, T. L., Duvoisin, R. M. & Lane Brown, R., Feb 1 2010, In : Investigative Ophthalmology and Visual Science. 51, 2, p. 1121-1129 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Roles of estrogen receptors alpha and beta in sexually dimorphic neuroprotection against glutamate toxicity

Bryant, D. N. & Dorsa, D. M., Nov 1 2010, In : Neuroscience. 170, 4, p. 1261-1269 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

RSK-mediated phosphorylation in the C/EBPβ leucine zipper regulates DNA binding, dimerization, and growth arrest activity

Lee, S., Shuman, J. D., Guszczynski, T., Sakchaisri, K., Sebastian, T., Copeland, T. D., Miller, M., Cohen, M. S., Taunton, J., Smart, R. C., Xiao, Z., Yu, L. R., Veenstra, T. D. & Johnson, P. F., Jun 1 2010, In : Molecular and cellular biology. 30, 11, p. 2621-2635 15 p.

Research output: Contribution to journalArticle

43 Scopus citations

Selective activation of mGluR8 receptors modulates retinal ganglion cell light responses

Quraishi, S., Reed, B. T., Duvoisin, R. M. & Taylor, W. R., Mar 31 2010, In : Neuroscience. 166, 3, p. 935-941 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Semisynthesis of NaK, a Na+ and K+ conducting ion channel

Linn, K. M., Derebe, M. G., Jiang, Y. & Valiyaveetil, F. I., Jun 1 2010, In : Biochemistry. 49, 21, p. 4450-4456 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Sex-dependent cognitive phenotype of mice lacking mGluR8

Duvoisin, R. M., Villasana, L., Pfankuch, T. & Raber, J., May 1 2010, In : Behavioural Brain Research. 209, 1, p. 21-26 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Studies of ion channels using expressed protein ligation

Focke, P. J. & Valiyaveetil, F. I., Dec 1 2010, In : Current Opinion in Chemical Biology. 14, 6, p. 797-802 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Targeting CREB for cancer therapy: Friend or foe

Xiao, X., Li, B. X., Mitton, B., Ikeda, A. & Sakamoto, K. M., Jun 23 2010, In : Current Cancer Drug Targets. 10, 4, p. 384-391 8 p.

Research output: Contribution to journalArticle

88 Scopus citations

The effects of sterol structure upon sterol esterification

Lin, D. S., Steiner, R. D., Merkens, L. S., Pappu, A. S. & Connor, W. E., Jan 1 2010, In : Atherosclerosis. 208, 1, p. 155-160 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

The ovine sexually dimorphic nucleus, aromatase, and sexual partner preferences in sheep

Roselli, C. E. & Stormshak, F., Feb 28 2010, In : Journal of Steroid Biochemistry and Molecular Biology. 118, 4-5, p. 252-256 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

Thermally active TRPV1 tonically drives central spontaneous glutamate release

Shoudai, K., Peters, J. H., McDougall, S. J., Fawley, J. A. & Andresen, M. C., Oct 27 2010, In : Journal of Neuroscience. 30, 43, p. 14470-14475 6 p.

Research output: Contribution to journalArticle

76 Scopus citations

The T3 receptor β1 isoform regulates UCP1 and D2 deiodinase in rat brown adipocytes

Martinez De Mena, R., Scanlan, T. S. & Obregon, M. J., Oct 1 2010, In : Endocrinology. 151, 10, p. 5074-5083 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

The TRβ-selective agonist, GC-1, stimulates mitochondrial oxidative processes to a lesser extent than triiodothyronine

Venditti, P., Chiellini, G., Di Stefano, L., Napolitano, G., Zucchi, R., Columbano, A., Scanlan, T. S. & Di Meo, S., Jun 1 2010, In : Journal of Endocrinology. 205, 3, p. 279-289 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Tissue distribution and cardiac metabolism of 3-iodothyronamine

Saba, A., Chiellini, G., Frascarelli, S., Marchini, M., Ghelardoni, S., Raffaelli, A., Tonacchera, M., Vitti, P., Scanlan, T. S. & Zucchi, R., Oct 2010, In : Endocrinology. 151, 10, p. 5063-5073 11 p.

Research output: Contribution to journalArticle

86 Scopus citations

Transfection of cells with DNA encoding a visible fluorescent protein-tagged lipid-binding domain

Schultz, C., Neef, A. B., Gadella, T. W. & Goedhart, J., Jul 1 2010, In : Cold Spring Harbor Protocols. 5, 7

Research output: Contribution to journalArticle

3 Scopus citations

Transport of thyroid hormones is selectively inhibited by 3-iodothyronamine

Ianculescu, A. G., Friesema, E. C. H., Visser, T. J., Giacomini, K. M. & Scanlan, T. S., Aug 1 2010, In : Molecular BioSystems. 6, 8, p. 1403-1410 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
2009

17beta;-estradiol regulation of T-type calcium channels in gonadotropin-releasing hormone neurons

Zhang, C., Bosch, M. A., Rick, E. A., Kelly, M. J. & Rønnekleiv, O. K., Aug 26 2009, In : Journal of Neuroscience. 29, 34, p. 10552-10562 11 p.

Research output: Contribution to journalArticle

71 Scopus citations
31 Scopus citations

Absence of gp130 in dopamine β-hydroxylase-expressing neurons leads to autonomic imbalance and increased reperfusion arrhythmias

Parrish, D. C., Alston, E. N., Rohrer, H., Hermes, S. M., Aicher, S. A., Nkadi, P., Woodward, W. R., Stubbusch, J., Gardner, R. T. & Habecker, B. A., Sep 1 2009, In : American Journal of Physiology - Heart and Circulatory Physiology. 297, 3, p. H960-H967

Research output: Contribution to journalArticle

11 Scopus citations

Age-dependent effects of testosterone in experimental stroke

Cheng, J., Hu, W., Toung, T. J., Zhang, Z., Parker, S. M., Roselli, C. E. & Hurn, P. D., Jan 1 2009, In : Journal of Cerebral Blood Flow and Metabolism. 29, 3, p. 486-494 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Baroreflex sensitivity varies during the rat estrous cycle: Role of gonadal steroids

Goldman, R. K., Azar, A. S., Mulvaney, J. M., Hinojosa-Laborde, C., Haywood, J. R. & Brooks, V. L., May 1 2009, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 296, 5, p. R1419-R1426

Research output: Contribution to journalArticle

36 Scopus citations

Central effects of thyronamines on glucose metabolism in rats

Klieverik, L. P., Foppen, E., Ackermans, M. T., Serlie, M. J., Sauerwein, H. P., Scanlan, T. S., Grandy, D. K., Fliers, E. & Kalsbeek, A., Aug 5 2009, In : Journal of Endocrinology. 201, 3, p. 377-386 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

Chemical biologists gather in Heidelberg

Köhn, M. & Schultz, C., Feb 6 2009, In : Nature Chemical Biology. 5, 2, p. 66-69 4 p.

Research output: Contribution to journalArticle

Convergence of cranial visceral afferents within the solitary tract nucleus

McDougall, S. J., Peters, J. H. & Andresen, M. C., Oct 14 2009, In : Journal of Neuroscience. 29, 41, p. 12886-12895 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Cross-talk between membrane-initiated and nuclear-initiated oestrogen signalling in the hypothalamus

Roepke, T. A., Qiu, J., Bosch, M. A., Rønnekleiv, O. K. & Kelly, M. J., Apr 9 2009, In : Journal of Neuroendocrinology. 21, 4, p. 263-270 8 p.

Research output: Contribution to journalArticle

62 Scopus citations

Curcumin blocks CCL2-induced adhesion, motility and invasion, in part, through down-regulation of CCL2 expression and proteolytic activity

Herman, J. G., Stadelman, H. L. & Roselli, C. E., Jul 6 2009, In : International Journal of Oncology. 34, 5, p. 1319-1327 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

Cystic fibrosis transmembrane conductance regulator: Using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore

Alexander, C., Ivetac, A., Liu, X., Norimatsu, Y., Serrano, J. R., Landstrom, A., Sansom, M. & Dawson, D. C., Oct 27 2009, In : Biochemistry. 48, 42, p. 10078-10088 11 p.

Research output: Contribution to journalArticle

62 Scopus citations

Differential effects of TR ligands on hormone dissociation rates: Evidence for multiple ligand entry/exit pathways

Cunha Lima, S. T., Nguyen, N. H., Togashi, M., Apriletti, J. W., Nguyen, P., Polikarpov, I., Scanlan, T. S., Baxter, J. D. & Webb, P., Nov 1 2009, In : Journal of Steroid Biochemistry and Molecular Biology. 117, 4-5, p. 125-131 7 p.

Research output: Contribution to journalArticle

5 Scopus citations