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2012

Target-activated prodrugs (TAPs) for the autoregulated inhibition of MMP12

Cobos-Correa, A., Stein, F. & Schultz, C., Aug 9 2012, In : ACS Medicinal Chemistry Letters. 3, 8, p. 653-657 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

The cardiac sympathetic co-transmitter galanin reduces acetylcholine release and vagal bradycardia: Implications for neural control of cardiac excitability

Herring, N., Cranley, J., Lokale, M. N., Li, D., Shanks, J., Alston, E. N., Girard, B. M., Carter, E., Parsons, R. L., Habecker, B. A. & Paterson, D. J., Mar 2012, In : Journal of molecular and cellular cardiology. 52, 3, p. 667-676 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Thermal instability of Δf508 cystic fibrosis transmembrane conductance regulator (CFTR) channel function: Protection by single suppressor mutations and inhibiting channel activity

Liu, X., O'Donnell, N., Landstrom, A., Skach, W. R. & Dawson, D. C., Jun 26 2012, In : Biochemistry. 51, 25, p. 5113-5124 12 p.

Research output: Contribution to journalArticle

26 Scopus citations

Thyroid hormone reduces cholesterol via a non-LDL receptor-mediated pathway

Goldberg, I. J., Huang, L. S., Huggins, L. A., Yu, S., Nagareddy, P. R., Scanlan, T. S. & Ehrenkranz, J. R., Nov 1 2012, In : Endocrinology. 153, 11, p. 5143-5149 7 p.

Research output: Contribution to journalArticle

52 Scopus citations
2011

3-iodothyronamine metabolism and functional effects in FRTL5 thyroid cells

Agretti, P., de Marco, G., Russo, L., Saba, A., Raffaelli, A., Marchini, M., Chiellini, G., Grasso, L., Pinchera, A., Vitti, P., Scanlan, T. S., Zucchi, R. & Tonacchera, M., Aug 1 2011, In : Journal of molecular endocrinology. 47, 1, p. 23-32 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

A FlAsH-based cross-linker to study protein interactions in living cells

Rutkowska, A., Haering, C. H. & Schultz, C., Dec 23 2011, In : Angewandte Chemie - International Edition. 50, 52, p. 12655-12658 4 p.

Research output: Contribution to journalArticle

27 Scopus citations

Altered norepinephrine content and ventricular function in p75NTR-/- mice after myocardial infarction

Lorentz, C. U., Woodward, W. R., Tharp, K. & Habecker, B. A., Oct 28 2011, In : Autonomic Neuroscience: Basic and Clinical. 164, 1-2, p. 13-19 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Analysis of agonist and antagonist effects on thyroid hormone receptor conformation by hydrogen/deuterium exchange

Figueira, A. C. M., Saidemberg, D. M., Souza, P. C. T., Martínez, L., Scanlan, T. S., Baxter, J. D., Skaf, M. S., Palma, M. S., Webb, P. & Polikarpov, I., Jan 1 2011, In : Molecular Endocrinology. 25, 1, p. 15-31 17 p.

Research output: Contribution to journalArticle

34 Scopus citations

Cardiac ischemia-reperfusion regulates sympathetic neuropeptide expression through gp130-dependent and independent mechanisms

Alston, E. N., Parrish, D. C., Hasan, W., Tharp, K., Pahlmeyer, L. & Habecker, B. A., Feb 1 2011, In : Neuropeptides. 45, 1, p. 33-42 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Cardioprotective effect of 3-iodothyronamine in perfused rat heart subjected to ischemia and reperfusion

Frascarelli, S., Ghelardoni, S., Chiellini, G., Galli, E., Ronca, F., Scanlan, T. S. & Zucchi, R., Aug 1 2011, In : Cardiovascular Drugs and Therapy. 25, 4, p. 307-313 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Cerebrotendinous xanthomatosis: A treatable disease with juvenile cataracts as a presenting sign

Monson, D. M., DeBarber, A. E., Bock, C. J., Anadiotis, G., Merkens, L. S., Steiner, R. D. & Stout, A. U., Aug 1 2011, In : Archives of ophthalmology. 129, 8, p. 1087-1088 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

Climbing fiber-evoked Purkinje cell discharge reduces expression of GABAA receptor-associated protein and decreases its interaction with GABAA receptors

Qian, Z., Yakhnitsa, V. & Barmack, N. H., Apr 1 2011, In : Journal of neurochemistry. 117, 2, p. 197-208 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Cystic fibrosis transmembrane conductance regulator: Temperature-dependent cysteine reactivity suggests different stable conformers of the conduction pathway

Liu, X. & Dawson, D. C., Nov 29 2011, In : Biochemistry. 50, 47, p. 10311-10317 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Cytokines inhibit norepinephrine transporter expression by decreasing Hand2

Pellegrino, M. J., Parrish, D. C., Zigmond, R. E. & Habecker, B. A., Mar 1 2011, In : Molecular and Cellular Neuroscience. 46, 3, p. 671-680 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Determination of cortisol production rates with contemporary liquid chromatography-mass spectrometry to measure cortisol-d3 dilution after infusion of deuterated tracer

Klopfenstein, B. J., Purnell, J. Q., Brandon, D. D., Isabelle, L. M. & DeBarber, A. E., Apr 1 2011, In : Clinical Biochemistry. 44, 5-6, p. 430-434 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Effects of the thyroid hormone derivatives 3-iodothyronamine and thyronamine on rat liver oxidative capacity

Venditti, P., Napolitano, G., Di Stefano, L., Chiellini, G., Zucchi, R., Scanlan, T. S. & Di Meo, S., Jul 20 2011, In : Molecular and Cellular Endocrinology. 341, 1-2, p. 55-62 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart

Edin, M. L., Wang, Z. J., Bradbury, J. A., Graves, J. P., Lih, F. B., DeGraff, L. M., Foley, J. F., Torphy, R., Ronnekleiv, O. K., Tomer, K. B., Lee, C. R. & Zeldin, D. C., Oct 1 2011, In : FASEB Journal. 25, 10, p. 3436-3447 12 p.

Research output: Contribution to journalArticle

86 Scopus citations

Fasting and 17β-estradiol differentially modulate the M-current in neuropeptide Y neurons

Roepke, T. A., Qiu, J., Smith, A. W., Ronnekleiv, O. K. & Kelly, M. J., Aug 17 2011, In : Journal of Neuroscience. 31, 33, p. 11825-11835 11 p.

Research output: Contribution to journalArticle

42 Scopus citations

GABA b-mediated inhibition of multiple modes of glutamate release in the nucleus of the solitary tract

Fawley, J. A., Peters, J. H. & Andresen, M. C., Oct 1 2011, In : Journal of neurophysiology. 106, 4, p. 1833-1840 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

GABAB restrains release from singly-evoked GABA terminals

Jin, Y. H. & Andresen, M. C., Oct 13 2011, In : Neuroscience. 193, p. 54-62 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
11 Scopus citations

Genetically encoded copper-free click chemistry

Plass, T., Milles, S., Koehler, C., Schultz, C. & Lemke, E. A., Apr 18 2011, In : Angewandte Chemie - International Edition. 50, 17, p. 3878-3881 4 p.

Research output: Contribution to journalArticle

197 Scopus citations

Guinea pig kisspeptin neurons are depolarized by leptin via activation of TRPC channels

Qiu, J., Fang, Y., Bosch, M. A., Rønnekleiv, O. K. & Kelly, M. J., Apr 2011, In : Endocrinology. 152, 4, p. 1503-1514 12 p.

Research output: Contribution to journalArticle

98 Scopus citations

Head position modulates optokinetic nystagmus

Pettorossi, V. E., Ferraresi, A., Botti, F. M., Panichi, R. & Barmack, N. H., Aug 1 2011, In : Experimental Brain Research. 213, 1, p. 141-152 12 p.

Research output: Contribution to journalArticle

Heterosynaptic crosstalk: GABA-glutamate metabotropic receptors interactively control glutamate release in solitary tract nucleus

Fernandes, L. G., Jin, Y. H. & Andresen, M. C., Feb 3 2011, In : Neuroscience. 174, p. 1-9 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Impaired baroreflex gain during pregnancy in conscious rats: Role of brain insulin

Azar, A. S. & Brooks, V. L., Feb 2011, In : Hypertension. 57, 2, p. 283-288 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions

Jackson, S. G., Al-Saigh, S., Schultz, C. & Junop, M. S., Feb 14 2011, In : BMC Structural Biology. 11, 11.

Research output: Contribution to journalArticle

9 Scopus citations

Insulin acts in the arcuate nucleus to increase lumbar sympathetic nerve activity and baroreflex function in rats

Cassaglia, P. A., Hermes, S. M., Aicher, S. A. & Brooks, V. L., Apr 1 2011, In : Journal of Physiology. 589, 7, p. 1643-1662 20 p.

Research output: Contribution to journalArticle

77 Scopus citations

Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice

Bradford, B. U., Lock, E. F., Kosyk, O., Kim, S., Uehara, T., Harbourt, D., DeSimone, M., Threadgill, D. W., Tryndyak, V., Pogribny, I. P., Bleyle, L., Koop, D. R. & Rusyn, I., 2011, In : Toxicological Sciences. 120, 1, p. 206-217 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

In vitro folding of K vAP, a voltage-gated K + channel

Devaraneni, P. K., Devereaux, J. J. & Valiyaveetil, F. I., Dec 6 2011, In : Biochemistry. 50, 48, p. 10442-10450 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

In vivo activity of the thyroid hormone receptor β- and α-selective agonists GC-24 and CO23 on rat liver, heart, and brain

Grijota-Martínez, C., Samarut, E., Scanlan, T. S., Morte, B. & Bernal, J., Mar 2011, In : Endocrinology. 152, 3, p. 1136-1142 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Localization of brain 5α-reductase messenger RNA in mice selectively bred for high chronic alcohol withdrawal severity

Roselli, C. E., Finn, T. J., Ronnekleiv-Kelly, S. M., Tanchuck, M. A., Kaufman, K. R. & Finn, D. A., Dec 1 2011, In : Alcohol. 45, 8, p. 763-772 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

MGluR8 modulates excitatory transmission in the bed nucleus of the stria terminalis in a stress-dependent manner

Gosnell, H. B., Silberman, Y., Grueter, B. A., Duvoisin, R. M., Raber, J. & Winder, D. G., Jul 1 2011, In : Neuropsychopharmacology. 36, 8, p. 1599-1607 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Microlesions of the inferior olive reduce vestibular modulation of purkinje cell complex and simple spikes in mouse cerebellum

Barmack, N. H. & Yakhnitsa, V., Jul 6 2011, In : Journal of Neuroscience. 31, 27, p. 9824-9835 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Molecular properties of kiss1 neurons in the arcuate nucleus of the mouse

Gottsch, M. L., Popa, S. M., Lawhorn, J. K., Qiu, J., Tonsfeldt, K. J., Bosch, M. A., Kelly, M. J., Rønnekleiv, O. K., Sanz, E., McKnight, G. S., Clifton, D. K., Palmiter, R. D. & Steiner, R. A., Nov 2011, In : Endocrinology. 152, 11, p. 4298-4309 12 p.

Research output: Contribution to journalArticle

87 Scopus citations

Neurotrophin-mediated dendrite-to-nucleus signaling revealed by microfluidic compartmentalization of dendrites

Cohen, M. S., Orth, C. B., Kim, H. J., Jeon, N. L. & Jaffrey, S. R., Jul 5 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 27, p. 11246-11251 6 p.

Research output: Contribution to journalArticle

64 Scopus citations

Opposing roles of mGluR8 in measures of anxiety involving non-social and social challenges

Duvoisin, R. M., Villasana, L., Davis, M. J., Winder, D. G. & Raber, J., Aug 1 2011, In : Behavioural Brain Research. 221, 1, p. 50-54 5 p.

Research output: Contribution to journalArticle

28 Scopus citations

Optimization of endochin-like quinolones for antimalarial activity

Winter, R., Kelly, J. X., Smilkstein, M. J., Hinrichs, D., Koop, D. R. & Riscoe, M. K., Feb 1 2011, In : Experimental Parasitology. 127, 2, p. 545-551 7 p.

Research output: Contribution to journalArticle

50 Scopus citations

Photoactivatable and cell-membrane-permeable phosphatidylinositol 3,4,5-trisphosphate

Mentel, M., Laketa, V., Subramanian, D., Gillandt, H. & Schultz, C., Apr 11 2011, In : Angewandte Chemie - International Edition. 50, 16, p. 3811-3814 4 p.

Research output: Contribution to journalArticle

48 Scopus citations

Physiological consequences of membrane-initiated estrogen signaling in the brain

Roepke, T. A., Ronnekleiv, O. K. & Kelly, M. J., Jan 1 2011, In : Frontiers in Bioscience. 16, 4, p. 1560-1573 14 p.

Research output: Contribution to journalArticle

84 Scopus citations

Profiling sterols in cerebrotendinous xanthomatosis: Utility of Girard derivatization and high resolution exact mass LC-ESI-MSn analysis

DeBarber, A. E., Sandlers, Y., Pappu, A. S., Merkens, L. S., Duell, P. B., Lear, S. R., Erickson, S. K. & Steiner, R. D., May 15 2011, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 879, 17-18, p. 1384-1392 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Rapid development of genetically encoded FRET reporters

Piljić, A., De Diego, I., Wilmanns, M. & Schultz, C., Jul 15 2011, In : ACS chemical biology. 6, 7, p. 685-691 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Regulation of NKB pathways and their roles in the control of Kiss1 neurons in the arcuate nucleus of the male mouse

Navarro, V. M., Gottsch, M. L., Wu, M., García-Galiano, D., Hobbs, S. J., Bosch, M. A., Pinilla, L., Clifton, D. K., Dearth, A., Ronnekleiv, O. K., Braun, R. E., Palmiter, R. D., Tena-Sempere, M., Alreja, M. & Steiner, R. A., Nov 2011, In : Endocrinology. 152, 11, p. 4265-4275 11 p.

Research output: Contribution to journalArticle

164 Scopus citations

Separate critical periods exist for testosterone-induced differentiation of the brain and genitals in sheep

Roselli, C. E., Estill, C. T., Stadelman, H. L., Meaker, M. & Stormshak, F., Jun 2011, In : Endocrinology. 152, 6, p. 2409-2415 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

STX, a novel nonsteroidal estrogenic compound, induces rapid action in primate GnRH neuronal calcium dynamics and peptide release

Kenealy, B. P., Keen, K. L., Rønnekleiv, O. K. & Terasawa, E., Aug 2011, In : Endocrinology. 152, 8, p. 3182-3191 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

Switching heterotrimeric G protein subunits with a chemical dimerizer

Putyrski, M. & Schultz, C., Sep 23 2011, In : Chemistry and Biology. 18, 9, p. 1126-1133 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

The effects of nitrogen-heme-iron coordination on substrate affinities for cytochrome P450 2E1

Jones, J. P., Joswig-Jones, C. A., Hebner, M., Chu, Y. & Koop, D. R., Aug 15 2011, In : Chemico-Biological Interactions. 193, 1, p. 50-56 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease

Zhou, Z., Duerr, J., Johannesson, B., Schubert, S. C., Treis, D., Harm, M., Graeber, S. Y., Dalpke, A., Schultz, C. & Mall, M. A., Jul 1 2011, In : Journal of Cystic Fibrosis. 10, SUPPL. 2, p. S172-S182

Research output: Contribution to journalArticle

90 Scopus citations

Thyronamines - Past, present, and future

Piehl, S., Hoefig, C. S., Scanlan, T. S. & Köhrle, J., Feb 1 2011, In : Endocrine reviews. 32, 1, p. 64-80 17 p.

Research output: Contribution to journalArticle

86 Scopus citations

TRPV1 marks synaptic segregation of multiple convergent afferents at the rat medial solitary tract nucleus

Peters, J. H., McDougall, S. J., Fawley, J. A. & Andresen, M. C., Sep 20 2011, In : PloS one. 6, 9, e25015.

Research output: Contribution to journalArticle

33 Scopus citations