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2012

Biosynthesis of 3-iodothyronamine (T1AM) is dependent on the sodium-iodide symporter and thyroperoxidase but does not involve extrathyroidal metabolism of T4

Hackenmueller, S. A., Marchini, M., Saba, A., Zucchi, R. & Scanlan, T. S., Nov 1 2012, In : Endocrinology. 153, 11, p. 5659-5667 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Calcium regulation of spontaneous and asynchronous neurotransmitter release

Smith, S. M., Chen, W., Vyleta, N. P., Williams, C., Lee, C. H., Phillips, C. & Andresen, M. C., Sep 2012, In : Cell Calcium. 52, 3-4, p. 226-233 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

CFTR regulates early pathogenesis of chronic obstructive lung disease in βenac-overexpressing mice

Johannesson, B., Hirtz, S., Schatterny, J., Schultz, C. & Mall, M. A., Aug 24 2012, In : PloS one. 7, 8, e44059.

Research output: Contribution to journalArticle

32 Scopus citations

Chemical genetic-mediated spatial regulation of protein expression in neurons reveals an axonal function for wld S

Cohen, M. S., Ghosh, A. K., Kim, H. J., Jeon, N. L. & Jaffrey, S. R., Feb 24 2012, In : Chemistry and Biology. 19, 2, p. 179-187 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Chronic psychostimulant exposure to adult, but not periadolescent rats reduces subsequent morphine antinociception

Cyr, M. C., Ingram, S. L., Aicher, S. A. & Morgan, M. M., Jun 1 2012, In : Pharmacology Biochemistry and Behavior. 101, 4, p. 538-543 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Ciliary neurotrophic factor stimulates tyrosine hydroxylase activity

Shi, X., Woodward, W. R. & Habecker, B. A., Jun 1 2012, In : Journal of Neurochemistry. 121, 5, p. 700-704 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Climbing fiber activity reduces 14-3-3-θ regulated GABA A receptor phosphorylation in cerebellar Purkinje cells

Qian, Z., Micorescu, M., Yakhnitsa, V. & Barmack, N. H., Jan 10 2012, In : Neuroscience. 201, p. 34-45 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Conformational analysis of a genetically encoded FRET biosensor by SAXS

Mertens, H. D. T., Piljić, A., Schultz, C. & Svergun, D. I., Jun 20 2012, In : Biophysical Journal. 102, 12, p. 2866-2875 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Cystic fibrosis transmembrane conductance regulator: A molecular model defines the architecture of the anion conduction path and locates a "bottleneck" in the pore

Norimatsu, Y., Ivetac, A., Alexander, C., Kirkham, J., Odonnell, N., Dawson, D. C. & Sansom, M. S. P., Mar 20 2012, In : Biochemistry. 51, 11, p. 2199-2212 14 p.

Research output: Contribution to journalArticle

48 Scopus citations

Descending projections from the rostral ventromedial medulla (RVM) to trigeminal and spinal dorsal horns are morphologically and neurochemically distinct

Aicher, S. A., Hermes, S. M., Whittier, K. L. & Hegarty, D. M., Mar 1 2012, In : Journal of Chemical Neuroanatomy. 43, 2, p. 103-111 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

Design, synthesis, and biological evaluation of conformationally constrained analogues of naphthol AS-E as inhibitors of CREB-mediated gene transcription

Jiang, M., Li, B. X., Xie, F., Delaney, F. & Xiao, X., Apr 26 2012, In : Journal of Medicinal Chemistry. 55, 8, p. 4020-4024 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Detection of 3-iodothyronamine in human patients: A preliminary study

Galli, E., Marchini, M., Saba, A., Berti, S., Tonacchera, M., Vitti, P., Scanlan, T. S., Iervasi, G. & Zucchi, R., Jan 1 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 1, p. E69-E74

Research output: Contribution to journalArticle

45 Scopus citations
16 Scopus citations

Distribution of CB1 cannabinoid receptors and their relationship with mu-opioid receptors in the rat periaqueductal gray

Wilson-Poe, A. R., Morgan, M. M., Aicher, S. A. & Hegarty, D. M., Jun 28 2012, In : Neuroscience. 213, p. 191-200 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Does the aromatic l-amino acid decarboxylase contribute to thyronamine biosynthesis?

Hoefig, C. S., Renko, K., Piehl, S., Scanlan, T. S., Bertoldi, M., Opladen, T., Hoffmann, G. F., Klein, J., Blankenstein, O., Schweizer, U. & Köhrle, J., Feb 26 2012, In : Molecular and Cellular Endocrinology. 349, 2, p. 195-201 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Effect of the ethinylestradiol/levonorgestrel combined oral contraceptive on the activity of cytochrome P4503A in obese women

Edelman, A., Munar, M., Elman, M. R., Koop, D. & Cherala, G., Sep 1 2012, In : British Journal of Clinical Pharmacology. 74, 3, p. 510-514 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Evidence for functional trace amine associated receptor-1 in normal and malignant B cells

Wasik, A. M., Millan, M. J., Scanlan, T., Barnes, N. M. & Gordon, J., Feb 1 2012, In : Leukemia Research. 36, 2, p. 245-249 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

Genetic Encoding of a Bicyclo[6.1.0]nonyne-Charged Amino Acid Enables Fast Cellular Protein Imaging by Metal-Free Ligation

Borrmann, A., Milles, S., Plass, T., Dommerholt, J., Verkade, J. M. M., Wießler, M., Schultz, C., van Hest, J. C. M., van Delft, F. L. & Lemke, E. A., Sep 24 2012, In : ChemBioChem. 13, 14, p. 2094-2099 6 p.

Research output: Contribution to journalArticle

116 Scopus citations
23 Scopus citations
27 Scopus citations

Insulinotropic effect of the non-steroidal compound STX in pancreatic β-cells

Ropero, A. B., Alonso-Magdalena, P., Soriano, S., Juan-Picó, P., Roepke, T. A., Kelly, M. J. & Nadal, Á., Apr 10 2012, In : PloS one. 7, 4, e34650.

Research output: Contribution to journalArticle

Kisspeptin expression in guinea pig hypothalamus: Effects of 17β-estradiol

Bosch, M. A., Xue, C. & Rønnekleiv, O. K., Jul 1 2012, In : Journal of Comparative Neurology. 520, 10, p. 2143-2162 20 p.

Research output: Contribution to journalArticle

31 Scopus citations

Liver X receptor modulation of gene expression leading to proluteolytic effects in primate luteal cells

Bogan, R. L., Debarber, A. E. & Hennebold, J. D., Mar 1 2012, In : Biology of reproduction. 86, 3, 89.

Research output: Contribution to journalArticle

7 Scopus citations

Locating a plausible binding site for an open-channel blocker, GlyH-101, in the pore of the cystic fibrosis transmembrane conductance regulator

Norimatsu, Y., Ivetac, A., Alexander, C., O'Donnell, N., Frye, L., Sansom, M. S. P. & Dawson, D. C., Dec 1 2012, In : Molecular pharmacology. 82, 6, p. 1042-1055 14 p.

Research output: Contribution to journalArticle

28 Scopus citations

Low-fidelity GABA transmission within a dense excitatory network of the solitary tract nucleus

Mcdougall, S. J. & Andresen, M. C., Nov 1 2012, In : Journal of Physiology. 590, 22, p. 5677-5689 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

mCLCA3 does not contribute to calcium-activated chloride conductance in murine airways

Mundhenk, L., Johannesson, B., Anagnostopoulou, P., Braun, J., Bothe, M. K., Schultz, C., Mall, M. A. & Gruber, A. D., Jul 1 2012, In : American journal of respiratory cell and molecular biology. 47, 1, p. 87-93 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Measures of anxiety, sensorimotor function, and memory in male and female mGluR4 -/- mice

Davis, M. J., Haley, T., Duvoisin, R. M. & Raber, J., Apr 1 2012, In : Behavioural Brain Research. 229, 1, p. 21-28 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

Membrane estrogen receptor regulation of hypothalamic function

Micevych, P. E. & Kelly, M. J., Sep 1 2012, In : Neuroendocrinology. 96, 2, p. 103-110 8 p.

Research output: Contribution to journalArticle

68 Scopus citations

Midline thalamic paraventricular nucleus neurons display diurnal variation in resting membrane potentials, conductances, and firing patterns in vitro

Kolaj, M., Zhang, L., Rønnekleiv, O. K. & Renaud, L. P., Apr 1 2012, In : Journal of neurophysiology. 107, 7, p. 1835-1844 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Naloxone pro-drug rescues morphine induced respiratory depression in Sprague-Dawley rats

Wallisch, M., El Rody, N. M., Huang, B., Koop, D. R., Baker, J. R. & Olsen, G. D., Jan 15 2012, In : Respiratory Physiology and Neurobiology. 180, 1, p. 52-60 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

No evidence for mevalonate shunting in moderately affected children with Smith-Lemli-Opitz syndrome

Roullet, J. B., Merkens, L. S., Pappu, A. S., Jacobs, M. D., Winter, R., Connor, W. E. & Steiner, R. D., Sep 1 2012, In : Journal of inherited metabolic disease. 35, 5, p. 859-869 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Ontogeny of Cytochrome P450 Aromatase mRNA Expression in the Developing Sheep Brain

Roselli, C. E. & Stormshak, F., Mar 1 2012, In : Journal of Neuroendocrinology. 24, 3, p. 443-452 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Opioids inhibit visceral afferent activation of catecholamine neurons in the solitary tract nucleus

Cui, R. J., Roberts, B. L., Zhao, H., Andresen, M. C. & Appleyard, S. M., Oct 11 2012, In : Neuroscience. 222, p. 181-190 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

ProNGF, a cytokine induced after myocardial infarction in humans, targets pericytes to promote microvascular damage and activation

Siao, C. J., Lorentz, C. U., Kermani, P., Marinic, T., Carter, J., McGrath, K., Padow, V. A., Mark, W., Falcone, D. J., Leona, C. G., Parrish, D. C., Habecker, B. A., Nykjaer, A., Ellenson, L. H., Tessarollo, L. & Hempstead, B. L., Nov 1 2012, In : Journal of Experimental Medicine. 209, 12, p. 2291-2305 15 p.

Research output: Contribution to journalArticle

38 Scopus citations

Protein tango: The toolbox to capture interacting partners

Rutkowska, A. & Schultz, C., Aug 13 2012, In : Angewandte Chemie - International Edition. 51, 33, p. 8166-8176 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

Serafimova, I. M., Pufall, M. A., Krishnan, S., Duda, K., Cohen, M. S., Maglathlin, R. L., McFarland, J. M., Miller, R. M., Frödin, M. & Taunton, J., May 2012, In : Nature Chemical Biology. 8, 5, p. 471-476 6 p.

Research output: Contribution to journalArticle

225 Scopus citations
19 Scopus citations

Serotonin 5-HT 2C receptor-mediated inhibition of the M-current in hypothalamic POMC neurons

Roepke, T. A., Smith, A. W., Rønnekleiv, O. K. & Kelly, M. J., Jun 1 2012, In : American Journal of Physiology - Endocrinology and Metabolism. 302, 11, p. E1399-E1406

Research output: Contribution to journalArticle

24 Scopus citations

Spatially resolved monitoring of neutrophil elastase activity with ratiometric fluorescent reporters

Gehrig, S., Mall, M. A. & Schultz, C., Jun 18 2012, In : Angewandte Chemie - International Edition. 51, 25, p. 6258-6261 4 p.

Research output: Contribution to journalArticle

37 Scopus citations
24 Scopus citations

Target-activated prodrugs (TAPs) for the autoregulated inhibition of MMP12

Cobos-Correa, A., Stein, F. & Schultz, C., Aug 9 2012, In : ACS Medicinal Chemistry Letters. 3, 8, p. 653-657 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

The cardiac sympathetic co-transmitter galanin reduces acetylcholine release and vagal bradycardia: Implications for neural control of cardiac excitability

Herring, N., Cranley, J., Lokale, M. N., Li, D., Shanks, J., Alston, E. N., Girard, B. M., Carter, E., Parsons, R. L., Habecker, B. A. & Paterson, D. J., Mar 1 2012, In : Journal of molecular and cellular cardiology. 52, 3, p. 667-676 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

Thermal instability of Δf508 cystic fibrosis transmembrane conductance regulator (CFTR) channel function: Protection by single suppressor mutations and inhibiting channel activity

Liu, X., O'Donnell, N., Landstrom, A., Skach, W. R. & Dawson, D. C., Jun 26 2012, In : Biochemistry. 51, 25, p. 5113-5124 12 p.

Research output: Contribution to journalArticle

26 Scopus citations

Thyroid hormone reduces cholesterol via a non-LDL receptor-mediated pathway

Goldberg, I. J., Huang, L. S., Huggins, L. A., Yu, S., Nagareddy, P. R., Scanlan, T. S. & Ehrenkranz, J. R., Nov 1 2012, In : Endocrinology. 153, 11, p. 5143-5149 7 p.

Research output: Contribution to journalArticle

51 Scopus citations
2011

3-iodothyronamine metabolism and functional effects in FRTL5 thyroid cells

Agretti, P., de Marco, G., Russo, L., Saba, A., Raffaelli, A., Marchini, M., Chiellini, G., Grasso, L., Pinchera, A., Vitti, P., Scanlan, T. S., Zucchi, R. & Tonacchera, M., Aug 1 2011, In : Journal of molecular endocrinology. 47, 1, p. 23-32 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

A FlAsH-based cross-linker to study protein interactions in living cells

Rutkowska, A., Haering, C. H. & Schultz, C., Dec 23 2011, In : Angewandte Chemie - International Edition. 50, 52, p. 12655-12658 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Altered norepinephrine content and ventricular function in p75NTR-/- mice after myocardial infarction

Lorentz, C. U., Woodward, W. R., Tharp, K. & Habecker, B. A., Oct 28 2011, In : Autonomic Neuroscience: Basic and Clinical. 164, 1-2, p. 13-19 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Analysis of agonist and antagonist effects on thyroid hormone receptor conformation by hydrogen/deuterium exchange

Figueira, A. C. M., Saidemberg, D. M., Souza, P. C. T., Martínez, L., Scanlan, T. S., Baxter, J. D., Skaf, M. S., Palma, M. S., Webb, P. & Polikarpov, I., Jan 1 2011, In : Molecular Endocrinology. 25, 1, p. 15-31 17 p.

Research output: Contribution to journalArticle

32 Scopus citations

Cardiac ischemia-reperfusion regulates sympathetic neuropeptide expression through gp130-dependent and independent mechanisms

Alston, E. N., Parrish, D. C., Hasan, W., Tharp, K., Pahlmeyer, L. & Habecker, B. A., Feb 1 2011, In : Neuropeptides. 45, 1, p. 33-42 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Cardioprotective effect of 3-iodothyronamine in perfused rat heart subjected to ischemia and reperfusion

Frascarelli, S., Ghelardoni, S., Chiellini, G., Galli, E., Ronca, F., Scanlan, T. S. & Zucchi, R., Aug 1 2011, In : Cardiovascular Drugs and Therapy. 25, 4, p. 307-313 7 p.

Research output: Contribution to journalArticle

29 Scopus citations