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2017

Elevated serum tetrac in graves disease: Potential pathogenic role in thyroid-associated ophthalmopathy

Fernando, R., Placzek, E., Reese, E. A., Placzek, A. T., Schwartz, S., Trierweiler, A., Niziol, L. M., Raychaudhuri, N., Atkins, S., Scanlan, T. T. & Smith, T. J., Mar 1 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 3, p. 776-785 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Endogenous opioids regulate moment-to-moment neuronal communication and excitability

Winters, B. L., Gregoriou, G. C., Kissiwaa, S. A., Wells, O. A., Medagoda, D. I., Hermes, S. M., Burford, N. T., Alt, A., Aicher, S. A. & Bagley, E. E., Mar 22 2017, In : Nature communications. 8, 14611.

Research output: Contribution to journalArticle

16 Scopus citations

Endosomal phosphatidylinositol 3-phosphate promotes gephyrin clustering and GABAergic neurotransmission at inhibitory postsynapses

Papadopoulos, T., Rhee, H. J., Subramanian, D., Paraskevopoulou, F., Mueller, R., Schultz, C., Brose, N., Rhee, J. S. & Betz, H., Jan 27 2017, In : Journal of Biological Chemistry. 292, 4, p. 1160-1177 18 p.

Research output: Contribution to journalArticle

14 Scopus citations

Ester-to-amide rearrangement of ethanolamine-derived prodrugs of sobetirome with increased blood-brain barrier penetration

Ferrara, S. J., Meinig, J. M., Placzek, A. T., Banerji, T., McTigue, P., Hartley, M. D., Sanford-Crane, H. S., Banerji, T., Bourdette, D. & Scanlan, T. T., May 15 2017, In : Bioorganic and Medicinal Chemistry. 25, 10, p. 2743-2753 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Fos expression in the olfactory pathway of high- and low-sexually performing rams exposed to urine from estrous or ovariectomized ewes

Mirto, A. J., Austin, K. J., Uthlaut, V. A., Roselli, C. & Alexander, B. M., Jan 1 2017, In : Applied Animal Behaviour Science. 186, p. 22-28 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

GLP-1R signaling directly activates arcuate nucleus kisspeptin action in brain slices but does not rescue luteinizing hormone inhibition in ovariectomized mice during negative energy balance

Heppner, K. M., Baquero, A. F., Bennett, C. M., Lindsley, S. R., Kirigiti, M. A., Bennett, B., Bosch, M. A., Mercer, A. J., Rønnekleiv, O. K., True, C., Grove, K. L. & Smith, M. S., Jan 5 2017, In : eNeuro. 4, 1, e0198.

Research output: Contribution to journalArticle

10 Scopus citations

Implication of thyroid hormone signaling in neural crest cells migration: Evidence from thyroid hormone receptor beta knockdown and NH3 antagonist studies

Bronchain, O. J., Chesneau, A., Monsoro-Burq, A. H., Jolivet, P., Paillard, E., Scanlan, T. S., Demeneix, B. A., Sachs, L. M. & Pollet, N., Jan 5 2017, In : Molecular and Cellular Endocrinology. 439, p. 233-246 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration

Ma, H., Yang, F., Butler, M. R., Belcher, J., Redmond, T. M., Placzek, A. T., Scanlan, T. S. & Ding, X. Q., Aug 2017, In : FASEB Journal. 31, 8, p. 3425-3438 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Intestinal Metabolites Are Profoundly Altered in the Context of HLA-B27 Expression and Functionally Modulate Disease in a Rat Model of Spondyloarthritis

Asquith, M., Davin, S., Stauffer, P., Michell, C., Janowitz, C., Lin, P., Ensign-Lewis, J., Kinchen, J. M., Koop, D. & Rosenbaum, J. J., Oct 1 2017, In : Arthritis & rheumatology (Hoboken, N.J.). 69, 10, p. 1984-1995 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

Longitudinal study on the use of dried blood spots for home monitoring in children after kidney transplantation

Al-Uzri, A., Freeman, K., Wade, J., Clark, K., Bleyle, L. A., Munar, M. & Koop, D., 2017, (Accepted/In press) In : Pediatric Transplantation.

Research output: Contribution to journalArticle

11 Scopus citations

Optical control of GPR40 signalling in pancreatic β-cells

Frank, J. A., Yushchenko, D. A., Fine, N. H. F., Duca, M., Citir, M., Broichhagen, J., Hodson, D. J., Schultz, C. & Trauner, D., Jan 1 2017, In : Chemical Science. 8, 11, p. 7604-7610 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Parasympathetic dysfunction and antiarrhythmic effect of vagal nerve stimulation following myocardial infarction

Vaseghi, M., Salavatian, S., Rajendran, P. S., Yagishita, D., Woodward, W. R., Hamon, D., Yamakawa, K., Irie, T., Habecker, B. A. & Shivkumar, K., Aug 17 2017, In : JCI Insight. 2, 16

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis

Walter, A. M., Müller, R., Tawfik, B., Wierda, K. D., Pinheiro, P. S., Nadler, A., McCarthy, A. W., Ziomkiewicz, I., Kruse, M., Reither, G., Rettig, J., Lehmann, M., Haucke, V., Hille, B., Schultz, C. & Sørensen, J. B., Oct 25 2017, In : eLife. 6, e30203.

Research output: Contribution to journalArticle

12 Scopus citations

Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy

Kratochvil, H. T., Maj, M., Matulef, K., Annen, A. W., Ostmeyer, J., Perozo, E., Roux, B., Valiyaveetil, F. & Zanni, M. T., Jul 5 2017, In : Journal of the American Chemical Society. 139, 26, p. 8837-8845 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Protean proteases: At the cutting edge of lung diseases

Taggart, C., Mall, M. A., Lalmanach, G., Cataldo, D., Ludwig, A., Janciauskiene, S., Heath, N., Meiners, S., Overall, C. M., Schultz, C., Turk, B. & Borensztajn, K. S., Feb 1 2017, In : European Respiratory Journal. 49, 2, 1501200.

Research output: Contribution to journalArticle

23 Scopus citations

Renal denervation in male rats with heart failure improves ventricular sympathetic nerve innervation and function

Pinkham, M. I., Loftus, M. T., Amirapu, S., Guild, S. J., Quill, G., Woodward, W. R., Habecker, B. A. & Barrett, C. J., Mar 10 2017, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 312, 3, p. R368-R379

Research output: Contribution to journalArticle

6 Scopus citations

Select noxious stimuli induce changes on corneal nerve morphology

Hegarty, D. M., Hermes, S. M., Yang, K. & Aicher, S., Jun 1 2017, In : Journal of Comparative Neurology. 525, 8, p. 2019-2031 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development

Bulusu, V., Prior, N., Snaebjornsson, M. T., Kuehne, A., Sonnen, K. F., Kress, J., Stein, F., Schultz, C., Sauer, U. & Aulehla, A., Feb 27 2017, In : Developmental Cell. 40, 4, p. 331-341.e4

Research output: Contribution to journalArticle

26 Scopus citations

Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors

Thorsell, A. G., Ekblad, T., Karlberg, T., Löw, M., Pinto, A. F., Trésaugues, L., Moche, M., Cohen, M. & Schüler, H., Feb 23 2017, In : Journal of Medicinal Chemistry. 60, 4, p. 1262-1271 10 p.

Research output: Contribution to journalArticle

75 Scopus citations

Synchronized HIV assembly by tunable PIP2 changes reveals PIP2 requirement for stable gag anchoring

Mücksch, F., Laketa, V., Müller, B., Schultz, C. & Kräusslich, H. G., Jun 2 2017, In : eLife. 6, e25287.

Research output: Contribution to journalArticle

11 Scopus citations

Targeting Fatty-Acid Amide Hydrolase with Prodrugs for CNS-Selective Therapy

Meinig, J. M., Ferrara, S. J., Banerji, T., Banerji, T., Sanford-Crane, H. S., Bourdette, D. & Scanlan, T. T., Nov 15 2017, In : ACS Chemical Neuroscience. 8, 11, p. 2468-2476 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

The future of graduate and postdoctoral training in the biosciences

Hitchcock, P., Mathur, A., Bennett, J., Cameron, P., Chow, C., Clifford, P., Duvoisin, R., Feig, A., Finneran, K., Klotz, D. M., McGee, R., O’Riordan, M., Pfund, C., Pickett, C., Schwartz, N., Street, N. E., Watkins, E., Wiest, J. & Engelke, D., Oct 19 2017, In : eLife. 6, e32715.

Research output: Contribution to journalArticle

10 Scopus citations

Thyroid Hormone Status in Sitosterolemia Is Modified by Ezetimibe

Othman, R. A., Myrie, S. B., Mymin, D., Roullet, J. B., DeBarber, A. E., Steiner, R. D. & Jones, P. J. H., Sep 2017, In : Journal of Pediatrics. 188, p. 198-204.e1

Research output: Contribution to journalArticle

3 Scopus citations

Torso geometry reconstruction and body surface electrode localization using three-dimensional photography

Perez-Alday, E. A., Thomas, J. A., Kabir, M., Sedaghat, G., Rogovoy, N., van Dam, E., van Dam, P., Woodward, W., Fuss, C., Ferencik, M. & Tereshchenko, L., 2017, (Accepted/In press) In : Journal of Electrocardiology.

Research output: Contribution to journalArticle

3 Scopus citations

Trifunctional lipid probes for comprehensive studies of single lipid species in living cells

Höglinger, D., Nadler, A., Haberkant, P., Kirkpatrick, J., Schifferer, M., Stein, F., Hauke, S., Porter, F. D. & Schultz, C., Feb 14 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 7, p. 1566-1571 6 p.

Research output: Contribution to journalArticle

47 Scopus citations

Tyrosine hydroxylase in the ventral tegmental area of rams with high or low libido—A role for dopamine

Kramer, A. C., Mirto, A. J., Austin, K. J., Roselli, C. & Alexander, B. M., Dec 1 2017, In : Animal Reproduction Science. 187, p. 152-158 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

β-Adrenergic inhibition prevents action potential and calcium handling changes during regional myocardial ischemia

Murphy, S. R., Wang, L., Wang, Z., Domondon, P., Di Lang, L., Habecker, B. A., Myles, R. C. & Ripplinger, C. M., Aug 28 2017, In : Frontiers in Physiology. 8, AUG, 630.

Research output: Contribution to journalArticle

3 Scopus citations
2016

A comparison of salivary testosterone measurement using immunoassays and tandem mass spectrometry

Welker, K. M., Lassetter, B., Brandes, C. M., Prasad, S., Koop, D. R. & Mehta, P. H., Sep 1 2016, In : Psychoneuroendocrinology. 71, p. 180-188 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state

Padilla, S. L., Qiu, J., Soden, M. E., Sanz, E., Nestor, C. C., Barker, F. D., Quintana, A., Zweifel, L. S., Rønnekleiv, O. K., Kelly, M. J. & Palmiter, R. D., May 1 2016, In : Nature Neuroscience. 19, 5, p. 734-741 8 p.

Research output: Contribution to journalArticle

85 Scopus citations

A Ratiometric Sensor for Imaging Insulin Secretion in Single β Cells

Schifferer, M., Yushchenko, D. A., Stein, F., Bolbat, A. & Schultz, C., Mar 22 2016, (Accepted/In press) In : Cell Chemical Biology.

Research output: Contribution to journalArticle

4 Scopus citations

A role for adenine nucleotides in the sensing mechanism to purine starvation in Leishmania donovani

Martin, J. L., Yates, P., Boitz, J. M., Koop, D., Fulwiler, A. L., Cassera, M. B., Ullman, B. & Carter, N., Jul 1 2016, In : Molecular Microbiology. 101, 2, p. 299-313 15 p.

Research output: Contribution to journalArticle

9 Scopus citations

Biosensor reveals multiple sources for mitochondrial NAD+

Cambronne, X. A., Stewart, M. L., Kim, D., Jones-Brunette, A. M., Morgan, R. K., Farrens, D. L., Cohen, M. S. & Goodman, R. H., Jun 17 2016, In : Science. 352, 6292, p. 1474-1477 4 p.

Research output: Contribution to journalArticle

126 Scopus citations

BMP7-induced dendritic growth in sympathetic neurons requires p75NTR signaling

Courter, L. A., Shaffo, F. C., Ghogha, A., Parrish, D. J., Lorentz, C. U., Habecker, B. A. & Lein, P. J., Jan 1 2016, In : Developmental Neurobiology. 76, 9, p. 1003-1013 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Cell-specific Profiling of Nascent Proteomes Using Orthogonal Enzyme-mediated Puromycin Incorporation

Barrett, R. M., Liu, H. W., Jin, H., Goodman, R. & Cohen, M., Jun 17 2016, In : ACS Chemical Biology. 11, 6, p. 1532-1536 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo

Pavlovic, I., Thakor, D. T., Vargas, J. R., McKinlay, C. J., Hauke, S., Anstaett, P., Camunã, R. C., Bigler, L., Gasser, G., Schultz, C., Wender, P. A. & Jessen, H. J., Feb 4 2016, In : Nature communications. 7, 10622.

Research output: Contribution to journalArticle

44 Scopus citations

Combining in Vitro Folding with Cell Free Protein Synthesis for Membrane Protein Expression

Focke, P. J., Hein, C., Hoffmann, B., Matulef, K., Bernhard, F., Dötsch, V. & Valiyaveetil, F., Aug 2 2016, In : Biochemistry. 55, 30, p. 4212-4219 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Concentration accuracy of compounded mitomycin C for ophthalmic surgery

Kinast, R. M., Akula, K. K., Mansberger, S. L., Barker, G. T., Gardiner, S. K., Whitson, E. & De Barber, A., Feb 1 2016, In : JAMA Ophthalmology. 134, 2, p. 191-195 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites

Simon, B., Huart, A. S., Temmerman, K., Vahokoski, J., Mertens, H. D. T., Komadina, D., Hoffmann, J. E., Yumerefendi, H., Svergun, D. I., Kursula, P., Schultz, C., McCarthy, A. A., Hart, D. J. & Wilmanns, M., Jun 7 2016, In : Structure. 24, 6, p. 851-861 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Dedicated C-fibre viscerosensory pathways to central nucleus of the amygdala

Mcdougall, S. J., Guo, H. & Andresen, M., 2016, (Accepted/In press) In : Journal of Physiology.

Research output: Contribution to journalArticle

5 Scopus citations
7 Scopus citations

Diphenylether-Modified 1,2-Diamines with Improved Drug Properties for Development against Mycobacterium tuberculosis

Foss, M. H., Pou, S., Davidson, P. M., Dunaj, J. L., Winter, R. W., Pou, S., Licon, M. H., Doh, J. K., Li, Y., Kelly, J. X., Dodean, R. A., Koop, D., Riscoe, M. & Purdy, G., Jul 8 2016, In : ACS Infectious Diseases. 2, 7, p. 500-508 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Disrupting protein tyrosine phosphatase σ does not prevent sympathetic axonal dieback following myocardial infarction

Johnsen, D., Olivas, A., Lang, B., Silver, J. & Habecker, B., Feb 1 2016, In : Experimental Neurology. 276, p. 1-4 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Distinct calcium sources support multiple modes of synaptic release from cranial sensory afferents

Fawley, J. A., Hofmann, M. E. & Andresen, M., Aug 24 2016, In : Journal of Neuroscience. 36, 34, p. 8957-8966 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Effects of Long-Term Flutamide Treatment During Development on Sexual Behaviour and Hormone Responsiveness in Rams

Roselli, C., Meaker, M., Stormshak, F. & Estill, C. T., May 1 2016, In : Journal of Neuroendocrinology. 28, 5

Research output: Contribution to journalArticle

3 Scopus citations

ERK5 induces ankrd1 for catecholamine biosynthesis and homeostasis in adrenal medullary cells

Obara, Y., Nagasawa, R., Nemoto, W., Pellegrino, M. J., Takahashi, M., Habecker, B. A., Stork, P. J. S., Ichiyanagi, O., Ito, H., Tomita, Y., Ishii, K. & Nakahata, N., Mar 1 2016, In : Cellular Signalling. 28, 3, p. 177-189 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Estradiol Rapidly Attenuates ORL-1 Receptor-Mediated Inhibition of Proopiomelanocortin Neurons via Gq-Coupled, Membrane-Initiated Signaling

Conde, K., Meza, C., Kelly, M. J., Sinchak, K. & Wagner, E. J., Sep 1 2016, In : Neuroendocrinology. 103, 6, p. 787-805 19 p.

Research output: Contribution to journalArticle

12 Scopus citations

Excess testosterone exposure alters hypothalamic-pituitary-Testicular axis dynamics and gene expression in sheep fetuses

Roselli, C. E., Amodei, R., Gribbin, K. P., Corder, K., Stormshak, F. & Estill, C. T., Nov 2016, In : Endocrinology. 157, 11, p. 4234-4245 12 p.

Research output: Contribution to journalArticle

6 Scopus citations
22 Scopus citations

Fragile X Mental Retardation Protein expression in the retina is regulated by light

Guimarães-Souza, E. M., Perche, O., Morgans, C., Duvoisin, R. & Calaza, K. C., May 1 2016, In : Experimental Eye Research. 146, p. 72-82 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Functional screening for G protein-coupled receptor targets of 14,15-epoxyeicosatrienoic acid

Liu, X., Qian, Z. Y., Xie, F., Fan, W., Nelson, J. W., Xiao, X., Kaul, S., Barnes, A. & Alkayed, N., Apr 28 2016, (Accepted/In press) In : Prostaglandins and Other Lipid Mediators.

Research output: Contribution to journalArticle

17 Scopus citations