Research Output 1997 2019

2008
62 Citations (Scopus)

Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers

Dorrell, C., Abraham, S. L., Lanxon-Cookson, K. M., Canaday, P. S., Streeter, P. & Grompe, M., Sep 2008, In : Stem Cell Research. 1, 3, p. 183-194 12 p.

Research output: Contribution to journalArticle

Cell Culture Techniques
Islets of Langerhans
Pancreas
Antibodies
Hybridomas
8 Citations (Scopus)

Metachronous manifestations of Sweet's syndrome in a neutropenic patient with Fanconi anemia

Chatham-Stephens, K., Devere, T., Guzman-Cottrill, J. & Kurre, P., Jul 2008, In : Pediatric Blood and Cancer. 51, 1, p. 128-130 3 p.

Research output: Contribution to journalArticle

Sweet Syndrome
Fanconi Anemia
Dermis
Lung
Pancytopenia
20 Citations (Scopus)

MHC class II derived recombinant T cell receptor ligands protect DBA/1LacJ mice from collagen-induced arthritis

Huan, J., Kaler, L. J., Mooney, J. L., Subramanian, S., Hopke, C., Vandenbark, A., Rosloniec, E. F., Burrows, G. G. & Offner, H., Jan 15 2008, In : Journal of Immunology. 180, 2, p. 1249-1257 9 p.

Research output: Contribution to journalArticle

Inbred DBA Mouse
Experimental Arthritis
T-Cell Antigen Receptor
Ligands
Rheumatoid Arthritis
31 Citations (Scopus)

Pre-clinical safety testing supporting clinical use of allogeneic multipotent adult progenitor cells

Kovacsovics-Bankowski, M., Mauch, K., Raber, A., Streeter, P., Deans, R. J., Maziarz, R. & Van't Hof, W., 2008, In : Cytotherapy. 10, 7, p. 730-742 13 p.

Research output: Contribution to journalArticle

Stem Cells
Safety
Clinical Chemistry
Hematopoietic Stem Cell Transplantation
Hematology
75 Citations (Scopus)

Surface markers for the murine oval cell response

Dorrell, C., Erker, L., Lanxon-Cookson, K. M., Abraham, S. L., Victoroff, T., Ro, S., Canaday, P. S., Streeter, P. & Grompe, M., Oct 2008, In : Hepatology. 48, 4, p. 1282-1291 10 p.

Research output: Contribution to journalArticle

Liver
Monoclonal Antibodies
Inbred F344 Rats
Surface Antigens
Hepatocytes
55 Citations (Scopus)

Tempol protects against oxidative damage and delays epithelial tumor onset in Fanconi anemia mice

Zhang, Q-S., Eaton, L., Snyder, E. R., Houghtaling, S., Mitchell, J. B., Finegold, M., Van Waes, C. & Grompe, M., Mar 1 2008, In : Cancer Research. 68, 5, p. 1601-1608 8 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Neoplasms
Antioxidants
tempol
Inborn Genetic Diseases
39 Citations (Scopus)

Therapeutic vaccination with a trivalent T-cell receptor (TCR) peptide vaccine restores deficient FoxP3 expression and TCR recognition in subjects with multiple sclerosis

Vandenbark, A., Culbertson, N. E., Bartholomew, R. M., Huan, J., Agotsch, M., LaTocha, D., Yadav, V., Mass, M., Whitham, R., Lovera, J., Milano, J., Theofan, G., Chou, Y. K., Offner, H. & Bourdette, D., Jan 2008, In : Immunology. 123, 1, p. 66-78 13 p.

Research output: Contribution to journalArticle

Subunit Vaccines
T-Cell Antigen Receptor
Multiple Sclerosis
Vaccination
Regulatory T-Lymphocytes
22 Citations (Scopus)

Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma

Liu, H., Huang, J., Wang, J., Jiang, S., Bailey, A. S., Goldman, D., Welcker, M., Bedell, V., Slovak, M. L., Clurman, B., Thayer, M. M., Fleming, W. & Epner, E., Aug 4 2008, In : Journal of Experimental Medicine. 205, 8, p. 1843-1858 16 p.

Research output: Contribution to journalArticle

Mantle-Cell Lymphoma
Cyclin D1
Immunoglobulin Heavy Chains
Multiple Myeloma
Cell Line
2007
40 Citations (Scopus)
Autoimmune Experimental Encephalomyelitis
Interleukin-17
T-Cell Antigen Receptor
Multiple Sclerosis
Cell Movement
21 Citations (Scopus)

GATA-2 functions downstream of BMPs and CaM KIV in ectodermal cells during primitive hematopoiesis

Dalgin, G., Goldman, D., Donley, N., Ahmed, R., Eide, C. A. & Christian, J. L., Oct 15 2007, In : Developmental Biology. 310, 2, p. 454-469 16 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 4
Bone Morphogenetic Proteins
Hematopoiesis
Ectoderm
Erythropoiesis
30 Citations (Scopus)

Multiarm high-throughput integration site detection: Limitations of LAM-PCR technology and optimization for clonal analysis

Harkey, M. A., Kaul, R., Jacobs, M. A., Kurre, P., Bovee, D., Levy, R. & Blau, C. A., Jun 2007, In : Stem Cells and Development. 16, 3, p. 381-392 12 p.

Research output: Contribution to journalArticle

Clone Cells
Technology
Polymerase Chain Reaction
Hematopoietic Stem Cells
Stem Cells
25 Citations (Scopus)

Prolonged adherence of human immunodeficiency virus-derived vector particles to hematopoietic target cells leads to secondary transduction in vitro and in vivo

Pan, Y. W., Scarlett, J. M., Luoh, T. T. & Kurre, P., Jan 2007, In : Journal of Virology. 81, 2, p. 639-649 11 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus
Vesicular Stomatitis
HIV
Vesiculovirus
biosafety
2006
199 Citations (Scopus)

Bone marrow-derived cells fuse with normal and transformed intestinal stem cells

Rizvi, A. Z., Swain, J. R., Davies, P., Bailey, A. S., Decker, A. D., Willenbring, H., Grompe, M., Fleming, W. & Wong, M., Apr 18 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 16, p. 6321-6325 5 p.

Research output: Contribution to journalArticle

Bone Marrow Cells
Stem Cells
Cell Fusion
Intestines
Regeneration
7 Citations (Scopus)

Ectodermally derived steel/stem cell factor functions non-cell autonomously during primitive erythropoiesis in Xenopus

Goldman, D., Berg, L. K., Heinrich, M. & Christian, J. L., Apr 15 2006, In : Blood. 107, 8, p. 3114-3121 8 p.

Research output: Contribution to journalArticle

Stem Cell Factor
Erythropoiesis
Steel
Xenopus
Mesoderm
109 Citations (Scopus)

hnRNP A1 associates with telomere ends and stimulates telomerase activity

Zhang, Q-S., Manche, L., Xu, R. M. & Krainer, A. R., Jun 2006, In : RNA. 12, 6, p. 1116-1128 13 p.

Research output: Contribution to journalArticle

Telomerase
Telomere
G-Quadruplexes
Heterogeneous-Nuclear Ribonucleoprotein Group A-B
Holoenzymes
54 Citations (Scopus)

In vivo genetic selection of renal proximal tubules

Held, P. K., Al-Dhalimy, M., Willenbring, H., Akkari, Y., Jiang, S., Torimaru, Y., Olson, S., Fleming, W., Finegold, M. & Grompe, M., Jan 2006, In : Molecular Therapy. 13, 1, p. 49-58 10 p.

Research output: Contribution to journalArticle

Homogentisic Acid
Proximal Kidney Tubule
Genetic Selection
Epithelial Cells
Regeneration
3 Citations (Scopus)

Modification of the Woodruff-Stamper assay demonstrates binding of Toxoplasma gondii tachyzoites to retinal vascular endothelium

Chipps, T. J., Streeter, P., Franc, D. T., Neumeyer, K., Planck, S., Rosenbaum, J. J. & Smith, J. R., May 30 2006, In : Journal of Immunological Methods. 312, 1-2, p. 209-213 5 p.

Research output: Contribution to journalArticle

Retinal Vessels
Toxoplasma
Vascular Endothelium
Retina
Endothelium
13 Citations (Scopus)

Mouse models of hematopoietic engraftment: Limitations of transgenic green fluorescent protein strains and a high-performance liquid chromatography approach to analysis of erythroid chimerism

Spangrude, G. J., Cho, S., Guedelhoefer, O., VanWoerkom, R. C. & Fleming, W., 2006, In : Stem Cells. 24, 9, p. 2045-2051 7 p.

Research output: Contribution to journalArticle

Chimerism
Green Fluorescent Proteins
High Pressure Liquid Chromatography
Bone Marrow Transplantation
Transgenic Mice
54 Citations (Scopus)

Mutation of an upstream cleavage site in the BMP4 prodomain leads to tissue-specific loss of activity

Goldman, D., Hackenmiller, R., Nakayama, T., Sopory, S., Wong, C., Kulessa, H. & Christian, J. L., May 2006, In : Development. 133, 10, p. 1933-1942 10 p.

Research output: Contribution to journalArticle

Mutation
Allantois
Xenopus
Point Mutation
Germ Cells
145 Citations (Scopus)

Myeloid lineage progenitors give rise to vascular endothelium

Bailey, A. S., Willenbring, H., Jiang, S., Anderson, D. A., Schroeder, D. A., Wong, M., Grompe, M. & Fleming, W., Aug 29 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 35, p. 13156-13161 6 p.

Research output: Contribution to journalArticle

Vascular Endothelium
Endothelial Cells
Hematopoietic System
Bone Marrow
Blood Vessels
26 Citations (Scopus)

Rapid 1-hour transduction of whole bone marrow leads to long-term repopulation of murine recipients with lentivirus-modified hematopoietic stem cells

Kurre, P., Anandakumar, P. & Kiem, H. P., Feb 2006, In : Gene Therapy. 13, 4, p. 369-373 5 p.

Research output: Contribution to journalArticle

Lentivirus
Hematopoietic Stem Cells
Bone Marrow
Cytokines
HIV
30 Citations (Scopus)

Recombinant HLA-DP2 binds beryllium and tolerizes beryllium-specific pathogenic CD4+ T cells

Fontenot, A. P., Keizer, T. S., McCleskey, M., Mack, D. G., Meza-Romero, R., Huan, J., Edwards, D. M., Chou, Y. K., Vandenbark, A., Scott, B. & Burrows, G. G., Sep 15 2006, In : Journal of Immunology. 177, 6, p. 3874-3883 10 p.

Research output: Contribution to journalArticle

Beryllium
T-Lymphocytes
Berylliosis
Lung
Peptides
2005
37 Citations (Scopus)

Diagnosis and treatment of children with aplastic anemia

Kurre, P., Johnson, F. L. & Deeg, H. J., Oct 2005, In : Pediatric Blood and Cancer. 45, 6, p. 770-780 11 p.

Research output: Contribution to journalArticle

Aplastic Anemia
Hematopoietic Stem Cell Transplantation
Immunosuppressive Agents
Tissue Donors
Therapeutics
15 Citations (Scopus)

Donor marker infidelity in transgenic hematopoietic stem cells

Anderson, D. A., Wu, Y., Jiang, S., Zhang, X., Streeter, P., Spangrude, G. J., Archer, D. R. & Fleming, W., May 2005, In : Stem Cells. 23, 5, p. 638-643 6 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Stem Cells
Myeloid Cells
Transgenes
Transgenic Mice
2 Citations (Scopus)

Endothelial cell-specific markers: Going . . . going . . . gone

Fleming, W., Aug 1 2005, In : Blood. 106, 3, p. 769 1 p.

Research output: Contribution to journalArticle

Endothelial cells
8 Citations (Scopus)

Lipooligosaccharide-independent alteration of cellular homeostasis in Neisseria meningitidis-infected epithelial cells

Bonnah, R., Hoelter, J., Steeghs, L., Enns, C., So, M. & Muckenthaler, M. U., Jun 2005, In : Cellular Microbiology. 7, 6, p. 869-885 17 p.

Research output: Contribution to journalArticle

Neisseria meningitidis
Homeostasis
Epithelial Cells
Iron
Transferrin Receptors
10 Citations (Scopus)

Rationally designed mutations convert complexes of human recombinant T cell receptor ligands into monomers that retain biological activity

Huan, J., Meza-Romero, R., Mooney, J. L., Chou, Y. K., Edwards, D. M., Rich, C., Link, J., Vandenbark, A., Bourdette, D., Bächinger, H. P. & Burrows, G. G., Jan 2005, In : Journal of Chemical Technology and Biotechnology. 80, 1, p. 2-12 11 p.

Research output: Contribution to journalArticle

T-cells
T-Cell Antigen Receptor
Bioactivity
peptide
Peptides
34 Citations (Scopus)

Treatment of passive experimental autoimmune encephalomyelitis in SJL mice with a recombinant TCR ligand induces IL-13 and prevents axonal injury

Offner, H., Subramanian, S., Wang, C., Afentoulis, M., Vandenbark, A., Huan, J. & Burrows, G. G., Sep 15 2005, In : Journal of Immunology. 175, 6, p. 4103-4111 9 p.

Research output: Contribution to journalArticle

Interleukin-13
Autoimmune Experimental Encephalomyelitis
Ligands
Cytokines
Wounds and Injuries
2004
9 Citations (Scopus)

CD25 expression distinguishes functionally distinct alloreactive CD4+ CD134+ (OX40+) T-cell subsets in acute graft-versus-host disease

Streeter, P., Zhang, X., Tittle, T. V., Schön, C. N., Weinberg, A. D. & Maziarz, R., May 2004, In : Biology of Blood and Marrow Transplantation. 10, 5, p. 298-309 12 p.

Research output: Contribution to journalArticle

T-Lymphocyte Subsets
Graft vs Host Disease
Isoantigens
Interleukin-2
T-Lymphocytes
23 Citations (Scopus)

Expression of epithelial cell iron-related genes upon infection by Neisseria meningitidis

Bonnah, R., Muckenthaler, M. U., Carlson, H., Minana, B., Enns, C., Hentze, M. W. & So, M., May 2004, In : Cellular Microbiology. 6, 5, p. 473-484 12 p.

Research output: Contribution to journalArticle

Neisseria meningitidis
Transferrin Receptors
Iron
Genes
Epithelial Cells
42 Citations (Scopus)

Monomeric Recombinant TCR Ligand Reduces Relapse Rate and Severity of Experimental Autoimmune Encephalomyelitis in SJL/J Mice through Cytokine Switch

Huan, J., Subramanian, S., Jones, R., Rich, C., Link, J., Mooney, J., Bourdette, D., Vandenbark, A., Burrows, G. G. & Offner, H., Apr 1 2004, In : Journal of Immunology. 172, 7, p. 4556-4566 11 p.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Cytokines
Ligands
Recurrence
Peptides
338 Citations (Scopus)

Myelomonocytic cells are sufficient for therapeutic cell fusion in liver

Willenbring, H., Bailey, A. S., Foster, M., Akkari, Y., Dorrell, C., Olson, S., Finegold, M., Fleming, W. & Grompe, M., Jul 2004, In : Nature Medicine. 10, 7, p. 744-748 5 p.

Research output: Contribution to journalArticle

Cell Fusion
Liver
Hepatocytes
Bone
Fusion reactions
75 Citations (Scopus)

PECAM-1 is expressed on hematopoietic stem cells throughout ontogeny and identifies a population of erythroid progenitors

Baumann, C. I., Bailey, A. S., Li, W., Ferkowicz, M. J., Yoder, M. C. & Fleming, W., Aug 15 2004, In : Blood. 104, 4, p. 1010-1016 7 p.

Research output: Contribution to journalArticle

CD31 Antigens
Hematopoietic Stem Cells
Stem cells
Bone
Population
33 Citations (Scopus)

Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells

Huan, J., Streicher, J. M., Bleyle, L. A. & Koop, D., Sep 15 2004, In : Toxicology and Applied Pharmacology. 199, 3, p. 332-343 12 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2B1
Cytochrome P-450 CYP2E1
Proteasome Endopeptidase Complex
Tetracycline
HeLa Cells
13 Citations (Scopus)

T-cell hybridoma specific for myelin oligodendrocyte glycoprotein-35-55 peptide produced from HLA-DRB1*1501-transgenic mice

Chou, Y. K., Culbertson, N., Rich, C., LaTocha, D., Buenafe, A. C., Huan, J., Link, J., Wands, J. M., Born, W. K., Offner, H., Bourdette, D., Burrows, G. G. & Vandenbark, A., Sep 1 2004, In : Journal of Neuroscience Research. 77, 5, p. 670-680 11 p.

Research output: Contribution to journalArticle

HLA-DRB1 Chains
Hybridomas
Transgenic Mice
T-Lymphocytes
Peptides
47 Citations (Scopus)

Toll-like receptor 4 and CD14 expression in human ciliary body and TLR-4 in human iris endothelial cells

Brito, B. E., Zamora, D. O., Bonnah, R., Pan, Y., Planck, S. & Rosenbaum, J. J., Aug 2004, In : Experimental Eye Research. 79, 2, p. 203-208 6 p.

Research output: Contribution to journalArticle

Ciliary Body
Toll-Like Receptor 4
Iris
Human Body
Endothelial Cells
216 Citations (Scopus)

Transplanted adult hematopoietic stems cells differentiate into functional endothelial cells

Bailey, A. S., Jiang, S., Afentoulis, M., Baumann, C. I., Schroeder, D. A., Olson, S., Wong, M. & Fleming, W., Jan 1 2004, In : Blood. 103, 1, p. 13-19 7 p.

Research output: Contribution to journalArticle

Adult Stem Cells
Endothelial cells
Hematopoietic Stem Cells
Stem cells
Endothelial Cells
115 Citations (Scopus)

Transplanted human bone marrow contributes to vascular endothelium

Jiang, S., Walker, L., Afentoulis, M., Anderson, D. A., Jauron-Mills, L., Corless, C. & Fleming, W., Nov 30 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 48, p. 16891-16896 6 p.

Research output: Contribution to journalArticle

Vascular Endothelium
Endothelial Cells
Bone Marrow
Hematopoietic Stem Cells
Tissue Donors
2003
13 Citations (Scopus)

Activation of the G-CSF and Flt-3 receptors protects hematopoietic stem cells from lethal irradiation

Streeter, P., Dudley, L. Z. & Fleming, W., Nov 2003, In : Experimental Hematology. 31, 11, p. 1119-1125 7 p.

Research output: Contribution to journalArticle

Granulocyte Colony-Stimulating Factor
Hematopoietic Stem Cells
Granulocyte Colony-Stimulating Factor Receptors
Cytokines
Hematopoiesis
61 Citations (Scopus)

Converging roads: Evidence for an adult hemangioblast

Bailey, A. S. & Fleming, W., Nov 2003, In : Experimental Hematology. 31, 11, p. 987-993 7 p.

Research output: Contribution to journalArticle

Hemangioblasts
Blood Vessels
Hematopoietic Stem Cells
Bone Marrow
Hematopoietic System
43 Citations (Scopus)

Recombinant TCR ligand induces early TCR signaling and a unique pattern of downstream activation

Wang, C., Mooney, J. L., Meza-Romero, R., Chou, Y. K., Huan, J., Vandenbark, A., Offner, H. & Burrows, G. G., Aug 15 2003, In : Journal of Immunology. 171, 4, p. 1934-1940 7 p.

Research output: Contribution to journalArticle

Ligands
T-Lymphocytes
Peptides
Extracellular Signal-Regulated MAP Kinases
Interleukin-2
70 Citations (Scopus)

Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice

Vandenbark, A., Rich, C., Mooney, J., Zamora, A., Wang, C., Huan, J., Fugger, L., Offner, H., Jones, R. & Burrows, G. G., Jul 1 2003, In : Journal of Immunology. 171, 1, p. 127-133 7 p.

Research output: Contribution to journalArticle

HLA-DR2 Antigen
Autoimmune Experimental Encephalomyelitis
Transgenic Mice
Ligands
Peptides
2002
37 Citations (Scopus)

Adult blood vessels restore host hematopoiesis following lethal irradiation

Montfort, M. J., Olivares, C. R., Mulcahy, J. M. & Fleming, W., 2002, In : Experimental Hematology. 30, 8, p. 950-956 7 p.

Research output: Contribution to journalArticle

Hematopoiesis
Blood Vessels
Stem Cells
Transplantation
Tunica Intima

Characterization of dendritic cells generated in vivo by an E. coli derived chimeric dual receptor agonist

Kahn, L. E., Doshi, P., McGarity, K. L., Yu, M., Bono, C. P., Lie, W. R., Rankin, A. M., Smidt, M. L., Streeter, P., Klein, B. K., Welply, J. K. & Woulfe, S. L., Dec 1 2002, In : Medical Science Monitor. 8, 12

Research output: Contribution to journalArticle

Dendritic Cells
Escherichia coli
Spleen
Leukocytes
Granulocyte Colony-Stimulating Factor Receptors
10 Citations (Scopus)

Toxic megacolon: A life-threatening complication of high-dose therapy and autologous stem cell transplantation among patients with AL amyloidosis

Hayes-Lattin, B., Curtin, P. T., Fleming, W., Leis, J. F., Stepan, D. E., Schubach, S. & Maziarz, R., Sep 2002, In : Bone Marrow Transplantation. 30, 5, p. 279-285 7 p.

Research output: Contribution to journalArticle

Toxic Megacolon
Stem Cell Transplantation
Amyloidosis
Immunoglobulin Light Chains
Autologous Transplantation
2001
19 Citations (Scopus)
fms-Like Tyrosine Kinase 3
Granulocyte Colony-Stimulating Factor Receptors
Hematopoietic Stem Cells
Protein-Tyrosine Kinases
Tissue Donors
2000
17 Citations (Scopus)

Alteration of epithelial cell transferrin-iron homeostasis by Neisseria meningitidis and Neisseria gonorrhoeae

Bonnah, R., Lee, S. W., Vasquez, B. L., Enns, C. & So, M., 2000, In : Cellular Microbiology. 2, 3, p. 207-218 12 p.

Research output: Contribution to journalArticle

Neisseria meningitidis
Neisseria gonorrhoeae
Transferrin
Homeostasis
Iron

Phase I/Ii study of combination high-dose therapy with busulfan, thiotepa, and total body irradiation (TBI) for the treatment of aggressive multiple myeloma

Leis, J. F., Hansen, K. S., Brunvand, M. W. & Fleming, W., 2000, In : Blood. 96, 11 PART II

Research output: Contribution to journalArticle

Thiotepa
Busulfan
Whole-Body Irradiation
Multiple Myeloma
Toxicity
1999
12 Citations (Scopus)

Administration of daniplestim and granulocyte colony-stimulating factor for the mobilization of hematopoietic progenitor cells in nonhuman primates

Fleming, W., Lankford-Turner, P., Turner, C. W., Wong, J., Strobert, E. & McKearn, J. P., 1999, In : Biology of Blood and Marrow Transplantation. 5, 1, p. 8-14 7 p.

Research output: Contribution to journalArticle

Granulocyte Colony-Stimulating Factor
Hematopoietic Stem Cells
Primates
Stem Cells
Interleukin-3 Receptors
2 Citations (Scopus)

Interactions in sheep between tall fescue ergot alkaloids and hepatotoxic carbon tetrachloride and senecio pyrrolizidine alkaloids

Debessai, W. T., Huan, J. & Cheeke, P. R., Jun 1999, In : Veterinary and Human Toxicology. 41, 3, p. 129-133 5 p.

Research output: Contribution to journalArticle

Ergot Alkaloids
Pyrrolizidine Alkaloids
ergot alkaloids
pyrrolizidine alkaloids
carbon tetrachloride