Nephrology & Hypertension

Research Output

2020

Diuretic Therapy for Patients With Heart Failure: JACC State-of-the-Art Review

Felker, G. M., Ellison, D. H., Mullens, W., Cox, Z. L. & Testani, J. M., Mar 17 2020, In : Journal of the American College of Cardiology. 75, 10, p. 1178-1195 18 p.

Research output: Contribution to journalReview article

Effect of Angiotensin II on ENaC in the Distal Convoluted Tubule and in the Cortical Collecting Duct of Mineralocorticoid Receptor Deficient Mice

Wu, P., Gao, Z. X., Zhang, D. D., Duan, X. P., Terker, A. S., Lin, D. H., Ellison, D. H. & Wang, W. H., Apr 7 2020, In : Journal of the American Heart Association. 9, 7, p. e014996

Research output: Contribution to journalArticle

Open Access

Hypertension-causing cullin 3 mutations disrupt COP9 signalosome binding

Cornelius, R. J., Yang, C. L. & Ellison, D. H., Jan 1 2020, In : American Journal of Physiology - Renal Physiology. 318, 1, p. F204-F208

Research output: Contribution to journalReview article

Potassium homeostasis and management of dyskalemia in kidney diseases: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Clase, C. M., Carrero, J. J., Ellison, D. H., Grams, M. E., Hemmelgarn, B. R., Jardine, M. J., Kovesdy, C. P., Kline, G. A., Lindner, G., Obrador, G. T., Palmer, B. F., Cheung, M., Wheeler, D. C., Winkelmayer, W. C., Pecoits-Filho, R., Ashuntantang, G. E., Bakker, S. J. L., Bakris, G. L., Bhandari, S., Burdmann, E. A. & 33 others, Campbell, K. L., Charytan, D. M., Clegg, D. J., Cuppari, L., Goldsmith, D., Hallan, S. I., He, J., Herzog, C. A., Hoenig, M. P., Hoorn, E. J., Leipziger, J. G., Leonberg-Yoo, A. K., Lerma, E. V., Lopez-Almaraz, J. E., Małyszko, J., Mann, J. F. E., Marklund, M., McDonough, A. A., Nagahama, M., Navaneethan, S. D., Pitt, B., Pochynyuk, O. M., Proença de Moraes, T., Rafique, Z., Robinson, B. M., Roger, S. D., Rossignol, P., Singer, A. J., Smyth, A., Sood, M. M., Walsh, M., Weir, M. R. & Wingo, C. S., Jan 2020, In : Kidney International. 97, 1, p. 42-61 20 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Tacrolimus-induced hypomagnesemia and hypercalciuria requires FKBP12 suggesting a role for calcineurin

Gratreak, B. D. K., Swanson, E. A., Lazelle, R. A., Jelen, S. K., Hoenderop, J., Bindels, R. J., Yang, C. L. & Ellison, D. H., Jan 1 2020, In : Physiological reports. 8, 1, e14316.

Research output: Contribution to journalArticle

Open Access

The acute kidney injury to chronic kidney disease transition in a mouse model of acute cardiorenal syndrome emphasizes the role of inflammation

Matsushita, K., Saritas, T., Eiwaz, M. B., McClellan, N., Coe, I., Zhu, W., Ferdaus, M. Z., Sakai, L. Y., McCormick, J. A. & Hutchens, M. P., Jan 2020, In : Kidney International. 97, 1, p. 95-105 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

WNK bodies cluster WNK4 and SPAK/OSR1 to promote NCC activation in hypokalemia

Thomson, M. N., Cuevas, C. A., Bewarder, T. M., Dittmayer, C., Miller, L. N., Si, J., Cornelius, R. J., Su, X. T., Yang, C. L., McCormick, J. A., Hadchouel, J., Ellison, D. H., Bachmann, S. & Mutig, K., Jan 1 2020, In : American Journal of Physiology - Renal Physiology. 318, 1, p. F216-F228

Research output: Contribution to journalArticle

2019

A caveat to the MISSION Act: Perspective from a Veterans Administration transplant center

Lockridge, J., Norman, D., Rehman, S., Scott, D., Maynard, E., Bowers, D., Siegman, I. & Martin, K., Jan 1 2019, (Accepted/In press) In : American Journal of Transplantation.

Research output: Contribution to journalLetter

Adipocyte deficiency of ACE2 increases systolic blood pressures of obese female C57BL/6 mice

Shoemaker, R., Tannock, L. R., Su, W., Gong, M., Gurley, S. B., Thatcher, S. E., Yiannikouris, F., Ensor, C. M. & Cassis, L. A., Sep 4 2019, In : Biology of sex differences. 10, 1, 45.

Research output: Contribution to journalArticle

Open Access

Altered vertebral and femoral bone structure in juvenile offspring of microswine subject to maternal low protein nutritional challenge

Lanham, S. A., DuPriest, E., Kupfer, P., Cooper, C., Bagby, S. P. & Oreffo, R. O. C., Jun 2019, In : Physiological reports. 7, 11, e14081.

Research output: Contribution to journalArticle

Open Access

Animal Models of Hypertension: A Scientific Statement From the American Heart Association

Lerman, L. O., Kurtz, T. W., Touyz, R. M., Ellison, D. H., Chade, A. R., Crowley, S. D., Mattson, D. L., Mullins, J. J., Osborn, J., Eirin, A., Reckelhoff, J. F., Iadecola, C. & Coffman, T. M., Jun 1 2019, In : Hypertension (Dallas, Tex. : 1979). 73, 6, p. e87-e120

Research output: Contribution to journalArticle

Open Access

Clinical pharmacology in diuretic use

Ellison, D., Aug 7 2019, In : Clinical Journal of the American Society of Nephrology. 14, 8, p. 1248-1257 10 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension

Agbor, L. N., Nair, A. R., Wu, J., Lu, K. T., Davis, D. R., Keen, H. L., Quelle, F. W., McCormick, J. J., Singer, J. D. & Sigmund, C. D., Jul 25 2019, In : JCI Insight. 4, 14, e129793.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Cullin-Ring ubiquitin ligases in kidney health and disease

Cornelius, R. J., Ferdaus, M. Z., Nelson, J. W. & Mccormick, J. A., Sep 1 2019, In : Current opinion in nephrology and hypertension. 28, 5, p. 490-497 8 p.

Research output: Contribution to journalReview article

1 Scopus citations

Dialysis initiation, modality choice, access, and prescription: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Chan, C. T., Blankestijn, P. J., Dember, L. M., Gallieni, M., Harris, D. C. H., Lok, C. E., Mehrotra, R., Stevens, P. E., Wang, A. Y. M., Cheung, M., Wheeler, D. C., Winkelmayer, W. C., Pollock, C. A., Abu-Alfa, A. K., Bargman, J. M., Bleyer, A. J., Brown, E. A., Davenport, A., Davies, S. J., Finkelstein, F. O. & 53 others, Flythe, J. E., Goffin, E., Golper, T. A., Gómez, R., Hamano, T., Hecking, M., Heimbürger, O., Hole, B., Hothi, D. K., Ikizler, T. A., Isaka, Y., Iseki, K., Jha, V., Kawanishi, H., Kerr, P. G., Komenda, P., Kovesdy, C. P., Lacson, E., Laville, M., Lee, J. P., Lerma, E. V., Levin, N. W., Lichodziejewska-Niemierko, M., Liew, A., Lindley, E., Lockridge, R. S., Madero, M., Massy, Z. A., McCann, L., Meyer, K. B., Morton, R. L., Nadeau-Fredette, A. C., Okada, H., Perez, J., Perl, J., Polkinghorne, K. R., Riella, M. C., Robinson, B. M., Rocco, M. V., Rosansky, S. J., Rotmans, J. I., Fernanda Slon Roblero, M., Tangri, N., Tonelli, M., Tong, A., Tsukamoto, Y., Tungsanga, K., Vachharajani, T. J., van Loon, I., Watnick, S., Weiner, D. E., Wilkie, M. & Zakharova, E., Jul 2019, In : Kidney International. 96, 1, p. 37-47 11 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis

Saritas, T., Cuevas, C. A., Ferdaus, M. Z., Kuppe, C., Kramann, R., Moeller, M. J., Floege, J., Singer, J. D. & McCormick, J. J., Dec 1 2019, In : Scientific Reports. 9, 1, 4596.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Enemy Action in the Distal Convoluted Tubule

Ellison, D. & Lin, S. H., Aug 1 2019, In : Journal of the American Society of Nephrology : JASN. 30, 8, p. 1345-1348 4 p.

Research output: Contribution to journalEditorial

1 Scopus citations

From the Outside In: Biological Mechanisms Linking Social and Environmental Exposures to Chronic Disease and to Health Disparities

Bagby, S., Martin, D., Chung, S. T. & Rajapakse, N., Jan 1 2019, In : American Journal of Public Health. 109, S1, p. S56-S63

Research output: Contribution to journalArticle

Global Health Training Opportunities in North American Nephrology Fellowships

International Society of Nephrology North American and Caribbean Regional Board, Jul 1 2019, In : Kidney International Reports. 4, 7, p. 904-907 4 p.

Research output: Contribution to journalEditorial

Open Access

Heritability and individuality of the plasma sodium concentration: a twin study in the United States veteran population

Timmons, A. K., Korpak, A. M., Tan, J., Moore, K. P., Liu, C. H., Forsberg, C. W., Goldberg, J., Smith, N. L. & Cohen, D., Jun 1 2019, In : American journal of physiology. Renal physiology. 316, 6, p. F1114-F1123

Research output: Contribution to journalArticle

Kir4.1/Kir5.1 in the DCT plays a role in the regulation of renal K + excretion

Su, X. T., Ellison, D. & Wang, W. H., Mar 1 2019, In : American journal of physiology. Renal physiology. 316, 3, p. F582-F586

Research output: Contribution to journalArticle

6 Scopus citations

Mechanistic insights into loop diuretic responsiveness in heart failure

Ellison, D. H., May 7 2019, In : Clinical Journal of the American Society of Nephrology. 14, 5, p. 650-652 3 p.

Research output: Contribution to journalEditorial

Mg2+ restriction downregulates NCC through NEDD4-2 and prevents its activation by hypokalemia

Ferdaus, M. Z., Mukherjee, A., Nelson, J. W., Blatt, P. J., Miller, L. N., Terker, A. S., Staub, O., Lin, D. H. & McCormick, J. A., Oct 1 2019, In : American journal of physiology. Renal physiology. 317, 4, p. F825-F838

Research output: Contribution to journalArticle

Optical clearing and imaging of immunolabeled kidney tissue

Saritas, T., Puelles, V. G., Su, X. T., Ellison, D. & Kramann, R., Jul 1 2019, In : Journal of Visualized Experiments. 2019, 149, e60002.

Research output: Contribution to journalArticle

Optical tissue clearing and immunolabeling in kidney research

Su, X. T., Saritas, T. & Ellison, D. H., 2019, Methods in Cell Biology. Weimbs, T. (ed.). Academic Press Inc., p. 31-41 11 p. (Methods in Cell Biology; vol. 154).

Research output: Chapter in Book/Report/Conference proceedingChapter

Patients with hypokalemia develop WNK bodies in the distal convoluted tubule of the kidney

Thomson, M. N., Schneider, W., Mutig, K., Ellison, D., Kettritz, R. & Bachmann, S., Feb 1 2019, In : American journal of physiology. Renal physiology. 316, 2, p. F292-F300

Research output: Contribution to journalArticle

Renal-Tubule Epithelial Cell Nomenclature for Single-Cell RNA-Sequencing Studies

Chen, L., Clark, J. Z., Nelson, J. W., Kaissling, B., Ellison, D. & Knepper, M. A., Aug 1 2019, In : Journal of the American Society of Nephrology : JASN. 30, 8, p. 1358-1364 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2 Scopus citations

Salt-sensitive transcriptome of isolated kidney distal tubule cells

Swanson, E. A., Nelson, J. W., Jeng, S., Erspamer, K. J., Yang, C. L., McWeeney, S. & Ellison, D. H., Apr 2019, In : Physiological genomics. 51, 4, p. 125-135 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Separate and interacting effects of the endogenous circadian system and behaviors on plasma aldosterone in humans

Thosar, S. S., Rueda, J., Berman, A. M., Lasarev, M. R., Herzig, M. X., Clemons, N. A., Roberts, S. A., Bowles, N. P., Emens, J., Ellison, D. & Shea, S., Feb 1 2019, In : American journal of physiology. Regulatory, integrative and comparative physiology. 316, 2, p. R157-R164

Research output: Contribution to journalArticle

1 Scopus citations

Serum Bicarbonate as a Surrogate for pH in Hemodialysis: A Pilot Study

Woodell, T. B., Rifkin, D. E., Ellison, D. H., Negoianu, D. & Weiss, J. W., Jan 1 2019, (Accepted/In press) In : Kidney Medicine.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Time for reform in transplant program–specific reporting: AST/ASTS transplant metrics taskforce

the AST/ASTS Transplant Metrics Taskforce, Jul 1 2019, In : American Journal of Transplantation. 19, 7, p. 1888-1895 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Why are physicians so confused about acute heart failure?

Ellison, D. H., Dec 12 2019, In : New England Journal of Medicine. 381, 24, p. 2374-2375 2 p.

Research output: Contribution to journalLetter

WNK4 limits distal calcium losses following acute furosemide treatment

Ferdaus, M. Z., Gratreak, B. D. K., Miller, L., Si, J., McCormick, J. A., Yang, C. L., Ellison, D. H. & Terker, A. S., Sep 1 2019, In : Physiological reports. 7, 17, e14195.

Research output: Contribution to journalArticle

Open Access
2018

C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity

Murillo-de-Ozores, A. R., Rodríguez-Gama, A., Bazúa-Valenti, S., Leyva-Ríos, K., Vázquez, N., Pacheco-Álvarez, D., De La Rosa-Velázquez, I. A., Wengi, A., Stone, K. L., Zhang, J., Loffing, J., Lifton, R. P., Yang, C-L., Ellison, D., Gamba, G. & Castañeda-Bueno, M., Jan 1 2018, In : Journal of Biological Chemistry. 293, 31, p. 12209-12221 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension

Cornelius, R. J., Zhang, C., Erspamer, K. J., Agbor, L. N., Sigmund, C. D., Singer, J. D., Yang, C. L. & Ellison, D. H., Oct 1 2018, In : American journal of physiology. Renal physiology. 315, 4, p. F1006-F1018

Research output: Contribution to journalArticle

5 Scopus citations

Effects of postweaning calorie restriction on accelerated growth and adiponectin in nutritionally programmed microswine offspring

Dupriest, E. A., Lin, B., Kupfer, P., Sekiguchi, K., Bhusari, A., Quackenbush, A., Celebic, A., Morgan, T., Purnell, J. & Bagby, S., Aug 20 2018, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 315, 2, p. R354-R368

Research output: Contribution to journalArticle

1 Scopus citations

Elephant in the room

Hartung, D. M., Johnston, K., Cohen, D., Nguyen, T., Deodhar, A. A. & Bourdette, D., Jan 23 2018, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

1 Scopus citations

Endothelial transcriptomics reveals activation of fibrosis-related pathways in hypertension

Nelson, J. W., Ferdaus, M. Z., McCormick, J. J., Minnier, J., Kaul, S., Ellison, D. & Barnes, A., Feb 1 2018, In : Physiological Genomics. 50, 2, p. 104-116 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

In reply

Hartung, D. M., Bourdette, D. & Cohen, D., Apr 1 2018, In : JAMA Internal Medicine. 178, 4, p. 583-584 2 p.

Research output: Contribution to journalLetter

Kidney Biopsy Adequacy: A Metric-based Study

Ferrer, G., Andeen, N., Lockridge, J., Norman, D., Foster, B., Houghton, D. & Troxell, M., Jun 5 2018, (Accepted/In press) In : American Journal of Surgical Pathology.

Research output: Contribution to journalArticle

Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC

Argaiz, E. R., Chavez-Canales, M., Ostrosky-Frid, M., Rodríguez-Gama, A., Vázquez, N., Gonzalez-Rodriguez, X., Garcia-Valdes, J., Hadchouel, J., Ellison, D. & Gamba, G., Sep 6 2018, In : American Journal of Physiology - Renal Physiology. 315, 3, p. F734-F745

Research output: Contribution to journalArticle

10 Scopus citations

Mechanisms and controversies in mutant Cul3-mediated familial hyperkalemic hypertension

Ferdaus, M. Z. & McCormick, J. J., Jan 1 2018, In : American Journal of Physiology - Renal Physiology. 314, 5, p. F915-F920

Research output: Contribution to journalArticle

2 Scopus citations

Optical Clearing in the Kidney Reveals Potassium-Mediated Tubule Remodeling

Saritas, T., Puelles, V. G., Su, X. T., McCormick, J. J., Welling, P. A. & Ellison, D., Dec 4 2018, In : Cell Reports. 25, 10, p. 2668-2675.e3

Research output: Contribution to journalArticle

8 Scopus citations

Potassium intake modulates the thiazide-sensitive sodium-chloride cotransporter (NCC) activity via the Kir4.1 potassium channel

Wang, M. X., Cuevas, C. A., Su, X. T., Wu, P., Gao, Z. X., Lin, D. H., McCormick, J. J., Yang, C-L., Wang, W. H. & Ellison, D., Jan 1 2018, (Accepted/In press) In : Kidney International.

Research output: Contribution to journalArticle

27 Scopus citations

Renal COP9 signalosome deficiency alters CUL3-KLHL3-WNK signaling pathway

Cornelius, R. J., Si, J., Cuevas, C. A., Nelson, J. W., Gratreak, B. D. K., Pardi, R., Yang, C-L. & Ellison, D., Nov 1 2018, In : Journal of the American Society of Nephrology. 29, 11, p. 2627-2640 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

Renal tubular ACE-mediated tubular injury is the major contributor to microalbuminuria in early diabetic nephropathy

Eriguchi, M., Lin, M., Yamashita, M., Zhao, T. V., Khan, Z., Bernstein, E. A., Gurley, S. B., Gonzalez-Villalobos, R. A., Bernstein, K. E. & Giani, J. F., Apr 2018, In : American Journal of Physiology - Renal Physiology. 314, 4, p. F531-F542

Research output: Contribution to journalArticle

8 Scopus citations

Role of WNK4 and kidney-specific WNK1 in mediating the effect of high dietary K+ intake on ROMK channel in the distal convoluted tubule

Wu, P., Gao, Z. X., Su, X. T., Ellison, D. H., Hadchouel, J., Teulon, J. & Wang, W. H., Aug 2018, In : American Journal of Physiology - Renal Physiology. 315, 2, p. F223-F230

Research output: Contribution to journalArticle

2 Scopus citations

The Calcium-Sensing Receptor Increases Activity of the Renal NCC through the WNK4-SPAK Pathway

Bazúa-Valenti, S., Rojas-Vega, L., Castañeda-Bueno, M., Barrera-Chimal, J., Bautista, R., Cervantes-Pérez, L. G., Vázquez, N., Plata, C., Murillo-de-Ozores, A. R., González-Mariscal, L., Ellison, D. H., Riccardi, D., Bobadilla, N. A. & Gamba, G., Jul 2018, In : Journal of the American Society of Nephrology. 29, 7, p. 1838-1848 11 p.

Research output: Contribution to journalArticle

7 Scopus citations