Nephrology & Hypertension

Research Output 1977 2019

2019

A caveat to the MISSION Act: Perspective from a Veterans Administration transplant center

Lockridge, J., Norman, D., Rehman, S., Scott, D., Maynard, E., Bowers, D., Siegman, I. & Martin, K., Jan 1 2019, (Accepted/In press) In : American Journal of Transplantation.

Research output: Contribution to journalLetter

United States Department of Veterans Affairs
Health Services Research
Transplants

Adipocyte deficiency of ACE2 increases systolic blood pressures of obese female C57BL/6 mice

Shoemaker, R., Tannock, L. R., Su, W., Gong, M., Gurley, S., Thatcher, S. E., Yiannikouris, F., Ensor, C. M. & Cassis, L. A., Sep 4 2019, In : Biology of Sex Differences. 10, 1, 45.

Research output: Contribution to journalArticle

Open Access
hypertension
Inbred C57BL Mouse
Adipocytes
Blood Pressure
Obesity

Altered vertebral and femoral bone structure in juvenile offspring of microswine subject to maternal low protein nutritional challenge

Lanham, S. A., DuPriest, E., Kupfer, P., Cooper, C., Bagby, S. & Oreffo, R. O. C., Jun 1 2019, In : Physiological Reports. 7, 11, e14081.

Research output: Contribution to journalArticle

Open Access
Thigh
Mothers
Bone and Bones
Femur
Proteins

Animal Models of Hypertension: A Scientific Statement From the American Heart Association

Lerman, L. O., Kurtz, T. W., Touyz, R. M., Ellison, D., Chade, A. R., Crowley, S. D., Mattson, D. L., Mullins, J. J., Osborn, J., Eirin, A., Reckelhoff, J. F., Iadecola, C. & Coffman, T. M., Jun 1 2019, In : Hypertension (Dallas, Tex. : 1979). 73, 6, p. e87-e120

Research output: Contribution to journalArticle

Open Access
Animal Models
Hypertension
Comorbidity
Chronic Disease
Research Design
1 Citation (Scopus)

Clinical pharmacology in diuretic use

Ellison, D., Aug 7 2019, In : Clinical Journal of the American Society of Nephrology. 14, 8, p. 1248-1257 10 p.

Research output: Contribution to journalArticle

Open Access
Cardio-Renal Syndrome
Kidney Tubules
Clinical Pharmacology
Diuresis
Nephrotic Syndrome

Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension

Agbor, L. N., Nair, A. R., Wu, J., Lu, K. T., Davis, D. R., Keen, H. L., Quelle, F. W., McCormick, J. J., Singer, J. D. & Sigmund, C. D., Jul 25 2019, In : JCI Insight. 4, 14, e129793.

Research output: Contribution to journalArticle

Open Access
Cullin Proteins
Smooth Muscle
Hypertension
Vascular Smooth Muscle
Vascular Stiffness

Cullin-Ring ubiquitin ligases in kidney health and disease

Cornelius, R. J., Ferdaus, M. Z., Nelson, J. W. & McCormick, J. J., Sep 1 2019, In : Current opinion in nephrology and hypertension. 28, 5, p. 490-497 8 p.

Research output: Contribution to journalArticle

Cullin Proteins
Kidney Diseases
Ligases
Ubiquitin
Health
1 Citation (Scopus)

Dialysis initiation, modality choice, access, and prescription: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Chan, C. T., Blankestijn, P. J., Dember, L. M., Gallieni, M., Harris, D. C. H., Lok, C. E., Mehrotra, R., Stevens, P. E., Wang, A. Y. M., Cheung, M., Wheeler, D. C., Winkelmayer, W. C., Pollock, C. A., Abu-Alfa, A. K., Bargman, J. M., Bleyer, A. J., Brown, E. A., Davenport, A., Davies, S. J., Finkelstein, F. O. & 53 others, Flythe, J. E., Goffin, E., Golper, T. A., Gómez, R., Hamano, T., Hecking, M., Heimbürger, O., Hole, B., Hothi, D. K., Ikizler, T. A., Isaka, Y., Iseki, K., Jha, V., Kawanishi, H., Kerr, P. G., Komenda, P., Kovesdy, C. P., Lacson, E., Laville, M., Lee, J. P., Lerma, E. V., Levin, N. W., Lichodziejewska-Niemierko, M., Liew, A., Lindley, E., Lockridge, R. S., Madero, M., Massy, Z. A., McCann, L., Meyer, K. B., Morton, R. L., Nadeau-Fredette, A. C., Okada, H., Perez, J., Perl, J., Polkinghorne, K. R., Riella, M. C., Robinson, B. M., Rocco, M. V., Rosansky, S. J., Rotmans, J. I., Fernanda Slon Roblero, M., Tangri, N., Tonelli, M., Tong, A., Tsukamoto, Y., Tungsanga, K., Vachharajani, T. J., van Loon, I., Watnick, S., Weiner, D. E., Wilkie, M. & Zakharova, E., Jul 1 2019, In : Kidney International. 96, 1, p. 37-47 11 p.

Research output: Contribution to journalArticle

Open Access
Kidney Diseases
Prescriptions
Dialysis
Patient Care Planning
Delivery of Health Care
2 Citations (Scopus)

Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis

Saritas, T., Cuevas, C. A., Ferdaus, M. Z., Kuppe, C., Kramann, R., Moeller, M. J., Floege, J., Singer, J. D. & McCormick, J. J., Dec 1 2019, In : Scientific Reports. 9, 1, 4596.

Research output: Contribution to journalArticle

Open Access
Cullin Proteins
Proximal Kidney Tubule
Ubiquitination
Fibrosis
Kidney

Enemy Action in the Distal Convoluted Tubule

Ellison, D. & Lin, S. H., Aug 1 2019, In : Journal of the American Society of Nephrology : JASN. 30, 8, p. 1345-1348 4 p.

Research output: Contribution to journalEditorial

Gitelman Syndrome
Distal Kidney Tubule
Cross-Sectional Studies
Insulin
Phenotype
1 Citation (Scopus)

From the Outside In: Biological Mechanisms Linking Social and Environmental Exposures to Chronic Disease and to Health Disparities

Bagby, S., Martin, D., Chung, S. T. & Rajapakse, N., Jan 1 2019, In : American Journal of Public Health. 109, S1, p. S56-S63

Research output: Contribution to journalArticle

Environmental Exposure
Chronic Disease
Health
Population
Biological Models

Global Health Training Opportunities in North American Nephrology Fellowships

International Society of Nephrology North American and Caribbean Regional Board, Jul 1 2019, In : Kidney International Reports. 4, 7, p. 904-907 4 p.

Research output: Contribution to journalEditorial

Open Access
Nephrology
Global Health

Heritability and individuality of the plasma sodium concentration: a twin study in the United States veteran population

Timmons, A. K., Korpak, A. M., Tan, J., Moore, K. P., Liu, C. H., Forsberg, C. W., Goldberg, J., Smith, N. L. & Cohen, D., Jun 1 2019, In : American journal of physiology. Renal physiology. 316, 6, p. F1114-F1123

Research output: Contribution to journalArticle

Twin Studies
Veterans
Individuality
Sodium
Population

Kir4.1/Kir5.1 in the DCT plays a role in the regulation of renal K + excretion

Su, X. T., Ellison, D. & Wang, W. H., Mar 1 2019, In : American journal of physiology. Renal physiology. 316, 3, p. F582-F586

Research output: Contribution to journalArticle

Potassium
Member 1 Solute Carrier Family 12
Angiotensin Type 2 Receptor
Bradykinin B2 Receptors
Inwardly Rectifying Potassium Channel
Sodium Potassium Chloride Symporter Inhibitors
Furosemide
Diuretics
Heart Failure

Mg2+ restriction downregulates NCC through NEDD4-2 and prevents its activation by hypokalemia

Ferdaus, M. Z., Mukherjee, A., Nelson, J. W., Blatt, P. J., Miller, L. N., Terker, A. S., Staub, O., Lin, D. H. & McCormick, J. A., Oct 1 2019, In : American journal of physiology. Renal physiology. 317, 4, p. F825-F838

Research output: Contribution to journalArticle

Member 3 Solute Carrier Family 12
Hypokalemia
Magnesium
Potassium
Down-Regulation

Optical clearing and imaging of immunolabeled kidney tissue

Saritas, T., Puelles, V. G., Su, X. T., Ellison, D. & Kramann, R., Jul 1 2019, In : Journal of Visualized Experiments. 2019, 149, e60002.

Research output: Contribution to journalArticle

Optical Imaging
Antibodies
Tissue
Kidney
Imaging techniques

Optical tissue clearing and immunolabeling in kidney research

Su, X. T., Saritas, T. & Ellison, D., Jan 1 2019, Methods in Cell Biology. Weimbs, T. (ed.). Academic Press Inc., p. 31-41 11 p. (Methods in Cell Biology; vol. 154).

Research output: Chapter in Book/Report/Conference proceedingChapter

Kidney
Research
Refractometry
Equipment and Supplies
1 Citation (Scopus)

Patients with hypokalemia develop WNK bodies in the distal convoluted tubule of the kidney

Thomson, M. N., Schneider, W., Mutig, K., Ellison, D., Kettritz, R. & Bachmann, S., Feb 1 2019, In : American journal of physiology. Renal physiology. 316, 2, p. F292-F300

Research output: Contribution to journalArticle

Distal Kidney Tubule
Hypokalemia
Member 3 Solute Carrier Family 12
Phosphotransferases
Kidney

Renal-Tubule Epithelial Cell Nomenclature for Single-Cell RNA-Sequencing Studies

Chen, L., Clark, J. Z., Nelson, J. W., Kaissling, B., Ellison, D. & Knepper, M. A., Aug 1 2019, In : Journal of the American Society of Nephrology : JASN. 30, 8, p. 1358-1364 7 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Terminology
Epithelium
Epithelial Cells
Kidney
Nephrotic Syndrome
Adrenocorticotropic Hormone
Glucocorticoids
Kidney
Costs and Cost Analysis
1 Citation (Scopus)

Salt-sensitive transcriptome of isolated kidney distal tubule cells

Swanson, E. A., Nelson, J. W., Jeng, S., Erspamer, K. J., Yang, C-L., McWeeney, S. & Ellison, D., Apr 1 2019, In : Physiological genomics. 51, 4, p. 125-135 11 p.

Research output: Contribution to journalArticle

Distal Kidney Tubule
Aldosterone
Transcriptome
Salts
Diet
1 Citation (Scopus)

Separate and interacting effects of the endogenous circadian system and behaviors on plasma aldosterone in humans

Thosar, S. S., Rueda, J., Berman, A. M., Lasarev, M. R., Herzig, M. X., Clemons, N. A., Roberts, S. A., Bowles, N. P., Emens, J., Ellison, D. & Shea, S., Feb 1 2019, In : American journal of physiology. Regulatory, integrative and comparative physiology. 316, 2, p. R157-R164

Research output: Contribution to journalArticle

Aldosterone
Sleep
Wakefulness
Healthy Volunteers
Exercise
1 Citation (Scopus)

Time for reform in transplant program–specific reporting: AST/ASTS transplant metrics taskforce

the AST/ASTS Transplant Metrics Taskforce, Jul 1 2019, In : American Journal of Transplantation. 19, 7, p. 1888-1895 8 p.

Research output: Contribution to journalArticle

Graft Survival
Transplants
Uncertainty
Registries
United States Dept. of Health and Human Services

WNK4 limits distal calcium losses following acute furosemide treatment

Ferdaus, M. Z., Gratreak, B. D. K., Miller, L., Si, J., McCormick, J. J., Yang, C-L., Ellison, D. & Terker, A. S., Sep 1 2019, In : Physiological reports. 7, 17, p. e14195

Research output: Contribution to journalArticle

Open Access
Furosemide
Calcium
Nephrons
Extremities
Diet
2018
1 Citation (Scopus)

C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity

Murillo-de-Ozores, A. R., Rodríguez-Gama, A., Bazúa-Valenti, S., Leyva-Ríos, K., Vázquez, N., Pacheco-Álvarez, D., De La Rosa-Velázquez, I. A., Wengi, A., Stone, K. L., Zhang, J., Loffing, J., Lifton, R. P., Yang, C-L., Ellison, D., Gamba, G. & Castañeda-Bueno, M., Jan 1 2018, In : Journal of Biological Chemistry. 293, 31, p. 12209-12221 13 p.

Research output: Contribution to journalArticle

Protein Phosphatase 1
Phosphotransferases
Kidney
Binding Sites
Member 3 Solute Carrier Family 12
2 Citations (Scopus)

Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension

Cornelius, R. J., Zhang, C., Erspamer, K. J., Agbor, L. N., Sigmund, C. D., Singer, J. D., Yang, C-L. & Ellison, D., Oct 1 2018, In : American journal of physiology. Renal physiology. 315, 4, p. F1006-F1018

Research output: Contribution to journalArticle

Cullin Proteins
Ligases
Ubiquitin
Hypertension
Mutation
1 Citation (Scopus)

Effects of postweaning calorie restriction on accelerated growth and adiponectin in nutritionally programmed microswine offspring

Dupriest, E. A., Lin, B., Kupfer, P., Sekiguchi, K., Bhusari, A., Quackenbush, A., Celebic, A., Morgan, T., Purnell, J. & Bagby, S., Aug 20 2018, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 315, 2, p. R354-R368

Research output: Contribution to journalArticle

Adiponectin
Caloric Restriction
Growth
Proteins
Weaning
1 Citation (Scopus)

Elephant in the room

Hartung, D. M., Johnston, K., Cohen, D., Nguyen, T., Deodhar, A. A. & Bourdette, D., Jan 23 2018, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

Polymyositis
Dermatomyositis
Adrenal Cortex Hormones
3 Citations (Scopus)

Endothelial transcriptomics reveals activation of fibrosis-related pathways in hypertension

Nelson, J. W., Ferdaus, M. Z., McCormick, J. J., Minnier, J., Kaul, S., Ellison, D. & Barnes, A., Feb 1 2018, In : Physiological Genomics. 50, 2, p. 104-116 13 p.

Research output: Contribution to journalArticle

Fibrosis
Hypertension
Endothelial Cells
Blood Pressure
RNA Sequence Analysis

In reply

Hartung, D. M., Bourdette, D. & Cohen, D., Apr 1 2018, In : JAMA Internal Medicine. 178, 4, p. 583-584 2 p.

Research output: Contribution to journalLetter

Kidney Biopsy Adequacy: A Metric-based Study

Ferrer, G., Andeen, N., Lockridge, J., Norman, D., Foster, B., Houghton, D. & Troxell, M., Jun 5 2018, (Accepted/In press) In : American Journal of Surgical Pathology.

Research output: Contribution to journalArticle

Kidney
Biopsy
Microscopy
Light
Fluorescence Microscopy
4 Citations (Scopus)

Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC

Argaiz, E. R., Chavez-Canales, M., Ostrosky-Frid, M., Rodríguez-Gama, A., Vázquez, N., Gonzalez-Rodriguez, X., Garcia-Valdes, J., Hadchouel, J., Ellison, D. & Gamba, G., Sep 6 2018, In : American Journal of Physiology - Renal Physiology. 315, 3, p. F734-F745

Research output: Contribution to journalArticle

Member 3 Solute Carrier Family 12
Lysine
Protein Isoforms
Kidney
Phosphotransferases

Mechanisms and controversies in mutant Cul3-mediated familial hyperkalemic hypertension

Ferdaus, M. Z. & McCormick, J. J., Jan 1 2018, In : American Journal of Physiology - Renal Physiology. 314, 5, p. F915-F920

Research output: Contribution to journalArticle

Cullin Proteins
Hypertension
Phosphotransferases
Mutation
Haploinsufficiency
6 Citations (Scopus)

Optical Clearing in the Kidney Reveals Potassium-Mediated Tubule Remodeling

Saritas, T., Puelles, V. G., Su, X. T., McCormick, J. J., Welling, P. A. & Ellison, D., Dec 4 2018, In : Cell Reports. 25, 10, p. 2668-2675.e3

Research output: Contribution to journalArticle

Potassium
Nephrons
Kidney
Nutrition
Microscopy
16 Citations (Scopus)

Potassium intake modulates the thiazide-sensitive sodium-chloride cotransporter (NCC) activity via the Kir4.1 potassium channel

Wang, M. X., Cuevas, C. A., Su, X. T., Wu, P., Gao, Z. X., Lin, D. H., McCormick, J. J., Yang, C-L., Wang, W. H. & Ellison, D., Jan 1 2018, (Accepted/In press) In : Kidney International.

Research output: Contribution to journalArticle

Member 3 Solute Carrier Family 12
Potassium Channels
Potassium
Dietary Potassium
Knockout Mice
2 Citations (Scopus)

Renal COP9 signalosome deficiency alters CUL3-KLHL3-WNK signaling pathway

Cornelius, R. J., Si, J., Cuevas, C. A., Nelson, J. W., Gratreak, B. D. K., Pardi, R., Yang, C-L. & Ellison, D., Nov 1 2018, In : Journal of the American Society of Nephrology. 29, 11, p. 2627-2640 14 p.

Research output: Contribution to journalArticle

Cullin Proteins
Member 3 Solute Carrier Family 12
Kidney
Phenotype
Phosphotransferases

Role of WNK4 and kidney-specific WNK1 in mediating the effect of high dietary K+ intake on ROMK channel in the distal convoluted tubule

Wu, P., Gao, Z. X., Su, X. T., Ellison, D., Hadchouel, J., Teulon, J. & Wang, W. H., Aug 1 2018, In : American Journal of Physiology - Renal Physiology. 315, 2, p. F223-F230

Research output: Contribution to journalArticle

Lysine
Phosphotransferases
Kidney
Collecting Kidney Tubules
Kidney Tubules
3 Citations (Scopus)

The Calcium-Sensing Receptor Increases Activity of the Renal NCC through the WNK4-SPAK Pathway

Bazúa-Valenti, S., Rojas-Vega, L., Castañeda-Bueno, M., Barrera-Chimal, J., Bautista, R., Cervantes-Pérez, L. G., Vázquez, N., Plata, C., Murillo-de-Ozores, A. R., González-Mariscal, L., Ellison, D., Riccardi, D., Bobadilla, N. A. & Gamba, G., Jul 1 2018, In : Journal of the American Society of Nephrology. 29, 7, p. 1838-1848 11 p.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Kidney
N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine
Hypercalciuria
HEK293 Cells

The phosphoinositide phosphatase sac1 regulates cell shape and microtubule stability in the developing drosophila eye

Del Bel, L. M., Griffiths, N., Wilk, R., Wei, H. C., Blagoveshchenskaya, A., Burgess, J., Polevoy, G., Price, J. V., Mayinger, P. & Brill, J. A., Jun 1 2018, In : Development (Cambridge). 145, 11, dev151571.

Research output: Contribution to journalArticle

Cell Shape
Microtubules
Drosophila
Cell Adhesion Molecules
Drosophila melanogaster
4 Citations (Scopus)

Uncoupling proteins: Martin Klingenberg's contributions for 40 years

Echtay, K. S., Bienengraeber, M., Mayinger, P., Heimpel, S., Winkler, E., Druhmann, D., Frischmuth, K., Kamp, F. & Huang, S. G., Nov 1 2018, In : Archives of Biochemistry and Biophysics. 657, p. 41-55 15 p.

Research output: Contribution to journalReview article

Thermogenesis
Mammals
Neurology
Medical problems
Adrenergic Receptors
9 Citations (Scopus)

When to Stop Eculizumab in Complement-Mediated Thrombotic Microangiopathies

Olson, S. R., Lu, E., Sulpizio, E., Shatzel, J. J., Rueda, J. & Deloughery, T., Aug 1 2018, In : American Journal of Nephrology. 48, 2, p. 96-107 12 p.

Research output: Contribution to journalReview article

Thrombotic Microangiopathies
Complement Inactivating Agents
Recurrence
Hematopoietic Stem Cells
eculizumab
4 Citations (Scopus)

With no lysine kinase 4 modulates sodium potassium 2 chloride cotransporter activity in vivo

Terker, A. S., Castañeda-Bueno, M., Ferdaus, M. Z., Cornelius, R. J., Erspamer, K. J., Su, X. T., Miller, L. N., McCormick, J. J., Wang, W. H., Gamba, G., Yang, C-L. & Ellison, D., Oct 1 2018, In : American Journal of Physiology - Renal Physiology. 315, 4, p. F781-F790

Research output: Contribution to journalArticle

Sodium-Potassium-Chloride Symporters
Lysine
Phosphotransferases
Member 1 Solute Carrier Family 12
Knockout Mice
2017
2 Citations (Scopus)

A Case Report of Compound Heterozygous CYP24A1 Mutations Leading to Nephrolithiasis Successfully Treated with Ketoconazole

Davidson Peiris, E. & Wusirika, R., Dec 18 2017, (Accepted/In press) In : Case Reports in Nephrology and Dialysis. p. 167-171 5 p.

Research output: Contribution to journalArticle

Nephrolithiasis
Ketoconazole
Vitamin D
Mutation
Nephrocalcinosis
66 Citations (Scopus)

Benefits and Harms of Intensive Blood Pressure Treatment in Adults Aged 60 Years or Older: A Systematic Review and Meta-analysis

Weiss, J., Freeman, M., Low, A., Fu, R. R., Kerfoot, A., Paynter, R., Motu'apuaka, M., Kondo, K. & Kansagara, D., Mar 21 2017, In : Annals of Internal Medicine. 166, 6, p. 419-429 11 p.

Research output: Contribution to journalArticle

Meta-Analysis
Blood Pressure
United States Department of Veterans Affairs
Stroke
Guidelines
3 Citations (Scopus)

BK viremia surveillance and outcomes in simultaneous pancreas-kidney transplant recipients

Westphal, S. G., Lyden, E. R., Langewisch, E. & Miles, C. D., 2017, (Accepted/In press) In : Clinical Transplantation.

Research output: Contribution to journalArticle

Viremia
Pancreas
Allografts
Kidney
Immunosuppression
13 Citations (Scopus)

Calcineurin inhibitor cyclosporine A activates renal NA-K-CL cotransporters via local and systemic mechanisms

Blankenstein, K. I., Borschewski, A., Labes, R., Paliege, A., Boldt, C., McCormick, J. J., Ellison, D., Bader, M., Bachmann, S. & Mutig, K., Mar 1 2017, In : American Journal of Physiology - Renal Physiology. 312, 3, p. F489-F501

Research output: Contribution to journalArticle

Member 3 Solute Carrier Family 12
Arginine Vasopressin
Cyclosporine
Kidney
Calcineurin
2 Citations (Scopus)

Chronic kidney disease: A life course health development perspective

Brophy, P. D., Charlton, J. R., Carmody, J. B., Reidy, K. J., Harshman, L., Segar, J., Askenazi, D., Shoham, D. & Bagby, S., Jan 1 2017, Handbook of Life Course Health Development. Springer International Publishing, p. 375-401 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Chronic Renal Insufficiency
Disease
Health
health
medication
15 Citations (Scopus)

Compensatory distal reabsorption drives diuretic resistance in human heart failure

Rao, V. S., Planavsky, N., Hanberg, J. S., Ahmad, T., Brisco-Bacik, M. A., Wilson, F. P., Jacoby, D., Chen, M., Tang, W. H. W., Cherney, D. Z. I., Ellison, D. & Testani, J. M., Nov 1 2017, In : Journal of the American Society of Nephrology. 28, 11, p. 3414-3424 11 p.

Research output: Contribution to journalArticle

Diuretics
Heart Failure
Sodium Potassium Chloride Symporter Inhibitors
Sodium
Lithium
50 Citations (Scopus)

Diuretic treatment in heart failure

Ellison, D. & Felker, G. M., Nov 16 2017, In : New England Journal of Medicine. 377, 20, p. 1964-1975 12 p.

Research output: Contribution to journalReview article

Sodium Potassium Chloride Symporter Inhibitors
Acute Disease
Diuretics
Heart Failure
Kidney