Research Output 1969 2019

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2000
73 Citations (Scopus)

Resting B lymphocytes as APC for naive T lymphocytes: Dependence on CD40 ligand/CD40

Evans, D. E., Munks, M., Purkerson, J. M. & Parker, D., Jan 15 2000, In : Journal of Immunology. 164, 2, p. 688-697 10 p.

Research output: Contribution to journalArticle

CD40 Ligand
B-Lymphocytes
T-Lymphocytes
Cell Proliferation
Intercellular Adhesion Molecule-1
63 Citations (Scopus)

The extracellular domain of herpes simplex virus gE is sufficient for accumulation at cell junctions but not for cell-to-cell spread

Wisner, T., Brunetti, C., Dingwell, K. & Johnson, D., 2000, In : Journal of Virology. 74, 5, p. 2278-2287 10 p.

Research output: Contribution to journalArticle

intercellular junctions
herpes simplex
Intercellular Junctions
Simplexvirus
viruses
29 Citations (Scopus)

The structural basis of repertoire shift in an immune response to phosphocholine

Brown, M., Schumacher, M. A., Wiens, G. D., Brennan, R. G. & Rittenberg, M., Jun 19 2000, In : Journal of Experimental Medicine. 191, 12, p. 2101-2111 11 p.

Research output: Contribution to journalArticle

Phosphorylcholine
Mutation
Antibodies
Light
Proteins
20 Citations (Scopus)

Three-dimensional organization of retroviral capsid proteins on a lipid monolayer

McDermott, J., Mayo, K. & Barklis, E., Sep 8 2000, In : Journal of Molecular Biology. 302, 1, p. 121-133 13 p.

Research output: Contribution to journalArticle

Capsid Proteins
Lipids
Membranes
Moloney murine leukemia virus
Viral Structural Proteins
1999
30 Citations (Scopus)

Characterization of a targeting motif for a flagellar membrane protein in Leishmania enriettii

Snapp, E. L. & Landfear, S., Oct 8 1999, In : Journal of Biological Chemistry. 274, 41, p. 29543-29548 6 p.

Research output: Contribution to journalArticle

Leishmania enriettii
Membrane Proteins
Membranes
Amino Acids
Facilitative Glucose Transport Proteins
39 Citations (Scopus)

Cloning and functional expression of a gene encoding a P1 type nucleoside transporter from Trypanosoma brucei

Sanchez, M., Ullman, B., Landfear, S. & Carter, N., Oct 15 1999, In : Journal of Biological Chemistry. 274, 42, p. 30244-30249 6 p.

Research output: Contribution to journalArticle

Nucleoside Transport Proteins
Trypanosoma brucei brucei
Gene encoding
Cloning
Organism Cloning
21 Citations (Scopus)

Cutting edge: Proteasome involvement in the degradation of unassembled Ig light chains

O'Hare, T., Wiens, G. D., Whitcomb, E. A., Enns, C. & Rittenberg, M., Jul 1 1999, In : Journal of Immunology. 163, 1, p. 11-14 4 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Endoplasmic Reticulum
Light
Proteasome Inhibitors
Biosynthetic Pathways
195 Citations (Scopus)

Cytomegalovirus US2 destroys two components of the MHC class II pathway, preventing recognition by CD4+ T cells

Tomazin, R., Boname, J., Hedge, N. R., Lewinsohn, D., Altschuler, Y., Jones, T. R., Cresswell, P., Nelson, J., Riddell, S. R. & Johnson, D., Sep 1999, In : Nature Medicine. 5, 9, p. 1039-1043 5 p.

Research output: Contribution to journalArticle

T-cells
Cytomegalovirus
Macrophages
T-Lymphocytes
CD4 Antigens
8 Citations (Scopus)

Replacements in the exposed loop of the T15 antibody VH CDR2 affect carrier recognition of PC-containing pathogens

Brown, M., Wiens, G. D., O'Hare, T., Stenzel-Poore, M. & Rittenberg, M., Feb 1999, In : Molecular Immunology. 36, 3, p. 205-211 7 p.

Research output: Contribution to journalArticle

Phosphorylcholine
Antibodies
Ascaris suum
Trichinella spiralis
Streptococcus pneumoniae
102 Citations (Scopus)

Temporal modulation of cytokine expression following focal cerebral ischemia in mice

Hill, J. K., Gunion-Rinker, L., Kulhanek, D., Lessov, N., Kim, S., Clark, W., Dixon, M. P., Nishi, R., Stenzel-Poore, M. & Eckenstein, F. P., Feb 27 1999, In : Brain Research. 820, 1-2, p. 45-54 10 p.

Research output: Contribution to journalArticle

Brain Ischemia
Cytokines
Messenger RNA
E-Selectin
Ischemia
1998
172 Citations (Scopus)

Analysis of the assembly function of the human immunodeficiency virus type 1 gag protein nucleocapsid domain

Zhang, Y., Qian, H., Love, Z. & Barklis, E., Mar 1998, In : Journal of Virology. 72, 3, p. 1782-1789 8 p.

Research output: Contribution to journalArticle

Human Immunodeficiency Virus gag Gene Products
nucleocapsid proteins
Nucleocapsid
nucleocapsid
Human immunodeficiency virus 1
3 Citations (Scopus)

A simple method for determining K(A)s of both low and high affinity IgG antibodies

O'Hare, T. & Rittenberg, M., Sep 1 1998, In : Journal of Immunological Methods. 218, 1-2, p. 161-167 7 p.

Research output: Contribution to journalArticle

Antibody Affinity
Haptens
Immunoglobulin G
Antibodies
Complementarity Determining Regions
2 Citations (Scopus)

Avoiding immunity and apoptosis: Manipulation of the host environment by herpes simplex virus and Epstein-Barr virus

Hill, A. & Masucci, M. G., Apr 1998, In : Seminars in Virology. 8, 5, p. 361-368 8 p.

Research output: Contribution to journalArticle

Herpesviridae
Simplexvirus
Human Herpesvirus 4
Immunity
Apoptosis
56 Citations (Scopus)

Bovine herpesvirus-1 infection affects the peptide transport activity in bovine cells

Hinkley, S., Hill, A. & Srikumaran, S., Jan 1998, In : Virus Research. 53, 1, p. 91-96 6 p.

Research output: Contribution to journalArticle

Bovine Herpesvirus 1
Herpesviridae Infections
Antigen Presentation
Endoplasmic Reticulum
Major Histocompatibility Complex
40 Citations (Scopus)
adenosylhomocysteine nucleosidase
Cloning
Escherichia coli
Organism Cloning
Genes
94 Citations (Scopus)

Cloning of Leishmania nucleoside transporter genes by rescue of a transport-deficient mutant

Vasudevan, G., Carter, N., Drew, M. E., Beverley, S. M., Sanchez, M., Seyfang, A., Ullman, B. & Landfear, S., Aug 18 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 17, p. 9873-9878 6 p.

Research output: Contribution to journalArticle

Nucleoside Transport Proteins
Leishmania
Adenosine
Organism Cloning
Pyrimidine Nucleosides

Cytomegalovirus: Their drive to achieve permanent coexistence with their hosts [1]

Hill, A., 1998, In : Trends in Microbiology. 6, 7, p. 260 1 p.

Research output: Contribution to journalArticle

Cytomegalovirus Infections
Cytomegalovirus
42 Citations (Scopus)

Differential coupling of membrane Ig and CD40 to the extracellularly regulated kinase signaling pathway

Purkerson, J. M. & Parker, D., Mar 1 1998, In : Journal of Immunology. 160, 5, p. 2121-2129 9 p.

Research output: Contribution to journalArticle

Phosphotransferases
Membranes
B-Lymphocytes
Mitogen-Activated Protein Kinase Kinases
Cyclic AMP-Dependent Protein Kinases
74 Citations (Scopus)

Differential regulation of multiple glucose transporter genes in Leishmania mexicana

Burchmore, R. J. S. & Landfear, S., Oct 30 1998, In : Journal of Biological Chemistry. 273, 44, p. 29118-29126 9 p.

Research output: Contribution to journalArticle

Leishmania mexicana
Facilitative Glucose Transport Proteins
Genes
Life Cycle Stages
Life cycle
24 Citations (Scopus)

Harmful somatic mutations: Lessons from the dark side

Wiens, G. D., Roberts, V. A., Whitcomb, E. A., O'Hare, T., Stenzel-Poore, M. & Rittenberg, M., Apr 1998, In : Immunological Reviews. 162, p. 197-209 13 p.

Research output: Contribution to journalArticle

Mutation
Antibodies
B-Lymphocytes
Cell Count
43 Citations (Scopus)

Herpes simplex virus gD and virions accumulate in endosomes by mannose 6-phosphate-dependent and -independent mechanisms

Brunetti, C. R., Dingwell, K. S., Wale, C., Graham, F. L. & Johnson, D., Apr 1998, In : Journal of Virology. 72, 4, p. 3330-3339 10 p.

Research output: Contribution to journalArticle

herpes simplex
endosomes
Endosomes
Simplexvirus
mannose
90 Citations (Scopus)

Herpes simplex virus type 2 ICP47 inhibits human TAP but not mouse tap

Tomazin, R., Van Schoot, N. E. G., Goldsmith, K., Jugovic, P., Sempe, P., Frueh, K. & Johnson, D., 1998, In : Journal of Virology. 72, 3, p. 2560-2563 4 p.

Research output: Contribution to journalArticle

Human herpesvirus 2
Human Herpesvirus 2
mice
herpes simplex
antigen presentation
55 Citations (Scopus)

Herpesvirus evasion of the immune system

Johnson, D. & Hill, A., 1998, In : Current Topics in Microbiology and Immunology. 232, p. 149-177 29 p.

Research output: Contribution to journalArticle

Herpesviridae
Simplexvirus
Cytomegalovirus
Human Herpesvirus 4
Immune System
7 Citations (Scopus)

Inefficient assembly and intracellular accumulation of antibodies with mutations in V(H) CDR2

Martin, T., Wiens, G. D. & Rittenberg, M., Jun 15 1998, In : Journal of Immunology. 160, 12, p. 5963-5970 8 p.

Research output: Contribution to journalArticle

Complementarity Determining Regions
Mutation
Phosphorylcholine
Antibodies
Glycoside Hydrolases
104 Citations (Scopus)

Infected cell protein (ICP)47 enhances herpes simplex virus neurovirulence by blocking the CD8+ T cell response

Goldsmith, K., Chen, W., Johnson, D. & Hendricks, R. L., Feb 2 1998, In : Journal of Experimental Medicine. 187, 3, p. 341-348 8 p.

Research output: Contribution to journalArticle

Simplexvirus
T-Lymphocytes
Human Herpesvirus 1
Proteins
Nude Mice
70 Citations (Scopus)

Inhibition of major histocompatibility complex class I antigen presentation in pig and primate cells by herpes simplex virus type 1 and 2 ICP47

Jugovic, P., Hill, A., Tomazin, R., Ploegh, H. & Johnson, D., Jun 1998, In : Journal of Virology. 72, 6, p. 5076-5084 9 p.

Research output: Contribution to journalArticle

Human herpesvirus 2
Human herpesvirus 1
antigen presentation
Histocompatibility Antigens Class I
Human Herpesvirus 2
55 Citations (Scopus)

Organization of HIV-1 capsid proteins on a lipid monolayer

Barklis, E., McDermott, J., Wilkens, S., Fuller, S. & Thompson, D., Mar 27 1998, In : Journal of Biological Chemistry. 273, 13, p. 7177-7180 4 p.

Research output: Contribution to journalArticle

Capsid Proteins
Viruses
Virion
HIV-1
Monolayers
9 Citations (Scopus)
Moloney murine leukemia virus
Capsid Proteins
Viruses
Nuclear magnetic resonance spectroscopy
HIV-1
143 Citations (Scopus)

The herpes simplex virus gE-gI complex facilitates cell-to-cell spread and binds to components of cell junctions

Dingwell, K. S. & Johnson, D., Nov 1998, In : Journal of Virology. 72, 11, p. 8933-8942 10 p.

Research output: Contribution to journalArticle

intercellular junctions
herpes simplex
Intercellular Junctions
Simplexvirus
viruses
1997
153 Citations (Scopus)

A mouse cytomegalovirus glycoprotein, gp34, forms a complex with folded class I MHC molecules in the ER which is not retained but is transported to the cell surface

Kleijnen, M. F., Huppa, J. B., Lucin, P., Mukherjee, S., Farrell, H., Campbell, A. E., Koszinowski, U. H., Hill, A. & Ploegh, H. L., Feb 17 1997, In : EMBO Journal. 16, 4, p. 685-694 10 p.

Research output: Contribution to journalArticle

Muromegalovirus
Major Histocompatibility Complex
Endoplasmic Reticulum
Molecules
Gene encoding
47 Citations (Scopus)

A role for two hairpin structures as a core RNA encapsidation signal in murine leukemia virus virions

Mougel, M. & Barklis, E., 1997, In : Journal of Virology. 71, 10, p. 8061-8065 5 p.

Research output: Contribution to journalArticle

Murine leukemia virus
Murine Leukemia Viruses
Moloney murine leukemia virus
virion
Virion
36 Citations (Scopus)

Aspartate 19 and glutamate 121 are critical for transport function of the myo-inositol/H+ symporter from Leishmania donovani

Seyfang, A., Kavanaugh, M. P. & Landfear, S., Sep 26 1997, In : Journal of Biological Chemistry. 272, 39, p. 24210-24215 6 p.

Research output: Contribution to journalArticle

Symporters
Leishmania donovani
Inositol
Aspartic Acid
Protons
6 Citations (Scopus)

Cognate T Cell Help for CD40-Deficient B Cells Induces c-myc RNA Expression, but DNA Synthesis Requires an Additional Signal Through Surface Ig

Schrader, C. E., Stavnezer, J., Kikutani, H. & Parker, D., Jan 1 1997, In : Journal of Immunology. 158, 1, p. 153-162 10 p.

Research output: Contribution to journalArticle

B-Lymphocytes
RNA
T-Lymphocytes
DNA
Helper-Inducer T-Lymphocytes
71 Citations (Scopus)

Cytomegaloviruses use multiple mechanisms to elude the host immune response

Wiertz, E., Hill, A., Tortorella, D. & Ploegh, H., 1997, In : Immunology Letters. 57, 1-3, p. 213-216 4 p.

Research output: Contribution to journalArticle

Cytomegalovirus
Glycoproteins
Immune System
Immune Evasion
Histocompatibility Antigens Class I
39 Citations (Scopus)

Cytoskeletal association is important for differential targeting of glucose transporter isoforms in Leishmania

Snapp, E. L. & Landfear, S., Dec 29 1997, In : Journal of Cell Biology. 139, 7, p. 1775-1783 9 p.

Research output: Contribution to journalArticle

Facilitative Glucose Transport Proteins
Leishmania
Protein Isoforms
Cytoskeleton
Membranes
78 Citations (Scopus)

Effects of nucleocapsid mutations on human immunodeficiency virus assembly and RNA encapsidation

Zhang, Y. & Barklis, E., 1997, In : Journal of Virology. 71, 9, p. 6765-6776 12 p.

Research output: Contribution to journalArticle

Virus Assembly
Nucleocapsid
nucleocapsid
Human immunodeficiency virus
HIV
35 Citations (Scopus)

Endotoxin regulates corticotropin-releasing hormone receptor 2 in heart and skeletal muscle

Heldwein, K. A., Duncan, J. E., Stenzel, P., Rittenberg, M. & Stenzel-Poore, M., Aug 8 1997, In : Molecular and Cellular Endocrinology. 131, 2, p. 167-172 6 p.

Research output: Contribution to journalArticle

Corticotropin-Releasing Hormone Receptors
Endotoxins
Muscle
Myocardium
Skeletal Muscle
Virology
HIV-1
2 Citations (Scopus)
Nucleocapsid Proteins
Virology
Retroviridae
RNA
3 Citations (Scopus)

Partial isolation from intact cells of a cell surface-exposed lysophosphatidylinositol-phospholipase C

Birrell, G. B., Hedberg, K. K., Barklis, E. & Griffith, O. H., Jun 15 1997, In : Journal of Cellular Biochemistry. 65, 4, p. 550-564 15 p.

Research output: Contribution to journalArticle

Cell Separation
Type C Phospholipases
Programmable logic controllers
Glycosylphosphatidylinositols
Membrane Proteins
38 Citations (Scopus)

Potentiation of an antimalarial oxidant drug

Winter, R. W., Ignatushchenko, M., Ogundahunsi, O. A. T., Cornell, K. A., Oduola, A. M. J., Hinrichs, D. J. & Riscoe, M., Jul 1997, In : Antimicrobial Agents and Chemotherapy. 41, 7, p. 1449-1454 6 p.

Research output: Contribution to journalArticle

Antimalarials
Oxidants
Ascorbic Acid
Erythrocytes
Plasmodium
45 Citations (Scopus)

Selection of antigen-specific T cells by a single IE(k) peptide combination

Liu, C. P., Parker, D., Kappler, J. & Marrack, P., Nov 3 1997, In : Journal of Experimental Medicine. 186, 9, p. 1441-1450 10 p.

Research output: Contribution to journalArticle

Moths
Cytochromes c
T-Lymphocytes
Antigens
Peptides
21 Citations (Scopus)

Somatic Mutation in VH Complementarity-Determining Region 2 and Framework Region 2: Differential Effects on Antigen Binding and Ig Secretion

Wiens, G. D., Heldwein, K. A., Stenzel-Poore, M. & Rittenberg, M., Aug 1 1997, In : Journal of Immunology. 159, 3, p. 1293-1302 10 p.

Research output: Contribution to journalArticle

Complementarity Determining Regions
Antigens
Mutation
Conserved Sequence
Genes
87 Citations (Scopus)

Structural analysis of membrane-bound retrovirus capsid proteins

Barklis, E., McDermott, J., Wilkens, S., Schabtach, E., Schmid, M. F., Fuller, S., Karanjia, S., Love, Z., Jones, R., Rui, Y., Zhao, X. & Thompson, D., Mar 17 1997, In : EMBO Journal. 16, 6, p. 1199-1213 15 p.

Research output: Contribution to journalArticle

Retroviridae Proteins
Capsid Proteins
Structural analysis
gag Gene Products
Histidine
86 Citations (Scopus)

The active site of ICP47, a herpes simplex virus-encoded inhibitor of the major histocompatibility complex (MHC)-encoded peptide transporter associated with antigen processing (TAP), maps to the NH2-terminal 35 residues

Galocha, B., Hill, A., Barnett, B. C., Dolan, A., Raimondi, A., Cook, R. F., Brunner, J., McGeoch, D. J. & Ploegh, H. L., May 5 1997, In : Journal of Experimental Medicine. 185, 9, p. 1565-1572 8 p.

Research output: Contribution to journalArticle

trypsinogen activation peptide
Simplexvirus
Major Histocompatibility Complex
Catalytic Domain
Immediate-Early Proteins
97 Citations (Scopus)

Xanthones as antimalarial agents; studies of a possible mode of action

Ignatushchenko, M. V., Winter, R. W., Bächinger, H. P., Hinrichs, D. J. & Riscoe, M., Jun 2 1997, In : FEBS Letters. 409, 1, p. 67-73 7 p.

Research output: Contribution to journalArticle

Xanthones
Antimalarials
Heme
Polymerization
Chloroquine
1996
28 Citations (Scopus)

Affinity purification of 5-methylthioadenosine kinase and 5-methylthioribose/ S-adenosylhomocysteine nucleosidase from Klebsiella pneumoniae

Cornell, K. A., Winter, R. W., Tower, P. A. & Riscoe, M., Jul 1 1996, In : Biochemical Journal. 317, 1, p. 285-290 6 p.

Research output: Contribution to journalArticle

adenosylhomocysteine nucleosidase
Klebsiella pneumoniae
Purification
Molecular mass
Enzymes
23 Citations (Scopus)

Analysis of Low Zone Tolerance Induction in Normal and B Cell-Deficient Mice

Baird, A. M. & Parker, D., Sep 1 1996, In : Journal of Immunology. 157, 5, p. 1833-1839 7 p.

Research output: Contribution to journalArticle

B-Lymphocytes
T-Lymphocytes
Self Tolerance
Muramidase
Interleukin-2
6 Citations (Scopus)

Binding of phenylphosphocholine-carrier conjugates to the combining site of antibodies maintains a conformation of the hapten

Barbar, E., Martin, T., Brown, M., Rittenberg, M. & Peyton, D. H., Mar 5 1996, In : Biochemistry. 35, 9, p. 2958-2967 10 p.

Research output: Contribution to journalArticle

Haptens
Conformations
Binding Sites
Antibodies
Catalytic Domain
63 Citations (Scopus)
adenosylhomocysteine nucleosidase
N-Glycosyl Hydrolases
Substrate Specificity
Enzyme Inhibitors
Pemetrexed