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2006

Comprehensive examination of charged intramembrane residues in a nucleoside transporter

Valdés, R., Liu, W., Ullman, B. & Landfear, S. M., Aug 11 2006, In : Journal of Biological Chemistry. 281, 32, p. 22647-22655 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Coordinated function of murine cytomegalovirus genes completely inhibits CTL lysis

Pinto, A. K., Munks, M. W., Koszinowski, U. H. & Hill, A. B., Sep 1 2006, In : Journal of Immunology. 177, 5, p. 3225-3234 10 p.

Research output: Contribution to journalArticle

Open Access
48 Scopus citations

Corticotropin-releasing factor receptor type 2-deficient mice display impaired coping behaviors during stress

Coste, S. C., Heard, A. D., Phillips, T. J. & Stenzel-Poore, M. P., Mar 1 2006, In : Genes, Brain and Behavior. 5, 2, p. 131-138 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Evaluation and lead optimization of anti-malarial acridones

Winter, R. W., Kelly, J. X., Smilkstein, M. J., Dodean, R., Bagby, G. C., Rathbun, R. K., Levin, J. I., Hinrichs, D. & Riscoe, M. K., Sep 1 2006, In : Experimental Parasitology. 114, 1, p. 47-56 10 p.

Research output: Contribution to journalArticle

70 Scopus citations

Four distinct patterns of memory CD8 T cell responses to chronic murine cytomegalovirus infection

Munks, M. W., Cho, K. S., Pinto, A. K., Sierro, S., Klenerman, P. & Hill, A. B., Jul 1 2006, In : Journal of Immunology. 177, 1, p. 450-458 9 p.

Research output: Contribution to journalArticle

Open Access
180 Scopus citations

Functional characterization and subcellular localization of the three malate dehydrogenase isozymes in Leishmania spp.

Leroux, A., Fleming-Canepa, X., Aranda, A., Maugeri, D., Cazzulo, J. J., Sánchez, M. A. & Nowicki, C., Sep 1 2006, In : Molecular and Biochemical Parasitology. 149, 1, p. 74-85 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

GATA transcription factor required for immunity to bacterial and fungal pathogens

Kerry, S., TeKippe, M., Gaddis, N. C. & Aballay, A., Dec 20 2006, In : PloS one. 1, 1, e77.

Research output: Contribution to journalArticle

64 Scopus citations

Genome-wide analysis reveals a highly diverse CD8 T cell response to murine cytomegalovirus

Munks, M. W., Gold, M. C., Zajac, A. L., Doom, C. M., Morello, C. S., Spector, D. H. & Hill, A. B., Mar 15 2006, In : Journal of Immunology. 176, 6, p. 3760-3766 7 p.

Research output: Contribution to journalArticle

Open Access
108 Scopus citations
130 Scopus citations

Herpes simplex virus capsids are transported in neuronal axons without an envelope containing the viral glycoproteins

Snyder, A., Wisner, T. W. & Johnson, D. C., Nov 1 2006, In : Journal of virology. 80, 22, p. 11165-11177 13 p.

Research output: Contribution to journalArticle

42 Scopus citations
58 Scopus citations

HS1 Functions as an Essential Actin-Regulatory Adaptor Protein at the Immune Synapse

Gomez, T. S., McCarney, S. D., Carrizosa, E., Labno, C. M., Comiskey, E. O., Nolz, J. C., Zhu, P., Freedman, B. D., Clark, M. R., Rawlings, D. J., Billadeau, D. D. & Burkhardt, J. K., Jun 1 2006, In : Immunity. 24, 6, p. 741-752 12 p.

Research output: Contribution to journalArticle

150 Scopus citations

Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion

Ryckman, B. J., Jarvis, M. A., Drummond, D. D., Nelson, J. A. & Johnson, D. C., Jan 2006, In : Journal of virology. 80, 2, p. 710-722 13 p.

Research output: Contribution to journalArticle

222 Scopus citations

Imprinting the fate of antigen-reactive B cells through the affinity of the B cell receptor

O'Connor, B. P., Vogel, L. A., Zhang, W., Loo, W., Shnider, D., Lind, E. F., Ratliff, M., Noelle, R. J. & Erickson, L. D., Dec 1 2006, In : Journal of Immunology. 177, 11, p. 7723-7732 10 p.

Research output: Contribution to journalArticle

Open Access
57 Scopus citations

Inhibition of TCR signaling by herpes simplex virus

Sloan, D. D., Han, J. Y., Sandifer, T. K., Stewart, M., Hinz, A. J., Yoon, M., Johnson, D. C., Spear, P. G. & Jerome, K. R., Feb 1 2006, In : Journal of Immunology. 176, 3, p. 1825-1833 9 p.

Research output: Contribution to journalArticle

Open Access
42 Scopus citations

Liver transduction with recombinant adeno-associated virus is primarily restricted by capsid serotype not vector genotype

Grimm, D., Pandey, K., Nakai, H., Storm, T. A. & Kay, M. A., Jan 2006, In : Journal of virology. 80, 1, p. 426-439 14 p.

Research output: Contribution to journalArticle

73 Scopus citations

M. tuberculosis Rv2252 encodes a diacylglycerol kinase involved in the biosynthesis of phosphatidylinositol mannosides (PIMs)

Owens, R. M., Hsu, F. F., VanderVen, B. C., Purdy, G. E., Hesteande, E., Giannakas, P., Sacchettini, J. C., McKinney, J. D., Hill, P. J., Belisle, J. T., Butcher, B. A., Pethe, K. & Russell, D. G., Jun 1 2006, In : Molecular Microbiology. 60, 5, p. 1152-1163 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Mammalian glucose permease GLUT1 facilitates transport of arsenic trioxide and methylarsonous acid

Liu, Z., Sanchez, M. A., Jiang, X., Boles, E., Landfear, S. M. & Rosen, B. P., Dec 15 2006, In : Biochemical and Biophysical Research Communications. 351, 2, p. 424-430 7 p.

Research output: Contribution to journalArticle

86 Scopus citations

Mast cells are essential intermediaries in regulatory T-cell tolerance

Lu, L. F., Lind, E. F., Gondek, D. C., Bennett, K. A., Gleeson, M. W., Pino-Lagos, K., Scott, Z. A., Coyle, A. J., Reed, J. L., Van Snick, J., Strom, T. B., Zheng, X. X. & Noelle, R. J., Aug 31 2006, In : Nature. 442, 7106, p. 997-1002 6 p.

Research output: Contribution to journalArticle

576 Scopus citations

Metabolic changes in glucose transporter-deficient Leishmania mexicana and parasite virulence

Rodríguez-Contreras, D. & Landfear, S. M., Jul 21 2006, In : Journal of Biological Chemistry. 281, 29, p. 20068-20076 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Murine cytomegalovirus interference with antigen presentation contributes to the inability of CD8 T cells to control virus in the salivary gland

Lu, X., Pinto, A. K., Kelly, A. M., Cho, K. S. & Hill, A. B., Apr 1 2006, In : Journal of virology. 80, 8, p. 4200-4202 3 p.

Research output: Contribution to journalArticle

35 Scopus citations
75 Scopus citations

OX40 (CD134) engagement drives differentiation of CD4+ T cells to effector cells

Huddleston, C. A., Weinberg, A. D. & Parker, D. C., May 1 2006, In : European Journal of Immunology. 36, 5, p. 1093-1103 11 p.

Research output: Contribution to journalArticle

37 Scopus citations

Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8

Inagaki, K., Fuess, S., Storm, T. A., Gibson, G. A., Mctiernan, C. F., Kay, M. A. & Nakai, H., Jul 2006, In : Molecular Therapy. 14, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

394 Scopus citations

Silencing herpes simplex virus with a vaginal microbicide

Johnson, D. C., Mar 2 2006, In : New England Journal of Medicine. 354, 9, p. 970-971 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Manno, C. S., Arruda, V. R., Pierce, G. F., Glader, B., Ragni, M., Rasko, J., Ozelo, M. C., Hoots, K., Blatt, P., Konkle, B., Dake, M., Kaye, R., Razavi, M., Zajko, A., Zehnder, J., Nakai, H., Chew, A., Leonard, D., Wright, J. F., Lessard, R. R. & 10 others, Sommer, J. M., Tigges, M., Sabatino, D., Luk, A., Jiang, H., Mingozzi, F., Couto, L., Ertl, H. C., High, K. A. & Kay, M. A., Mar 1 2006, In : Nature medicine. 12, 3, p. 342-347 6 p.

Research output: Contribution to journalArticle

1253 Scopus citations

The Caenorhabditis elegans ABL-1 tyrosine kinase is required for Shigella flexneri pathogenesis

Burton, E. A., Pendergast, A. M. & Aballay, A., Jul 2006, In : Applied and Environmental Microbiology. 72, 7, p. 5043-5051 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

The role of BiP in endoplasmic reticulum-associated degradation of major histocompatibility complex class I heavy chain induced by cytomegalovirus proteins

Hegde, N. R., Chevalier, M. S., Wisner, T. W., Denton, M. C., Shire, K., Frappier, L. & Johnson, D. C., Jul 28 2006, In : Journal of Biological Chemistry. 281, 30, p. 20910-20919 10 p.

Research output: Contribution to journalArticle

44 Scopus citations

The WAVE2 complex regulates actin cytoskeletal reorganization and CRAC-mediated calcium entry during T cell activation

Nolz, J. C., Gomez, T. S., Zhu, P., Li, S., Medeiros, R. B., Shimizu, Y., Burkhardt, J. K., Freedman, B. D. & Billadeau, D. D., Jan 10 2006, In : Current Biology. 16, 1, p. 24-34 11 p.

Research output: Contribution to journalArticle

166 Scopus citations

Toll-like receptors and tolerance to ischaemic injury in the brain

Stevens, S. L. & Stenzel-Poore, M. P., Dec 1 2006, In : Biochemical Society transactions. 34, 6, p. 1352-1355 4 p.

Research output: Contribution to journalArticle

21 Scopus citations
2005

A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells

Nagai, H., Cambronne, E. D., Kagan, J. C., Amor, J. C., Kahn, R. A. & Roy, C. R., Jan 18 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 3, p. 826-831 6 p.

Research output: Contribution to journalArticle

197 Scopus citations

Analysis of human immunodeficiency virus type 1 Gag dimerization-induced assembly

Alfadhli, A., Dhenub, T. C., Still, A. & Barklis, E., Dec 2005, In : Journal of virology. 79, 23, p. 14498-14506 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

A new family of synthetic diterpenes that regulates cytokine synthesis by inhibiting IκBα phosphorylation

Chao, T. H., Lam, T., Vong, B. G., Través, P. G., Hortelano, S., Chowdhury, C., Bahjat, F. R., Lloyd, G. K., Moldawer, L. L., Boscá, L., Palladino, M. A. & Theodorakis, E. A., Jan 1 2005, In : ChemBioChem. 6, 1, p. 133-144 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Assembly of human immunodeficiency virus precursor gag proteins

Huseby, D., Barklis, R. L., Alfadhli, A. & Barklist, E., May 6 2005, In : Journal of Biological Chemistry. 280, 18, p. 17664-17670 7 p.

Research output: Contribution to journalArticle

43 Scopus citations

Characterization of the replication of a baculovirus mutant lacking the DNA polymerase gene

Vanarsdall, A. L., Okano, K. & Rohrmann, G. F., Jan 5 2005, In : Virology. 331, 1, p. 175-180 6 p.

Research output: Contribution to journalArticle

83 Scopus citations

Differential maturation of murine bone-marrow derived dendritic cells with lipopolysaccharide and tumor necrosis factor-α

Efron, P. A., Tsujimoto, H., Bahjat, F. R., Ungaro, R., Debernardis, J., Tannahill, C., Baker, H. V., Edwards, C. K. & Moldawer, L. L., Aug 23 2005, In : Journal of Endotoxin Research. 11, 3, p. 145-160 16 p.

Research output: Contribution to journalArticle

25 Scopus citations

Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4+ CTL

Hegde, N. R., Dunn, C., Lewinsohn, D. M., Jarvis, M. A., Nelson, J. A. & Johnson, D. C., Oct 17 2005, In : Journal of Experimental Medicine. 202, 8, p. 1109-1119 11 p.

Research output: Contribution to journalArticle

60 Scopus citations

Expression profiling of herpesvirus and vaccinia virus proteins using a high-throughput baculovirus screening system

Gao, M., Brufatto, N., Chen, T., Murley, L. L., Thalakada, R., Domagala, M., Beattie, B., Mamelak, D., Athanasopoulos, V., Johnson, D., McFadden, G., Burks, C. & Frappier, L., Nov 1 2005, In : Journal of Proteome Research. 4, 6, p. 2225-2235 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Functional modification of dendritic cells with recombinant adenovirus encoding interleukin 10 for the treatment of sepsis

Oberholzer, A., Oberholzer, C., Efron, P. A., Scumpia, P. O., Uchida, T., Bahjat, K., Ungaro, R., Tannahill, C. L., Murday, M., Bahjat, F. R., Tsai, V., Hutchins, B., Moldawer, L. L., LaFace, D. & Clare-Salzler, M. J., Jun 1 2005, In : Shock. 23, 6, p. 507-515 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Herpes keratitis in the absence of anterograde transport of virus from sensory ganglia to the cornea

Polcicova, K., Biswas, P. S., Banerjee, K., Wisner, T. W., Rouse, B. T. & Johnson, D. C., Aug 9 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 32, p. 11462-11467 6 p.

Research output: Contribution to journalArticle

57 Scopus citations

Kinetics of phosphatidylinositol-3-phosphate acquisition differ between lgG bead-containing phagosomes and Mycobacterium tuberculosis-containing phagosomes

Purdy, G. E., Owens, R. M., Bennett, L., Russell, D. G. & Butcher, B. A., Nov 1 2005, In : Cellular Microbiology. 7, 11, p. 1627-1634 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver

Nakai, H., Wu, X., Fuess, S., Storm, T. A., Munroe, D., Montini, E., Burgess, S. M., Grompe, M. & Kay, M. A., Mar 2005, In : Journal of virology. 79, 6, p. 3606-3614 9 p.

Research output: Contribution to journalArticle

127 Scopus citations

Mice deficient in corticotropin-releasing factor receptor type 2 exhibit normal ethanol-associated behaviors

Sharpe, A. L., Coste, S. C., Burkhart-Kasch, S., Li, N., Stenzel-Poore, M. P. & Phillips, T. J., Sep 1 2005, In : Alcoholism: Clinical and Experimental Research. 29, 9, p. 1601-1609 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Modified infusion procedures affect recombinant adeno-associated virus vector type 2 transduction in the liver

Ohashi, K., Nakai, H., Couto, L. B. & Kay, M. A., Mar 1 2005, In : Human Gene Therapy. 16, 3, p. 299-306 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Mutational analysis of a nucleosidase involved in quorum-sensing autoinducer-2 biosynthesis

Lee, J. E., Luong, W., Huang, D. J. T., Cornell, K. A., Riscoe, M. K. & Howell, P. L., Aug 23 2005, In : Biochemistry. 44, 33, p. 11049-11057 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Mutations affecting cleavage at the p10-capsid protease cleavage site block Rous sarcoma virus replication

Vana, M. L., Chen, A., Boross, P., Weber, I., Colman, D., Barklis, E. & Leis, J., Sep 27 2005, In : Retrovirology. 2, 58.

Research output: Contribution to journalArticle

1 Scopus citations

Neuroprotection by osteopontin in stroke

Meller, R., Stevens, S. L., Minami, M., Cameron, J. A., King, S., Rosenzweig, H., Doyle, K., Lessov, N. S., Simon, R. P. & Stenzel-Poore, M. P., Feb 1 2005, In : Journal of Cerebral Blood Flow and Metabolism. 25, 2, p. 217-225 9 p.

Research output: Contribution to journalArticle

141 Scopus citations

Peptide-specific intercellular transfer of MHC class II to CD4+ T cells directly from the immunological synapse upon cellular dissociation

Wetzel, S. A., McKeithan, T. W. & Parker, D. C., Jan 1 2005, In : Journal of Immunology. 174, 1, p. 80-89 10 p.

Research output: Contribution to journalArticle

Open Access
63 Scopus citations

Regulation of the small GTPase Rap1 and extracellular signal-regulated kinases by the costimulatory molecule CTLA-4

Dillon, T. J., Carey, K. D., Wetzel, S. A., Parker, D. C. & Stork, P. J. S., May 1 2005, In : Molecular and cellular biology. 25, 10, p. 4117-4128 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5′-methylthioadenosine/S- adenosylhomocysteine nucleosidase

Lee, J. E., Singh, V., Evans, G. B., Tyler, P. C., Furneax, R. H., Cornell, K. A., Riscoe, M. K., Schramm, V. L. & Howell, P. L., May 6 2005, In : Journal of Biological Chemistry. 280, 18, p. 18274-18282 9 p.

Research output: Contribution to journalArticle

70 Scopus citations